MCID: CLC004
MIFTS: 38

Calcific Tendinitis

Categories: Muscle diseases

Aliases & Classifications for Calcific Tendinitis

Summaries for Calcific Tendinitis

MalaCards based summary : Calcific Tendinitis is related to tendinitis and tenosynovitis. An important gene associated with Calcific Tendinitis is SPP1 (Secreted Phosphoprotein 1), and among its related pathways/superpathways are Lysosome and Microglia Activation During Neuroinflammation: Microglia Polarization. The drugs Triamcinolone and Prednisolone phosphate have been mentioned in the context of this disorder. Affiliated tissues include bone, pituitary and hypothalamus, and related phenotypes are hematopoietic system and immune system

Wikipedia : 77 Calcific tendinitis is a form of tendinitis, a disorder characterized by deposits of hydroxyapatite (a... more...

Related Diseases for Calcific Tendinitis

Diseases related to Calcific Tendinitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 43)
# Related Disease Score Top Affiliating Genes
1 tendinitis 32.2 CRP LHB SPP1
2 tenosynovitis 10.3 CRP LHB
3 frozen shoulder 10.3
4 liver inflammatory pseudotumor 10.3 CRP UCHL1
5 bone fracture 10.3 CRP TGFB1
6 hypercementosis 10.3 CTSK SPP1
7 cecal disease 10.2 CRP CTRC
8 granulomatous gastritis 10.2 CD68 SPP1
9 testicular infarct 10.2 CRP UCHL1
10 burn scar 10.2 TGFB1 UCHL1
11 pericoronitis 10.2 CD68 CRP
12 rapidly progressive glomerulonephritis 10.2 CRP TGFB1
13 aortic valve disease 1 10.1 CRP SPP1 TGFB1
14 lymphoplasmacyte-rich meningioma 10.1 CD68 UCHL1
15 lichen nitidus 10.1 CD68 UCHL1
16 arthritis 10.1
17 dysphagia 10.1
18 mesenteric lymphadenitis 10.0 CD68 CRP
19 subclavian steal syndrome 10.0 CRP KANTR
20 granular cell tumor 10.0 CD68 UCHL1
21 japanese spotted fever 10.0 CRP KANTR
22 dental abscess 10.0 CRP KANTR
23 sphenoid sinusitis 10.0 CRP KANTR
24 carpal tunnel syndrome 9.9
25 rheumatoid arthritis 9.9
26 osteoid osteoma 9.9
27 mononeuropathy of the median nerve, mild 9.9
28 gout 9.9
29 periarthritis 9.9
30 bursitis 9.9
31 compartment syndrome 9.9
32 neuropathy 9.9
33 meningitis 9.9
34 coccygodynia 9.9
35 synovial chondromatosis 9.9
36 rapidly involuting congenital hemangioma 9.9
37 atlantoaxial subluxation 9.9
38 xanthogranulomatous pyelonephritis 9.9 CD68 CRP
39 petroclival meningioma 9.9 CD68 KANTR
40 subdural empyema 9.8 CRP KANTR
41 pneumatosis cystoides intestinalis 9.8 CD68 CRP
42 trigeminal nerve neoplasm 9.8 CD68 KANTR
43 neurilemmoma of the fifth cranial nerve 9.8 CD68 KANTR

Graphical network of the top 20 diseases related to Calcific Tendinitis:



Diseases related to Calcific Tendinitis

Symptoms & Phenotypes for Calcific Tendinitis

MGI Mouse Phenotypes related to Calcific Tendinitis:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.81 CD68 CTSK DNASE2 LY96 MRC1 POLB
2 immune system MP:0005387 9.61 CD68 CRP CTSK DNASE2 LY96 MRC1
3 skeleton MP:0005390 9.23 CD68 CTSK DNAAF1 DNASE2 POLB SPP1

Drugs & Therapeutics for Calcific Tendinitis

Drugs for Calcific Tendinitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 63)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Triamcinolone Approved, Vet_approved Phase 4,Not Applicable 124-94-7 31307
2
Prednisolone phosphate Approved, Vet_approved Phase 4,Not Applicable 302-25-0
3
Methylprednisolone hemisuccinate Approved Phase 4,Not Applicable 2921-57-5
4
Prednisolone Approved, Vet_approved Phase 4,Not Applicable 50-24-8 5755
5
Methylprednisolone Approved, Vet_approved Phase 4,Not Applicable 83-43-2 6741
6
Racepinephrine Approved Phase 4 329-65-7 838
7
Epinephrine Approved, Vet_approved Phase 4 51-43-4 5816
8
Prednisolone hemisuccinate Experimental Phase 4,Not Applicable 2920-86-7
9 glucocorticoids Phase 4,Not Applicable
10 Hormone Antagonists Phase 4,Not Applicable
11 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Not Applicable
12 Peripheral Nervous System Agents Phase 4,Not Applicable
13 Anti-Inflammatory Agents Phase 4,Not Applicable
14 Hormones Phase 4,Not Applicable
15 Triamcinolone hexacetonide Phase 4,Not Applicable
16 triamcinolone acetonide Phase 4,Not Applicable
17 Triamcinolone diacetate Phase 4,Not Applicable
18 Immunologic Factors Phase 4,Not Applicable
19 Immunosuppressive Agents Phase 4,Not Applicable
20 Antineoplastic Agents, Hormonal Phase 4,Not Applicable
21 Protective Agents Phase 4,Phase 2,Not Applicable
22 Gastrointestinal Agents Phase 4,Not Applicable
23 Antiemetics Phase 4,Not Applicable
24 Autonomic Agents Phase 4,Not Applicable
25 Methylprednisolone Acetate Phase 4,Not Applicable
26 Prednisolone acetate Phase 4,Not Applicable
27 Neuroprotective Agents Phase 4,Not Applicable
28 Sympathomimetics Phase 4
29 Vasoconstrictor Agents Phase 4
30 Respiratory System Agents Phase 4,Not Applicable
31 Adrenergic alpha-Agonists Phase 4
32 Adrenergic Agonists Phase 4
33 Adrenergic Agents Phase 4
34 Epinephryl borate Phase 4
35 Adrenergic beta-Agonists Phase 4
36 Bronchodilator Agents Phase 4
37 Mydriatics Phase 4
38 Neurotransmitter Agents Phase 4
39 Anti-Asthmatic Agents Phase 4,Not Applicable
40 Antidotes Phase 2
41 Chelating Agents Phase 2
42 Antitubercular Agents Phase 2
43 Anti-Infective Agents Phase 2
44 Anti-Bacterial Agents Phase 2
45 sodium thiosulfate Phase 2
46 Antioxidants Phase 2
47
Colchicine Approved Not Applicable 64-86-8 2833 6167
48
Lidocaine Approved, Vet_approved Not Applicable 137-58-6 3676
49
Iodine Approved, Investigational Not Applicable 7553-56-2 807
50
Acetaminophen Approved Not Applicable 103-90-2 1983

Interventional clinical trials:

(show all 20)
# Name Status NCT ID Phase Drugs
1 Efficacy and Tolerance of Ultrasound-guided Needling and Lavage of Calcific Tendinitis of the Rotator Cuff Performed With or Without Subacromial Corticosteroid Injection Completed NCT02403856 Phase 4 Sodium Chloride 0.9%;Methylprednisolone acetate
2 Evaluation of Efficacy and Hypothalamus-pituitary-adrenal Axis Suppression Due to Corticosteroids Intrabursal Injection Completed NCT01652495 Phase 4 methylprednisolone acetate;Triamcinolone Acetonide
3 Efficacy and Tolerance of Sodium Thiosulfate Injection After Ultrasound-guided Percutaneous Irrigation of Calcific Tendinopathy of the Rotator Cuff Completed NCT02538939 Phase 2 Sodium thiosulfate
4 Efficacy Study of Fine Needle Technique on Calcific Tendinitis Terminated NCT00506038 Phase 2
5 Colchicine Treatment for Chronic Shoulder Pain Related to Calcific Tendonitis Unknown status NCT00983177 Not Applicable Colchicine;lactose
6 Ultrasound Guided Needling Versus Ultrasound Guided Corticosteroid Injection Alone, a Randomized Controlled Trial. Unknown status NCT01538758 Not Applicable
7 Comparison of the Effect of Radial Shock Wave, Ultrasound-guided Needle Puncture, and Combination of Both in the Treatment of Calcific Tendinitis of the Shoulder Completed NCT02677103 Not Applicable
8 Platelet-rich Plasma in Calcific Tendinitis Completed NCT02173743 Not Applicable
9 Treatment of Calcific Tendinitis by Ultrasound-guided Needle Lavage Completed NCT01832376 Not Applicable
10 Extracorporeal Shock-wave Therapy for Supraspinatus Calcifying Tendonitis: a Randomized Clinical Trial Comparing Two Different Energy Levels Completed NCT01602653 Not Applicable
11 Radial Shock Wave and Acupuncture for Myofascial Pain Completed NCT02024451 Not Applicable
12 The Effect of Extracorporeal Shock Wave Therapy on Spasticity Completed NCT02221011 Not Applicable
13 Calcific Tendinitis: Comparing Minimally Invasive Modalities Recruiting NCT02367560 Not Applicable Depo medrol
14 The Therapeutic Effect of the Extracorporeal Shock Wave Therapy on Shoulder Calcific Tendinitis Recruiting NCT03779919 Not Applicable
15 Treatment of Calcific Tendinitis of the Rotator Cuff Recruiting NCT02419040 Not Applicable
16 Extracorporeal Shock Wave Therapy Treatment for Nocturnal Leg Cramps Recruiting NCT03864770 Not Applicable
17 Why Does my Shoulder Hurt? Understanding the Presence of Pain in Individuals With Full-thickness Rotator Cuff Tears Recruiting NCT03857009
18 Night Pain in Patients With Rotator Cuff Syndrome Recruiting NCT03894761 Not Applicable
19 Ultrasound Guided Interventions of Calcific Tendonitis of Rotator Cuff (SUCTION) Not yet recruiting NCT02776345 Not Applicable
20 Comparison of 2 Doses of Corticosteroid Subacromial Injections for the Treatment of Painful Shoulder Withdrawn NCT00914836 Not Applicable Betamethasone Sodium Phosphate;1 cc - Betamethasone Sodium Phosphate;2 cc - Betamethasone Sodium Phosphate

Search NIH Clinical Center for Calcific Tendinitis

Genetic Tests for Calcific Tendinitis

Anatomical Context for Calcific Tendinitis

MalaCards organs/tissues related to Calcific Tendinitis:

42
Bone, Pituitary, Hypothalamus, Bone Marrow, Liver

Publications for Calcific Tendinitis

Articles related to Calcific Tendinitis:

(show top 50) (show all 266)
# Title Authors Year
1
Calcific tendinitis at the hip mimicking infective bursitis. ( 30998524 )
2019
2
A pain in the neck: calcific tendinitis of the longus colli muscle. ( 31106755 )
2019
3
Treatment of calcific tendinitis of the rotator cuff with platelet-rich plasma injection: A case report. ( 30995330 )
2019
4
Are corticosteroid injections needed after needling and lavage of calcific tendinitis? Randomised, double-blind, non-inferiority trial. ( 30975645 )
2019
5
Atypical calcific tendinitis involving the long biceps tendon: A rare cause of hemiplegic shoulder pain. ( 30507560 )
2019
6
Osseous Involvement in Calcific Tendinitis-Unusual in the Usual. ( 30303267 )
2019
7
Restriction of Passive Glenohumeral Abduction Combined With Normal Passive External Rotation Is a Diagnostic Feature of Calcific Tendinitis. ( 29450206 )
2018
8
Osteoid osteoma of the scaphoid bone associated with flexor carpi radialis calcific tendinitis and treated with CT-guided RF ablation. ( 29541786 )
2018
9
Long-Term Course of Shoulders After Ultrasound Therapy for Calcific Tendinitis: Results of the 10-Year Follow-Up of a Randomized Controlled Trial. ( 29613883 )
2018
10
Acute Calcific Tendinitis of the Longus Colli Muscle. ( 29729242 )
2018
11
Unusual presentation of calcific tendinitis of the iliopsoas tendon in a 28-year-old female. ( 29788540 )
2018
12
Clinical and Imaging Features of Longus Colli Calcific Tendinitis: An Analysis of Ten Cases. ( 29854344 )
2018
13
Large bone erosion due to calcific tendinitis of the distal biceps tendon. ( 28366614 )
2018
14
Rotator Cuff Calcific Tendinitis: Ultrasound-Guided Needling and Lavage Versus Subacromial Corticosteroids: Five-Year Outcomes of a Randomized Controlled Trial. ( 28898104 )
2017
15
Acute Calcific Tendinitis of the Longus Colli Muscle: Report of Two Cases and Review of the Literature. ( 29067221 )
2017
16
Acute calcific tendinitis of the longus colli muscle masquerading as a retropharyngeal abscess: A case report and review of the literature. ( 29145108 )
2017
17
Case reports about an overlooked cause of neck pain: calcific tendinitis of the longus colli: Case reports. ( 29145245 )
2017
18
Examination of concomitant glenohumeral pathologies in patients treated arthroscopically for calcific tendinitis of the shoulder and implications for routine diagnostic joint exploration. ( 29162079 )
2017
19
Calcific Tendinitis of the Shoulder. ( 29189629 )
2017
20
Calcific Tendinitis of the Shoulder. ( 29189630 )
2017
21
Prognostic factors for the outcome of extracorporeal shockwave therapy for calcific tendinitis of the shoulder. ( 29212688 )
2017
22
Calcific tendinitis of the gluteus maximus of a 53-year-old woman. ( 29255101 )
2017
23
Outcome of Needle Fenestration, Subacromial Steroid and Diclofenac Phonophoresis in Acute Calcific Tendinitis of Shoulder. ( 29255320 )
2017
24
Acute Calcific Tendinitis of the Index Finger in a Child. ( 28832199 )
2017
25
Ultrasound guided Needling vs Radial Shockwave Therapy in calcific tendinitis of the shoulder: A prospective randomized trial. ( 28831234 )
2017
26
Acute Prevertebral Calcific Tendinitis. ( 28502954 )
2017
27
Acute calcific tendinitis of the longus colli muscle. ( 28494486 )
2017
28
Comparative Effectiveness of Nonoperative Treatments for Chronic Calcific Tendinitis of the Shoulder: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials. ( 28400182 )
2017
29
Arthroscopic Removal and Tendon Repair for Refractory Rotator Cuff Calcific Tendinitis of the Shoulder. ( 28331139 )
2017
30
Bone scan findings in calcific tendinitis at the gluteus maximus insertion: some illustrative cases. ( 28228904 )
2017
31
The effects of therapeutic exercise using PNF on the size of calcium deposits, pain self-awareness, and shoulder joint function in a calcific tendinitis patient: a case study. ( 28210065 )
2017
32
Acute neck pain in the ED: Consider longus colli calcific tendinitis vs meningitis. ( 28139306 )
2017
33
Acute calcific tendinitis of gluteus maximus tendon due to tumoral calcium pyrophosphate dihydrate deposition disease. ( 28036155 )
2017
34
Acute calcific tendinitis of the longus colli muscle. ( 27506285 )
2017
35
Calcific Tendinitis of the Gluteus Maximus in a Golfer. ( 27337668 )
2016
36
Acute Calcific Tendinitis in the Distal Interphalangeal Joint. ( 27218036 )
2016
37
Needle aspiration of calcific deposits (NACD) for calcific tendinitis is safe and effective: Six months follow-up of clinical results and complications in a series of 431 patients. ( 26971409 )
2016
38
Radiological and clinical predictors of long-term outcome in rotator cuff calcific tendinitis. ( 26945760 )
2016
39
Calcific Tendinitis of the Longus Colli. ( 26935386 )
2016
40
Why Do Tendons Hurt? Lessons from the Study of Calcific Tendinitis: Commentary on an article by Lisa Hackett, AMS, et al.: "Are the Symptoms of Calcific Tendinitis Due to Neoinnervation and/or Neovascularization?". ( 26842418 )
2016
41
Are the Symptoms of Calcific Tendinitis Due to Neoinnervation and/or Neovascularization? ( 26842408 )
2016
42
Misconceived Retropharyngeal Calcific Tendinitis during Management of Myofascial Neck Pain Syndrome. ( 26839671 )
2016
43
Calcific tendinitis of the rotator cuff. ( 26807357 )
2016
44
Ultrasound imaging-guided percutaneous treatment of rotator cuff calcific tendinitis: success in short-term outcome. ( 26607641 )
2016
45
Calcific tendinitis of the rotator cuff: state of the art in diagnosis and treatment. ( 26163832 )
2016
46
A Rare Cause of Dysphagia to Remember: Calcific Tendinitis of the Longus Colli Muscle. ( 28100997 )
2016
47
Effect of extracorporeal shock wave therapy on the shoulder joint functional status of patients with calcific tendinitis. ( 27799684 )
2016
48
Poster 185 Chronic Intractable Calcific Tendinitis of Common Extensor Tendon Successfully Treated with Ultrasound-Guided Barbotage Combined with Extracorporeal Shock Wave Therapy: A Case Report. ( 27672949 )
2016
49
Long-Term Outcome of Ultrasound Therapy for Calcific Tendinitis of the Shoulder: Results of a RCT. ( 27672757 )
2016
50
Calcific tendinitis of the longus colli muscle: A rare cause of neck pain. ( 27625274 )
2016

Variations for Calcific Tendinitis

Expression for Calcific Tendinitis

Search GEO for disease gene expression data for Calcific Tendinitis.

Pathways for Calcific Tendinitis

Pathways related to Calcific Tendinitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.42 CD68 CTSK DNASE2
2 10.65 CD68 MRC1 TGFB1
3 10.16 CTSK SPP1

GO Terms for Calcific Tendinitis

Biological processes related to Calcific Tendinitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 response to vitamin D GO:0033280 9.32 SPP1 TGFB1
2 lymph node development GO:0048535 9.26 POLB TGFB1
3 positive regulation of superoxide anion generation GO:0032930 9.16 CRP TGFB1
4 inflammatory response GO:0006954 9.02 CRP LY96 POLB SPP1 TGFB1
5 salivary gland morphogenesis GO:0007435 8.96 POLB TGFB1

Sources for Calcific Tendinitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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