MCID: BRS025
MIFTS: 30

Breast Juvenile Papillomatosis

Categories: Cancer diseases

Aliases & Classifications for Breast Juvenile Papillomatosis

MalaCards integrated aliases for Breast Juvenile Papillomatosis:

Name: Breast Juvenile Papillomatosis 12 15
Juvenile Papillomatosis of the Breast 12

Classifications:



External Ids:

Disease Ontology 12 DOID:6641
NCIt 49 C9503
UMLS 71 C1334303

Summaries for Breast Juvenile Papillomatosis

Disease Ontology : 12 A breast papillomatosis that is characterized by a discrete, muticystic breast lesion that occurs at a median age of 20 years.

MalaCards based summary : Breast Juvenile Papillomatosis, also known as juvenile papillomatosis of the breast, is related to breast papillomatosis and breast fibroadenoma. An important gene associated with Breast Juvenile Papillomatosis is OXT (Oxytocin/Neurophysin I Prepropeptide), and among its related pathways/superpathways are Chks in Checkpoint Regulation and Glioma. Affiliated tissues include breast, ovary and smooth muscle, and related phenotypes are Decreased viability in esophageal squamous lineage and Decreased viability with cisplatin

Related Diseases for Breast Juvenile Papillomatosis

Diseases in the Breast Papillomatosis family:

Breast Juvenile Papillomatosis

Diseases related to Breast Juvenile Papillomatosis via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 178, show less)
# Related Disease Score Top Affiliating Genes
1 breast papillomatosis 30.9 OXT ERBB2
2 breast fibroadenoma 28.6 PGR ESR1 ERBB2 BRCA1
3 hypertrophy of breast 28.0 PGR ESR1 ERBB2 BRCA2 BRCA1
4 lobular neoplasia 28.0 PGR ESR1 ERBB2 BRCA2 BRCA1
5 in situ carcinoma 28.0 PGR ESR1 ERBB2 BRCA2 BRCA1
6 breast disease 28.0 PGR ESR1 ERBB2 BRCA2 BRCA1
7 breast cancer 10.4
8 papilloma 10.4
9 postmenopausal atrophic vaginitis 10.1 OXT ESR1
10 mild pre-eclampsia 10.1 OXT ESR1
11 scirrhous adenocarcinoma 10.1 PGR ERBB2
12 lipid-rich breast carcinoma 10.0 PGR ERBB2
13 carcinosarcoma 10.0 PGR ERBB2
14 apocrine adenosis of breast 10.0 PGR ERBB2
15 breast adenoid cystic carcinoma 10.0 PGR ERBB2
16 breast mucinous carcinoma 10.0 PGR ERBB2
17 linitis plastica 10.0 PGR ERBB2
18 bartholin's gland adenoid cystic carcinoma 10.0 PGR ESR1
19 chronic tympanitis 10.0 PGR ESR1
20 bartholin's gland adenoma 10.0 PGR ESR1
21 granulomatous endometritis 10.0 PGR ESR1
22 neurofibromatosis, type iv, of riccardi 10.0
23 noonan syndrome 1 10.0
24 squamous cell papilloma 10.0
25 pseudo-turner syndrome 10.0
26 bartholin's gland benign neoplasm 10.0 PGR ESR1
27 apocrine sweat gland neoplasm 10.0 PGR ERBB2
28 vestibular gland benign neoplasm 10.0 PGR ESR1
29 lung leiomyoma 10.0 PGR ESR1
30 vulvar syringoma 10.0 PGR ESR1
31 trigonitis 10.0 PGR ESR1
32 vagina leiomyosarcoma 10.0 PGR ESR1
33 adult type testicular granulosa cell tumor 10.0 PGR ESR1
34 ovarian seromucinous carcinoma 10.0 PGR ESR1
35 breast leiomyoma 10.0 PGR ESR1
36 gastric diffuse adenocarcinoma 10.0 PGR ERBB2
37 postpartum depression 10.0 OXT ESR1
38 intravenous leiomyomatosis 10.0 PGR ESR1
39 leiomyomatosis 10.0 PGR ESR1
40 liver leiomyoma 10.0 PGR ESR1
41 cervical adenocarcinoma 10.0 ESR1 ERBB2
42 mammographic density 10.0 PGR ESR1
43 vulvar leiomyoma 10.0 PGR ESR1
44 bizarre leiomyoma 10.0 PGR ESR1
45 vulvar disease 10.0 PGR ERBB2
46 vaginal endometrial stromal sarcoma 10.0 PGR ESR1
47 vagina sarcoma 10.0 PGR ESR1
48 progesterone resistance 10.0 PGR ESR1
49 cervical mucinous adenocarcinoma 10.0 PGR ESR1
50 adenomyoma 10.0 PGR ESR1
51 gender identity disorder 9.9 PGR ESR1
52 juvenile nasopharyngeal angiofibroma 9.9 PGR ESR1
53 vulvar benign neoplasm 9.9 PGR ESR1
54 adult mesoblastic nephroma 9.9 PGR ESR1
55 vaginal cancer 9.9 PGR ESR1
56 ovarian endometrial cancer 9.9 PGR ESR1
57 estrogen excess 9.9 PGR ESR1
58 endocervical carcinoma 9.9 PGR ESR1
59 endometriosis of ovary 9.9 PGR ESR1
60 prostatic hypertrophy 9.9 PGR ESR1
61 hereditary site-specific ovarian cancer syndrome 9.9 BRCA2 BRCA1
62 rare malignant breast tumor 9.9 BRCA2 BRCA1
63 endocervical adenocarcinoma 9.9 PGR ESR1
64 oropharynx cancer 9.9 PGR ERBB2
65 tetraploidy 9.8 BRCA2 BRCA1
66 cancerophobia 9.8 BRCA2 BRCA1
67 smooth muscle tumor 9.8 PGR ESR1
68 nosophobia 9.8 BRCA2 BRCA1
69 peritoneal mesothelioma 9.8 PGR ESR1
70 uterine corpus serous adenocarcinoma 9.8 ERBB2 BRCA1
71 breast-ovarian cancer, familial 2 9.8 BRCA2 BRCA1
72 clear cell adenocarcinoma 9.8 PGR ESR1
73 breast-ovarian cancer, familial 1 9.8 BRCA2 BRCA1
74 mutagen sensitivity 9.8 BRCA2 BRCA1
75 pelvic organ prolapse 9.8 PGR ESR1
76 spindle cell carcinoma 9.8 PGR ESR1
77 dysplastic nevus syndrome 9.8 BRCA2 BRCA1
78 premature menopause 9.7 BRCA2 BRCA1
79 fallopian tube disease 9.7 BRCA2 BRCA1
80 angiomyolipoma 9.7 PGR ESR1
81 fanconi anemia, complementation group d1 9.7 BRCA2 BRCA1
82 myasthenic syndrome, congenital, 6, presynaptic 9.7 BRCA2 BRCA1
83 vaginal discharge 9.7 PGR OXT ESR1
84 endometrial disease 9.7 PGR OXT ESR1
85 fanconi anemia, complementation group j 9.7 BRCA2 BRCA1
86 endometritis 9.7 PGR OXT ESR1
87 uterine benign neoplasm 9.7 PGR OXT ESR1
88 reproductive organ benign neoplasm 9.7 PGR OXT ESR1
89 adenomyosis 9.7 PGR OXT ESR1
90 glassy cell carcinoma of the cervix 9.7 PGR ESR1 ERBB2
91 breast scirrhous carcinoma 9.7 PGR ESR1 ERBB2
92 oncocytic breast carcinoma 9.7 PGR ESR1 ERBB2
93 breast papillary carcinoma 9.7 PGR ESR1 ERBB2
94 papillary carcinoma 9.7 PGR ESR1 ERBB2
95 comedo carcinoma 9.7 PGR ESR1 ERBB2
96 myoma 9.7 PGR OXT ESR1
97 breast metaplastic carcinoma 9.7 PGR ESR1 ERBB2
98 lipid-rich carcinoma 9.7 PGR ESR1 ERBB2
99 breast malignant phyllodes tumor 9.7 PGR ESR1 ERBB2
100 progesterone-receptor negative breast cancer 9.7 PGR ESR1 ERBB2
101 breast sarcoma 9.7 PGR ESR1 ERBB2
102 apocrine adenocarcinoma 9.7 PGR ESR1 ERBB2
103 breast osteosarcoma 9.7 PGR ESR1 ERBB2
104 cribriform carcinoma 9.7 PGR ESR1 ERBB2
105 intraductal breast neoplasm 9.7 PGR ESR1 ERBB2
106 breast neuroendocrine neoplasm 9.7 PGR ESR1 ERBB2
107 progesterone-receptor positive breast cancer 9.7 PGR ESR1 ERBB2
108 intraductal papilloma 9.7 PGR ESR1 ERBB2
109 microglandular adenosis 9.7 PGR ESR1 ERBB2
110 adenosarcoma 9.7 PGR ESR1 ERBB2
111 inflammatory breast carcinoma 9.7 PGR ESR1 ERBB2
112 sweat gland disease 9.7 PGR ESR1 ERBB2
113 sweat gland cancer 9.7 PGR ESR1 ERBB2
114 mixed cell type cancer 9.7 PGR ESR1 ERBB2
115 tonsil cancer 9.7 PGR ESR1 ERBB2
116 leiomyoma, uterine 9.7 PGR OXT ESR1
117 tubular adenocarcinoma 9.7 PGR ESR1 ERBB2
118 large cell neuroendocrine carcinoma 9.7 PGR ESR1 ERBB2
119 mammary paget's disease 9.7 PGR ESR1 ERBB2
120 primary pigmented nodular adrenocortical disease 9.7 PGR ESR1
121 amelogenesis imperfecta, type ig 9.7 PGR ESR1 ERBB2
122 migraine with or without aura 1 9.7 OXT ESR1 BRCA2
123 amelogenesis imperfecta 9.7 PGR ESR1 ERBB2
124 teeth hard tissue disease 9.7 PGR ESR1 ERBB2
125 mucinous adenocarcinoma 9.7 PGR ESR1 ERBB2
126 gynecomastia 9.7 PGR ESR1 ERBB2
127 endometrial adenocarcinoma 9.7 PGR ESR1 ERBB2
128 uterine carcinosarcoma 9.6 PGR ESR1 ERBB2
129 dysgerminoma 9.6 BRCA2 BRCA1
130 meningioma, familial 9.6 PGR ESR1 ERBB2
131 breast adenocarcinoma 9.6 PGR ESR1 ERBB2
132 carpal tunnel syndrome 9.5 PGR ESR1
133 peritoneum cancer 9.5 ERBB2 BRCA2 BRCA1
134 ovarian cystadenocarcinoma 9.5 ERBB2 BRCA2 BRCA1
135 familial ovarian cancer 9.5 ESR1 BRCA2 BRCA1
136 cowden syndrome 9.5 ERBB2 BRCA2 BRCA1
137 cystadenoma 9.5 PGR BRCA1
138 congenital hypoplastic anemia 9.5 BRCA2 BRCA1
139 adenoid cystic carcinoma 9.4 PGR ERBB2 BRCA1
140 synchronous bilateral breast carcinoma 9.4 PGR BRCA2 BRCA1
141 autosomal genetic disease 9.4 ESR1 BRCA2 BRCA1
142 papillary serous adenocarcinoma 9.4 PGR BRCA2 BRCA1
143 endometrial hyperplasia 9.4 PGR ESR1
144 wilms tumor 1 9.3 PGR ESR1 ERBB2 BRCA2
145 li-fraumeni syndrome 9.1 ESR1 ERBB2 BRCA2 BRCA1
146 suppression of tumorigenicity 12 9.1 ESR1 ERBB2 BRCA2 BRCA1
147 rare breast tumor 9.1 ESR1 ERBB2 BRCA2 BRCA1
148 pancreatic adenocarcinoma 9.1 ESR1 ERBB2 BRCA2 BRCA1
149 primary peritoneal carcinoma 9.1 PGR ERBB2 BRCA2 BRCA1
150 papillary adenocarcinoma 9.1 PGR ERBB2 BRCA2 BRCA1
151 luminal breast carcinoma 9.1 PGR ESR1 ERBB2 BRCA1
152 estrogen-receptor negative breast cancer 9.1 PGR ESR1 ERBB2 BRCA1
153 serous cystadenocarcinoma 9.1 PGR ERBB2 BRCA2 BRCA1
154 estrogen-receptor positive breast cancer 9.1 PGR ESR1 ERBB2 BRCA1
155 ovarian serous cystadenocarcinoma 9.1 PGR ERBB2 BRCA2 BRCA1
156 glioblastoma multiforme 9.1 ESR1 ERBB2 BRCA2 BRCA1
157 thoracic cancer 9.1 PGR ESR1 ERBB2 BRCA1
158 leukemia, acute myeloid 9.0 ESR1 ERBB2 BRCA2 BRCA1
159 endosalpingiosis 9.0 PGR ESR1 BRCA2 BRCA1
160 intracystic papillary adenoma 8.7 PGR ESR1 ERBB2 BRCA2 BRCA1
161 female reproductive endometrioid cancer 8.7 PGR ESR1 ERBB2 BRCA2 BRCA1
162 thoracic benign neoplasm 8.7 PGR ESR1 ERBB2 BRCA2 BRCA1
163 breast benign neoplasm 8.7 PGR ESR1 ERBB2 BRCA2 BRCA1
164 bilateral breast cancer 8.7 PGR ESR1 ERBB2 BRCA2 BRCA1
165 uterine corpus cancer 8.7 PGR ESR1 ERBB2 BRCA2 BRCA1
166 fallopian tube carcinoma 8.7 PGR ESR1 ERBB2 BRCA2 BRCA1
167 female breast cancer 8.7 PGR ESR1 ERBB2 BRCA2 BRCA1
168 pre-malignant neoplasm 8.7 PGR ESR1 ERBB2 BRCA2 BRCA1
169 sporadic breast cancer 8.7 PGR ESR1 ERBB2 BRCA2 BRCA1
170 ovary adenocarcinoma 8.7 PGR ESR1 ERBB2 BRCA2 BRCA1
171 breast carcinoma in situ 8.7 PGR ESR1 ERBB2 BRCA2 BRCA1
172 ductal carcinoma in situ 8.7 PGR ESR1 ERBB2 BRCA2 BRCA1
173 malignant ovarian surface epithelial-stromal neoplasm 8.7 PGR ESR1 ERBB2 BRCA2 BRCA1
174 ovary epithelial cancer 8.7 PGR ESR1 ERBB2 BRCA2 BRCA1
175 breast ductal carcinoma 8.7 PGR ESR1 ERBB2 BRCA2 BRCA1
176 ovarian disease 8.7 PGR ESR1 ERBB2 BRCA2 BRCA1
177 ovarian cancer 8.7 PGR ESR1 ERBB2 BRCA2 BRCA1
178 endometrial cancer 8.6 PGR ESR1 ERBB2 BRCA2 BRCA1

Graphical network of the top 20 diseases related to Breast Juvenile Papillomatosis:



Diseases related to Breast Juvenile Papillomatosis

Symptoms & Phenotypes for Breast Juvenile Papillomatosis

GenomeRNAi Phenotypes related to Breast Juvenile Papillomatosis according to GeneCards Suite gene sharing:

26 (showing 3, show less)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability in esophageal squamous lineage GR00235-A 9.55 BRCA1 BRCA2 ERBB2 ESR1 PGR
2 Decreased viability with cisplatin GR00101-A-4 8.96 BRCA1 BRCA2
3 Synthetic lethal with cisplatin GR00101-A-1 8.62 BRCA1 BRCA2

MGI Mouse Phenotypes related to Breast Juvenile Papillomatosis:

45 (showing 13, show less)
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10 BRCA1 BRCA2 ERBB2 ESR1 OXT PGR
2 endocrine/exocrine gland MP:0005379 9.93 BRCA1 BRCA2 ERBB2 ESR1 OXT PGR
3 cardiovascular system MP:0005385 9.91 BRCA1 ERBB2 ESR1 OXT PGR
4 homeostasis/metabolism MP:0005376 9.91 BRCA1 BRCA2 ERBB2 ESR1 OXT PGR
5 digestive/alimentary MP:0005381 9.89 BRCA1 BRCA2 ERBB2 ESR1 OXT
6 embryo MP:0005380 9.88 BRCA1 BRCA2 ERBB2 ESR1 PGR
7 integument MP:0010771 9.88 BRCA1 BRCA2 ERBB2 ESR1 OXT PGR
8 mortality/aging MP:0010768 9.8 BRCA1 BRCA2 ERBB2 ESR1 OXT PGR
9 limbs/digits/tail MP:0005371 9.77 BRCA1 BRCA2 ERBB2 ESR1 PGR
10 neoplasm MP:0002006 9.65 BRCA1 BRCA2 ERBB2 ESR1 PGR
11 normal MP:0002873 9.55 BRCA1 BRCA2 ERBB2 ESR1 PGR
12 reproductive system MP:0005389 9.43 BRCA1 BRCA2 ERBB2 ESR1 OXT PGR
13 skeleton MP:0005390 9.02 BRCA1 BRCA2 ERBB2 ESR1 PGR

Drugs & Therapeutics for Breast Juvenile Papillomatosis

Search Clinical Trials , NIH Clinical Center for Breast Juvenile Papillomatosis

Genetic Tests for Breast Juvenile Papillomatosis

Anatomical Context for Breast Juvenile Papillomatosis

MalaCards organs/tissues related to Breast Juvenile Papillomatosis:

40
Breast, Ovary, Smooth Muscle, Liver, Lung, Prostate, Cervix

Publications for Breast Juvenile Papillomatosis

Articles related to Breast Juvenile Papillomatosis:

(showing 26, show less)
# Title Authors PMID Year
1
Juvenile Papillomatosis: A Case Report. 61
31001616 2019
2
Giant juvenile papillomatosis of the breast in a Nigerian girl. 61
30567257 2018
3
Juvenile Papillomatosis of the Breast in a Pre-Pubertal Girl: An Uncommon Diagnosis. 61
29322120 2018
4
Juvenile Papillomatosis (Swiss-Cheese Disease) of Breast in an Adult Male With Sequential Diagnoses of Ipsilateral Intraductal, Invasive, and Widely Metastatic Carcinoma: A Case Report and Review of the Disease in Males. 61
28420303 2017
5
Magnetic resonance imaging findings of breast juvenile papillomatosis. 61
23475601 2013
6
Juvenile papillomatosis of the breast in young male: a case report. 61
22018260 2011
7
Juvenile papillomatosis of the breast associated with neurofibromatosis 1. 61
16883593 2007
8
[Juvenille papillomatosis]. 61
16484940 2006
9
Juvenile papillomatosis of the breast in a male infant with Noonan syndrome, café au lait spots, and family history of breast carcinoma. 61
15700254 2005
10
[Juvenile papillomatosis of the breast]. 61
12870277 2003
11
Juvenile papillomatosis of the breast in a 9-year-old girl. 61
11315290 2001
12
A case of breast cancer associated with juvenile papillomatosis of the male breast. 61
11078621 2000
13
Juvenile papillomatosis of the breast in male infants: two case reports. 61
10663852 2000
14
[Breast malignancy in girls]. 61
10462972 1999
15
A Case of Multiple Juvenile Papillomatosis of the Breast and Its Immunohistochemical Pathology. 61
11091647 1998
16
Juvenile papillomatosis of the breast (Swiss cheese disease) 61
9275926 1997
17
Giant juvenile papillomatosis of the breast: report of two cases. 61
9185400 1997
18
Case report: MR imaging of juvenile papillomatosis of the breast. 61
8983594 1996
19
Juvenile papillomatosis of the breast. 61
8103370 1993
20
Juvenile papillomatosis of the breast. A multidisciplinary study. 61
2014142 1991
21
Juvenile papillomatosis of the breast. A follow-up study of 41 patients having biopsies before 1979. 61
2158224 1990
22
The continuing evolution of our understanding of juvenile papillomatosis of the breast. 61
2158228 1990
23
Juvenile papillomatosis of the breast: sonographic appearance. 61
3055027 1988
24
[Intraductal juvenile papillomatosis of the breast]. 61
3617975 1987
25
Juvenile papillomatosis of the breast and family history of breast carcinoma. 61
7074576 1982
26
Juvenile papillomatosis (Swiss cheese disease) of the breast. 61
7361994 1980

Variations for Breast Juvenile Papillomatosis

Expression for Breast Juvenile Papillomatosis

Search GEO for disease gene expression data for Breast Juvenile Papillomatosis.

Pathways for Breast Juvenile Papillomatosis

Pathways related to Breast Juvenile Papillomatosis according to GeneCards Suite gene sharing:

(showing 11, show less)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.26 ESR1 BRCA2 BRCA1
2
Show member pathways
11.85 ESR1 ERBB2 BRCA2 BRCA1
3
Show member pathways
11.74 PGR ESR1 BRCA1
4
Show member pathways
11.69 PGR ESR1 ERBB2 BRCA2 BRCA1
5 11.62 ESR1 BRCA2 BRCA1
6
Show member pathways
11.37 PGR ESR1 ERBB2
7 11.36 ERBB2 BRCA1
8 11.28 ERBB2 BRCA1
9 11.22 ERBB2 BRCA1
10
Show member pathways
11.07 ESR1 BRCA1
11 10.94 ESR1 BRCA2

GO Terms for Breast Juvenile Papillomatosis

Cellular components related to Breast Juvenile Papillomatosis according to GeneCards Suite gene sharing:

(showing 1, show less)
# Name GO ID Score Top Affiliating Genes
1 lateral element GO:0000800 8.62 BRCA2 BRCA1

Biological processes related to Breast Juvenile Papillomatosis according to GeneCards Suite gene sharing:

(showing 6, show less)
# Name GO ID Score Top Affiliating Genes
1 double-strand break repair GO:0006302 9.37 BRCA2 BRCA1
2 response to estrogen GO:0043627 9.32 ESR1 BRCA1
3 steroid hormone mediated signaling pathway GO:0043401 9.26 PGR ESR1
4 intrinsic apoptotic signaling pathway in response to DNA damage GO:0008630 9.16 BRCA2 BRCA1
5 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator GO:0006978 8.96 BRCA2 BRCA1
6 chordate embryonic development GO:0043009 8.62 BRCA2 BRCA1

Molecular functions related to Breast Juvenile Papillomatosis according to GeneCards Suite gene sharing:

(showing 5, show less)
# Name GO ID Score Top Affiliating Genes
1 enzyme binding GO:0019899 9.43 PGR ESR1 BRCA1
2 steroid hormone receptor activity GO:0003707 9.32 PGR ESR1
3 nuclear receptor activity GO:0004879 9.16 PGR ESR1
4 identical protein binding GO:0042802 9.02 PGR ESR1 ERBB2 BRCA2 BRCA1
5 steroid binding GO:0005496 8.96 PGR ESR1

Sources for Breast Juvenile Papillomatosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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