MCID: BRS018
MIFTS: 21

Breast Leiomyoma

Categories: Cancer diseases

Aliases & Classifications for Breast Leiomyoma

MalaCards integrated aliases for Breast Leiomyoma:

Name: Breast Leiomyoma 12 15 71

Classifications:



External Ids:

Disease Ontology 12 DOID:1623
NCIt 49 C40399
UMLS 71 C1511317

Summaries for Breast Leiomyoma

Disease Ontology : 12 A breast benign neoplasm that has material basis in smooth muscle cells.

MalaCards based summary : Breast Leiomyoma is related to leiomyosarcoma and leiomyoma. An important gene associated with Breast Leiomyoma is FIG4 (FIG4 Phosphoinositide 5-Phosphatase), and among its related pathways/superpathways is B Cell Development Pathways. Affiliated tissues include breast, smooth muscle and skin.

Related Diseases for Breast Leiomyoma

Diseases related to Breast Leiomyoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 168)
# Related Disease Score Top Affiliating Genes
1 leiomyosarcoma 29.3 PGR FH ESR1
2 leiomyoma 28.3 PGR MME FH ESR1 CD34
3 dartoic leiomyoma 10.3 FH CLEC2A
4 cutaneous leiomyosarcoma 10.3 FH CLEC2A
5 leiomyoma cutis 10.3 FH CLEC2A
6 myiasis 10.2 HECTD4 CLEC2A
7 syringoma 10.2 ESR1 CLEC2A
8 birt-hogg-dube syndrome 10.2 FH CLEC2A
9 eccrine sweat gland neoplasm 10.2 MME CLEC2A
10 hidradenoma 10.1 MME CLEC2A
11 diffuse peritoneal leiomyomatosis 10.1 PGR FH
12 kidney benign neoplasm 10.1 MME FH
13 peritoneal benign neoplasm 10.1 PGR FH
14 apocrine sweat gland neoplasm 10.1 PGR CLEC2A
15 wolffian duct adenocarcinoma 10.1 MME ESR1
16 endometrial clear cell adenocarcinoma 10.1 MME ESR1
17 spondylolisthesis 10.1 HECTD4 ESR1
18 mucinous adenocarcinoma 10.0 PGR ESR1
19 cervical adenomyoma 10.0 PGR MME
20 glassy cell carcinoma of the cervix 10.0 PGR ESR1
21 bartholin's gland adenoid cystic carcinoma 10.0 PGR ESR1
22 chronic tympanitis 10.0 PGR ESR1
23 bartholin's gland adenoma 10.0 PGR ESR1
24 granulomatous endometritis 10.0 PGR ESR1
25 endometritis 10.0 PGR ESR1
26 bartholin's gland benign neoplasm 10.0 PGR ESR1
27 vestibular gland benign neoplasm 10.0 PGR ESR1
28 breast juvenile papillomatosis 10.0 PGR ESR1
29 lung leiomyoma 10.0 PGR ESR1
30 vulvar syringoma 10.0 PGR ESR1
31 trigonitis 10.0 PGR ESR1
32 breast scirrhous carcinoma 10.0 PGR ESR1
33 cervical serous adenocarcinoma 10.0 PGR MME
34 oncocytic breast carcinoma 10.0 PGR ESR1
35 vagina leiomyosarcoma 10.0 PGR ESR1
36 adult type testicular granulosa cell tumor 10.0 PGR ESR1
37 ovarian seromucinous carcinoma 10.0 PGR ESR1
38 breast papillary carcinoma 10.0 PGR ESR1
39 comedo carcinoma 10.0 PGR ESR1
40 breast metaplastic carcinoma 10.0 PGR ESR1
41 mammographic density 10.0 PGR ESR1
42 lipid-rich carcinoma 10.0 PGR ESR1
43 pancreatic mucinous cystadenoma 10.0 PGR MME
44 cystadenoma 10.0 PGR MME
45 clear cell adenocarcinoma 10.0 PGR ESR1
46 endosalpingiosis 10.0 PGR ESR1
47 progesterone-receptor negative breast cancer 10.0 PGR ESR1
48 cutaneous adenocystic carcinoma 10.0 PGR MME
49 progesterone resistance 10.0 PGR ESR1
50 apocrine adenocarcinoma 10.0 PGR ESR1

Graphical network of the top 20 diseases related to Breast Leiomyoma:



Diseases related to Breast Leiomyoma

Symptoms & Phenotypes for Breast Leiomyoma

Drugs & Therapeutics for Breast Leiomyoma

Search Clinical Trials , NIH Clinical Center for Breast Leiomyoma

Genetic Tests for Breast Leiomyoma

Anatomical Context for Breast Leiomyoma

MalaCards organs/tissues related to Breast Leiomyoma:

40
Breast, Smooth Muscle, Skin, Lung, Prostate, Kidney, Liver

Publications for Breast Leiomyoma

Articles related to Breast Leiomyoma:

# Title Authors PMID Year
1
Leiomyoma of the breast parenchyma: a case report and review of the literature. 61
28977094 2018
2
Nipple inversion caused by a breast leiomyoma. 61
22616738 2012
3
Breast leiomyoma. 61
9770947 1998
4
Parenchymal leiomyoma of the breast. Report of a case and clinicopathological review. 61
7851564 1995

Variations for Breast Leiomyoma

Expression for Breast Leiomyoma

Search GEO for disease gene expression data for Breast Leiomyoma.

Pathways for Breast Leiomyoma

Pathways related to Breast Leiomyoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.35 MME CD34

GO Terms for Breast Leiomyoma

Biological processes related to Breast Leiomyoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 steroid hormone mediated signaling pathway GO:0043401 9.16 PGR ESR1
2 negative regulation of gene expression GO:0010629 9.13 PGR ESR1 CD34
3 paracrine signaling GO:0038001 8.62 PGR CD34

Molecular functions related to Breast Leiomyoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 steroid hormone receptor activity GO:0003707 9.16 PGR ESR1
2 nuclear receptor activity GO:0004879 8.96 PGR ESR1
3 steroid binding GO:0005496 8.62 PGR ESR1

Sources for Breast Leiomyoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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