MCID: BLL012
MIFTS: 37

Bullous Impetigo

Categories: Infectious diseases, Rare diseases, Skin diseases

Aliases & Classifications for Bullous Impetigo

MalaCards integrated aliases for Bullous Impetigo:

Name: Bullous Impetigo 60 56 74

Characteristics:

Orphanet epidemiological data:

60
bullous impetigo
Inheritance: Not applicable; Age of onset: All ages; Age of death: normal life expectancy;

Classifications:



Summaries for Bullous Impetigo

MalaCards based summary : Bullous Impetigo is related to ritter's disease and impetigo. An important gene associated with Bullous Impetigo is DSG1 (Desmoglein 1), and among its related pathways/superpathways are Pathways in cancer and Apoptotic cleavage of cellular proteins. Affiliated tissues include skin, and related phenotypes are abnormal blistering of the skin and erythema

Wikipedia : 77 Bullous Impetigo is a skin condition that characteristically occurs in the newborn, and is caused by a... more...

Related Diseases for Bullous Impetigo

Diseases related to Bullous Impetigo via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 42)
# Related Disease Score Top Affiliating Genes
1 ritter's disease 32.0 DSG1 EDNRA EDNRB
2 impetigo 31.9 CALCA DSG1 EDNRB IL6
3 pemphigus 30.7 DSG1 DSG3
4 pemphigus foliaceus 30.3 DSG1 DSG3
5 recessive dystrophic epidermolysis bullosa-generalized other 11.3
6 miliaria rubra 10.2
7 miliaria 10.2
8 herpes simplex 10.1
9 diabetic foot ulcers 10.1 CALCA IL6
10 acute cholangitis 10.1 CALCA IL6
11 esophagitis 10.1 DSG1 IL6
12 herpetiform pemphigus 10.1 DSG1 DSG3
13 nodular goiter 10.1 CALCA IL6
14 complex regional pain syndrome 10.1 CALCA IL6
15 bone resorption disease 10.0 CALCA IL6
16 bullous skin disease 10.0 DSG1 DSG3
17 bacterial pneumonia 10.0 CALCA IL6
18 cellulitis 10.0 DSG1 DSG3
19 subcorneal pustular dermatosis 10.0 DSG1 DSG3
20 paraneoplastic pemphigus 10.0 DSG1 DSG3
21 dermatitis, atopic 10.0
22 toxic shock syndrome 10.0
23 dermatitis 10.0
24 neonatal herpes 10.0
25 pyogenic granuloma 10.0
26 streptococcal toxic-shock syndrome 10.0
27 pemphigus vulgaris 10.0 DSG1 DSG3
28 bullous pemphigoid 10.0 DSG1 DSG3
29 perinephritis 9.9 EDNRA EDNRB
30 migraine with or without aura 1 9.9 CALCA EDNRA
31 scarlet fever 9.9 EDNRA EDNRB
32 radiation proctitis 9.9 EDNRA EDNRB
33 multiple endocrine neoplasia, type iib 9.9 CALCA EDNRB
34 autonomic nervous system disease 9.9 CALCA EDNRB
35 intestinal disease 9.8 EDNRB IL6
36 constipation 9.8 CALCA EDNRB
37 thyroid carcinoma, familial medullary 9.7 CALCA EDNRB
38 commensal bacterial infectious disease 9.7 DSG1 EDNRB IL6
39 thyroid cancer, nonmedullary, 2 9.7 CALCA EDNRB
40 connective tissue disease 9.6 EDNRA EDNRB IL6
41 cystic kidney disease 9.6 EDNRA EDNRB
42 autosomal dominant polycystic kidney disease 9.5 EDNRA EDNRB

Graphical network of the top 20 diseases related to Bullous Impetigo:



Diseases related to Bullous Impetigo

Symptoms & Phenotypes for Bullous Impetigo

Human phenotypes related to Bullous Impetigo:

60 33 (show all 8)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 abnormal blistering of the skin 60 33 hallmark (90%) Very frequent (99-80%) HP:0008066
2 erythema 60 33 hallmark (90%) Very frequent (99-80%) HP:0010783
3 recurrent bacterial skin infections 60 33 hallmark (90%) Very frequent (99-80%) HP:0005406
4 pustule 60 33 hallmark (90%) Very frequent (99-80%) HP:0200039
5 glomerulopathy 60 33 occasional (7.5%) Occasional (29-5%) HP:0100820
6 abnormality of the lymphatic system 60 33 occasional (7.5%) Occasional (29-5%) HP:0100763
7 sepsis 60 33 occasional (7.5%) Occasional (29-5%) HP:0100806
8 septic arthritis 60 33 occasional (7.5%) Occasional (29-5%) HP:0003095

MGI Mouse Phenotypes related to Bullous Impetigo:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 integument MP:0010771 9.65 DSG1 DSG3 EDNRA EDNRB IL6
2 digestive/alimentary MP:0005381 9.62 DSG3 EDNRA EDNRB IL6
3 respiratory system MP:0005388 9.46 DSG3 EDNRA EDNRB IL6
4 skeleton MP:0005390 9.35 DSG1 DSG3 EDNRA EDNRB IL6
5 vision/eye MP:0005391 9.02 DSG1 DSG3 EDNRA EDNRB IL6

Drugs & Therapeutics for Bullous Impetigo

Search Clinical Trials , NIH Clinical Center for Bullous Impetigo

Genetic Tests for Bullous Impetigo

Anatomical Context for Bullous Impetigo

MalaCards organs/tissues related to Bullous Impetigo:

42
Skin

Publications for Bullous Impetigo

Articles related to Bullous Impetigo:

(show top 50) (show all 56)
# Title Authors Year
1
Concurrent pyogenic granuloma and bullous impetigo of a pregnant woman's finger. ( 28329529 )
2017
2
Bullous impetigo during interstitial pneumonitis. ( 29050448 )
2017
3
Staphylococcal bullous impetigo in a neonate. ( 27458596 )
2016
4
Bullous impetigo and pregnancy: Case report and review of blistering conditions in pregnancy. ( 27617460 )
2016
5
Case of bullous impetigo with enormous bulla developing into staphylococcal scalded skin syndrome. ( 26603272 )
2016
6
Bullous Impetigo Rapid Diagnostic and Therapeutic Quiz: A Model for Assessing Basic Dermatology Knowledge of Primary Care Providers. ( 27599660 )
2016
7
Bullous impetigo. ( 24736928 )
2014
8
Value of serum procalcitonin and interleukin-6 in patients with bullous impetigo and staphylococcal scalded skin syndrome. ( 25298068 )
2014
9
Paediatric bullous dermatoses. Linear immunoglobulin A (IgA) dermatosis. Bullous impetigo. Bullous insect bite reaction. Neonatal Herpes simplex virus (HSV) infection. ( 23111154 )
2013
10
The use of typing methods and infection prevention measures to control a bullous impetigo outbreak on a neonatal ward. ( 23168170 )
2012
11
Bullous impetigo associated with Abiotrophia defectiva in an immunocompetent adult. ( 22493280 )
2012
12
Outbreak of bullous impetigo caused by Staphylococcus aureus strains of phage type 3C/71 in a maternity ward linked to nasal carriage of a healthcare worker. ( 22378195 )
2012
13
Bullous impetigo in children infected with methicillin-resistant Staphylococcus aureus alone or in combination with methicillin-susceptible S. aureus: analysis of genetic characteristics, including assessment of exfoliative toxin gene carriage. ( 21430094 )
2011
14
Dermacase. Bullous impetigo. ( 18272632 )
2008
15
Outbreak of staphylococcal bullous impetigo in a maternity ward linked to an asymptomatic healthcare worker. ( 17945394 )
2007
16
Is blistering distal dactylitis a variant of bullous impetigo? ( 17362240 )
2007
17
Bullous impetigo: a rare presentation in fulminant streptococcal toxic shock syndrome. ( 17505275 )
2007
18
Pemphigus, bullous impetigo, and the staphylococcal scalded-skin syndrome. ( 17065642 )
2006
19
Bullous impetigo of the face after epilation by threading. ( 16172329 )
2005
20
Review: topical mupirocin or fusidic acid may be more effective than oral antibiotics for limited non-bullous impetigo. ( 15688485 )
2005
21
Generalized bullous impetigo in a neonate. ( 15575854 )
2004
22
Desmosomes and disease: pemphigus and bullous impetigo. ( 15363804 )
2004
23
Treatment of bullous impetigo and the staphylococcal scalded skin syndrome in infants. ( 15482208 )
2004
24
Clinicopathological case 3: pemphigus foliaceus; bullous impetigo; subcorneal pustular dermatoses. ( 12823325 )
2003
25
Confocal laser scanning microscopic observation of glycocalyx production by Staphylococcus aureus in skin lesions of bullous impetigo, atopic dermatitis and pemphigus foliaceus. ( 12653745 )
2003
26
Clonal association of Staphylococcus aureus causing bullous impetigo and the emergence of new methicillin-resistant clonal groups in Kansai district in Japan. ( 11992289 )
2002
27
Molecular mechanisms of blister formation in bullous impetigo and staphylococcal scalded skin syndrome. ( 12093888 )
2002
28
Toxin in bullous impetigo and staphylococcal scalded-skin syndrome targets desmoglein 1. ( 11062541 )
2000
29
Bullous impetigo. ( 9369884 )
1997
30
Vesicles and bulla in an infant. Bullous varicella (chicken pox complicated by bullous impetigo). ( 8285728 )
1994
31
Bullous impetigo caused by group A streptococci. A case report. ( 1350146 )
1992
32
Bullous impetigo in homosexual men--a risk marker for HIV-1 infection? ( 1607190 )
1992
33
Is penicillin still the drug of choice for non-bullous impetigo? ( 1681172 )
1991
34
Bullous impetigo and localized scalded skin syndrome in the elderly. ( 3623889 )
1987
35
An epidemic of bullous impetigo in a newborn nursery due to Staphylococcus aureus: epidemiology and control measures. ( 3565708 )
1986
36
Antibiotic susceptibilities of Staphylococcus aureus strains derived from furuncle and bullous impetigo. ( 3894459 )
1985
37
Effects of serum albumin on coagulase release from Staphylococcus aureus derived from bullous impetigo. ( 6386912 )
1984
38
Epidemic bullous impetigo in a nursery due to a nasal carrier of Staphylococcus aureus: role of epidemiology and control measures. ( 6376403 )
1984
39
Vacuoles in the upper part of the epidermis as a clue to eventuation of superficial pemphigus and bullous impetigo. ( 6731731 )
1984
40
What histologic finding distinguishes superficial pemphigus and bullous impetigo? ( 6375421 )
1984
41
Re-emergence of bullous impetigo. ( 6799136 )
1982
42
Sequential bullous impetigo and cutaneous Herpes simplex virus infection. ( 6761658 )
1982
43
Falsely normal direct immunofluorescent microscopic fundings in bullous impetigo. ( 7027964 )
1981
44
Re-emergence of bullous impetigo. ( 6799044 )
1981
45
Bullous impetigo caused by Streptococcus salivarius: a case report. ( 7002959 )
1980
46
The epidermolytic toxin of Staphylococcus aureus: its failure to bind to cells and its detection in blister fluids of patients with bullous impetigo. ( 701847 )
1978
47
Staphylococcal scalded skin syndrome. II. Serum level of anti exfoliatin and anti alpha-toxin in patients with staphylococcal scalded skin syndrome or bullous impetigo. ( 15461328 )
1977
48
Bullous impetigo. Occurrence of localized scalded skin syndrome in an adult. ( 782365 )
1976
49
Skin complications of heroin addiction. Bullous impetigo. ( 4513637 )
1973
50
An epidemic of bullous impetigo arising from a central admission-observation nursery. ( 5059306 )
1972

Variations for Bullous Impetigo

Expression for Bullous Impetigo

Search GEO for disease gene expression data for Bullous Impetigo.

Pathways for Bullous Impetigo

GO Terms for Bullous Impetigo

Cellular components related to Bullous Impetigo according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cornified envelope GO:0001533 8.96 DSG1 DSG3
2 desmosome GO:0030057 8.62 DSG1 DSG3

Biological processes related to Bullous Impetigo according to GeneCards Suite gene sharing:

(show all 11)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of cytosolic calcium ion concentration GO:0007204 9.5 CALCA EDNRA EDNRB
2 cornification GO:0070268 9.49 DSG1 DSG3
3 monocyte chemotaxis GO:0002548 9.48 CALCA IL6
4 activation of adenylate cyclase activity GO:0007190 9.46 CALCA EDNRA
5 response to pain GO:0048265 9.43 CALCA EDNRB
6 vasodilation GO:0042311 9.4 CALCA EDNRB
7 vasoconstriction GO:0042310 9.37 EDNRA EDNRB
8 negative regulation of bone resorption GO:0045779 9.26 CALCA IL6
9 enteric nervous system development GO:0048484 9.16 EDNRA EDNRB
10 regulation of blood pressure GO:0008217 9.13 CALCA EDNRA EDNRB
11 endothelin receptor signaling pathway GO:0086100 8.62 EDNRA EDNRB

Molecular functions related to Bullous Impetigo according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 endothelin receptor activity GO:0004962 8.62 EDNRA EDNRB

Sources for Bullous Impetigo

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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