Aliases & Classifications for Breast Ductal Adenoma

MalaCards integrated aliases for Breast Ductal Adenoma:

Name: Breast Ductal Adenoma 12 15 71

Classifications:



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Disease Ontology 12 DOID:7538
NCIt 49 C40384
UMLS 71 C1511307

Summaries for Breast Ductal Adenoma

Disease Ontology : 12 A breast adenoma that is characterized by a prominent fibrotic capsule and a bilayered tubular component.

MalaCards based summary : Breast Ductal Adenoma is related to adenoma and hormone producing pituitary cancer, and has symptoms including nipple discharge An important gene associated with Breast Ductal Adenoma is PRKAR1A (Protein Kinase CAMP-Dependent Type I Regulatory Subunit Alpha), and among its related pathways/superpathways are Aldosterone synthesis and secretion and G alpha (s) signalling events. Affiliated tissues include breast, pituitary and cortex.

Related Diseases for Breast Ductal Adenoma

Diseases related to Breast Ductal Adenoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 29)
# Related Disease Score Top Affiliating Genes
1 adenoma 10.2
2 hormone producing pituitary cancer 10.1 PRKAR1A POMC
3 hyperpituitarism 10.0 PRKAR1A POMC
4 testicular disease 10.0 PRKAR1A PDE11A
5 acth-secreting pituitary adenoma 10.0 PRKAR1A POMC
6 acth-independent macronodular adrenal hyperplasia 10.0 PDE11A ARMC5
7 growth hormone secreting pituitary adenoma 10.0 PRKAR1A POMC
8 functioning pituitary adenoma 10.0 PRKAR1A POMC
9 adrenal cortical carcinoma 10.0 PRKAR1A POMC
10 breast fibroadenoma 10.0
11 adrenal cortical adenoma 10.0 PRKAR1A POMC
12 adrenal adenoma 9.9 PRKAR1A POMC
13 breast adenoma 9.9 PRKAR1A PDE8B PDE11A
14 pituitary gland disease 9.9 PRKAR1A POMC
15 mccune-albright syndrome 9.9 PRKAR1A PDE8B PDE11A
16 endocrine organ benign neoplasm 9.8 PRKAR1A POMC
17 testicular sex cord-stromal neoplasm 9.8 PRKAR1A POMC PDE11A
18 sex cord-gonadal stromal tumor 9.8 PRKAR1A POMC PDE11A
19 pituitary adenoma, prolactin-secreting 9.8 PRKAR1A POMC
20 adrenal carcinoma 9.7 PRKAR1A POMC ARMC5
21 primary hyperparathyroidism 9.6 PRKAR1A POMC
22 basophil adenoma 9.5 PRKAR1A POMC PDE8B PDE11A
23 acth-independent cushing syndrome 9.5 PRKAR1A PDE8B PDE11A ARMC5
24 melanotic neurilemmoma 9.5 PRKAR1A POMC PDE11A F10
25 adrenal gland disease 9.4 PRKAR1A POMC PDE11A ARMC5
26 conn's syndrome 9.4 PRKAR1A POMC PDE11A ARMC5
27 adrenal cortex disease 9.1 PRKAR1A POMC PDE8B PDE11A ARMC5
28 primary pigmented nodular adrenocortical disease 8.2 PRKX PRKAR1A POMC PDE8B PDE11A F10
29 carney complex variant 8.2 PRKX PRKAR1A POMC PDE8B PDE11A F10

Graphical network of the top 20 diseases related to Breast Ductal Adenoma:



Diseases related to Breast Ductal Adenoma

Symptoms & Phenotypes for Breast Ductal Adenoma

UMLS symptoms related to Breast Ductal Adenoma:


nipple discharge

Drugs & Therapeutics for Breast Ductal Adenoma

Search Clinical Trials , NIH Clinical Center for Breast Ductal Adenoma

Genetic Tests for Breast Ductal Adenoma

Anatomical Context for Breast Ductal Adenoma

MalaCards organs/tissues related to Breast Ductal Adenoma:

40
Breast, Pituitary, Cortex, Adrenal Gland, Adrenal Cortex

Publications for Breast Ductal Adenoma

Articles related to Breast Ductal Adenoma:

# Title Authors PMID Year
1
Malignant transformation of breast ductal adenoma: a diagnostic pitfall. 61
26712676 2015
2
Mitotane and Carney Complex: ten years follow-up of a low-dose mitotane regimen inducing a sustained correction of hypercortisolism. 61
25402388 2015
3
Intraductal fibroadenoma and intraductal phyllodes tumour--a part of the spectrum of the breast ductal adenoma? 61
20013344 2010
4
Rare syndromes. 61
16828412 2006

Variations for Breast Ductal Adenoma

Expression for Breast Ductal Adenoma

Search GEO for disease gene expression data for Breast Ductal Adenoma.

Pathways for Breast Ductal Adenoma

Pathways related to Breast Ductal Adenoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.03 POMC PDE8B PDE11A ARMC5
2 10.96 POMC PDE8B PDE11A
3 10.77 PRKAR1A POMC

GO Terms for Breast Ductal Adenoma

Cellular components related to Breast Ductal Adenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cAMP-dependent protein kinase complex GO:0005952 8.62 PRKX PRKAR1A

Molecular functions related to Breast Ductal Adenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 phosphoric diester hydrolase activity GO:0008081 8.96 PDE8B PDE11A
2 3',5'-cyclic-GMP phosphodiesterase activity GO:0047555 8.62 PRKAR1A PDE11A

Sources for Breast Ductal Adenoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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