MCID: BRN053
MIFTS: 25

Bronchial Adenomas/carcinoids Childhood

Categories: Cancer diseases, Rare diseases

Aliases & Classifications for Bronchial Adenomas/carcinoids Childhood

MalaCards integrated aliases for Bronchial Adenomas/carcinoids Childhood:

Name: Bronchial Adenomas/carcinoids Childhood 52
Bronchial Carcinoid Tumor 71
Bronchial Carcinoids 52

Classifications:



External Ids:

UMLS 71 C0238035

Summaries for Bronchial Adenomas/carcinoids Childhood

MalaCards based summary : Bronchial Adenomas/carcinoids Childhood, also known as bronchial carcinoid tumor, is related to adenoma and acromegaly. An important gene associated with Bronchial Adenomas/carcinoids Childhood is POMC (Proopiomelanocortin), and among its related pathways/superpathways are Relaxin signaling pathway and cAMP signaling pathway. The drugs Tranexamic Acid and Hemostatics have been mentioned in the context of this disorder. Affiliated tissues include lung, pituitary and thyroid.

Related Diseases for Bronchial Adenomas/carcinoids Childhood

Diseases related to Bronchial Adenomas/carcinoids Childhood via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 167)
# Related Disease Score Top Affiliating Genes
1 adenoma 30.5 SST POMC
2 acromegaly 30.4 SST POMC
3 pituitary adenoma 30.2 SST POMC
4 neuroendocrine tumor 30.2 SST POMC
5 conn's syndrome 30.1 SST POMC
6 multiple endocrine neoplasia, type i 29.7 SST POMC
7 diarrhea 29.7 SST POMC
8 small cell cancer of the lung 29.7 SST POMC
9 pituitary tumors 29.6 SST POMC
10 thyroid gland medullary carcinoma 29.6 SST POMC
11 pituitary-dependent cushing's disease 29.4 SST POMC
12 acth-secreting pituitary adenoma 29.4 SST POMC
13 ileus 29.4 SST POMC
14 pituitary gland disease 29.4 SST POMC
15 hypoglycemia 29.1 SST POMC
16 meningioma, familial 29.1 SST POMC
17 pheochromocytoma 29.0 SST POMC
18 carcinoid syndrome 10.6
19 carcinoid tumors, intestinal 10.5
20 lung benign neoplasm 10.2
21 small cell carcinoma 10.2
22 neuroendocrine carcinoma 10.2
23 pneumothorax 10.2
24 hypokalemia 10.2
25 multiple endocrine neoplasia 10.2
26 asthma 10.1
27 47,xyy 10.1
28 paraganglioma 10.1
29 pulmonary tuberculosis 10.1
30 adenocarcinoma 10.1
31 lung oat cell carcinoma 10.1
32 hypopituitarism 10.1
33 bronchiectasis 10.1
34 48,xyyy 10.1
35 paraneoplastic syndromes 10.1
36 thyroid carcinoma 10.1
37 thyroid carcinoma, familial medullary 10.0
38 osteoporosis 10.0
39 sarcoidosis 1 10.0
40 tetralogy of fallot 10.0
41 thyroid cancer, nonmedullary, 1 10.0
42 congenital heart defects, hamartomas of tongue, and polysyndactyly 10.0
43 oncocytoma 10.0
44 pulmonary disease, chronic obstructive 10.0
45 bone mineral density quantitative trait locus 8 10.0
46 lung cancer susceptibility 3 10.0
47 bone mineral density quantitative trait locus 15 10.0
48 large cell neuroendocrine carcinoma 10.0
49 adrenal gland pheochromocytoma 10.0
50 hyperparathyroidism 10.0

Graphical network of the top 20 diseases related to Bronchial Adenomas/carcinoids Childhood:



Diseases related to Bronchial Adenomas/carcinoids Childhood

Symptoms & Phenotypes for Bronchial Adenomas/carcinoids Childhood

Drugs & Therapeutics for Bronchial Adenomas/carcinoids Childhood

Drugs for Bronchial Adenomas/carcinoids Childhood (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Tranexamic Acid Approved Phase 3 1197-18-8 5526
2 Hemostatics Phase 3
3 Antifibrinolytic Agents Phase 3
4 Coagulants Phase 3

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 The Role of Inhalations of Tranexamic Acid in Patients With Hemoptysis Unknown status NCT01496196 Phase 3 tranexamic acid;tranexamic acid

Search NIH Clinical Center for Bronchial Adenomas/carcinoids Childhood

Genetic Tests for Bronchial Adenomas/carcinoids Childhood

Anatomical Context for Bronchial Adenomas/carcinoids Childhood

MalaCards organs/tissues related to Bronchial Adenomas/carcinoids Childhood:

40
Lung, Pituitary, Thyroid, Bone, Adrenal Gland, Lymph Node, Thymus

Publications for Bronchial Adenomas/carcinoids Childhood

Articles related to Bronchial Adenomas/carcinoids Childhood:

(show top 50) (show all 310)
# Title Authors PMID Year
1
Ectopic Cushing's syndrome associated with a pheochromocytoma in a dog: a case report. 61
32014021 2020
2
Bronchial Carcinoid tumour as a rare cause of Cushing’s syndrome in children – A case report and review of literature 61
31898446 2020
3
Human bronchial carcinoid tumor initiating cells are targeted by the combination of acetazolamide and sulforaphane. 61
31470802 2019
4
Postpneumonectomy-like syndrome due to bronchial carcinoid: a unique case report. 61
30777035 2019
5
Management of Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia: Review and a Single Center Experience. 61
30167840 2018
6
A quantitative method for assessing smoke associated molecular damage in lung cancers. 61
30225209 2018
7
Paraneoplastic Cushing syndrome, case-series and review of the literature. 61
28895465 2018
8
Bronchial carcinoid in anomalous right upper bronchus: a "patient-tailored" bronchoplasty resection technique. 61
29780727 2018
9
External Validation of a Prognostic Model of Survival for Resected Typical Bronchial Carcinoids. 61
28821334 2017
10
Typical carcinoid involving the main carina managed with arterial embolisation, endobronchial resection and ablation, ultimately followed by carinal resection. 61
28963389 2017
11
Source of Ectopic ACTH Secretion Easily Identified by 68 Ga DOTANOC PET/CT. 61
28098665 2017
12
Prognostic factors in ectopic Cushing's syndrome due to neuroendocrine tumors: a multicenter study. 61
28183788 2017
13
Dual Tracer PET Imaging (68Ga-DOTATATE and 18F-FDG) Features in Pulmonary Carcinoid: Correlation with Tumor Proliferation Index. 61
28242984 2017
14
Prognostic Factors in Typical and Atypical Pulmonary Carcinoids. 61
29230118 2017
15
Clinicopathological characteristics and prognosis of resected cases of carcinoid tumors of the lung. 61
27755793 2016
16
Management of bronchial carcinoids: international practice survey among the European Society of Thoracic Surgeons. 61
27301649 2016
17
Peptide receptor radionuclide therapy with (177)Lu-DOTATATE in advanced bronchial carcinoids: prognostic role of thyroid transcription factor 1 and (18)F-FDG PET. 61
26611427 2016
18
Predictors of Disease-free Survival and Recurrence in Patients with Resected Bronchial Carcinoid Tumors. 61
25756243 2016
19
[Metastatic bronchial carcinoid tumors]. 61
26831129 2016
20
Cushing's like syndrome in typical bronchial carcinoid a case report and review of the literature. 61
26923475 2016
21
cAMP effects in neuroendocrine tumors: The role of Epac and PKA in cell proliferation and adhesion. 61
26589262 2015
22
Intramedullary spinal metastasis of a carcinoid tumor. 61
26260116 2015
23
PET imaging in ectopic Cushing syndrome: a systematic review. 61
26206753 2015
24
Long-term follow-up after first-line bronchoscopic therapy in patients with bronchial carcinoids. 61
25777586 2015
25
Multidisciplinary management of advanced lung neuroendocrine tumors. 61
25984363 2015
26
PET/CT assessment of neuroendocrine tumors of the lung with special emphasis on bronchial carcinoids. 61
24850179 2014
27
Divergent management strategies for typical versus atypical carcinoid tumors of the thoracic cavity. 61
23357970 2014
28
Long-term results after resection of bronchial carcinoid tumour: evaluation of survival and prognostic factors. 61
24737788 2014
29
Operated bronchial carcinoids: clinical outcomes and long-term follow-up of a single institution series of 30 patients. 61
25195306 2014
30
The significance of histology: typical and atypical bronchial carcinoids. 61
25065930 2014
31
Bronchial carcinoids with oncocytic features and expressing GLUT1 receptor: does the intense (18)F-FDG uptake correlate with long-term survival? 61
25097900 2014
32
Management of endocrine disease: a clinical update on tumor-induced hypoglycemia. 61
24459236 2014
33
Which is the best strategy for diagnosing bronchial carcinoid tumours? The role of dual tracer PET/CT scan. 61
24563874 2014
34
Integrated FDG-PET/CT imaging is useful in the approach to carcinoid tumors of the lung. 61
24305515 2013
35
Ectopic ACTH-secreting syndrome: a single-center experience. 61
24013993 2013
36
Outcome and prognostic factors in bronchial carcinoids: a single-center experience. 61
24457239 2013
37
mTOR, p70S6K, AKT, and ERK1/2 levels predict sensitivity to mTOR and PI3K/mTOR inhibitors in human bronchial carcinoids. 61
23653462 2013
38
Combination of carbonic anhydrase inhibitor, acetazolamide, and sulforaphane, reduces the viability and growth of bronchial carcinoid cell lines. 61
23927827 2013
39
Disseminated typical bronchial carcinoid tumor. 61
23789293 2013
40
Two different types of carcinoid tumors of the lung: immunohistochemical and ultrastructural investigation and their histogenetic consideration. 61
23383615 2013
41
Effect of temozolomide in patients with metastatic bronchial carcinoids. 61
23969949 2013
42
Molecular and cellular biology of neuroendocrine lung tumors: evidence for separate biological entities. 61
22579738 2012
43
Long-term outcomes of surgical treatment for pulmonary carcinoid tumors: 20 years' experience with 131 patients. 61
22932173 2012
44
Can bronchial carcinoids be managed primarily with a bronchoscope? 61
23207348 2012
45
Surgical treatment for tracheobronchial carcinoid tumors: a 16-year experience. 61
22371943 2012
46
Mifepristone effects on tumor somatostatin receptor expression in two patients with Cushing's syndrome due to ectopic adrenocorticotropin secretion. 61
22090282 2012
47
Primary bronchial carcinoid: A rare differential diagnosis of pulmonary koch in young adult patient. 61
22345917 2012
48
Synergistic effects of erlotinib and everolimus on bronchial carcinoids and large-cell neuroendocrine carcinomas with activated EGFR/AKT/mTOR pathway. 61
22378048 2012
49
Endoscopic treatment of bronchial carcinoids in comparison to surgical resection: a retrospective study. 61
23207260 2012
50
Typical bronchial carcinoid metastasizing to the brain: a case presentation. 61
22291640 2011

Variations for Bronchial Adenomas/carcinoids Childhood

Expression for Bronchial Adenomas/carcinoids Childhood

Search GEO for disease gene expression data for Bronchial Adenomas/carcinoids Childhood.

Pathways for Bronchial Adenomas/carcinoids Childhood

Pathways related to Bronchial Adenomas/carcinoids Childhood according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.55 SST POMC
2 10.96 SST POMC

GO Terms for Bronchial Adenomas/carcinoids Childhood

Biological processes related to Bronchial Adenomas/carcinoids Childhood according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell-cell signaling GO:0007267 8.62 SST POMC

Molecular functions related to Bronchial Adenomas/carcinoids Childhood according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 8.62 SST POMC

Sources for Bronchial Adenomas/carcinoids Childhood

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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