MCID: BRS008
MIFTS: 30

Breast Giant Fibroadenoma

Categories: Cancer diseases

Aliases & Classifications for Breast Giant Fibroadenoma

MalaCards integrated aliases for Breast Giant Fibroadenoma:

Name: Breast Giant Fibroadenoma 12 15
Giant Fibroadenoma of Breast 12 73
Giant Fibroadenoma 12 73

Classifications:



External Ids:

Disease Ontology 12 DOID:7223
NCIt 50 C4273

Summaries for Breast Giant Fibroadenoma

Disease Ontology : 12 A breast fibroadenoma that is larger than 5 cm.

MalaCards based summary : Breast Giant Fibroadenoma, also known as giant fibroadenoma of breast, is related to breast fibroadenoma and heart sarcoma. An important gene associated with Breast Giant Fibroadenoma is BCS1L (BCS1 Homolog, Ubiquinol-Cytochrome C Reductase Complex Chaperone), and among its related pathways/superpathways are Pathways in cancer and Senescence and Autophagy in Cancer. Affiliated tissues include brain, bone and colon, and related phenotypes are homeostasis/metabolism and mortality/aging

Related Diseases for Breast Giant Fibroadenoma

Diseases related to Breast Giant Fibroadenoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 59)
# Related Disease Score Top Affiliating Genes
1 breast fibroadenoma 10.3
2 heart sarcoma 10.2 GFPT1 WT1
3 tumor predisposition syndrome 10.1 BRCA2 PMS2
4 peritoneum cancer 10.1 BRCA2 WT1
5 lynch syndrome i 10.1 BRCA2 PMS2
6 spinal cord astrocytoma 10.1 CD44 MGMT
7 sebaceous adenoma 10.1 ESR1 PMS2
8 peritoneal benign neoplasm 10.1 ESR1 WT1
9 diffuse peritoneal leiomyomatosis 10.1 ESR1 WT1
10 dysgerminoma of ovary 10.1 BRCA2 WT1
11 mucinoses 10.1 CD44 IFNG
12 female reproductive endometrioid cancer 10.0 ESR1 WT1
13 synchronous bilateral breast carcinoma 10.0 BRCA2 ESR1
14 breast cancer 10.0
15 breast reconstruction 10.0
16 primary peritoneal carcinoma 10.0 BRCA2 IFNG
17 fallopian tube squamous cell carcinoma 10.0 CDKN2A WT1
18 anaplastic oligodendroglioma 10.0 CDKN2A MGMT
19 melanomatosis 10.0 CDKN2A WT1
20 fallopian tube carcinoma 10.0 BRCA2 ESR1
21 sarcomatoid mesothelioma 10.0 CDKN2A WT1
22 dysplastic nevus syndrome 10.0 BRCA2 CDKN2A
23 uterine sarcoma 10.0 ESR1 WT1
24 pleural cancer 9.9 CDKN2A WT1
25 gastric adenosquamous carcinoma 9.9 CD44 CDKN2A
26 malignant ovarian surface epithelial-stromal neoplasm 9.9 BRCA2 ESR1 WT1
27 ovary epithelial cancer 9.9 BRCA2 ESR1 WT1
28 colonic disease 9.9 CD44 ESR1 PMS2
29 bartholin's gland benign neoplasm 9.9 CDKN2A ESR1
30 endometrial squamous cell carcinoma 9.9 CDKN2A ESR1
31 endometrial mucinous adenocarcinoma 9.9 CDKN2A ESR1
32 adenoid basal cell carcinoma 9.9 CDKN2A ESR1
33 endocervical carcinoma 9.9 CDKN2A ESR1
34 ovarian cancer 1 9.9 BRCA2 WT1
35 benign breast phyllodes tumor 9.9
36 hypertrichosis 9.9
37 brain cancer 9.9 BRCA2 CD44 MGMT PMS2
38 breast carcinoma in situ 9.9 BRCA2 ESR1
39 central nervous system lymphoma 9.9 CDKN2A MGMT
40 gastrointestinal system cancer 9.8 CD44 CDKN2A PMS2
41 supratentorial cancer 9.8 CD44 CDKN2A MGMT
42 cerebrum cancer 9.8 CD44 CDKN2A MGMT
43 wilms tumor 1 9.8 BRCA2 ESR1 WT1
44 uterine anomalies 9.8 CDKN2A ESR1 PMS2
45 peritoneal mesothelioma 9.8 CDKN2A ESR1 WT1
46 glioblastoma multiforme 9.8 CD44 CDKN2A MGMT
47 in situ carcinoma 9.8 CDKN2A ESR1
48 gastrointestinal system disease 9.8 CD44 CDKN2A IFNG
49 glycogen-rich clear cell breast carcinoma 9.8 BRCA2 CDKN2A ESR1
50 pre-malignant neoplasm 9.8 BRCA2 CDKN2A ESR1

Graphical network of the top 20 diseases related to Breast Giant Fibroadenoma:



Diseases related to Breast Giant Fibroadenoma

Symptoms & Phenotypes for Breast Giant Fibroadenoma

MGI Mouse Phenotypes related to Breast Giant Fibroadenoma:

46 (show all 17)
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.24 BCS1L BRCA2 CD44 CDKN2A ESR1 IFNG
2 mortality/aging MP:0010768 10.21 BCS1L BRCA2 CD44 CDKN2A ESR1 GFPT1
3 endocrine/exocrine gland MP:0005379 10.19 BCS1L BRCA2 CD44 CDKN2A ESR1 IFNG
4 cellular MP:0005384 10.17 BCS1L BRCA2 CD44 CDKN2A ESR1 IFNG
5 growth/size/body region MP:0005378 10.13 BCS1L BRCA2 CD44 CDKN2A ESR1 IFNG
6 hematopoietic system MP:0005397 10.11 BRCA2 CD44 CDKN2A ESR1 GFPT1 IFNG
7 immune system MP:0005387 10.08 BRCA2 CD44 CDKN2A ESR1 GFPT1 IFNG
8 liver/biliary system MP:0005370 10.06 BCS1L CD44 CDKN2A ESR1 IFNG PMS2
9 digestive/alimentary MP:0005381 10.03 BRCA2 CD44 CDKN2A ESR1 IFNG PMS2
10 embryo MP:0005380 10.02 BRCA2 CDKN2A ESR1 IFNG PARVA WT1
11 neoplasm MP:0002006 9.97 BRCA2 CD44 CDKN2A ESR1 IFNG MGMT
12 muscle MP:0005369 9.88 CD44 CDKN2A ESR1 IFNG PARVA WT1
13 normal MP:0002873 9.73 BRCA2 CD44 ESR1 IFNG UROD WT1
14 no phenotypic analysis MP:0003012 9.72 CDKN2A ESR1 IFNG MGMT WT1
15 renal/urinary system MP:0005367 9.63 BCS1L CD44 ESR1 IFNG PARVA WT1
16 reproductive system MP:0005389 9.56 BCS1L BRCA2 CD44 CDKN2A ESR1 IFNG
17 respiratory system MP:0005388 9.1 CD44 CDKN2A ESR1 IFNG MGMT WT1

Drugs & Therapeutics for Breast Giant Fibroadenoma

Search Clinical Trials , NIH Clinical Center for Breast Giant Fibroadenoma

Genetic Tests for Breast Giant Fibroadenoma

Anatomical Context for Breast Giant Fibroadenoma

MalaCards organs/tissues related to Breast Giant Fibroadenoma:

41
Brain, Bone, Colon, Heart, Ovary, Spinal Cord

Publications for Breast Giant Fibroadenoma

Articles related to Breast Giant Fibroadenoma:

# Title Authors Year
1
Surgical excision of the breast giant fibroadenoma under regional anesthesia by Pecs II and internal intercostal plane block: a case report and brief technical description: a case report. ( 28184271 )
2017
2
Giant fibroadenoma of breast in an adolescent girl. ( 23071885 )
2012
3
An extraordinary breast giant fibroadenoma (cystosarcoma phyllodes) in a female adolescent. ( 6097413 )
1984

Variations for Breast Giant Fibroadenoma

Expression for Breast Giant Fibroadenoma

Search GEO for disease gene expression data for Breast Giant Fibroadenoma.

Pathways for Breast Giant Fibroadenoma

Pathways related to Breast Giant Fibroadenoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 12.18 BRCA2 CDKN2A ESR1 IFNG
2 11.16 CD44 CDKN2A IFNG
3 10.82 BRCA2 ESR1
4 10.62 ESR1 IFNG WT1

GO Terms for Breast Giant Fibroadenoma

Cellular components related to Breast Giant Fibroadenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nucleoplasm GO:0005654 9.5 BRCA2 CDKN2A ESR1 MGMT PMS2 UROD
2 cytosol GO:0005829 9.28 BRCA2 CD44 CDKN2A ESR1 GFPT1 PARVA

Biological processes related to Breast Giant Fibroadenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of transcription, DNA-templated GO:0045893 9.26 BRCA2 CDKN2A ESR1 WT1
2 positive regulation of smooth muscle cell apoptotic process GO:0034393 8.62 CDKN2A IFNG

Sources for Breast Giant Fibroadenoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....