MCID: BRS001
MIFTS: 37

Breast Lymphoma

Categories: Cancer diseases, Immune diseases

Aliases & Classifications for Breast Lymphoma

MalaCards integrated aliases for Breast Lymphoma:

Name: Breast Lymphoma 12 15 73
Malignant Lymphoma of Breast 12
Lymphoma of the Breast 12
Lymphoma of Breast 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5826

Summaries for Breast Lymphoma

Disease Ontology : 12 A breast cancer that arises_from lymphocytes.

MalaCards based summary : Breast Lymphoma, also known as malignant lymphoma of breast, is related to intravascular large b-cell lymphoma and marginal zone b-cell lymphoma. An important gene associated with Breast Lymphoma is PIBF1 (Progesterone Immunomodulatory Binding Factor 1), and among its related pathways/superpathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers and B Cell Development Pathways. The drugs rituximab and Immunologic Factors have been mentioned in the context of this disorder. Affiliated tissues include breast, bone and b cells.

Related Diseases for Breast Lymphoma

Diseases related to Breast Lymphoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 64)
# Related Disease Score Top Affiliating Genes
1 intravascular large b-cell lymphoma 29.8 BCL6 CD5
2 marginal zone b-cell lymphoma 29.6 BCL6 CD5 CD79A
3 cryoglobulinemia 29.3 CD5 CD79A
4 lymphoblastic lymphoma 29.3 BCL6 CD5
5 peripheral t-cell lymphoma 29.2 BCL6 CD5
6 b-cell lymphomas 29.2 BCL6 CD5
7 mantle cell lymphoma 29.2 BCL6 CD5
8 diffuse large b-cell lymphoma 29.1 BCL6 CD5 CD79A
9 lymphosarcoma 29.0 BCL6 CD5 CD79A SMUG1
10 lymphoma, hodgkin, classic 28.8 BCL6 CD5 CD79A SMUG1
11 lymphoma, mucosa-associated lymphoid type 28.8 BCL6 CD5 CD79A SMUG1
12 lymphoma, non-hodgkin, familial 28.8 BCL6 CD5 CD79A SMUG1
13 lymphoma 10.7
14 bone lymphoma 10.1 BCL6 SMUG1
15 central nervous system hematologic cancer 10.0 BCL6 SMUG1
16 mediastinal malignant lymphoma 10.0 BCL6 CD79A
17 mature b-cell neoplasm 10.0 BCL6 CD79A
18 pediatric lymphoma 10.0 CD79A SMUG1
19 composite lymphoma 9.9 BCL6 CD5
20 nodal marginal zone lymphoma 9.9
21 amyloidosis 9.9
22 epidural neoplasm 9.9 BCL6 CD5
23 autoimmune lymphoproliferative syndrome, type v 9.9 BCL6 CD5
24 intestinal disease 9.9 BCL6 SMUG1
25 prostate lymphoma 9.9 CD5 SMUG1
26 bladder lymphoma 9.9 CD5 CD79A
27 splenic marginal zone lymphoma 9.9 BCL6 CD5
28 adult lymphoma 9.9 CD5 SMUG1
29 thymus gland disease 9.9 CD5 SMUG1
30 eye lymphoma 9.9 CD5 CFAP298
31 breast cancer 9.9
32 lymphatic system disease 9.9 CD5 SMUG1
33 burkitt lymphoma 9.8
34 thymus cancer 9.8 CD5 SMUG1
35 anaplastic large cell lymphoma 9.8
36 alk-negative anaplastic large cell lymphoma 9.8
37 rheumatoid arthritis 9.8
38 arthritis 9.8
39 mastitis 9.8
40 gynecomastia 9.8
41 colon lymphoma 9.8 BCL6 CD5 CD79A
42 ductal carcinoma in situ 9.7
43 breast abscess 9.7
44 panniculitis 9.7
45 hairy cell leukemia 9.7
46 inflammatory breast carcinoma 9.7
47 bilateral breast cancer 9.7
48 in situ carcinoma 9.7
49 viral infectious disease 9.7
50 al amyloidosis 9.7

Graphical network of the top 20 diseases related to Breast Lymphoma:



Diseases related to Breast Lymphoma

Symptoms & Phenotypes for Breast Lymphoma

Drugs & Therapeutics for Breast Lymphoma

Drugs for Breast Lymphoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
rituximab Approved 174722-31-7 10201696
2 Immunologic Factors
3 Antirheumatic Agents

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 This Trial is a Prospective Observational Study of Newly Diagnosed Diffuse Large B Cell Primary Breast Lymphomas Terminated NCT01279772
2 Observational Study of Diffuse Large B Cell Primary Breast Lymphomas Treated With RCHOP +/- XRT Terminated NCT01144754 Rituximab

Search NIH Clinical Center for Breast Lymphoma

Genetic Tests for Breast Lymphoma

Anatomical Context for Breast Lymphoma

MalaCards organs/tissues related to Breast Lymphoma:

41
Breast, Bone, B Cells, Bone Marrow, Lung, T Cells, Thymus

Publications for Breast Lymphoma

Articles related to Breast Lymphoma:

(show top 50) (show all 146)
# Title Authors Year
1
Management and outcomes of women diagnosed with primary breast lymphoma: a multi-institution experience. ( 29356916 )
2018
2
Breast lymphoma occurring after an invasive ductal breast carcinoma developed in the same area: A case report and literature review. ( 29657120 )
2018
3
Primary Breast Lymphoma-Population-Level Insights into an Infrequent but Increasingly Recognized Subtype of Lymphoma. ( 28376146 )
2017
4
Diffuse Large B-Cell Breast Lymphoma: A Case Series. ( 28839450 )
2017
5
Breast lymphoma in a patient with B-cell Non Hodgkin Lymphoma: A case report study. ( 28915427 )
2017
6
Primary Breast Lymphoma in the United States: 1975-2013. ( 28376147 )
2017
7
Primary Breast Lymphoma: A Case Report and Review of the Literature. ( 28839526 )
2017
8
Primary Breast Lymphoma with cutaneous involvement in a patient with Rheumatoid Arthritis - a complication of infliximab therapy? ( 28375194 )
2017
9
Role of core needle biopsy in primary breast lymphoma. ( 28510806 )
2017
10
Primary breast lymphoma: A single center study. ( 28356993 )
2017
11
Primary breast lymphoma: a case report. ( 28270358 )
2017
12
Breast Lymphoma Treatment Outcomes in a Pakistani Population: 20 Years of Experience at a Single Center. ( 27510022 )
2016
13
Primary Breast Lymphoma in a Woman: A Case Report and Review of the Literature. ( 26893404 )
2016
14
Primary Breast Lymphoma: Analysis of 55 Cases of the Spanish Lymphoma Oncology Group. ( 27847267 )
2016
15
Radiation therapy for primary breast lymphoma in male gynecomastia: a rare case report and review of the literature. ( 27225235 )
2016
16
Sonoelastography of Breast Lymphoma. ( 26808169 )
2016
17
Clinicopathological features of thirty patients with primary breast lymphoma and review of the literature. ( 25572809 )
2015
18
First pathological study of canine primary breast lymphoma and the description of its clinicopathological characteristics as an animal model for human primary breast lymphoma. ( 25469251 )
2015
19
Primary breast lymphoma presenting as non-healing axillary abscess. ( 26446318 )
2015
20
F-18 FDG PET/MRI findings of primary breast lymphoma in two cases: FDG PET/MRI findings of primary breast lymphoma. ( 25748090 )
2015
21
MRI features of breast lymphoma: preliminary experience in seven cases. ( 26380896 )
2015
22
Report of a case of primary breast lymphoma highlighting the importance of fine needle aspiration cytology as an initial diagnostic tool. ( 26229252 )
2015
23
Primary breast lymphoma with progression to the scalp. ( 26458702 )
2015
24
Primary breast lymphoma. ( 24953564 )
2014
25
Primary breast lymphoma: 30 years of experience with diagnosis and treatment at a single medical center. ( 24257833 )
2014
26
Breast lymphoma combined with postoperative acute hematopoietic disorder in an immediate breast reconstruction patient. ( 24491455 )
2014
27
Isolated cerebellar hypermetabolism on FDG PET in a case of remitted primary breast lymphoma. ( 24591788 )
2014
28
Primary breast lymphoma: A single-institute experience in Taiwan. ( 25179707 )
2014
29
Synchronous breast cancer and breast lymphoma: two case reports and literature review. ( 25035665 )
2014
30
The features of breast lymphoma on MRI. ( 24029630 )
2013
31
Unusual breast neoplasm: primary breast lymphoma. ( 23749857 )
2013
32
MR imaging of malignant primary breast lymphoma: including diffusion-weighted imaging, histologic features, and a literature review. ( 23846235 )
2013
33
Cytodiagnosis of the primary breast lymphoma in a young woman. ( 24648678 )
2013
34
Primary breast lymphoma. ( 23906238 )
2013
35
Bilateral primary breast lymphoma in a teenage girl with multi-organ involvement. ( 24026996 )
2013
36
Primary breast lymphoma: a single institution's experience. ( 23646311 )
2013
37
Primary breast lymphoma in males-a report of two cases with a review of the literature. ( 24723970 )
2013
38
Primary diffuse large B-cell lymphoma of the nipple: a rare case of breast lymphoma localized in the nipple. ( 23316783 )
2013
39
Breast lymphoma presenting as gynecomastia in male patient. ( 23815269 )
2013
40
Three Cases of Combined Therapy in Primary Breast Lymphoma (PBL) with Successful Outcomes. ( 23885182 )
2013
41
Primary and secondary breast lymphoma: prevalence, clinical signs and radiological features. ( 22665932 )
2012
42
Synchronous bilateral primary breast lymphoma. ( 22616682 )
2012
43
Primary breast lymphoma sequentially relapsed in the peripheral and central nervous system. ( 22426680 )
2012
44
Treatment and outcomes of primary breast lymphoma. ( 23018097 )
2012
45
Fusion PET-CT detection of neurolymphomatosis originating from primary breast lymphoma: A case report and literature review. ( 23162634 )
2012
46
Infiltrating ductal carcinoma of the breast associated with primary breast lymphoma. ( 21475637 )
2011
47
Breast lymphoma complicating anti-tumor necrosis factor therapy in rheumatoid arthritis. ( 21729669 )
2011
48
Analysis of 31 cases of primary breast lymphoma: the effect of nodal involvement and microvascular density. ( 21454188 )
2011
49
Primary breast lymphoma with sudden death. ( 21512383 )
2011
50
Primary breast lymphoma clinically mimicking acute mastitis: a case report. ( 21617722 )
2011

Variations for Breast Lymphoma

Expression for Breast Lymphoma

Search GEO for disease gene expression data for Breast Lymphoma.

Pathways for Breast Lymphoma

Pathways related to Breast Lymphoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.02 CD5 CD79A
2 10.35 BCL6 CD5

GO Terms for Breast Lymphoma

Biological processes related to Breast Lymphoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 immune system process GO:0002376 9.13 BCL6 CD79A PIBF1
2 B cell differentiation GO:0030183 8.62 BCL6 CD79A

Sources for Breast Lymphoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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