MCID: BRS025
MIFTS: 28

Breast Juvenile Papillomatosis

Categories: Cancer diseases

Aliases & Classifications for Breast Juvenile Papillomatosis

MalaCards integrated aliases for Breast Juvenile Papillomatosis:

Name: Breast Juvenile Papillomatosis 12 15
Juvenile Papillomatosis of the Breast 12

Classifications:



External Ids:

Disease Ontology 12 DOID:6641
NCIt 49 C9503
UMLS 71 C1334303

Summaries for Breast Juvenile Papillomatosis

Disease Ontology : 12 A breast papillomatosis that is characterized by a discrete, muticystic breast lesion that occurs at a median age of 20 years.

MalaCards based summary : Breast Juvenile Papillomatosis, also known as juvenile papillomatosis of the breast, is related to breast papillomatosis and breast fibroadenoma. An important gene associated with Breast Juvenile Papillomatosis is OXT (Oxytocin/Neurophysin I Prepropeptide), and among its related pathways/superpathways are Chks in Checkpoint Regulation and Glioma. Affiliated tissues include breast, and related phenotypes are Decreased viability in esophageal squamous lineage and Decreased viability with cisplatin

Related Diseases for Breast Juvenile Papillomatosis

Diseases in the Breast Papillomatosis family:

Breast Juvenile Papillomatosis

Diseases related to Breast Juvenile Papillomatosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 177)
# Related Disease Score Top Affiliating Genes
1 breast papillomatosis 30.9 OXT ERBB2
2 breast fibroadenoma 28.6 PGR ESR1 ERBB2 BRCA1
3 hypertrophy of breast 28.0 PGR ESR1 ERBB2 BRCA2 BRCA1
4 lobular neoplasia 28.0 PGR ESR1 ERBB2 BRCA2 BRCA1
5 in situ carcinoma 28.0 PGR ESR1 ERBB2 BRCA2 BRCA1
6 breast disease 28.0 PGR ESR1 ERBB2 BRCA2 BRCA1
7 breast cancer 10.4
8 papilloma 10.4
9 postmenopausal atrophic vaginitis 10.1 OXT ESR1
10 scirrhous adenocarcinoma 10.1 PGR ERBB2
11 lipid-rich breast carcinoma 10.0 PGR ERBB2
12 carcinosarcoma 10.0 PGR ERBB2
13 apocrine adenosis of breast 10.0 PGR ERBB2
14 breast adenoid cystic carcinoma 10.0 PGR ERBB2
15 breast mucinous carcinoma 10.0 PGR ERBB2
16 linitis plastica 10.0 PGR ERBB2
17 bartholin's gland adenoid cystic carcinoma 10.0 PGR ESR1
18 chronic tympanitis 10.0 PGR ESR1
19 bartholin's gland adenoma 10.0 PGR ESR1
20 neurofibromatosis, type iv, of riccardi 10.0
21 noonan syndrome 1 10.0
22 squamous cell papilloma 10.0
23 pseudo-turner syndrome 10.0
24 granulomatous endometritis 10.0 PGR ESR1
25 bartholin's gland benign neoplasm 10.0 PGR ESR1
26 vestibular gland benign neoplasm 10.0 PGR ESR1
27 apocrine sweat gland neoplasm 10.0 PGR ERBB2
28 lung leiomyoma 10.0 PGR ESR1
29 vulvar syringoma 10.0 PGR ESR1
30 trigonitis 10.0 PGR ESR1
31 vagina leiomyosarcoma 10.0 PGR ESR1
32 adult type testicular granulosa cell tumor 10.0 PGR ESR1
33 ovarian seromucinous carcinoma 10.0 PGR ESR1
34 breast leiomyoma 10.0 PGR ESR1
35 gastric diffuse adenocarcinoma 10.0 PGR ERBB2
36 postpartum depression 10.0 OXT ESR1
37 intravenous leiomyomatosis 10.0 PGR ESR1
38 leiomyomatosis 10.0 PGR ESR1
39 liver leiomyoma 10.0 PGR ESR1
40 cervical adenocarcinoma 10.0 ESR1 ERBB2
41 mammographic density 10.0 PGR ESR1
42 vulvar leiomyoma 10.0 PGR ESR1
43 bizarre leiomyoma 10.0 PGR ESR1
44 vaginal endometrial stromal sarcoma 10.0 PGR ESR1
45 vulvar disease 10.0 PGR ERBB2
46 progesterone resistance 10.0 PGR ESR1
47 vagina sarcoma 10.0 PGR ESR1
48 cervical mucinous adenocarcinoma 10.0 PGR ESR1
49 adenomyoma 9.9 PGR ESR1
50 gender identity disorder 9.9 PGR ESR1

Graphical network of the top 20 diseases related to Breast Juvenile Papillomatosis:



Diseases related to Breast Juvenile Papillomatosis

Symptoms & Phenotypes for Breast Juvenile Papillomatosis

GenomeRNAi Phenotypes related to Breast Juvenile Papillomatosis according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability in esophageal squamous lineage GR00235-A 9.55 BRCA1 BRCA2 ERBB2 ESR1 PGR
2 Decreased viability with cisplatin GR00101-A-4 8.96 BRCA1 BRCA2
3 Synthetic lethal with cisplatin GR00101-A-1 8.62 BRCA1 BRCA2

MGI Mouse Phenotypes related to Breast Juvenile Papillomatosis:

45 (show all 13)
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10 BRCA1 BRCA2 ERBB2 ESR1 OXT PGR
2 endocrine/exocrine gland MP:0005379 9.93 BRCA1 BRCA2 ERBB2 ESR1 OXT PGR
3 cardiovascular system MP:0005385 9.91 BRCA1 ERBB2 ESR1 OXT PGR
4 homeostasis/metabolism MP:0005376 9.91 BRCA1 BRCA2 ERBB2 ESR1 OXT PGR
5 digestive/alimentary MP:0005381 9.89 BRCA1 BRCA2 ERBB2 ESR1 OXT
6 embryo MP:0005380 9.88 BRCA1 BRCA2 ERBB2 ESR1 PGR
7 integument MP:0010771 9.88 BRCA1 BRCA2 ERBB2 ESR1 OXT PGR
8 mortality/aging MP:0010768 9.8 BRCA1 BRCA2 ERBB2 ESR1 OXT PGR
9 limbs/digits/tail MP:0005371 9.77 BRCA1 BRCA2 ERBB2 ESR1 PGR
10 neoplasm MP:0002006 9.65 BRCA1 BRCA2 ERBB2 ESR1 PGR
11 normal MP:0002873 9.55 BRCA1 BRCA2 ERBB2 ESR1 PGR
12 reproductive system MP:0005389 9.43 BRCA1 BRCA2 ERBB2 ESR1 OXT PGR
13 skeleton MP:0005390 9.02 BRCA1 BRCA2 ERBB2 ESR1 PGR

Drugs & Therapeutics for Breast Juvenile Papillomatosis

Search Clinical Trials , NIH Clinical Center for Breast Juvenile Papillomatosis

Genetic Tests for Breast Juvenile Papillomatosis

Anatomical Context for Breast Juvenile Papillomatosis

MalaCards organs/tissues related to Breast Juvenile Papillomatosis:

40
Breast

Publications for Breast Juvenile Papillomatosis

Articles related to Breast Juvenile Papillomatosis:

(show all 26)
# Title Authors PMID Year
1
Juvenile Papillomatosis: A Case Report. 61
31001616 2019
2
Giant juvenile papillomatosis of the breast in a Nigerian girl. 61
30567257 2018
3
Juvenile Papillomatosis of the Breast in a Pre-Pubertal Girl: An Uncommon Diagnosis. 61
29322120 2018
4
Juvenile Papillomatosis (Swiss-Cheese Disease) of Breast in an Adult Male With Sequential Diagnoses of Ipsilateral Intraductal, Invasive, and Widely Metastatic Carcinoma: A Case Report and Review of the Disease in Males. 61
28420303 2017
5
Magnetic resonance imaging findings of breast juvenile papillomatosis. 61
23475601 2013
6
Juvenile papillomatosis of the breast in young male: a case report. 61
22018260 2011
7
Juvenile papillomatosis of the breast associated with neurofibromatosis 1. 61
16883593 2007
8
[Juvenille papillomatosis]. 61
16484940 2006
9
Juvenile papillomatosis of the breast in a male infant with Noonan syndrome, café au lait spots, and family history of breast carcinoma. 61
15700254 2005
10
[Juvenile papillomatosis of the breast]. 61
12870277 2003
11
Juvenile papillomatosis of the breast in a 9-year-old girl. 61
11315290 2001
12
A case of breast cancer associated with juvenile papillomatosis of the male breast. 61
11078621 2000
13
Juvenile papillomatosis of the breast in male infants: two case reports. 61
10663852 2000
14
[Breast malignancy in girls]. 61
10462972 1999
15
A Case of Multiple Juvenile Papillomatosis of the Breast and Its Immunohistochemical Pathology. 61
11091647 1998
16
Juvenile papillomatosis of the breast (Swiss cheese disease) 61
9275926 1997
17
Giant juvenile papillomatosis of the breast: report of two cases. 61
9185400 1997
18
Case report: MR imaging of juvenile papillomatosis of the breast. 61
8983594 1996
19
Juvenile papillomatosis of the breast. 61
8103370 1993
20
Juvenile papillomatosis of the breast. A multidisciplinary study. 61
2014142 1991
21
Juvenile papillomatosis of the breast. A follow-up study of 41 patients having biopsies before 1979. 61
2158224 1990
22
The continuing evolution of our understanding of juvenile papillomatosis of the breast. 61
2158228 1990
23
Juvenile papillomatosis of the breast: sonographic appearance. 61
3055027 1988
24
[Intraductal juvenile papillomatosis of the breast]. 61
3617975 1987
25
Juvenile papillomatosis of the breast and family history of breast carcinoma. 61
7074576 1982
26
Juvenile papillomatosis (Swiss cheese disease) of the breast. 61
7361994 1980

Variations for Breast Juvenile Papillomatosis

Expression for Breast Juvenile Papillomatosis

Search GEO for disease gene expression data for Breast Juvenile Papillomatosis.

Pathways for Breast Juvenile Papillomatosis

Pathways related to Breast Juvenile Papillomatosis according to GeneCards Suite gene sharing:

(show all 11)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.26 ESR1 BRCA2 BRCA1
2
Show member pathways
11.85 ESR1 ERBB2 BRCA2 BRCA1
3
Show member pathways
11.74 PGR ESR1 BRCA1
4
Show member pathways
11.69 PGR ESR1 ERBB2 BRCA2 BRCA1
5 11.62 ESR1 BRCA2 BRCA1
6
Show member pathways
11.37 PGR ESR1 ERBB2
7 11.36 ERBB2 BRCA1
8 11.28 ERBB2 BRCA1
9 11.22 ERBB2 BRCA1
10
Show member pathways
11.07 ESR1 BRCA1
11 10.94 ESR1 BRCA2

GO Terms for Breast Juvenile Papillomatosis

Cellular components related to Breast Juvenile Papillomatosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 lateral element GO:0000800 8.62 BRCA2 BRCA1

Biological processes related to Breast Juvenile Papillomatosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 double-strand break repair GO:0006302 9.37 BRCA2 BRCA1
2 response to estrogen GO:0043627 9.32 ESR1 BRCA1
3 steroid hormone mediated signaling pathway GO:0043401 9.26 PGR ESR1
4 intrinsic apoptotic signaling pathway in response to DNA damage GO:0008630 9.16 BRCA2 BRCA1
5 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator GO:0006978 8.96 BRCA2 BRCA1
6 chordate embryonic development GO:0043009 8.62 BRCA2 BRCA1

Molecular functions related to Breast Juvenile Papillomatosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 enzyme binding GO:0019899 9.43 PGR ESR1 BRCA1
2 steroid hormone receptor activity GO:0003707 9.32 PGR ESR1
3 nuclear receptor activity GO:0004879 9.16 PGR ESR1
4 identical protein binding GO:0042802 9.02 PGR ESR1 ERBB2 BRCA2 BRCA1
5 steroid binding GO:0005496 8.96 PGR ESR1

Sources for Breast Juvenile Papillomatosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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