Aliases & Classifications for Bronchial Disease

MalaCards integrated aliases for Bronchial Disease:

Name: Bronchial Disease 12 15 17
Bronchial Diseases 54 43 71
Bronchospasm 12 15
Bronchial Disorders 42
Bronchial Spasm 71

Classifications:



External Ids:

Disease Ontology 12 DOID:1176
MeSH 43 D001982
SNOMED-CT 67 41427001
UMLS 71 C0006261 C0006266

Summaries for Bronchial Disease

MedlinePlus : 42 When you breathe in, the air travels down through your trachea (windpipe). It then goes through two tubes to your lungs. These tubes are your bronchi. Bronchial disorders can make it hard for you to breathe. The most common problem with the bronchi is bronchitis, an inflammation of the tubes. It can be acute or chronic. Other problems include Bronchiectasis - a condition in which damage to the airways causes them to widen and become flabby and scarred Exercise-induced bronchospasm - a breathing problem that happens when your airways shrink while you are exercising Bronchiolitis - an inflammation of the small airways that branch off from the bronchi Bronchopulmonary dysplasia - a chronic lung condition in infants, most often premature infants

MalaCards based summary : Bronchial Disease, also known as bronchial diseases, is related to bronchiectasis and bronchitis, and has symptoms including dyspnea, apnea and wheezing. An important gene associated with Bronchial Disease is CCR6 (C-C Motif Chemokine Receptor 6), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Tramadol and Methadone have been mentioned in the context of this disorder. Affiliated tissues include lung, heart and trachea, and related phenotypes are hematopoietic system and digestive/alimentary

Disease Ontology : 12 A lower respiratory tract disease that affects the airways leading into the lungs, which is caused due to inflammation of the bronchi and bronchioles, infection, or blockage.

Wikipedia : 74 A bronchus is a passage or airway in the respiratory system that conducts air into the lungs. The first... more...

Related Diseases for Bronchial Disease

Diseases related to Bronchial Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 781)
# Related Disease Score Top Affiliating Genes
1 bronchiectasis 33.4 TNF SERPINA3 IL6 ELANE CXCL8
2 bronchitis 33.2 TNF RNASE3 IL6 IL5 IL4 IL13
3 asthma 32.9 TSLP TNF SERPINA3 RNASE3 MIR155 MIR126
4 ige responsiveness, atopic 31.9 RNASE3 IL5 IL4 IL13 IL10
5 allergic asthma 31.6 TSLP RNASE3 IL5 IL4 IL13 IL10
6 urticaria 31.6 TNF RNASE3 IL6 IL5 IL4 IL13
7 status asthmaticus 31.5 RNASE3 IL5 IL10 ELANE CXCL8 CCL11
8 allergic hypersensitivity disease 31.4 TSLP TNF RNASE3 IL5 IL4 IL13
9 pulmonary edema 31.4 TNF IL13 IL10 CXCL8
10 chronic rhinitis 31.2 RNASE3 IL5 IL4 IL13
11 exanthem 31.2 TNF IL6 IL10 ICOSLG H2AC18 CXCL8
12 pulmonary tuberculosis 31.2 TNF IL6 IL4 IL10 IFNGR1
13 silicosis 31.2 TNF IL4 IL10 CXCL8
14 sarcoidosis 1 31.2 TNF SERPINA3 MIR155 IL13 ICOSLG CD4
15 ileus 31.0 TNF IL6 IL10
16 penicillin allergy 31.0 IL4 IL13 IL10 IFNGR1
17 metal allergy 31.0 IL4 IL10 CD4
18 peanut allergy 31.0 IL5 IL4 IL13 IL10 ICOSLG CCR6
19 pulpitis 31.0 TNF IL6 CXCL8 CCR6
20 idiopathic interstitial pneumonia 31.0 MIR21 IL4 IL13 ELANE CXCL8 CCR6
21 cryptogenic organizing pneumonia 31.0 TNF CXCL8 CD4
22 ascaris lumbricoides infection 31.0 TSLP SERPINA3 IL6 IL5 IL13 CXCL8
23 pollen allergy 31.0 RNASE3 IL5 IL13
24 pleural disease 30.9 TNF IL6 H2AC18 CXCL8 CD4 CCR6
25 peritonitis 30.9 TNF IL6 IL4 IL10 ELANE CXCL8
26 sleep apnea 30.9 TNF IL6 IL10 CXCL8
27 churg-strauss syndrome 30.9 TNF RNASE3 IL5 IL10 CXCL8 CCL11
28 cerebral palsy 30.9 TNF IL6 IL10 CXCL8
29 vascular disease 30.9 TNF MIR21 MIR126 IL6 IL10 CD4
30 cellulitis 30.9 TNF RNASE3 IL6 IL5 IL10 ICOSLG
31 gastric ulcer 30.9 TNF IL6 CXCL8
32 crohn's disease 30.8 TNF IL6 IL4 IL10 ICOSLG CXCL8
33 lung cancer susceptibility 3 30.8 SERPINA3 MIR21 MIR126 IL6 ICOSLG H2AC18
34 human immunodeficiency virus type 1 30.8 TNF IL6 IL10 CD4 CCL11
35 cystic fibrosis 30.8 TNF RNASE3 IL6 IL10 ELANE CXCL8
36 mycobacterium tuberculosis 1 30.8 TNF SERPINA3 MIR21 MIR155 IL4 IL10
37 bacterial pneumonia 30.8 TNF MIR155 IL6 IL10 ICOSLG H2AC18
38 osteoporosis 30.7 TNF MIR21 IL6 IL4 IL10 CXCL8
39 lung disease 30.6 TNF SERPINA3 RNASE3 IL6 IL5 IL4
40 pertussis 30.6 TNF IL6 IL10 CXCL8 CCL11
41 intrinsic asthma 30.6 RNASE3 IL5 IL4 IL13 ICOSLG CD4
42 bronchiolitis obliterans 30.6 TNF IL6 IL13 IL10 CXCL8
43 body mass index quantitative trait locus 11 30.6 TNF SERPINA3 MIR21 MIR155 MIR126 IL6
44 interstitial lung disease 30.6 TNF IL6 IL5 IL4 IL13 IL10
45 bronchopneumonia 30.6 TNF SERPINA3 IL6 IL10 ELANE CXCL8
46 gastroesophageal reflux 30.6 TNF IL6 IL5 IL4 ELANE CXCL8
47 hypereosinophilic syndrome 30.5 RNASE3 IL5 IL4 IL13 IL10 CXCL8
48 ulcerative colitis 30.5 TNF IL6 IL4 IL13 IL10 CXCL8
49 allergic rhinitis 30.5 RNASE3 IL5 IL4 IL13 IL10 CXCL8
50 pulmonary emphysema 30.5 SERPINA3 ELANE CXCL8

Graphical network of the top 20 diseases related to Bronchial Disease:



Diseases related to Bronchial Disease

Symptoms & Phenotypes for Bronchial Disease

UMLS symptoms related to Bronchial Disease:


dyspnea, apnea, wheezing, snoring, coughing, expiratory wheeze, inspiratory wheeze

MGI Mouse Phenotypes related to Bronchial Disease:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.93 CCL11 CCR6 CD4 ELANE IFNGR1 IL10
2 digestive/alimentary MP:0005381 9.91 CD4 IFNGR1 IL10 IL13 IL4 IL5
3 immune system MP:0005387 9.73 CCL11 CCR6 CD4 ELANE IFNGR1 IL10
4 respiratory system MP:0005388 9.23 CCL11 IL10 IL13 IL4 IL5 IL6

Drugs & Therapeutics for Bronchial Disease

Drugs for Bronchial Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 275)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Tramadol Approved, Investigational Phase 4 27203-92-5 33741
2
Methadone Approved Phase 4 76-99-3 4095
3
Guaifenesin Approved, Investigational, Vet_approved Phase 4 93-14-1 3516
4
Fluticasone Approved, Experimental Phase 4 90566-53-3 62924
5
Epinephrine Approved, Vet_approved Phase 4 51-43-4 5816
6
Racepinephrine Approved Phase 4 329-65-7 838
7
Propofol Approved, Investigational, Vet_approved Phase 4 2078-54-8 4943
8
Omalizumab Approved, Investigational Phase 4 242138-07-4
9
Budesonide Approved Phase 4 51333-22-3 63006 5281004
10
Atropine Approved, Vet_approved Phase 4 5908-99-6, 51-55-8 174174
11
Ethanol Approved Phase 4 64-17-5 702
12
Esomeprazole Approved, Investigational Phase 4 161796-78-7, 161973-10-0, 119141-88-7 9568614 4594
13
Norepinephrine Approved Phase 4 51-41-2 439260
14
Terbutaline Approved Phase 4 23031-25-6 5403
15
Aspirin Approved, Vet_approved Phase 4 50-78-2 2244
16
Bisoprolol Approved Phase 4 66722-44-9 2405
17
Methylprednisolone Approved, Vet_approved Phase 4 83-43-2 6741
18
Methylprednisolone hemisuccinate Approved Phase 4 2921-57-5
19
Prednisolone Approved, Vet_approved Phase 4 50-24-8 5755
20
Prednisolone phosphate Approved, Vet_approved Phase 4 302-25-0
21 Prednisolone acetate Approved, Vet_approved Phase 4 52-21-1
22
Remifentanil Approved Phase 4 132875-61-7 60815
23
Dexmedetomidine Approved, Vet_approved Phase 4 113775-47-6 68602 5311068
24
Rocuronium Approved Phase 4 119302-91-9, 143558-00-3 441290
25
Succinylcholine Approved Phase 4 306-40-1 5314
26
Dopamine Approved Phase 4 51-61-6, 62-31-7 681
27
Loxapine Approved Phase 4 1977-10-2 3964
28
Sotalol Approved Phase 4 959-24-0, 3930-20-9 5253
29
Neostigmine Approved, Vet_approved Phase 4 59-99-4 4456
30
Acetaminophen Approved Phase 4 103-90-2 1983
31
Ketoprofen Approved, Vet_approved Phase 4 22071-15-4 3825
32
Cysteine Approved, Nutraceutical Phase 4 52-90-4 5862
33
Prednisolone hemisuccinate Experimental Phase 4 2920-86-7
34 Antitussive Agents Phase 4
35 Chlorpheniramine, phenylpropanolamine drug combination Phase 4
36 Protective Agents Phase 4
37 Bromides Phase 4
38 Sympathomimetics Phase 4
39
Salmeterol xinafoate Phase 4 94749-08-3 56801
40 Hormone Antagonists Phase 4
41 Fluticasone-Salmeterol Drug Combination Phase 4
42 Anti-Inflammatory Agents Phase 4
43 Anti-Allergic Agents Phase 4
44 glucocorticoids Phase 4
45 Epinephryl borate Phase 4
46 Mydriatics Phase 4
47 Hypnotics and Sedatives Phase 4
48
Beclomethasone Phase 4 4419-39-0 20469
49 Tiotropium Bromide Phase 4 136310-93-5
50 Parasympatholytics Phase 4

Interventional clinical trials:

(show top 50) (show all 258)
# Name Status NCT ID Phase Drugs
1 Effect of Single Dose of Tramadol on Extubation Response and Quality of Emergence(Cough and Nausea Vomiting) Following Supratentorial Intracranial Surgery Unknown status NCT02964416 Phase 4 Injection Tramadol
2 Evaluation Whether Higher Retention Rate is in Those of Combined Methadone With N-Acetyl-Cysteine Compared to Those With Methadone Alone During a Six-month Study Unknown status NCT01047956 Phase 4 Methadone; NAC;Methadone
3 Comparison of the Ahmed Glaucoma Valve FP7 and FP8 in Pediatric Glaucoma: a Randomized Clinical Trial. Unknown status NCT01494974 Phase 4
4 Street Fitness in Surgical Patients Undergoing General Anesthesia After Reversal of Neuromuscular Rest Blockade With Sugammadex Unknown status NCT01453530 Phase 4 Sugammadex;Neostigmine/Glycopyrrolate
5 Combivent vs. Salbutamol in Patients With Metacholine Induced Bronchospasm Completed NCT02182713 Phase 4 Salbutamol sulfate/Ipratropium bromide;Salbutamol
6 A Stratified, Multicenter, Randomized, Double-Blind, Parallel Group, 4-Week Comparison of Fluticasone Propionate/Salmeterol DISKUS Combination Product 100/50mcg BID Versus Fluticasone Propionate DISKUS 100mcg BID in Pediatric and Adolescent Subjects With Activity-Induced Bronchospasm Completed NCT00118716 Phase 4 Fluticasone propionate/salmeterol;Fluticasone Propionate
7 A Stratified, Multicenter, Randomized, Double-Blind, Parallel Group, 4-Week Comparison of Fluticasone Propionate/Salmeterol DISKUS Combination Product 100/50mcg BID Versus Fluticasone Propionate DISKUS 100mcg BID in Pediatric and Adolescent Subjects With Activity-Induced Bronchospasm Completed NCT00118690 Phase 4 Fluticasone propionate/salmeterol
8 Effectiveness of Ipratropium Bromide in Preventing Exercise-induced Bronchoconstriction in Athletes Completed NCT01691079 Phase 4 ipratropium bromide;Placebo
9 "Pretreatment With Albuterol vs. Montelukast in Exercise Induced Bronchospasm in Children." Completed NCT00273689 Phase 4 montelukast vs pretreatment with albuterol;montelukast
10 Efficacy Of Nebulised Beclometasone Versus Placebo In Preventing Viral Wheezing In Pre-School Children Completed NCT01265342 Phase 4 Beclomethasone;Placebo
11 An 8 Week Randomized, Placebo Controlled, Double-blind Study to Assess the Efficacy of Tiotropium Inhalation Capsules in Patients of African Descent With Chronic Obstructive Pulmonary Disease Completed NCT00106821 Phase 4 Tiotropium Bromide Inhalation Powder
12 Acute Effect of Salbutamol on Heart Rate and Blood Pressure During Exercise in Patients With Moderate or Severe Asthma and Healthy Subjects: Randomized, Double-blind, and Crossover Study Completed NCT03044938 Phase 4 salbutamol;Placebo
13 Impact of Continuous Positive Airway Pressure on the Treatment of Acute Asthma Exacerbation Completed NCT01403467 Phase 4
14 A Pilot Study to Evaluate the Effect of Nebulized Budesonide and Oral Corticosteroids on Wheezing Episode Relapse in Pediatric Patients Following Discharge From the Emergency Department/Outpatient Care Facility Completed NCT00189436 Phase 4 Nebulized Budesonide;Usual care (albuterol with or without oral steroid)
15 Effects of Esomeprazole on Gastric Emptying of Alcoholic Beverages, Blood Alcohol Concentrations, Gastroesophageal Reflux and Release of Some Gastrointestinal Hormones in Healthy Volunteers Completed NCT00472550 Phase 4 esomeprazole 20 mg
16 Preventive Effects of Penehyclidine Hydrochloride Inhalation on Postoperative Pulmonary Complications in High-risk Patients: a Randomized, Double-blind, and Placebo Controlled Study Completed NCT02644876 Phase 4 Penehyclidine inhalation;Placebo inhalation
17 Sugammadex Compared With Neostigmin/Atropin for Neuromuscular Block Reversal in Patients With Obstructive Sleep Apnea Completed NCT02160223 Phase 4 Sugammadex;Neostigmine
18 A Randomized, Open-label, Multicenter Study to Evaluate the Effect of Xolair (Omalizumab) as Add-on Therapy to Inhaled Corticosteroid + Long-Acting Beta Agonist in Fixed or Flexible Dosing Compared to Isolated Inhaled Corticosteroid + Long-Acting Beta Agonist in Fixed or Flexible Dosing in the Asthma-Related Quality of Life in Patients With Severe Persistent Allergic Asthma Completed NCT00567476 Phase 4 Omalizumab;Inhaled corticosteroids (ICS);Long-acting beta 2-adrenergic agonist (LABA);Short-acting beta 2-adrenergic agonist (SABA)
19 Videolaryngoscopes for Rapid Sequence Intubation Completed NCT02588157 Phase 4
20 A New Approach of Neostigmine in Unavoidable Post Operative Ileus After Surgery Completed NCT00676377 Phase 4 Neostigmine;Saline
21 The Effects on Airway Reactivity of the Use of Preoperative Montelukast Sodium Completed NCT02494466 Phase 4 montelukast sodium
22 Ketamine Tolerance in Children After Repeated Administrations During Radiotherapy Sessions Completed NCT02512055 Phase 4 Ketamine
23 Open, Randomized, Two-Way Crossover, Pilot Study to Assess the Effect of Salbutamol in Comparison With Ipratropium Bromide on Central and Peripheral Airway Dimensions in COPD Patients Completed NCT00911651 Phase 4 Salbutamol;ipratropium bromide
24 A Placebo Controlled, Double-Blind Investigation of the Therapeutic Utility of Xolair (Omalizumab) for Attenuating Aspirin Induced Bronchospasm in Patients With Aspirin Exacerbated Respiratory Disease (AERD) Undergoing Aspirin Desentization Completed NCT00555971 Phase 4 Omalizumab;placebo
25 A Randomized, Double-Blind, Parallel Group, Multicenter Study of the Effects of Fluticasone Propionate/Salmeterol Combination Product 250/50mcg BID (ADVAIR DISKUS™) in Comparison to Salmeterol 50mcg BID (SEREVENT DISKUS™) on the Rate of Exacerbations of COPD Following Hospitalization Completed NCT01110200 Phase 4 ADVAIR DISKUS 250/50 mg BID;SEREVENT 50 mcg BID
26 Phase 4 Study of Optimal Relaxation With Rocuronium Infusion Followed by Rapid Reliable Reversal With Sugammadex: A Comparison With Conventional Practice Completed NCT01539044 Phase 4 Neostigmine, atropine;Sugammadex
27 Impact of the Administration of Systemic Glucocorticoids on Inflammatory Response and Clinical Evolution of Patients Diagnosed With Moderate- Severe Bronchiolitis Completed NCT02571517 Phase 4 Glucocorticoids
28 Effect of Deep Curarisation and Reversal With Sugammadex on Surgical Conditions and Perioperative Morbidity in Patients Undergoing Laparoscopic Gastric Bypass Surgery Completed NCT01748643 Phase 4 deep neuromuscular blockade with rocuronium, reversal with sugammadex;normal neuromuscular blockade reversal with rocuronium, reversal with neostigmine
29 Proof of Concept Study to Assess the Differential Effects of Chronic Beta-blockade (Celiprolol Versus Bisoprolol) on Cardiopulmonary Outcomes at Rest and During Exercise in Chronic Obstructive Pulmonary Disease Completed NCT02380053 Phase 4 Bisoprolol;Celiprolol
30 Pilot Study: Epinephrine, Dexamethasone, and Hypertonic Saline in Children With Bronchiolitis, Randomised Clinical Trial of Efficacy and Safety Completed NCT01834820 Phase 4 Epinephrine and Dexamethasone;Hypertonic Saline;Normal Saline
31 THE EFFECT OF DIFFERENT INDUCTION TECHNIQUES ON POSTOPERATIVE PAIN AND AGITATION IN CHILDREN Completed NCT02110745 Phase 4 Sevofluorane;Propofol
32 Nasal Budesonide in Children With Rhinitis and/or Mild Obstructive Sleep Apnea Syndrome Completed NCT00560586 Phase 4 Budesonide;placebo
33 Eliminating Use of Non Depolarizing Neuromuscular Blocking Agents to Reduce Postoperative Pulmonary Complications: A Multi-center, Randomized Control Trial Recruiting NCT03962725 Phase 4 Neuromuscular Blocking Agents;Anesthetic Adjuncts
34 Asthma and Childhood Obesity: Understanding Potential Mechanisms and Identifying Strategies to Improve Respiratory Symptoms Recruiting NCT03586544 Phase 4 Albuterol
35 A Phase IV, Open-label, Non-randomized, Clinical Trial to Evaluate the Safety of Self-administered ADASUVE® (Staccato Loxapine for Inhalation) in Agitated Patients Outside the Hospital Setting Recruiting NCT02525991 Phase 4
36 A Pilot and Feasibility Study to Determine if a Common Atrial Fibrillation Risk Locus Modulates Differential Response to Antiarrhythmic Drugs Recruiting NCT02347111 Phase 4 Flecainide;Sotalol
37 Impact of Prophylactic Penehyclidine Hydrochloride Inhalation on Long-term Outcome in High-risk Patients: 3-year Follow-up of a Randomized Controlled Trial Active, not recruiting NCT03868709 Phase 4 Penehyclidine inhalation;Placebo inhalation
38 The Effect of Sugammadex Versus Neostigmine on Postoperative Pulmonary Complications in Patients 70 Years or Older and Scheduled for 3 Hour or Longer Surgery-A Randomized Controlled Trial Active, not recruiting NCT02861131 Phase 4 Sugammadex;Neostigmine
39 Comparing the Efficacy of Intravenous Paracetamol and Ketoprofen When Treating Renal Colic in Emergency Situations: a Randomized, Bi-centric, Double-blind Controlled Trial Suspended NCT01685658 Phase 4 Intravenous ketoprofen;Intravenous paracetamol
40 A Pilot Study to Determine the Most Effective Dose of Arformoterol for Treating Acute Asthmatic Patients Presenting to the Emergency Department and to Evaluate Its Side Effect and Safety Profile When Used in This Clinical Situation. Terminated NCT00819637 Phase 4 arformoterol (RR formoterol);placebo;levalbuterol
41 MASTER-ED : Magnesium Sulfate to Prevent Hospitalisation of Acute Exacerbations of Chronic Obstructive Pulmonary Disease Seen in the Emergency Department Withdrawn NCT02498496 Phase 4 Magnesium Sulfate;Placebo
42 Topical Timolol for the Treatment of Benign Vascular Periocular Lesions Withdrawn NCT01250457 Phase 4 topical Timolol
43 Inhaled Nebulised S(+)-Ketamine for Postoperative Analgesia Withdrawn NCT02397356 Phase 4 Ketamine first AB;Placebo first BA
44 Ketamine Efficacy for Acute Severe Bronchospasm in Mechanically Ventilated-critically Ill Patients: a Randomized Controlled Trial Unknown status NCT03000413 Phase 2, Phase 3 Ketamine;Fentanyl
45 Isoflurane Versus Small Dose Propofol With Isoflurane for Removal of Laryngeal Mask Airway in Anesthetized Children Unknown status NCT01958138 Phase 2, Phase 3 comparison of group-P (low dose propofol with isoflurane) versus group-D (alone isoflurane)
46 Intravenous Versus Oral Regimens of Dexamethasone for Prophylaxis of Paclitaxel-associated Hypersensitivity Reaction in Primary Ovarian, Fallopian Tube and Peritoneal Cancer Patients: a Double-blind Randomized Controlled Trial Unknown status NCT02349763 Phase 3 Intravenous Dexamethasone;Oral Dexamethasone
47 A Single-Dose Efficacy Comparison of Albuterol Hydrofluoroalkane (HFA) Breath-operated Inhaler (BOI) (Volare Easi-Breathe™) and Albuterol HFA Meter Dose Inhaler (MDI) (Volare™) in Adolescents and Adults With Exercise-Induced Bronchospasm Completed NCT00085774 Phase 3 albuterol aerosol by HFA MDI;albuterol aerosol by HFA BOI;placebo aerosol by HFA
48 A Double-Blind, Randomized, Placebo-Controlled, Multicenter, 2-Period, Crossover Study to Evaluate the Effects of a Single Dose of Montelukast on Exercise-Induced Bronchospasm Completed NCT00092131 Phase 3 Comparator: Montelukast;Comparator: Placebo
49 A Double-Blind, Randomized, Placebo-Controlled, Multicenter, 2-Period, Crossover Study to Evaluate the Effects of a Single Dose of Montelukast on Exercise-Induced Bronchospasm Completed NCT00090142 Phase 3 Comparator: Montelukast;Comparator: Placebo
50 An Efficacy Study of Single-Dose Levalbuterol Tartrate HFA MDI Versus Placebo in Prevention of EIB in Subjects 18 Years of Age and Older With EIB Completed NCT00268723 Phase 3 Levalbuterol tartrate HFA MDI;Placebo

Search NIH Clinical Center for Bronchial Disease

Inferred drug relations via UMLS 71 / NDF-RT 50 :


Aminophylline
aminophylline dihydrate
AMINOPHYLLINE PWDR
bitolterol
bitolterol mesylate
Cromolyn
Cromolyn Sodium
Ephedra vulgaris preparation
Ephedrine
Ephedrine hydrochloride
Ephedrine sulfate
EPHEDRINE TANNATE
Epinephrine
epinephrine bitartrate
epinephrine hydrochloride
epinephryl borate
formoterol
formoterol fumarate
formoterol fumarate dihydrate
Ipratropium
Ipratropium Bromide
Isoetharine
Isoetharine hydrochloride
Isoetharine Mesylate
Levalbuterol
metaproterenol
Metaproterenol Sulfate
oxtriphylline
pirbuterol
Pirbuterol acetate
Racepinephrine Hydrochloride
salmeterol
Salmeterol xinafoate
Theophylline
Theophylline anhydrous
Theophylline calcium salicylate
Theophylline Sodium Glycinate
Triamcinolone
Triamcinolone Acetonide
TRIAMCINOLONE ACETONIDE PWDR
triamcinolone diacetate
triamcinolone hexacetonide

Cochrane evidence based reviews: bronchial diseases

Genetic Tests for Bronchial Disease

Anatomical Context for Bronchial Disease

MalaCards organs/tissues related to Bronchial Disease:

40
Lung, Heart, Trachea, Bone, Liver, Testes, Skin

Publications for Bronchial Disease

Articles related to Bronchial Disease:

(show top 50) (show all 414)
# Title Authors PMID Year
1
Clinical Heterogeneity in Bronchiectasis. Recommended Reading from the Singapore Respiratory Medicine Fellows. 42
31106570 2019
2
Acupoint herbal patching for bronchitis: A protocol systematic review of randomized controlled trials. 42
31335684 2019
3
Corporate Memory and Rediscovering the Wheel. 42
31109188 2019
4
Bronchial inflammation: its relationship to colonizing microbial load and alpha(1)-antitrypsin deficiency. 54 61
10843958 2000
5
The interrelationship of sputum inflammatory markers in patients with chronic bronchitis. 54 61
10471615 1999
6
Laryngeal, Tracheal, and Bronchial Disease in the Mucopolysaccharidoses: Endoscopic Study. 61
31936731 2020
7
Subtyping COPD by Using Visual and Quantitative CT Imaging Features. 61
31283919 2020
8
A comparison of diagnostic consistency for asthma-chronic obstructive pulmonary disease overlap and clinical characteristics study. 61
31852476 2019
9
Eosinophilic COPD Patients Display a Distinctive Serum miRNA Profile From Asthma and Non-eosinophilic COPD. 61
31732359 2019
10
Low recurrence of lung adenoid cystic carcinoma with radiotherapy and resection. 61
31067606 2019
11
[Azithromycine and chronic bronchial diseases: For which patients? For which benefits? With what modalities?] 61
30857823 2019
12
[Feline asthma and chronic bronchitis - an overview of diagnostics and therapy]. 61
31212350 2019
13
Evaluation of Bronchoscopy and Bronchoalveolar Lavage Findings in Cats With Aelurostrongylus abstrusus in Comparison to Cats With Feline Bronchial Disease. 61
31632989 2019
14
Male patient with chronic bronchial disease and bullous emphysema superinfection. 61
29703394 2018
15
Metallic small y stent placement at primary right carina for bronchial disease. 61
30497447 2018
16
[Bronchiectasis imaging]. 61
30348546 2018
17
Role of Endovascular Aortic Repair in the Treatment of Infected Aortic Aneurysms Complicated by Aortoenteric or Aortobronchial Fistulae. 61
29207434 2018
18
Detection of specific bacterial agents by quantitative PCR assays in the bronchoalveolar lavage fluid of dogs with eosinophilic bronchopneumopathy vs. dogs with chronic bronchitis and healthy dogs. 61
29428092 2018
19
Feline Troglostrongylosis: Current Epizootiology, Clinical Features, and Therapeutic Options. 61
29974053 2018
20
The computed tomographic "tree-in-bud" pattern: Characterization and comparison with radiographic and clinical findings in 36 cats. 61
28994206 2018
21
[Butamirate citrate in control of cough in respiratory tract inflammation]. 61
28875973 2017
22
Beyond bronchitis: a review of the congenital and acquired abnormalities of the bronchus. 61
27966195 2017
23
Nonallergic rhinitis and lower airway disease. 61
27439024 2017
24
Numerical study of the effects of bronchial structural abnormalities on respiratory flow distribution. 61
28155703 2016
25
Novel Mutation of Interferon-γ Receptor 1 Gene Presenting as Early Life Mycobacterial Bronchial Disease. 61
27868075 2016
26
Associations between respiratory signs and abnormalities reported in thoracic CT scans of cats. 61
27467170 2016
27
The tobacco paradox in acute coronary syndrome. The prior cessation of smoking as a marker of a better short-term prognosis. 61
27118137 2016
28
A case of IgG4-related bronchial disease successfully treated with inhaled corticosteroids. 61
26441152 2016
29
Respiratory syncytial virus infection and bronchial hyperreactivity in children up to two years of age in correlation with atopy. 61
26964386 2016
30
[Morphometric characteristics of the bronchial tree in smokers with and without chronic obstructive pulmonary disease]. 61
27030324 2016
31
Computed tomographic bronchioarterial ratio for brachycephalic dogs without pulmonary disease. 61
25643795 2015
32
Diffuse panbronchiolitis in an Australian aborigine. 61
25473569 2014
33
'Heavier the interval than the consummation': bronchial disease in Seán Ó Ríordáin's diaries. 61
24002457 2014
34
Progression and prognostic indicators of bronchial disease in children with sickle cell disease. 61
24699774 2014
35
[Long-term macrolide treatment in adult chronic bronchial diseases: benefits and limits]. 61
24631048 2014
36
Bronchial stent placement in a dog with bronchomalacia and left atrial enlargement. 61
24506740 2014
37
Bronchoalveolar lavage fluid and serum canine surfactant protein A concentrations in dogs with chronic cough by bronchial and interstitial lung diseases. 61
24366151 2014
38
Tissue remodelling in chronic bronchial diseases: from the epithelial to mesenchymal phenotype. 61
24591669 2014
39
[Chest computed tomography in children: indications, efficiency and effective dose]. 61
24485863 2014
40
Indoor air pollution: impact on health and stem cells. 61
25942342 2014
41
Lower respiratory tract endoscopy in the cat: diagnostic approach to bronchial disease. 61
24152702 2013
42
Inhaled budesonide therapy in cats with naturally occurring chronic bronchial disease (feline asthma and chronic bronchitis). 61
24000786 2013
43
Bronchiolitis obliterans syndrome after allogeneic hematopoietic SCT: phenotypes and prognosis. 61
23208317 2013
44
Correlation of bronchoalveolar eosinophilic percentage with airway responsiveness in cats with chronic bronchial disease. 61
23617298 2013
45
Influence of inspiration level on bronchial lumen measurements with computed tomography. 61
22154247 2012
46
Lung morphology assessment with balanced steady-state free precession MR imaging compared with CT. 61
22396606 2012
47
Pneumococcus infections: is the burden still as heavy? 61
22424795 2012
48
Lower respiratory tract infections in cats: reaching beyond empirical therapy. 61
21515220 2011
49
Limited stage I disease is not necessarily indicative of an excellent prognosis in childhood anaplastic large cell lymphoma. 61
21444917 2011
50
[Drug-induced lung diseases]. 61
21432739 2011

Variations for Bronchial Disease

Expression for Bronchial Disease

Search GEO for disease gene expression data for Bronchial Disease.

Pathways for Bronchial Disease

Pathways related to Bronchial Disease according to GeneCards Suite gene sharing:

(show top 50) (show all 54)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
14.02 TNF SERPINA3 RNASE3 IL6 IL5 IL4
2
Show member pathways
13.86 TNF IL6 IL5 IL4 IL13 IL10
3
Show member pathways
13.72 TSLP TNF IL6 IL5 IL4 IL13
4
Show member pathways
13.59 TNF IL6 IL5 IL4 IL13 IL10
5
Show member pathways
13.47 TNF IL6 IL5 IL4 IL13 IL10
6
Show member pathways
13.42 TNF IL6 IL5 IL4 IL13 IL10
7
Show member pathways
13.32 TNF IL6 IL5 IL4 IL13 IL10
8 12.89 IL6 IL5 IL4 IL13 IFNGR1 CXCL8
9
Show member pathways
12.71 TNF IL4 IL10 IFNGR1 ICOSLG CD4
10
Show member pathways
12.68 TNF IL6 IL5 IL4 IL10 IFNGR1
11
Show member pathways
12.64 TNF RNASE3 IL6 IL5 IL4 IL13
12
Show member pathways
12.63 TNF IL6 IL5 IL4 IL13 IL10
13
Show member pathways
12.43 TNF IL6 IL10 CXCL8 CCR6 CCL11
14
Show member pathways
12.39 TNF IL6 IL5 IL4 IL13 CXCL8
15
Show member pathways
12.39 TSLP IL6 IL5 IL4 IL13 IL10
16
Show member pathways
12.35 TNF SERPINA3 IL6 IL4
17
Show member pathways
12.34 RNASE3 ELANE CD4 CCR6
18
Show member pathways
12.34 TNF IL6 IL5 IL4 IL13 IL10
19
Show member pathways
12.28 TNF IL4 IL10 IFNGR1
20 12.26 TNF IL6 IL10 IFNGR1
21 12.25 TNF IL6 IL13 IL10 CXCL8
22
Show member pathways
12.23 TNF IL6 IL4 IFNGR1 CXCL8 CCL11
23
Show member pathways
12.14 TNF IL6 IL10 IFNGR1 CD4
24
Show member pathways
12.09 TNF IL6 IL4 IL13
25 12.07 TNF IL6 IL5 IL4 IL10 CD4
26 12.06 TNF IL6 IL10 CXCL8
27 12.06 TNF IL6 IL4 CXCL8
28 12.03 TNF IL6 IL4 IL13 IL10 CXCL8
29 12.02 TNF IL6 IL5 IL4 CD4
30 11.99 TNF IL6 IL10 CXCL8
31 11.89 IL6 IL5 IL4 IL13 CXCL8
32 11.85 TNF IL6 IL10 CXCL8
33
Show member pathways
11.84 TNF IL5 IL4 CXCL8
34 11.83 TNF IL6 IL10 CD4
35 11.79 IL6 IFNGR1 CXCL8
36 11.79 TNF IL6 IL4 IL13 IL10 CCL11
37 11.75 IL5 IL4 IL10 CCL11
38
Show member pathways
11.68 TNF IL6 CXCL8
39 11.64 TNF IL6 IL10 CXCL8
40 11.63 TNF IL6 CXCL8
41 11.61 TSLP IL6 CXCL8 CCL11
42 11.6 TNF IL6 IL5 IL4 IL13 CXCL8
43 11.57 TNF IL6 IL4 IL13 IL10 CXCL8
44 11.56 TNF IL6 ELANE
45 11.51 IL5 IL4 IL13 IL10 CD4 CCL11
46 11.46 TSLP TNF IL5 IL4 IL13 IL10
47 11.44 TNF IL6 IL10
48 11.41 TNF IL6 IL10
49 11.31 IL5 IL4 IL13 IL10
50 11.3 TSLP TNF IL6 IL5 IL4 IL13

GO Terms for Bronchial Disease

Cellular components related to Bronchial Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.73 TSLP TNF SERPINA3 RNASE3 IL6 IL5
2 external side of plasma membrane GO:0009897 9.55 TNF IL13 ICOSLG CD4 CCR6
3 extracellular space GO:0005615 9.5 TSLP TNF SERPINA3 RNASE3 MIR21 MIR155

Biological processes related to Bronchial Disease according to GeneCards Suite gene sharing:

(show all 48)
# Name GO ID Score Top Affiliating Genes
1 signal transduction GO:0007165 10.2 TSLP IL6 IL5 IL4 IL10 IFNGR1
2 positive regulation of transcription, DNA-templated GO:0045893 10.11 TNF IL6 IL5 IL4 IL10 CD4
3 positive regulation of gene expression GO:0010628 9.98 TNF MIR21 MIR155 IL6 IL4 IL13
4 defense response to bacterium GO:0042742 9.97 TNF RNASE3 MIR155 IL10 ELANE
5 response to lipopolysaccharide GO:0032496 9.96 MIR155 IL13 IL10 ELANE
6 positive regulation of angiogenesis GO:0045766 9.93 MIR21 MIR126 CXCL8 CCL11
7 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.93 TNF MIR21 MIR126 CD4 CCL11
8 negative regulation of inflammatory response GO:0050728 9.92 MIR155 MIR126 IL10 ELANE
9 positive regulation of DNA-binding transcription factor activity GO:0051091 9.89 TNF IL6 IL5 IL10
10 cellular response to lipopolysaccharide GO:0071222 9.89 TNF MIR21 IL6 IL10 CXCL8
11 chemokine-mediated signaling pathway GO:0070098 9.87 CXCL8 CCR6 CCL11
12 response to glucocorticoid GO:0051384 9.86 TNF IL6 IL10
13 positive regulation of T cell proliferation GO:0042102 9.85 IL6 IL4 CD4
14 positive regulation of interleukin-6 production GO:0032755 9.85 TSLP TNF IL6
15 humoral immune response GO:0006959 9.84 TNF IL6 CCR6
16 positive regulation of vascular smooth muscle cell proliferation GO:1904707 9.83 TNF MIR21 IL10
17 T cell activation GO:0042110 9.83 IL4 ICOSLG CD4
18 positive regulation of B cell proliferation GO:0030890 9.8 IL5 IL4 IL13
19 positive regulation of smooth muscle cell proliferation GO:0048661 9.78 TNF IL6 IL13 ELANE
20 microglial cell activation GO:0001774 9.76 TNF IL13 IFNGR1
21 inflammatory response GO:0006954 9.76 TNF SERPINA3 IL6 IL5 IL13 IL10
22 negative regulation of neurogenesis GO:0050768 9.75 TNF IL6 CCL11
23 positive regulation of sprouting angiogenesis GO:1903672 9.73 MIR155 MIR126 IL10
24 positive regulation of activated T cell proliferation GO:0042104 9.72 MIR21 MIR155 ICOSLG
25 positive regulation of inflammatory response GO:0050729 9.72 TSLP TNF MIR21 MIR155 MIR126
26 negative regulation of endothelial cell apoptotic process GO:2000352 9.71 MIR126 IL4 IL13 IL10
27 negative regulation of amyloid-beta clearance GO:1900222 9.7 TNF IFNGR1
28 positive regulation of MHC class II biosynthetic process GO:0045348 9.7 IL4 IL10
29 negative regulation of tumor necrosis factor biosynthetic process GO:0042536 9.7 IL4 IL10
30 positive regulation of chemokine production GO:0032722 9.7 TSLP TNF IL6
31 positive regulation of interleukin-13 production GO:0032736 9.69 TSLP IL4
32 negative regulation of interleukin-8 production GO:0032717 9.69 MIR155 IL10
33 negative regulation of lipid storage GO:0010888 9.69 TNF IL6
34 positive regulation of macrophage activation GO:0043032 9.69 MIR155 IL13 IL10
35 leukocyte migration involved in inflammatory response GO:0002523 9.68 ELANE CCR6
36 endothelial cell apoptotic process GO:0072577 9.68 TNF IL10
37 negative regulation of regulatory T cell differentiation GO:0045590 9.68 MIR21 MIR155
38 positive regulation of JAK-STAT cascade GO:0046427 9.67 TNF IL6 IL5 IL10
39 negative regulation of cytokine secretion involved in immune response GO:0002740 9.66 TNF IL10
40 negative regulation of bicellular tight junction assembly GO:1903347 9.65 TNF MIR155
41 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.65 TSLP TNF IL6 IL4 IL13
42 immune response GO:0006955 9.65 TNF IL6 IL5 IL4 IL13 IL10
43 type 2 immune response GO:0042092 9.64 IL4 IL10
44 regulation of isotype switching GO:0045191 9.63 IL4 IL10
45 negative regulation of complement-dependent cytotoxicity GO:1903660 9.61 IL4 IL13
46 negative regulation of chemokine biosynthetic process GO:0045079 9.61 IL6 ELANE
47 receptor biosynthetic process GO:0032800 9.6 TNF IL10
48 cytokine-mediated signaling pathway GO:0019221 9.32 TNF IL6 IL5 IL4 IL13 IL10

Molecular functions related to Bronchial Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.28 TSLP TNF IL6 IL5 IL4 IL13
2 growth factor activity GO:0008083 9.26 IL6 IL5 IL4 IL10

Sources for Bronchial Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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