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MCID: BRS008
MIFTS: 29

Breast Giant Fibroadenoma

Categories: Cancer diseases
Genes Tissues Related diseases Publications Pathways
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Aliases & Classifications for Breast Giant Fibroadenoma

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MalaCards integrated aliases for Breast Giant Fibroadenoma:

Name: Breast Giant Fibroadenoma 12 15
Giant Fibroadenoma of Breast 12 74
Giant Fibroadenoma 12 74

Classifications:

MalaCards categories:
Global: Cancer diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:7223
NCIt 51 C4273
Sources

Summaries for Breast Giant Fibroadenoma

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Disease Ontology : 12 A breast fibroadenoma that is larger than 5 cm.

MalaCards based summary : Breast Giant Fibroadenoma, also known as giant fibroadenoma of breast, is related to breast fibroadenoma and heart sarcoma. An important gene associated with Breast Giant Fibroadenoma is DNAAF1 (Dynein Axonemal Assembly Factor 1), and among its related pathways/superpathways are Pathways in cancer and Senescence and Autophagy in Cancer. Affiliated tissues include breast, ovary and brain, and related phenotypes are homeostasis/metabolism and mortality/aging

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Related Diseases for Breast Giant Fibroadenoma

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Diseases related to Breast Giant Fibroadenoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 56)
# Related Disease Score Top Affiliating Genes
1 breast fibroadenoma 10.2
2 heart sarcoma 10.2 GFPT1 WT1
3 tumor predisposition syndrome 10.2 BRCA2 PMS2
4 peritoneum cancer 10.2 BRCA2 WT1
5 spinal cord astrocytoma 10.1 CD44 MGMT
6 fallopian tube squamous cell carcinoma 10.1 CDKN2A WT1
7 anaplastic oligodendroglioma 10.1 CDKN2A MGMT
8 lynch syndrome i 10.1 BRCA2 PMS2
9 melanomatosis 10.1 CDKN2A WT1
10 mucinoses 10.1 CD44 IFNG
11 breast cancer 10.1
12 breast reconstruction 10.1
13 sarcomatoid mesothelioma 10.1 CDKN2A WT1
14 dysplastic nevus syndrome 10.0 BRCA2 CDKN2A
15 primary peritoneal carcinoma 10.0 BRCA2 IFNG
16 sebaceous adenoma 10.0 ESR1 PMS2
17 aseptic meningitis 10.0 CD44 IFNG
18 pleural cancer 10.0 CDKN2A WT1
19 gastric adenosquamous carcinoma 10.0 CD44 CDKN2A
20 dysgerminoma of ovary 10.0 BRCA2 WT1
21 peritoneal benign neoplasm 10.0 ESR1 WT1
22 diffuse peritoneal leiomyomatosis 10.0 ESR1 WT1
23 female reproductive endometrioid cancer 9.9 ESR1 WT1
24 synchronous bilateral breast carcinoma 9.9 BRCA2 ESR1
25 benign breast phyllodes tumor 9.9
26 hypertrichosis 9.9
27 gastrointestinal system cancer 9.9 CD44 CDKN2A PMS2
28 supratentorial cancer 9.9 CD44 CDKN2A MGMT
29 cerebrum cancer 9.9 CD44 CDKN2A MGMT
30 bartholin's gland benign neoplasm 9.8 CDKN2A ESR1
31 endometrial squamous cell carcinoma 9.8 CDKN2A ESR1
32 endometrial mucinous adenocarcinoma 9.8 CDKN2A ESR1
33 adenoid basal cell carcinoma 9.8 CDKN2A ESR1
34 endocervical carcinoma 9.8 CDKN2A ESR1
35 brain cancer 9.8 BRCA2 CD44 MGMT PMS2
36 fallopian tube carcinoma 9.8 BRCA2 ESR1
37 malignant ovarian surface epithelial-stromal neoplasm 9.8 BRCA2 ESR1 WT1
38 ovary epithelial cancer 9.8 BRCA2 ESR1 WT1
39 colonic disease 9.8 CD44 ESR1 PMS2
40 gastrointestinal system disease 9.8 CD44 CDKN2A IFNG
41 glioblastoma multiforme 9.7 CD44 CDKN2A MGMT
42 lynch syndrome 9.7 BRCA2 CDKN2A MGMT PMS2
43 uterine sarcoma 9.7 ESR1 WT1
44 uterine anomalies 9.7 CDKN2A ESR1 PMS2
45 peritoneal mesothelioma 9.7 CDKN2A ESR1 WT1
46 glycogen-rich clear cell breast carcinoma 9.6 BRCA2 CDKN2A ESR1
47 pre-malignant neoplasm 9.6 BRCA2 CDKN2A ESR1
48 female reproductive system disease 9.6 BRCA2 CDKN2A ESR1
49 wilms tumor 1 9.6 BRCA2 ESR1 WT1
50 pancreas adenocarcinoma 9.5 BRCA2 CD44 CDKN2A IFNG

Graphical network of the top 20 diseases related to Breast Giant Fibroadenoma:



Diseases related to Breast Giant Fibroadenoma
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Symptoms & Phenotypes for Breast Giant Fibroadenoma

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MGI Mouse Phenotypes related to Breast Giant Fibroadenoma:

47 (show all 15)
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.22 BCS1L BRCA2 CD44 CDKN2A ESR1 IFNG
2 mortality/aging MP:0010768 10.22 BCS1L BRCA2 CD44 CDKN2A DNAAF1 ESR1
3 endocrine/exocrine gland MP:0005379 10.16 BCS1L BRCA2 CD44 CDKN2A ESR1 IFNG
4 cellular MP:0005384 10.15 BCS1L BRCA2 CD44 CDKN2A ESR1 IFNG
5 hematopoietic system MP:0005397 10.1 BRCA2 CD44 CDKN2A ESR1 GFPT1 IFNG
6 immune system MP:0005387 10.06 BRCA2 CD44 CDKN2A ESR1 GFPT1 IFNG
7 liver/biliary system MP:0005370 10.03 BCS1L CD44 CDKN2A ESR1 IFNG PMS2
8 digestive/alimentary MP:0005381 10.01 BRCA2 CD44 CDKN2A ESR1 IFNG PMS2
9 embryo MP:0005380 10 BRCA2 CDKN2A ESR1 IFNG PARVA WT1
10 neoplasm MP:0002006 9.92 BRCA2 CD44 CDKN2A ESR1 IFNG MGMT
11 muscle MP:0005369 9.85 CD44 CDKN2A ESR1 IFNG PARVA WT1
12 reproductive system MP:0005389 9.76 BCS1L BRCA2 CD44 CDKN2A ESR1 IFNG
13 renal/urinary system MP:0005367 9.73 BCS1L CD44 ESR1 IFNG PARVA WT1
14 respiratory system MP:0005388 9.43 CD44 CDKN2A ESR1 IFNG MGMT WT1
15 skeleton MP:0005390 9.1 BRCA2 CD44 CDKN2A DNAAF1 ESR1 IFNG
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Drugs & Therapeutics for Breast Giant Fibroadenoma

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Search Clinical Trials , NIH Clinical Center for Breast Giant Fibroadenoma

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Genetic Tests for Breast Giant Fibroadenoma

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Anatomical Context for Breast Giant Fibroadenoma

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MalaCards organs/tissues related to Breast Giant Fibroadenoma:

42
Breast, Ovary, Brain, Colon, Bone, Heart, Spinal Cord
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Publications for Breast Giant Fibroadenoma

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Articles related to Breast Giant Fibroadenoma:

# Title Authors Year
1
Surgical excision of the breast giant fibroadenoma under regional anesthesia by Pecs II and internal intercostal plane block: a case report and brief technical description: a case report. ( 28184271 )
2017
2
Giant fibroadenoma of breast in an adolescent girl. ( 23071885 )
2012
3
An extraordinary breast giant fibroadenoma (cystosarcoma phyllodes) in a female adolescent. ( 6097413 )
1984
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Variations for Breast Giant Fibroadenoma

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Expression for Breast Giant Fibroadenoma

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Search GEO for disease gene expression data for Breast Giant Fibroadenoma.
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Pathways for Breast Giant Fibroadenoma

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Pathways related to Breast Giant Fibroadenoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Pathways in cancer 38
12.18 BRCA2 CDKN2A ESR1 IFNG
2
Senescence and Autophagy in Cancer 1
11.16 CD44 CDKN2A IFNG
3
FOXM1 transcription factor network 1
10.82 BRCA2 ESR1
4
Regulation of Telomerase 1
10.62 ESR1 IFNG WT1
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GO Terms for Breast Giant Fibroadenoma

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Cellular components related to Breast Giant Fibroadenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytosol GO:0005829 9.32 BRCA2 CD44 CDKN2A DNAAF1 ESR1 GFPT1

Biological processes related to Breast Giant Fibroadenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of smooth muscle cell apoptotic process GO:0034393 8.62 CDKN2A IFNG
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Sources for Breast Giant Fibroadenoma

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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