Aliases & Classifications for Bronchopneumonia

MalaCards integrated aliases for Bronchopneumonia:

Name: Bronchopneumonia 12 45 15 17 74
Lobular Pneumonia 12 74
Chest Infection - Bronchopneumonia 12
Bronchial Pneumonia 12

Classifications:



External Ids:

Disease Ontology 12 DOID:12375
ICD9CM 36 485
MeSH 45 D001996
NCIt 51 C26710
SNOMED-CT 69 67814005
ICD10 34 J18.0

Summaries for Bronchopneumonia

Disease Ontology : 12 A pneumonia involving inflammation of lungs that begins in the terminal bronchioles, which become clogged with thick mucus that forms consolidated patches in adjacent lobules. It is caused by bacteria and viruses.

MalaCards based summary : Bronchopneumonia, also known as lobular pneumonia, is related to netherton syndrome and pleural empyema, and has symptoms including bronchopneumopathy An important gene associated with Bronchopneumonia is HP (Haptoglobin), and among its related pathways/superpathways is amb2 Integrin signaling. The drugs Magnesium oxide and Magnesium citrate have been mentioned in the context of this disorder. Affiliated tissues include lung, kidney and heart.

Wikipedia : 77 Pneumonia is an inflammatory condition of the lung affecting primarily the small air sacs known as... more...

Related Diseases for Bronchopneumonia

Diseases related to Bronchopneumonia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 109)
# Related Disease Score Top Affiliating Genes
1 netherton syndrome 31.9 ELANE PI3
2 pleural empyema 30.3 HSF4 P3H2
3 intellectual disability - hypoplastic corpus callosum - preauricular tag 11.2
4 pneumonia 10.3
5 cerebral aneurysms 10.3 ELANE MPO
6 pasteurellosis 10.3 ELANE MPO
7 rapidly progressive glomerulonephritis 10.3 ELANE MPO
8 scarlet fever 10.2 HSF4 P3H2
9 influenza 10.2
10 periodontosis 10.2 ELANE MPO
11 suppurative lymphadenitis 10.2 HSF4 P3H2
12 farmer's lung 10.2 ELANE PI3
13 pulmonary aspergilloma 10.2 MPO P3H2
14 aleukemic leukemia cutis 10.2 ELANE MPO
15 pustular psoriasis 10.2 ELANE PI3
16 amyotrophic lateral sclerosis 8 10.2 VAPA VAPB
17 erysipelas 10.2 ELANE PI3
18 amyotrophic lateral sclerosis type 14 10.2 VAPA VAPB
19 pneumothorax 10.2
20 impetigo herpetiformis 10.2 ELANE PI3
21 measles 10.1
22 chediak-higashi syndrome 10.1 GUSB MPO
23 vulvitis 10.1 ELANE HSF4 MPO
24 pertussis 10.1
25 bronchitis 10.1
26 acute respiratory distress syndrome 10.1 ELANE PI3
27 pulmonary edema 10.0
28 arteriosclerosis 10.0
29 haemophilus influenzae 10.0
30 impetigo 10.0 ELANE HSF4 PI3
31 leukemia 9.9
32 endocarditis 9.9
33 heart disease 9.9
34 bronchiolitis 9.9
35 uremia 9.9
36 herpes simplex 9.9
37 meningitis 9.9
38 lung disease 9.9 ELANE MPO PI3
39 vascular disease 9.9 ELANE HP MPO
40 pleurisy 9.9
41 extrinsic allergic alveolitis 9.8 MPO PI3
42 leukemia, chronic lymphocytic 2 9.8
43 breast cancer 9.8
44 intussusception 9.8
45 leukemia, chronic lymphocytic 9.8
46 ataxia-telangiectasia 9.8
47 premature centromere division 9.8
48 chondrosarcoma 9.8
49 cystic fibrosis 9.8
50 myeloma, multiple 9.8

Comorbidity relations with Bronchopneumonia via Phenotypic Disease Network (PDN): (show all 33)


Active Peptic Ulcer Disease Acute Cystitis
Acute Kidney Failure Alzheimer Disease
Anxiety Bronchiectasis
Bronchitis Cerebral Atherosclerosis
Chronic Kidney Failure Chronic Myocardial Ischemia
Chronic Pulmonary Heart Disease Decubitus Ulcer
Deficiency Anemia Esophagitis
Familial Atrial Fibrillation Generalized Atherosclerosis
Heart Disease Hypothyroidism
Idiopathic Interstitial Pneumonia Iron Deficiency Anemia
Ischemic Heart Disease Kidney Disease
Oral Candidiasis Osteoporosis
Paralytic Ileus Parkinson Disease, Late-Onset
Peripheral Vascular Disease Postinflammatory Pulmonary Fibrosis
Protein-Energy Malnutrition Respiratory Failure
Schizophreniform Disorder Swallowing Disorders
Transient Cerebral Ischemia

Graphical network of the top 20 diseases related to Bronchopneumonia:



Diseases related to Bronchopneumonia

Symptoms & Phenotypes for Bronchopneumonia

UMLS symptoms related to Bronchopneumonia:


bronchopneumopathy

Drugs & Therapeutics for Bronchopneumonia

Drugs for Bronchopneumonia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 39)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Magnesium oxide Approved Phase 4 1309-48-4 14792
2
Magnesium citrate Approved Phase 4 3344-18-1
3
Sodium Citrate Approved, Investigational Phase 4 68-04-2
4
Ganciclovir Approved, Investigational Phase 4 82410-32-0 3454
5
Acyclovir Approved Phase 4 59277-89-3 2022
6
Calcium Approved, Nutraceutical Phase 4 7440-70-2 271
7
Citric Acid Approved, Nutraceutical, Vet_approved Phase 4 77-92-9 311
8 Picosulfate sodium Phase 4
9 Laxatives Phase 4
10 Anticoagulants Phase 4
11 Chelating Agents Phase 4
12 Gastrointestinal Agents Phase 4
13 Cathartics Phase 4
14 Anti-Ulcer Agents Phase 4
15 Antacids Phase 4
16 Citrate Phase 4
17 Calcium, Dietary Phase 4
18 Antibiotics, Antitubercular Phase 4,Not Applicable
19 Antitubercular Agents Phase 4,Not Applicable
20 Anti-Infective Agents Phase 4,Not Applicable
21 Anti-Bacterial Agents Phase 4,Not Applicable
22 Antiviral Agents Phase 4
23 Nucleic Acid Synthesis Inhibitors Phase 4
24 Ganciclovir triphosphate Phase 4
25 Heptavalent Pneumococcal Conjugate Vaccine Phase 2, Phase 3
26 Vaccines Phase 2, Phase 3
27 Immunologic Factors Phase 2, Phase 3
28
Chlorhexidine Approved, Vet_approved 55-56-1 2713 9552079
29
Benzocaine Approved, Investigational Not Applicable 1994-09-7, 94-09-7 2337
30
tannic acid Approved Not Applicable 1401-55-4
31 Anti-Inflammatory Agents, Non-Steroidal
32 Peripheral Nervous System Agents
33 Analgesics, Non-Narcotic
34 Anti-Inflammatory Agents
35 Antirheumatic Agents
36 Analgesics
37 Chlorhexidine gluconate
38 Complement System Proteins Not Applicable
39 Vasoconstrictor Agents Not Applicable

Interventional clinical trials:

(show all 13)
# Name Status NCT ID Phase Drugs
1 Efficacy and Safety of Split-dose Citrafleet Administered From 2 to 6 Hours Before Morning Colonoscopies Unknown status NCT01481714 Phase 4 Sodium picosulphate, magnesium oxid and citric acid;Sodium picosulphate/magnesium oxide and citric acid
2 Duration of Antibiotic Therapy in Community - Acquired Pneumonia Unknown status NCT01492387 Phase 4
3 PTH - Preemptive Treatment for Herpesviridae Unknown status NCT02152358 Phase 4 Aciclovir;Ganciclovir;Placebo
4 Evaluation of a Vaccine for Reducing Ear and Lung Infections in Children Completed NCT01545375 Phase 2, Phase 3
5 E. Coli Nissle 1917 - Suspension for Infection Prophylaxis Active, not recruiting NCT02802059 Phase 3 EcN-Suspension;Placebo
6 Evaluation of the Treatment With Klacid®SR in Patients With Lower Respiratory Tract Infection Completed NCT01108185
7 Use of Non Steroidal Antiinflammatory Drugs in Patients With Community Acquired Pneumonia Completed NCT02523885
8 A Sputum Screening Test to Rule-out Pneumonia at an Early Stage Completed NCT03256604
9 DiagNostic Study of Low-dose CT and multipleX PCR on Antibiotic Treatment and Outcome of Community-Acquired Pneumonia Recruiting NCT03360851 Not Applicable
10 Nosocomial Bacterial and Fungal Chest Infections in Cirrhotic Patients Not yet recruiting NCT03413293
11 Effect of Assisted Autogenic Drainage In Children Suffering From Pneumonia Not yet recruiting NCT03710759 Not Applicable
12 Impact of Early Goal-directed Fluid Therapy in Septic Patients Undergoing Emergency Surgery Terminated NCT01654003 Not Applicable
13 Impact of Early Goal-directed Fluid Therapy in Hypovolemic Patients Undergoing Emergency Surgery Terminated NCT01653977 Not Applicable

Search NIH Clinical Center for Bronchopneumonia

Cochrane evidence based reviews: bronchopneumonia

Genetic Tests for Bronchopneumonia

Anatomical Context for Bronchopneumonia

MalaCards organs/tissues related to Bronchopneumonia:

42
Lung, Kidney, Heart, Testes, Liver, Spleen, Bone

Publications for Bronchopneumonia

Articles related to Bronchopneumonia:

(show top 50) (show all 336)
# Title Authors Year
1
Association of lung lesions measured by thoracic ultrasonography at first diagnosis of bronchopneumonia with relapse rate and growth performance in feedlot cattle. ( 30901138 )
2019
2
An Outbreak of Fatal Bordetella bronchiseptica Bronchopneumonia in Puppies. ( 30898296 )
2019
3
Ophthalmologic findings associated with Rhodococcus equi bronchopneumonia in foals. ( 30706641 )
2019
4
Fatal bronchopneumonia caused by skunk adenovirus 1 in an African pygmy hedgehog. ( 30475680 )
2019
5
Brain abscess and bronchopneumonia caused by Acinetobacter baumannii in a 2-year-old female sheep. ( 30375283 )
2018
6
Bronchopneumonia in Swedish lambs: a study of pathological changes and bacteriological agents. ( 30223865 )
2018
7
Inter-rater agreement and reliability of thoracic ultrasonographic findings in feedlot calves, with or without naturally occurring bronchopneumonia. ( 30133838 )
2018
8
Luteolin alleviates LPS-induced bronchopneumonia injury in vitro and in vivo by down-regulating microRNA-132 expression. ( 30119240 )
2018
9
Distinct bacterial metacommunities inhabit the upper and lower respiratory tracts of healthy feedlot cattle and those diagnosed with bronchopneumonia. ( 29981695 )
2018
10
In vivo efficacy and pharmacokinetics of bi-aryl oxazolidinone RBx 11760 loaded polylactic acid-polyethylene glycol nanoparticles in mouse hematogenous bronchopneumonia and rat groin abscess caused by Staphylococcus aureus. ( 29524496 )
2018
11
Respiratory Mites ( Orthohalarachne diminuata) and β-hemolytic Streptococci-Associated Bronchopneumonia Outbreak in South American Fur Seal Pups ( Arctocephalus australis). ( 29369727 )
2018
12
SimBaby Plus Standardized Patient Teaching Model in the Teaching of Cases of Acute and Severe Bronchopneumonia in Infancy. ( 26414638 )
2017
13
Fatal fibrino-hemorrhagic bronchopneumonia associated with Morganella morganii in a bottlenose dolphin: a case report. ( 29256426 )
2017
14
Case report: Severe and progressive bronchopneumonia by Aelurostrongylus abstrusus in an adopted stray cat from Portugal. ( 29114129 )
2017
15
Comparative therapeutic effect of steroidal and non-steroidal anti-inflammatory drugs on pro-inflammatory cytokine production in water buffalo calves (Bubalus bubalis) naturally infected with bronchopneumonia: a randomized clinical trial. ( 28831754 )
2017
16
Bronchopneumonia associated with Mannheimia granulomatis infection in a Belgian hare ( Lepus europaeus). ( 28482756 )
2017
17
Efficacy of Tulathromycin for the Treatment of Foals with Mild to Moderate Bronchopneumonia. ( 28421633 )
2017
18
Corynebacterium propinquum bronchopneumonia in a child with ataxia telangiectasia. ( 28621102 )
2016
19
H7N9 Live Attenuated Influenza Vaccine Is Highly Immunogenic, Prevents Virus Replication, and Protects Against Severe Bronchopneumonia in Ferrets. ( 26796670 )
2016
20
Evaluation of Drug Treatment of Bronchopneumonia at the Pediatric Clinic in Sarajevo. ( 27594741 )
2016
21
Giant solitary ancient schwannoma of the pleura masquerading as bronchopneumonia. ( 27578943 )
2016
22
Incremental Value (Bayesian Framework) of Thoracic Ultrasonography over Thoracic Auscultation for Diagnosis of Bronchopneumonia in Preweaned Dairy Calves. ( 27305277 )
2016
23
Clinical Assessment of a Point-of-Care Serum Amyloid A Assay in Foals with Bronchopneumonia. ( 27296082 )
2016
24
Advanced chronic lymphoid leukemia with severe bronchopneumonia: an Autopsy Case Report. ( 27284536 )
2016
25
Circulating immune complexes of calves with bronchopneumonia modulate the function of peripheral blood leukocytes: In vitro evaluation. ( 27234551 )
2016
26
Aspiration pneumonia and bronchopneumonia in progressive supranuclear palsy treated with qing fei tang: two case reports. ( 25889685 )
2015
27
Profiles of serum amino acids to screen for catabolic and inflammation status in calves with Mycoplasma bronchopneumonia. ( 25342635 )
2015
28
Splenic abscess as a potential initial manifestation of quiescent infective endocarditis in a patient with bronchopneumonia. ( 25564586 )
2015
29
Efficacy of gamithromycin for the treatment of foals with mild to moderate bronchopneumonia. ( 25619521 )
2015
30
Sepsis due to Erysipelothrix rhusiopathiae in a patient with chronic lymphocytic leukemia associated with bronchopneumonia due to Pseudomonas aeruginosa and Escherichia coli: A case report. ( 26015797 )
2015
31
Pathology in practice. Primary ciliary dyskinesia (PCD) with associated bronchopneumonia, bronchiectasis, and hydrocephalus in a dog. ( 24479455 )
2014
32
A case of masquerading bronchopneumonia. ( 24778483 )
2014
33
Acute die-off of chamois (Rupicapra rupicapra) in the Eastern Austrian Alps due to bacterial bronchopneumonia with Pasteurellaceae. ( 24807183 )
2014
34
Cellular immunity profile in children with congenital heart disease and bronchopneumonia: evaluation of lymphocyte subsets and regulatory T cells. ( 26155168 )
2014
35
Bronchopneumonia in wild boar (Sus scrofa) caused by Rhodococcus equi carrying the VapB type 8 plasmid. ( 23531380 )
2013
36
Bronchopneumonia caused by Corynebacterium pseudodiphtheriticum. ( 23955623 )
2013
37
Rapidly vanishing lung pseudotumor in a patient with acute bilateral bronchopneumonia. ( 24266319 )
2013
38
Spontaneous pneumothorax associated with Aspergillus bronchopneumonia in a dog. ( 24304839 )
2013
39
Serum SP-D levels as a biomarker of lung injury in children suffering of bronchopneumonia. ( 22662592 )
2012
40
Bronchopneumonia in two dairy calves associated with Mannheimia species cluster V infection. ( 22956485 )
2012
41
Interleukin 12 receptor deficiency in a child with recurrent bronchopneumonia and very high IgE levels. ( 22992471 )
2012
42
Evidence that calf bronchopneumonia may be accompanied by increased sialylation of circulating immune complexes' IgG. ( 23068275 )
2012
43
Therapeutic drug monitoring of gentamicin in patients with bronchopneumonia: cost considerations and patient outcomes. ( 25610196 )
2012
44
Helcococcus ovis isolated from a goat with purulent bronchopneumonia and pulmonary abscesses. ( 22362961 )
2012
45
Comparison of antemortem antimicrobial treatment regimens to antimicrobial susceptibility patterns of postmortem lung isolates from feedlot cattle with bronchopneumonia. ( 22362524 )
2012
46
Analysis of trace and major elements in bronchoalveolar lavage fluid of Mycoplasma bronchopneumonia in calves. ( 21870151 )
2012
47
Fatal bronchopneumonia in a Metastrongylus elongatus and Porcine circovirus type 2 co-infected pig. ( 21669448 )
2012
48
Pneumomediastinum and subcutaneous emphysema in a cat associated with necrotizing bronchopneumonia caused by feline herpesvirus-1. ( 22467969 )
2011
49
Thrombosis of the cranial vena cava in a cow with bronchopneumonia and traumatic reticuloperitonitis. ( 22547845 )
2011
50
Impact of isoflupredone acetate treatment on clinical signs and weight gain in weanling heifers with experimentally induced Mannheimia haemolytica bronchopneumonia. ( 22126689 )
2011

Variations for Bronchopneumonia

Expression for Bronchopneumonia

Search GEO for disease gene expression data for Bronchopneumonia.

Pathways for Bronchopneumonia

Pathways related to Bronchopneumonia according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.48 ELANE HP MPO

GO Terms for Bronchopneumonia

Cellular components related to Bronchopneumonia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 endoplasmic reticulum exit site GO:0070971 8.96 VAPA VAPB
2 azurophil granule lumen GO:0035578 8.8 ELANE GUSB MPO

Biological processes related to Bronchopneumonia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 defense response to bacterium GO:0042742 9.61 ELANE HP MPO
2 defense response GO:0006952 9.5 HP MPO TPSAB1
3 sphingolipid biosynthetic process GO:0030148 9.46 VAPA VAPB
4 endoplasmic reticulum organization GO:0007029 9.4 VAPA VAPB
5 defense response to fungus GO:0050832 9.37 ELANE MPO
6 neutrophil degranulation GO:0043312 9.35 ELANE GUSB HP MPO VAPA
7 negative regulation of growth of symbiont in host GO:0044130 9.26 ELANE MPO
8 COPII-coated vesicle budding GO:0090114 9.16 VAPA VAPB
9 response to yeast GO:0001878 8.62 ELANE MPO

Molecular functions related to Bronchopneumonia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein domain specific binding GO:0019904 9.43 GUSB MYO1D VAPA
2 serine-type endopeptidase activity GO:0004252 9.33 ELANE HP TPSAB1
3 cytokine binding GO:0019955 8.96 ELANE IL12RB1
4 FFAT motif binding GO:0033149 8.62 VAPA VAPB

Sources for Bronchopneumonia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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