MCID: BRN137
MIFTS: 31

Bronchial Neuroendocrine Tumor

Categories: Endocrine diseases, Neuronal diseases, Rare diseases, Respiratory diseases

Aliases & Classifications for Bronchial Neuroendocrine Tumor

Summaries for Bronchial Neuroendocrine Tumor

MalaCards based summary : Bronchial Neuroendocrine Tumor, also known as bronchial net, is related to neuroendocrine tumor and conn's syndrome. An important gene associated with Bronchial Neuroendocrine Tumor is AVPR1B (Arginine Vasopressin Receptor 1B). Affiliated tissues include lung, trachea and liver, and related phenotypes are hypotension and hepatomegaly

Related Diseases for Bronchial Neuroendocrine Tumor

Diseases related to Bronchial Neuroendocrine Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 neuroendocrine tumor 10.2
2 conn's syndrome 9.9

Symptoms & Phenotypes for Bronchial Neuroendocrine Tumor

Human phenotypes related to Bronchial Neuroendocrine Tumor:

59 32 (show all 31)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 hypotension 59 32 very rare (1%) Very rare (<4-1%) HP:0002615
2 hepatomegaly 59 32 very rare (1%) Very rare (<4-1%) HP:0002240
3 dyspnea 59 32 frequent (33%) Frequent (79-30%) HP:0002094
4 weight loss 59 32 frequent (33%) Frequent (79-30%) HP:0001824
5 anorexia 59 32 frequent (33%) Frequent (79-30%) HP:0002039
6 hemoptysis 59 32 frequent (33%) Frequent (79-30%) HP:0002105
7 asthma 59 32 frequent (33%) Frequent (79-30%) HP:0002099
8 chest pain 59 32 frequent (33%) Frequent (79-30%) HP:0100749
9 growth hormone excess 59 32 very rare (1%) Very rare (<4-1%) HP:0000845
10 hepatic failure 59 32 very rare (1%) Very rare (<4-1%) HP:0001399
11 pneumonia 59 32 frequent (33%) Frequent (79-30%) HP:0002090
12 increased circulating acth level 59 32 very rare (1%) Very rare (<4-1%) HP:0003154
13 tricuspid regurgitation 59 32 very rare (1%) Very rare (<4-1%) HP:0005180
14 interstitial pulmonary abnormality 59 32 frequent (33%) Frequent (79-30%) HP:0006530
15 increased circulating cortisol level 59 32 very rare (1%) Very rare (<4-1%) HP:0003118
16 night sweats 59 32 very rare (1%) Very rare (<4-1%) HP:0030166
17 poor appetite 59 32 frequent (33%) Frequent (79-30%) HP:0004396
18 palpitations 59 32 very rare (1%) Very rare (<4-1%) HP:0001962
19 pulmonary carcinoid tumor 59 32 obligate (100%) Obligate (100%) HP:0030445
20 cardiogenic shock 59 32 very rare (1%) Very rare (<4-1%) HP:0030149
21 right ventricular failure 59 32 very rare (1%) Very rare (<4-1%) HP:0001708
22 chronic noninfectious lymphadenopathy 59 32 frequent (33%) Frequent (79-30%) HP:0002730
23 wheezing 59 32 frequent (33%) Frequent (79-30%) HP:0030828
24 facial telangiectasia 59 32 very rare (1%) Very rare (<4-1%) HP:0007380
25 nonproductive cough 59 32 frequent (33%) Frequent (79-30%) HP:0031246
26 dermatological manifestations of systemic disorders 59 32 very rare (1%) Very rare (<4-1%) HP:0001005
27 increased serum serotonin 59 32 very rare (1%) Very rare (<4-1%) HP:0003144
28 protracted diarrhea 59 32 very rare (1%) Very rare (<4-1%) HP:0004385
29 bowel urgency 59 32 very rare (1%) Very rare (<4-1%) HP:0012701
30 bronchospasm 59 32 very rare (1%) Very rare (<4-1%) HP:0025428
31 abnormal pulmonary valve cusp morphology 59 32 very rare (1%) Very rare (<4-1%) HP:0031566

MGI Mouse Phenotypes related to Bronchial Neuroendocrine Tumor:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.13 AVPR1B GHRL RLN1
2 endocrine/exocrine gland MP:0005379 8.8 AVPR1B GHRL RLN1

Drugs & Therapeutics for Bronchial Neuroendocrine Tumor

Search Clinical Trials , NIH Clinical Center for Bronchial Neuroendocrine Tumor

Genetic Tests for Bronchial Neuroendocrine Tumor

Anatomical Context for Bronchial Neuroendocrine Tumor

MalaCards organs/tissues related to Bronchial Neuroendocrine Tumor:

41
Lung, Trachea, Liver, Pineal

Publications for Bronchial Neuroendocrine Tumor

Articles related to Bronchial Neuroendocrine Tumor:

# Title Authors Year
1
Management and Follow-up of Patients with a Bronchial Neuroendocrine Tumor in the Last Twenty Years in Ireland: Expected Inconsistencies and Unexpected Discoveries. ( 30228817 )
2018
2
Metastatic bronchial neuroendocrine tumor to the pineal gland: a unique manifestation of a rare disease. ( 20363727 )
2010
3
Carcinoid crisis induced by receptor radionuclide therapy with 90Y-DOTATOC in a case of liver metastases from bronchial neuroendocrine tumor (atypical carcinoid). ( 16840837 )
2006
4
Cyclical Cushing's syndrome in a patient with a bronchial neuroendocrine tumor (typical carcinoid) expressing ghrelin and growth hormone secretagogue receptors. ( 14671177 )
2003

Variations for Bronchial Neuroendocrine Tumor

Expression for Bronchial Neuroendocrine Tumor

Search GEO for disease gene expression data for Bronchial Neuroendocrine Tumor.

Pathways for Bronchial Neuroendocrine Tumor

GO Terms for Bronchial Neuroendocrine Tumor

Biological processes related to Bronchial Neuroendocrine Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of signaling receptor activity GO:0010469 8.96 GHRL RLN1
2 positive regulation of cytosolic calcium ion concentration GO:0007204 8.62 AVPR1B GHRL

Molecular functions related to Bronchial Neuroendocrine Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 8.62 GHRL RLN1

Sources for Bronchial Neuroendocrine Tumor

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....