Breast Myoepithelial Neoplasm disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Breast Myoepithelial Neoplasm

MalaCards integrated aliases for Breast Myoepithelial Neoplasm:

Name: Breast Myoepithelial Neoplasm ¹² ¹⁵

Malignant Breast Myoepithelioma ⁷¹

Breast Myoepithelial Tumor ⁷¹

Classifications:

MalaCards categories:
Global: Cancer diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:3004

NCIt ⁴⁹ C40389

UMLS ⁷¹ C1511319 C1518167

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Summaries for Breast Myoepithelial Neoplasm

Disease Ontology : ¹² A breast cancer that arises from myoepithelial cells, which are a normal constituent of the salivary acini and ducts and are found between the epithelial cells and the basement membrane.

MalaCards based summary : Breast Myoepithelial Neoplasm, also known as malignant breast myoepithelioma, is related to breast adenomyoepithelioma and breast myoepitheliosis, and has symptoms including pain An important gene associated with Breast Myoepithelial Neoplasm is HSD11B2 (Hydroxysteroid 11-Beta Dehydrogenase 2), and among its related pathways/superpathways is Aldosterone-regulated sodium reabsorption. Affiliated tissues include breast.

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Related Diseases for Breast Myoepithelial Neoplasm

Diseases related to Breast Myoepithelial Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 59)

#	Related Disease	Score	Top Affiliating Genes
1	breast adenomyoepithelioma	28.5	SERPINB5 PLAG1 PIK3R1 P2RY13 MEG3 KRT5
2	breast myoepitheliosis	11.4
3	benign breast adenomyoepithelioma	10.2	KRT5 KRT14
4	ceruminous adenocarcinoma	10.2	KRT5 KRT14
5	squamous cell bile duct carcinoma	10.2	KRT5 KRT14
6	breast metaplastic carcinoma	10.2	KRT5 KRT14
7	epidermolysis bullosa simplex, autosomal recessive 1	10.2	KRT5 KRT14
8	epidermolysis bullosa simplex	10.2	KRT5 KRT14
9	odontoma	10.2	KRT5 KRT14
10	micronodular basal cell carcinoma	10.2	KRT5 KRT14
11	lipid-rich carcinoma	10.2	KRT5 KRT14
12	large cell acanthoma	10.2	KRT5 KRT14
13	eccrine acrospiroma	10.2	KRT5 KRT14
14	eccrine sweat gland neoplasm	10.2	KRT5 KRT14
15	eccrine papillary adenocarcinoma	10.2	KRT5 KRT14
16	epidermolysis bullosa simplex, localized	10.2	KRT5 KRT14
17	apocrine sweat gland neoplasm	10.2	KRT5 KRT14
18	clear cell basal cell carcinoma	10.2	KRT5 KRT14
19	myoepithelial carcinoma	10.2	PLAG1 KRT14
20	intraductal breast benign neoplasm	10.2	KRT5 KRT14
21	breast benign neoplasm	10.2	KRT5 KRT14
22	esophageal adenosquamous carcinoma	10.2	KRT5 KRT14
23	benign peritoneal mesothelioma	10.2	KRT5 KRT14
24	cystic basal cell carcinoma	10.2	KRT5 KRT14
25	reticulate acropigmentation of kitamura	10.2	KRT5 KRT14
26	intraductal papilloma	10.2	KRT5 KRT14
27	epidermolysis bullosa simplex, generalized	10.1	KRT5 KRT14
28	borst-jadassohn intraepidermal carcinoma	10.1	KRT5 KRT14
29	mixed cell type cancer	10.1	PLAG1 KRT5
30	epidermolysis bullosa simplex with mottled pigmentation	10.1	KRT5 KRT14
31	vesiculobullous skin disease	10.1	KRT5 KRT14
32	sebaceous adenocarcinoma	10.1	KRT5 KRT14
33	epidermolysis bullosa simplex, dowling-meara type	10.1	KRT5 KRT14
34	thoracic benign neoplasm	10.1	KRT5 KRT14
35	luminal breast carcinoma a	10.1	KRT5 KRT14
36	epithelial-myoepithelial carcinoma	10.1	PLAG1 KRT14
37	dowling-degos disease	10.1	KRT5 KRT14
38	pachyonychia congenita 1	10.1	KRT5 KRT14
39	salivary gland disease	10.1	PLAG1 KRT5
40	palmoplantar keratoderma, epidermolytic	10.1	KRT5 KRT14
41	spindle cell carcinoma	10.1	KRT5 KRT14
42	primary cutaneous amyloidosis	10.0	KRT5 KRT14
43	skin benign neoplasm	10.0	KRT5 KRT14
44	syringoma	10.0	SERPINB5 PLAG1
45	pre-malignant neoplasm	10.0	KRT5 KRT14
46	skin squamous cell carcinoma	9.9	KRT5 KRT14
47	sweat gland benign neoplasm	9.9	PLAG1 KRT5 KRT14
48	sweat gland disease	9.9	PLAG1 KRT5 KRT14
49	tonsil cancer	9.9	PLAG1 KRT5 KRT14
50	oropharynx cancer	9.9	PLAG1 KRT5 KRT14

Graphical network of the top 20 diseases related to Breast Myoepithelial Neoplasm:

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Symptoms & Phenotypes for Breast Myoepithelial Neoplasm

UMLS symptoms related to Breast Myoepithelial Neoplasm:

pain

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Drugs & Therapeutics for Breast Myoepithelial Neoplasm

Search Clinical Trials , NIH Clinical Center for Breast Myoepithelial Neoplasm

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Genetic Tests for Breast Myoepithelial Neoplasm

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Anatomical Context for Breast Myoepithelial Neoplasm

MalaCards organs/tissues related to Breast Myoepithelial Neoplasm:

⁴⁰

Breast

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Publications for Breast Myoepithelial Neoplasm

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Genes for Breast Myoepithelial Neoplasm

Genes related to Breast Myoepithelial Neoplasm (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	HSD11B2	Hydroxysteroid 11-Beta Dehydrogenase 2	Protein Coding	7.58	DISEASES inferred ¹⁵
2	KRT5	Keratin 5	Protein Coding	6.31	DISEASES inferred ¹⁵
3	ADM5	Adrenomedullin 5 (Putative)	Protein Coding	5.8	DISEASES inferred ¹⁵
4	PLAG1	PLAG1 Zinc Finger	Protein Coding	5.75	DISEASES inferred ¹⁵
5	KRT14	Keratin 14	Protein Coding	5.74	DISEASES inferred ¹⁵
6	PIK3R1	Phosphoinositide-3-Kinase Regulatory Subunit 1	Protein Coding	5.35	DISEASES inferred ¹⁵
7	SERPINB5	Serpin Family B Member 5	Protein Coding	5.25	DISEASES inferred ¹⁵
8	P2RY13	Purinergic Receptor P2Y13	Protein Coding	5.18	DISEASES inferred ¹⁵
9	MEG3	Maternally Expressed 3	RNA Gene	5.09	DISEASES inferred ¹⁵

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Variations for Breast Myoepithelial Neoplasm

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Expression for Breast Myoepithelial Neoplasm

Search GEO for disease gene expression data for Breast Myoepithelial Neoplasm.

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Pathways for Breast Myoepithelial Neoplasm

Pathways related to Breast Myoepithelial Neoplasm according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Aldosterone-regulated sodium reabsorption ³⁶	10.19	PIK3R1 HSD11B2

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GO Terms for Breast Myoepithelial Neoplasm

Biological processes related to Breast Myoepithelial Neoplasm according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	hemidesmosome assembly	GO:0031581	8.62	KRT5 KRT14

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Sources for Breast Myoepithelial Neoplasm

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⁷⁴ Wikipedia