MCID: BRS032
MIFTS: 30

Breast Papillary Carcinoma

Categories: Cancer diseases

Aliases & Classifications for Breast Papillary Carcinoma

MalaCards integrated aliases for Breast Papillary Carcinoma:

Name: Breast Papillary Carcinoma 12 15
Solid Papillary Carcinoma of the Breast 12
Papillary Carcinoma of the Breast 12
Breast Solid Papillary Carcinoma 12
Papillary Carcinoma of Breast 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5592
NCIt 49 C6870
UMLS 71 C1336027

Summaries for Breast Papillary Carcinoma

Disease Ontology : 12 A breast carcinoma that is characterized by the presence of arborescent fibrovascular stalks lined by epithelial cells, grossly forming a circumscribed mass.

MalaCards based summary : Breast Papillary Carcinoma, also known as solid papillary carcinoma of the breast, is related to bilateral breast cancer and mammary paget's disease. An important gene associated with Breast Papillary Carcinoma is SYP (Synaptophysin), and among its related pathways/superpathways is Signaling by ERBB4. Affiliated tissues include breast, lung and thyroid, and related phenotype is Decreased viability in esophageal squamous lineage.

Related Diseases for Breast Papillary Carcinoma

Diseases related to Breast Papillary Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 278)
# Related Disease Score Top Affiliating Genes
1 bilateral breast cancer 29.6 PGR ESR1 ERBB2
2 mammary paget's disease 29.6 PGR ESR1 ERBB2
3 signet ring cell adenocarcinoma 29.6 ERBB2 CHGA
4 papillary carcinoma 29.5 SYP PGR ESR1 ERBB2 CHGA
5 in situ carcinoma 29.2 PGR KRT5 ESR1 ERBB2
6 ductal carcinoma in situ 29.2 PGR KRT5 ESR1 ERBB2
7 apocrine adenocarcinoma 28.7 PGR KRT5 ESR1 ERBB2
8 cribriform carcinoma 28.7 PGR KRT5 ESR1 ERBB2
9 intraductal papilloma 28.7 PGR KRT5 ESR1 ERBB2
10 tubular adenocarcinoma 28.7 SYP PGR ESR1 ERBB2 CHGA
11 sweat gland cancer 28.3 SYP PGR KRT5 ESR1 ERBB2
12 intracystic papillary adenoma 28.1 PGR KRT5 ESR1 ERBB2 CHGA
13 lung meningioma 10.4 SYP PGR
14 glycogen-rich clear cell breast carcinoma 10.4 SYP PGR
15 mucinous adenofibroma 10.3 SYP ESR1
16 prostate stromal sarcoma 10.3 SYP PGR
17 bartholin's gland adenoid cystic carcinoma 10.3 PGR ESR1
18 chronic tympanitis 10.3 PGR ESR1
19 bartholin's gland adenoma 10.3 PGR ESR1
20 granulomatous endometritis 10.3 PGR ESR1
21 endometritis 10.3 PGR ESR1
22 bartholin's gland benign neoplasm 10.3 PGR ESR1
23 vestibular gland benign neoplasm 10.3 PGR ESR1
24 lung leiomyoma 10.3 PGR ESR1
25 vulvar syringoma 10.3 PGR ESR1
26 trigonitis 10.3 PGR ESR1
27 vagina leiomyosarcoma 10.3 PGR ESR1
28 adult type testicular granulosa cell tumor 10.3 PGR ESR1
29 ovarian seromucinous carcinoma 10.3 PGR ESR1
30 breast leiomyoma 10.3 PGR ESR1
31 intravenous leiomyomatosis 10.3 PGR ESR1
32 liver leiomyoma 10.3 PGR ESR1
33 mammographic density 10.3 PGR ESR1
34 vulvar leiomyoma 10.3 PGR ESR1
35 bizarre leiomyoma 10.3 PGR ESR1
36 chordoid glioma 10.3 SYP PGR
37 spinal cancer 10.3 SYP PGR
38 endosalpingiosis 10.3 PGR ESR1
39 progesterone resistance 10.3 PGR ESR1
40 cervical mucinous adenocarcinoma 10.3 PGR ESR1
41 adenomyoma 10.3 PGR ESR1
42 ureter small cell carcinoma 10.3 SYP CHGA
43 gender identity disorder 10.3 PGR ESR1
44 juvenile nasopharyngeal angiofibroma 10.3 PGR ESR1
45 primary hepatic neuroendocrine carcinoma 10.3 SYP CHGA
46 perivascular epithelioid cell tumor 10.3 SYP PGR
47 ovarian large-cell neuroendocrine carcinoma 10.3 SYP CHGA
48 pancreas lymphoma 10.3 SYP CHGA
49 small cell carcinoma of the bladder 10.3 SYP CHGA
50 vulvar benign neoplasm 10.3 PGR ESR1

Graphical network of the top 20 diseases related to Breast Papillary Carcinoma:



Diseases related to Breast Papillary Carcinoma

Symptoms & Phenotypes for Breast Papillary Carcinoma

GenomeRNAi Phenotypes related to Breast Papillary Carcinoma according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability in esophageal squamous lineage GR00235-A 9.1 CHGA ERBB2 ESR1 PGR SLC16A3 SLC16A4

Drugs & Therapeutics for Breast Papillary Carcinoma

Search Clinical Trials , NIH Clinical Center for Breast Papillary Carcinoma

Genetic Tests for Breast Papillary Carcinoma

Anatomical Context for Breast Papillary Carcinoma

MalaCards organs/tissues related to Breast Papillary Carcinoma:

40
Breast, Lung, Thyroid, Ovary, Prostate, Cervix, Thymus

Publications for Breast Papillary Carcinoma

Articles related to Breast Papillary Carcinoma:

(show all 30)
# Title Authors PMID Year
1
Fine-needle aspiration cytology of solid papillary carcinoma of the breast. 61
31513348 2020
2
Solid Papillary Carcinoma of the Breast: Magnetic Resonance Mammography, Digital Mammography, and Ultrasound Findings. 61
29613993 2018
3
Solid papillary carcinoma of the breast with an associated Cytokeratin 7- negative Paget's disease of the nipple. Report of a first case. 61
29265587 2018
4
Endocrine mucin-producing sweat gland carcinoma: A study of 11 cases with molecular analysis. 61
29943394 2018
5
A pilot evaluation of magnetic resonance imaging characteristics seen with solid papillary carcinomas of the breast in 4 patients. 61
28784112 2017
6
Endocrine Mucin-Producing Sweat Gland Carcinoma, a Histological Challenge. 61
28299221 2017
7
Clinicopathologic Characteristics of Solid Papillary Carcinoma of the Breast. 61
27438988 2016
8
Metastatic gastrinoma in the breast mimicking primary solid papillary carcinoma. 61
27342908 2016
9
Solid papillary carcinoma of the breast: A special entity needs to be distinguished from conventional invasive carcinoma avoiding over-treatment. 61
27017244 2016
10
[Endocrine mucin-producing sweat gland carcinoma. three case reports with a brief review of the literature]. 61
25085634 2014
11
Expression of glycolysis-related proteins in solid papillary carcinoma of the breast according to basement membrane status. 61
24719122 2014
12
Invasive (solid) Papillary Carcinoma of the Breast: A Report of Two Cases. 61
23905125 2013
13
Endocrine mucin-producing sweat gland carcinoma: report of two cases of an under-recognized malignant neoplasm and review of the literature. 61
22892473 2013
14
Synchronous bilateral solid papillary carcinomas of the breast. 61
23844308 2013
15
Solid papillary carcinoma of the breast: a pathologically and clinically distinct breast tumor. 61
23020734 2012
16
A case of endocrine mucin-producing sweat gland carcinoma. 61
22524664 2012
17
Solid papillary carcinoma of the breast with neuroendocrine features in a pregnant woman: a case report. 61
21876491 2011
18
Solid papillary carcinoma of the breast: imprint cytological and histological findings. 61
20340006 2010
19
Loss of myoepithelium is variable in solid papillary carcinoma of the breast. 61
17927587 2007
20
Cytological study of 20 cases of solid-papillary carcinoma of the breast. 61
17580353 2007
21
Solid-papillary carcinoma of the breast: clinicopathological study of 20 cases. 61
17587241 2007
22
Clinicopathologic analysis of solid papillary carcinoma of the breast and associated invasive carcinomas. 61
16625097 2006
23
Fine needle aspiration cytology of solid papillary carcinoma of the breast. A report of four cases. 61
12685198 2003
24
Solid papillary carcinoma of the breast: report of two cases. 61
11407528 2001
25
Fine needle aspiration cytology of a solid papillary carcinoma of the breast. A case report with immunohistochemical studies. 61
9622695 1998
26
Endocrine mucin-producing sweat gland carcinoma: a cutaneous neoplasm analogous to solid papillary carcinoma of breast. 61
9414195 1997
27
Solid papillary carcinoma of breast: an ultrastructural study. 61
9090026 1997
28
Solid papillary carcinoma of the breast. 61
9042298 1997
29
Solid papillary carcinoma of the breast. A form of intraductal carcinoma with endocrine differentiation frequently associated with mucinous carcinoma. 61
7573685 1995
30
[Five simultaneous neoplasms]. 61
2825093 1987

Variations for Breast Papillary Carcinoma

Cosmic variations for Breast Papillary Carcinoma:

9 (show all 24)
# Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Mutation CDS Mutation AA GRCh38 Location Conf
1 COSM87897745 TP53 breast,NS,carcinoma,papillary c.524G>A p.R175H 17:7675088-7675088 21
2 COSM87132245 PIK3CA breast,NS,carcinoma,papillary c.3140A>G p.H1047R 3:179234297-179234297 21
3 COSM97107336 NRAS breast,NS,carcinoma,papillary c.183A>C p.Q61H 1:114713907-114713907 21
4 COSM88889220 APC breast,NS,carcinoma,papillary c.3571C>T p.Q1191* 5:112839165-112839165 21
5 COSM112253124 breast,NS,carcinoma,papillary c.524G>A p.R175H 17:7675088-7675088 21
6 COSM105619860 breast,NS,carcinoma,papillary c.524G>A p.R175H 17:7675088-7675088 21
7 COSM122733880 breast,NS,carcinoma,papillary c.128G>A p.R43H 17:7675088-7675088 21
8 COSM148932633 breast,NS,carcinoma,papillary c.*220A>G p.? 3:179234297-179234297 21
9 COSM106052917 breast,NS,carcinoma,papillary c.524G>A p.R175H 17:7675088-7675088 21
10 COSM143156608 breast,NS,carcinoma,papillary c.47G>A p.R16H 17:7675088-7675088 21
11 COSM143943565 breast,NS,carcinoma,papillary c.47G>A p.R16H 17:7675088-7675088 21
12 COSM122404515 breast,NS,carcinoma,papillary c.3571C>T p.Q1191* 5:112839165-112839165 21
13 COSM144650780 breast,NS,carcinoma,papillary c.407G>A p.R136H 17:7675088-7675088 21
14 COSM121875575 breast,NS,carcinoma,papillary c.128G>A p.R43H 17:7675088-7675088 21
15 COSM145017326 breast,NS,carcinoma,papillary c.407G>A p.R136H 17:7675088-7675088 21
16 COSM144013113 breast,NS,carcinoma,papillary c.491G>A p.R164H 17:7675088-7675088 21
17 COSM142837093 breast,NS,carcinoma,papillary c.524G>A p.R175H 17:7675088-7675088 21
18 COSM122271291 breast,NS,carcinoma,papillary c.128G>A p.R43H 17:7675088-7675088 21
19 COSM144086975 breast,NS,carcinoma,papillary c.47G>A p.R16H 17:7675088-7675088 21
20 COSM142559914 breast,NS,carcinoma,papillary c.407G>A p.R136H 17:7675088-7675088 21
21 COSM111758247 breast,NS,carcinoma,papillary c.524G>A p.R175H 17:7675088-7675088 21
22 COSM143370595 breast,NS,carcinoma,papillary c.407G>A p.R136H 17:7675088-7675088 21
23 COSM144309944 breast,NS,carcinoma,papillary c.407G>A p.R136H 17:7675088-7675088 21
24 COSM93183307 breast,NS,carcinoma,papillary c.524G>A p.R175H 17:7675088-7675088 21

Expression for Breast Papillary Carcinoma

Search GEO for disease gene expression data for Breast Papillary Carcinoma.

Pathways for Breast Papillary Carcinoma

Pathways related to Breast Papillary Carcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
10.83 PGR ESR1 ERBB2

GO Terms for Breast Papillary Carcinoma

Cellular components related to Breast Papillary Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 membrane GO:0016020 9.23 SYP SLC16A4 SLC16A3 PGR KRT5 ESR1

Biological processes related to Breast Papillary Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 monocarboxylic acid transport GO:0015718 8.62 SLC16A4 SLC16A3

Molecular functions related to Breast Papillary Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nuclear receptor activity GO:0004879 9.16 PGR ESR1
2 steroid binding GO:0005496 8.96 PGR ESR1
3 monocarboxylic acid transmembrane transporter activity GO:0008028 8.62 SLC16A4 SLC16A3

Sources for Breast Papillary Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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