Aliases & Classifications for Burns

Summaries for Burns

MedlinePlus : 44 A burn is damage to your body's tissues caused by heat, chemicals, electricity, sunlight, or radiation. Scalds from hot liquids and steam, building fires and flammable liquids and gases are the most common causes of burns. Another kind is an inhalation injury, caused by breathing smoke. There are three types of burns: First-degree burns damage only the outer layer of skin Second-degree burns damage the outer layer and the layer underneath Third-degree burns damage or destroy the deepest layer of skin and tissues underneath Burns can cause swelling, blistering, scarring and, in serious cases, shock, and even death. They also can lead to infections because they damage your skin's protective barrier. Treatment for burns depends on the cause of the burn, how deep it is, and how much of the body it covers. Antibiotic creams can prevent or treat infections. For more serious burns, treatment may be needed to clean the wound, replace the skin, and make sure the patient has enough fluids and nutrition. NIH: National Institute of General Medical Sciences

MalaCards based summary : Burns, also known as burn, is related to complex regional pain syndrome and irritant dermatitis. An important gene associated with Burns is TTR (Transthyretin), and among its related pathways/superpathways are MAPK signaling pathway and T cell receptor signaling pathway. The drugs Tranexamic Acid and Amikacin have been mentioned in the context of this disorder. Affiliated tissues include Umbilical Cord, skin and eye, and related phenotypes are Increased cell death in breast cancer cell lines (MCF10A, MDA-MB-435) and cardiovascular system

Related Diseases for Burns

Diseases related to Burns via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 863)
# Related Disease Score Top Affiliating Genes
1 complex regional pain syndrome 32.1 IL1B TNF
2 irritant dermatitis 32.0 IL1B TNF
3 glossitis 31.8 IL1B TNF TTR
4 vulvar vestibulitis syndrome 31.5 IL1B TNF
5 carpal tunnel syndrome 31.4 IL1B INS TTR
6 pyelonephritis 31.1 ALB IL1B TNF
7 peripheral nervous system disease 31.0 ALB INS TNF TTR
8 compartment syndrome 30.6 ALB TNF
9 toxic shock syndrome 30.5 IL1B SERPINC1 TNF
10 chronic ulcer of skin 30.3 ALB TTR
11 bacterial infectious disease 30.1 CSF2 IL1B TNF
12 decubitus ulcer 30.1 ALB TTR
13 respiratory failure 30.0 ALB TNF TTR
14 fournier gangrene 30.0 ALB SERPINC1
15 critical limb ischemia 29.9 HGF TNF
16 analbuminemia 29.9 ALB TTR
17 staphylococcal toxic shock syndrome 29.8 IL1B TNF
18 lung disease 29.7 CSF2 IL1B TNF
19 trichosporonosis 29.7 CSF2 TNF
20 kwashiorkor 29.6 ALB TTR
21 haemophilus influenzae 29.6 IL1B TNF
22 thyroid crisis 29.6 ALB TTR
23 meningitis 29.5 ALB IL1B TNF
24 stomatitis 29.5 CSF2 IL1B TNF
25 euthyroid sick syndrome 29.5 ALB IL1B
26 duodenal ulcer 29.4 IL1B INS TNF
27 acute kidney tubular necrosis 29.4 ALB HGF
28 protein-energy malnutrition 29.3 ALB TNF TTR
29 arthritis 29.3 CSF2 IL1B TNF
30 endocarditis 29.3 ALB SERPINC1 TNF
31 diabetes mellitus 29.3 ALB IL1B INS TNF
32 acute liver failure 29.3 ALB HGF
33 fatty liver disease 29.3 IL1B INS TNF
34 aphthous stomatitis 29.3 IL1B TNF
35 nonalcoholic steatohepatitis 29.2 INS TNF
36 appendicitis 29.2 ALB IL1B TNF
37 pulmonary fibrosis, idiopathic 29.1 HGF IL1B TNF
38 aplastic anemia 29.1 ALB CSF2 TNF
39 acquired immunodeficiency syndrome 29.1 ALB CSF2 IL1B TNF
40 chronic fatigue syndrome 29.1 CRH IL1B TNF
41 autonomic nervous system disease 29.0 ALB INS TTR
42 sleep apnea 28.9 IL1B INS TNF
43 autoimmune disease 28.9 IL1B INS TNF
44 liver disease 28.8 ALB HGF INS TNF
45 myocardial infarction 28.5 ALB IL1B INS SERPINC1 TNF
46 arteries, anomalies of 28.2 ALB IL1B INS SERPINC1 TNF
47 heart disease 28.2 ALB IL1B INS SERPINC1 TNF
48 gastrointestinal system disease 27.9 ALB CRH IL1B INS TNF
49 burning mouth syndrome 12.6
50 burn-mckeown syndrome 12.6

Graphical network of the top 20 diseases related to Burns:



Diseases related to Burns

Symptoms & Phenotypes for Burns

GenomeRNAi Phenotypes related to Burns according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased cell death in breast cancer cell lines (MCF10A, MDA-MB-435) GR00104-A-0 8.8 CSF2 INS TNF

MGI Mouse Phenotypes related to Burns:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.91 CSF2 HGF IL1B INS SERPINC1 TNF
2 hematopoietic system MP:0005397 9.87 CRH CSF2 HGF IL1B INS SERPINC1
3 homeostasis/metabolism MP:0005376 9.86 ALB CRH CSF2 IL1B INS SERPINC1
4 liver/biliary system MP:0005370 9.63 ALB CRH HGF INS SERPINC1 TNF
5 no phenotypic analysis MP:0003012 9.35 CRH HGF INS TNF TTR
6 renal/urinary system MP:0005367 9.1 ALB CRH CSF2 INS SERPINC1 TTR

Drugs & Therapeutics for Burns

Drugs for Burns (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 1058)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Tranexamic Acid Approved Phase 4,Phase 3,Phase 2,Not Applicable 1197-18-8 5526
2
Amikacin Approved, Investigational, Vet_approved Phase 4,Not Applicable 37517-28-5 37768
3 silver nitrate Approved, Investigational Phase 4,Phase 3,Phase 2
4
Hydrocortisone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 50-23-7 5754
5
Hydrocortisone acetate Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 50-03-3
6
Bronopol Approved Phase 4,Phase 3,Phase 2 52-51-7
7 Parthenolide Approved, Investigational Phase 4,Phase 3 20554-84-1
8
Bacitracin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 1405-87-4 439542 10909430
9
Carboprost tromethamine Approved Phase 4 58551-69-2 5284525 35023177
10
Dexmedetomidine Approved, Vet_approved Phase 4,Phase 2,Phase 1 113775-47-6 68602 5311068
11
Lidocaine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable 137-58-6 3676
12
Epinephrine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable 51-43-4 5816
13
Racepinephrine Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable 329-65-7 838
14
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 437-38-7 3345
15
Tocopherol Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 1406-66-2 14986
16
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1 22916-47-8 4189
17
Chlorhexidine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 55-56-1 2713 9552079
18
Fluticasone Approved, Experimental Phase 4,Phase 3,Phase 2 90566-53-3 62924
19
Benzoyl peroxide Approved Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 94-36-0 7187
20
Clindamycin Approved, Vet_approved Phase 4,Phase 3,Phase 2 18323-44-9 29029
21
Aminolevulinic acid Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 106-60-5 137
22
Angiotensin II Approved, Investigational Phase 4,Phase 2,Phase 3 68521-88-0, 11128-99-7, 4474-91-3 172198 65143
23
Donepezil Approved Phase 4,Phase 3 120014-06-4 3152
24
Remifentanil Approved Phase 4,Not Applicable 132875-61-7 60815
25
Midazolam Approved, Illicit Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 59467-70-8 4192
26
Chlorthalidone Approved Phase 4 77-36-1 2732
27
Aspirin Approved, Vet_approved Phase 4,Phase 3 50-78-2 2244
28
Hydrochlorothiazide Approved, Vet_approved Phase 4 58-93-5 3639
29
Atorvastatin Approved Phase 4,Phase 3,Phase 2,Phase 1 134523-00-5 60823
30
Silver sulfadiazine Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 22199-08-2 441244
31
Sulfadiazine Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 68-35-9 5215
32
tannic acid Approved Phase 4,Phase 3,Phase 2,Not Applicable,Early Phase 1 1401-55-4
33
Benzocaine Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable,Early Phase 1 94-09-7, 1994-09-7 2337
34
Heparin Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 9005-49-6 772 46507594
35
Triamcinolone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 124-94-7 31307
36
Metronidazole Approved Phase 4,Phase 2,Phase 3,Not Applicable 443-48-1 4173
37
Povidone-iodine Approved Phase 4,Not Applicable 25655-41-8
38
Povidone Approved Phase 4,Phase 3,Phase 2,Not Applicable 9003-39-8
39
Iodine Approved, Investigational Phase 4,Phase 2,Not Applicable 7553-56-2 807
40
Hyaluronic acid Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 9004-61-9 53477741
41
Pioglitazone Approved, Investigational Phase 4,Phase 2,Phase 3,Not Applicable 111025-46-8 4829
42
Hydrogen peroxide Approved, Vet_approved Phase 4,Not Applicable 7722-84-1 784
43
Acyclovir Approved Phase 4,Phase 3,Phase 2,Phase 1 59277-89-3 2022
44
Histamine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 51-45-6 774
45
Methylcobalamin Approved, Experimental, Investigational Phase 4,Phase 3,Not Applicable 13422-55-4
46
Hydroxocobalamin Approved Phase 4,Phase 3,Not Applicable 13422-51-0 11953898 15589840
47
Acetaminophen Approved Phase 4,Phase 3,Phase 2,Not Applicable 103-90-2 1983
48
leucovorin Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 58-05-9 6006 143
49
Benzydamine Approved Phase 4,Phase 3,Phase 1 100-46-9, 642-72-8 7504
50
Doxycycline Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 564-25-0 54671203

Interventional clinical trials:

(show top 50) (show all 2180)
# Name Status NCT ID Phase Drugs
1 TRANexamic Acid to Reduce Bleeding in BURN Surgery Unknown status NCT03113253 Phase 4 Tranexamic Acid;Placebo
2 Hypoalbuminemia in Burn Patients Unknown status NCT01436292 Phase 4 5% human albumin solution (HAS)
3 Early Fluid Resuscitation With Balanced HES 130/0.4 [6%] in Severe Burn Injury Unknown status NCT01012648 Phase 4 Fluid resuscitation;HES 130/0.4 (6%), Voluven balanced vs. Lactated Ringer's solution
4 Amikacin Pharmacokinetic Profile in Plasma and Tissue After an Administration Using Impregnated Dressings in Burned Patient Population Unknown status NCT02872272 Phase 4 Treatment with Amikacin
5 The Treatment of Bartholin´s Cyst or Abscess With Silver Nitrate Unknown status NCT00786461 Phase 4
6 Clinical Evaluation of T.R.U.E. Test Allergens in Children an Adolescents Unknown status NCT01797562 Phase 4 T.R.U.E. Test Panel 3.2
7 Evaluate the Efficacy, Safety and Tolerability of a Non-hormonal Intravaginal Gel in Postmenopausal Women With Symptoms of Vaginal Dryness. Unknown status NCT02571127 Phase 4 Hidra1
8 Dexmedetomidine on Prevention of Side Effects of Hemabate Unknown status NCT02220361 Phase 4 placebo;low dose dexmedetomidine;high dose dexmedetomidine
9 TRPV Expression in Subjects With Sensitive Skin Unknown status NCT01871883 Phase 4
10 Intranasal Fentanyl for Pain Management Unknown status NCT00882960 Phase 4 intravenous fentanyl;intra-nasal fentanyl
11 Oral Nutrition Impact on Tear Film Unknown status NCT01561040 Phase 4
12 Trial on the Efficacy of Tegaderm Chlorhexidine Gluconate (CHG) in Reducing Catheter Related Bloodstream Infections Unknown status NCT01142934 Phase 4
13 Effect of Fluticasone Proprionate 0.05% on Narrow Band UV-B in Active Vitiligo Unknown status NCT01246921 Phase 4 Fluticasone proprionate 0.05% cream
14 Safety and Tolerability of Acanya Gel in Combination With Atralin Gel for Acne Vulgaris Unknown status NCT01448733 Phase 4 Benzoyl peroxide 2.5%/clindamycin phosphate 1.2% in the morning with with tretinoin 0.05% gel in the evening
15 Superficial Basal Cell Carcinoma Treatment With Topical Photodynamic Therapy With Fractionated 5-aminolevulinic Acid 20% Versus Two Stage Methylaminolevulinate Unknown status NCT01491711 Phase 4 Methylaminolevulinate PDT in 2 sessions;Fractionated 5-aminolevulinic acid hydrochloride 20% gel PDT
16 Perception of Efficacy, Safety and Tolerability of Three Non-hormonal Intravaginal Gels and Hormone Cream Unknown status NCT02987647 Phase 4
17 Postoperative Pain and Angiotensin II Receptor Antagonists Unknown status NCT02513979 Phase 4 Angiotensin type II receptor antagonists
18 CALM-AD Unknown status NCT00142324 Phase 4 Donepezil
19 The Effect of High-dose Remifentanil on Established Sunburn-induced Hyperalgesia in Human Volunteers (HighDose RemiSun) Unknown status NCT01015482 Phase 4 Remifentanil;Midazolam
20 The Effect of Remifentanil on Established Sunburn-induced Hyperalgesia in Human Volunteers Unknown status NCT00811837 Phase 4 Midazolam;Remifentanil
21 Management of Chronic Pain in Military Patients With Injuries Sustained During Active Duty Unknown status NCT01616342 Phase 4
22 Chlorthalidone and HCTZ Impacts on Platelet Activation Unknown status NCT02100462 Phase 4 Chlorthalidone 12.5 mg;Hydrochlorothiazide 25 mg;Aspirin 81 mg
23 Intensive Statin Therapy Effect on Post-Operative Atrial Fibrillation (POAF) Unknown status NCT02029534 Phase 4 Atorvastatin 20 mg;Atorvastatin 80 mg
24 Treatment of Facial Burns With Flammacerium Compared to Flammazine and the Impact of Facial Burns on Psychosocial Wellbeing Completed NCT00297752 Phase 4 ceriumnitrate silversulfadiazine (flammacerium);silversulfadiazine (flammazine)
25 The Effect of Two Versus Ten Days Application of Flammacerium in Partial Thickness Burns Completed NCT00156988 Phase 4 cerium nitrate-silver sulfadiazine (cerium-flamazine)
26 Pharmacokinetics Ertapenem Burns Completed NCT01497990 Phase 4 Ertapenem
27 Comparative Analysis of Cost-effectiveness of Silver Dressing in Burns Completed NCT02108535 Phase 4 Nanocrystalline silver;Silver Sulphadiazine
28 Efficacy and Safety Study of rhGM-CSF Gel to Treat Deep 2nd Thickness Burn Completed NCT01785784 Phase 4 rhGM-CSF Gel
29 Comparison of Wound Bed Establishment in Facial Burns Completed NCT01668030 Phase 4 Enzymatic agent;Bacitracin
30 Continuous Lidocaine Infusion for Management of Perioperative Burn Pain Completed NCT02059902 Phase 4 Lidocaine
31 Comparison of a Water-soluble Topical Antimicrobial to Silver Sulfadiazine in Partial Thickness Burns Completed NCT01926392 Phase 4 water-soluble therapy;silver sulfadiazine
32 Evaluation of Post Burn Rehabilitation Population for Itch Control Completed NCT00782054 Phase 4
33 An Acellular Epithelial Skin Substitute in Deep Partial-thickness Burns Completed NCT01454310 Phase 4
34 Effect of Early Enteral Tube Feeding Nutrition With an Immune Enhancing Diet in Severe Burn Patients Completed NCT00561210 Phase 4
35 Low-dose Hydrocortisone in Acutely Burned Patients Completed NCT00149123 Phase 4 hydrocortisone 200 mg/day
36 Caustic Esophageal Burns in Children and High Doses of Methylprednisolone Completed NCT02002078 Phase 4 methylprednisolon
37 Effect of Silicone Gel Versus Contractubex Phonophoresis for Post-burn Hypertrophic Scars Completed NCT03777891 Phase 4
38 Open, Prosp, Rand. Invest. Evaluating Pain With Mepitel One vs.Bridal Veil and Staples on Split Thickness Skin Grafts Completed NCT01365273 Phase 4
39 Safety and Immunogenicity Study of Recombinant Thrombin (rThrombin) in Pediatric Participants Completed NCT00859547 Phase 4
40 Ethnic Differences in Response to Topical Capsaicin: A Psychophysical Study on Healthy Subjects Completed NCT00655811 Phase 4 Capsaicin;Placebo moisturizing cream
41 Split-face Tolerability Comparison Between MetroGel® 1% vs Finacea® 15% in Subjects With Healthy Skin Completed NCT01139047 Phase 4 metronidazole 1% gel;azelaic acid 15% gel
42 Split-Face Tolerability Comparison Between MetroGel® 1% Versus Finacea® 15% in Subjects With Healthy Skin Completed NCT01139008 Phase 4 metronidazole 1% gel;azelaic acid 15% gel
43 Split-face Tolerability Comparison Between Adapalene-Benzoyl Peroxide Gel Versus Tretinoin Gel Completed NCT01522456 Phase 4 Epiduo Gel;Retin-A Micro Microsphere 0.1%
44 Tolerance of Chlorhexidine Gluconate Vaginal Cleansing Solution Completed NCT03305159 Phase 4 Povidone-Iodine;4% Chlorhexidine Gluconate
45 A Clinical Trial to Study the Effects of Two Drugs, Lycopene and Prednisolone in Patients With Oral Lichen Planus Completed NCT02587117 Phase 4 lycopene;Prednisolone
46 Evaluation of Irritation by Two Facial Gels Applied to Opposite Sides of the Face Completed NCT00919191 Phase 4 Tretinoin gel;Adapalene and Benzoyl peroxide
47 Aruba Aloe Formula F-BC-096 in the Treatment of Split Thickness Donor Site After Wound Closure Completed NCT01213420 Phase 4
48 A Study of Sertraline to Prevent PTSD Completed NCT00182078 Phase 4 Placebo;Sertraline
49 Effect of Topically-Applied Hyaluronic-Acid on Palatal Epithelial Wound Closure Completed NCT02534415 Phase 4 Periodontal dressing material;0.2% Hyaluronic acid gel;0.8% Hyaluronic acid gel
50 Randomized Crossover Trial to Assess the Tolerability of Gonadotropin Releasing Hormone (GnRH) Analogue Administration Completed NCT01161563 Phase 4 Triptorelin pamoate;Leuprolide acetate

Search NIH Clinical Center for Burns

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Burns cell therapies at LifeMap Discovery.

Genetic Tests for Burns

Anatomical Context for Burns

MalaCards organs/tissues related to Burns:

42
Skin, Eye, Testes, Breast, Lung, Brain, Spinal Cord
LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database

Cells/anatomical compartments in embryo or adult related to Burns:
# Tissue Anatomical CompartmentCell Relevance
1 Umbilical Cord Wharton's Jelly Mesenchymal Stem Cells Potential therapeutic candidate

Publications for Burns

Articles related to Burns:

(show top 50) (show all 5960)
# Title Authors Year
1
Red blood cell distribution width is an independent risk factor in the prediction of acute respiratory distress syndrome after severe burns. ( 30686695 )
2019
2
The effect of early change of skin graft dressing on pain and anxiety among burn patients: a two-group randomized controlled clinical trial. ( 30911431 )
2019
3
Steam burn as a late complication of nonsensate DIEP flap after breast reconstruction. ( 30672014 )
2019
4
Malignant melanoma on a thermal burn scar. ( 30703864 )
2019
5
Verrucous carcinoma: An unexpected finding arising from a burn scar. ( 30809566 )
2019
6
A Review of Perforator Flaps for Burn Scar Contractures of Joints. ( 30854364 )
2019
7
Infant burns: A single institution retrospective review. ( 30638666 )
2019
8
Burn camps for burns survivors-Realising the benefits for early adjustment: A systematic review. ( 30638667 )
2019
9
Salvaging the Zone of Stasis in Burns by Pentoxifylline: An Experimental Study in Rats. ( 30649353 )
2019
10
Matriderm and Split Skin Grafting for Full-Thickness Pediatric Facial Burns. ( 30649378 )
2019
11
Flaminal® versus Flamazine® in the treatment of partial thickness burns: a randomized controlled trial on clinical effectiveness and scar quality (FLAM study). ( 30675745 )
2019
12
Feasibility and safety of enzymatic debridement for the prevention of operative escharotomy in circumferential deep burns of the distal upper extremity. ( 30678870 )
2019
13
The diathermy scratch pad: A cheap and efficient tool for chemical and explosion-related burns. ( 30685948 )
2019
14
Hospitalisations with burns in children younger than five years in Portugal, 2011-2015. ( 30686698 )
2019
15
Saving the Melting Eye - Alkali Burns. ( 30690637 )
2019
16
Formula companies' responsibility for burns awareness. ( 30696635 )
2019
17
Medical School Hotline: The Role of Global Health in Medical Education and Biomedical Research at the John A. Burns School of Medicine. ( 30697472 )
2019
18
Burns Due to Application of Raw Garlic to the Feet as a Home Remedy for Fever. ( 30702643 )
2019
19
Survival analysis and mortality predictors of hospitalized severe burn victims in a Malaysian burns intensive care unit. ( 30705904 )
2019
20
A prospective observation on nutrition support in adult patients with severe burns. ( 30714540 )
2019
21
Outcomes of the Use of Hyaluronic Acid-Based Wound Dressings for the Treatment of Partial-Thickness Facial Burns. ( 30715375 )
2019
22
Successful treatment of mixed depth flame burns using enzymatic debridement with Nexobrid™ in a patient with aggressive systemic sclerosis (scleroderma). ( 30719324 )
2019
23
Ensuring Sustainability for UK Burns Services: Workforce Planning for Burns Consultants. ( 30730348 )
2019
24
Head and neck burns are associated with long-term patient-reported dissatisfaction with appearance: A Burn Model System National Database study. ( 30732865 )
2019
25
Burns injuries from e-cigarettes kept in pockets. ( 30733332 )
2019
26
Relationship between the albumin level and the anesthesia method and the effect on clinical course in patients with major burns. ( 30742287 )
2019
27
Childhood Burns Leading to Skeletal and Soft Tissue Deformities: A Case Report. ( 30753524 )
2019
28
Study of negative pressure wound therapy as an adjunct treatment for acute burns in children (SONATA in C): protocol for a randomised controlled trial. ( 30760332 )
2019
29
In hot water: The impact of burn injuries from hot water bottles - Experience of a UK burns unit and review of the literature. ( 30765161 )
2019
30
The role of collagenase ointment in acute burns: a systematic review and meta-analysis. ( 30767636 )
2019
31
Biofilm formation and antibiotic resistance in meticillin-resistant and meticillin-sensitive Staphylococcus aureus isolated from burns. ( 30767648 )
2019
32
The blood parameters and liver function changed inconsistently among children between burns and traumatic injuries. ( 30775182 )
2019
33
Cognitive Behavioral Therapy for Acute Post-trauma Distress: A Randomized, Controlled, Proof-of-Concept Study among Hospitalized Adults with Burns. ( 30776324 )
2019
34
Voice Recovery in a Patient with Inhaled Laryngeal Burns. ( 30783600 )
2019
35
Edaravone alleviates oxidative stress and apoptosis of intestinal epithelium after burns via MAPK pathway. ( 30784254 )
2019
36
Free Vascularized Anterolateral Thigh Fascia Lata Flap for Reconstruction in Electrical Burns of the Severely Damaged Finger. ( 30786284 )
2019
37
Early Initiation of Post-Pyloric Feeding in Patients with Major Burns: Experience in Taiwan Formosa Water Park Dust Explosion Disaster. ( 30787234 )
2019
38
Capacity building in burns and mental health care. ( 30792033 )
2019
39
Incidence of medically attended paediatric burns across the UK. ( 30792345 )
2019
40
Instantaneous Specific Burn Debridement With an Enzymatic Debriding Agent: A New Resource for the Treatment of Burns. ( 30801494 )
2019
41
The effects of different burn dressings on length of telomere and expression of telomerase in children with thermal burns. ( 30805617 )
2019
42
Three Years' Experience of a Novel Biosynthetic Cellulose Dressing in Burns. ( 30809423 )
2019
43
Early resuscitation and management of severe pediatric burns. ( 30824139 )
2019
44
Potential role of adipose tissue and its hormones in burns and critically III patients. ( 30826149 )
2019
45
Epidemiological profile of burns in children in central and southern Tunisia: A 67-case series. ( 30826178 )
2019
46
Liposome-encapsulated farnesol accelerated tissue repair in third-degree burns on a rat model. ( 30833099 )
2019
47
The epidemiology and prognosis of patients with massive burns: A multicenter study of 2483 cases. ( 30837206 )
2019
48
Ablative fractional resurfacing in acute care management of facial burns: a new approach to minimise the need for acute surgical reconstruction. ( 30847482 )
2019
49
High prevalence of imipenem-resistant and metallo-beta-lactamase-producing Pseudomonas aeruginosa in the Burns Hospital in Tunisia: detection of a novel class 1 integron. ( 30849001 )
2019
50
Five Years Experience With Meek Grafting in the Management of Extensive Burns in an Adult Burn Center. ( 30854361 )
2019

Variations for Burns

Expression for Burns

Search GEO for disease gene expression data for Burns.

Pathways for Burns

Pathways related to Burns according to GeneCards Suite gene sharing:

(show all 27)
# Super pathways Score Top Affiliating Genes
1 12.54 HGF IL1B INS TNF
2
Show member pathways
12.22 CSF2 IL1B TNF
3
Show member pathways
12.11 CSF2 IL1B TNF
4
Show member pathways
12.04 ALB IL1B INS TNF
5 11.87 ALB HGF INS
6
Show member pathways
11.83 CSF2 IL1B TNF
7 11.78 HGF IL1B TNF
8 11.75 CSF2 IL1B TNF
9 11.69 CSF2 IL1B TNF
10 11.67 CSF2 IL1B TNF
11 11.63 CSF2 IL1B TNF
12 11.52 CSF2 IL1B TNF
13 11.48 CSF2 IL1B TNF
14
Show member pathways
11.41 CSF2 IL1B TNF
15 11.23 CSF2 IL1B TNF
16 11.2 IL1B TNF
17 11.19 HGF IL1B TNF
18 11.17 IL1B TNF
19 11.12 IL1B TNF
20 11.1 IL1B TNF
21 11.08 ALB INS TTR
22 10.94 IL1B TNF
23 10.8 CSF2 HGF IL1B TNF
24 10.79 IL1B TNF
25 10.72 CSF2 HGF IL1B TNF
26 10.69 CSF2 HGF IL1B TNF
27 10.59 CSF2 IL1B TNF

GO Terms for Burns

Cellular components related to Burns according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.61 ALB CRH CSF2 HGF IL1B INS
2 extracellular space GO:0005615 9.28 ALB CRH CSF2 HGF IL1B INS

Biological processes related to Burns according to GeneCards Suite gene sharing:

(show all 37)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of cell proliferation GO:0008284 9.93 CRH CSF2 IL1B INS
2 positive regulation of cell migration GO:0030335 9.84 HGF IL1B INS
3 cytokine-mediated signaling pathway GO:0019221 9.84 CSF2 HGF IL1B TNF
4 positive regulation of protein kinase B signaling GO:0051897 9.8 HGF INS TNF
5 cellular response to lipopolysaccharide GO:0071222 9.8 CSF2 IL1B TNF
6 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.78 IL1B INS TNF
7 activation of MAPK activity GO:0000187 9.75 HGF IL1B TNF
8 MAPK cascade GO:0000165 9.73 CSF2 HGF IL1B TNF
9 cellular protein metabolic process GO:0044267 9.71 ALB INS SERPINC1 TTR
10 positive regulation of phosphatidylinositol 3-kinase signaling GO:0014068 9.69 HGF INS TNF
11 positive regulation of phagocytosis GO:0050766 9.67 IL1B TNF
12 protein kinase B signaling GO:0043491 9.67 IL1B TNF
13 lipopolysaccharide-mediated signaling pathway GO:0031663 9.67 IL1B TNF
14 negative regulation of interleukin-6 production GO:0032715 9.66 HGF TNF
15 positive regulation of cytokine secretion GO:0050715 9.65 INS TNF
16 positive regulation of interleukin-8 production GO:0032757 9.65 IL1B TNF
17 positive regulation of mitotic nuclear division GO:0045840 9.65 IL1B INS
18 negative regulation of neurogenesis GO:0050768 9.64 IL1B TNF
19 positive regulation of glial cell proliferation GO:0060252 9.62 IL1B TNF
20 positive regulation of protein phosphorylation GO:0001934 9.62 CRH HGF IL1B TNF
21 regulation of I-kappaB kinase/NF-kappaB signaling GO:0043122 9.61 IL1B TNF
22 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.6 IL1B TNF
23 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.59 IL1B TNF
24 regulation of protein secretion GO:0050708 9.58 INS TNF
25 positive regulation of podosome assembly GO:0071803 9.57 CSF2 TNF
26 positive regulation of chemokine biosynthetic process GO:0045080 9.56 IL1B TNF
27 regulation of establishment of endothelial barrier GO:1903140 9.55 IL1B TNF
28 positive regulation of gene expression GO:0010628 9.55 CRH CSF2 IL1B INS TNF
29 positive regulation of neuroinflammatory response GO:0150078 9.52 IL1B TNF
30 positive regulation of fever generation GO:0031622 9.49 IL1B TNF
31 sequestering of triglyceride GO:0030730 9.46 IL1B TNF
32 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 9.43 CSF2 IL1B TNF
33 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.37 IL1B TNF
34 response to immobilization stress GO:0035902 9.34 CRH
35 chronic inflammatory response to antigenic stimulus GO:0002439 9.18 TNF
36 negative regulation of lipid catabolic process GO:0050995 9.13 IL1B INS TNF
37 regulation of signaling receptor activity GO:0010469 9.1 CSF2 HGF IL1B INS TNF TTR

Molecular functions related to Burns according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.43 CSF2 IL1B TNF
2 hormone activity GO:0005179 9.33 CRH INS TTR
3 protease binding GO:0002020 9.13 INS SERPINC1 TNF
4 identical protein binding GO:0042802 9.1 ALB HGF INS SERPINC1 TNF TTR

Sources for Burns

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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