CEOT
MCID: CLC010
MIFTS: 30

Calcifying Epithelial Odontogenic Tumor (CEOT)

Categories: Rare diseases

Aliases & Classifications for Calcifying Epithelial Odontogenic Tumor

MalaCards integrated aliases for Calcifying Epithelial Odontogenic Tumor:

Name: Calcifying Epithelial Odontogenic Tumor 52 71
Pindborg Tumor 52
Ceot 52

Classifications:



External Ids:

UMLS 71 C0334574

Summaries for Calcifying Epithelial Odontogenic Tumor

MalaCards based summary : Calcifying Epithelial Odontogenic Tumor, also known as pindborg tumor, is related to keratocystic odontogenic tumor and ameloblastoma. An important gene associated with Calcifying Epithelial Odontogenic Tumor is AMBN (Ameloblastin), and among its related pathways/superpathways are Pathways in cancer and Wnt Signaling Pathways: beta-Catenin-dependent Wnt Signaling. Affiliated tissues include breast, thyroid and skin, and related phenotypes are craniofacial and digestive/alimentary

Wikipedia : 74 The calcifying epithelial odontogenic tumor (CEOT), also known as a Pindborg tumor, is an odontogenic... more...

Related Diseases for Calcifying Epithelial Odontogenic Tumor

Diseases related to Calcifying Epithelial Odontogenic Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 88)
# Related Disease Score Top Affiliating Genes
1 keratocystic odontogenic tumor 29.8 TP53 PTCH1
2 ameloblastoma 29.5 TP53 PTCH1 KRT8 AMBN
3 basal cell nevus syndrome 29.5 TP53 PTCH1 GLI2
4 basal cell carcinoma 28.8 TP53 PTCH1 KRT8 GLI2
5 rare tumor 10.4
6 rapidly involuting congenital hemangioma 10.3
7 persistent idiopathic facial pain 10.1
8 tuberous sclerosis 1 10.1
9 myeloma, multiple 10.1
10 osteogenic sarcoma 10.1
11 fibroma 10.1
12 osteoblastoma 10.1
13 tuberous sclerosis 10.1
14 root resorption 10.1
15 acinar cell carcinoma 10.1
16 clear cell adenocarcinoma 10.1
17 mucoepidermoid carcinoma 10.1
18 myoepithelial carcinoma 10.1
19 epithelial-myoepithelial carcinoma 10.1
20 hard palate cancer 10.1
21 nasal cavity neoplasm 10.1
22 exophthalmos 10.1
23 stomatitis 10.1
24 ulcerative stomatitis 10.1
25 47,xyy 10.1
26 pyogenic granuloma 10.1
27 posttransplant acute limbic encephalitis 10.1
28 rare odontogenic tumor 10.1
29 keratinizing squamous cell carcinoma 10.0 TP53 KRT8
30 epidermal appendage tumor 9.9 TP53 KRT8
31 sweat gland neoplasm 9.9 TP53 KRT8
32 pleomorphic carcinoma 9.9 TP53 KRT8
33 basaloid squamous cell carcinoma 9.9 TP53 KRT8
34 thoracic benign neoplasm 9.9 TP53 KRT8
35 breast benign neoplasm 9.9 TP53 KRT8
36 sweat gland cancer 9.9 TP53 KRT8
37 luminal breast carcinoma 9.9 TP53 KRT8
38 breast fibroadenoma 9.9 TP53 KRT8
39 pre-malignant neoplasm 9.9 TP53 KRT8
40 adenosquamous carcinoma 9.9 TP53 KRT8
41 small cell carcinoma 9.9 TP53 KRT8
42 in situ carcinoma 9.9 TP53 KRT8
43 breast carcinoma in situ 9.8 TP53 KRT8
44 merkel cell carcinoma 9.8 TP53 KRT8
45 angiosarcoma 9.8 TP53 KRT8
46 holoprosencephaly, recurrent infections, and monocytosis 9.8 PTCH1 GLI2
47 basosquamous carcinoma 9.8 TP53 PTCH1
48 nodular medulloblastoma 9.8 PTCH1 GLI2
49 holoprosencephaly 9 9.8 PTCH1 GLI2
50 midline interhemispheric variant of holoprosencephaly 9.8 PTCH1 GLI2

Graphical network of the top 20 diseases related to Calcifying Epithelial Odontogenic Tumor:



Diseases related to Calcifying Epithelial Odontogenic Tumor

Symptoms & Phenotypes for Calcifying Epithelial Odontogenic Tumor

MGI Mouse Phenotypes related to Calcifying Epithelial Odontogenic Tumor:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 craniofacial MP:0005382 9.62 AMBN GLI2 PTCH1 TP53
2 digestive/alimentary MP:0005381 9.56 GLI2 KRT8 PTCH1 TP53
3 embryo MP:0005380 9.46 GLI2 KRT8 PTCH1 TP53
4 growth/size/body region MP:0005378 9.35 AMBN GLI2 KRT8 PTCH1 TP53
5 hearing/vestibular/ear MP:0005377 8.92 GLI2 KRT8 PTCH1 TP53

Drugs & Therapeutics for Calcifying Epithelial Odontogenic Tumor

Search Clinical Trials , NIH Clinical Center for Calcifying Epithelial Odontogenic Tumor

Genetic Tests for Calcifying Epithelial Odontogenic Tumor

Anatomical Context for Calcifying Epithelial Odontogenic Tumor

MalaCards organs/tissues related to Calcifying Epithelial Odontogenic Tumor:

40
Breast, Thyroid, Skin, Bone, Salivary Gland, Eye, Cerebellum

Publications for Calcifying Epithelial Odontogenic Tumor

Articles related to Calcifying Epithelial Odontogenic Tumor:

(show top 50) (show all 258)
# Title Authors PMID Year
1
p16INK4a as a proliferation marker unrelated to HPV expression in odontogenic cysts and tumors. 61
31680334 2020
2
A Rare Case of an Aggressive Clear Cell Variant of Calcifying Epithelial Odontogenic Tumor in the Posterior Maxilla. 61
31986944 2020
3
Nuclear atypia in Pindborg tumor: An unexplored phenomenon of a well recognized entity. 61
31767420 2020
4
Non-calcifying Langerhans Cell-Rich Variant of Calcifying Epithelial Odontogenic Tumor: A Distinct Entity with Predilection for Anterior Maxilla. 61
30109555 2019
5
Calcifying Epithelial Odontogenic (Pindborg) Tumor in a Child: A Case Report and Literature Review. 61
30771214 2019
6
Who Originally Described Pindborg Tumor? 61
30027385 2019
7
Multiple calcifying epithelial odontogenic tumor: case report and review of the literature. 61
31078504 2019
8
Clinical, radiological and histological features of an unique case of calcifying epithelial odontogenic tumor. 61
31942142 2019
9
What Is the Non-calcifying Langerhans Cell-Rich Variant of Calcifying Epithelial Odontogenic Tumor? 61
30284106 2019
10
Synchronous Calcifying Epithelial Odontogenic Tumor: Case Report and Analysis of the 5 Cases in the Literature. 61
31352628 2019
11
Surgical management of a large calcifying epithelial odontogenic tumor in the maxilla: A case report. 61
30981981 2019
12
Microcystic Calcifying Epithelial Odontogenic Tumor. 61
29164474 2018
13
Benign and malignant odontogenic neoplasms of the jaws show a concordant nondiscriminatory p63/p40 positive immunophenotype. 61
30309829 2018
14
A clinicopathologic study on central odontogenic fibroma: with special reference to amyloid variant. 61
30291007 2018
15
A radiolucent lesion presenting calcification histopathologically: a classical case of CEOT. 61
30476388 2018
16
Clinical and Histopathological Analysis of Odontogenic Tumors in Institution-A 10 Years Retrospective Study. 61
30498188 2018
17
Peripheral clear cell variant of calcifying epithelial odontogenic tumor devoid of calcification. 61
29695670 2018
18
Peripheral variant of calcifying epithelial odontogenic tumor with clear cell changes: An enigma. 61
29676382 2018
19
Pindborg tumor: Pathology with special stains. 61
29676366 2018
20
Ghost cell odontogenic carcinoma with suspected cholesterol granuloma of the maxillary sinus in a patient treated with combined modality therapy: A case report and the review of literature. 61
29443742 2018
21
A Combined Epithelial Odontogenic Tumor? A 7-Year Follow-Up Case. 61
27817004 2017
22
Clear Cell Variant of Calcifying Epithelial Odontogenic Tumor: A Case Report and Preliminary Immunohistochemical Study of the SHH Pathway. 61
27941562 2017
23
Calcifying epithelial odontogenic tumor: An updated analysis of 339 cases reported in the literature. 61
28601296 2017
24
A unique case of clear cell variant of calcifying epithelial odontogenic tumor involving the maxilla. 61
28928785 2017
25
Non Calcifying Type of Calcifying Epithelial Odontogenic Tumor: An Unusual Case Report with Special Emphasis on Histogenesis of Calcifications. 61
28439170 2017
26
Clear Cell Variant of Calcifying Epithelial Odontogenic Tumor: A Rare Clinical Entity. 61
28798004 2017
27
Odontogenic Cysts and Neoplasms. 61
28153133 2017
28
Pindborg tumor in the distal femur. 61
28409146 2017
29
Peripheral Clear Cell Variant of Calcifying Epithelial Odontogenic Tumor: Case Report and Review of the Literature. 61
27154023 2016
30
Maxillary calcifying epithelial odontogenic tumor with sinus and buccal vestibule extension: a case report and immunohistochemical study. 61
27871286 2016
31
Clear cell variant of intraosseous calcifying epithelial odontogenic tumor: a case report and review of the literature. 61
26953043 2016
32
Pigmented Pindborg tumor of the maxilla: A case report. 61
27721633 2016
33
Mandibular intraosseous pseudocarcinomatous hyperplasia: a case report. 61
27680099 2016
34
Pindborg Tumor Presenting as a Nasal Polyp: Immunohistology and Ultrastructural Features of a Rare Case, With Review of the Literature. 61
27098590 2016
35
Maxillary Calcifying Epithelial Odontogenic Tumour. 61
27935922 2016
36
Non-calcifying and Langerhans cell-rich variant of calcifying epithelial odontogenic tumor. 61
30894958 2016
37
Kallikrein 4 and matrix metalloproteinase-20 immunoexpression in malignant, benign and infiltrative odontogenic tumors. 61
27601817 2016
38
Aggressive Calcifying Epithelial Odontogenic Tumor of the Maxillary Sinus with Extraosseous Oral Mucosal Involvement: A Case Report. 61
26989286 2016
39
[Calcifying epithelial odontogenic tumor: two cases report]. 61
27266209 2016
40
Pindborg tumor. 61
27041911 2016
41
Report of Two Cases of Combined Odontogenic Tumors: Ameloblastoma with Odontogenic Keratocyst and Ameloblastic Fibroma with Calcifying Odontogenic Cyst. 61
25552434 2015
42
Noncalcifying variant of calcifying epithelial odontogenic tumor with Langerhans cells. 61
25997388 2015
43
Cystic Variant of Calcifying Epithelial Odontogenic Tumor. 61
26167990 2015
44
A rare case of hybrid odontogenic tumor: Calcifying epithelial odontogenic tumor combined with ameloblastoma. 61
26604514 2015
45
Intraosseous calcifying epithelial odontogenic (Pindborg) tumor: A rare entity. 61
26604515 2015
46
Treatment of calcifying epithelial odontogenic tumor/Pindborg tumor by a conservative surgical method. 61
26015736 2015
47
Clear cell variant of calcifying epithelial odontogenic tumor: Case report with immunohistochemical findings. 61
25810830 2015
48
Maxillary Calcifying Epithelial Odontogenic Tumor in a Siberian Tiger (Panthera tigris altaica). 61
26415389 2015
49
Calcifying epithelial odontogenic tumor: report of a recurrent destructive case with review of literature. 61
26005457 2015
50
[CEOT - Calcified anomalies in dental X-ray. A case-based review of differential diagnoses in radiopaque lesions in maxilla and mandible]. 61
26168688 2015

Variations for Calcifying Epithelial Odontogenic Tumor

Expression for Calcifying Epithelial Odontogenic Tumor

Search GEO for disease gene expression data for Calcifying Epithelial Odontogenic Tumor.

Pathways for Calcifying Epithelial Odontogenic Tumor

GO Terms for Calcifying Epithelial Odontogenic Tumor

Cellular components related to Calcifying Epithelial Odontogenic Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nuclear matrix GO:0016363 8.62 TP53 KRT8

Biological processes related to Calcifying Epithelial Odontogenic Tumor according to GeneCards Suite gene sharing:

(show all 14)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of transcription, DNA-templated GO:0045893 9.71 TP53 PTCH1 GLI2
2 smoothened signaling pathway GO:0007224 9.52 PTCH1 GLI2
3 odontogenesis of dentin-containing tooth GO:0042475 9.51 GLI2 AMBN
4 in utero embryonic development GO:0001701 9.5 TP53 PTCH1 GLI2
5 pattern specification process GO:0007389 9.49 PTCH1 GLI2
6 response to retinoic acid GO:0032526 9.48 TP53 PTCH1
7 dorsal/ventral pattern formation GO:0009953 9.46 PTCH1 GLI2
8 embryonic organ development GO:0048568 9.43 TP53 PTCH1
9 regulation of cell proliferation GO:0042127 9.43 TP53 PTCH1 AMBN
10 mammary gland development GO:0030879 9.4 PTCH1 GLI2
11 spinal cord motor neuron differentiation GO:0021522 9.37 PTCH1 GLI2
12 dorsal/ventral neural tube patterning GO:0021904 9.16 PTCH1 GLI2
13 smoothened signaling pathway involved in dorsal/ventral neural tube patterning GO:0060831 8.96 PTCH1 GLI2
14 mammary gland duct morphogenesis GO:0060603 8.62 PTCH1 GLI2

Molecular functions related to Calcifying Epithelial Odontogenic Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 promoter-specific chromatin binding GO:1990841 8.62 TP53 GLI2

Sources for Calcifying Epithelial Odontogenic Tumor

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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