Bronchitis

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Disease Ontology 11 DOID:6132 ICD9CM 34 466.0 490 491 MeSH 43 D001991 D029481 NCIt 49 C26722 C26932 C2911 SNOMED-CT 68 155512004 155566007 32398004

ICD10 31 J20 J20.0 J20.1 J20.2 J20.3 J20.4 J20.5 J20.6 J20.7 J20.8 J20.9 J40 J42 more EFO 16 EFO_0006505 EFO_0009661 ICD11 33 1050848854 11753425 11753425/other 11753425/unspecified 1242562217 1296842178 1542022084 290835130 290835130/other 290835130/unspecified 671608920 727572936 727572936/other 727572936/unspecified 971074877 more UMLS 71 C0006277 C0008677 C0149514 C0149725 C0238990 more

MedlinePlus: ⁴¹ Bronchitis is an inflammation of the bronchial tubes, the airways that carry air to your lungs. It causes a cough that often brings up mucus. It can also cause shortness of breath, wheezing, a low fever, and chest tightness. There are two main types of bronchitis: acute and chronic. Most cases of acute bronchitis get better within several days. But your cough can last for several weeks after the infection is gone. The same viruses that cause colds and the flu often cause acute bronchitis. These viruses spread through the air when people cough, or though physical contact (for example, on unwashed hands). Being exposed to tobacco smoke, air pollution, dusts, vapors, and fumes can also cause acute bronchitis. Less often, bacteria can also cause acute bronchitis. To diagnose acute bronchitis, your health care provider will ask about your symptoms and listen to your breathing. You may also have other tests. Treatments include rest, fluids, and aspirin (for adults) or acetaminophen to treat fever. A humidifier or steam can also help. You may need inhaled medicine to open your airways if you are wheezing. Antibiotics won't help if the cause is viral. You may get antibiotics if the cause is bacterial. NIH: National Heart, Lung, and Blood Institute

MalaCards based summary: Bronchitis, also known as chronic bronchitis, is related to allergic asthma and haemophilus influenzae, and has symptoms including cough, chest tightness and shortness of breath. An important gene associated with Bronchitis is ELANE (Elastase, Neutrophil Expressed), and among its related pathways/superpathways are Signal Transduction and Innate Immune System. The drugs Cefdinir and Streptokinase have been mentioned in the context of this disorder. Affiliated tissues include lung, heart and t cells, and related phenotypes are immune system and hematopoietic system

PubMed Health : ⁶³ Acute bronchitis: In acute bronchitis, the lower airways (bronchi) are temporarily inflamed. The inflammation is usually caused by cold viruses, so it often occurs together with other symptoms of a cold. Acute bronchitis causes a cough which might not go away for a while, even after the cold has gone away. Although the cough may be unpleasant and persistent, in otherwise healthy people it usually isn’t anything serious. The symptoms then go away on their own after a few weeks. Treatment with medication usually isn’t necessary. Some medications may help relieve the symptoms a bit.

CDC: ² Bronchitis occurs when the airways of the lungs swell and produce mucus. That's what makes you cough. Acute bronchitis, often called a "chest cold," is the most common type of bronchitis. The symptoms last less than 3 weeks. Antibiotics are not indicated to treat acute bronchitis. Using antibiotics when not needed could do more harm than good. If you're a healthy person without underlying heart or lung problems or a weakened immune system, this information is for you.

Disease Ontology: ¹¹ A bronchial disease that is an inflammation of the bronchial tubes. It is caused by bacteria and viruses. The disease has symptom cough with mucus, has symptom shortness of breath, has symptom low fever and has symptom chest tightness.

Wikipedia: ⁷⁵ Bronchitis is inflammation of the bronchi (large and medium-sized airways) in the lungs that causes... more...

#	Description	GenomeRNAi Source Accession	Score	Top Affiliating Genes
1	no effect	GR00402-S-1	10.18	CCL11 CFTR CRP CXCL8 DDX1 ELANE
2	no effect	GR00402-S-2	10.18	CCL11 CFTR CRP DDX1 ELANE IL5

Acute bronchitis gets better on its own without treatment . If you feel weak and ill, it’s best to take it easy for a few days. This also means not doing any sports or other strenuous physical activities. Hot tea or broth is usually considered to have a soothing effect. But there is no scientific proof that drinking a lot more fluids than usual helps, or doesn’t help. Acute bronchitis doesn’t need to be treated with medication. Drugs such as paracetamol (acetaminophen ) or ibuprofen are sometimes a good idea, though, for the relief of cold symptoms such as fever and pain. There hasn’t been enough research on the effectiveness of cough medicines that are designed to make you cough less (cough suppressants) or make it easier to cough up phlegm (expectorants). Because coughing has the important function of getting rid of mucus and foreign objects, cough suppressants should only be used for a limited amount of time, and only for really unpleasant, dry coughs that disrupt your sleep . Herbal medicines might relieve coughs somewhat. Because the symptoms are usually caused by viruses , antibiotics don’t help much in the treatment of acute bronchitis . But they can have side effects and contribute to bacteria becoming resistant. So antibiotics aren’t recommended as a treatment for acute bronchitis.

Search NIH Clinical Center for Bronchitis

Acetylcysteine Aminophylline aminophylline dihydrate AMINOPHYLLINE PWDR cefditoren CEFTIBUTEN DIHYDRATE Dornase Alfa fenugreek seed meal Fenugreek seed preparation FENUGREEK SEED PWDR gemifloxacin mesylate

Guaifenesin iodinated glycerol Ipratropium Ipratropium Bromide lomefloxacin oxtriphylline Theophylline Theophylline anhydrous Theophylline calcium salicylate Theophylline Sodium Glycinate TRIMETHOPRIM SULFATE

Search GEO for disease gene expression data for Bronchitis.