BRGDA9
MCID: BRG012
MIFTS: 31
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Brugada Syndrome 9 (BRGDA9)
Categories:
Blood diseases, Cardiovascular diseases, Genetic diseases, Rare diseases, Respiratory diseases
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MalaCards integrated aliases for Brugada Syndrome 9:
Characteristics:HPO:31Classifications:
MalaCards categories:
Global: Genetic diseases Rare diseases Anatomical: Cardiovascular diseases Respiratory diseases Blood diseases
ICD10:
32
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OMIM :
56
Brugada syndrome is characterized by ST segment elevation in the right precordial electrocardiogram leads (so-called type 1 ECG) and a high incidence of sudden death in patients with structurally normal hearts. The syndrome typically manifests during adulthood, with a mean age of sudden death of 41 +/- 15 years, but also occurs in infants and children (summary by Antzelevitch et al., 2005).
For a discussion of genetic heterogeneity of Brugada syndrome, see BRGDA1 (601144). (616399)
MalaCards based summary : Brugada Syndrome 9, also known as brgda9, is related to spinocerebellar ataxia type 19/22 and brugada syndrome. An important gene associated with Brugada Syndrome 9 is KCND3 (Potassium Voltage-Gated Channel Subfamily D Member 3), and among its related pathways/superpathways are Cell cycle_Spindle assembly and chromosome separation and Signal transduction_PKA signaling. Affiliated tissues include heart, and related phenotypes are palpitations and st segment elevation Disease Ontology : 12 A Brugada syndrome that has material basis in heterozygous mutation in the KCND3 gene on chromosome 1p13. UniProtKB/Swiss-Prot : 73 Brugada syndrome 9: A tachyarrhythmia characterized by right bundle branch block and ST segment elevation on an electrocardiogram (ECG). It can cause the ventricles to beat so fast that the blood is prevented from circulating efficiently in the body. When this situation occurs, the individual will faint and may die in a few minutes if the heart is not reset. |
Diseases in the Brugada Syndrome family:
Diseases related to Brugada Syndrome 9 via text searches within MalaCards or GeneCards Suite gene sharing:
Graphical network of the top 20 diseases related to Brugada Syndrome 9:![]() |
Human phenotypes related to Brugada Syndrome 9:31
Symptoms via clinical synopsis from OMIM:56Clinical features from OMIM:616399GenomeRNAi Phenotypes related to Brugada Syndrome 9 according to GeneCards Suite gene sharing:26
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MalaCards organs/tissues related to Brugada Syndrome 9:40
Heart
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Articles related to Brugada Syndrome 9:
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ClinVar genetic disease variations for Brugada Syndrome 9:6
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Search
GEO
for disease gene expression data for Brugada Syndrome 9.
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Cellular components related to Brugada Syndrome 9 according to GeneCards Suite gene sharing:
Biological processes related to Brugada Syndrome 9 according to GeneCards Suite gene sharing:
Molecular functions related to Brugada Syndrome 9 according to GeneCards Suite gene sharing:
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