MCID: BRS061
MIFTS: 33

Breast Sarcoma

Categories: Cancer diseases

Aliases & Classifications for Breast Sarcoma

MalaCards integrated aliases for Breast Sarcoma:

Name: Breast Sarcoma 12 15
Sarcoma of Breast 12 71

Classifications:



External Ids:

Disease Ontology 12 DOID:3017
NCIt 49 C4670
SNOMED-CT 67 278050001
UMLS 71 C0349667

Summaries for Breast Sarcoma

Disease Ontology : 12 A breast cancer that has material basis in abnormally proliferating cells derives from mesenchymal cells.

MalaCards based summary : Breast Sarcoma, also known as sarcoma of breast, is related to breast rhabdomyosarcoma and angiosarcoma. An important gene associated with Breast Sarcoma is TP53 (Tumor Protein P53), and among its related pathways/superpathways are Gastric cancer and Apoptosis Pathway. Affiliated tissues include breast, brain and myeloid, and related phenotypes are behavior/neurological and cellular

Related Diseases for Breast Sarcoma

Diseases related to Breast Sarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 361)
# Related Disease Score Top Affiliating Genes
1 breast rhabdomyosarcoma 32.6 MYOG MOCS2
2 angiosarcoma 30.2 TP53 PECAM1 MYOG CD34
3 benign breast phyllodes tumor 30.1 PGR MME
4 breast osteosarcoma 30.1 PGR MYOG MME KRT5 ERBB2
5 fibrous histiocytoma 30.0 TP53 PECAM1 MYOG CD34
6 liposarcoma 30.0 TP53 PIK3CA MYOG CD34
7 malignant mesenchymoma 29.9 MYOG CD34
8 embryonal sarcoma 29.9 TP53 MYOG
9 leiomyosarcoma 29.7 TP53 PGR PECAM1 MYOG
10 myxofibrosarcoma 29.7 TP53 MYOG CD34
11 hemangiopericytoma, malignant 29.6 PECAM1 MYOG CD34
12 malignant peripheral nerve sheath tumor 29.6 TP53 MYOG CD34
13 breast fibroadenoma 29.3 TP53 PGR MME ERBB2 CD34
14 spindle cell carcinoma 29.2 PGR KRT5 CD34
15 breast angiosarcoma 29.2 SNRK PECAM1 NETO1 CD34
16 carcinosarcoma 29.2 TP53 PIK3CA PGR MME ERBB2
17 breast ductal carcinoma 28.8 TP53 PGR KRT5 ERBB2
18 breast disease 28.8 TP53 PGR KRT5 ERBB2
19 breast metaplastic carcinoma 28.5 PGR MME KRT5 ERBB2
20 breast leiomyosarcoma 11.2
21 breast liposarcoma 11.2
22 breast fibrosarcoma 11.2
23 sarcoma 10.7
24 spindle cell sarcoma 10.7
25 rare head and neck tumor 10.5 TP53 PIK3CA
26 rare adenocarcinoma of the breast 10.5 TP53 PIK3CA
27 benign pleural mesothelioma 10.5 TP53 CD34
28 multifocal osteogenic sarcoma 10.5 TP53 CD34
29 glomangioma 10.5 PECAM1 CD34
30 acanthoma 10.4 TP53 PIK3CA
31 skin epithelioid hemangioma 10.4 PECAM1 CD34
32 aortic malignant tumor 10.4 PECAM1 CD34
33 prostate angiosarcoma 10.4 PECAM1 CD34
34 urethra transitional cell carcinoma 10.4 TP53 PECAM1
35 central nervous system angiosarcoma 10.4 PECAM1 CD34
36 intravascular angioleiomyoma 10.4 PECAM1 CD34
37 heart fibrosarcoma 10.4 PECAM1 CD34
38 central nervous system hemangioma 10.4 PECAM1 CD34
39 ovarian angiosarcoma 10.4 PECAM1 CD34
40 conventional angiosarcoma 10.4 PECAM1 CD34
41 angiomyoma 10.4 PECAM1 CD34
42 gastric papillary adenocarcinoma 10.4 TP53 ERBB2
43 gallbladder leiomyosarcoma 10.4 PECAM1 CD34
44 glomangiosarcoma 10.4 PECAM1 CD34
45 thyroid sarcoma 10.4 PECAM1 CD34
46 bartholin's gland adenoma 10.4 TP53 PGR
47 bartholin's gland benign neoplasm 10.4 TP53 PGR
48 vestibular gland benign neoplasm 10.4 TP53 PGR
49 hemangioma of spleen 10.4 PECAM1 CD34
50 kaposiform hemangioendothelioma 10.4 PECAM1 CD34

Graphical network of the top 20 diseases related to Breast Sarcoma:



Diseases related to Breast Sarcoma

Symptoms & Phenotypes for Breast Sarcoma

MGI Mouse Phenotypes related to Breast Sarcoma:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.97 ERBB2 KRT5 MME MOCS2 MYOG NETO1
2 cellular MP:0005384 9.96 CD34 ERBB2 ITGA4 MME MOCS2 MYOG
3 homeostasis/metabolism MP:0005376 9.85 CD34 ERBB2 MME MOCS2 MYOG PECAM1
4 integument MP:0010771 9.65 CD34 ERBB2 KRT5 MME MOCS2 MYOG
5 muscle MP:0005369 9.23 ERBB2 MOCS2 MYOG PECAM1 PGR PIK3CA

Drugs & Therapeutics for Breast Sarcoma

Search Clinical Trials , NIH Clinical Center for Breast Sarcoma

Genetic Tests for Breast Sarcoma

Anatomical Context for Breast Sarcoma

MalaCards organs/tissues related to Breast Sarcoma:

40
Breast, Brain, Myeloid, Bone, Whole Blood, Lymph Node, Liver

Publications for Breast Sarcoma

Articles related to Breast Sarcoma:

(show top 50) (show all 153)
# Title Authors PMID Year
1
Radiation-induced undifferentiated pleomorphic sarcoma of the breast. 61
32047082 2020
2
Not Otherwise Specified-Type Sarcoma of Breast with CD10 Expression: Case Report. 61
31620687 2019
3
Neoadjuvant chemotherapy for primary sarcoma of the breast: a case report. 61
31488201 2019
4
Primary Rhabdomyosarcoma of the Breast: Study of Three Cases at One Institution with a Review of Primary Breast Sarcomas. 61
31370385 2019
5
Cluster of Differentiation 10 Positive Stromal Sarcoma of Breast: A Diagnostic Challenge. 61
31523571 2019
6
Breast Sarcomas: Experience of a Reference Center in Colombia. 61
31516788 2019
7
Reconstruction options and outcomes for breast sarcoma patients. 61
31025484 2019
8
Primary Stromal Breast Sarcoma with Concomitant Contralateral Carcinoma: A Rare Case from Syria. 61
31583145 2019
9
Malignant Spindle Cell Tumor Breast-a Diagnostic Dilemma. 61
30288003 2018
10
Sarcomas of the Breast. 61
30005780 2018
11
The presence of glutamate residues on the PAS sequence of the stimuli-sensitive nano-ferritin improves in vivo biodistribution and mitoxantrone encapsulation homogeneity. 61
29474961 2018
12
Contribution of de novo and mosaic TP53 mutations to Li-Fraumeni syndrome. 61
29070607 2018
13
Impact of Insurance Coverage on Outcomes in Primary Breast Sarcoma. 61
29736143 2018
14
The Role of Adjuvant Radiotherapy for a Case of Primary Breast Sarcoma: A Plan Comparison between Three Modern Techniques and a Review of the Literature. 61
29849658 2018
15
Advanced Stage Breast Sarcoma Treatment in a Third World Country Public Hospital. 61
30174970 2018
16
Primary Leiomyosarcoma of Breast Presenting with Metastasis: An Atypical Presentation with Dismal Prognosis. 61
29333025 2017
17
Unusual primary breast cancer - malignant peripheral nerve sheath tumor: a case report and review of the literature. 61
28622765 2017
18
Pleomorphic Sarcoma of Breast: A Report of Two Cases and Review of Literature. 61
28532141 2017
19
Imaging findings of primary breast sarcoma: Results of a first multicenter study. 61
28189193 2017
20
[Primary breast sarcomas: About 30 cases treated at Salah-Azaiez institute in Tunisia]. 61
28223032 2017
21
Breast cancer in patients with Li-Fraumeni syndrome - a case-series study and review of literature. 61
28356770 2017
22
Bilateral Myeloid Sarcoma of Breast in a Young Male Occurring after 11 Years of Chronic Myeloid Leukemia Diagnosis: A Unique Pattern of Relapse. 61
27488267 2016
23
Management of Breast Sarcoma. 61
27542642 2016
24
A Scary Onset of a Rare and Aggressive Type of Primary Breast Sarcoma: A Case Report. 61
28101028 2016
25
Primary female breast sarcoma: clinicopathological features, treatment and prognosis. 61
27510467 2016
26
Defining Action Levels for In Vivo Dosimetry in Intraoperative Electron Radiotherapy. 61
26025385 2016
27
Sarcoma of the breast: an update on a rare entity. 61
26729013 2016
28
Primary breast sarcoma: A retrospective study over 35 years from a single institution. 61
26586158 2016
29
Breast sarcoma. A case report and review of literature. 61
27281361 2016
30
Primary Stromal Sarcoma of Breast: A Rare Entity. 61
28974969 2016
31
Early Local Recurrence Presents Adverse Effect on Outcomes of Primary Breast Sarcoma: A Retrospective Study From Single Institute in China. 61
26735546 2016
32
Phyllodes tumours of the breast: a consensus review. 61
26768026 2016
33
Primary leiomyosarcoma of the breast with prominent osteoclastic giant cells: A case expressing receptor activator of NF-κB ligand (RANKL). 61
26150133 2015
34
Giant cell variant of malignant fibrous histiocytoma of male breast: A rare case report. 61
26458656 2015
35
Angiosarcoma in previously irradiated breast in patient with Li-Fraumeni syndrome. A case report. 61
25271877 2015
36
Comparison of the clinical and prognostic features of primary breast sarcomas and malignant phyllodes tumor. 61
25387733 2015
37
Ventricular tachycardia associated with radiation-induced cardiac sarcoma. 61
25593527 2014
38
Optimal management of sarcomas of the breast: an update. 61
24611696 2014
39
Spontaneous Perforation as a First Presentation of Ileal Gastrointestinal Stromal Tumour (GIST) with Synchronous Breast Sarcoma. 61
24995213 2014
40
Breast sarcoma: a rare malignancy. 61
24965425 2014
41
Primary fibrosarcoma of male breast: a rare entity. 61
24959458 2014
42
Huge primary soft tissue sarcoma of the breast on bone scan. 61
24152643 2014
43
Immediate chest wall reconstruction during pregnancy: surgical management after extended surgical resection due to primary sarcoma of the breast. 61
23827451 2014
44
Breast sarcoma after breast-conserving therapy for breast cancer in a patient with Li-Fraumeni syndrome presenting as focal nonmasslike enhancement on MRI. 61
24261401 2013
45
Primary chondrosarcoma of breast. 61
24112268 2013
46
Basophilic round bodies in gastric biopsies little known by pathologists: iatrogenic yttrium 90 microspheres deriving from selective internal radiation therapy. 61
23564705 2013
47
Leiomyosarcoma of the female breast: report of a case. 61
24426525 2013
48
Cytologic diagnosis of undifferentiated high grade pleomorphic sarcoma of breast presenting with brain metastasis. 61
23914101 2013
49
Breast sarcoma. 61
23552541 2013
50
Recurrent phyllodes sarcoma of breast with complete chest wall invasion; a multidisciplinary approach for radical resection. 61
23425565 2013

Variations for Breast Sarcoma

Expression for Breast Sarcoma

Search GEO for disease gene expression data for Breast Sarcoma.

Pathways for Breast Sarcoma

GO Terms for Breast Sarcoma

Biological processes related to Breast Sarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 leukocyte migration GO:0050900 9.46 PIK3CA PECAM1 ITGA4 CD34
2 replicative senescence GO:0090399 9.32 TP53 MME
3 paracrine signaling GO:0038001 9.26 PGR CD34
4 diapedesis GO:0050904 8.96 PECAM1 ITGA4
5 glomerular endothelium development GO:0072011 8.62 PECAM1 CD34

Sources for Breast Sarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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