MCID: BRS060
MIFTS: 31

Breast Papillomatosis

Categories: Cancer diseases

Aliases & Classifications for Breast Papillomatosis

MalaCards integrated aliases for Breast Papillomatosis:

Name: Breast Papillomatosis 12 15 73
Papillomatosis of the Breast 12

Classifications:



External Ids:

Disease Ontology 12 DOID:1634
NCIt 50 C6977
UMLS 73 C1332636

Summaries for Breast Papillomatosis

Disease Ontology : 12 A breast benign neoplasm that is characterized by papillary proliferations within multiple terminal duct-lobular units or in the distal branches (terminal ducts) of the duct system.

MalaCards based summary : Breast Papillomatosis, also known as papillomatosis of the breast, is related to papilloma and squamous cell carcinoma. An important gene associated with Breast Papillomatosis is ERBB2 (Erb-B2 Receptor Tyrosine Kinase 2), and among its related pathways/superpathways are Endometrial cancer and Pathways in cancer. Affiliated tissues include breast, lung and skin, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Wikipedia : 76 Papillomatosis of the breasts is a proliferative epithelial lesion (epitheliosis) of the breast.... more...

Related Diseases for Breast Papillomatosis

Diseases in the Breast Papillomatosis family:

Breast Juvenile Papillomatosis

Diseases related to Breast Papillomatosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 81)
# Related Disease Score Top Affiliating Genes
1 papilloma 30.6 CCND1 CDKN2A
2 squamous cell carcinoma 29.4 CCND1 CDKN2A ERBB2
3 breast juvenile papillomatosis 11.2
4 breast intraductal papillomatosis 11.2
5 non-proliferative fibrocystic change of the breast 10.0 CCND1 ERBB2
6 hidradenocarcinoma 10.0 CCND1 ERBB2
7 estrogen-receptor positive breast cancer 10.0 CCND1 ERBB2
8 ductal carcinoma in situ 10.0 CCND1 ERBB2
9 stomach disease 10.0 CCND1 ERBB2
10 breast ductal carcinoma 10.0 CCND1 ERBB2
11 tonsil squamous cell carcinoma 10.0 CCND1 CDKN2A
12 bowenoid papulosis 10.0 CCND1 CDKN2A
13 skin carcinoma in situ 10.0 CCND1 CDKN2A
14 endometrial squamous cell carcinoma 10.0 CCND1 CDKN2A
15 ischemic fasciitis 10.0 CCND1 CDKN2A
16 verrucous carcinoma 10.0 CCND1 CDKN2A
17 chondromyxoid fibroma 10.0 CCND1 CDKN2A
18 laryngeal disease 9.9 CCND1 CDKN2A
19 oropharynx cancer 9.9 CCND1 CDKN2A
20 pharynx cancer 9.9 CCND1 CDKN2A
21 inverted papilloma 9.9 CCND1 CDKN2A
22 penile cancer 9.9 CCND1 CDKN2A
23 nasopharyngeal disease 9.9 CCND1 CDKN2A
24 retinal cancer 9.9 CCND1 CDKN2A
25 cervix disease 9.9 CCND1 CDKN2A
26 fallopian tube endometrioid adenocarcinoma 9.9 CDKN2A ERBB2
27 ocular cancer 9.9 CCND1 CDKN2A
28 vulval paget's disease 9.9 CDKN2A ERBB2
29 tongue cancer 9.9 CCND1 CDKN2A
30 vulva adenocarcinoma 9.9 CDKN2A ERBB2
31 laryngeal squamous cell carcinoma 9.9 CCND1 CDKN2A
32 bladder urothelial carcinoma 9.9 CCND1 ERBB2
33 ewing's family of tumors 9.9 CDKN2A ERBB2
34 oral cancer 9.9 CCND1 CDKN2A
35 tonsil cancer 9.9 CDKN2A ERBB2
36 barrett's adenocarcinoma 9.9 CDKN2A ERBB2
37 nervous system cancer 9.9 CCND1 CDKN2A
38 in situ carcinoma 9.9 CDKN2A ERBB2
39 larynx cancer 9.9 CCND1 CDKN2A
40 cervical adenocarcinoma 9.9 CDKN2A ERBB2
41 cholangiocarcinoma 9.9 CCND1 ERBB2
42 pseudo-turner syndrome 9.9
43 noonan syndrome 1 9.9
44 mantle cell lymphoma 9.9 CCND1 CDKN2A
45 lynch syndrome 9.9 CCND1 CDKN2A
46 endometrial adenocarcinoma 9.9 CDKN2A ERBB2
47 gastrointestinal stromal tumor 9.9 CCND1 CDKN2A
48 transitional cell carcinoma 9.9 CDKN2A ERBB2
49 gallbladder cancer 9.8 CDKN2A ERBB2
50 b-cell lymphomas 9.8 CCND1 CDKN2A

Graphical network of the top 20 diseases related to Breast Papillomatosis:



Diseases related to Breast Papillomatosis

Symptoms & Phenotypes for Breast Papillomatosis

GenomeRNAi Phenotypes related to Breast Papillomatosis according to GeneCards Suite gene sharing:

26 (show all 16)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-126 9.55 CCND1
2 Increased shRNA abundance (Z-score > 2) GR00366-A-152 9.55 CCND1
3 Increased shRNA abundance (Z-score > 2) GR00366-A-16 9.55 CCND1
4 Increased shRNA abundance (Z-score > 2) GR00366-A-161 9.55 ERBB2
5 Increased shRNA abundance (Z-score > 2) GR00366-A-163 9.55 CCND1 ERBB2
6 Increased shRNA abundance (Z-score > 2) GR00366-A-168 9.55 ERBB2
7 Increased shRNA abundance (Z-score > 2) GR00366-A-177 9.55 CCND1
8 Increased shRNA abundance (Z-score > 2) GR00366-A-199 9.55 CCND1
9 Increased shRNA abundance (Z-score > 2) GR00366-A-207 9.55 ERBB2
10 Increased shRNA abundance (Z-score > 2) GR00366-A-21 9.55 CCND1
11 Increased shRNA abundance (Z-score > 2) GR00366-A-210 9.55 CCND1
12 Increased shRNA abundance (Z-score > 2) GR00366-A-25 9.55 CCND1
13 Increased shRNA abundance (Z-score > 2) GR00366-A-32 9.55 ERBB2
14 Increased shRNA abundance (Z-score > 2) GR00366-A-36 9.55 CCND1
15 Increased shRNA abundance (Z-score > 2) GR00366-A-63 9.55 ERBB2
16 Increased shRNA abundance (Z-score > 2) GR00366-A-85 9.55 ERBB2

MGI Mouse Phenotypes related to Breast Papillomatosis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 9.33 CCND1 CDKN2A ERBB2
2 neoplasm MP:0002006 9.13 CCND1 CDKN2A ERBB2
3 respiratory system MP:0005388 8.8 CCND1 CDKN2A ERBB2

Drugs & Therapeutics for Breast Papillomatosis

Search Clinical Trials , NIH Clinical Center for Breast Papillomatosis

Genetic Tests for Breast Papillomatosis

Anatomical Context for Breast Papillomatosis

MalaCards organs/tissues related to Breast Papillomatosis:

41
Breast, Lung, Skin, Bone, Tonsil, Pancreas, Cervix

Publications for Breast Papillomatosis

Articles related to Breast Papillomatosis:

(show all 20)
# Title Authors Year
1
Juvenile Papillomatosis of the Breast in a Pre-Pubertal Girl: An Uncommon Diagnosis. ( 29322120 )
2018
2
Juvenile papillomatosis of the breast in young male: a case report. ( 22018260 )
2011
3
Juvenile papillomatosis of the breast associated with neurofibromatosis 1. ( 16883593 )
2007
4
Juvenile papillomatosis of the breast in a 9-year-old girl. ( 11315290 )
2001
5
Juvenile papillomatosis of the breast in male infants: two case reports. ( 10663852 )
2000
6
A Case of Multiple Juvenile Papillomatosis of the Breast and Its Immunohistochemical Pathology. ( 11091647 )
1998
7
Giant juvenile papillomatosis of the breast: report of two cases. ( 9185400 )
1997
8
Juvenile papillomatosis of the breast (Swiss cheese disease) ( 9275926 )
1997
9
Case report: MR imaging of juvenile papillomatosis of the breast. ( 8983594 )
1996
10
Intraduct papillomatosis of the breast in a peripubertal male. ( 7971575 )
1994
11
Juvenile papillomatosis of the breast. ( 8103370 )
1993
12
Juvenile papillomatosis of the breast. A multidisciplinary study. ( 2014142 )
1991
13
Juvenile papillomatosis of the breast. A follow-up study of 41 patients having biopsies before 1979. ( 2158224 )
1990
14
The continuing evolution of our understanding of juvenile papillomatosis of the breast. ( 2158228 )
1990
15
Juvenile papillomatosis of the breast: sonographic appearance. ( 3055027 )
1988
16
Three-dimensional atypical structure in intraductal carcinoma differentiating from papilloma and papillomatosis of the breast. ( 2983798 )
1985
17
Extensive squamous metaplasia simulating squamous cell carcinoma in benign breast papillomatosis. ( 6642498 )
1983
18
Juvenile papillomatosis of the breast and family history of breast carcinoma. ( 7074576 )
1982
19
Intraductal papillomatosis of the breast. Report of a case in a ten-year-old girl. ( 5936652 )
1966
20
BREAST PAPILLOMATOSIS. ( 14252363 )
1964

Variations for Breast Papillomatosis

Expression for Breast Papillomatosis

Search GEO for disease gene expression data for Breast Papillomatosis.

Pathways for Breast Papillomatosis

Pathways related to Breast Papillomatosis according to GeneCards Suite gene sharing:

(show all 24)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.33 CCND1 CDKN2A ERBB2
2 12.27 CCND1 CDKN2A ERBB2
3
Show member pathways
12.17 CCND1 CDKN2A ERBB2
4
Show member pathways
12.1 CCND1 CDKN2A ERBB2
5
Show member pathways
11.99 CCND1 CDKN2A
6 11.97 CCND1 CDKN2A
7
Show member pathways
11.96 CCND1 CDKN2A
8
Show member pathways
11.92 CCND1 ERBB2
9 11.89 CCND1 ERBB2
10 11.89 CCND1 CDKN2A
11
Show member pathways
11.81 CCND1 CDKN2A
12 11.81 CCND1 CDKN2A ERBB2
13 11.79 CCND1 ERBB2
14 11.75 CCND1 CDKN2A
15 11.73 CCND1 ERBB2
16
Show member pathways
11.7 CCND1 ERBB2
17
Show member pathways
11.64 CCND1 ERBB2
18 11.54 CCND1 CDKN2A
19 11.34 CDKN2A ERBB2
20 11.24 CCND1 ERBB2
21
Show member pathways
11.2 CCND1 ERBB2
22 11.19 CCND1 CDKN2A ERBB2
23 11.14 CCND1 CDKN2A
24 10.66 CCND1 CDKN2A ERBB2

GO Terms for Breast Papillomatosis

Biological processes related to Breast Papillomatosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of protein phosphorylation GO:0001934 9.16 CCND1 ERBB2
2 G1/S transition of mitotic cell cycle GO:0000082 8.96 CCND1 CDKN2A
3 negative regulation of immature T cell proliferation in thymus GO:0033088 8.62 CDKN2A ERBB2

Sources for Breast Papillomatosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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