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MCID: BRS007
MIFTS: 39
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Breast Malignant Phyllodes Tumor
Categories:
Cancer diseases, Rare diseases, Reproductive diseases
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MalaCards integrated aliases for Breast Malignant Phyllodes Tumor:
Characteristics:Orphanet epidemiological data:60
phyllodes tumor of the breast
Age of onset: Adult; Classifications:
ICD10:
35
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NIH Rare Diseases
:
54
Phyllodes tumors of the breast are rare tumors that start in the connective (stromal) tissue of the breast. They get their name from the leaf-like pattern in which they grow (phyllodes means leaf-like in Greek). They are most common in women in their 30s and 40s, although women of any age can be affected. These tumors, which are usually painless, tend to grow quickly, but rarely spread outside of the breast. Most phyllodes tumors are benign. About 1 in 10 are cancerous. The underlying cause of these tumors in unknown. Surgery is the main treatment. Because the tumors can reoccur if they are not removed with enough surrounding tissue, the tumor and at least 1 cm of tissue should be removed. Cancerous phyllodes tumors are often treated with mastectomy. Close follow-up with frequent breast examinations are recommended after surgery.
MalaCards based summary : Breast Malignant Phyllodes Tumor, also known as cystosarcoma phyllodes of the breast, is related to benign prostate phyllodes tumor and prostate malignant phyllodes tumor. An important gene associated with Breast Malignant Phyllodes Tumor is PTS (6-Pyruvoyltetrahydropterin Synthase), and among its related pathways/superpathways is TP53 Regulates Metabolic Genes. The drugs Lidocaine and Anesthetics have been mentioned in the context of this disorder. Affiliated tissues include breast, prostate and kidney, and related phenotypes are cardiovascular system and homeostasis/metabolism Disease Ontology : 12 A breast cancer that is characterized by a prominent infiltrative border, unequivocal sarcomatous areas, and stromal overgrowth and arises_from the stroma, lined by an epithelial and myoepithelial bilayer, forming a leaflike structure. They tend to grow rapidly and present in middle-aged women (40s-50s). |
MGI Mouse Phenotypes related to Breast Malignant Phyllodes Tumor:47
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Drugs for Breast Malignant Phyllodes Tumor (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):(show all 10)
Interventional clinical trials:
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MalaCards organs/tissues related to Breast Malignant Phyllodes Tumor:42
Breast,
Prostate,
Kidney,
Bone,
Ovary
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Articles related to Breast Malignant Phyllodes Tumor:(show all 40)
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Genes related to Breast Malignant Phyllodes Tumor (0 elite genes): - Elite gene
- Cancer Census gene in COSMIC
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Search
GEO
for disease gene expression data for Breast Malignant Phyllodes Tumor.
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Cellular components related to Breast Malignant Phyllodes Tumor according to GeneCards Suite gene sharing:
Molecular functions related to Breast Malignant Phyllodes Tumor according to GeneCards Suite gene sharing:
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