Aliases & Classifications for Bullous Keratopathy

MalaCards integrated aliases for Bullous Keratopathy:

Name: Bullous Keratopathy 12 56 15 74

Classifications:



External Ids:

Disease Ontology 12 DOID:11031
ICD9CM 36 371.23
NCIt 51 C26970
SNOMED-CT 69 57207003
ICD10 34 H18.1
UMLS 74 C0155111

Summaries for Bullous Keratopathy

MalaCards based summary : Bullous Keratopathy is related to keratopathy and cataract, and has symptoms including swelling of eye An important gene associated with Bullous Keratopathy is TNC (Tenascin C), and among its related pathways/superpathways are ERK Signaling and PAK Pathway. The drugs Pharmaceutical Solutions and Ophthalmic Solutions have been mentioned in the context of this disorder. Affiliated tissues include endothelial, eye and skin, and related phenotypes are cardiovascular system and craniofacial

Wikipedia : 77 Bullous keratopathy is a pathological condition in which small vesicles, or bullae, are formed in the... more...

Related Diseases for Bullous Keratopathy

Diseases related to Bullous Keratopathy via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 53, show less)
# Related Disease Score Top Affiliating Genes
1 keratopathy 31.2 FBN1 IL1A NID1 TGFB2 TNC
2 cataract 10.4
3 corneal dystrophy, fuchs endothelial, 1 10.3
4 fuchs' endothelial dystrophy 10.3
5 stiff skin syndrome 10.3 FBN1 TGFB2
6 loeys-dietz syndrome 3 10.2 FBN1 TGFB2
7 corneal dystrophy, posterior polymorphous, 3 10.2 BMP4 TGFB2
8 char syndrome 10.2 BMP4 FBN1
9 cryptogenic organizing pneumonia 10.2 CXCL8 TNC
10 keratitis, hereditary 10.2
11 keratoconus 10.2
12 corneal disease 10.2
13 leukoregulin 10.2 CXCL8 IL1A
14 scabies 10.2 CXCL8 IL1A
15 sebaceous gland disease 10.1 CXCL8 IL1A
16 radiculopathy 10.1 CXCL8 IL1A
17 macular holes 10.1 CXCL8 TGFB2
18 pulpitis 10.1 CXCL8 IL1A
19 oral candidiasis 10.1 CXCL8 IL1A
20 astigmatism 10.1
21 macular retinal edema 10.1
22 herpes simplex 10.1
23 loeys-dietz syndrome 1 10.1 FBN1 TGFB2
24 synovial chondromatosis 10.1 BMP2 BMP4
25 fibrochondrogenesis 10.1 BMP2 BMP4
26 osseous heteroplasia, progressive 10.1 BMP2 BMP4
27 bacterial sepsis 10.0 CXCL8 SELE
28 osteochondroma 10.0 BMP2 TGFB2
29 pulmonary hypertension, primary, 1 10.0 BMP2 FBN1
30 otosclerosis 10.0 BMP2 BMP4
31 aniridia 1 9.9
32 macular dystrophy, dominant cystoid 9.9
33 corneal endothelial dystrophy 9.9
34 insulin-like growth factor i 9.9
35 werner syndrome 9.9
36 open-angle glaucoma 9.9
37 corneal edema 9.9
38 myopia 9.9
39 corneal ulcer 9.9
40 refractive error 9.9
41 cytokine deficiency 9.9
42 farsightedness 9.9
43 endotheliitis 9.9
44 essential iris atrophy 9.9
45 contact dermatitis 9.9 CXCL8 IL1A SELE
46 proteasome-associated autoinflammatory syndrome 1 9.9 CXCL8 IL1A SELE
47 pilomatrixoma 9.9 BMP2 BMP4
48 bacterial vaginosis 9.9 CXCL8 IL1A
49 hydrarthrosis 9.9 AQP3 MIP
50 skin disease 9.9 CXCL8 IL1A SELE
51 osteomyelitis 9.8 BMP2 CXCL8 IL1A
52 lipoid proteinosis of urbach and wiethe 9.8 FBN1 NID1
53 malaria 9.7 CXCL8 IL1A SELE TGFB2

Comorbidity relations with Bullous Keratopathy via Phenotypic Disease Network (PDN): (showing 4, show less)


Corneal Degeneration Corneal Edema
Corneal Endothelial Dystrophy Corneal Ulcer

Graphical network of the top 20 diseases related to Bullous Keratopathy:



Diseases related to Bullous Keratopathy

Symptoms & Phenotypes for Bullous Keratopathy

UMLS symptoms related to Bullous Keratopathy:


swelling of eye

MGI Mouse Phenotypes related to Bullous Keratopathy:

47 (showing 5, show less)
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.92 AQP3 BMP2 BMP4 FBN1 IL1A NID1
2 craniofacial MP:0005382 9.65 AQP3 BMP2 BMP4 FBN1 TGFB2
3 homeostasis/metabolism MP:0005376 9.56 AQP3 BMP2 BMP4 FBN1 IL1A SELE
4 hearing/vestibular/ear MP:0005377 9.55 AQP3 BMP2 BMP4 TGFB2 TNC
5 vision/eye MP:0005391 9.1 AQP3 BMP4 MIP NID1 SELE TGFB2

Drugs & Therapeutics for Bullous Keratopathy

Drugs for Bullous Keratopathy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(showing 48, show less)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Pharmaceutical Solutions Phase 3,Phase 2,Not Applicable
2 Ophthalmic Solutions Phase 3
3
Prednisolone phosphate Approved, Vet_approved Phase 2 302-25-0
4
Methylprednisolone hemisuccinate Approved Phase 2 2921-57-5
5
Prednisolone Approved, Vet_approved Phase 2 50-24-8 5755
6
Methylprednisolone Approved, Vet_approved Phase 2 83-43-2 6741
7
Fluorometholone Approved, Investigational Phase 2,Not Applicable 426-13-1 9878
8
Bevacizumab Approved, Investigational Phase 2 216974-75-3
9
Prednisolone hemisuccinate Experimental Phase 2 2920-86-7
10 Anesthetics Phase 2
11 Hormones Phase 2,Not Applicable
12 Hormone Antagonists Phase 2,Not Applicable
13 Autonomic Agents Phase 2,Not Applicable
14 Antiemetics Phase 2,Not Applicable
15 Methylprednisolone Acetate Phase 2
16 glucocorticoids Phase 2,Not Applicable
17 Gastrointestinal Agents Phase 2,Not Applicable
18 Anti-Allergic Agents Phase 2
19 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 2,Not Applicable
20 Antineoplastic Agents, Hormonal Phase 2,Not Applicable
21 Peripheral Nervous System Agents Phase 2,Not Applicable
22 Protective Agents Phase 2
23 Prednisolone acetate Phase 2
24 Anti-Inflammatory Agents Phase 2,Not Applicable
25 Neuroprotective Agents Phase 2
26 Endothelial Growth Factors Phase 2
27 Angiogenesis Modulating Agents Phase 2
28 Angiogenesis Inhibitors Phase 2
29 Mitogens Phase 2
30 Antineoplastic Agents, Immunological Phase 2
31
Dipivefrin Approved Not Applicable 52365-63-6 3105
32
Folic Acid Approved, Nutraceutical, Vet_approved Not Applicable 59-30-3 6037
33
Riboflavin Approved, Investigational, Nutraceutical, Vet_approved Not Applicable 83-88-5 493570
34 Photosensitizing Agents Not Applicable
35 Dermatologic Agents Not Applicable
36 Vitamin B Complex Not Applicable
37 Vitamins Not Applicable
38 Trace Elements Not Applicable
39 Micronutrients Not Applicable
40 Vitamin B2 Not Applicable
41 Folate Not Applicable
42 Nutrients Not Applicable
43 Vitamin B9 Not Applicable
44 Alkylating Agents Not Applicable
45 Anti-Bacterial Agents Not Applicable
46 Antibiotics, Antitubercular Not Applicable
47 Nucleic Acid Synthesis Inhibitors Not Applicable
48 Mitomycins Not Applicable

Interventional clinical trials:

(showing 19, show less)
# Name Status NCT ID Phase Drugs
1 Trial of Netarsudil for Prevention of Corticosteroid-induced Intraocular Pressure Elevation Active, not recruiting NCT03248037 Phase 3 Netarsudil;Placebo
2 Amniotic Membrane Graft In Syntomathic Bullous Keratopathy Completed NCT01926535 Phase 2
3 Comparison of Two Steroid Regimens to Prevent Transplant Rejection After Corneal Transplant (DMEK) Completed NCT01448213 Phase 2 Prednisolone acetate;Fluorometholone
4 Pain and Visual Outcome in Intravitreal Bevacizumab Injection Completed NCT02790775 Phase 2 Anti-VEGF in quadrant 1;Anti-VEGF in quadrant 2;Anti-VEGF in quadrant 3;Anti-VEGF in quadrant 4
5 Corneal Transplantation Guided by OCT RESCAN Unknown status NCT02736877 Not Applicable
6 Comparison of Corneal Grafts Cultured in Serum-free Versus Corneal Grafts Cultured in Serum Supplemented Culture Media Unknown status NCT00623584 Not Applicable
7 Comparing Endoglide to Endoserter for DSAEK Graft Insertion Unknown status NCT01791075 Not Applicable
8 Hyper-CL™ Lens (Hyper Osmotic Contact Lens) In Subjects Suffering From Corneal Edema Unknown status NCT01890252 Not Applicable saline solution
9 Outcome After Descemet Membrane Endothelial Keratoplasty (DMEK) and Ultra-thin Descemet Stripping Automated Endothelial Keratoplasty (DSAEK) Unknown status NCT02020044 Not Applicable
10 Long Term Results of Amniotic Membrane Transplant in Bullous Keratopathy Patients Completed NCT03450954
11 Amniotic Membrane and Anterior Stromal Puncture to the Treatment of Symptomatic Bullous Keratopathy Completed NCT00659308 Not Applicable
12 The Effects of Riboflavin/ Ultraviolet-A Corneal Cross-linking on the Signs and Symptoms of Bullous Keratopathy Completed NCT01106274 Not Applicable
13 Automated Lamellar Keratectomy in Symptomatic Patients With Bullous Keratopathy Completed NCT00654888 Not Applicable Mitomycin
14 The SNEC DSAEK EndoGlide Clinical Trial Completed NCT01122043
15 Study of Using the Hyper-CL™ Lens (Hyper Osmotic Contact Lens) in Subjects Suffering From Corneal Edema Completed NCT02660151 Not Applicable Salt solution
16 Study of Endothelial Keratoplasty Outcomes Completed NCT00800111 Not Applicable
17 Air Versus SF6 for Descemet's Membrane Endothelial Keratoplasty (DMEK) Recruiting NCT03407755 Not Applicable
18 The ADVISE Study: Advanced Visualization In Corneal Surgery Evaluation Recruiting NCT03763721 Not Applicable
19 Topical Steroid Treatment After Posterior Lamellar Corneal Transplantation Withdrawn NCT01682421 Not Applicable Weak steroid (Flurolon, Allergan);Potent steroid (Maxidex, Alcon)

Search NIH Clinical Center for Bullous Keratopathy

Genetic Tests for Bullous Keratopathy

Anatomical Context for Bullous Keratopathy

MalaCards organs/tissues related to Bullous Keratopathy:

42
Endothelial, Eye, Skin, Testes

Publications for Bullous Keratopathy

Articles related to Bullous Keratopathy:

(showing 287, show less)
# Title Authors Year
1
Decreased epithelial to corneal thickness ratio in healthy fellow eyes of patients with unilateral bullous keratopathy. ( 31000511 )
2019
2
Different graft thicknesses after Descemet stripping endothelial keratoplasty for bullous keratopathy in the two eyes of the same patient. ( 30881147 )
2019
3
Triple procedure for pseudophakic bullous keratopathy in complicated cataract surgery: Glued IOL with single-pass four-throw pupilloplasty with pre-Descemet's endothelial keratoplasty. ( 30819560 )
2019
4
Effect of topical steroid instillation on central corneal thickness in eyes with bullous keratopathy. ( 30783940 )
2019
5
Cytokine Levels in the Aqueous Humor Are Associated With Corneal Thickness in Eyes With Bullous Keratopathy. ( 30316668 )
2019
6
Dry eye and meibomian gland dysfunction in pseudophakic bullous keratopathy. ( 29392636 )
2019
7
Cultured Cells and ROCK Inhibitor for Bullous Keratopathy. ( 30260153 )
2018
8
Cultured Cells and ROCK Inhibitor for Bullous Keratopathy. ( 30260152 )
2018
9
Cultured Cells and ROCK Inhibitor for Bullous Keratopathy. ( 30231219 )
2018
10
Sustainability of Pain Relief After Corneal Collagen Cross-Linking in Eyes With Bullous Keratopathy. ( 29993202 )
2018
11
Primary Descemet's Membrane Endothelial Keratoplasty for Fuchs Endothelial Dystrophy versus Bullous Keratopathy: Histopathology and Clinical Results. ( 29939775 )
2018
12
Endothelial cell loss and graft survival after penetrating keratoplasty for laser iridotomy-induced bullous keratopathy. ( 29766356 )
2018
13
Glued intraocular lens with descemet stripping endothelial keratoplasty in aphakic bullous keratopathy. ( 29692490 )
2018
14
Wheel Spokes Technique for Endothelial Keratoplasty for Extremely Mydriatic Bullous Keratopathy Eyes without Capsular Support. ( 29681843 )
2018
15
Bilateral bullous keratopathy secondary to melting keratitis in a Suri alpaca (Vicugna pacos). ( 29636928 )
2018
16
Painless bilateral bullous keratopathy. ( 29573998 )
2018
17
Injection of Cultured Cells with a ROCK Inhibitor for Bullous Keratopathy. ( 29539291 )
2018
18
Primary Bullous Keratopathy in a Patient With Werner Syndrome Treated With Corneal Transplant. ( 29534662 )
2018
19
Human corneal endothelial cell transplantation using nanocomposite gel sheet in bullous keratopathy. ( 29531856 )
2018
20
Topical ganciclovir treatment post-Descemet's stripping automated endothelial keratoplasty for patients with bullous keratopathy induced by cytomegalovirus. ( 29363530 )
2018
21
Pseudophakic bullous keratopathy. ( 29450379 )
2017
22
Regulatory Compliant Tissue-Engineered Human Corneal Endothelial Grafts Restore Corneal Function of Rabbits with Bullous Keratopathy. ( 29074873 )
2017
23
Young donor-graft assisted endothelial keratoplasty (PDEK/DMEK) with epithelial debridement for chronic pseudophakic bullous keratopathy. ( 28985815 )
2017
24
Descemet Stripping Automated Endothelial Keratoplasty in Fuchs' Endothelial Dystrophy versus Pseudophakic Bullous Keratopathy. ( 27994806 )
2016
25
Comparison of Long-term Clinical Outcomes between Descemet's Stripping Automated Endothelial Keratoplasty and Penetrating Keratoplasty in Patients with Bullous Keratopathy. ( 27980363 )
2016
26
Elevated Cytokine Levels in the Aqueous Humor of Eyes With Bullous Keratopathy and Low Endothelial Cell Density. ( 27820951 )
2016
27
Corneal Collagen Cross Linking (CXL) in treatment of Pseudophakic Bullous Keratopathy. ( 27648049 )
2016
28
Superficial Keratectomy and Conjunctival Advancement Hood Flap (SKCAHF) for the Management of Bullous Keratopathy: Validation in Dogs With Spontaneous Disease. ( 27538190 )
2016
29
Non-Descemet Stripping Automated Endothelial Keratoplasty for Bullous Keratopathy in Buphthalmic Eye. ( 27462256 )
2016
30
An association between systemic cyclosporine administration and development of acute bullous keratopathy in cats. ( 26880480 )
2016
31
Corneal Tattooing and Anterior Stromal Puncture for Treating Symptomatic Bullous Keratopathy. ( 26606297 )
2016
32
Changes in Corneal Biomechanical Properties After Descemet Stripping Automated Endothelial Keratoplasty for Pseudophakic Bullous Keratopathy. ( 26555584 )
2016
33
Anterior corneal surface irregularity after Descemet-stripping endothelial keratoplasty for bullous keratopathy. ( 26541104 )
2016
34
Simultaneous Descemet's membrane endothelial keratoplasty and posterior iris-claw-fixated intra ocular lens implantation (IOL) in management of aphakic bullous keratopathy. ( 26286755 )
2016
35
Evaluation of accelerated corneal collagen cross-linking for the treatment of bullous keratopathy in eight dogs (10 eyes). ( 25959108 )
2016
36
Occult Descemet's membrane detachment after phacoemulsification surgery mimicking pseudophakic bullous keratopathy. ( 29018686 )
2015
37
Real-Time Microscope-Integrated OCT to Improve Visualization in DSAEK for Advanced Bullous Keratopathy. ( 26509766 )
2015
38
Effect of Glyceraldehyde Cross-Linking on a Rabbit Bullous Keratopathy Model. ( 26509077 )
2015
39
Recurrent rates and risk factors associated with recurrent painful bullous keratopathy after primary phototherapeutic keratectomy. ( 26491241 )
2015
40
Case series and techniques of Descemet's Stripping Automated Endothelial Keratoplasty for severe bullous keratopathy after birth injury. ( 26245501 )
2015
41
The use of endoillumination probe-assisted Descemet membrane endothelial keratoplasty for bullous keratopathy secondary to argon laser iridotomy. ( 25609910 )
2015
42
Long-term symptomatic relief of bullous keratopathy with amniotic membrane transplant. ( 25586624 )
2015
43
Treatment of bullous keratopathy with corneal collagen cross-linking in two dogs. ( 24373539 )
2015
44
Use of amniotic membrane in bullous keratopathy palliative care. ( 25870682 )
2014
45
Ultrasound biomicroscopy after palliative surgical procedures for bullous keratopathy: a descriptive comparative study. ( 25627186 )
2014
46
Outcome of Two Corneal Collagen Crosslinking Methods in Bullous Keratopathy due to Fuchs' Endothelial Dystrophy. ( 25484904 )
2014
47
Endoilluminator-assisted transcorneal illumination for Descemet membrane endothelial keratoplasty: enhanced intraoperative visualization of the graft in corneal decompensation secondary to pseudophakic bullous keratopathy. ( 25088633 )
2014
48
Re: Arora et al.: Role of corneal collagen cross-linking in pseudophakic bullous keratopathy: a clinicopathological study (Ophthalmology 2013;120:2413-8). ( 25015213 )
2014
49
Three-year outcome of Descemet stripping automated endothelial keratoplasty for bullous keratopathy after argon laser iridotomy. ( 24915015 )
2014
50
Regeneration of corneal endothelial cells following keratoplasty in rats with bullous keratopathy. ( 24883013 )
2014
51
Superficial epithelial keratectomy, cautery, and amniotic membrane transplant for the treatment of painful bullous keratopathy in eyes with poor visual potential. ( 24815111 )
2014
52
Alternatives to corneal transplantation for the management of bullous keratopathy. ( 24807064 )
2014
53
Femtosecond laser-assisted intracorneal biopolymer insertion for the symptomatic treatment of bullous keratopathy. ( 24619170 )
2014
54
Comparison of sulfur hexafluoride and air for donor attachment in Descemet stripping endothelial keratoplasty in patients with pseudophakic bullous keratopathy. ( 24452211 )
2014
55
Outcomes of corneal collagen crosslinking in pseudophakic bullous keratopathy. ( 24452209 )
2014
56
Iridoschisis associated with nanophthalmos and bullous keratopathy. ( 23001742 )
2013
57
Combined scraping, coagulation, and subconjunctival bevacizumab in Descemet stripping automated endothelial keratoplasty for bullous keratopathy. ( 23161181 )
2013
58
Complement activation in the aqueous humor of pseudophakic bullous keratopathy patients. ( 23258303 )
2013
59
Amniotic membrane transplantation versus anterior stromal puncture in bullous keratopathy: a comparative study. ( 23723410 )
2013
60
Autologous tragal perichondrium transplantation: a novel approach for the management of painful bullous keratopathy. ( 23730105 )
2013
61
Comparison of treatments for bullous keratopathy in rabbits. ( 23737903 )
2013
62
Descemet stripping automated endothelial keratoplasty for bullous keratopathy after anterior-posterior radial keratotomy. ( 23770978 )
2013
63
Descemet stripping automated endothelial keratoplasty for bullous keratopathy with an irregular posterior surface. ( 23846407 )
2013
64
Non-Descemet's stripping automated endothelial keratoplasty for bullous keratopathy secondary to iridoschisis. ( 23861578 )
2013
65
Role of corneal collagen cross-linking in pseudophakic bullous keratopathy: a clinicopathological study. ( 23953101 )
2013
66
An atypical case of herpes simplex virus endotheliitis presented as bullous keratopathy. ( 23957427 )
2013
67
Midinfrared Laser Pancorneal Coagulation as a Method of Treatment for Painful Bullous Keratopathy. ( 23974894 )
2013
68
Persistence of structural changes at the anterior cornea in bullous keratopathy patients after endothelial keratoplasty. ( 24066132 )
2013
69
Bullous keratopathy as a progressive disease: evidence from clinical and laboratory imaging studies. ( 24104939 )
2013
70
Endothelial keratoplasty for bullous keratopathy in eyes with an anterior chamber intraocular lens. ( 24286840 )
2013
71
Management of bullous keratopathy-related ulcer with autologous serum. ( 22781466 )
2013
72
'Dirty Picture!-Pleasant outcome' - A two step approach to anterior staphyloma and bullous keratopathy. ( 24600153 )
2013
73
Treatment of symptomatic bullous keratopathy with poor visual prognosis using a modified Gundersen conjunctival flap and amniotic membrane. ( 22956637 )
2012
74
Descemet-stripping automated endothelial keratoplasty for vitrectomized cases with traumatic aniridia and aphakic bullous keratopathy. ( 23055672 )
2012
75
Rationale for performing penetrating keratoplasty rather than DSAEK in patients with bullous keratopathy in Japan. ( 22869384 )
2012
76
Abnormalities of stromal structure in the bullous keratopathy cornea identified by second harmonic generation imaging microscopy. ( 22736613 )
2012
77
In vivo confocal microscopic and histological findings of unknown bullous keratopathy probably associated with pseudoexfoliation syndrome. ( 22727450 )
2012
78
Histological evaluation of corneal scar formation in pseudophakic bullous keratopathy. ( 22720074 )
2012
79
Descemetorrhexis in endothelial keratoplasty to avoid peripheral bullous keratopathy. ( 22687300 )
2012
80
Beauveria bassiana keratitis in bullous keratopathy: antifungal sensitivity testing and management. ( 22467587 )
2012
81
Surgical outcome of Descemet's stripping automated endothelial keratoplasty for bullous keratopathy secondary to argon laser iridotomy. ( 22286710 )
2012
82
Effect of preoperative duration of stromal edema in bullous keratopathy on early visual acuity after endothelial keratoplasty. ( 22153314 )
2012
83
Analysis of causes of bullous keratopathy in East China: a 10-year retrospective study. ( 21221627 )
2012
84
The expression of interleukin-1 alpha, TNF and VEGF in corneal cells of patients with bullous keratopathy. ( 22220428 )
2011
85
Bullous keratopathy. ( 22047894 )
2011
86
Chandelier illumination for use during descemet stripping automated endothelial keratoplasty in patients with advanced bullous keratopathy. ( 21912231 )
2011
87
Immunohistofluorescence analysis of myofibroblast transdifferentiation in human corneas with bullous keratopathy. ( 21866044 )
2011
88
Reproducibility of cornea measurements in anterior segment OCT images of normal eyes and eyes with bullous keratopathy analyzed with the Zhongshan Assessment Program. ( 21828152 )
2011
89
Combined amniotic membrane transplant and anterior stromal puncture in painful bullous keratopathy: clinical outcome and confocal microscopy. ( 21708086 )
2011
90
The effects of riboflavin/ultraviolet: a corneal cross-linking on the signs and symptoms of bullous keratopathy. ( 21572736 )
2011
91
Corneal nerve aberrations in bullous keratopathy. ( 21310389 )
2011
92
UV-riboflavin cross-linking of the cornea in bullous keratopathy: appraising the rationale. ( 21282989 )
2011
93
Huge Bullous Keratopathy following Trauma. ( 22737374 )
2010
94
Collagen crosslinking in pseudophakic bullous keratopathy. ( 20656182 )
2010
95
Combined phototherapeutic keratectomy and amniotic membrane grafts for symptomatic bullous keratopathy. ( 20595900 )
2010
96
A 10.0-mm posterior lamellar graft for bullous keratopathy in a buphthalmic eye. ( 20595891 )
2010
97
Comparative evaluation of phototherapeutic keratectomy and amniotic membrane transplantation for management of symptomatic chronic bullous keratopathy. ( 20517149 )
2010
98
A chandelier-illuminated anterior chamber maintainer for use during descemet stripping automated endothelial keratoplasty in patients with advanced bullous keratopathy. ( 20508515 )
2010
99
Non-Invasive Couching Technique to Treat a Morgagnian Cataract Causing Bullous Keratopathy. ( 20438042 )
2010
100
Collagen crosslinking with riboflavin and ultraviolet-A in eyes with pseudophakic bullous keratopathy. ( 20152609 )
2010
101
Differential expression of transforming growth factor-beta isoforms in bullous keratopathy corneas. ( 20142847 )
2010
102
Prospective comparison of two suturing techniques of amniotic membrane transplantation for symptomatic bullous keratopathy. ( 20103046 )
2010
103
Sutureless amniotic membrane fixation with fibrin glue in symptomatic bullous keratopathy with poor visual potential. ( 20047183 )
2010
104
UV-A Collagen Cross-Linking Treatment of Bullous Keratopathy Combined With Corneal Ulcer. ( 20023590 )
2010
105
Impression cytology findings in bullous keratopathy. ( 19965819 )
2010
106
Superficial keratectomy as a prelude for endothelial keratoplasty in severe bullous keratopathy with anterior stromal scarring. ( 19907302 )
2010
107
Cultivated autologous limbal epithelial transplantation for symptomatic bullous keratopathy. ( 21686396 )
2009
108
Long-term topical steroid treatment after penetrating keratoplasty in patients with pseudophakic bullous keratopathy. ( 19815284 )
2009
109
Combined phototherapeutic keratectomy and amniotic membrane grafts for symptomatic bullous keratopathy. ( 19724207 )
2009
110
Corneal collagen cross-linking in bullous keratopathy. ( 19714792 )
2009
111
Argon laser iridotomy-induced bullous keratopathy. ( 19471010 )
2009
112
Exfoliative epitheliopathy of bullous keratopathy with breaches in the MUC16 Glycocalyx. ( 19420336 )
2009
113
Complex deep lamellar endothelial keratoplasty for complex bullous keratopathy with severe vision loss. ( 19158557 )
2009
114
Potential use of riboflavin/UVA cross-linking in bullous keratopathy. ( 19122475 )
2009
115
Prospective comparison of two suturing techniques of amniotic membrane transplantation for symptomatic bullous keratopathy. ( 19019342 )
2009
116
Penetrating keratoplasty for bullous keratopathy after trabeculectomy. ( 18369373 )
2009
117
The expression of human corneal MMP-2, MMP-9, proMMP-13 and TIMP-1 in bullous keratopathy and keratoconus. ( 19138000 )
2008
118
Localized bullous keratopathy secondary to posterior polymorphous dystrophy. ( 19128391 )
2008
119
Sutureless amniotic membrane fixation with fibrin glue in symptomatic bullous keratopathy with poor visual potential. ( 18988175 )
2008
120
Management of pseudophakic bullous keratopathy by combined Descemet-stripping endothelial keratoplasty and intraocular lens exchange. ( 18812122 )
2008
121
Simultaneous phacoemulsification and DSEK in patients with concomitant cataract and bullous keratopathy due to Fuchs endothelial dystrophy. ( 18812092 )
2008
122
Staged intrastromal delivery of riboflavin with UVA cross-linking in advanced bullous keratopathy: laboratory investigation and first clinical case. ( 18811120 )
2008
123
Management of angle-closure glaucoma in East Asian eyes: a response to argon laser iridotomy-induced bullous keratopathy, a growing problem in Japan. ( 18723753 )
2008
124
Posterior mushroom keratoplasty in patients with Fuchs endothelial dystrophy and pseudophakic bullous keratopathy: transplant outcome. ( 18580259 )
2008
125
P53, CD95, cathepsin and survivin pathways in Fuchs' dystrophy and pseudophakic bullous keratopathy corneas. ( 18498065 )
2008
126
Cryopreserved amniotic membrane transplantation for the management of symptomatic bullous keratopathy. ( 18352868 )
2008
127
Acute bullous keratopathy in a domestic shorthair. ( 18309751 )
2008
128
Argon laser iridotomy-induced bullous keratopathy a growing problem in Japan. ( 17567658 )
2007
129
Laminins in normal, keratoconus, bullous keratopathy and scarred human corneas. ( 17492460 )
2007
130
National survey on bullous keratopathy in Japan. ( 17413952 )
2007
131
Ultrasound biomicroscopy study of the Verisyse aphakic intraocular lens combined with penetrating keratoplasty in pseudophakic bullous keratopathy. ( 17321397 )
2007
132
Amniotic membrane transplantation for painful bullous keratopathy. ( 17294377 )
2007
133
Amniotic membrane transplantation with anterior stromal micropuncture for treatment of painful bullous keratopathy in eyes with poor visual potential. ( 17251820 )
2007
134
Towards cell therapeutics for bullous keratopathy using corneal endothelial precursor cells; successful in vitro expansion after transportation in Indian conditions and characterization. ( 24692864 )
2006
135
AC/PC Intraocular Lens Exchange with Penetrating Keratoplasty in Pseudophakic Bullous Keratopathy. ( 27407833 )
2006
136
Therapeutic efficacy of 5% NaCl hypertonic solution in patients with bullous keratopathy. ( 16848159 )
2006
137
Long-standing bullous keratopathy is associated with peripheral conjunctivalization and limbal deficiency. ( 16647124 )
2006
138
A novel application of amniotic membrane in patients with bullous keratopathy. ( 16614522 )
2006
139
Pseudophakic bullous keratopathy in a case of corneal birth trauma. ( 16498437 )
2006
140
Efficacy of two chondroitin sulfate ophthalmic solutions in the therapy of spontaneous chronic corneal epithelial defects and ulcerative keratitis associated with bullous keratopathy in dogs. ( 16497231 )
2006
141
Epithelial cell, keratocyte, and endothelial cell apoptosis in Fuchs dystrophy and in pseudophakic bullous keratopathy. ( 28221424 )
2005
142
The results of amniotic membrane transplantation for symptomatic bullous keratopathy. ( 16681053 )
2005
143
Treatment of rabbit bullous keratopathy with precursors derived from cultured human corneal endothelium. ( 16186344 )
2005
144
Post-LASIK corneal flap displacement following penetrating keratoplasty for bullous keratopathy. ( 16160509 )
2005
145
Bullous keratopathy and corneal decompensation secondary to iridoschisis: a clinicopathological report. ( 16160507 )
2005
146
Bullous keratopathy as a complication of trabeculectomy with mitomycin C. ( 15940484 )
2005
147
Bullous keratopathy treated with honey. ( 15799749 )
2005
148
A morphologic study of Fuchs dystrophy and bullous keratopathy. ( 15778606 )
2005
149
Epithelial cell, keratocyte, and endothelial cell apoptosis in Fuchs' dystrophy and in pseudophakic bullous keratopathy. ( 15751234 )
2005
150
Altered expression of aquaporins in bullous keratopathy and Fuchs' dystrophy corneas. ( 15385580 )
2004
151
Bullous keratopathy treated with honey. ( 15115455 )
2004
152
Penetrating keratoplasty and Artisan iris-fixated intraocular lens implantation in the management of aphakic bullous keratopathy. ( 15084853 )
2004
153
Recurrence of giant pseudocyst in advanced bullous keratopathy. ( 14976545 )
2004
154
Dislocation of a scleral-fixated posterior chamber intraocular lens into the anterior chamber associated with pseudophakic bullous keratopathy. ( 14750768 )
2004
155
Long-term follow-up for bullous keratopathy after sato-type anterior-posterior corneal refractive surgery. ( 14644229 )
2003
156
Response to symptomatic management of postoperative bullous keratopathy with nonpreserved human amniotic membrane. ( 12605061 )
2003
157
Use of thermokeratoplasty for treatment of ulcerative keratitis and bullous keratopathy secondary to corneal endothelial disease in dogs: 13 cases (1994-2001). ( 12619840 )
2003
158
Amniotic membrane transplantation for bullous keratopathy in eyes with poor visual potential. ( 12648638 )
2003
159
Visual acuity after penetrating keratoplasty for pseudophakic and aphakic bullous keratopathy. ( 12663010 )
2003
160
Anterior stromal puncture for bullous keratopathy. ( 14509459 )
2003
161
Insulin-like growth factor-I (IGF-I) and transforming growth factor-beta (TGF-beta) modulate tenascin-C and fibrillin-1 in bullous keratopathy stromal cells in vitro. ( 14550395 )
2003
162
Bullous keratopathy after argon laser iridotomy presumably associated with latanoprost. ( 14636857 )
2003
163
Extracellular matrix and Na+,K+-ATPase in human corneas following cataract surgery: comparison with bullous keratopathy and Fuchs' dystrophy corneas. ( 11805512 )
2002
164
Symptomatic management of postoperative bullous keratopathy with nonpreserved human amniotic membrane. ( 11973379 )
2002
165
Histology of microcornea complicated by bullous keratopathy. ( 11167300 )
2001
166
Ultrastructural morphology and expression of proteoglycans, betaig-h3, tenascin-C, fibrillin-1, and fibronectin in bullous keratopathy. ( 11371495 )
2001
167
Altered expression of growth factors and cytokines in keratoconus, bullous keratopathy and diabetic human corneas. ( 11446768 )
2001
168
Combined phototherapeutic keratectomy and therapeutic contact lens for recurrent erosions in bullous keratopathy. ( 11466242 )
2001
169
A comparison of different depth ablations in the treatment of painful bullous keratopathy with phototherapeutic keratectomy. ( 11466243 )
2001
170
Herpes simplex virus bullous keratitis misdiagnosed as a case of pseudophakic bullous keratopathy with secondary glaucoma: an unusual presentation. ( 11472638 )
2001
171
Anterior stromal puncture in the treatment of bullous keratopathy: six-month follow-up. ( 11473154 )
2001
172
Anterior stromal puncture in bullous keratopathy: a clinicopathologic study. ( 11473155 )
2001
173
Increased expression of tenascin-C-binding epithelial integrins in human bullous keratopathy corneas. ( 11668187 )
2001
174
Ophthaproblem. Pseudophakic bullous keratopathy. ( 10907565 )
2000
175
Phakic-pseudophakic bullous keratopathy following implantation of a posterior chamber IOL in the anterior chamber to correct hypermetropia. ( 11217259 )
2000
176
Posterior lamellar keratoplasty for a case of pseudophakic bullous keratopathy. ( 10088746 )
1999
177
Surgical management of coexisting pseudophakic bullous keratopathy and glaucoma. ( 10511928 )
1999
178
Amniotic membrane transplantation for symptomatic bullous keratopathy. ( 10532436 )
1999
179
Analysis of gene expression in human bullous keratopathy corneas containing limiting amounts of RNA. ( 10586931 )
1999
180
Management of coexisting pseudophakic bullous keratopathy and open-angle glaucoma. ( 9493117 )
1998
181
Increased expression of fibrillin-1 in human corneas with bullous keratopathy. ( 9603388 )
1998
182
Novel splice variants of human tenascin-C mRNA identified in normal and bullous keratopathy corneas. ( 9603390 )
1998
183
Expression of tenascin-C splice variants in normal and bullous keratopathy human corneas. ( 9620072 )
1998
184
Tenascin-cytotactin (TN-C) variants in pseudophakic/aphakic bullous keratopathy corneas. ( 9850274 )
1998
185
Ulcerative keratitis in bullous keratopathy. ( 9160028 )
1997
186
Penetrating keratoplasty for pseudophakic bullous keratopathy. ( 9408269 )
1997
187
Annular keratotomy for the treatment of painful bullous keratopathy. ( 8554087 )
1996
188
Extracellular matrix alterations in human corneas with bullous keratopathy. ( 8631643 )
1996
189
Anterior stromal punctures for bullous keratopathy. ( 8639074 )
1996
190
Successful phototherapeutic keratectomy for recurrent erosions in bullous keratopathy. ( 8653513 )
1996
191
Irreversible bullous keratopathy after air bag trauma. ( 8728625 )
1996
192
Adhesion molecule expression in bullous keratopathy. ( 8871168 )
1996
193
Detection of mRNA for the cytokines, interleukin-1 alpha and interleukin-8, in corneas from patients with pseudophakic bullous keratopathy. ( 7657553 )
1995
194
Phototherapeutic keratectomy for bullous keratopathy. ( 7742278 )
1995
195
Penetrating keratoplasty for pseudophakic bullous keratopathy. ( 7927635 )
1994
196
Pseudophakic bullous keratopathy and intraocular lens fixation. To suture or not: that is the question! ( 7945030 )
1994
197
Deep lamellar keratoplasty in the treatment of bullous keratopathy. ( 8025058 )
1993
198
Histopathological study of pseudophakic bullous keratopathy developing after anterior chamber of iris-supported intraocular lens implantation. ( 8145386 )
1993
199
Intentional retention of Descemet's membrane in keratoplasty for the surgical treatment of bullous keratopathy. ( 8333280 )
1993
200
Corneal edema and bullous keratopathy. ( 1469737 )
1992
201
Soemmering's ring support for posterior chamber intraocular lens implantation during penetrating keratoplasty. Changing trends in bullous keratopathy. ( 1513575 )
1992
202
Implantation of Kelman-style, open-loop anterior chamber lenses during keratoplasty for aphakic and pseudophakic bullous keratopathy. A comparison with iris-sutured posterior chamber lenses. ( 1866140 )
1991
203
Pseudophakic bullous keratopathy. ( 1911515 )
1991
204
Proteoglycan distribution in the corneas of individuals with bullous keratopathy. ( 2083765 )
1990
205
Bullous keratopathy due to nonguttate corneal endothelial dystrophy. ( 2261183 )
1990
206
Fellow eyes in aphakic and pseudophakic bullous keratopathy. ( 2299582 )
1990
207
Penetrating keratoplasty for pseudophakic bullous keratopathy associated with closed-loop anterior chamber intraocular lenses. ( 2326019 )
1990
208
Abnormal extracellular matrix in corneas with pseudophakic bullous keratopathy. ( 2328580 )
1990
209
Natural history of cystoid macular edema in pseudophakic bullous keratopathy. ( 2329472 )
1990
210
A prospective study on the implantation of anterior chamber intraocular lenses during keratoplasty for pseudophakic and aphakic bullous keratopathy. ( 2374680 )
1990
211
An analysis of corneal endothelial and graft survival in pseudophakic bullous keratopathy. ( 2562532 )
1989
212
The bandage lens in bullous keratopathy. ( 2594381 )
1989
213
Penetrating keratoplasty for pseudophakic bullous keratopathy associated with semiflexible, closed-loop anterior chamber intraocular lenses. ( 2646933 )
1989
214
Management of pseudophakic bullous keratopathy. ( 2652024 )
1989
215
Penetrating keratoplasty and intraocular lens exchange for pseudophakic bullous keratopathy associated with a closed-loop anterior chamber intraocular lens. ( 2665503 )
1989
216
The dilemma of pseudophakic bullous keratopathy. ( 2674810 )
1989
217
Pseudophakic bullous keratopathy in Switzerland. ( 2776944 )
1989
218
Results of penetrating keratoplasty for pseudophakic bullous keratopathy with the exchange of an intraocular lens. ( 2804025 )
1989
219
Propionibacterium acnes isolated from explanted intraocular lens in pseudophakic bullous keratopathy. ( 2805713 )
1989
220
Pseudophakic bullous keratopathy. ( 3048108 )
1988
221
Penetrating keratoplasty for pseudophakic bullous keratopathy. Management of the intraocular lens. ( 3062537 )
1988
222
Pseudophakic bullous keratopathy with Intermedics model 024 (Hessburg) anterior chamber intraocular lenses. ( 3190544 )
1988
223
A comparison of corneal endothelial morphology in cornea guttata, Fuchs' dystrophy and bullous keratopathy. ( 3263136 )
1988
224
The incidence of preoperative endothelial dystrophy in pseudophakic bullous keratopathy. ( 3277104 )
1988
225
Penetrating keratoplasty for pseudophakic bullous keratopathy after extracapsular cataract extraction. ( 3282436 )
1988
226
Bullous keratopathy: a study of endothelial cell morphology in patients undergoing cataract surgery. ( 3390413 )
1988
227
Cytochrome oxidase activity of postsurgical bullous keratopathy endothelium. ( 2822357 )
1987
228
Intraocular lens removal during penetrating keratoplasty for pseudophakic bullous keratopathy. ( 3299201 )
1987
229
Intraocular lens removal during penetrating keratoplasty for pseudophakic bullous keratopathy. ( 3323988 )
1987
230
Epikeratophakia for control of pediatric bullous keratopathy. ( 3559955 )
1987
231
Use of posterior chamber lenses in pseudophakic bullous keratopathy. ( 3579717 )
1987
232
Penetrating keratoplasty in aphakic and pseudophakic bullous keratopathy. ( 2980828 )
1986
233
Results of penetrating keratoplasty for aphakic bullous keratopathy. ( 3155046 )
1986
234
Penetrating keratoplasty in aphakic bullous keratopathy. ( 3155047 )
1986
235
Fellow eyes of aphakic bullous keratopathy (a specular microscopic study). ( 3155048 )
1986
236
Localized bullous keratopathy secondary to adherent lens capsule. ( 3707407 )
1986
237
Pseudophakic bullous keratopathy: relationship with endothelial cell density and use of a predictive cell loss model. A preliminary report. ( 3720342 )
1986
238
Visual acuity, refractive error, and astigmatism following corneal transplantation for pseudophakic bullous keratopathy. ( 3909036 )
1985
239
Endothelial wound-healing in penetrating corneal graft for experimental bullous keratopathy in rabbit. ( 2421030 )
1985
240
Specular microscopic follow-up of corneal grafts for pseudophakic bullous keratopathy. ( 3887265 )
1985
241
Intraocular lens replacement in pseudophakic bullous keratopathy. ( 3901432 )
1985
242
Painful bullous keratopathy following pediatric cataract surgery with intraocular lens implantation. ( 4022557 )
1985
243
Pseudophakic bullous keratopathy. ( 4056286 )
1985
244
Endothelial line associated with pseudophakic bullous keratopathy. ( 4092478 )
1985
245
Aqueous humor cytology of pseudophakic bullous keratopathy. ( 6384163 )
1984
246
Results of penetrating keratoplasty for aphakic and pseudophakic bullous keratopathy. ( 6476053 )
1984
247
Bullous keratopathy: a perspective on the American experience. ( 6478579 )
1984
248
Pseudophakic bullous keratopathy. Relationship to preoperative corneal endothelial status. ( 6514281 )
1984
249
The fellow eye of patients with aphakic bullous keratopathy. ( 6571490 )
1984
250
What's your impression? Dislocated (cataractous) lens with bullous keratopathy. ( 6608004 )
1984
251
Pseudophakic bullous keratopathy. ( 6338434 )
1983
252
Iridoschisis associated with glaucoma and bullous keratopathy. ( 6849370 )
1983
253
Bullous keratopathy after anterior-posterior radial keratotomy for myopia for myopic astigmatism. ( 7081358 )
1982
254
The ultrastructure of Descemet's membrane. II. Aphakic bullous keratopathy. ( 7150062 )
1982
255
Penetrating keratoplasty for pseudophakic bullous keratopathy. Visual results. ( 7011282 )
1981
256
Visual prognosis in aphakic bullous keratopathy treated by penetrating keratoplasty: a retrospective study of 73 cases. ( 7015213 )
1981
257
Aphakic bullous keratopathy: preoperative fluorescein angiographic screening for macular edema. ( 7023826 )
1981
258
Bullous keratopathy accompanying essential iris atrophy: response to lowered intraocular pressure. ( 6927215 )
1980
259
Penetrating keratoplasty in pseudophakic bullous keratopathy. ( 7004193 )
1980
260
Pseudophakic bullous keratopathy. A clinical-pathologic analysis. ( 311238 )
1979
261
Keratoplasty in Fuchs' dystrophy and bullous keratopathy. ( 384801 )
1979
262
Visual results after penetrating keratoplasty for aphakic bullous keratopathy and Fuchs' dystrophy. ( 391046 )
1979
263
Endothelial degeneration and posterior collagenous proliferation in aphakic bullous keratopathy. ( 306751 )
1978
264
Keratoplasty for bullous keratopathy with intraocular lens. ( 359527 )
1978
265
Bullous keratopathy (Fuchs' endothelial dystrophy) treated systemically with 4-trans-amino-cyclohexano-carboxylic acid. ( 302548 )
1977
266
Bullous keratopathy following lens extraction in eyes with acute glaucoma due to intumescent cataract. ( 958674 )
1976
267
Aphakic bullous keratopathy treated with prosthokeratoplasty. An analysis of 34 consecutive cases. ( 1252179 )
1976
268
Soft contact lens treatment of bullous keratopathy. ( 1064214 )
1975
269
Incidence of bullous keratopathy. ( 1230273 )
1975
270
Bullous keratopathy: a latent complication of chronic corneal disease. ( 4492813 )
1974
271
Some aspects of bullous keratopathy in aphakia. ( 4804951 )
1973
272
Histopathologic findings in corneas following lens extraction and results of keratoplasty for aphakic bullous keratopathy. ( 4940981 )
1971
273
Hydrophilic contact lenses in corneal disease. 3. Topical hypertonic saline therapy in bullous keratopathy. ( 5315226 )
1971
274
Hydrophilic contact lenses in corneal disease. II. Bullous keratopathy. ( 5542864 )
1971
275
Bandage lenses in the treatment of bullous keratopathy. ( 5571221 )
1971
276
A technique of keratoplasty for aphakic bullous keratopathy. ( 4989801 )
1969
277
The synthesis of basement membrane by the corneal epithelium in bullous keratopathy. ( 5305049 )
1969
278
Penetrating corneal transplants for aphakic bullous keratopathy. ( 4875497 )
1968
279
Surgical relief of bullous keratopathy. (Gunderson's operation). ( 5227192 )
1965
280
INFERIOR BULLOUS KERATOPATHY AND UNSUSPECTED ANTERIOR CHAMBER FOREIGN BODY. ( 14318494 )
1965
281
THE USE OF GUNDERSEN FLAPS IN THE TREATMENT OF BULLOUS KERATOPATHY. ( 14167225 )
1964
282
HYPER-REGENERATION OF CORNEAL NERVES IN BULLOUS KERATOPATHY. ( 14177977 )
1964
283
Surgical treatment of bullous keratopathy. ( 13884810 )
1961
284
Surgical treatment of bullous keratopathy. ( 13830287 )
1960
285
Clinical observations on the treatment of bullous keratopathy. ( 13556833 )
1957
286
The role of the endothelium in bullous keratopathy. ( 13361609 )
1956
287
Studies on the clinical physiology of the cornea; the interrelationship of corneal turgescence, epithelial edema, bullous keratopathy, and interstitial vascularization. ( 18121090 )
1949

Variations for Bullous Keratopathy

Expression for Bullous Keratopathy

Search GEO for disease gene expression data for Bullous Keratopathy.

Pathways for Bullous Keratopathy

Pathways related to Bullous Keratopathy according to GeneCards Suite gene sharing:

(showing 27, show less)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.63 BMP2 BMP4 CXCL8 FBN1 IL1A TGFB2
2
Show member pathways
13.09 BMP2 BMP4 CXCL8 IL1A TGFB2
3
Show member pathways
12.81 BMP2 BMP4 FBN1 TGFB2 TNC
4 12.63 BMP2 BMP4 CXCL8 TGFB2
5
Show member pathways
12.47 BMP2 BMP4 IL1A TGFB2
6
Show member pathways
12.09 BMP2 BMP4 FBN1 NID1 TGFB2 TNC
7
Show member pathways
12.03 CXCL8 FBN1 IL1A TNC
8 11.96 CXCL8 IL1A TGFB2
9 11.93 BMP2 BMP4 TGFB2
10
Show member pathways
11.93 BMP2 BMP4 CXCL8 IL1A TGFB2
11 11.88 BMP4 IL1A SELE
12 11.86 BMP2 BMP4 TGFB2
13
Show member pathways
11.78 BMP2 BMP4 CXCL8 IL1A TGFB2
14 11.74 BMP2 CXCL8 IL1A
15 11.65 CXCL8 IL1A TGFB2
16 11.64 BMP2 BMP4 TGFB2
17 11.56 CXCL8 IL1A SELE TGFB2
18 11.5 BMP2 BMP4 TGFB2
19
Show member pathways
11.45 CXCL8 IL1A SELE
20 11.37 CXCL8 SELE TGFB2
21
Show member pathways
11.32 BMP2 BMP4 FBN1 TGFB2
22 11.3 CXCL8 SELE TGFB2
23 11.22 SELE TNC
24 11.01 BMP2 BMP4
25 10.94 BMP2 BMP4 CXCL8 IL1A
26 10.93 BMP2 BMP4
27 10.07 BMP2 BMP4 CXCL8 FBN1 IL1A TGFB2

GO Terms for Bullous Keratopathy

Cellular components related to Bullous Keratopathy according to GeneCards Suite gene sharing:

(showing 4, show less)
# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.56 BMP2 BMP4 CXCL8 FBN1 IL1A NID1
2 collagen-containing extracellular matrix GO:0062023 9.46 FBN1 NID1 TGFB2 TNC
3 basement membrane GO:0005604 9.43 FBN1 NID1 TNC
4 extracellular space GO:0005615 9.23 BMP2 BMP4 CXCL8 FBN1 IL1A SELE

Biological processes related to Bullous Keratopathy according to GeneCards Suite gene sharing:

(showing 46, show less)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 9.94 BMP2 BMP4 IL1A TNC
2 inflammatory response GO:0006954 9.92 BMP2 CXCL8 IL1A SELE
3 negative regulation of gene expression GO:0010629 9.87 BMP2 BMP4 TGFB2
4 angiogenesis GO:0001525 9.86 BMP4 CXCL8 TGFB2
5 cellular protein metabolic process GO:0044267 9.85 BMP4 FBN1 TNC
6 extracellular matrix organization GO:0030198 9.85 FBN1 NID1 TNC
7 heart development GO:0007507 9.85 BMP2 BMP4 FBN1 TGFB2
8 negative regulation of cell proliferation GO:0008285 9.8 BMP2 BMP4 CXCL8 IL1A TGFB2
9 kidney development GO:0001822 9.79 BMP4 FBN1 TGFB2
10 osteoblast differentiation GO:0001649 9.77 BMP2 BMP4 TNC
11 cell development GO:0048468 9.71 BMP2 BMP4 TGFB2
12 branching involved in ureteric bud morphogenesis GO:0001658 9.7 BMP2 BMP4
13 regulation of MAPK cascade GO:0043408 9.7 BMP2 BMP4 TGFB2
14 chondrocyte differentiation GO:0002062 9.69 BMP2 BMP4
15 positive regulation of protein secretion GO:0050714 9.69 IL1A TGFB2
16 SMAD protein signal transduction GO:0060395 9.69 BMP2 BMP4 TGFB2
17 epithelial to mesenchymal transition GO:0001837 9.68 BMP2 TGFB2
18 cellular response to BMP stimulus GO:0071773 9.68 BMP2 BMP4
19 metanephros development GO:0001656 9.68 BMP4 FBN1
20 positive regulation of bone mineralization GO:0030501 9.67 BMP2 BMP4
21 telencephalon development GO:0021537 9.67 BMP2 BMP4
22 odontogenesis of dentin-containing tooth GO:0042475 9.67 BMP2 BMP4 TNC
23 outflow tract septum morphogenesis GO:0003148 9.66 BMP4 TGFB2
24 cardiac muscle cell differentiation GO:0055007 9.66 BMP2 BMP4
25 water transport GO:0006833 9.65 AQP3 MIP
26 embryonic digestive tract development GO:0048566 9.65 CXCL8 TGFB2
27 endocardial cushion morphogenesis GO:0003203 9.65 BMP2 TGFB2
28 positive regulation of pathway-restricted SMAD protein phosphorylation GO:0010862 9.65 BMP2 BMP4 TGFB2
29 positive regulation of cartilage development GO:0061036 9.64 BMP2 BMP4
30 cardiac right ventricle morphogenesis GO:0003215 9.63 BMP4 TGFB2
31 pulmonary valve morphogenesis GO:0003184 9.63 BMP4 TGFB2
32 positive regulation of epithelial to mesenchymal transition GO:0010718 9.63 BMP2 BMP4 TGFB2
33 skeletal system development GO:0001501 9.62 BMP2 BMP4 FBN1 TGFB2
34 cardiac epithelial to mesenchymal transition GO:0060317 9.61 BMP2 TGFB2
35 pathway-restricted SMAD protein phosphorylation GO:0060389 9.61 BMP2 TGFB2
36 atrioventricular valve morphogenesis GO:0003181 9.6 BMP2 TGFB2
37 membranous septum morphogenesis GO:0003149 9.58 BMP4 TGFB2
38 pharyngeal arch artery morphogenesis GO:0061626 9.58 BMP4 TGFB2
39 telencephalon regionalization GO:0021978 9.57 BMP2 BMP4
40 regulation of odontogenesis of dentin-containing tooth GO:0042487 9.56 BMP2 BMP4
41 odontogenesis GO:0042476 9.54 AQP3 BMP4 TGFB2
42 mesenchymal cell proliferation involved in ureteric bud development GO:0072138 9.43 BMP2 BMP4
43 positive regulation of pri-miRNA transcription by RNA polymerase II GO:1902895 9.33 BMP2 BMP4 TGFB2
44 BMP signaling pathway involved in heart induction GO:0003130 9.26 BMP2 BMP4
45 positive regulation of ossification GO:0045778 9.13 BMP2 BMP4 TGFB2
46 regulation of signaling receptor activity GO:0010469 9.1 BMP2 BMP4 CXCL8 FBN1 IL1A TGFB2

Molecular functions related to Bullous Keratopathy according to GeneCards Suite gene sharing:

(showing 8, show less)
# Name GO ID Score Top Affiliating Genes
1 growth factor activity GO:0008083 9.58 BMP2 BMP4 TGFB2
2 extracellular matrix structural constituent GO:0005201 9.5 FBN1 NID1 TNC
3 channel activity GO:0015267 9.43 AQP3 MIP
4 water channel activity GO:0015250 9.37 AQP3 MIP
5 co-receptor binding GO:0039706 9.26 BMP2 BMP4
6 BMP receptor binding GO:0070700 9.16 BMP2 BMP4
7 transforming growth factor beta receptor binding GO:0005160 9.13 BMP2 BMP4 TGFB2
8 cytokine activity GO:0005125 9.02 BMP2 BMP4 CXCL8 IL1A TGFB2

Sources for Bullous Keratopathy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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