MCID: BRS005
MIFTS: 25

Breast Neuroendocrine Neoplasm

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Breast Neuroendocrine Neoplasm

MalaCards integrated aliases for Breast Neuroendocrine Neoplasm:

Name: Breast Neuroendocrine Neoplasm 12 15 74
Neuroendocrine Tumor of the Breast 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3009
NCIt 51 C5169
UMLS 74 C1332635

Summaries for Breast Neuroendocrine Neoplasm

Disease Ontology : 12 A breast benign neoplasm that forms from cells that release hormones into the blood in response to a signal from the nervous system.

MalaCards based summary : Breast Neuroendocrine Neoplasm, also known as neuroendocrine tumor of the breast, is related to neuroendocrine tumor and ectopic cushing syndrome. An important gene associated with Breast Neuroendocrine Neoplasm is SYP (Synaptophysin), and among its related pathways/superpathways are Peptide ligand-binding receptors and cAMP signaling pathway. Affiliated tissues include breast.

Related Diseases for Breast Neuroendocrine Neoplasm

Diseases related to Breast Neuroendocrine Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 32)
# Related Disease Score Top Affiliating Genes
1 neuroendocrine tumor 30.4 SSTR2 SYP
2 ectopic cushing syndrome 10.2 SSTR1 SYP
3 carcinoid tumors, intestinal 10.1 SSTR2 SYP
4 primary pigmented nodular adrenocortical disease 10.1 SSTR1 SYP
5 ovarian carcinosarcoma 10.1 ERBB2 SYP
6 olfactory neuroblastoma 10.1 SSTR2 SYP
7 hormone producing pituitary cancer 10.1 SSTR2 SSTR5
8 mixed ductal-endocrine carcinoma 10.1 SSTR2 SYP
9 cell type benign neoplasm 10.1 SSTR5 SYP
10 mixed cell type cancer 10.1 ERBB2 SYP
11 granulosa cell tumor of the ovary 10.1 ERBB2 SYP
12 tubular adenocarcinoma 10.0 ERBB2 SYP
13 peritoneal serous adenocarcinoma 10.0 PIP SYP
14 sweat gland cancer 10.0 ERBB2 SYP
15 oncogenic osteomalacia 10.0 SSTR1 SSTR3 SSTR5
16 pancreatic endocrine carcinoma 9.9 SSTR2 SSTR5 SYP
17 endocrine gland cancer 9.9 ERBB2 SYP
18 acromegaly 9.9 SSTR1 SSTR2 SSTR5
19 thyroid carcinoma, familial medullary 9.9 SSTR1 SSTR2 SSTR5
20 vulval paget's disease 9.8 ERBB2 PIP
21 vulva adenocarcinoma 9.8 ERBB2 PIP
22 microglandular adenosis 9.8 ERBB2 PIP
23 paget disease, extramammary 9.8 ERBB2 PIP
24 breast benign neoplasm 9.8 ERBB2 PIP
25 thoracic benign neoplasm 9.8 ERBB2 PIP
26 lipid-rich carcinoma 9.8 ERBB2 PIP
27 hidradenocarcinoma 9.8 ERBB2 PIP
28 meningioma, familial 9.8 SSTR2 SYP
29 pre-malignant neoplasm 9.7 ERBB2 PIP
30 pituitary adenoma, prolactin-secreting 9.7 SSTR1 SSTR2 SSTR3 SSTR5
31 medulloblastoma 9.7 ERBB2 SSTR2 SYP
32 breast ductal carcinoma 9.7 ERBB2 PIP

Graphical network of the top 20 diseases related to Breast Neuroendocrine Neoplasm:



Diseases related to Breast Neuroendocrine Neoplasm

Symptoms & Phenotypes for Breast Neuroendocrine Neoplasm

Drugs & Therapeutics for Breast Neuroendocrine Neoplasm

Search Clinical Trials , NIH Clinical Center for Breast Neuroendocrine Neoplasm

Genetic Tests for Breast Neuroendocrine Neoplasm

Anatomical Context for Breast Neuroendocrine Neoplasm

MalaCards organs/tissues related to Breast Neuroendocrine Neoplasm:

42
Breast

Publications for Breast Neuroendocrine Neoplasm

Articles related to Breast Neuroendocrine Neoplasm:

# Title Authors Year
1
Well-differentiated neuroendocrine tumor of the breast with extensive lymphatic and vascular infiltration. ( 27862661 )
2016
2
Primary neuroendocrine tumor of the breast. ( 25808825 )
2015
3
Well-differentiated neuroendocrine tumor of the breast with recurrence due to needle tract seeding. ( 25560191 )
2015
4
68Ga DOTANOC PET/CT in primary neuroendocrine tumor of the breast. ( 24566407 )
2014
5
Primary large-cell neuroendocrine tumor of the breast. ( 23458218 )
2013
6
Primary neuroendocrine tumor of the breast: imaging features. ( 23690703 )
2013
7
Small cell neuroendocrine tumor of the breast in a 40 year-old woman: a case report. ( 20591162 )
2010
8
Multinodular cutaneous spread in neuroendocrine tumor of the breast : an unusual presentation. ( 18039021 )
2007
9
Neuroendocrine tumor of the breast. ( 16536254 )
2006
10
Primary neuroendocrine tumor of the breast. ( 9330271 )
1997

Variations for Breast Neuroendocrine Neoplasm

Expression for Breast Neuroendocrine Neoplasm

Search GEO for disease gene expression data for Breast Neuroendocrine Neoplasm.

Pathways for Breast Neuroendocrine Neoplasm

GO Terms for Breast Neuroendocrine Neoplasm

Cellular components related to Breast Neuroendocrine Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 integral component of membrane GO:0016021 9.5 ERBB2 SSTR1 SSTR2 SSTR3 SSTR4 SSTR5
2 integral component of plasma membrane GO:0005887 9.1 ERBB2 SSTR1 SSTR2 SSTR3 SSTR4 SSTR5

Biological processes related to Breast Neuroendocrine Neoplasm according to GeneCards Suite gene sharing:

(show all 12)
# Name GO ID Score Top Affiliating Genes
1 signal transduction GO:0007165 9.95 ERBB2 SSTR1 SSTR2 SSTR3 SSTR4 SSTR5
2 G protein-coupled receptor signaling pathway GO:0007186 9.89 SSTR1 SSTR2 SSTR3 SSTR4 SSTR5
3 negative regulation of cell proliferation GO:0008285 9.77 SSTR1 SSTR2 SSTR3 SSTR4 SSTR5
4 spermatogenesis GO:0007283 9.69 SSTR1 SSTR2 SSTR3
5 neuropeptide signaling pathway GO:0007218 9.65 SSTR1 SSTR2 SSTR3 SSTR4 SSTR5
6 cerebellum development GO:0021549 9.63 SSTR1 SSTR2 SSTR3
7 forebrain development GO:0030900 9.62 SSTR1 SSTR2 SSTR3 SSTR4
8 cellular response to estradiol stimulus GO:0071392 9.61 SSTR1 SSTR2 SSTR3
9 response to starvation GO:0042594 9.58 SSTR1 SSTR2 SSTR3
10 cellular response to glucocorticoid stimulus GO:0071385 9.46 SSTR2 SSTR3 SSTR4 SSTR5
11 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger GO:0007187 9.35 SSTR1 SSTR2 SSTR3 SSTR4 SSTR5
12 somatostatin signaling pathway GO:0038170 9.02 SSTR1 SSTR2 SSTR3 SSTR4 SSTR5

Molecular functions related to Breast Neuroendocrine Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 G protein-coupled receptor activity GO:0004930 9.55 SSTR1 SSTR2 SSTR3 SSTR4 SSTR5
2 neuropeptide binding GO:0042923 9.35 SSTR1 SSTR2 SSTR3 SSTR4 SSTR5
3 somatostatin receptor activity GO:0004994 9.02 SSTR1 SSTR2 SSTR3 SSTR4 SSTR5

Sources for Breast Neuroendocrine Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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