MCID: CLC004
MIFTS: 33

Calcific Tendinitis

Categories: Muscle diseases

Aliases & Classifications for Calcific Tendinitis

MalaCards integrated aliases for Calcific Tendinitis:

Name: Calcific Tendinitis 12 54 15 70 32

Classifications:



External Ids:

Disease Ontology 12 DOID:14181
ICD9CM 34 726.11
SNOMED-CT 67 239957000
ICD10 32 M65.2 M75.3
UMLS 70 C0158303 C0521515

Summaries for Calcific Tendinitis

MalaCards based summary : Calcific Tendinitis is related to tendinitis and bursitis. An important gene associated with Calcific Tendinitis is SPP1 (Secreted Phosphoprotein 1), and among its related pathways/superpathways are Lysosome and Osteoclast Signaling. The drugs Dexamethasone and Dexamethasone acetate have been mentioned in the context of this disorder. Affiliated tissues include bone, bone marrow and prostate, and related phenotype is skeleton.

Wikipedia : 73 Calcific tendinitis is a form of tendinitis, a disorder characterized by deposits of hydroxyapatite (a... more...

Related Diseases for Calcific Tendinitis

Diseases related to Calcific Tendinitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 60)
# Related Disease Score Top Affiliating Genes
1 tendinitis 32.2 SPP1 CRP
2 bursitis 30.8 PHOSPHO1 CRP
3 frozen shoulder 10.6
4 dysphagia 10.5
5 tendinopathy 10.4
6 inflammatory spondylopathy 10.3
7 spondylitis 10.3
8 rapidly involuting congenital hemangioma 10.2
9 periarthritis 10.2
10 septic arthritis 10.2
11 shoulder impingement syndrome 10.1
12 calcinosis 10.1
13 compartment syndrome 10.1
14 chronic pain 10.1
15 pustulosis of palm and sole 10.1 CRP AP1S3
16 mineral metabolism disease 10.1 SPP1 CRP
17 bone giant cell tumor 10.0 SPP1 CTSK
18 arterial calcification of infancy 10.0 SPP1 PHOSPHO1
19 root resorption 10.0 SPP1 CTSK
20 hypophosphatasia 10.0 SPP1 PHOSPHO1
21 carpal tunnel syndrome 10.0
22 rheumatoid arthritis 10.0
23 torticollis 10.0
24 osteoid osteoma 10.0
25 epidural abscess 10.0
26 gout 10.0
27 epicondylitis 10.0
28 pharyngitis 10.0
29 hidradenitis suppurativa 10.0
30 hidradenitis 10.0
31 pulmonary tuberculosis 10.0
32 hemarthrosis 10.0
33 neuropathy 10.0
34 meningitis 10.0
35 tenosynovitis 10.0
36 47,xyy 10.0
37 coccygodynia 10.0
38 synovial chondromatosis 10.0
39 carotid stenosis 10.0 SPP1 CRP
40 cauda equina syndrome 9.9 CRP BMP2
41 tympanosclerosis 9.9 SPP1 BMP2
42 gingival recession 9.9 CRP BMP2
43 osteofibrous dysplasia 9.9 SPP1 BMP2
44 spondylolisthesis 9.9 CRP BMP2
45 spondylosis 9.9 CRP BMP2
46 cartilage disease 9.9 CRP BMP2
47 hyperphosphatemia 9.9 SPP1 CRP
48 spondylolysis 9.8 CTSK BMP2
49 aortic valve disease 2 9.8 SPP1 CRP BMP2
50 tooth resorption 9.7 SPP1 CTSK BMP2

Graphical network of the top 20 diseases related to Calcific Tendinitis:



Diseases related to Calcific Tendinitis

Symptoms & Phenotypes for Calcific Tendinitis

MGI Mouse Phenotypes related to Calcific Tendinitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 skeleton MP:0005390 9.17 BMP2 CHAD CTRC CTSK HYAL1 PHOSPHO1

Drugs & Therapeutics for Calcific Tendinitis

Drugs for Calcific Tendinitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 41)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dexamethasone Approved, Investigational, Vet_approved Phase 4 50-02-2 5743
2
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 4 1177-87-3
3
Cortisone Experimental Phase 4 53-06-5 222786
4 Gastrointestinal Agents Phase 4
5 Hormones Phase 4
6 Antiemetics Phase 4
7 Hormone Antagonists Phase 4
8 Antineoplastic Agents, Hormonal Phase 4
9 Anti-Inflammatory Agents Phase 4
10 glucocorticoids Phase 4
11
Methylprednisolone Approved, Vet_approved Phase 2 83-43-2 6741
12
Methylprednisolone hemisuccinate Approved Phase 2 2921-57-5
13
Prednisolone Approved, Vet_approved Phase 2 50-24-8 5755
14
Prednisolone acetate Approved, Vet_approved Phase 2 52-21-1
15
Prednisolone phosphate Approved, Vet_approved Phase 2 302-25-0
16
Lidocaine Approved, Vet_approved Phase 2 137-58-6 3676
17
Prednisolone hemisuccinate Experimental Phase 2 2920-86-7
18 Methylprednisolone Acetate Phase 2
19 Protective Agents Phase 2
20 Pharmaceutical Solutions Phase 2
21 Antidotes Phase 2
22 Chelating Agents Phase 2
23 Antioxidants Phase 2
24 Anti-Bacterial Agents Phase 2
25 sodium thiosulfate Phase 2
26 Anti-Infective Agents Phase 2
27 Antitubercular Agents Phase 2
28
Triamcinolone Approved, Vet_approved 124-94-7 31307
29
Iodine Approved, Investigational 7553-56-2 807
30
Cadexomer iodine Experimental 94820-09-4
31 Triamcinolone diacetate
32 Triamcinolone hexacetonide
33 triamcinolone acetonide
34 Neuroprotective Agents
35 Calcium, Dietary
36 Sodium Channel Blockers
37 Anesthetics, Local
38 Anti-Arrhythmia Agents
39 Anesthetics
40 Diuretics, Potassium Sparing
41
Calcium Nutraceutical 7440-70-2 271

Interventional clinical trials:

(show all 15)
# Name Status NCT ID Phase Drugs
1 Efficacy and Tolerance of Ultrasound-guided Needling and Lavage of Calcific Tendinitis of the Rotator Cuff Performed With or Without Subacromial Corticosteroid Injection: A Double Blind Controlled Study Completed NCT02403856 Phase 4 Sodium Chloride 0.9%;Methylprednisolone acetate
2 Calcific Tendonitis Treatment: Barbotage vs. Barbotage With Cortisone Injection: A Randomized Controlled Double-Blind Study Not yet recruiting NCT04126278 Phase 4 Barbotage;Dexamethasone
3 Efficacy and Tolerance of Sodium Thiosulfate Injection After Ultrasound-guided Percutaneous Irrigation of Calcific Tendinopathy of the Rotator Cuff Completed NCT02538939 Phase 2 Sodium thiosulfate
4 Efficacy of Sodium Thiosulfate in Shoulder Pain in Calcific Tendinitis of the Rotator Cuff Recruiting NCT04251832 Phase 2 Sodium Thiosulfate
5 Phase 2 Study of the Fine Needle Technique on Calcific Tendinitis Terminated NCT00506038 Phase 2
6 Effectiveness of Extracorporeal Shockwave Therapy on the Patients With Nocturnal Leg Cramps - Possible Related to Myofascial Trigger Point in the Gastrocnemius Muscle Unknown status NCT03864770
7 The Therapeutic Effect of the Extracorporeal Shock Wave Therapy on Shoulder Calcific Tendinitis Unknown status NCT03779919
8 Treatment of Calcifying Tendinitis of the Shoulder: Ultrasound Guided Needling With Subacromial Corticosteroid Injection Versus Ultrasound Guided Subacromial Corticosteroid Injection Only, a Randomized Controlled Trial. Unknown status NCT01538758
9 Comparison of the Effect of Radial Shock Wave, Ultrasound-guided Needle Puncture, and Combination of Both in the Treatment of Calcific Tendinitis of the Shoulder Completed NCT02677103
10 The Effect of Extracorporeal Shock Wave Therapy on Spasticity Completed NCT02221011
11 Calcific Tendinitis of the Rotator Cuff: a Randomized Controlled Trial to the Effects of the Adjuvant Application of Platelet-rich Plasma After Needle Aspiration of Calcific Deposits Completed NCT02173743
12 Treatment of Calcific Tendinitis by Ultrasound-guided Needle Lavage Completed NCT01832376
13 The Effectiveness of 4500 Joule Therapeutic Ultrasound in the Treatment of Calcific Tendinitis of the Shoulder Recruiting NCT04822779
14 Calcific Tendinitis: Comparing Minimally Invasive Modalities Recruiting NCT02367560 Depo medrol
15 Treatment of Calcific Tendinitis of the Rotator Cuff - a Multi-centre, Randomized and Sham Controlled Trial (KALK Study) Active, not recruiting NCT02419040

Search NIH Clinical Center for Calcific Tendinitis

Genetic Tests for Calcific Tendinitis

Anatomical Context for Calcific Tendinitis

MalaCards organs/tissues related to Calcific Tendinitis:

40
Bone, Bone Marrow, Prostate

Publications for Calcific Tendinitis

Articles related to Calcific Tendinitis:

(show top 50) (show all 472)
# Title Authors PMID Year
1
Factors Associated With Clinical Improvement and the Disappearance of Calcifications After Ultrasound-Guided Percutaneous Lavage of Rotator Cuff Calcific Tendinopathy: A Post Hoc Analysis of a Randomized Controlled Trial. 61
33719606 2021
2
Calcific tendinitis of the shoulder in the Korean population: demographics and its relation with coexisting rotator cuff tear. 61
33652508 2021
3
Efficacy of Adjuvant Application of Platelet-Rich Plasma After Needle Aspiration of Calcific Deposits for the Treatment of Rotator Cuff Calcific Tendinitis: A Double-Blinded, Randomized Controlled Trial With 2-Year Follow-up. 61
33566629 2021
4
Is common the rotator cuff tear in the calcific tendinitis? 61
33652504 2021
5
Favourable clinical outcome of shoulder manipulation for chronic calcific tendinitis associated with shoulder stiffness: A case report. 61
33546934 2021
6
The Impact of Minimally Invasive Treatment for Rotator Cuff Calcific Tendinitis on Self-Reported Work Ability and Sick Leave. 61
33376997 2020
7
Isolated calcific tendinitis at the posterosuperior labrum: a rare case study. 61
33330259 2020
8
Diagnosis and treatment of calcific tendinitis of the shoulder. 61
33330261 2020
9
Extracorporeal shock wave therapy treatment of painful hematoma in the calf: A case report. 61
33392338 2020
10
Retropharyngeal calcific tendinitis: A rare, benign, but painful condition with stiff neck. 61
33304727 2020
11
Seasonal variation in the onset of acute calcific tendinitis of rotator cuff. 61
33183291 2020
12
Interactive associations of sex and hyperlipidemia with calcific tendinitis of the shoulder in Taiwanese adults. 61
33181720 2020
13
Differentiation of retropharyngeal calcific tendinitis and retropharyngeal abscess: a case series and review of the literature. 61
32449026 2020
14
Radiographic assessment of calcifying tendinitis of the rotator cuff : an inter- and intraobserver study. 61
33581038 2020
15
Quantifying the minimal and substantial clinical benefit of the Constant-Murley score and the Disabilities of the Arm, Shoulder and Hand score in patients with calcific tendinitis of the rotator cuff. 61
32939494 2020
16
Prevalence of rotator cuff diseases in adults older than 40 years in or near Chuncheon city, Korea. 61
33330246 2020
17
Ultrasound features of painful intraosseous migration of pectoralis major tendinous calcifications with follow-up. 61
31228123 2020
18
MRI findings in calcific deposits in and around shoulder: atypical locations beyond supraspinatus. 61
32131976 2020
19
Acute Calcific Tendinitis of the Longus Colli. 61
32803219 2020
20
Acute Calcific Tendinitis of the Longus Colli: Not All Retropharyngeal Fluid is an Abscess. 61
32720813 2020
21
A rare case of calcific tendinitis of biceps femoris presenting with lateral knee pain. 61
32774045 2020
22
Comparing Ultrasound-Guided Needling Combined With a Subacromial Corticosteroid Injection Versus High-Energy Extracorporeal Shockwave Therapy for Calcific Tendinitis of the Rotator Cuff: A Randomized Controlled Trial. 61
32114063 2020
23
Prognostic factors for the outcome of needle aspiration of calcific deposits for rotator cuff calcific tendinitis. 61
32140816 2020
24
Return to Work Following Shoulder Surgery: An Analysis of 1,773 Cases. 61
32803105 2020
25
MRI findings in intraosseous extension of calcific supraspinatus tendonitis. 61
32419898 2020
26
Recovery pattern after arthroscopic treatment for calcific tendinitis of the shoulder. 61
32430269 2020
27
Unusual and important cause of acute neck pain: Longus colli calcific tendinitis. 61
32309038 2020
28
Exposure-response relationships between cumulative occupational shoulder exposures and different diagnoses related to surgery for subacromial impingement syndrome. 61
31760468 2020
29
The effects of shockwave therapy on musculoskeletal conditions based on changes in imaging: a systematic review and meta-analysis with meta-regression. 61
32345281 2020
30
Indications for Arthroscopic Subacromial Decompression. A Level V Evidence Clinical Guideline. 61
31882271 2020
31
Surgical treatment of peroneal calcific tendinitis in an uncommon localization: A case report. 61
32185051 2020
32
Tolerance and effect of sodium thiosulfate in calcific tendinitis of the rotator cuff. 61
31673978 2020
33
Dose-Response Relationship between Physical Workload and Specific Shoulder Diseases-A Systematic Review with Meta-Analysis. 61
32075183 2020
34
Calcification of the Anterior Acromial Insertion of the Deltoid Muscle. 61
33101746 2020
35
Calcific tendinopathy of the shoulder with intraosseous extension: experience with arthroscopic treatment and review of the literature. 61
31734180 2020
36
Acupuncture for symptomatic rotator cuff disease: Protocol for a systematic review and meta-analysis. 61
31914084 2020
37
Calcific Tendinitis in the Elbow Presented as Acute Tennis Elbow. 61
32001866 2020
38
Calcific Tendinitis of the Supraspinatus Tendon in an Infant. 61
32695543 2020
39
Calcific Tendinitis at the Hip Mimicking Infective Bursitis. 61
30998524 2019
40
Calcific tendinitis: intramuscular and intraosseous migration. 61
31650966 2019
41
Shoulder Pseudodislocation Associated with Calcific Tendinitis/Bursitis and Diagnosed by Point of Care Ultrasound. 61
31677978 2019
42
Longus Colli Tendinitis: The Lost Twin of Retropharyngeal Abscess. 61
31742062 2019
43
Changing appearance of intraosseous calcific tendinitis in the shoulder with time: A case report. 61
31462951 2019
44
Arthroscopic Treatment of an Unusual Intramuscular Calcium Hydroxyapatite Crystal Deposit on the Rotator Cuff. 61
31921579 2019
45
Risk Factors for Persistent Shoulder Pain After Cervical Spine Surgery. 61
31663284 2019
46
Neuralgic Amyotrophy in a 66-year-old Hiker: a Case Report. 61
31762709 2019
47
The impact of pre-existing shoulder diseases and traumatic injuries of the shoulder on adhesive capsulitis in adult population: A population-based nested case-control study. 61
31574829 2019
48
Unusual presentation of calcific tendinitis of the iliopsoas tendon in a 28-year-old female. 61
29788540 2019
49
Management Strategies for Rotator Cuff Defects After Calcific Tendinitis Debridement. 61
31737483 2019
50
Comparison of Radial Extracorporeal Shock Wave Therapy and Traditional Physiotherapy in Rotator Cuff Calcific Tendinitis Treatment. 61
31598593 2019

Variations for Calcific Tendinitis

Expression for Calcific Tendinitis

Search GEO for disease gene expression data for Calcific Tendinitis.

Pathways for Calcific Tendinitis

Pathways related to Calcific Tendinitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.91 HYAL1 CTSK AP1S3
2 10.16 SPP1 CTSK

GO Terms for Calcific Tendinitis

Cellular components related to Calcific Tendinitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.43 SPP1 HYAL1 CTSK CRP CHAD BMP2
2 extracellular region GO:0005576 9.23 TUFT1 SPP1 HYAL1 CTSK CTRC CRP

Biological processes related to Calcific Tendinitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 bone mineralization GO:0030282 9.26 TUFT1 BMP2
2 inflammatory response GO:0006954 9.26 SPP1 HYAL1 CRP BMP2
3 biomineral tissue development GO:0031214 9.16 TUFT1 SPP1
4 bone mineralization involved in bone maturation GO:0035630 8.62 PHOSPHO1 BMP2

Sources for Calcific Tendinitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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