Aliases & Classifications for Burns

Summaries for Burns

MedlinePlus : 43 A burn is damage to your body's tissues caused by heat, chemicals, electricity, sunlight, or radiation. Scalds from hot liquids and steam, building fires and flammable liquids and gases are the most common causes of burns. Another kind is an inhalation injury, caused by breathing smoke. There are three types of burns: First-degree burns damage only the outer layer of skin Second-degree burns damage the outer layer and the layer underneath Third-degree burns damage or destroy the deepest layer of skin and tissues underneath Burns can cause swelling, blistering, scarring and, in serious cases, shock, and even death. They also can lead to infections because they damage your skin's protective barrier. Treatment for burns depends on the cause of the burn, how deep it is, and how much of the body it covers. Antibiotic creams can prevent or treat infections. For more serious burns, treatment may be needed to clean the wound, replace the skin, and make sure the patient has enough fluids and nutrition. NIH: National Institute of General Medical Sciences

MalaCards based summary : Burns is related to complex regional pain syndrome and glossitis. An important gene associated with Burns is TTR (Transthyretin), and among its related pathways/superpathways are Innate Immune System and MAPK signaling pathway. The drugs Amikacin and silver nitrate have been mentioned in the context of this disorder. Affiliated tissues include Umbilical Cord, skin and bone, and related phenotypes are Increased cell death in breast cancer cell lines (MCF10A, MDA-MB-435) and cardiovascular system

Related Diseases for Burns

Diseases related to Burns via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 777)
# Related Disease Score Top Affiliating Genes
1 complex regional pain syndrome 31.9 IL1B TNF
2 glossitis 31.7 IL1B TNF TTR
3 peripheral nervous system disease 31.5 INS TNF TTR
4 carpal tunnel syndrome 31.4 IL1B INS TTR
5 vulvar vestibulitis syndrome 31.3 IL1B TNF
6 chlamydia 31.3 CRP IL1B TNF
7 wells syndrome 31.2 CRP IL1B
8 pyelonephritis 31.1 CRP IL1B TNF
9 toxic shock syndrome 30.5 IL1B SERPINC1 TNF
10 pneumonia 30.1 CRP IL1B TNF
11 purpura 29.9 CRP SERPINC1 TNF
12 decubitus ulcer 29.9 CRP TTR
13 analbuminemia 29.8 CRP TTR
14 post-traumatic stress disorder 29.7 CRH CRP IL1B
15 staphylococcal toxic shock syndrome 29.7 IL1B TNF
16 bacterial sepsis 29.7 CRP TNF
17 critical limb ischemia 29.6 HGF TNF
18 bacterial infectious disease 29.6 CRP CSF2 IL1B TNF
19 duodenal ulcer 29.6 IL1B INS TNF
20 acute insulin response 29.6 CRP INS
21 trichosporonosis 29.5 CSF2 TNF
22 thrombocytosis 29.5 CRP CSF2 SERPINC1
23 respiratory failure 29.5 CRP TNF TTR
24 lung disease 29.5 CSF2 IL1B TNF
25 irritant dermatitis 29.5 IL1B TNF
26 meningitis 29.5 CRP IL1B TNF
27 ischemic heart disease 29.4 CRP TNF
28 diverticulitis 29.4 CRP TNF
29 protein-energy malnutrition 29.4 TNF TTR
30 stomatitis 29.3 CSF2 IL1B TNF
31 autonomic nervous system disease 29.3 INS TTR
32 nonalcoholic steatohepatitis 29.3 INS TNF
33 chronic fatigue syndrome 29.2 CRH IL1B TNF
34 rheumatic disease 29.2 CRP IL1B TNF
35 aphthous stomatitis 29.2 IL1B TNF
36 pulmonary fibrosis, idiopathic 29.1 HGF IL1B TNF
37 diabetes mellitus 29.1 CRP IL1B INS TNF
38 overnutrition 29.0 CRP INS TNF
39 cerebrovascular disease 29.0 CRP INS TNF
40 asthma 28.9 CRH CSF2 IL1B INS TNF
41 rheumatoid arthritis 28.8 CRP CSF2 IL1B TNF TTR
42 body mass index quantitative trait locus 11 28.7 CRH CRP INS TNF
43 arteries, anomalies of 28.6 CRP IL1B INS SERPINC1 TNF
44 heart disease 28.6 CRP IL1B INS SERPINC1 TNF
45 myocardial infarction 28.6 CRP IL1B INS SERPINC1 TNF
46 gastrointestinal system disease 28.5 CRH CRP IL1B INS TNF
47 burning mouth syndrome 12.6
48 burn-mckeown syndrome 12.5
49 burn scar 12.2
50 partial deep dermal and full thickness burns 12.2

Graphical network of the top 20 diseases related to Burns:



Diseases related to Burns

Symptoms & Phenotypes for Burns

GenomeRNAi Phenotypes related to Burns according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased cell death in breast cancer cell lines (MCF10A, MDA-MB-435) GR00104-A-0 8.8 CSF2 INS TNF

MGI Mouse Phenotypes related to Burns:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.01 CRP CSF2 HGF IL1B INS SERPINC1
2 homeostasis/metabolism MP:0005376 9.92 CRH CRP CSF2 IL1B INS SERPINC1
3 hematopoietic system MP:0005397 9.91 CRH CSF2 HGF IL1B INS SERPINC1
4 immune system MP:0005387 9.8 CRH CRP CSF2 IL1B INS SERPINC1
5 liver/biliary system MP:0005370 9.55 CRH HGF INS SERPINC1 TNF
6 no phenotypic analysis MP:0003012 9.35 CRH HGF INS TNF TTR
7 renal/urinary system MP:0005367 9.02 CRH CSF2 INS SERPINC1 TTR

Drugs & Therapeutics for Burns

Drugs for Burns (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 1028)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Amikacin Approved, Investigational, Vet_approved Phase 4,Not Applicable 37517-28-5 37768
2 silver nitrate Approved, Investigational Phase 4,Phase 3,Phase 2
3
Bacitracin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 1405-87-4 10909430 439542
4
Hydrocortisone acetate Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 50-03-3
5
Bronopol Approved Phase 4,Phase 3,Phase 2 52-51-7
6
Hydrocortisone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 50-23-7 5754
7 Parthenolide Approved, Investigational Phase 4,Phase 3 20554-84-1
8
Carboprost Tromethamine Approved Phase 4 58551-69-2 45266502 5284525
9
Dexmedetomidine Approved, Vet_approved Phase 4,Phase 2,Phase 1 113775-47-6 68602 5311068
10
Racepinephrine Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable 329-65-7 838
11
Lidocaine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable 137-58-6 3676
12
Epinephrine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable 51-43-4 5816
13
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 437-38-7 3345
14
Tocopherol Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 1406-66-2 14986
15
Chlorhexidine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 55-56-1 2713 9552079
16
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1 22916-47-8 4189
17
Fluticasone Approved, Experimental Phase 4,Phase 3,Phase 2 90566-53-3 62924
18
Benzoyl peroxide Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 94-36-0 7187
19
Clindamycin Approved, Vet_approved Phase 4,Phase 3,Phase 2 18323-44-9 29029
20
Aminolevulinic acid Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 106-60-5 137
21
Angiotensin II Approved, Investigational Phase 4,Phase 2,Phase 3 11128-99-7, 68521-88-0, 4474-91-3 172198 65143
22
Donepezil Approved Phase 4,Phase 3 120014-06-4 3152
23
Midazolam Approved, Illicit Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 59467-70-8 4192
24
Remifentanil Approved Phase 4,Not Applicable 132875-61-7 60815
25
leucovorin Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 58-05-9 6006 143
26
Dapsone Approved, Investigational Phase 4,Phase 3 80-08-0 2955
27
Chlorthalidone Approved Phase 4 77-36-1 2732
28
Aspirin Approved, Vet_approved Phase 4,Phase 3 50-78-2 2244
29
Hydrochlorothiazide Approved, Vet_approved Phase 4 58-93-5 3639
30
Silver sulfadiazine Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 22199-08-2 441244
31
Sulfadiazine Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 68-35-9 5215
32
Benzocaine Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable,Early Phase 1 94-09-7, 1994-09-7 2337
33 tannic acid Approved Phase 4,Phase 3,Phase 2,Not Applicable,Early Phase 1
34
Metronidazole Approved Phase 4,Phase 2,Phase 3,Not Applicable 443-48-1 4173
35
Povidone Approved Phase 4,Phase 3,Phase 2,Not Applicable 9003-39-8
36
Iodine Approved, Investigational Phase 4,Phase 2,Not Applicable 7553-56-2 807
37
Povidone-iodine Approved Phase 4,Not Applicable 25655-41-8
38
Hyaluronic acid Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 9004-61-9 53477741
39
Pioglitazone Approved, Investigational Phase 4,Phase 2,Phase 3,Not Applicable 111025-46-8 4829
40
Hydrogen peroxide Approved, Vet_approved Phase 4,Not Applicable 7722-84-1 784
41
Triamcinolone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 124-94-7 31307
42
Histamine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 51-45-6, 75614-87-8 774
43
Hydroxocobalamin Approved Phase 4,Phase 3,Not Applicable 13422-51-0 11953898 44475014
44
Methylcobalamin Approved, Experimental, Investigational Phase 4,Phase 3,Not Applicable 13422-55-4
45
Acetaminophen Approved Phase 4,Phase 3,Phase 2 103-90-2 1983
46
Benzydamine Approved Phase 4,Phase 3,Phase 1 100-46-9, 642-72-8 7504
47
Minocycline Approved, Investigational Phase 4,Not Applicable 10118-90-8 5281021
48
Doxycycline Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 564-25-0 54671203
49
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 50-02-2 5743
50
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 1177-87-3

Interventional clinical trials:

(show top 50) (show all 2126)
# Name Status NCT ID Phase Drugs
1 Hypoalbuminemia in Burn Patients Unknown status NCT01436292 Phase 4 5% human albumin solution (HAS)
2 Early Fluid Resuscitation With Balanced HES 130/0.4 [6%] in Severe Burn Injury Unknown status NCT01012648 Phase 4 Fluid resuscitation;HES 130/0.4 (6%), Voluven balanced vs. Lactated Ringer's solution
3 Amikacin Pharmacokinetic Profile in Plasma and Tissue After an Administration Using Impregnated Dressings in Burned Patient Population Unknown status NCT02872272 Phase 4 Treatment with Amikacin
4 The Treatment of Bartholin´s Cyst or Abscess With Silver Nitrate Unknown status NCT00786461 Phase 4
5 Clinical Evaluation of T.R.U.E. Test Allergens in Children an Adolescents Unknown status NCT01797562 Phase 4 T.R.U.E. Test Panel 3.2
6 Evaluate the Efficacy, Safety and Tolerability of a Non-hormonal Intravaginal Gel in Postmenopausal Women With Symptoms of Vaginal Dryness. Unknown status NCT02571127 Phase 4 Hidra1
7 Dexmedetomidine on Prevention of Side Effects of Hemabate Unknown status NCT02220361 Phase 4 placebo;low dose dexmedetomidine;high dose dexmedetomidine
8 TRPV Expression in Subjects With Sensitive Skin Unknown status NCT01871883 Phase 4
9 Intranasal Fentanyl for Pain Management Unknown status NCT00882960 Phase 4 intravenous fentanyl;intra-nasal fentanyl
10 Oral Nutrition Impact on Tear Film Unknown status NCT01561040 Phase 4
11 Trial on the Efficacy of Tegaderm Chlorhexidine Gluconate (CHG) in Reducing Catheter Related Bloodstream Infections Unknown status NCT01142934 Phase 4
12 Effect of Fluticasone Proprionate 0.05% on Narrow Band UV-B in Active Vitiligo Unknown status NCT01246921 Phase 4 Fluticasone proprionate 0.05% cream
13 Safety and Tolerability of Acanya Gel in Combination With Atralin Gel for Acne Vulgaris Unknown status NCT01448733 Phase 4 Benzoyl peroxide 2.5%/clindamycin phosphate 1.2% in the morning with with tretinoin 0.05% gel in the evening
14 Superficial Basal Cell Carcinoma Treatment With Topical Photodynamic Therapy With Fractionated 5-aminolevulinic Acid 20% Versus Two Stage Methylaminolevulinate Unknown status NCT01491711 Phase 4 Methylaminolevulinate PDT in 2 sessions;Fractionated 5-aminolevulinic acid hydrochloride 20% gel PDT
15 Perception of Efficacy, Safety and Tolerability of Three Non-hormonal Intravaginal Gels and Hormone Cream Unknown status NCT02987647 Phase 4
16 Postoperative Pain and Angiotensin II Receptor Antagonists Unknown status NCT02513979 Phase 4 Angiotensin type II receptor antagonists
17 CALM-AD Unknown status NCT00142324 Phase 4 Donepezil
18 The Effect of High-dose Remifentanil on Established Sunburn-induced Hyperalgesia in Human Volunteers (HighDose RemiSun) Unknown status NCT01015482 Phase 4 Remifentanil;Midazolam
19 The Effect of Remifentanil on Established Sunburn-induced Hyperalgesia in Human Volunteers Unknown status NCT00811837 Phase 4 Midazolam;Remifentanil
20 Management of Chronic Pain in Military Patients With Injuries Sustained During Active Duty Unknown status NCT01616342 Phase 4
21 Efficacy and Safety of Aczone 7.5% Gel in the Treatment of Truncal Acne Vulgaris Unknown status NCT02944461 Phase 4 Dapsone 7.5 % gel
22 Chlorthalidone and HCTZ Impacts on Platelet Activation Unknown status NCT02100462 Phase 4 Chlorthalidone 12.5 mg;Hydrochlorothiazide 25 mg;Aspirin 81 mg
23 Intensive Statin Therapy Effect on Post-Operative Atrial Fibrillation (POAF) Unknown status NCT02029534 Phase 4 Atorvastatin 20 mg;Atorvastatin 80 mg
24 Treatment of Facial Burns With Flammacerium Compared to Flammazine and the Impact of Facial Burns on Psychosocial Wellbeing Completed NCT00297752 Phase 4 ceriumnitrate silversulfadiazine (flammacerium);silversulfadiazine (flammazine)
25 The Effect of Two Versus Ten Days Application of Flammacerium in Partial Thickness Burns Completed NCT00156988 Phase 4 cerium nitrate-silver sulfadiazine (cerium-flamazine)
26 Pharmacokinetics Ertapenem Burns Completed NCT01497990 Phase 4 Ertapenem
27 Comparative Analysis of Cost-effectiveness of Silver Dressing in Burns Completed NCT02108535 Phase 4 Nanocrystalline silver;Silver Sulphadiazine
28 Efficacy and Safety Study of rhGM-CSF Gel to Treat Deep 2nd Thickness Burn Completed NCT01785784 Phase 4 rhGM-CSF Gel
29 Comparison of Wound Bed Establishment in Facial Burns Completed NCT01668030 Phase 4 Enzymatic agent;Bacitracin
30 Continuous Lidocaine Infusion for Management of Perioperative Burn Pain Completed NCT02059902 Phase 4 Lidocaine
31 Comparison of a Water-soluble Topical Antimicrobial to Silver Sulfadiazine in Partial Thickness Burns Completed NCT01926392 Phase 4 water-soluble therapy;silver sulfadiazine
32 Evaluation of Post Burn Rehabilitation Population for Itch Control Completed NCT00782054 Phase 4
33 An Acellular Epithelial Skin Substitute in Deep Partial-thickness Burns Completed NCT01454310 Phase 4
34 Effect of Early Enteral Tube Feeding Nutrition With an Immune Enhancing Diet in Severe Burn Patients Completed NCT00561210 Phase 4
35 Low-dose Hydrocortisone in Acutely Burned Patients Completed NCT00149123 Phase 4 hydrocortisone 200 mg/day
36 Caustic Esophageal Burns in Children and High Doses of Methylprednisolone Completed NCT02002078 Phase 4 methylprednisolon
37 Effect of Silicone Gel Versus Contractubex Phonophoresis for Post-burn Hypertrophic Scars Completed NCT03777891 Phase 4
38 Open, Prosp, Rand. Invest. Evaluating Pain With Mepitel One vs.Bridal Veil and Staples on Split Thickness Skin Grafts Completed NCT01365273 Phase 4
39 Safety and Immunogenicity Study of Recombinant Thrombin (rThrombin) in Pediatric Participants Completed NCT00859547 Phase 4
40 Ethnic Differences in Response to Topical Capsaicin: A Psychophysical Study on Healthy Subjects Completed NCT00655811 Phase 4 Capsaicin;Placebo moisturizing cream
41 Split-face Tolerability Comparison Between MetroGel® 1% vs Finacea® 15% in Subjects With Healthy Skin Completed NCT01139047 Phase 4 metronidazole 1% gel;azelaic acid 15% gel
42 Split-Face Tolerability Comparison Between MetroGel® 1% Versus Finacea® 15% in Subjects With Healthy Skin Completed NCT01139008 Phase 4 metronidazole 1% gel;azelaic acid 15% gel
43 Split-face Tolerability Comparison Between Adapalene-Benzoyl Peroxide Gel Versus Tretinoin Gel Completed NCT01522456 Phase 4 Epiduo Gel;Retin-A Micro Microsphere 0.1%
44 A Clinical Trial to Study the Effects of Two Drugs, Lycopene and Prednisolone in Patients With Oral Lichen Planus Completed NCT02587117 Phase 4 lycopene;Prednisolone
45 Tolerance of Chlorhexidine Gluconate Vaginal Cleansing Solution Completed NCT03305159 Phase 4 Povidone-Iodine;4% Chlorhexidine Gluconate
46 Evaluation of Irritation by Two Facial Gels Applied to Opposite Sides of the Face Completed NCT00919191 Phase 4 Tretinoin gel;Adapalene and Benzoyl peroxide
47 A Study of Sertraline to Prevent PTSD Completed NCT00182078 Phase 4 Placebo;Sertraline
48 Aruba Aloe Formula F-BC-096 in the Treatment of Split Thickness Donor Site After Wound Closure Completed NCT01213420 Phase 4
49 Effect of Topically-Applied Hyaluronic-Acid on Palatal Epithelial Wound Closure Completed NCT02534415 Phase 4 Periodontal dressing material;0.2% Hyaluronic acid gel;0.8% Hyaluronic acid gel
50 Randomized Crossover Trial to Assess the Tolerability of Gonadotropin Releasing Hormone (GnRH) Analogue Administration Completed NCT01161563 Phase 4 Triptorelin pamoate;Leuprolide acetate

Search NIH Clinical Center for Burns

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Burns cell therapies at LifeMap Discovery.

Genetic Tests for Burns

Anatomical Context for Burns

MalaCards organs/tissues related to Burns:

41
Skin, Bone, Lung, Breast, Kidney, Testes, Colon
LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database

Cells/anatomical compartments in embryo or adult related to Burns:
# Tissue Anatomical CompartmentCell Relevance
1 Umbilical Cord Wharton's Jelly Mesenchymal Stem Cells Potential therapeutic candidate

Publications for Burns

Articles related to Burns:

(show top 50) (show all 1714)
# Title Authors Year
1
Response to Burns et al. ( 30374959 )
2019
2
Catastrophizing, pain and traumatic stress symptoms following burns: A prospective study. ( 29436110 )
2018
3
Platelet count: A predictor of sepsis and mortality in severe burns; Methodological issues. ( 29395399 )
2018
4
The Use of Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome in Severe Burns Without Inhalation Injury. ( 29901798 )
2018
5
Course and Predictors of Pruritus Following Burns: A Multilevel Analysis. ( 29963682 )
2018
6
Medical Folk Remedy: Two Cases of Garlic Burns. ( 29931078 )
2018
7
Fifteen-minute consultation: Childhood burns: inflicted, neglect or accidental. ( 29934360 )
2018
8
Emergency management of burns: part 2. ( 29969203 )
2018
9
Sildenafil Therapy in Patients With Digital Burns and Raynaud's Syndrome. ( 29931173 )
2018
10
Workforce Planning to Sustain UK Burns Services. ( 29398079 )
2018
11
Multicenter Randomized Controlled Trial to Assess an e-Learning on Acute Burns Management. ( 29931302 )
2018
12
Preclinical assessment of safety and efficacy of intravenous delivery of autologous adipose-derived regenerative cells (ADRCs) in the treatment of severe thermal burns using a porcine model. ( 29958745 )
2018
13
MicroRNA-296 mediated corneal neovascularization in an animal model of corneal burns after alkali exposures. ( 29399058 )
2018
14
Assessment of quality-of-life in patients with face-and-neck burns: The Burn-Specific Health Scale for Face and Neck (BSHS-FN). ( 29958746 )
2018
15
Treatment of corneal chemical alkali burns with a crosslinked thiolated hyaluronic acid film. ( 29429747 )
2018
16
Dystrophic calcinosis cutis within burns, successfully treated with excision and secondary intention wound healing. ( 29430689 )
2018
17
Autonomic nerve activity indexed using 24-h heart rate variability in patients with burns. ( 29409672 )
2018
18
Hyperkalemia in electrical burns: A retrospective study in Colombia. ( 29395406 )
2018
19
Comparative Analysis of Mesenchymal Stem Cells from Bone Marrow, Adipose Tissue, and Dental Pulp as Sources of Cell Therapy for Zone of Stasis Burns. ( 29442525 )
2018
20
A 20-year (1996-2015) trend in deaths as a result of burns in the Transkei subregion of South Africa. ( 29958507 )
2018
21
Physical activity and sedentary behavior following pediatric burns - a preliminary investigation using objective activity monitoring. ( 29449948 )
2018
22
Renal Replacement Therapy in Severe Burns: A Multicenter Observational Study. ( 29931223 )
2018
23
Acute Acalculous Cholecystitis in Burns: A Review. ( 29931066 )
2018
24
Epidemiologic Investigation of Chemical Burns in Southwestern China from 2005 to 2016. ( 29939259 )
2018
25
Response to 'Response to 'Chemical burns: Diphoterine untangled' by KS Alexander [Burns 2017]'. ( 29397236 )
2018
26
Barriers to adequate first-aid for paediatric burns at the scene of the injury. ( 29972718 )
2018
27
Widespread Lichtheimia Infection in a Patient with Extensive Burns: Opportunities for Novel Antifungal Agents. ( 29967971 )
2018
28
Can live music therapy reduce distress and pain in children with burns after wound care procedures? A randomized controlled trial. ( 29395407 )
2018
29
Nose resurfacing with free fasciocutaneous flaps in burns patients. ( 29427442 )
2018
30
Incidence of risk factors for bloodstream infections in patients with major burns receiving intensive care: A retrospective single-center cohort study. ( 29395408 )
2018
31
Children with severe burns display no sex differences in exercise capacity at hospital discharge or adaptation after exercise rehabilitation training. ( 29429746 )
2018
32
Response to 'Chemical burns: Diphoterine untangled' by KS Alexander [Burns 2017]. ( 29397237 )
2018
33
Tracheostomy and mortality in patients with severe burns: A nationwide observational study. ( 29980328 )
2018
34
Early application of continuous high-volume haemofiltration can reduce sepsis and improve the prognosis of patients with severe burns. ( 29980222 )
2018
35
Readability of Spanish language online information for the initial treatment of burns. ( 29402576 )
2018
36
Letter in response to "Acquired methemoglobinemia after hydroxocobalamin administration in a patient with burns and inhalation injury". ( 29164951 )
2018
37
Effect of Music Therapy on Pain Perception, Anxiety, and Opioid Use During Dressing Change Among Patients With Burns in India: A Quasi-experimental, Cross-over Pilot Study. ( 30312157 )
2018
38
A rare approach? Microsurgical breast reconstruction after severe burns. ( 29506333 )
2018
39
Increased Detection Of Carbapenemase-Producing Enterobacteriaceae On Post-Clean Sampling Of Burns Units Wet Surfaces. ( 30321628 )
2018
40
Medical School Hotline: The Department of Medical Technology at the John A. Burns School of Medicine, University of Hawai'i at Manoa. ( 30324004 )
2018
41
Hypertonic saline resuscitation protects against kidney injury induced by severe burns in rats. ( 30327229 )
2018
42
Tissue burns due to contact between a skin surface and highly conducting metallic media in the presence of inter-tissue boiling. ( 30327231 )
2018
43
Prospective analysis of pediatric ocular chemical burns: laundry detergent pods. ( 30342182 )
2018
44
Endotracheal Tube Fixation in Patients With Facial Burns, What Are the Options? ( 30344841 )
2018
45
Role of Heparin Irrigation in the Management of Superficial Burns with Special Reference to Pain Relief and Wound Healing: A Pilot Study. ( 30349764 )
2018
46
Frailty: an independent predictor of burns mortality following in-patient admission. ( 30361081 )
2018
47
Use of Fibrin Sealant for Split-Thickness Skin Grafts in Patients with Hand Burns: A Prospective Cohort Study. ( 30371521 )
2018
48
Restrictive Transfusion Strategy Is More Effective in Massive Burns: Results of the TRIBE Multicenter Prospective Randomized Trial. ( 30371811 )
2018
49
"Consistency an issue?" - A review of UK burns service online information on burns first aid. ( 30377004 )
2018
50
Rational treatment of hydrofluoric acid burns of the fingers. ( 30389254 )
2018

Variations for Burns

Expression for Burns

Search GEO for disease gene expression data for Burns.

Pathways for Burns

Pathways related to Burns according to GeneCards Suite gene sharing:

(show all 27)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.74 CRP CSF2 HGF IL1B INS TNF
2 12.53 HGF IL1B INS TNF
3
Show member pathways
12.22 CSF2 IL1B TNF
4
Show member pathways
12.11 CSF2 IL1B TNF
5
Show member pathways
12 CRP IL1B INS TNF
6
Show member pathways
11.82 CSF2 IL1B TNF
7 11.77 HGF IL1B TNF
8 11.74 CSF2 IL1B TNF
9 11.67 CSF2 IL1B TNF
10 11.65 CSF2 IL1B TNF
11 11.61 CSF2 IL1B TNF
12 11.5 CSF2 IL1B TNF
13 11.46 CSF2 IL1B TNF
14
Show member pathways
11.38 CSF2 IL1B TNF
15 11.19 CSF2 IL1B TNF
16 11.17 IL1B TNF
17 11.17 IL1B TNF
18 11.12 IL1B TNF
19 11.12 HGF IL1B TNF
20 11.1 IL1B TNF
21 10.93 IL1B TNF
22 10.85 CRP TNF
23 10.79 CSF2 HGF IL1B TNF
24 10.77 IL1B TNF
25 10.72 CSF2 HGF IL1B TNF
26 10.69 CSF2 HGF IL1B TNF
27 10.59 CSF2 IL1B TNF

GO Terms for Burns

Cellular components related to Burns according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.61 CRH CRP CSF2 HGF IL1B INS
2 extracellular space GO:0005615 9.28 CRH CRP CSF2 HGF IL1B INS

Biological processes related to Burns according to GeneCards Suite gene sharing:

(show all 41)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of cell proliferation GO:0008284 9.94 CRH CSF2 IL1B INS
2 inflammatory response GO:0006954 9.88 CRH CRP IL1B TNF
3 positive regulation of cell migration GO:0030335 9.85 HGF IL1B INS
4 cellular protein metabolic process GO:0044267 9.85 INS SERPINC1 TTR
5 cytokine-mediated signaling pathway GO:0019221 9.83 CSF2 HGF IL1B TNF
6 positive regulation of protein kinase B signaling GO:0051897 9.81 HGF INS TNF
7 cellular response to lipopolysaccharide GO:0071222 9.81 CSF2 IL1B TNF
8 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.79 IL1B INS TNF
9 activation of MAPK activity GO:0000187 9.77 HGF IL1B TNF
10 MAPK cascade GO:0000165 9.71 CSF2 HGF IL1B TNF
11 positive regulation of phagocytosis GO:0050766 9.68 IL1B TNF
12 protein kinase B signaling GO:0043491 9.68 IL1B TNF
13 acute-phase response GO:0006953 9.68 CRP INS
14 lipopolysaccharide-mediated signaling pathway GO:0031663 9.68 IL1B TNF
15 negative regulation of interleukin-6 production GO:0032715 9.67 HGF TNF
16 positive regulation of phosphatidylinositol 3-kinase signaling GO:0014068 9.67 HGF INS TNF
17 positive regulation of cytokine secretion GO:0050715 9.66 INS TNF
18 positive regulation of interleukin-8 production GO:0032757 9.66 IL1B TNF
19 positive regulation of mitotic nuclear division GO:0045840 9.65 IL1B INS
20 negative regulation of neurogenesis GO:0050768 9.65 IL1B TNF
21 response to immobilization stress GO:0035902 9.65 CRH IL1B
22 positive regulation of glial cell proliferation GO:0060252 9.63 IL1B TNF
23 regulation of I-kappaB kinase/NF-kappaB signaling GO:0043122 9.62 IL1B TNF
24 positive regulation of protein phosphorylation GO:0001934 9.62 CRH HGF IL1B TNF
25 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.61 IL1B TNF
26 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.61 IL1B TNF
27 regulation of protein secretion GO:0050708 9.6 INS TNF
28 positive regulation of podosome assembly GO:0071803 9.58 CSF2 TNF
29 negative regulation of blood vessel diameter GO:0097756 9.57 CRP INS
30 negative regulation of lipid storage GO:0010888 9.56 CRP TNF
31 positive regulation of chemokine biosynthetic process GO:0045080 9.55 IL1B TNF
32 regulation of establishment of endothelial barrier GO:1903140 9.54 IL1B TNF
33 positive regulation of neuroinflammatory response GO:0150078 9.51 IL1B TNF
34 positive regulation of fever generation GO:0031622 9.48 IL1B TNF
35 chronic inflammatory response to antigenic stimulus GO:0002439 9.46 IL1B TNF
36 sequestering of triglyceride GO:0030730 9.43 IL1B TNF
37 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 9.43 CSF2 IL1B TNF
38 regulation of signaling receptor activity GO:0010469 9.43 CSF2 HGF IL1B INS TNF TTR
39 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.37 IL1B TNF
40 negative regulation of lipid catabolic process GO:0050995 9.33 IL1B INS TNF
41 positive regulation of gene expression GO:0010628 9.1 CRH CRP CSF2 IL1B INS TNF

Molecular functions related to Burns according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.43 CSF2 IL1B TNF
2 hormone activity GO:0005179 9.33 CRH INS TTR
3 protease binding GO:0002020 9.13 INS SERPINC1 TNF
4 identical protein binding GO:0042802 9.1 CRP HGF INS SERPINC1 TNF TTR

Sources for Burns

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
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51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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