MCID: BRS058
MIFTS: 22

Breast Myoepithelial Neoplasm

Categories: Cancer diseases

Aliases & Classifications for Breast Myoepithelial Neoplasm

MalaCards integrated aliases for Breast Myoepithelial Neoplasm:

Name: Breast Myoepithelial Neoplasm 12 15
Malignant Breast Myoepithelioma 71
Breast Myoepithelial Tumor 71

Classifications:



External Ids:

Disease Ontology 12 DOID:3004
NCIt 49 C40389
UMLS 71 C1511319 C1518167

Summaries for Breast Myoepithelial Neoplasm

Disease Ontology : 12 A breast cancer that arises from myoepithelial cells, which are a normal constituent of the salivary acini and ducts and are found between the epithelial cells and the basement membrane.

MalaCards based summary : Breast Myoepithelial Neoplasm, also known as malignant breast myoepithelioma, is related to breast adenomyoepithelioma and breast myoepitheliosis, and has symptoms including pain An important gene associated with Breast Myoepithelial Neoplasm is HSD11B2 (Hydroxysteroid 11-Beta Dehydrogenase 2), and among its related pathways/superpathways are Keratinization and Cytoskeleton remodeling Neurofilaments. Affiliated tissues include breast, thymus and skin.

Related Diseases for Breast Myoepithelial Neoplasm

Diseases related to Breast Myoepithelial Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 130)
# Related Disease Score Top Affiliating Genes
1 breast adenomyoepithelioma 28.5 SERPINB5 S100P S100A3 MEG3 KRT7 KRT5
2 breast myoepitheliosis 11.4
3 pregnancy adenoma 10.3 KRT5 KRT14
4 esophageal basaloid squamous cell carcinoma 10.3 KRT5 KRT14
5 epidermolysis bullosa simplex, autosomal recessive 1 10.3 KRT5 KRT14
6 odontoma 10.3 KRT5 KRT14
7 lipid-rich carcinoma 10.3 KRT5 KRT14
8 epidermolysis bullosa simplex with mottled pigmentation 10.3 KRT5 KRT14
9 micronodular basal cell carcinoma 10.3 KRT5 KRT14
10 epidermolysis bullosa simplex, generalized 10.3 KRT5 KRT14
11 myoepithelioma 10.3 SERPINB5 KRT14
12 intraductal breast neoplasm 10.3 KRT5 KRT14
13 epidermolysis bullosa simplex, localized 10.3 KRT5 KRT14
14 intracystic papillary adenoma 10.3 KRT5 KRT14
15 reticulate acropigmentation of kitamura 10.2 KRT5 KRT14
16 intraductal papilloma 10.2 KRT5 KRT14
17 hard palate cancer 10.2 KRT5 KRT14
18 vesiculobullous skin disease 10.2 KRT5 KRT14
19 sebaceous adenocarcinoma 10.2 KRT5 KRT14
20 epidermolysis bullosa simplex, dowling-meara type 10.2 KRT5 KRT14
21 pachyonychia congenita 1 10.1 KRT5 KRT14
22 palmoplantar keratoderma, epidermolytic 10.1 KRT5 KRT14
23 luminal breast carcinoma 10.1 KRT5 KRT14
24 dowling-degos disease 10.1 KRT5 KRT14
25 breast myoepithelial carcinoma 10.0 SERPINB5 KRT5 KRT14
26 inverted transitional papilloma 10.0 KRT7 KRT5
27 malignant spiradenoma 10.0 KRT7 KRT5
28 ceruminoma 10.0 KRT7 KRT5
29 ureter adenocarcinoma 10.0 KRT7 KRT5
30 subareolar duct papillomatosis 10.0 KRT7 KRT5
31 bone leiomyosarcoma 10.0 KRT7 KRT5
32 nipple neoplasm 10.0 KRT7 KRT5
33 microinvasive cervical squamous cell carcinoma 10.0 KRT7 KRT5
34 skin benign neoplasm 10.0 KRT5 KRT14
35 myoepithelial carcinoma 10.0 KRT7 KRT14
36 external ear carcinoma 10.0 KRT7 KRT5
37 vulvar apocrine adenocarcinoma 10.0 KRT7 KRT5
38 gastric squamous cell carcinoma 10.0 KRT7 KRT5
39 middle ear adenoma 10.0 KRT7 KRT5
40 eccrine papillary adenocarcinoma 10.0 KRT7 KRT5
41 necrotizing sialometaplasia 10.0 KRT7 KRT5
42 sensory organ benign neoplasm 10.0 KRT7 KRT5
43 bile duct mucoepidermoid carcinoma 10.0 KRT7 KRT5
44 breast mucinous carcinoma 10.0 KRT7 KRT5
45 spiradenoma 10.0 KRT7 KRT14
46 clear cell hidradenoma 10.0 KRT7 KRT5
47 hidradenoma 10.0 KRT7 KRT5
48 eccrine sweat gland cancer 10.0 KRT7 KRT5
49 sweat gland cancer 10.0 KRT7 KRT5
50 middle ear adenocarcinoma 10.0 KRT7 KRT5

Graphical network of the top 20 diseases related to Breast Myoepithelial Neoplasm:



Diseases related to Breast Myoepithelial Neoplasm

Symptoms & Phenotypes for Breast Myoepithelial Neoplasm

UMLS symptoms related to Breast Myoepithelial Neoplasm:


pain

Drugs & Therapeutics for Breast Myoepithelial Neoplasm

Search Clinical Trials , NIH Clinical Center for Breast Myoepithelial Neoplasm

Genetic Tests for Breast Myoepithelial Neoplasm

Anatomical Context for Breast Myoepithelial Neoplasm

MalaCards organs/tissues related to Breast Myoepithelial Neoplasm:

40
Breast, Thymus, Skin, Bone, Heart, Lung, Salivary Gland

Publications for Breast Myoepithelial Neoplasm

Variations for Breast Myoepithelial Neoplasm

Expression for Breast Myoepithelial Neoplasm

Search GEO for disease gene expression data for Breast Myoepithelial Neoplasm.

Pathways for Breast Myoepithelial Neoplasm

Pathways related to Breast Myoepithelial Neoplasm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.59 KRT7 KRT5 KRT14
2
Show member pathways
10.83 KRT7 KRT5 KRT14

GO Terms for Breast Myoepithelial Neoplasm

Cellular components related to Breast Myoepithelial Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 intermediate filament GO:0005882 9.13 KRT7 KRT5 KRT14
2 keratin filament GO:0045095 8.8 KRT7 KRT5 KRT14

Biological processes related to Breast Myoepithelial Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 keratinization GO:0031424 9.33 KRT7 KRT5 KRT14
2 hemidesmosome assembly GO:0031581 8.96 KRT5 KRT14
3 cornification GO:0070268 8.8 KRT7 KRT5 KRT14

Molecular functions related to Breast Myoepithelial Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transition metal ion binding GO:0046914 8.62 S100P S100A3

Sources for Breast Myoepithelial Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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