Aliases & Classifications for Breast Ductal Adenoma

MalaCards integrated aliases for Breast Ductal Adenoma:

Name: Breast Ductal Adenoma 12 15 72

Classifications:



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Disease Ontology 12 DOID:7538
NCIt 50 C40384
UMLS 72 C1511307

Summaries for Breast Ductal Adenoma

Disease Ontology : 12 A breast adenoma that is characterized by a prominent fibrotic capsule and a bilayered tubular component.

MalaCards based summary : Breast Ductal Adenoma is related to adenoma and male reproductive organ benign neoplasm, and has symptoms including nipple discharge An important gene associated with Breast Ductal Adenoma is PRKAR1A (Protein Kinase CAMP-Dependent Type I Regulatory Subunit Alpha), and among its related pathways/superpathways are ADP signalling through P2Y purinoceptor 12 and Glucocorticoid receptor regulatory network. Affiliated tissues include breast, and related phenotypes are Downregulation of Wnt pathway after Wnt3A stimulation and integument

Related Diseases for Breast Ductal Adenoma

Diseases related to Breast Ductal Adenoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 55)
# Related Disease Score Top Affiliating Genes
1 adenoma 30.0 PRL POMC
2 male reproductive organ benign neoplasm 10.1 PRKAR1A POMC
3 adrenal cortical adenoma 10.0 PRKAR1A POMC
4 adrenal gland disease 10.0 PRKAR1A POMC
5 breast fibroadenoma 10.0
6 primary pigmented nodular adrenocortical disease 9.9 PRKAR1A POMC
7 pituitary infarct 9.9 PRL POMC
8 chiasmal syndrome 9.9 PRL POMC
9 adenohypophysitis 9.9 PRL POMC
10 hypothalamic disease 9.9 PRL POMC
11 pituitary carcinoma 9.9 PRL POMC
12 pituitary apoplexy 9.9 PRL POMC
13 tuberculum sellae meningioma 9.9 PRL POMC
14 sella turcica neoplasm 9.9 PRL POMC
15 empty sella syndrome 9.9 PRL POMC
16 sheehan syndrome 9.9 PRL POMC
17 nelson syndrome 9.9 PRL POMC
18 hyperpituitarism 9.9 PRL POMC
19 acth-secreting pituitary adenoma 9.9 PRL POMC
20 tsh producing pituitary tumor 9.9 PRL POMC
21 functioning pituitary adenoma 9.9 PRL POMC
22 abducens nerve disease 9.8 PRL POMC
23 diabetes insipidus, neurohypophyseal 9.8 PRL POMC
24 diabetes insipidus 9.8 PRL POMC
25 premenstrual tension 9.8 PRL POMC
26 chromophobe adenoma 9.8 PRL POMC
27 hypothyroidism, congenital, nongoitrous, 4 9.8 PRL POMC
28 hypothyroidism 9.8 PRL POMC
29 pituitary-dependent cushing's disease 9.8 PRL POMC
30 adrenal rest tumor 9.8 PRL POMC
31 pituitary tumors 9.8 PRL POMC
32 endocrine organ benign neoplasm 9.8 PRL POMC
33 gynecomastia 9.8 PRL POMC
34 growth hormone secreting pituitary adenoma 9.8 PRL PRKAR1A
35 pituitary hormone deficiency, combined, 2 9.8 PRL POMC
36 thyroid gland disease 9.7 PRL POMC
37 multiple endocrine neoplasia, type i 9.7 PRL PRKAR1A
38 pituitary gland disease 9.7 PRL POMC
39 multiple endocrine neoplasia, type iv 9.7 PRL PRKAR1A
40 hyperprolactinemia 9.7 PRL POMC
41 hyperandrogenism 9.7 PRL POMC
42 cell type benign neoplasm 9.7 PRL POMC
43 amenorrhea 9.7 PRL POMC
44 adrenocortical carcinoma, hereditary 9.7 PRKAR1A POMC
45 hypopituitarism 9.7 PRL POMC
46 gonadal disease 9.6 PRL POMC
47 acromegaly 9.6 PRL POMC
48 acquired metabolic disease 9.6 PRL POMC
49 major depressive disorder 9.5 PRL POMC
50 primary hyperparathyroidism 9.4 PRL PRKAR1A

Graphical network of the top 20 diseases related to Breast Ductal Adenoma:



Diseases related to Breast Ductal Adenoma

Symptoms & Phenotypes for Breast Ductal Adenoma

UMLS symptoms related to Breast Ductal Adenoma:


nipple discharge

GenomeRNAi Phenotypes related to Breast Ductal Adenoma according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Downregulation of Wnt pathway after Wnt3A stimulation GR00057-A-2 8.62 POMC PRKAR1A

MGI Mouse Phenotypes related to Breast Ductal Adenoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 integument MP:0010771 9.33 POMC PRKAR1A PRL
2 liver/biliary system MP:0005370 9.13 POMC PRKAR1A PRL
3 neoplasm MP:0002006 8.8 POMC PRKAR1A PRL

Drugs & Therapeutics for Breast Ductal Adenoma

Search Clinical Trials , NIH Clinical Center for Breast Ductal Adenoma

Genetic Tests for Breast Ductal Adenoma

Anatomical Context for Breast Ductal Adenoma

MalaCards organs/tissues related to Breast Ductal Adenoma:

41
Breast

Publications for Breast Ductal Adenoma

Articles related to Breast Ductal Adenoma:

# Title Authors PMID Year
1
Malignant transformation of breast ductal adenoma: a diagnostic pitfall. 38
26712676 2015
2
Mitotane and Carney Complex: ten years follow-up of a low-dose mitotane regimen inducing a sustained correction of hypercortisolism. 38
25402388 2015
3
Intraductal fibroadenoma and intraductal phyllodes tumour--a part of the spectrum of the breast ductal adenoma? 38
20013344 2010
4
Rare syndromes. 38
16828412 2006

Variations for Breast Ductal Adenoma

Expression for Breast Ductal Adenoma

Search GEO for disease gene expression data for Breast Ductal Adenoma.

Pathways for Breast Ductal Adenoma

GO Terms for Breast Ductal Adenoma

Cellular components related to Breast Ductal Adenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 secretory granule GO:0030141 8.32 POMC

Molecular functions related to Breast Ductal Adenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 8.62 PRL POMC

Sources for Breast Ductal Adenoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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