Aliases & Classifications for Breast Mucinous Carcinoma

MalaCards integrated aliases for Breast Mucinous Carcinoma:

Name: Breast Mucinous Carcinoma 12 15
Mucinous Carcinoma of Breast 12 72
Invasive Mucinous Breast Carcinoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3610
NCIt 50 C9131
UMLS 72 C1334807

Summaries for Breast Mucinous Carcinoma

Disease Ontology : 12 A breast adenocarcinoma in which at least one half of the tumor volume is extracellular mucin throughout.

MalaCards based summary : Breast Mucinous Carcinoma, also known as mucinous carcinoma of breast, is related to breast mucinous cystadenocarcinoma and breast columnar cell mucinous carcinoma, and has symptoms including pain An important gene associated with Breast Mucinous Carcinoma is CALR (Calreticulin), and among its related pathways/superpathways is Homologous DNA Pairing and Strand Exchange. Affiliated tissues include breast, lung and skin, and related phenotypes are Reduced mammosphere formation and embryo

Related Diseases for Breast Mucinous Carcinoma

Diseases related to Breast Mucinous Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 12)
# Related Disease Score Top Affiliating Genes
1 breast mucinous cystadenocarcinoma 11.4
2 breast columnar cell mucinous carcinoma 11.4
3 urachal adenocarcinoma 10.1
4 bladder cancer 9.9
5 breast cancer 9.9
6 wilms tumor 5 9.9
7 breast fibroadenoma 9.9
8 adenocarcinoma 9.9
9 mucinous adenocarcinoma 9.9
10 appendix adenocarcinoma 9.9
11 urachal cancer 9.9
12 hereditary breast ovarian cancer syndrome 9.5 RAD51D RAD51C

Graphical network of the top 20 diseases related to Breast Mucinous Carcinoma:



Diseases related to Breast Mucinous Carcinoma

Symptoms & Phenotypes for Breast Mucinous Carcinoma

UMLS symptoms related to Breast Mucinous Carcinoma:


pain

GenomeRNAi Phenotypes related to Breast Mucinous Carcinoma according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Reduced mammosphere formation GR00396-S 8.92 CALR POLD1 RAD51C SLC16A3

MGI Mouse Phenotypes related to Breast Mucinous Carcinoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 embryo MP:0005380 8.92 CALR POLD1 RAD51C RAD51D

Drugs & Therapeutics for Breast Mucinous Carcinoma

Search Clinical Trials , NIH Clinical Center for Breast Mucinous Carcinoma

Genetic Tests for Breast Mucinous Carcinoma

Anatomical Context for Breast Mucinous Carcinoma

MalaCards organs/tissues related to Breast Mucinous Carcinoma:

41
Breast, Lung, Skin

Publications for Breast Mucinous Carcinoma

Articles related to Breast Mucinous Carcinoma:

(show all 26)
# Title Authors PMID Year
1
Severe Bilateral Breast Mucinous Carcinoma with Bilateral Lungs and Cutaneous Metastasis: A Case Report and Literature Review. 38
29707398 2018
2
Erratum: Urachal adenocarcinoma that metastasized to breast was misinterpreted as primary breast mucinous carcinoma: A rare case report and literature review: Erratum. 38
31305695 2017
3
Erratum: The malignant transformation of retrorectal cystic hamartomas with blood irregular antibodies positive: A case report: Erratum Urachal adenocarcinoma that metastasized to breast was misinterpreted as primary breast mucinous carcinoma: A rare case report and literature review: Erratum. 38
31265672 2016
4
Urachal adenocarcinoma that metastasized to breast was misinterpreted as primary breast mucinous carcinoma: A rare case report and literature review. 38
27583877 2016
5
Occurrence of Breast Mucinous Carcinoma After Autologous Fat Grating for Breast Augmentation. 38
26721250 2016
6
[Neuroendocrine differentiation and Wilms' tumor protein-1 expression in breast mucinous carcinoma and their significance]. 38
27045240 2016
7
A rare case of carcinosarcoma of breast: Coexistence of mucinous carcinoma and malignant fibrous histiocytoma. 38
26881584 2015
8
Invasive micropapillary mucinous carcinoma of the breast is associated with poor prognosis. 38
25953688 2015
9
[Expression of human epidermal growth factor receptor 2 in mucinous carcinoma of breast]. 38
25975914 2015
10
Acoustic radiation force impulse elastography for differentiation of malignant and benign breast lesions: a meta-analysis. 38
26131049 2015
11
Mucinous carcinoma of breast with psammomatous calcification: report of a rare case with extensive axillary metastases. 38
24705517 2014
12
The Expression of Glut-1, CAIX, and MCT4 in Mucinous Carcinoma. 38
23843845 2013
13
[Clinicopathologic features of micropapillary variant of pure mucinous carcinoma of breast]. 38
23157830 2012
14
Mucinous carcinoma in a male breast. 38
21713154 2011
15
Biochemical and ultrastructural correlations of calreticulin and thioredoxin expression in breast mucinous carcinoma and infiltrating ductal carcinoma non-special type. 38
20929309 2011
16
Mucinous carcinoma of breast: Cytodiagnosis of a case. 38
21552409 2011
17
Clinicopathological evaluation of 100 cases of mucinous carcinoma of breast with emphasis on axillary staging and special reference to a micropapillary pattern. 38
20962055 2010
18
Clinicopathologic characteristics of mucinous carcinoma of the breast. 38
20718318 2010
19
Mucinous breast carcinoma with myoepithelial-like spindle cells. 38
19263486 2009
20
[Pure colloid carcinoma of the breast: anatomoclinical study of seven cases]. 38
18703371 2009
21
Expression of androgen, estrogen and progesterone receptors in mucinous carcinoma of the breast. 38
18508419 2008
22
Mucinous carcinoma of breast with abundant psammoma bodies in fine-needle aspiration cytology: a case report. 38
17351946 2007
23
Role of fine needle aspiration and tru cut biopsy in diagnosis of mucinous carcinoma of breast--from a radiologist's perspective. 38
16377477 2006
24
Oestrogen and progesterone receptors in primary mucinous carcinoma of skin. 38
16197424 2005
25
FNAC diagnosis of mucinous carcinoma of male breast--a case report. 38
12024934 2001
26
Cytology of mucinous carcinoma of breast: a report of 28 cases with histological correlation. 38
16329537 2000

Variations for Breast Mucinous Carcinoma

Cosmic variations for Breast Mucinous Carcinoma:

9
# Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Mutation CDS Mutation AA GRCh38 Location Conf
1 COSM12459 PIK3CA breast,NS,carcinoma,mucinous c.1637A>G p.Q546R 3:179218307-179218307 15
2 COSM6909041 PAK5 breast,NS,carcinoma,mucinous c.660G>T p.Q220H 20:9580475-9580475 15
3 COSM6865922 NCOR1 breast,NS,carcinoma,mucinous c.242+1G>T p.? 17:16186553-16186553 15
4 COSM6904316 KIT breast,NS,carcinoma,mucinous c.1549C>T p.H517Y 4:54727226-54727226 15
5 COSM436500 ERBB2 breast,NS,carcinoma,mucinous c.2329G>C p.V777L 17:39724747-39724747 15
6 COSM953790 AKT1 breast,NS,carcinoma,mucinous c.238T>C p.W80R 14:104776708-104776708 15

Expression for Breast Mucinous Carcinoma

Search GEO for disease gene expression data for Breast Mucinous Carcinoma.

Pathways for Breast Mucinous Carcinoma

Pathways related to Breast Mucinous Carcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.1 RAD51D RAD51C POLD1

GO Terms for Breast Mucinous Carcinoma

Cellular components related to Breast Mucinous Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nuclear chromosome, telomeric region GO:0000784 9.16 RAD51D POLD1
2 replication fork GO:0005657 8.96 RAD51D RAD51C
3 Rad51B-Rad51C-Rad51D-XRCC2 complex GO:0033063 8.62 RAD51D RAD51C

Biological processes related to Breast Mucinous Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cellular response to DNA damage stimulus GO:0006974 9.43 RAD51D RAD51C POLD1
2 DNA recombination GO:0006310 9.37 RAD51D RAD51C
3 DNA repair GO:0006281 9.33 RAD51D RAD51C POLD1
4 double-strand break repair via homologous recombination GO:0000724 9.32 RAD51D RAD51C
5 telomere maintenance GO:0000723 8.96 RAD51D POLD1
6 reciprocal meiotic recombination GO:0007131 8.62 RAD51D RAD51C

Molecular functions related to Breast Mucinous Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 DNA binding GO:0003677 9.46 RAD51D RAD51C POLD1 CALR
2 DNA-dependent ATPase activity GO:0008094 8.96 RAD51D RAD51C
3 four-way junction DNA binding GO:0000400 8.62 RAD51D RAD51C

Sources for Breast Mucinous Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
Content
Loading form....