Brill-Zinsser Disease disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: BRL001 MIFTS: 27	Brill-Zinsser Disease Categories: Infectious diseases, Rare diseases
Genes Related diseases Publications Pathways Drugs Expand all tables

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Aliases & Classifications for Brill-Zinsser Disease

MalaCards integrated aliases for Brill-Zinsser Disease:

Name: Brill-Zinsser Disease ¹² ⁵⁸ ¹⁵ ¹⁷ ⁷¹

Recrudescent Typhus ¹² ⁵⁸

Typhus, Epidemic Louse-Borne ⁴⁴

Brill Zinsser Disease ¹²

Brill's Disease ¹²

Sporadic Typhus ¹²

Latent Typhus ¹²

Brill Disease ⁵⁸

Classifications:

MalaCards categories:
Global: Infectious diseases Rare diseases

See all MalaCards categories (disease lists)

ICD10: ³² ³³

Certain infectious and parasitic diseases

Rickettsioses

Typhus fever

Recrudescent typhus [Brill disease]

Orphanet: ⁵⁸

Rare infectious diseases

External Ids:

Disease Ontology ¹² DOID:11254

ICD9CM ³⁴ 081.1

MeSH ⁴⁴ D014438

SNOMED-CT ⁶⁷ 47761007

ICD10 ³² A75.1

ICD10 via Orphanet ³³ A75.1

UMLS via Orphanet ⁷² C0006181

Orphanet ⁵⁸ ORPHA99990

EFO ¹⁷ EFO_0007182

UMLS ⁷¹ C0006181

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Summaries for Brill-Zinsser Disease

Disease Ontology : ¹² An epidemic typhus that is a mild form of the disease, which recurs in someone after a long period of latency due to immunosuppression, malnutrition or other illnesses.

MalaCards based summary : Brill-Zinsser Disease, also known as recrudescent typhus, is related to epidemic typhus and spotted fever. An important gene associated with Brill-Zinsser Disease is AFF2 (AF4/FMR2 Family Member 2), and among its related pathways/superpathways is Bacterial invasion of epithelial cells. The drugs Doxycycline and Azithromycin have been mentioned in the context of this disorder.

Wikipedia : ⁷⁴ Brill-Zinsser disease is a delayed relapse of epidemic typhus, caused by Rickettsia prowazekii. After a... more...

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Related Diseases for Brill-Zinsser Disease

Diseases related to Brill-Zinsser Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 26)

#	Related Disease	Score	Top Affiliating Genes
1	epidemic typhus	31.2	XRCC6 SPTBN2 PLEKHG4 GLRX5 AFF2
2	spotted fever	30.0	SPTBN2 PLEKHG4 AFF2
3	endemic typhus	29.9	SPTBN2 PLEKHG4 GLRX5 AFF2
4	typhus-group rickettsiosis	10.2
5	exanthem	10.2
6	aseptic meningitis	10.2
7	indian tick typhus	10.2	PLEKHG4 AFF2
8	flinders island spotted fever	10.2	PLEKHG4 AFF2
9	israeli tick typhus	10.2	SPTBN2 PLEKHG4
10	spinocerebellar ataxia 1	10.1	PLEKHG4 AFF2
11	spinocerebellar ataxia 18	10.1	SPTBN2 PLEKHG4
12	cerebellar ataxia type 9	10.1	SPTBN2 PLEKHG4
13	spinocerebellar ataxia 30	10.1	SPTBN2 PLEKHG4
14	rocky mountain spotted fever	10.0	SPTBN2 PLEKHG4 AFF2
15	boutonneuse fever	10.0	SPTBN2 PLEKHG4 AFF2
16	diabetes insipidus	10.0
17	meningitis	10.0
18	far eastern spotted fever	10.0	SPTBN2 GLRX5
19	dentatorubral-pallidoluysian atrophy	9.9	SPTBN2 PLEKHG4 AFF2
20	aggressive systemic mastocytosis	9.9	KRT24 CBL
21	episodic ataxia, type 2	9.9	SPTBN2 CAV2
22	autosomal dominant cerebellar ataxia	9.9	SPTBN2 PLEKHG4 AFF2
23	japanese spotted fever	9.9	PLEKHG4 HSD17B14 AFF2
24	queensland tick typhus	9.8	PLEKHG4 HSD17B14 CAV2
25	jacobsen syndrome	9.8	CBL AFF2
26	cerebellar disease	9.7	XRCC6 SPTBN2 PLEKHG4

Graphical network of the top 20 diseases related to Brill-Zinsser Disease:

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Symptoms & Phenotypes for Brill-Zinsser Disease

Sources

Drugs & Therapeutics for Brill-Zinsser Disease

Drugs for Brill-Zinsser Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 13)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Doxycycline

Approved, Investigational, Vet_approved

Phase 4

564-25-0

54671203

Synonyms:

(2E,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione

(2Z)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione

(2Z,4S,4aR,5S,5aR,6R)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione

(2Z,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione

(4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide

(4S,4AR,5S,5ar,6R,12as)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide

10597-92-9

17086-28-1 (mono-hydrate)

24390-14-5

2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, (4S,4aR,5S,5aR,6R,12aS)

41411-66-9 (6-epimer, mono-hydrochloride)

564-25-0

5-Hydroxy-a-6-deoxytetracycline

5-Hydroxy-alpha-6-deoxytetracycline

5-hydroxy-α-6-deoxytetracycline

5-Hydroxy-α-6-deoxytetracycline

69935-17-7 (mono-hydrochloride, di-hydrate)

6a-Deoxy-5-oxytetracycline

6alpha-deoxy-5-oxytetracycline

6-alpha-deoxy-5-oxytetracycline

6alpha-Deoxy-5-oxytetracycline

6-alpha-Deoxy-5-oxytetracycline

6-Deoxyoxytetracycline

6-Deoxytetracycline

6α-deoxy-5-oxytetracycline

6Α-deoxy-5-oxytetracycline

7164-70-7

7264-10-0

94088-85-4 (calcium salt (1:2))

AB08 (*Fosfatex)

AC1NQXW7

AC1NS4CW

AC1NUYS8

AC1O8PYM

alpha-6-Deoxy-5-hydroxytetracycline

alpha-6-Deoxyoxytetracycline

alpha-Doxycycline

Alti-Doxycycline

Anhydrous doxycycline

Apo-Doxy

Atridox

Azudoxat

BCBcMAP01_000024

BIDD:GT0146

BMY-28689

BPBio1_000951

BSPBio_000863

BSPBio_001936

BU-3839T

C06973

CHEBI:50845

CHEMBL1433

CID5281011

CID5353597

CID5463943

CID6713981

CPD001550033

D07876

DB00254

Deoxymykoin

DivK1c_000345

DMSC (*Fosfatex)

Dossiciclina

Dossiciclina [DCIT]

Doxcycline anhydrous

DOXCYCLINE ANHYDROUS

Doxiciclina

Doxiciclina [INN-Spanish]

Doxiciclina [Italian]

Doxitard

Doxivetin

DOXY

Doxy-Caps

Doxycen

Doxychel

Doxychel (TN)

Doxycin

Doxycyclin

doxycycline

Doxycycline

Doxycycline (200mg/day) or Placebo

Doxycycline (anhydrous)

Doxycycline (INN)

Doxycycline (internal use)

Doxycycline (TN)

Doxycycline anhydrous

DOXYCYCLINE CALCIUM

Doxycycline hyclate

Doxycycline monohydrate

DOXYCYCLINE MONOHYDRATE

Doxycycline-Chinoin

Doxycyclinum

Doxycyclinum [INN-Latin]

Doxy-Puren

Doxysol

Doxy-Tabs

Doxytec

Doxytetracycline

EINECS 209-271-1

GS-3065 (*monohydrate)

HMS2090E06

HSDB 3071

Hydramycin

IDI1_000345

Investin

Jenacyclin

KBio1_000345

KBio2_001287

KBio2_003855

KBio2_006423

KBio3_001156

KBioGR_001133

KBioSS_001287

Liviatin

Lopac0_000405

LS-187766

LS-93868

MolPort-002-507-423

Monodox

Monodox (*monohydrate)

NCGC00161602-01

NCGC00161602-03

NCGC00161602-04

NCGC00167961-01

NCGC00179395-01

NINDS_000345

Novo-Doxylin

NSC633557

Nu-Doxycycline

Oracea

Prestwick0_000852

Prestwick1_000852

Prestwick2_000852

Prestwick3_000852

Ronaxan

SAM002589932

SMP1_000107

Spanor

SPBio_000246

SPBio_002784

Spectrum_000807

Spectrum2_000143

Spectrum3_000408

Spectrum4_000527

Spectrum5_000947

STOCK1N-34341

Supracyclin

UNII-334895S862

UPCMLD-DP021

UPCMLD-DP021:001

Vibramycin

Vibramycin (*monohydrate)

Vibramycin Novum

Vibramycine

Vibra-tabs

Vibravenos

Vivox (*Hyclate)

Azithromycin

Approved

Phase 4

83905-01-5

55185 447043

Synonyms:

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)13-((2,6-Dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-1-oxa-6-azacyclopentadecan-15-one

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-((2,6-Dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-1-oxa-6-azacyclopentadecan-15-one

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)13-((2,6-Dideoxy-3-C-methyl-3-O-methyl-a-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-b-D-xylo-hexopyranosyl)oxy)-1-oxa-6-azacyclopentadecan-15-one

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)13-((2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl)oxy)-1-oxa-6-azacyclopentadecan-15-one

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-{[3,4,6-trideoxy-3-(dimethylamino)-b-D-xylo-hexopyranosyl]oxy}-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-a-L-ribo-hexopyranoside

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-{[3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl]oxy}-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside

121470-24-4

1-Oxa-6-azacyclopentadecan-15-one, 13-((2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-,(2R-(2R*,3S*

75199_FLUKA

83905-01-5

9-Deoxo-9a-aza-9a-methyl-9a-homoerythromycin A

AC-16014

AC1L9KEG

Aritromicina

Azadose

Azasite

Azenil

Azifast

Azigram

Azimakrol

Azithramycine

azithromycin

Azithromycin

Azithromycin & Tumor Necrosis Factor

Azithromycin (AIDS Initiative)

Azithromycin (anhydrous)

Azithromycin dihydrate

Azithromycin monohydrate

Azithromycin Monohydrate

Azithromycin pfizer brand

Azithromycine

Azithromycinum

Azitrocin

Azitromax

Azitromicina

Azitromin

Azythromycin

Bayer brand OF azithromycin dihydrate

BIDD:GT0792

Bio-0676

BRN 5387583

BSPBio_002285

C38H72N2O12

CCRIS 1961

CHEBI:2955

CHEMBL529

CID447043

CP62,993

CP-62993

CPD000471864

DCH3

Dihydrate, azithromycin

DivK1c_000233

DRG-0104

Funk brand OF azithromycin dihydrate

Goxal

Hemomycin

HMS1922G12

HMS2094M11

HMS500L15

HSDB 7205

IDI1_000233

KBio1_000233

KBio2_000787

KBio2_003355

KBio2_005923

KBio3_001505

KBioGR_000731

KBioSS_000787

Lesvi brand OF azithromycin dihydrate

LS-1834

Mack brand OF azithromycin dihydrate

Misultina

MLS001055353

MLS001066331

MLS001201763

MLS001304005

MLS001332499

MLS001332500

MolPort-002-507-426

Monohydrate, azithromycin

NCGC00090753-01

NCGC00090753-02

NINDS_000233

NSC643732

Pfizer brand OF azithromycin

Pfizer brand OF azithromycin dihydrate

Pharmacia brand OF azithromycin dihydrate

SAM002589961

SMR000471864

SPBio_001544

Spectrum_000307

SPECTRUM1503679

Spectrum2_001582

Spectrum3_000653

Spectrum4_000186

Spectrum5_001867

Sumamed

Toraseptol

Tromix

Ultreon

UNII-JTE4MNN1MD

Vinzam

Vita brand OF azithromycin dihydrate

XZ-450

Zentavion

ZIT

Zithromac

Zithromax

Zithromax IV

Zithromycin

Zitromax

Zitromax Avium 600

Zmas

Zmax

Z-Pak

Anti-Infective Agents

Phase 4

Antiparasitic Agents

Phase 4

Antiprotozoal Agents

Phase 4

Anti-Bacterial Agents

Phase 4

Antimalarials

Phase 4

Antibiotics, Antitubercular

Phase 4

Telithromycin

Approved

Phase 3

191114-48-4

5462516 70789201

Synonyms:

(1R,2R,4R,6R,7R,8R,10R,13R,14S)-7-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-13-ethyl-6-methoxy-2,4,6,8,10,14-hexamethyl-17-[4-(4-pyridin-3-ylimidazol-1-yl)butyl]-12,15-dioxa-17-azabicyclo[12.3.0]heptadecane-3,9,11,16-tetrone

(1R,2R,4R,6R,7R,8R,10S,13R,14S)-7-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-13-ethyl-6-methoxy-2,4,6,8,10,14-hexamethyl-17-[4-(4-pyridin-3-ylimidazol-1-yl)butyl]-12,15-dioxa-17-azabicyclo[12.3.0]heptadecane-3,9,11,16-tetrone

(1R,2R,4R,6S,7R,8R,10R,13R,14S)-7-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-13-ethyl-6-methoxy-2,4,6,8,10,14-hexamethyl-17-[4-(4-pyridin-3-ylimidazol-1-yl)butyl]-12,15-dioxa-17-azabicyclo[12.3.0]heptadecane-3,9,11,16-tetrone

(1R,2S,4R,6R,7R,8R,10R,13R,14S)-7-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-13-ethyl-6-methoxy-2,4,6,8,10,14-hexamethyl-17-[4-(4-pyridin-3-ylimidazol-1-yl)butyl]-12,15-dioxa-17-azabicyclo[12.3.0]heptadecane-3,9,11,16-tetrone

(3R,5S,6S,7R,8S,11S,12R,13S,14R,15S)-12- [(4-O-ACETYL-2,6-DIDEOXY-3-O-METHYL-ALPHA-L-ARABINO-HEXOPYRANOSYL) OXY] -14-{[2-O-ACETYL-3,4,6-TRIDEOXY-3-(DIMETHYLAMINO) BETA-D-XYLO-HEXOPYRANOSYL]OXY} -5,7,8,11,13,15-HEXAMETHYL-4,10-DIOXO-1,9-DIOXASPIRO[2.13]HEXADEC-6-YL ACETATE

11,12-Dideoxy-3-des(2,6-dideoxy-3-C,3-O-dimethyl-alpha-L-altropyranosyloxy)-6-O-methyl-3-oxo-12,11-(oxycarbonylimino)-N11-[4-[4-(3-pyridyl)imidazol-1-yl]butyl]erythromycin A

173838-31-8

191114-48-4

AC-1692

AC1L2K8V

AC1MHE79

AC1NUWEH

AC1NUZ37

C12009

CHEBI:46029

CHEMBL1136

CHEMBL1215848

CHEMBL1236249

CID11693521

CID3002190

CID5462516

CID5496803

CID9918852

CPD000469222

D01078

DB00976

HMR 3647

HMR3647

HMR-3647

HMS2052B11

HSDB 7359

Ketek

Ketek (TN)

Levviax

LS-182988

MolPort-005-935-303

MolPort-006-666-261

NCGC00167967-01

RU 66647

RU66647

RU-66647

SAM001246805

TEL

telithromycin

Telithromycin

Telithromycin (JAN/USAN/INN)

Telithromycin [USAN:BAN:INN]

telitromicina

UNII-KI8H7H19WL

Rifampicin

Approved

13292-46-1

5458213 5381226

Synonyms:

13292-46-1

1-b]furan-21-yl acetate

3-(((4-Methyl-1-piperazinyl)imino)-methyl)rifamycin

3-(((4-Methyl-1-piperazinyl)imino)methyl)rifamycin SV

3-([(4-Methyl-1-piperazinyl)imino]methyl)rifamycin SV

3-(4-Methylpiperazinyliminomethyl)rifamycin SV

3-(4-Methylpiperazinyliminomethyl)-rifamycin SV

3-[(4-Methyl-1-piperazinyl)iminomethyl]rifamycin SV

3-[[(4-Methyl-1-piperazinyl)imino]-methyl]rifamycin

46713_FLUKA

46713_RIEDEL

62534-43-4

8-(((4-Methyl-1-piperazinyl)imino)methyl)rifamycin SV

8-(4-Methylpiperazinyliminomethyl) rifamycin SV

8-[[(4-Methyl-1-piperazinyl)imino[methyl]rifamycin

8-[[(4-Methyl-1-piperazinyl)imino]methyl]rifamycin sv

8-[[(4-Methylpiperazinyl)imino]methyl]rifamycin sv

83907_FLUKA

83907_SIGMA

8CI)

Abrifam

Archidyn

Arficin

Arzide

AZT + Rifampin

Ba 41166

Ba 41166/E

BA-41166E

Benemicin

Benemycin

BIDD:PXR0014

Bio-0621

BPBio1_000561

BSPBio_000509

C06688

C43H58N4O12

CAS-13292-46-1

CCRIS 551

CHEBI:28077

CHEBI:455936

CHEMBL180

CID5381226

CID5388984

CID5458213

CID5702112

CID6604339

CID6708473

CID6842115

CID6912767

CID6913622

CPD001906767

D00211

DB01045

Dione 21-acetate

Dipicin

DivK1c_000550

Doloresum

DRG-0109

EINECS 236-312-0

Eremfat

Famcin

Fenampicin

HMS1569J11

HMS1920P08

HMS2089F12

HMS2092G09

HMS501L12

HSDB 3181

KBio1_000550

KBio2_000919

KBio2_003487

KBio2_006055

KBio3_003018

KBioGR_001780

KBioSS_000919

L-5103

L-5103 Lepetit

LS-7689

MLS000028552

MLS001148237

MLS001333745

MolPort-000-767-051

MolPort-002-513-586

MolPort-003-666-281

MolPort-006-395-891

NCGC00016699-01

NCGC00017365-01

NCGC00018178-01

NCGC00022678-03

NCGC00022678-04

NCGC00022678-05

NCGC00160500-01

nchembio884-comp4

NCI60_000309

NINDS_000550

NSC 113926

NSC113926

NSC-113926

Piperine & Rifampicin

Prestwick_833

Prestwick0_000525

Prestwick1_000525

Prestwick2_000525

Prestwick3_000525

R/AMP

R0079

R3501_SIAL

R3501_SIGMA

R5777_SIGMA

R7382_SIGMA

Ramp

RAMP

R-Cin

Reserpine & Rifampicin

Rfamipicin

RFP

Rifa

Rifadin

Rifadin (TN)

Rifadin I.V

Rifadin I.V.

Rifadin Iv

Rifadin IV

Rifadin, Rimactane, Rifampicin, Rifampin

Rifadine

Rifagen

Rifaldazin

Rifaldazine

Rifaldin

Rifam

Rifamicin AMP

Rifamor

Rifampicin

Rifampicin & EEP

Rifampicin & Propolis

Rifampicin (JP15/INN)

Rifampicin [INN:BAN:JAN]

Rifampicin SV

Rifampicina

Rifampicina [INN-Spanish]

Rifampicine

Rifampicine [French]

Rifampicinum

Rifampicinum [INN-Latin]

rifampin

Rifampin

Rifampin (USP)

Rifampin [USAN]

Rifamsolin

Rifamycin

Rifamycin Amp

Rifamycin AMP

Rifaprodin

Rifcin

Rifinah

Rifobac

Rifoldin

Rifoldine

Riforal

Rimactan

Rimactane

Rimactane (TN)

Rimactazid

Rimactin

Rimactizid

Rimazid

Rimycin

RMP

Rofact

S1764_Selleck

SAM002264646

Sinerdol

SMR000058322

SMR000653525

SPBio_002430

Spectrum_000439

SPECTRUM1500529

Spectrum3_001837

Spectrum4_001250

Spectrum5_002018

STK080143

TNP00313

Tubocin

UNII-VJT6J7R4TR

WLN: V1 WQ A&1 E&1 E1UN- AT6N DNTJ D1

Ethanol

Approved

64-17-5

702

Synonyms:

(C6-C9)Alkyl alcohol

[CH2Me(OH)]

[OEtH]

02483_FLUKA

02851_FLUKA

02853_FLUKA

02854_FLUKA

02855_FLUKA

02856_FLUKA

02856_SIAL

02857_FLUKA

02857_SIAL

02858_FLUKA

02858_SIAL

02860_FLUKA

02865_FLUKA

02865_SIAL

02870_FLUKA

02870_SIAL

02875_FLUKA

02877_FLUKA

02878_FLUKA

02882_FLUKA

02882_SIAL

02883_FLUKA

02884_FLUKA

02890_FLUKA

02890_SIAL

02891_FLUKA

02891_SIAL

100C.NPA

121182-78-3

187380_ALDRICH

187380_SIAL

1-Hydroxyethane

24102_RIEDEL

24102_SIAL

24103_RIEDEL

24103_SIAL

24105_RIEDEL

24105_SIAL

24106_RIEDEL

24106_SIAL

24194_RIEDEL

24194_SIAL

245119_ALDRICH

245119_SIAL

270741_ALDRICH

270741_SIAL

277649_ALDRICH

277649_SIAL

2858_SIGMA

29221_FLUKA

32205_RIEDEL

32205_SIAL

32221_RIEDEL

32221_SIAL

32294_RIEDEL

32294_SIAL

34870_SIAL

34963_RIEDEL

39278_FLUKA

40210_ALDRICH

40210_RIEDEL

41322_FLUKA

458600_ALDRICH

458600_SIAL

459828_ALDRICH

459828_SIAL

459836_ALDRICH

459836_SIAL

459844_SIAL

48075_SUPELCO

493511_SIAL

493538_ALDRICH

493538_SIAL

493546_ALDRICH

493546_SIAL

64-17-5

676829_SIAL

68475-56-9

71076-86-3

71329-38-9

8000-16-6

8024-45-1

absolute alcohol

Absolute alcohol

Absolute Alcohol

Absolute ethanol

Absolute Ethanol

Absolute ethyl alcohol

AC1L19TW

AC1Q31MM

Aethanol

Aethanol [German]

Aethylalkohol

AHD 2000

AI3-01706

Alcare hand degermer

Alcare Hand Degermer

alcohol

Alcohol

Alcohol (ethyl)

Alcohol (USP)

Alcohol [USP]

ALCOHOL 5% IN D5-W

Alcohol anhydrous

Alcohol Anhydrous

Alcohol dehydrated

Alcohol denatured

alcohol etilico

Alcohol etilico

Alcohol etílico

Alcohol, absolute

Alcohol, Absolute

Alcohol, anhydrous

Alcohol, dehydrated

Alcohol, Dehydrated

Alcohol, denatured

Alcohol, diluted

Alcohol, Diluted

Alcohol, ethyl

Alcohol, grain

Alcohol, Grain

Alcohols

Alcohols, C1-3

Alcohols, C30

Alcohols, C6-9

Alcool ethylique

Alcool Ethylique

Alcool éthylique

Alcool etilico

Alcool Etilico

Algrain

Alkohol

Alkohol [German]

Alkoholu etylowego

Alkoholu Etylowego

Aminoethanol

Anhydrol

Anhydrol PM 4085

Anhydrous alcohol

Anhydrous ethanol

Äthanol

Äthylalkohol

Beta-Aminoethanol

Beta-Aminoethyl Alcohol

Beta-Ethanolamine

Beta-Hydroxyethylamine

bmse000297

C00469

C2H5OH

C2H6O

Caswell No. 426

Caswell No. 430

CCRIS 945

CDA 19

CDA 19-200

CHEBI:16236

CHEMBL545

CID702

Colamine

Cologne spirit

Cologne Spirit

Cologne spirits

D000431

D00068

DB00898

Dehydrated alcohol

Dehydrated ethanol

Dehydrated Ethanol

Denatured alcohol

Denatured Alcohol

Denatured Alcohol Cd-10

Denatured Alcohol Cd-5

Denatured Alcohol Cd-5a

Denatured Alcohol Sd-1

Denatured Alcohol Sd-13a

Denatured Alcohol Sd-17

Denatured Alcohol Sd-23a

Denatured Alcohol Sd-28

Denatured Alcohol Sd-30

Denatured Alcohol Sd-39b

Denatured Alcohol Sd-39c

Denatured Alcohol Sd-3a

Denatured Alcohol Sd-40m

Denatured ethanol

Denatured Ethanol

Desinfektol el

Desinfektol EL

Diluted alcohol

Distilled spirits

E2385_SIGMA

E7023_ALDRICH

E7023_SIAL

E7148_ALDRICH

E7148_SIAL

E7517_SIGMA

EINECS 200-578-6

EINECS 270-649-4

Envision Conditioner Pdd 9020

EOH

EOX

Esumiru WK 88

ETA

etanol

Etanol

Etanolo

Etanolo [Italian]

ethanol

éthanol

Ethanol (9CI)

Ethanol [JAN]

Ethanol 200 proof

Ethanol 200 Proof

Ethanol Absolute

Ethanol Absolute Bp

Ethanol Anhydrous

Ethanol Extra Pure

Ethanol solution

Ethanol Vapor

Ethanol, Silent Spirit

Ethanol, undenatured

Ethanolum anhydricum

Ethicap

Ethyl alc

ethyl alcohol

Ethyl alcohol

Ethyl Alcohol

Ethyl Alcohol & Water, 10%

Ethyl Alcohol & Water, 20%

Ethyl Alcohol & Water, 30%

Ethyl Alcohol & Water, 40%

Ethyl Alcohol & Water, 5%

Ethyl Alcohol & Water, 50%

Ethyl Alcohol & Water, 60%

Ethyl Alcohol & Water, 70%

Ethyl Alcohol & Water, 80%

Ethyl Alcohol & Water, 95%

Ethyl Alcohol & Water, 96%

Ethyl alcohol anhydrous

Ethyl Alcohol Anhydrous

Ethyl alcohol in alcoholic beverages

Ethyl alcohol usp

Ethyl Alcohol, Anhydrous

Ethyl Alcohol, Denatured

Ethyl hydrate

Ethyl Hydrate

Ethyl hydroxide

Ethyl Hydroxide

Ethylalcohol

Ethylalcohol [Dutch]

Ethylol

Ethylolamine

Ethyloxy Group

EtOH

Etylowy alkohol

FEMA No. 2419

FEMA Number 2419

Fermentation alcohol

Glycinol

grain alcohol

Grain alcohol

Hinetoless

HSDB 531

HSDB 82

Hydroxyethane

HYDROXYETHYL GROUP

I14-12648

IMS 99

Infinity pure

Infinity Pure

Jaysol

Jaysol S

LS-1539

LTBB002977

Lux

Methylated spirit

Methylated Spirit Mineralised

Methylcarbinol

Molasses alcohol

MolPort-001-785-844

NCGC00091458-01

nchem.651-comp3c

nchembio.552-comp10

nchembio.94-comp20

NCI-C03134

NSC 85228

NSC85228

Oxydimethylene Group

Potato alcohol

Punctilious ethyl alcohol

Pyro

QMHAIh@

Reagent Alcohol

Ru-Tuss Expectorant

SDA 3A

SDA 40-2

SDM No. 37

Sekundasprit

Silent spirit

Spirit

Spirits of wine

Spirits OF wine

spiritus vini

Spiritus vini

Spirt

SY Fresh M

Synasol

Tecsol

Tecsol C

Thanol

Thiofaco M-50

Undenatured ethanol

UNII-3K9958V90M

USAF EK-1597

WLN: Q2

Antitubercular Agents

Vaccines

Interventional clinical trials:

#	Name	Status	NCT ID	Phase	Drugs
1	The Scrub Typhus Antibiotic Resistance Trial (START) Comparing Doxycycline and Azithromycin Treatment Modalities in Areas of Reported Antimicrobial Resistance for Scrub Typhus	Recruiting	NCT03083197	Phase 4	Doxycycline 7 days;Doxycycline 3 days;Azithromycin 3 days
2	Phase 3 Study of Controlled Trial: 5-day Course of Telithromycin Versus Doxycycline for the Treatment of Mild to Moderate Scrub Typhus	Completed	NCT00351182	Phase 3	Telithromycin;Doxycycline
3	The Clinical Epidemiology of Scrub Typhus in Humans, Chiggers and Rodents	Unknown status	NCT02876367
4	Controlled Trial: 5-day Course of Rifampin Versus Doxycycline for the Treatment of Mild to Moderate Scrub Typhus	Completed	NCT00568711		doxycycline;rifampin
5	The Natural Immune Response In Pediatric Scrub Typhus In Chiangrai	Completed	NCT02398162
6	A Multicentre Observational Study to Describe the Prevalence of Scrub Typhus Defined as a Positive Rapid Diagnostic Test Among Selected Patients Presenting With Fever to Clinics in Myanmar	Completed	NCT03269266
7	Prediction and Early Diagnosis for Cardiovascular Disease Complicated by Scrub Typhus Infection	Recruiting	NCT03274869
8	Eschar Investigations to Improve Diagnostics, Understand Early Immune Responses and Characterize Strains for Vaccines in Scrub Typhus	Recruiting	NCT02915861
9	The Epidemiology Of Scrub Typhus And Rickettsial Infections In A Highly Endemic Rural Setting In South India: Population-Based Cohort Study	Recruiting	NCT04506944

Search NIH Clinical Center for Brill-Zinsser Disease

Cochrane evidence based reviews: typhus, epidemic louse-borne

Sources

Genetic Tests for Brill-Zinsser Disease

Sources

Anatomical Context for Brill-Zinsser Disease

Sources

Publications for Brill-Zinsser Disease

Articles related to Brill-Zinsser Disease:

(show top 50) (show all 51)

#	Title	Authors	PMID	Year
1	Rickettsiae and rickettsial diseases in Croatia: Implications for travel medicine. ⁶¹	Dzelalija B...Dobec M	27404664	2016
2	Brill-Zinsser disease in Moroccan man, France, 2011. ⁶¹	Faucher JF...Hoen B	22261378	2012
3	Plant extracts, isolated phytochemicals, and plant-derived agents which are lethal to arthropod vectors of human tropical diseases--a review. ⁶¹	Pohlit AM...Neto VF	21432748	2011
4	Brill-Zinsser disease in a patient following infection with sylvatic epidemic typhus associated with flying squirrels. ⁶¹	McQuiston JH...Urbanowski JC	20687836	2010
5	Adipose tissue serves as a reservoir for recrudescent Rickettsia prowazekii infection in a mouse model. ⁶¹	Bechah Y...Raoult D	20049326	2010
6	Epidemic typhus. ⁶¹	Bechah Y...Raoult D	18582834	2008
7	[Sanitary conditions, health care and epidemiological situation of infectious diseases in Cracow in the period of Galicia autonomy (since 60ties/70ties of 19th century until 1914)]. ⁶¹	Berner W	18536242	2008
8	Rickettsial diseases in Russia. ⁶¹	Tarasevich IV...Mediannikov OY	17114680	2006
9	Eradication of typhus exanthematicus in Bosnia and Herzegovina. ⁶¹	Puvacic Z...Hamzic S	16533184	2006
10	Epidemiological characteristics of rickettsial diseases in Croatia. ⁶¹	Mulic R...Alambasic K	16532877	2006
11	Seroepidemiology of spotted fever group and typhus group rickettsioses in humans, South Korea. ⁶¹	Jang WJ...Kim IS	15665449	2005
12	[The Brill-Zinsser disease still occurs in Croatia: retrospective analysis of 25 hospitalized patients]. ⁶¹	Turcinov D...Puljiz I	12619436	2002
13	Brill-Zinsser disease. ⁶¹	Lutwick LI	11323068	2001
14	Failure of azithromycin in treatment of Brill-Zinsser disease. ⁶¹	Turcinov D...Herendic B	10817744	2000
15	[Brill-Zinsser disease]. ⁶¹	Aoki N	11212755	2000
16	Brill-Zinsser disease in France. ⁶¹	Stein A...Raoult D	10371575	1999
17	[Brill-Zinsser disease]. ⁶¹	Aoki N	10201198	1999
18	Serological response of patients suffering from primary and recrudescent typhus: comparison of complement fixation reaction, Weil-Felix test, microimmunofluorescence, and immunoblotting. ⁶¹	Eremeeva ME...Raoult D	7496969	1994
19	Epidemiology of rickettsial diseases. ⁶¹	Walker DH...Fishbein DB	1884775	1991
20	[The clinical spectrum of rickettsiosis in the area of Zadar]. ⁶¹	Dzelalija B...Dujella J	2398776	1990
21	[An indirect solid-phase immunoenzyme method in diagnosing rickettsial infections]. ⁶¹	Iablonskaia VA...Kuznetsova AV	2485298	1989
22	Brill-Zinsser disease in North America. ⁶¹	Reilly PJ...Kalinske RW	7347050	1980
23	Serologic diagnosis of epidemic typhus fever. ⁶¹	Ormsbee R...Wright L	403761	1977
24	[Brill-Zinsser disease in the region of East Slovakia (author's transl)]. ⁶¹	Mittermayer T	858075	1977
25	[An unusual case of the Brill-Zinsser disease (author's transl)]. ⁶¹	Zambeli M	940412	1976
26	[Data on the use of serological tests for differentiation of exanthematous typhus primary infection from that of recurrences in native cases of Brill-Zinsser disease]. ⁶¹	Cracea E...Buzdugan I	128091	1975
27	Brill-Zinsser disease: report of a case in Canada. ⁶¹	Portnoy J...Clecner B	4841839	1974
28	[Current results and methods in eradication of typhus fever on the Serbian territory excluding autonomic provinces]. ⁶¹	Borjanovic S...Grujicic S	4464479	1974
29	Fluorescent antibody complement fixation test as a serodiagnostic method in the Brill-Zinsser disease. ⁶¹	Zarnea G...Mihancea N	4124598	1972
30	Recrudescent typhus: fluctuations in titers of complement-fixing and microagglutinating antibodies to rickettsia prowazeki in persons with a history of epidemic typhus. ⁶¹	Klingberg W...Goldwasser RA	25607582	1970
31	[Brill-Zinsser disease--presentation of six patients]. ⁶¹	Tudoric G	5206665	1970
32	Incidence of Brill-Zinsser disease in East Slovakia in 1956-1967. ⁶¹	Milosovicova A...Lukacsova V	4992900	1970
33	[Brill Zinsser disease. (Clinical analysis of our cases)]. ⁶¹	Kaljalovic R...Letica Z	5954659	1966
34	[Contributions to the study of serological diagnosis methods in rickettsioses. I. Microagglutination of rickettsia in the diagnosis of relapsing typhus (Brill-Zinsser disease)]. ⁶¹	Zarnea G...Ianopol L	5967206	1966
35	[Contribution to the study of serological diagnostic methods in rickettsioses. II. Passive hemagglutination in the diagnosis of relapsing typhus (Brill-Zinsser disease)]. ⁶¹	Zarnea G...Mardare T	5967207	1966
36	The natural history of recrudescent typhus (Brill-Zinsser disease) in Bosnia. ⁶¹	Gaon JA...Murray ES	5296997	1966
37	DIFFERENTIATION OF 19S AND 7S COMPLEMENT FIXING ANTIBODIES IN PRIMARY VERSUS RECRUDESCENT TYPHUS BY EITHER ETHANETHIOL OR HEAT. ⁶¹	MURRAY ES...GAON JA	14297874	1965
38	SEROLOGIC STUDIES OF PRIMARY EPIDEMIC TYPHUS AND RECRUDESCENT TYPHUS (BRILL-ZINSSER DISEASE). II. DIFFERENCES IN IMMUNOELECTROPHORETIC PATTERNS, RESPONSE TO 2-MERCAPTOETHANOL AND RELATIONSHIPS TO 19 S AND 7 S ANTIBODIES. ⁶¹	MURRAY ES...GAON JA	14296294	1965
39	SEROLOGIC STUDIES OF PRIMARY EPIDEMIC TYPHUS AND RECRUDESCENT TYPHUS (BRILL-ZINSSER DISEASE). I. DIFFERENCES IN COMPLEMENT-FIXING ANTIBODIES: HIGH ANTIGEN REQUIREMENT AND HEAT LABILITY. ⁶¹	MURRAY ES...MULAHASANOVIC M	14296293	1965
40	[Brill-Zinsser disease]. ⁶¹	BINDER L...LEVAI J	13968310	1963
41	[On the problem of Brill-Zinsser disease (with a case report)]. ⁶¹	EMRICH D...REIMOLD G	13890149	1961
42	[Contribution to clinical aspects and diagnosis of Brill-Zinsser disease]. ⁶¹	DEMETER K...TOTH S	13721745	1961
43	[Contribution to the epidemiological role of Brill-Zinsser disease in the area of endemic typhus. A focus of disease produced by a patient in the recurrent stage (morbus Brill-Zinsser)]. ⁶¹	DORDEVIC D...PETKOVIC B	13817644	1959
44	[A rare clinical form of Brill-Zinsser disease]. ⁶¹	TEFTEDARIJA M	13837267	1959
45	BRILL-ZINSSER disease. ⁶¹		13612156	1958
46	Brill-Zinsser disease; the possibility of its occurrence in Britain. ⁶¹	LAWY HS...BENSTED HJ	13587985	1958
47	[Brill-Zinsser disease in the Kosice region]. ⁶¹	MITTERMAYER T...KRATOCHVIL I	13537009	1958
48	Another case of Brill-Zinsser disease in Britain. ⁶¹	STEEL M...LAWY HS	13347109	1956
49	Recrudescent typhus (Brill's disease). ⁶¹	WILT JC...GEMMELL JP	13260998	1955
50	[Recurrent typhus; Brill-Zinsser disease; incidence, epidemiology and clinical aspects in our country]. ⁶¹	GAON J	13347647	1955

Sources

Genes for Brill-Zinsser Disease

Genes related to Brill-Zinsser Disease (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	AFF2	AF4/FMR2 Family Member 2	Protein Coding	6.7	DISEASES inferred ¹⁵
2	SPTBN2	Spectrin Beta, Non-Erythrocytic 2	Protein Coding	5.7	DISEASES inferred ¹⁵
3	PLEKHG4	Pleckstrin Homology And RhoGEF Domain Containing G4	Protein Coding	5.55	DISEASES inferred ¹⁵
4	KRT24	Keratin 24	Protein Coding	5.06	DISEASES inferred ¹⁵
5	CAV2	Caveolin 2	Protein Coding	4.91	DISEASES inferred ¹⁵
6	CBL	Cbl Proto-Oncogene	Protein Coding	4.81	DISEASES inferred ¹⁵
7	GLRX5	Glutaredoxin 5	Protein Coding	4.81	DISEASES inferred ¹⁵
8	HSD17B14	Hydroxysteroid 17-Beta Dehydrogenase 14	Protein Coding	4.75	DISEASES inferred ¹⁵
9	XRCC6	X-Ray Repair Cross Complementing 6	Protein Coding	4.67	DISEASES inferred ¹⁵
10	PCGF5	Polycomb Group Ring Finger 5	Protein Coding	4.66	DISEASES inferred ¹⁵

Sources

Variations for Brill-Zinsser Disease

Sources

Expression for Brill-Zinsser Disease

Search GEO for disease gene expression data for Brill-Zinsser Disease.

Sources

Pathways for Brill-Zinsser Disease

Pathways related to Brill-Zinsser Disease according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Bacterial invasion of epithelial cells ³⁶	10.51	CBL CAV2

Sources

GO Terms for Brill-Zinsser Disease

Sources

Sources for Brill-Zinsser Disease

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ EFO

¹⁸ ExPASy

¹⁹ FMA

²⁰ GARD

²¹ GeneAnalytics

²² GeneCards

²³ GeneGo (Thomson Reuters)

²⁴ GeneHancer via GeneCards

²⁵ GeneReviews

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HMDB

³¹ HPO

³² ICD10

³³ ICD10 via Orphanet

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ KEGG

³⁷ LifeMap

³⁸ LncRNADisease

³⁹ LOVD

⁴⁰ MalaCards

⁴¹ MedGen

⁴² MedlinePlus

⁴³ MedlinePlus Genetics

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NINDS

⁵⁴ Novoseek

⁵⁵ Novus Biologicals

⁵⁶ OMIM via Orphanet

⁵⁷ OMIM® (Updated 05-Mar-2021)

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubMed

⁶² PubMed Health

⁶³ QIAGEN

⁶⁴ R&D Systems

⁶⁵ Reactome

⁶⁶ Sino Biological

⁶⁷ SNOMED-CT

⁶⁸ SNOMED-CT via HPO

⁶⁹ TGDB

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ Wikipedia