Breast Giant Fibroadenoma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Breast Giant Fibroadenoma

MalaCards integrated aliases for Breast Giant Fibroadenoma:

Name: Breast Giant Fibroadenoma ¹² ¹⁵

Giant Fibroadenoma of Breast ¹² ⁷¹

Giant Fibroadenoma ¹² ⁷¹

Classifications:

MalaCards categories:
Global: Cancer diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:7223

NCIt ⁵⁰ C4273

SNOMED-CT ⁶⁷ 254846003

UMLS ⁷¹ C0334500 C0346157

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Summaries for Breast Giant Fibroadenoma

Disease Ontology : ¹² A breast fibroadenoma that is larger than 5 cm.

MalaCards based summary : Breast Giant Fibroadenoma, also known as giant fibroadenoma of breast, is related to benign breast phyllodes tumor and breast disease. An important gene associated with Breast Giant Fibroadenoma is PARVA (Parvin Alpha). Affiliated tissues include breast, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

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Related Diseases for Breast Giant Fibroadenoma

Diseases related to Breast Giant Fibroadenoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 23)

#	Related Disease	Score	Top Affiliating Genes
1	benign breast phyllodes tumor	10.4
2	breast disease	10.2
3	breast fibroadenoma	10.2
4	ptosis	10.1
5	congenital heart defects, hamartomas of tongue, and polysyndactyly	9.9
6	hypertrophy of breast	9.9
7	mastitis	9.9
8	breast pericanalicular fibroadenoma	9.9
9	adenofibroma	9.9
10	carcinosarcoma	9.9
11	gigantomastia	9.9
12	prolactin producing pituitary tumor	9.8	PRL MGMT
13	thoracic benign neoplasm	9.8	PRL MED12
14	acidophil adenoma	9.8	PRL MGMT
15	nelson syndrome	9.8	PRL MGMT
16	breast benign neoplasm	9.7	PRL MED12
17	partial third-nerve palsy	9.7	PRL MGMT
18	uterine benign neoplasm	9.7	PRL MED12
19	acth-secreting pituitary adenoma	9.7	PRL MGMT
20	oligodendroglioma	9.7	PMS2 MGMT
21	reproductive organ benign neoplasm	9.7	PRL MED12
22	neurofibromatosis, type i	9.6	PMS2 MGMT
23	pituitary carcinoma	9.4	PRL PMS2 MGMT

Graphical network of the top 20 diseases related to Breast Giant Fibroadenoma:

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Symptoms & Phenotypes for Breast Giant Fibroadenoma

GenomeRNAi Phenotypes related to Breast Giant Fibroadenoma according to GeneCards Suite gene sharing:

²⁶ (show all 35)

#	Description	GenomeRNAi Source Accession	Score	Top Affiliating Genes
1	Increased shRNA abundance (Z-score > 2)	GR00366-A-104	9.94	MED12
2	Increased shRNA abundance (Z-score > 2)	GR00366-A-108	9.94	MED12
3	Increased shRNA abundance (Z-score > 2)	GR00366-A-112	9.94	TCEAL1
4	Increased shRNA abundance (Z-score > 2)	GR00366-A-115	9.94	MED12
5	Increased shRNA abundance (Z-score > 2)	GR00366-A-14	9.94	PMS2
6	Increased shRNA abundance (Z-score > 2)	GR00366-A-153	9.94	MED12
7	Increased shRNA abundance (Z-score > 2)	GR00366-A-185	9.94	MED12
8	Increased shRNA abundance (Z-score > 2)	GR00366-A-19	9.94	PMS2
9	Increased shRNA abundance (Z-score > 2)	GR00366-A-190	9.94	MED12
10	Increased shRNA abundance (Z-score > 2)	GR00366-A-197	9.94	PMS2
11	Increased shRNA abundance (Z-score > 2)	GR00366-A-207	9.94	PMS2
12	Increased shRNA abundance (Z-score > 2)	GR00366-A-23	9.94	MED12
13	Increased shRNA abundance (Z-score > 2)	GR00366-A-26	9.94	MED12
14	Increased shRNA abundance (Z-score > 2)	GR00366-A-34	9.94	MED12
15	Increased shRNA abundance (Z-score > 2)	GR00366-A-42	9.94	TCEAL1
16	Increased shRNA abundance (Z-score > 2)	GR00366-A-49	9.94	PMS2
17	Increased shRNA abundance (Z-score > 2)	GR00366-A-7	9.94	TCEAL1
18	Increased shRNA abundance (Z-score > 2)	GR00366-A-70	9.94	MED12 TCEAL1
19	Increased shRNA abundance (Z-score > 2)	GR00366-A-87	9.94	TCEAL1
20	Increased shRNA abundance (Z-score > 2)	GR00366-A-89	9.94	MED12
21	Increased shRNA abundance (Z-score > 2)	GR00366-A-9	9.94	MED12
22	Increased shRNA abundance (Z-score > 2)	GR00366-A-99	9.94	TCEAL1
23	Decreased shRNA abundance (Z-score < -2)	GR00366-A-104	9.8	PMS2
24	Decreased shRNA abundance (Z-score < -2)	GR00366-A-105	9.8	PMS2
25	Decreased shRNA abundance (Z-score < -2)	GR00366-A-111	9.8	MGMT
26	Decreased shRNA abundance (Z-score < -2)	GR00366-A-148	9.8	PMS2
27	Decreased shRNA abundance (Z-score < -2)	GR00366-A-153	9.8	PMS2
28	Decreased shRNA abundance (Z-score < -2)	GR00366-A-161	9.8	PMS2
29	Decreased shRNA abundance (Z-score < -2)	GR00366-A-28	9.8	PMS2
30	Decreased shRNA abundance (Z-score < -2)	GR00366-A-37	9.8	MGMT
31	Decreased shRNA abundance (Z-score < -2)	GR00366-A-56	9.8	PMS2
32	Decreased shRNA abundance (Z-score < -2)	GR00366-A-59	9.8	MGMT PMS2
33	Decreased shRNA abundance (Z-score < -2)	GR00366-A-63	9.8	PMS2
34	Decreased shRNA abundance (Z-score < -2)	GR00366-A-72	9.8	MGMT
35	Decreased shRNA abundance (Z-score < -2)	GR00366-A-98	9.8	PMS2

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Drugs & Therapeutics for Breast Giant Fibroadenoma

Search Clinical Trials , NIH Clinical Center for Breast Giant Fibroadenoma

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Genetic Tests for Breast Giant Fibroadenoma

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Anatomical Context for Breast Giant Fibroadenoma

MalaCards organs/tissues related to Breast Giant Fibroadenoma:

⁴⁰

Breast

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Publications for Breast Giant Fibroadenoma

Articles related to Breast Giant Fibroadenoma:

#	Title	Authors	PMID	Year
1	Giant fibroma of breast in an adolescent female by inverted "T" incision: A case report and literature review. ⁶¹	Tian J...Chen Q	32386049	2020
2	Surgical excision of the breast giant fibroadenoma under regional anesthesia by Pecs II and internal intercostal plane block: a case report and brief technical description: a case report. ⁶¹	Kim H...Kim I	28184271	2017
3	Giant fibroadenoma of breast in an adolescent girl. ⁶¹	Thuruthiyath N...Marla N	23071885	2012
4	An extraordinary breast giant fibroadenoma (cystosarcoma phyllodes) in a female adolescent. ⁶¹	Dong HJ...Ke RL	6097413	1984

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Genes for Breast Giant Fibroadenoma

Genes related to Breast Giant Fibroadenoma (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	PARVA	Parvin Alpha	Protein Coding	6.3	DISEASES inferred ¹⁵
2	MED12	Mediator Complex Subunit 12	Protein Coding	5.37	DISEASES inferred ¹⁵
3	TCEAL1	Transcription Elongation Factor A Like 1	Protein Coding	5.16	DISEASES inferred ¹⁵
4	PMS2	PMS1 Homolog 2, Mismatch Repair System Component	Protein Coding	4.54	DISEASES inferred ¹⁵
5	PRL	Prolactin	Protein Coding	4.47	DISEASES inferred ¹⁵
6	MGMT	O-6-Methylguanine-DNA Methyltransferase	Protein Coding	4.46	DISEASES inferred ¹⁵

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Variations for Breast Giant Fibroadenoma

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Expression for Breast Giant Fibroadenoma

Search GEO for disease gene expression data for Breast Giant Fibroadenoma.

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Pathways for Breast Giant Fibroadenoma

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GO Terms for Breast Giant Fibroadenoma

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Sources for Breast Giant Fibroadenoma

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