MCID: BRS031
MIFTS: 26

Breast Rhabdomyosarcoma

Categories: Cancer diseases

Aliases & Classifications for Breast Rhabdomyosarcoma

MalaCards integrated aliases for Breast Rhabdomyosarcoma:

Name: Breast Rhabdomyosarcoma 12 15 74
Rhabdomyosarcoma of the Breast 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4060
NCIt 51 C5190
UMLS 74 C1332637

Summaries for Breast Rhabdomyosarcoma

Disease Ontology : 12 A breast sarcoma that arises from skeletal muscle cells.

MalaCards based summary : Breast Rhabdomyosarcoma, also known as rhabdomyosarcoma of the breast, is related to embryonal rhabdomyosarcoma and rhabdomyosarcoma 2. An important gene associated with Breast Rhabdomyosarcoma is MB (Myoglobin), and among its related pathways/superpathways are TNFR1 Pathway and Immune response Function of MEF2 in T lymphocytes. Affiliated tissues include breast and skeletal muscle, and related phenotypes are no phenotypic analysis and respiratory system

Related Diseases for Breast Rhabdomyosarcoma

Diseases related to Breast Rhabdomyosarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 36)
# Related Disease Score Top Affiliating Genes
1 embryonal rhabdomyosarcoma 29.7 MB MYOD1 MYOG
2 rhabdomyosarcoma 2 29.3 MB MYOD1 MYOG
3 rhabdomyosarcoma 28.8 MB MYOD1 MYOG PTPRC
4 orbit rhabdomyosarcoma 10.1 MB MYOG
5 mesenchymoma 10.0 MB MYOD1
6 leiomyosarcoma 10.0 MB MYOG
7 malignant triton tumor 10.0 MB MYOD1
8 botryoid rhabdomyosarcoma 10.0 MB MYOD1
9 gallbladder sarcoma 10.0 MYOD1 MYOG
10 undifferentiated embryonal sarcoma of the liver 10.0 MYOD1 MYOG
11 embryonal sarcoma 10.0 MYOD1 MYOG
12 spindle cell rhabdomyosarcoma 10.0 MB MYOD1
13 rhabdoid cancer 10.0 MB MYOD1
14 inflammatory leiomyosarcoma 10.0 MYOD1 MYOG
15 conventional leiomyosarcoma 10.0 MYOD1 MYOG
16 pleomorphic rhabdomyosarcoma 9.9 MB MYOD1
17 spindle cell liposarcoma 9.9 MYOD1 MYOG
18 gas gangrene 9.9 MB MYOD1
19 nephrogenic adenofibroma 9.9 MYOD1 MYOG
20 kidney rhabdoid cancer 9.9 MB PTPRC
21 extraosseous ewing's sarcoma 9.9 MYOD1 MYOG
22 alveolar soft part sarcoma 9.8 MB MYOD1
23 thymus lipoma 9.8 MB PTPRC
24 immune system organ benign neoplasm 9.8 MB PTPRC
25 muscle tissue disease 9.8 MB MYOD1
26 adult fibrosarcoma 9.7 MB MYOD1 MYOG
27 medullomyoblastoma 9.7 MB MYOD1 MYOG
28 malignant mesenchymoma 9.7 MB MYOD1 MYOG
29 malignant fibroxanthoma 9.7 MYOD1 PTPRC
30 muscle cancer 9.7 MB MYOD1 MYOG
31 skeletal muscle cancer 9.7 MB MYOD1 MYOG
32 rhabdoid tumor predisposition syndrome 1 9.7 MYOD1 PTPRC
33 muscular disease 9.7 MB MYOD1 MYOG
34 myositis 9.6 MB MYOD1
35 histiocytoma 9.5 MB MYOD1 PTPRC
36 ewing sarcoma 9.3 MYOD1 MYOG PTPRC

Graphical network of the top 20 diseases related to Breast Rhabdomyosarcoma:



Diseases related to Breast Rhabdomyosarcoma

Symptoms & Phenotypes for Breast Rhabdomyosarcoma

MGI Mouse Phenotypes related to Breast Rhabdomyosarcoma:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 no phenotypic analysis MP:0003012 9.13 MYOD1 MYOG PTPRC
2 respiratory system MP:0005388 8.92 MB MYOD1 MYOG PTPRC

Drugs & Therapeutics for Breast Rhabdomyosarcoma

Search Clinical Trials , NIH Clinical Center for Breast Rhabdomyosarcoma

Genetic Tests for Breast Rhabdomyosarcoma

Anatomical Context for Breast Rhabdomyosarcoma

MalaCards organs/tissues related to Breast Rhabdomyosarcoma:

42
Breast, Skeletal Muscle

Publications for Breast Rhabdomyosarcoma

Articles related to Breast Rhabdomyosarcoma:

(show all 13)
# Title Authors Year
1
Alveolar Rhabdomyosarcoma of the Breast in Adolescent Female. ( 30454495 )
2018
2
Primary Rhabdomyosarcoma of the Breast: A Report of Two Cases and Literature Review. ( 30286562 )
2018
3
Primary Rhabdomyosarcoma of the Breast: Imaging Findings and Literature Review. ( 30319332 )
2018
4
Primary rhabdomyosarcoma of the breast in a 17-year-old girl: Case report. ( 29245322 )
2017
5
Rhabdomyosarcoma of the Breast in Adolescent and Young Adult (AYA) Women. ( 27879537 )
2017
6
Rhabdomyosarcoma of the breast: Report of a rare malignancy. ( 28795902 )
2017
7
Primary spindle rhabdomyosarcoma of the breast in an adult female. ( 20678130 )
2011
8
A case of primary rhabdomyosarcoma of the breast. ( 23132983 )
2007
9
Primary rhabdomyosarcoma of the breast in a 13-year-old girl: report of a case. ( 17186344 )
2007
10
Rhabdomyosarcoma of the breast. ( 16153540 )
2005
11
Fatal breast rhabdomyosarcoma in a 15 year old primigravida. ( 2379516 )
1990
12
Cytology of fine needle aspiration biopsy of primary breast rhabdomyosarcoma in an adolescent girl. ( 3859144 )
1985
13
Rhabdomyosarcoma of the breast. ( 6893144 )
1980

Variations for Breast Rhabdomyosarcoma

Expression for Breast Rhabdomyosarcoma

Search GEO for disease gene expression data for Breast Rhabdomyosarcoma.

Pathways for Breast Rhabdomyosarcoma

GO Terms for Breast Rhabdomyosarcoma

Cellular components related to Breast Rhabdomyosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transcription factor complex GO:0005667 8.62 MYOD1 MYOG

Biological processes related to Breast Rhabdomyosarcoma according to GeneCards Suite gene sharing:

(show all 14)
# Name GO ID Score Top Affiliating Genes
1 regulation of gene expression GO:0010468 9.54 MYOD1 PTPRC
2 cellular response to tumor necrosis factor GO:0071356 9.52 MYOD1 MYOG
3 muscle organ development GO:0007517 9.51 MYOD1 MYOG
4 skeletal muscle tissue development GO:0007519 9.49 MYOD1 MYOG
5 skeletal muscle cell differentiation GO:0035914 9.48 MYOD1 MYOG
6 cellular response to estradiol stimulus GO:0071392 9.46 MYOD1 MYOG
7 positive regulation of muscle cell differentiation GO:0051149 9.43 MYOD1 MYOG
8 skeletal muscle fiber development GO:0048741 9.4 MYOD1 MYOG
9 positive regulation of myoblast differentiation GO:0045663 9.37 MYOD1 MYOG
10 myoblast differentiation GO:0045445 9.32 MYOD1 MYOG
11 positive regulation of myoblast fusion GO:1901741 9.26 MYOD1 MYOG
12 myotube differentiation GO:0014902 9.16 MYOD1 MYOG
13 positive regulation of skeletal muscle fiber development GO:0048743 8.96 MYOD1 MYOG
14 muscle cell fate commitment GO:0042693 8.62 MYOD1 MYOG

Molecular functions related to Breast Rhabdomyosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein dimerization activity GO:0046983 9.26 MYOD1 MYOG
2 DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228 9.16 MYOD1 MYOG
3 chromatin DNA binding GO:0031490 8.96 MYOD1 MYOG
4 E-box binding GO:0070888 8.62 MYOD1 MYOG

Sources for Breast Rhabdomyosarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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