MCID: CLC010
MIFTS: 32

Calcifying Epithelial Odontogenic Tumor

Categories: Rare diseases

Aliases & Classifications for Calcifying Epithelial Odontogenic Tumor

MalaCards integrated aliases for Calcifying Epithelial Odontogenic Tumor:

Name: Calcifying Epithelial Odontogenic Tumor 54 74
Pindborg Tumor 54
Ceot 54

Classifications:



External Ids:

UMLS 74 C0334574

Summaries for Calcifying Epithelial Odontogenic Tumor

MalaCards based summary : Calcifying Epithelial Odontogenic Tumor, also known as pindborg tumor, is related to ameloblastoma and rapidly involuting congenital hemangioma. An important gene associated with Calcifying Epithelial Odontogenic Tumor is AMBN (Ameloblastin), and among its related pathways/superpathways are Pathways in cancer and Hedgehog Pathway. Affiliated tissues include bone, eye and breast, and related phenotypes are craniofacial and digestive/alimentary

Wikipedia : 77 The calcifying epithelial odontogenic tumor (CEOT), also known as a Pindborg tumor, is an odontogenic... more...

Related Diseases for Calcifying Epithelial Odontogenic Tumor

Diseases related to Calcifying Epithelial Odontogenic Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 44)
# Related Disease Score Top Affiliating Genes
1 ameloblastoma 30.3 AMBN KRT8 PTCH1
2 rapidly involuting congenital hemangioma 10.2
3 tuberous sclerosis 1 10.1
4 myeloma, multiple 10.1
5 osteoblastoma 10.1
6 tuberous sclerosis 10.1
7 stomatitis 10.1
8 ulcerative stomatitis 10.1
9 prostate squamous cell carcinoma 10.1 KRT8 TP53
10 pleomorphic carcinoma 10.1 KRT8 TP53
11 basaloid squamous cell carcinoma 10.0 KRT8 TP53
12 adenosquamous carcinoma 10.0 KRT8 TP53
13 cervical squamous cell carcinoma 10.0 KRT8 TP53
14 sweat gland cancer 10.0 KRT8 TP53
15 focal epithelial hyperplasia 10.0 GLI2 TP53
16 ductal carcinoma in situ 9.9 KRT8 TP53
17 merkel cell carcinoma 9.9 KRT8 TP53
18 brooke-spiegler syndrome 9.9 KRT8 PTCH1
19 breast ductal carcinoma 9.9 KRT8 TP53
20 cerebellar liponeurocytoma 9.9 PTCH1 TP53
21 childhood medulloblastoma 9.9 PTCH1 TP53
22 keratocystic odontogenic tumor 9.9 PTCH1 TP53
23 adult medulloblastoma 9.9 PTCH1 TP53
24 holoprosencephaly, recurrent infections, and monocytosis 9.9 GLI2 PTCH1
25 holoprosencephaly 9.9 GLI2 PTCH1
26 septopreoptic holoprosencephaly 9.8 GLI2 PTCH1
27 transitional cell carcinoma 9.8 KRT8 TP53
28 midline interhemispheric variant of holoprosencephaly 9.8 GLI2 PTCH1
29 nodular medulloblastoma 9.8 GLI2 PTCH1
30 alobar holoprosencephaly 9.8 GLI2 PTCH1
31 lobar holoprosencephaly 9.8 GLI2 PTCH1
32 microform holoprosencephaly 9.8 GLI2 PTCH1
33 semilobar holoprosencephaly 9.8 GLI2 PTCH1
34 greig cephalopolysyndactyly syndrome 9.8 GLI2 PTCH1
35 central nervous system cancer 9.8 PTCH1 TP53
36 bardet-biedl syndrome 17 9.8 GLI2 PTCH1
37 papilloma 9.8 KRT8 TP53
38 nervous system cancer 9.8 PTCH1 TP53
39 basal cell nevus syndrome 9.8 GLI2 PTCH1
40 autosomal genetic disease 9.7 PTCH1 TP53
41 infratentorial cancer 9.6 GLI2 PTCH1 TP53
42 medulloblastoma 9.5 GLI2 PTCH1 TP53
43 xeroderma pigmentosum, variant type 9.5 PTCH1 TP53
44 basal cell carcinoma 9.3 GLI2 KRT8 PTCH1 TP53

Graphical network of the top 20 diseases related to Calcifying Epithelial Odontogenic Tumor:



Diseases related to Calcifying Epithelial Odontogenic Tumor

Symptoms & Phenotypes for Calcifying Epithelial Odontogenic Tumor

MGI Mouse Phenotypes related to Calcifying Epithelial Odontogenic Tumor:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 craniofacial MP:0005382 9.71 AMBN GLI2 PTCH1 TP53
2 digestive/alimentary MP:0005381 9.67 GLI2 KRT8 PTCH1 TP53
3 growth/size/body region MP:0005378 9.65 AMBN GLI2 KRT8 PTCH1 TP53
4 embryo MP:0005380 9.62 GLI2 KRT8 PTCH1 TP53
5 hearing/vestibular/ear MP:0005377 9.46 GLI2 KRT8 PTCH1 TP53
6 reproductive system MP:0005389 9.26 GLI2 KRT8 PTCH1 TP53
7 skeleton MP:0005390 8.92 AMBN GLI2 PTCH1 TP53

Drugs & Therapeutics for Calcifying Epithelial Odontogenic Tumor

Search Clinical Trials , NIH Clinical Center for Calcifying Epithelial Odontogenic Tumor

Genetic Tests for Calcifying Epithelial Odontogenic Tumor

Anatomical Context for Calcifying Epithelial Odontogenic Tumor

MalaCards organs/tissues related to Calcifying Epithelial Odontogenic Tumor:

42
Bone, Eye, Breast, Prostate

Publications for Calcifying Epithelial Odontogenic Tumor

Articles related to Calcifying Epithelial Odontogenic Tumor:

(show top 50) (show all 167)
# Title Authors Year
1
Surgical management of a large calcifying epithelial odontogenic tumor in the maxilla: A case report. ( 30981981 )
2019
2
Multiple calcifying epithelial odontogenic tumor: case report and review of the literature. ( 31078504 )
2019
3
Calcifying Epithelial Odontogenic (Pindborg) Tumor in a Child: A Case Report and Literature Review. ( 30771214 )
2019
4
Microcystic Calcifying Epithelial Odontogenic Tumor. ( 29164474 )
2018
5
Peripheral variant of calcifying epithelial odontogenic tumor with clear cell changes: An enigma. ( 29676382 )
2018
6
Peripheral clear cell variant of calcifying epithelial odontogenic tumor devoid of calcification. ( 29695670 )
2018
7
Non-calcifying Langerhans Cell-Rich Variant of Calcifying Epithelial Odontogenic Tumor: A Distinct Entity with Predilection for Anterior Maxilla. ( 30109555 )
2018
8
What Is the Non-calcifying Langerhans Cell-Rich Variant of Calcifying Epithelial Odontogenic Tumor? ( 30284106 )
2018
9
Pindborg tumor: Pathology with special stains. ( 29676366 )
2018
10
Who Originally Described Pindborg Tumor? ( 30027385 )
2018
11
Clear Cell Variant of Calcifying Epithelial Odontogenic Tumor: A Case Report and Preliminary Immunohistochemical Study of the SHH Pathway. ( 27941562 )
2017
12
Non Calcifying Type of Calcifying Epithelial Odontogenic Tumor: An Unusual Case Report with Special Emphasis on Histogenesis of Calcifications. ( 28439170 )
2017
13
Calcifying epithelial odontogenic tumor: An updated analysis of 339 cases reported in the literature. ( 28601296 )
2017
14
Clear Cell Variant of Calcifying Epithelial Odontogenic Tumor: A Rare Clinical Entity. ( 28798004 )
2017
15
A unique case of clear cell variant of calcifying epithelial odontogenic tumor involving the maxilla. ( 28928785 )
2017
16
Pindborg tumor in the distal femur. ( 28409146 )
2017
17
Clear cell variant of intraosseous calcifying epithelial odontogenic tumor: a case report and review of the literature. ( 26953043 )
2016
18
Aggressive Calcifying Epithelial Odontogenic Tumor of the Maxillary Sinus with Extraosseous Oral Mucosal Involvement: A Case Report. ( 26989286 )
2016
19
Peripheral Clear Cell Variant of Calcifying Epithelial Odontogenic Tumor: Case Report and Review of the Literature. ( 27154023 )
2016
20
Maxillary calcifying epithelial odontogenic tumor with sinus and buccal vestibule extension: a case report and immunohistochemical study. ( 27871286 )
2016
21
Non-calcifying and Langerhans cell-rich variant of calcifying epithelial odontogenic tumor. ( 30894958 )
2016
22
Pindborg tumor. ( 27041911 )
2016
23
Pindborg Tumor Presenting as a Nasal Polyp: Immunohistology and Ultrastructural Features of a Rare Case, With Review of the Literature. ( 27098590 )
2016
24
Pigmented Pindborg tumor of the maxilla: A case report. ( 27721633 )
2016
25
A rare case of hybrid odontogenic tumor: Calcifying epithelial odontogenic tumor combined with ameloblastoma. ( 26604514 )
2015
26
Clear cell variant of calcifying epithelial odontogenic tumor: Case report with immunohistochemical findings. ( 25810830 )
2015
27
Noncalcifying variant of calcifying epithelial odontogenic tumor with Langerhans cells. ( 25997388 )
2015
28
Calcifying epithelial odontogenic tumor: report of a recurrent destructive case with review of literature. ( 26005457 )
2015
29
Treatment of calcifying epithelial odontogenic tumor/Pindborg tumor by a conservative surgical method. ( 26015736 )
2015
30
Cystic Variant of Calcifying Epithelial Odontogenic Tumor. ( 26167990 )
2015
31
Maxillary Calcifying Epithelial Odontogenic Tumor in a Siberian Tiger (Panthera tigris altaica). ( 26415389 )
2015
32
Intraosseous calcifying epithelial odontogenic (Pindborg) tumor: A rare entity. ( 26604515 )
2015
33
A clinicopathologic study on calcifying epithelial odontogenic tumor: with special reference to Langerhans cell variant. ( 24555881 )
2014
34
Calcifying epithelial odontogenic tumor, a rare presentation in children: two case reports. ( 24739915 )
2014
35
Calcifying epithelial odontogenic tumor: a clinico-radio-pathological dilemma. ( 24762511 )
2014
36
Clear cell variant of calcifying epithelial odontogenic tumor without calcification: a rarity. ( 24939279 )
2014
37
Current Concepts and Occurrence of Epithelial Odontogenic Tumors: II. Calcifying Epithelial Odontogenic Tumor Versus Ghost Cell Odontogenic Tumors Derived from Calcifying Odontogenic Cyst. ( 25013415 )
2014
38
Peripheral calcifying epithelial odontogenic tumor - Case report. ( 25737934 )
2014
39
Clear cell cystic variant of calcifying epithelial odontogenic tumor. ( 24081908 )
2014
40
Establishment and characterization of a primary calcifying epithelial odontogenic tumor cell population. ( 24118390 )
2014
41
Guided bone regeneration following surgical treatment of a rare variant of Pindborg tumor: a case report. ( 24739714 )
2014
42
Pindborg tumor arising in association with an impacted supernumerary tooth in the anterior maxilla. ( 25007464 )
2014
43
Calcifying epithelial odontogenic tumor. ( 24379981 )
2013
44
Giant pindborg tumor (calcifying epithelial odontogenic tumor): an unusual case report with radiologic-pathologic correlation. ( 24516774 )
2013
45
Clear cell variant of calcifying epithelial odontogenic tumor of maxilla: Report of a rare case. ( 24574681 )
2013
46
Calcifying epithelial odontogenic tumor: case report with immunohistochemical and ultrastructural study and review of the literature. ( 22868029 )
2013
47
Calcifying epithelial odontogenic tumor in anterior maxilla associated with a supernumerary tooth: a case report. ( 23487408 )
2013
48
Clear-cell variant of calcifying epithelial odontogenic tumor (Pindborg tumor) in the mandible. ( 23703711 )
2013
49
Calcifying epithelial odontogenic tumor (CEOT): a clinicopathologic and immunohistochemical study and comparison with dental follicles containing CEOT-like areas. ( 24237727 )
2013
50
Recurrent Pindborg tumor of the maxilla: a case report and review of the literature. ( 23460217 )
2013

Variations for Calcifying Epithelial Odontogenic Tumor

Expression for Calcifying Epithelial Odontogenic Tumor

Search GEO for disease gene expression data for Calcifying Epithelial Odontogenic Tumor.

Pathways for Calcifying Epithelial Odontogenic Tumor

GO Terms for Calcifying Epithelial Odontogenic Tumor

Cellular components related to Calcifying Epithelial Odontogenic Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nuclear matrix GO:0016363 8.62 KRT8 TP53

Biological processes related to Calcifying Epithelial Odontogenic Tumor according to GeneCards Suite gene sharing:

(show all 13)
# Name GO ID Score Top Affiliating Genes
1 negative regulation of transcription by RNA polymerase II GO:0000122 9.7 GLI2 PTCH1 TP53
2 positive regulation of transcription, DNA-templated GO:0045893 9.69 GLI2 PTCH1 TP53
3 cell proliferation GO:0008283 9.61 AMBN GLI2 TP53
4 smoothened signaling pathway GO:0007224 9.49 GLI2 PTCH1
5 pattern specification process GO:0007389 9.48 GLI2 PTCH1
6 odontogenesis of dentin-containing tooth GO:0042475 9.46 AMBN GLI2
7 dorsal/ventral pattern formation GO:0009953 9.4 GLI2 PTCH1
8 mammary gland development GO:0030879 9.37 GLI2 PTCH1
9 regulation of smoothened signaling pathway GO:0008589 9.32 GLI2 PTCH1
10 spinal cord motor neuron differentiation GO:0021522 9.26 GLI2 PTCH1
11 dorsal/ventral neural tube patterning GO:0021904 9.16 GLI2 PTCH1
12 smoothened signaling pathway involved in dorsal/ventral neural tube patterning GO:0060831 8.96 GLI2 PTCH1
13 mammary gland duct morphogenesis GO:0060603 8.62 GLI2 PTCH1

Molecular functions related to Calcifying Epithelial Odontogenic Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 promoter-specific chromatin binding GO:1990841 8.62 GLI2 TP53

Sources for Calcifying Epithelial Odontogenic Tumor

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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