MCID: BRS001
MIFTS: 33

Breast Lymphoma

Categories: Cancer diseases, Immune diseases

Aliases & Classifications for Breast Lymphoma

MalaCards integrated aliases for Breast Lymphoma:

Name: Breast Lymphoma 12 15 74
Malignant Lymphoma of Breast 12
Lymphoma of the Breast 12
Lymphoma of Breast 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5826

Summaries for Breast Lymphoma

Disease Ontology : 12 A breast cancer that arises_from lymphocytes.

MalaCards based summary : Breast Lymphoma, also known as malignant lymphoma of breast, is related to intravascular large b-cell lymphoma and marginal zone b-cell lymphoma. An important gene associated with Breast Lymphoma is PIBF1 (Progesterone Immunomodulatory Binding Factor 1), and among its related pathways/superpathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers and B Cell Development Pathways. The drugs rituximab and Antineoplastic Agents, Immunological have been mentioned in the context of this disorder. Affiliated tissues include breast, b cells and bone.

Related Diseases for Breast Lymphoma

Diseases related to Breast Lymphoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 73)
# Related Disease Score Top Affiliating Genes
1 intravascular large b-cell lymphoma 30.0 BCL6 CD5
2 marginal zone b-cell lymphoma 29.4 BCL6 CD5 CD79A
3 lymphoblastic lymphoma 29.4 BCL6 CD5
4 cryoglobulinemia 29.2 CD5 CD79A
5 peripheral t-cell lymphoma 29.1 ALK BCL6 CD5
6 mantle cell lymphoma 29.0 BCL6 CD5
7 diffuse large b-cell lymphoma 28.8 BCL6 CD5 CD79A
8 lymphosarcoma 28.6 BCL6 CD5 CD79A SMUG1
9 lymphoma, mucosa-associated lymphoid type 28.4 BCL6 CD5 CD79A SMUG1
10 lymphoma, hodgkin, classic 27.9 ALK BCL6 CD5 CD79A SMUG1
11 lymphoma, non-hodgkin, familial 27.9 ALK BCL6 CD5 CD79A SMUG1
12 lymphoma 10.7
13 bone lymphoma 10.1 BCL6 SMUG1
14 central nervous system hematologic cancer 10.1 BCL6 SMUG1
15 composite lymphoma 10.0 BCL6 CD5
16 lemierre's syndrome 10.0 ALK SMUG1
17 reticulosarcoma 10.0 ALK BCL6
18 epidural neoplasm 10.0 BCL6 CD5
19 in situ pulmonary adenocarcinoma 10.0 ALK SMUG1
20 prostate lymphoma 10.0 CD5 SMUG1
21 splenic marginal zone lymphoma 10.0 BCL6 CD5
22 nodal marginal zone lymphoma 10.0
23 amyloidosis 10.0
24 thymus gland disease 9.9 CD5 SMUG1
25 breast cancer 9.9
26 lymphatic system disease 9.9 CD5 SMUG1
27 intestinal disease 9.9 BCL6 SMUG1
28 respiratory system cancer 9.9 ALK SMUG1
29 mediastinal malignant lymphoma 9.9 BCL6 CD79A
30 hodgkin's lymphoma, lymphocytic depletion 9.9 ALK CD79A
31 burkitt lymphoma 9.9
32 thymus cancer 9.9 CD5 SMUG1
33 mature b-cell neoplasm 9.8 BCL6 CD79A
34 anaplastic large cell lymphoma 9.8
35 alk-negative anaplastic large cell lymphoma 9.8
36 bladder lymphoma 9.8 CD5 CD79A
37 rheumatoid arthritis 9.8
38 arthritis 9.8
39 b-cell lymphomas 9.8
40 mastitis 9.8
41 gynecomastia 9.8
42 respiratory system disease 9.8 ALK SMUG1
43 autoimmune lymphoproliferative syndrome, type v 9.7 ALK BCL6 CD5
44 leukemia 9.7
45 ductal carcinoma in situ 9.7
46 breast abscess 9.7
47 panniculitis 9.7
48 hairy cell leukemia 9.7
49 bilateral breast cancer 9.7
50 in situ carcinoma 9.7

Graphical network of the top 20 diseases related to Breast Lymphoma:



Diseases related to Breast Lymphoma

Symptoms & Phenotypes for Breast Lymphoma

Drugs & Therapeutics for Breast Lymphoma

Drugs for Breast Lymphoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
rituximab Approved 174722-31-7 10201696
2 Antineoplastic Agents, Immunological
3 Immunologic Factors
4 Antirheumatic Agents

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 This Trial is a Prospective Observational Study of Newly Diagnosed Diffuse Large B Cell Primary Breast Lymphomas Terminated NCT01279772
2 Observational Study of Diffuse Large B Cell Primary Breast Lymphomas Treated With RCHOP +/- XRT Terminated NCT01144754 Rituximab

Search NIH Clinical Center for Breast Lymphoma

Genetic Tests for Breast Lymphoma

Anatomical Context for Breast Lymphoma

MalaCards organs/tissues related to Breast Lymphoma:

42
Breast, B Cells, Bone, Lymph Node, Bone Marrow, Skin, Ovary

Publications for Breast Lymphoma

Articles related to Breast Lymphoma:

(show top 50) (show all 148)
# Title Authors Year
1
Management and outcomes of women diagnosed with primary breast lymphoma: a multi-institution experience. ( 29356916 )
2018
2
Breast lymphoma occurring after an invasive ductal breast carcinoma developed in the same area: A case report and literature review. ( 29657120 )
2018
3
Primary breast lymphoma: A mimic of inflammatory breast cancer. ( 30567057 )
2018
4
Coincident primary breast lymphoma and gastrointestinal stromal tumor: case series and molecular mechanisms. ( 30573980 )
2018
5
Primary Breast Lymphoma-Population-Level Insights into an Infrequent but Increasingly Recognized Subtype of Lymphoma. ( 28376146 )
2017
6
Diffuse Large B-Cell Breast Lymphoma: A Case Series. ( 28839450 )
2017
7
Breast lymphoma in a patient with B-cell Non Hodgkin Lymphoma: A case report study. ( 28915427 )
2017
8
Primary Breast Lymphoma in the United States: 1975-2013. ( 28376147 )
2017
9
Primary Breast Lymphoma: A Case Report and Review of the Literature. ( 28839526 )
2017
10
Primary Breast Lymphoma with cutaneous involvement in a patient with Rheumatoid Arthritis - a complication of infliximab therapy? ( 28375194 )
2017
11
Role of core needle biopsy in primary breast lymphoma. ( 28510806 )
2017
12
Primary breast lymphoma: A single center study. ( 28356993 )
2017
13
Primary breast lymphoma: a case report. ( 28270358 )
2017
14
Breast Lymphoma Treatment Outcomes in a Pakistani Population: 20 Years of Experience at a Single Center. ( 27510022 )
2016
15
Primary Breast Lymphoma in a Woman: A Case Report and Review of the Literature. ( 26893404 )
2016
16
Primary Breast Lymphoma: Analysis of 55 Cases of the Spanish Lymphoma Oncology Group. ( 27847267 )
2016
17
Radiation therapy for primary breast lymphoma in male gynecomastia: a rare case report and review of the literature. ( 27225235 )
2016
18
Sonoelastography of Breast Lymphoma. ( 26808169 )
2016
19
Clinicopathological features of thirty patients with primary breast lymphoma and review of the literature. ( 25572809 )
2015
20
First pathological study of canine primary breast lymphoma and the description of its clinicopathological characteristics as an animal model for human primary breast lymphoma. ( 25469251 )
2015
21
Primary breast lymphoma presenting as non-healing axillary abscess. ( 26446318 )
2015
22
F-18 FDG PET/MRI findings of primary breast lymphoma in two cases: FDG PET/MRI findings of primary breast lymphoma. ( 25748090 )
2015
23
MRI features of breast lymphoma: preliminary experience in seven cases. ( 26380896 )
2015
24
Report of a case of primary breast lymphoma highlighting the importance of fine needle aspiration cytology as an initial diagnostic tool. ( 26229252 )
2015
25
Primary breast lymphoma with progression to the scalp. ( 26458702 )
2015
26
Primary breast lymphoma. ( 24953564 )
2014
27
Primary breast lymphoma: 30 years of experience with diagnosis and treatment at a single medical center. ( 24257833 )
2014
28
Breast lymphoma combined with postoperative acute hematopoietic disorder in an immediate breast reconstruction patient. ( 24491455 )
2014
29
Isolated cerebellar hypermetabolism on FDG PET in a case of remitted primary breast lymphoma. ( 24591788 )
2014
30
Primary breast lymphoma: A single-institute experience in Taiwan. ( 25179707 )
2014
31
Synchronous breast cancer and breast lymphoma: two case reports and literature review. ( 25035665 )
2014
32
The features of breast lymphoma on MRI. ( 24029630 )
2013
33
Unusual breast neoplasm: primary breast lymphoma. ( 23749857 )
2013
34
MR imaging of malignant primary breast lymphoma: including diffusion-weighted imaging, histologic features, and a literature review. ( 23846235 )
2013
35
Cytodiagnosis of the primary breast lymphoma in a young woman. ( 24648678 )
2013
36
Primary breast lymphoma. ( 23906238 )
2013
37
Bilateral primary breast lymphoma in a teenage girl with multi-organ involvement. ( 24026996 )
2013
38
Primary breast lymphoma: a single institution's experience. ( 23646311 )
2013
39
Primary breast lymphoma in males-a report of two cases with a review of the literature. ( 24723970 )
2013
40
Primary diffuse large B-cell lymphoma of the nipple: a rare case of breast lymphoma localized in the nipple. ( 23316783 )
2013
41
Breast lymphoma presenting as gynecomastia in male patient. ( 23815269 )
2013
42
Three Cases of Combined Therapy in Primary Breast Lymphoma (PBL) with Successful Outcomes. ( 23885182 )
2013
43
Primary and secondary breast lymphoma: prevalence, clinical signs and radiological features. ( 22665932 )
2012
44
Synchronous bilateral primary breast lymphoma. ( 22616682 )
2012
45
Primary breast lymphoma sequentially relapsed in the peripheral and central nervous system. ( 22426680 )
2012
46
Treatment and outcomes of primary breast lymphoma. ( 23018097 )
2012
47
Fusion PET-CT detection of neurolymphomatosis originating from primary breast lymphoma: A case report and literature review. ( 23162634 )
2012
48
Infiltrating ductal carcinoma of the breast associated with primary breast lymphoma. ( 21475637 )
2011
49
Breast lymphoma complicating anti-tumor necrosis factor therapy in rheumatoid arthritis. ( 21729669 )
2011
50
Analysis of 31 cases of primary breast lymphoma: the effect of nodal involvement and microvascular density. ( 21454188 )
2011

Variations for Breast Lymphoma

Expression for Breast Lymphoma

Search GEO for disease gene expression data for Breast Lymphoma.

Pathways for Breast Lymphoma

Pathways related to Breast Lymphoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.02 CD5 CD79A
2 10.35 BCL6 CD5

GO Terms for Breast Lymphoma

Biological processes related to Breast Lymphoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 immune system process GO:0002376 9.13 BCL6 CD79A PIBF1
2 B cell differentiation GO:0030183 8.62 BCL6 CD79A

Molecular functions related to Breast Lymphoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transmembrane signaling receptor activity GO:0004888 8.62 CD5 CD79A

Sources for Breast Lymphoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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