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MCID: BRN024
MIFTS: 70

Bronchitis

Categories: Respiratory diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs
Sources

Aliases & Classifications for Bronchitis

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MalaCards integrated aliases for Bronchitis:

Name: Bronchitis 12 45 15 17 74 3 64
Chronic Bronchitis 12 77 30 44 15 17
Acute Bronchitis 12 44 74 64
Bronchitis, Chronic 77 45 74
Chest Cold 12 3
Acute Lower Respiratory Tract Infection 74
Acute Bronchitis and Bronchiolitis 12
Lower Respiratory Tract Infection 74
Recurrent Wheezy Bronchitis 12
Ci - Chest Infection 12
Bronchitis Chronic 56
Chest Infection 12

Classifications:

MalaCards categories:
Anatomical: Respiratory diseases
See all MalaCards categories (disease lists)
ICD10: 34


Sources

Summaries for Bronchitis

About this section
MedlinePlus : 44 Bronchitis is an inflammation of the bronchial tubes, the airways that carry air to your lungs. It causes a cough that often brings up mucus. It can also cause shortness of breath, wheezing, a low fever, and chest tightness. There are two main types of bronchitis: acute and chronic. Most cases of acute bronchitis get better within several days. But your cough can last for several weeks after the infection is gone. The same viruses that cause colds and the flu often cause acute bronchitis. These viruses spread through the air when people cough, or though physical contact (for example, on unwashed hands). Being exposed to tobacco smoke, air pollution, dusts, vapors, and fumes can also cause acute bronchitis. Less often, bacteria can also cause acute bronchitis. To diagnose acute bronchitis, your health care provider will ask about your symptoms and listen to your breathing. You may also have other tests. Treatments include rest, fluids, and aspirin (for adults) or acetaminophen to treat fever. A humidifier or steam can also help. You may need inhaled medicine to open your airways if you are wheezing. Antibiotics won't help if the cause is viral. You may get antibiotics if the cause is bacterial. NIH: National Heart, Lung, and Blood Institute

MalaCards based summary : Bronchitis, also known as chronic bronchitis, is related to sinusitis and hypereosinophilic syndrome, and has symptoms including cough, shortness of breath and chest tightness. An important gene associated with Bronchitis is ELANE (Elastase, Neutrophil Expressed), and among its related pathways/superpathways are Innate Immune System and Allograft rejection. The drugs Augmentin and Avelox I.V. have been mentioned in the context of this disorder. Affiliated tissues include lung, testes and heart, and related phenotypes are hematopoietic system and homeostasis/metabolism

Disease Ontology : 12 A bronchial disease that is an inflammation of the bronchial tubes. It is caused by bacteria and viruses. The disease has symptom cough with mucus, has symptom shortness of breath, has symptom low fever and has symptom chest tightness.

CDC : 3 Español: Bronquitis

PubMed Health : 64 About acute bronchitis: In acute bronchitis, the lower airways (bronchi) are temporarily inflamed. The inflammation is usually caused by cold viruses, so it often occurs together with other symptoms of a cold.Acute bronchitis causes a cough which might not go away for a while, even after the cold has gone away. Although the cough may be unpleasant and persistent, in otherwise healthy people it usually isn’t anything serious. The symptoms then go away on their own after a few weeks. Treatment with medication usually isn’t necessary. Some medications may help relieve the symptoms a bit.

Wikipedia : 77 Bronchitis is an inflammation of the bronchi (large and medium-sized airways) in the lungs. Symptoms... more...

Sources

Related Diseases for Bronchitis

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Diseases related to Bronchitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 414)
# Related Disease Score Top Affiliating Genes
1 sinusitis 30.8 CFTR CXCL8 IL5 RNASE3
2 hypereosinophilic syndrome 30.6 CCL11 IL5 RNASE3
3 pulmonary emphysema 30.5 ELANE SERPINA1 SERPINB1
4 bronchial disease 30.5 CCL11 CCR3 CXCL8 ELANE IL5 IL6
5 bronchiectasis 30.4 CFTR CXCL8 ELANE MPO SERPINA1
6 avian influenza 30.4 CXCL8 IL6 TNF
7 rhinitis 30.3 CCL11 CXCL8 IL5 RNASE3 VIP
8 microscopic polyangiitis 30.1 MPO TNF
9 pulmonary eosinophilia 30.1 CCL11 IL5 RNASE3
10 status asthmaticus 30.1 CXCL8 ELANE IL5 RNASE3
11 allergic asthma 30.1 CCL11 IL5 RNASE3
12 chlamydia 30.1 CRP CXCL8 IL6 TNF
13 food allergy 30.1 ALB IL5 RNASE3
14 allergic rhinitis 30.0 CCL11 CXCL8 IL5 MPO RNASE3 VIP
15 chronic eosinophilic pneumonia 30.0 CCL11 IL5 RNASE3
16 eosinophilic pneumonia 30.0 CCL11 IL5 RNASE3
17 common cold 30.0 ALB CCL11 CXCL8 IL5 RNASE3
18 aspergillosis 30.0 CFTR ELANE IL5 TNF
19 bronchopulmonary dysplasia 29.9 CXCL8 ELANE RNASE3
20 pertussis 29.9 IL6 TNF VIP
21 pneumoconiosis 29.9 CXCL8 IL6 SERPINA1 TNF
22 bronchiolitis 29.9 CCL11 CRP CXCL8 IL5 IL6 RNASE3
23 bronchiolitis obliterans 29.9 CXCL8 IL6 TNF
24 tonsillitis 29.9 CXCL8 IL6 TNF
25 interstitial lung disease 29.9 CXCL8 IL6 TNF
26 eosinophilic gastroenteritis 29.8 ALB CCL11 IL5 RNASE3
27 pneumonia 29.8 CCL11 CRP CXCL8 ELANE IL5 IL6
28 heart disease 29.7 ALB CRP CXCL8 IL6 TNF
29 colitis 29.6 CXCL8 IL6 MPO TNF
30 acute respiratory distress syndrome 29.6 CXCL8 ELANE IL6 TNF
31 pulmonary disease, chronic obstructive 29.6 CCL11 CCR3 CFTR CRP CXCL8 ELANE
32 bacterial pneumonia 29.6 CRP CXCL8 ELANE IL6 LACTB
33 protein-energy malnutrition 29.5 ALB IL6 TNF
34 respiratory failure 29.5 ALB CRP CXCL8 ELANE SERPINA1 TNF
35 acute cystitis 29.5 ALB CRP CXCL8 IL6
36 cystic fibrosis 29.5 CFTR CXCL8 ELANE MPO RNASE3 SERPINA1
37 bacterial infectious disease 29.4 CFTR CRP CXCL8 ELANE IL6 TNF
38 typhoid fever 29.4 ALB CFTR CRP IL6 TNF
39 dermatitis, atopic 29.4 CCL11 CCR3 CXCL8 IL5 RNASE3 TNF
40 severe acute respiratory syndrome 29.3 CRP CXCL8 TNF
41 alpha-1-antitrypsin deficiency 29.3 ALB CXCL8 ELANE SERPINA1
42 ulcerative colitis 29.3 CRP CXCL8 IL6 MPO TNF
43 myocardial infarction 29.3 ALB CRP IL6 MPO TNF
44 pyelonephritis 29.2 ALB CRP CXCL8 IL6 TNF
45 esophagitis 29.2 CCL11 CCR3 CXCL8 IL5 IL6
46 otitis media 29.2 ALB CCL11 CXCL8 IL6 LACTB RNASE3
47 asthma 29.2 CCL11 CCR3 CFTR CXCL8 ELANE IL5
48 gastroenteritis 29.1 ALB CCL11 CRP CXCL8 IL5 IL6
49 appendicitis 28.9 ALB CRP CXCL8 IL6 MPO TNF
50 vasculitis 28.5 CRP ELANE MPO SERPINA1 SERPINB1 TNF

Comorbidity relations with Bronchitis via Phenotypic Disease Network (PDN): (show top 50) (show all 128)


Acquired Polycythemia Active Peptic Ulcer Disease
Acute Conjunctivitis Acute Cor Pulmonale
Acute Cystitis Acute Ethmoiditis
Acute Frontal Sinusitis Acute Kidney Failure
Acute Maxillary Sinusitis Agammaglobulinemia, X-Linked
Allergic Rhinitis Alzheimer Disease
Anthracosis Anxiety
Aortic Valve Disease 1 Asbestosis
Aspergillosis Asthma
Atrophic Gastritis Benign Essential Hypertension
Bronchiectasis Bronchopneumonia
Cardiac Arrest Cerebral Atherosclerosis
Cerebral Degeneration Cerebrovascular Disease
Chronic Ethmoiditis Chronic Frontal Sinusitis
Chronic Kidney Failure Chronic Laryngitis
Chronic Maxillary Sinusitis Chronic Myocardial Ischemia
Chronic Pulmonary Heart Disease Chronic Rhinitis
Conjunctivitis Conn's Syndrome
Cystitis Decubitus Ulcer
Deficiency Anemia Diabetic Polyneuropathy
Diaphragm Disease Duodenitis
Dyskinesia of Esophagus Dysthymic Disorder
Encephalopathy Esophageal Candidiasis
Esophageal Disease Esophagitis
Familial Atrial Fibrillation First-Degree Atrioventricular Block

Graphical network of the top 20 diseases related to Bronchitis:



Diseases related to Bronchitis
Sources

Symptoms & Phenotypes for Bronchitis

About this section

Symptoms:

12
  • • cough
  • • shortness of breath
  • • chest tightness
  • • low fever

UMLS symptoms related to Bronchitis:


fever, pruritus, recurrent pharyngitis, snoring, coughing

MGI Mouse Phenotypes related to Bronchitis:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10 CCL11 CCR3 CFTR ELANE IL5 IL6
2 homeostasis/metabolism MP:0005376 9.93 ALB CCR3 CFTR CRP ELANE IL5
3 immune system MP:0005387 9.73 CCL11 CCR3 CFTR CRP ELANE IL5
4 respiratory system MP:0005388 9.23 CCL11 CCR3 CFTR IL5 IL6 SERPINB1
Sources

Drugs & Therapeutics for Bronchitis

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PubMedHealth treatment related to Bronchitis: 64

Acute bronchitis gets better on its own without treatment. If you feel weak and ill, it’s best to take it easy for a few days. This also means not doing any sports or other strenuous physical activities. Hot tea or broth is usually considered to have a soothing effect. But there is no scientific proof that drinking a lot more fluids than usual helps, or doesn’t help.Acute bronchitis doesn’t need to be treated with medication. Drugs such as paracetamol (acetaminophen) or ibuprofen are sometimes a good idea, though, for the relief of cold symptoms such as fever and pain.There hasn’t been enough research on the effectiveness of cough medicines that are designed to make you cough less (cough suppressants) or make it easier to cough up phlegm (expectorants). Because coughing has the important function of getting rid of mucus and foreign objects, cough suppressants should only be used for a limited amount of time, and only for really unpleasant, dry coughs that disrupt your sleep. Herbal medicines might relieve coughs somewhat.Because the symptoms are usually caused by viruses, antibiotics don’t help much in the treatment of acute bronchitis. But they can have side effects and contribute to bacteria becoming resistant. So antibiotics aren’t recommended as a treatment for acute bronchitis.

FDA approved drugs:

(show all 6)
# Drug Name Active Ingredient(s) 19 Company Approval Date
1
Augmentin 19 AMOXICILLIN; CLAVULANATE POTASSIUM SmithKline Beecham February 1996
2
Avelox I.V. 19 MOXIFLOXACIN HYDROCHLORIDE Bayer November 2001
3
Biaxin XL 19 CLARITHROMYCIN Abbott Laboratories March 2000
4
Cedax 19 CEFTIBUTEN DIHYDRATE Schering-Plough December 1995
5
Ceftin 19 CEFUROXIME AXETIL GlaxoSmithKline September 1997
6
Tequin 19 Bristol-Myers Squibb December, 1999

Drugs for Bronchitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 399)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Terbutaline Approved Phase 4 23031-25-6 5403
2
Budesonide Approved Phase 4,Phase 2,Phase 1 51333-22-3 63006 5281004
3
Montelukast Approved Phase 4,Phase 3,Phase 2,Not Applicable 158966-92-8 5281040
4
Bromhexine Approved Phase 4 3572-43-8
5
Racepinephrine Approved Phase 4,Phase 3,Phase 2,Not Applicable 329-65-7 838
6
Epinephrine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 51-43-4 5816
7
Azithromycin Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 83905-01-5 55185 447043
8
Levofloxacin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 100986-85-4 149096
9
Ofloxacin Approved Phase 4,Phase 3,Phase 2,Phase 1 82419-36-1 4583
10
Fluticasone Approved, Experimental Phase 4,Phase 3,Phase 2,Not Applicable 90566-53-3 62924
11
Acetylcysteine Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 616-91-1 12035
12
Etanercept Approved, Investigational Phase 4,Phase 1,Phase 2 185243-69-0
13
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 50-02-2 5743
14
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 1177-87-3
15
Polyestradiol phosphate Approved Phase 4,Phase 3 28014-46-2
16
Amoxicillin Approved, Vet_approved Phase 4,Phase 3 26787-78-0 33613
17
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 3 50-28-2 5757
18
Ethinyl Estradiol Approved Phase 4,Phase 3 57-63-6 5991
19
Clavulanate Approved, Vet_approved Phase 4,Phase 3,Not Applicable 58001-44-8 5280980
20
Norgestimate Approved, Investigational Phase 4,Phase 3 35189-28-7 6540478
21
Moxifloxacin Approved, Investigational Phase 4,Phase 3 354812-41-2, 151096-09-2 152946
22
Telithromycin Approved Phase 4 191114-48-4 70789201 5462516
23
Cefuroxime Approved Phase 4,Phase 3,Not Applicable 55268-75-2 5361202 5479529
24
Guaifenesin Approved, Investigational, Vet_approved Phase 4,Phase 3 93-14-1 3516
25
Pseudoephedrine Approved Phase 4,Phase 3,Phase 2,Not Applicable 90-82-4 7028
26
Ephedrine Approved Phase 4,Phase 3,Phase 2,Not Applicable 299-42-3 9294
27
Erythromycin Approved, Investigational, Vet_approved Phase 4 114-07-8 12560 441411
28
Clarithromycin Approved Phase 4,Phase 3 81103-11-9 84029
29
Doxycycline Approved, Investigational, Vet_approved Phase 4 564-25-0 54671203
30
Losartan Approved Phase 4,Not Applicable 114798-26-4 3961
31
Angiotensin II Approved, Investigational Phase 4,Not Applicable 68521-88-0, 11128-99-7, 4474-91-3 172198 65143
32
Norflurane Approved, Experimental Phase 4,Not Applicable 811-97-2
33
leucovorin Approved Phase 4,Phase 2,Phase 1 58-05-9 6006 143
34
Trimethoprim Approved, Vet_approved Phase 4 738-70-5 5578
35
Sulfamethoxazole Approved Phase 4 723-46-6 5329
36
Sodium Citrate Approved, Investigational Phase 4,Not Applicable 68-04-2
37
Zinc Approved, Investigational Phase 4,Phase 3,Not Applicable 7440-66-6 32051
38
Acetazolamide Approved, Vet_approved Phase 4 59-66-5 1986
39
Aztreonam Approved Phase 4 78110-38-0 5742832 5362041
40
Mechlorethamine Approved, Investigational Phase 4,Phase 2,Phase 3 51-75-2 4033
41
Methylprednisolone hemisuccinate Approved Phase 4,Not Applicable 2921-57-5
42
Methylprednisolone Approved, Vet_approved Phase 4,Not Applicable 83-43-2 6741
43
Prednisolone phosphate Approved, Vet_approved Phase 4,Not Applicable 302-25-0
44
Prednisolone Approved, Vet_approved Phase 4,Not Applicable 50-24-8 5755
45
Ibuprofen Approved Phase 4 15687-27-1 3672
46
Acetaminophen Approved Phase 4 103-90-2 1983
47
Ipratropium Approved Phase 4,Not Applicable 60205-81-4, 22254-24-6 43232 657309
48
Prednisone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 53-03-2 5865
49
Oseltamivir Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 204255-11-8, 196618-13-0 65028
50
Codeine Approved, Illicit Phase 4 76-57-3 5284371

Interventional clinical trials:

(show top 50) (show all 720)
# Name Status NCT ID Phase Drugs
1 The Effect of Bronchodilator on Eosinophilic Bronchitis and Cough Variant Asthma Unknown status NCT02002754 Phase 4 Bambuterol Hydrochloride tablets
2 Therapeutic Effect of Different Treatment Course With Inhaled Corticosteroids in Eosinophilic Bronchitis Patients Unknown status NCT02002715 Phase 4 Inhaled budesonide
3 Evaluate the Efficacy and Safety of Andrographolide Sulfonate in Patients With Acute Bronchitis Unknown status NCT03132623 Phase 4 andrographolide sulfonate;andrographolide sulfonate simulation
4 A Study of Andrographolide Sulfonate in Patients With Acute Exacerbation of Chronic Bronchitis Unknown status NCT03132610 Phase 4 andrographolide sulfonate;andrographolide sulfonate simulation
5 Efficacy and Safety of add-on Montelukast to Inhaled Budesonide in the Treatment of Nonasthmatic Eosinophilic Bronchitis Unknown status NCT01121016 Phase 4 Montelukast
6 Randomized, Double-blind, Placebo-controlled Study to Evaluate the Effect of Roflumilast on Endothelial Function in Patients With Chronic Obstructive Pulmonary Disease Unknown status NCT01595750 Phase 4 Roflumilast 500;Placebo
7 Effects of Exercise Training on Systemic Inflammation an Muscle Repair According to the Obstructive Chronic Pulmonary Disease (COPD) Phenotype Unknown status NCT01431625 Phase 4
8 Use of Roflumilast to Prevent Exacerbations in Fibrotic Sarcoidosis Patients (REFS) Unknown status NCT01830959 Phase 4 Roflumilast;Placebo
9 Sunovion Brovana Versus Serevent Inspiratory Capacity High Resolution Computed Tomography Unknown status NCT01361984 Phase 4 Nebulized arformoterol;Salmeterol
10 Small Airways Evaluation and Treatment Unknown status NCT02526758 Phase 4 beclomethasone;formoterol;budesonide
11 Optimizing Influenza Vaccination in Surgical Oncology Patients Unknown status NCT01698177 Phase 4
12 Effect of Vitamin D Supplementation in Young South African Children Hospitalized With Acute Lower Respiratory Infection Unknown status NCT02054182 Phase 4 Vitamin D
13 High Flow Nasal Cannula vs Low Flow Oxygen Therapy in Bronchiolitis Unknown status NCT03015051 Phase 4 Oxygen
14 Home Oxygen Therapy in Bronchiolitis Unknown status NCT01216553 Phase 4
15 Bronchiolitis All-study, SE-Norway Unknown status NCT00817466 Phase 4 Racemic adrenaline;Isotonic saline
16 Evaluate the Efficacy and Safety of Andrographolide Sulfonate in Patients With Acute Tonsillitis Unknown status NCT03134443 Phase 4 Andrographolide sulfonate;Andrographolide sulfonate simulation
17 Study Regarding the Clinical Efficacy of Synatura® in Patients With Chronic Bronchitis Type COPD Completed NCT03623282 Phase 4 Synatura® 15 mL
18 Moxifloxacin Versus Amoxicillin Clavulanic Acid in Treatment of Acute Exacerbation of Chronic Bronchitis Completed NCT00656747 Phase 4 Avelox (Moxifloxacin, BAY12-8039);Amoxicillin clavulanic acid
19 Mucolytic Effectiveness of Tacholiquine ® in Chronic Bronchitis Completed NCT02515799 Phase 4 Tacholiquine
20 The Effectiveness of Roflumilast in Improving Mucociliary Clearance in Patients With COPD and Chronic Bronchitis Completed NCT03073798 Phase 4 Roflumilast;Placebo
21 Telithromycin: in the Treatment of Acute Exacerbation of Chronic Bronchitis in Adult Outpatients With COPD Completed NCT00538148 Phase 4 Telithromycin
22 PERSPECTIVE: Telithromycin - Acute Exacerbation of Chronic Bronchitis Completed NCT00132938 Phase 4 telithromycin
23 Study of Azithromycin for Lymphocytic Bronchiolitis/Bronchitis After Lung Transplantation Completed NCT01109160 Phase 4 Azithromycin Dihydrate
24 Ceftidoren Versus Levofloxacin in the Treatment of Patients With Acute Exacerbations of Chronic Bronchitis (AECB) Completed NCT01467297 Phase 4 ceftidoren;levofloxacin
25 Ketek in CAP / AECB in Ambulatory Adult Patients Completed NCT00546676 Phase 4 Telithromycin
26 Airway Clearance for Prevention of Chronic Obstructive Pulmonary Disease (COPD) Exacerbation Completed NCT00181207 Phase 4
27 Efficacy Safety Study of Arformoterol/Tiotropium Combination Versus Either Therapy Alone in Chronic Obstructive Pulmonary Disease (COPD) Completed NCT00424528 Phase 4 Arformoterol Tartrate Inhalation Solution;Tiotropium;Arformoterol and Tiotropium;Placebo
28 Relative Potency of Inhaled Corticosteroids Completed NCT00292838 Phase 4 fluticasone 25, 50, 100, 200 mcg
29 Phase 4 Study - Mucinex D as Adjunct Therapy Completed NCT00441246 Phase 4 Mucinex D (600 mg guaifenesin and 60 mg pseudoephedrine HCl extended-release bi-layer tablets)
30 Effect of Addition Oral Montelukast to Standard Treatment in Acute Asthma in Hospitalized Preschool Children Completed NCT03369119 Phase 4 Montelukast 4 Mg Oral Granule;Placebos
31 Chronic Obstructive Pulmonary Disease (COPD) Post-hospitalization Study Completed NCT01110200 Phase 4 ADVAIR DISKUS 250/50 mg BID;SEREVENT 50 mcg BID
32 Add-on Effects of Tiotropium Over Formoterol in Exercise Tolerance on Chronic Obstructive Pulmonary Disease Patients Completed NCT00680056 Phase 4 Formoterol plus Placebo (Tiotropium);Formoterol plus Tiotropium
33 COPD on Primary Care Treatment (COOPT) Completed NCT00184977 Phase 4 N-acetylcysteine;fluticasone propionate
34 Aizthromycin or Clarithromycin in H-pylori Eradication Regimen Completed NCT01667692 Phase 4 azithromycin;clarithmycin
35 Inhaled Steroid Reduces Systemic Inflammation in COPD Completed NCT00175565 Phase 4 inhaled fluticasone 500 mcg b.i.d.
36 Clinical Trial for the Assessment of Delayed Antibiotic Treatment in Pediatric (DAP-Pediatrics) Completed NCT01800747 Phase 4
37 Roflumilast on Markers of Bone Metabolism and Endothelial Function in COPD Completed NCT01745848 Phase 4 Roflumilast
38 BENEFITS OF ACLIDINIUM BROMIDE IN THE RELIEF OF COPD SYMPTOMS INCLUDING COUGH Completed NCT02375724 Phase 4 Aclidinium Bromide;Placebo
39 Placebo Versus Antibiotics in Acute Exacerbations of Chronic Obstructive Pulmonary Disease (COPD) Completed NCT00170222 Phase 4 doxycycline
40 Study of Enbrel in Rheumatoid Arthritis (RA) Subjects With Comorbid Disorders Completed NCT00132418 Phase 4 Enbrel;Placebo
41 Efficacy of Losartan in Preventing Progression of COPD Completed NCT00720226 Phase 4 Losartan;Placebo
42 Change of Inspiratory Peak Flow in COPD Completed NCT00561886 Phase 4 Formoterol
43 Advair HFA For Chronic Obstructive Pulmonary Disease(COPD) Completed NCT00633217 Phase 4 Fluticasone Propionate/Salmeterol DISKUS 250/50mcg;Fluticasone Propionate/Salmeterol Hydrofluoroalkane 134a MDI 230/42mcg
44 Telithromycin in Respiratory Tract Infections Completed NCT00261105 Phase 4 telithromycin
45 A Clinical Trial to Evaluate the Efficacy and Safety of YMC026 in Respiratory Disease Patients Completed NCT03334916 Phase 4 YMC026;Placebo
46 Roflumilast in Chronic Obstructive Pulmonary Disease (COPD) Patients Treated With Fixed Combinations of Long-acting β2-agonists (LABA) and Inhaled Glucocorticosteroid (ICS) Completed NCT01329029 Phase 4 Roflumilast;Placebo
47 Effect of Weight and/or Obesity on Sulfamethoxazole and Trimethoprim Concentrations Completed NCT01167452 Phase 4 Sulfamethoxazole/trimethoprim
48 Proteomic Profiling for Influenza Completed NCT00133588 Phase 4
49 Clinical Trial for the Assessment of Delayed Antibiotic Treatment Strategies Completed NCT01363531 Phase 4
50 Effectiveness of Different Exercise Training Programs to the Profile of COPD Patients Completed NCT01336283 Phase 4

Search NIH Clinical Center for Bronchitis

Inferred drug relations via UMLS 74 / NDF-RT 52 :


Cochrane evidence based reviews: bronchitis

Sources

Genetic Tests for Bronchitis

About this section

Genetic tests related to Bronchitis:

# Genetic test Affiliating Genes
1 Chronic Bronchitis 30
Sources

Anatomical Context for Bronchitis

About this section

MalaCards organs/tissues related to Bronchitis:

42
Lung, Testes, Heart, Skin, Bone, Tonsil, Kidney
Sources

Publications for Bronchitis

About this section

Articles related to Bronchitis:

(show top 50) (show all 4470)
# Title Authors Year
1
Chicken anaemia virus enhances and prolongs subsequent avian influenza (H9N2) and infectious bronchitis viral infections. ( 30827377 )
2019
2
Improved quality of life associated with long-term use of guaifenesin in a patient with chronic obstructive pulmonary disease (COPD) & stable chronic bronchitis: A case report. ( 30450278 )
2019
3
Mechanisms of bergenin treatment on chronic bronchitis analyzed by liquid chromatography-tandem mass spectrometry based on metabolomics. ( 30551484 )
2019
4
Identification and formation mechanism of a novel noncoding RNA produced by avian infectious bronchitis virus. ( 30616206 )
2019
5
Gonadal pathogenicity of an infectious bronchitis virus strain from the Massachusetts genotype. ( 30637657 )
2019
6
Genetic and biological characteristics of four novel recombinant avian infectious bronchitis viruses isolated in China. ( 30641197 )
2019
7
Acute Bronchitis Caused by Bordetella Pertussis Possibly Co-Infected with Mycoplasma Pneumoniae. ( 30643110 )
2019
8
Multiple respiratory microbiota profiles are associated with lower airway inflammation in children with protracted bacterial bronchitis. ( 30660785 )
2019
9
Among All Miners, Coal Miners Demonstrate A Disproportionately High Prevalence of Obstructive Spirometric Abnormality and Chronic Bronchitis. ( 30688766 )
2019
10
Effect of experimental Ornithobacterium rhinotracheale infection along with live infectious bronchitis vaccination in broiler chickens. ( 30690611 )
2019
11
Occupational exposures and incidence of chronic bronchitis and related symptoms over two decades: the European Community Respiratory Health Survey. ( 30700596 )
2019
12
Mucus Hydration in Subjects with Stable Chronic Bronchitis: A Comparison of Spontaneous and Induced Sputum. ( 30712400 )
2019
13
Near-Complete Genome Sequence of Infectious Bronchitis Virus Strain VFAR-047 (GI-16 Lineage), Isolated in Peru. ( 30714035 )
2019
14
Hydrogen sulfide donor NaHS causes bronchitis with enhanced respiratory secretion in rats. ( 30726810 )
2019
15
The 3D8 single chain variable fragment protein suppress infectious bronchitis virus transmission in the transgenic chickens. ( 30738233 )
2019
16
Development of a recombinant Newcastle disease virus-vectored vaccine for infectious bronchitis virus variant strains circulating in Egypt. ( 30744668 )
2019
17
Genetic and antigenic heterogeneity of infectious bronchitis virus in South America: implications for control programs. ( 30761909 )
2019
18
Immunoprofiling of peripheral blood from infectious bronchitis virus vaccinated MHC-B chicken lines - Monocyte MHC-II expression as a potential correlate of protection. ( 30763593 )
2019
19
Incidence and Longitudinal Changes in Prevalence of Chronic Bronchitis in Farm and Non-Farm Rural Residents of Saskatchewan. ( 30789445 )
2019
20
Novel genotype of infectious bronchitis virus isolated in China. ( 30827386 )
2019
21
Repeated avian infectious bronchitis virus infections within a single chicken farm. ( 30828040 )
2019
22
A pilot study of safety of sulfamethoxazole, trimethoprim and guaifenesin in pediatric and adult patients with acute bronchitis. ( 30832720 )
2019
23
Ectoine-Containing Inhalation Solution versus Saline Inhalation Solution in the Treatment of Acute Bronchitis and Acute Respiratory Infections: A Prospective, Controlled, Observational Study. ( 30834276 )
2019
24
Quantitative Assessment of Mucociliary Clearance in Smokers with Mild-to-Moderate Chronic Obstructive Pulmonary Disease and Chronic Bronchitis from Planar Radionuclide Imaging Using the Change in Penetration Index. ( 30848685 )
2019
25
Gene signatures common to allograft rejection are associated with lymphocytic bronchitis. ( 30849195 )
2019
26
N-Linked glycosylation of the membrane protein ectodomain regulates infectious bronchitis virus-induced ER stress response, apoptosis and pathogenesis. ( 30852271 )
2019
27
The Infectious Bronchitis Coronavirus Envelope Protein Alters Golgi pH to Protect Spike Protein and Promote Release of Infectious Virus. ( 30867314 )
2019
28
Memory immune responses and protection of chickens against a nephropathogenic infectious bronchitis virus strain by combining live heterologous and inactivated homologous vaccines. ( 30867350 )
2019
29
Construction and Immunogenicity of Novel Chimeric Virus-Like Particles Bearing Antigens of Infectious Bronchitis Virus and Newcastle Disease Virus. ( 30871190 )
2019
30
Chronic bronchitis: High prevalence in never smokers and underdiagnosis- A population-based study in Colombia. ( 29669432 )
2019
31
Molecular characterization of whole genome sequence of infectious bronchitis virus 624I genotype confirms the close relationship with Q1 genotype. ( 30126059 )
2019
32
Efficacy and safety of GHX02 in the treatment of acute bronchitis: protocol of a phase II, double-blind, randomised placebo-controlled trial. ( 29764875 )
2018
33
Innate antiviral immune response against infectious bronchitis virus and involvement of prostaglandin E2 in the uterine mucosa of laying hens. ( 29407895 )
2018
34
Successful Treatment of Protein-Losing Enteropathy and Plastic Bronchitis by Biphasic Cuirass Ventilation in a Patient with Failing Fontan Circulation. ( 29794380 )
2018
35
Acute phase proteins and stress markers in the immediate response to a combined vaccination against Newcastle disease and infectious bronchitis viruses in specific pathogen free (SPF) layer chicks. ( 29182756 )
2018
36
Exposure to traffic-related air pollution and acute bronchitis in children: season and age as modifiers. ( 29440305 )
2018
37
Perception and Awareness of chronic obstructive pulmonary disease, Chronic Bronchitis and Pulmonary Emphysema in the Spanish Urban Population. ( 29428681 )
2018
38
Non-astmatic Eosinophilic Bronchitis. ( 29404185 )
2018
39
An underestimated cause of chronic cough: The Protracted Bacterial Bronchitis. ( 29387250 )
2018
40
Induction of innate host responses characterized by production of interleukin (IL)-1I^ and recruitment of macrophages to the respiratory tract of chickens following infection with infectious bronchitis virus (IBV). ( 29426399 )
2018
41
Plastic bronchitis associated with adenovirus infection. ( 29582774 )
2018
42
Viral interference between low pathogenic avian influenza H9N2 and avian infectious bronchitis viruses in vitro and in ovo. ( 29940196 )
2018
43
Echocardiographic characteristics in Fontan patients before the onset of protein-losing enteropathy or plastic bronchitis. ( 29082544 )
2018
44
In with acute bronchitis; out with duodenal perforation: the potentially harmful cascade of over-testing. A case report. ( 29441163 )
2018
45
Inappropriate Antibiotic Prescribing for Acute Bronchitis in Children and Impact on Subsequent Episodes of Care and Treatment. ( 29794648 )
2018
46
Induction of innate immune response following introduction of infectious bronchitis virus (IBV) in the trachea and renal tissues of chickens. ( 29330060 )
2018
47
Seroprevalence and genotyping of avian infectious bronchitis virus detected from Iranian unvaccinated backyard chickens. ( 29922421 )
2018
48
Using Multinomial and Space-Time Permutation Models to Understand the Epidemiology of Infectious Bronchitis in California Between 2008 and 2012. ( 29944405 )
2018
49
Rapid development and evaluation of a live-attenuated QX-like infectious bronchitis virus vaccine. ( 29891352 )
2018
50
An adult case of plastic bronchitis: a rare and multifactorial disease. ( 29600096 )
2018