MCID: BRS054
MIFTS: 25

Breast Hemangioma

Categories: Cancer diseases

Aliases & Classifications for Breast Hemangioma

MalaCards integrated aliases for Breast Hemangioma:

Name: Breast Hemangioma 12 15
Angioma of the Breast 12
Haemangioma of Breast 71
Hemangioma of Breast 12

Classifications:



External Ids:

Disease Ontology 12 DOID:476
NCIt 49 C5353
UMLS 71 C0853715

Summaries for Breast Hemangioma

Disease Ontology : 12 A breast benign neoplasm that is characterized by a collection of excess blood vessels.

MalaCards based summary : Breast Hemangioma, also known as angioma of the breast, is related to capillary hemangioma and hemangioma. An important gene associated with Breast Hemangioma is CD34 (CD34 Molecule), and among its related pathways/superpathways is Cytosine methylation. Affiliated tissues include breast, and related phenotypes are hematopoietic system and homeostasis/metabolism

Related Diseases for Breast Hemangioma

Diseases related to Breast Hemangioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 181)
# Related Disease Score Top Affiliating Genes
1 capillary hemangioma 29.8 VWF PECAM1 CD34
2 hemangioma 29.2 VWF TP53 PECAM1 IDH1 CD34
3 angiosarcoma 28.8 VWF TP53 PECAM1 CD34
4 breast capillary hemangioma 11.3
5 breast epithelioid hemangioma 11.3
6 lymphangioma 10.5 PECAM1 CD34
7 glomangioma 10.5 PECAM1 CD34
8 skin epithelioid hemangioma 10.5 PECAM1 CD34
9 prostate angiosarcoma 10.5 PECAM1 CD34
10 central nervous system angiosarcoma 10.5 PECAM1 CD34
11 intravascular angioleiomyoma 10.5 PECAM1 CD34
12 heart fibrosarcoma 10.5 PECAM1 CD34
13 central nervous system hemangioma 10.5 PECAM1 CD34
14 ovarian angiosarcoma 10.5 PECAM1 CD34
15 conventional angiosarcoma 10.5 PECAM1 CD34
16 angiomyoma 10.5 PECAM1 CD34
17 aortic malignant tumor 10.5 PECAM1 CD34
18 gallbladder leiomyosarcoma 10.4 PECAM1 CD34
19 hemangioma of spleen 10.4 PECAM1 CD34
20 ovary sarcoma 10.4 PECAM1 CD34
21 heart leiomyosarcoma 10.4 PECAM1 CD34
22 colonic lymphangioma 10.4 PECAM1 CD34
23 benign perivascular tumor 10.4 PECAM1 CD34
24 liposarcoma of bone 10.4 PECAM1 CD34
25 intravascular fasciitis 10.4 PECAM1 CD34
26 retroperitoneal hemangiopericytoma 10.4 PECAM1 CD34
27 erythema elevatum diutinum 10.4 PECAM1 CD34
28 liver leiomyoma 10.4 PECAM1 CD34
29 spleen cancer 10.4 PECAM1 CD34
30 breast angiosarcoma 10.4 PECAM1 CD34
31 heart sarcoma 10.4 PECAM1 CD34
32 vulvar leiomyoma 10.4 PECAM1 CD34
33 glomeruloid hemangioma 10.4 PECAM1 CD34
34 skin sarcoma 10.4 PECAM1 CD34
35 bacillary angiomatosis 10.4 PECAM1 CD34
36 histiocytoid hemangioma 10.4 PECAM1 CD34
37 angiolipoma 10.4 PECAM1 CD34
38 benign mesenchymoma 10.4 PECAM1 CD34
39 angiokeratoma circumscriptum 10.4 PECAM1 CD34
40 pulmonary artery leiomyosarcoma 10.4 PECAM1 CD34
41 adenoid squamous cell carcinoma 10.4 PECAM1 CD34
42 subungual glomus tumor 10.4 PECAM1 CD34
43 bartonellosis 10.4 PECAM1 CD34
44 cystic lymphangioma 10.4 PECAM1 CD34
45 vulvar benign neoplasm 10.4 PECAM1 CD34
46 heart cancer 10.4 PECAM1 CD34
47 dermis tumor 10.4 PECAM1 CD34
48 papillary adenofibroma 10.3 VWF CD34
49 middle ear adenocarcinoma 10.2 VWF PECAM1
50 intussusception 10.2 PECAM1 CD34

Graphical network of the top 20 diseases related to Breast Hemangioma:



Diseases related to Breast Hemangioma

Symptoms & Phenotypes for Breast Hemangioma

MGI Mouse Phenotypes related to Breast Hemangioma:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.76 AVP CD34 F8 IDH1 PECAM1 PPP3R1
2 homeostasis/metabolism MP:0005376 9.61 AVP CD34 F8 IDH1 PECAM1 PPP3R1
3 immune system MP:0005387 9.23 AVP CD34 F8 IDH1 PECAM1 PPP3R1

Drugs & Therapeutics for Breast Hemangioma

Search Clinical Trials , NIH Clinical Center for Breast Hemangioma

Genetic Tests for Breast Hemangioma

Anatomical Context for Breast Hemangioma

MalaCards organs/tissues related to Breast Hemangioma:

40
Breast

Publications for Breast Hemangioma

Articles related to Breast Hemangioma:

(show all 23)
# Title Authors PMID Year
1
Breast hemangioma in a male patient: Report of a case. 61
30701010 2019
2
Cavernous Breast Hemangioma Mimicking an Invasive Lesion on Contrast-Enhanced MRI. 61
31093413 2019
3
Hemangioma of a Male Breast: Case Report and Review of the Literature. 61
30498190 2018
4
Cavernous Hemangioma Between the Elastomer and Fibrous Capsule of a Breast Implant. 61
29872905 2018
5
Sinusoidal hemangioma of the breast: diagnostic evaluation management and literature review. 61
28210560 2017
6
Breast hemangioma with difficulty in preoperative diagnosis: a case report. 61
25312096 2014
7
Breast Hemangioma: MR Appearance with Histopathological Correlation. 61
23029636 2012
8
Breast hemangioma investigation--a rare condition documented by nuclear medicine, radiology and pathology. 61
21492300 2011
9
A rare coexistence of concurrent breast hemangioma with fibroadenoma: a case report. 61
19829893 2009
10
Sonographic and mammographic appearances of breast hemangioma. 61
18562711 2008
11
[Recurrent breast haematoma after fine needle aspiration biopsy of angiosarcoma]. 61
17547091 2007
12
Male breast hemangioma--a rare entity: a case report and review of the literature. 61
16684325 2006
13
Radiological reasoning: male breast mass with calcifications. 61
16304041 2005
14
Breast hemangioma simulating an inflammatory carcinoma. 61
16297112 2005
15
A large benign vascular neoplasm of the male breast. A case report and review of the literature. 61
16122203 2005
16
[Breast Hemangioma]. 61
15318758 2004
17
Gadolinium-enhanced dynamic MRI of breast hemangioma. 61
14575783 2003
18
Breast hemangioma mimicking carcinoma. 61
14965696 2002
19
Hemangioma of the breast: an unusual lesion without univocal diagnostic findings. 61
11876559 2001
20
MRI of breast hemangioma. 61
9843250 1998
21
MR imaging of breast hemangioma in female infants. 61
1437377 1992
22
[Value of magnetic resonance imaging (MRI) in prognostic and therapeutic approaches of breast hemangioma in the little girl]. 61
1789668 1991
23
[Breast hemangioma; presentation of a case]. 61
13362919 1956

Variations for Breast Hemangioma

Expression for Breast Hemangioma

Search GEO for disease gene expression data for Breast Hemangioma.

Pathways for Breast Hemangioma

Pathways related to Breast Hemangioma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
9.74 IDH2 IDH1

GO Terms for Breast Hemangioma

Biological processes related to Breast Hemangioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 platelet degranulation GO:0002576 9.5 VWF PECAM1 F8
2 tricarboxylic acid cycle GO:0006099 9.46 IDH2 IDH1
3 positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway GO:1900740 9.43 TP53 PPP3R1
4 blood coagulation, intrinsic pathway GO:0007597 9.4 VWF F8
5 2-oxoglutarate metabolic process GO:0006103 9.37 IDH2 IDH1
6 NADP metabolic process GO:0006739 9.26 IDH2 IDH1
7 isocitrate metabolic process GO:0006102 9.16 IDH2 IDH1
8 glomerular endothelium development GO:0072011 8.96 PECAM1 CD34
9 glyoxylate cycle GO:0006097 8.62 IDH2 IDH1

Molecular functions related to Breast Hemangioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0016616 9.16 IDH2 IDH1
2 isocitrate dehydrogenase (NADP+) activity GO:0004450 8.96 IDH2 IDH1
3 isocitrate dehydrogenase activity GO:0004448 8.62 IDH2 IDH1

Sources for Breast Hemangioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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