MCID: CLC010
MIFTS: 31

Calcifying Epithelial Odontogenic Tumor

Categories: Rare diseases

Aliases & Classifications for Calcifying Epithelial Odontogenic Tumor

MalaCards integrated aliases for Calcifying Epithelial Odontogenic Tumor:

Name: Calcifying Epithelial Odontogenic Tumor 53 73
Pindborg Tumor 53
Ceot 53

Classifications:



External Ids:

UMLS 73 C0334574

Summaries for Calcifying Epithelial Odontogenic Tumor

MalaCards based summary : Calcifying Epithelial Odontogenic Tumor, also known as pindborg tumor, is related to ameloblastoma and gingivitis. An important gene associated with Calcifying Epithelial Odontogenic Tumor is AMBN (Ameloblastin), and among its related pathways/superpathways are Pathways in cancer and Hedgehog Pathway. Related phenotypes are craniofacial and digestive/alimentary

Wikipedia : 76 The calcifying epithelial odontogenic tumor, also known as a Pindborg tumor or CEOT, is an odontogenic... more...

Related Diseases for Calcifying Epithelial Odontogenic Tumor

Diseases related to Calcifying Epithelial Odontogenic Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 43)
# Related Disease Score Top Affiliating Genes
1 ameloblastoma 29.4 AMBN KRT8 PTCH1
2 gingivitis 10.1
3 pleomorphic carcinoma 10.0 KRT8 TP53
4 prostate squamous cell carcinoma 10.0 KRT8 TP53
5 basaloid squamous cell carcinoma 10.0 KRT8 TP53
6 tuberous sclerosis 1 9.9
7 myeloma, multiple 9.9
8 osteoblastoma 9.9
9 mucositis 9.9
10 tuberous sclerosis 9.9
11 stomatitis 9.9
12 ulcerative stomatitis 9.9
13 sweat gland cancer 9.9 KRT8 TP53
14 adenosquamous carcinoma 9.9 KRT8 TP53
15 cervical squamous cell carcinoma 9.9 KRT8 TP53
16 ductal carcinoma in situ 9.9 KRT8 TP53
17 merkel cell carcinoma 9.8 KRT8 TP53
18 holoprosencephaly, recurrent infections, and monocytosis 9.8 GLI2 PTCH1
19 septopreoptic holoprosencephaly 9.8 GLI2 PTCH1
20 midline interhemispheric variant of holoprosencephaly 9.8 GLI2 PTCH1
21 nodular medulloblastoma 9.8 GLI2 PTCH1
22 alobar holoprosencephaly 9.8 GLI2 PTCH1
23 lobar holoprosencephaly 9.8 GLI2 PTCH1
24 microform holoprosencephaly 9.8 GLI2 PTCH1
25 semilobar holoprosencephaly 9.8 GLI2 PTCH1
26 cerebellar liponeurocytoma 9.7 PTCH1 TP53
27 keratocystic odontogenic tumor 9.7 PTCH1 TP53
28 adult medulloblastoma 9.7 PTCH1 TP53
29 bardet-biedl syndrome 17 9.7 GLI2 PTCH1
30 breast ductal carcinoma 9.7 KRT8 TP53
31 brooke-spiegler syndrome 9.7 KRT8 PTCH1
32 transitional cell carcinoma 9.7 KRT8 TP53
33 basal cell nevus syndrome 9.6 GLI2 PTCH1
34 papilloma 9.6 KRT8 TP53
35 nervous system cancer 9.6 PTCH1 TP53
36 autosomal genetic disease 9.6 PTCH1 TP53
37 endocrine gland cancer 9.5 PTCH1 TP53
38 xeroderma pigmentosum, variant type 9.2 PTCH1 TP53
39 infratentorial cancer 9.2 GLI2 PTCH1 TP53
40 integumentary system cancer 9.2 GLI2 PTCH1 TP53
41 medulloblastoma 9.1 GLI2 PTCH1 TP53
42 holoprosencephaly 9.0 GLI2 PTCH1
43 basal cell carcinoma 8.5 GLI2 KRT8 PTCH1 TP53

Graphical network of the top 20 diseases related to Calcifying Epithelial Odontogenic Tumor:



Diseases related to Calcifying Epithelial Odontogenic Tumor

Symptoms & Phenotypes for Calcifying Epithelial Odontogenic Tumor

MGI Mouse Phenotypes related to Calcifying Epithelial Odontogenic Tumor:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 craniofacial MP:0005382 9.71 TP53 AMBN GLI2 PTCH1
2 digestive/alimentary MP:0005381 9.67 TP53 GLI2 KRT8 PTCH1
3 growth/size/body region MP:0005378 9.65 PTCH1 TP53 AMBN GLI2 KRT8
4 embryo MP:0005380 9.62 PTCH1 TP53 GLI2 KRT8
5 hearing/vestibular/ear MP:0005377 9.46 TP53 GLI2 KRT8 PTCH1
6 reproductive system MP:0005389 9.26 PTCH1 TP53 GLI2 KRT8
7 skeleton MP:0005390 8.92 PTCH1 TP53 AMBN GLI2

Drugs & Therapeutics for Calcifying Epithelial Odontogenic Tumor

Search Clinical Trials , NIH Clinical Center for Calcifying Epithelial Odontogenic Tumor

Genetic Tests for Calcifying Epithelial Odontogenic Tumor

Anatomical Context for Calcifying Epithelial Odontogenic Tumor

Publications for Calcifying Epithelial Odontogenic Tumor

Articles related to Calcifying Epithelial Odontogenic Tumor:

(show top 50) (show all 132)
# Title Authors Year
1
Peripheral clear cell variant of calcifying epithelial odontogenic tumor devoid of calcification. ( 29695670 )
2018
2
Peripheral variant of calcifying epithelial odontogenic tumor with clear cell changes: An enigma. ( 29676382 )
2018
3
Clear Cell Variant of Calcifying Epithelial Odontogenic Tumor: A Rare Clinical Entity. ( 28798004 )
2017
4
Microcystic Calcifying Epithelial Odontogenic Tumor. ( 29164474 )
2017
5
A unique case of clear cell variant of calcifying epithelial odontogenic tumor involving the maxilla. ( 28928785 )
2017
6
Non Calcifying Type of Calcifying Epithelial Odontogenic Tumor: An Unusual Case Report with Special Emphasis on Histogenesis of Calcifications. ( 28439170 )
2017
7
Calcifying epithelial odontogenic tumor: An updated analysis of 339 cases reported in the literature. ( 28601296 )
2017
8
Maxillary calcifying epithelial odontogenic tumor with sinus and buccal vestibule extension: a case report and immunohistochemical study. ( 27871286 )
2016
9
Aggressive Calcifying Epithelial Odontogenic Tumor of the Maxillary Sinus with Extraosseous Oral Mucosal Involvement: A Case Report. ( 26989286 )
2016
10
Peripheral Clear Cell Variant of Calcifying Epithelial Odontogenic Tumor: Case Report and Review of the Literature. ( 27154023 )
2016
11
Clear Cell Variant of Calcifying Epithelial Odontogenic Tumor: A Case Report and Preliminary Immunohistochemical Study of the SHH Pathway. ( 27941562 )
2016
12
Clear cell variant of intraosseous calcifying epithelial odontogenic tumor: a case report and review of the literature. ( 26953043 )
2016
13
Maxillary Calcifying Epithelial Odontogenic Tumor in a Siberian Tiger (Panthera tigris altaica). ( 26415389 )
2015
14
Treatment of calcifying epithelial odontogenic tumor/Pindborg tumor by a conservative surgical method. ( 26015736 )
2015
15
Noncalcifying variant of calcifying epithelial odontogenic tumor with Langerhans cells. ( 25997388 )
2015
16
Clear cell variant of calcifying epithelial odontogenic tumor: Case report with immunohistochemical findings. ( 25810830 )
2015
17
Calcifying epithelial odontogenic tumor: report of a recurrent destructive case with review of literature. ( 26005457 )
2015
18
A rare case of hybrid odontogenic tumor: Calcifying epithelial odontogenic tumor combined with ameloblastoma. ( 26604514 )
2015
19
Cystic Variant of Calcifying Epithelial Odontogenic Tumor. ( 26167990 )
2015
20
Clear cell variant of calcifying epithelial odontogenic tumor without calcification: a rarity. ( 24939279 )
2014
21
Calcifying epithelial odontogenic tumor: a clinico-radio-pathological dilemma. ( 24762511 )
2014
22
Current Concepts and Occurrence of Epithelial Odontogenic Tumors: II. Calcifying Epithelial Odontogenic Tumor Versus Ghost Cell Odontogenic Tumors Derived from Calcifying Odontogenic Cyst. ( 25013415 )
2014
23
A clinicopathologic study on calcifying epithelial odontogenic tumor: with special reference to Langerhans cell variant. ( 24555881 )
2014
24
Calcifying epithelial odontogenic tumor, a rare presentation in children: two case reports. ( 24739915 )
2014
25
Giant pindborg tumor (calcifying epithelial odontogenic tumor): an unusual case report with radiologic-pathologic correlation. ( 24516774 )
2013
26
Calcifying epithelial odontogenic tumor (CEOT): a clinicopathologic and immunohistochemical study and comparison with dental follicles containing CEOT-like areas. ( 24237727 )
2013
27
Clear cell Cystic Variant of Calcifying Epithelial Odontogenic Tumor. ( 24081908 )
2013
28
Clear-cell variant of calcifying epithelial odontogenic tumor (Pindborg tumor) in the mandible. ( 23703711 )
2013
29
Establishment and characterization of a primary calcifying epithelial odontogenic tumor cell population. ( 24118390 )
2013
30
Calcifying epithelial odontogenic tumor. ( 24379981 )
2013
31
Calcifying epithelial odontogenic tumor in anterior maxilla associated with a supernumerary tooth: a case report. ( 23487408 )
2013
32
Calcifying epithelial odontogenic tumor: case report with immunohistochemical and ultrastructural study and review of the literature. ( 22868029 )
2013
33
Clear cell variant of calcifying epithelial odontogenic tumor of maxilla: Report of a rare case. ( 24574681 )
2013
34
CT and MR imaging features of a case of calcifying epithelial odontogenic tumor. ( 23198374 )
2012
35
Cystic variant of calcifying epithelial odontogenic tumor. ( 22522953 )
2012
36
Oral and maxillofacial pathology. Case of the month. Calcifying epithelial odontogenic tumor (Pindborg tumor). ( 23311025 )
2012
37
Calcifying epithelial odontogenic tumor (Pindborg tumor) without calcification: A rare entity. ( 22434947 )
2012
38
Calcifying epithelial odontogenic tumor of the maxilla (Pindborg tumor). ( 23397788 )
2012
39
Calcifying epithelial odontogenic tumor (Pindborg tumor). ( 22639521 )
2011
40
Calcifying epithelial odontogenic tumor (Pindborg tumor). ( 21327587 )
2011
41
Calcifying epithelial odontogenic tumor: a case report. ( 21986256 )
2011
42
Large calcifying epithelial odontogenic tumor with extension into the maxillary sinus: a case report. ( 21613030 )
2011
43
Diagnostic discussion. Calcifying epithelial odontogenic tumor or Pindborg tumor. ( 21314038 )
2010
44
Mixed odontogenic tumor: ameloblastoma and calcifying epithelial odontogenic tumor. ( 20090240 )
2010
45
Malignant transformation of calcifying epithelial odontogenic tumor is associated with the loss of p53 transcriptional activity: a case report with review of the literature. ( 20542620 )
2010
46
Involvement of PTCH1 mutations in the calcifying epithelial odontogenic tumor. ( 20371205 )
2010
47
Calcifying epithelial odontogenic tumor of the maxilla with ulcerative stomatitis: a case report. ( 18790551 )
2009
48
Clear cell variant of calcifying epithelial odontogenic tumor: is it locally aggressive? ( 19070770 )
2009
49
Mutation of ameloblastin gene in calcifying epithelial odontogenic tumor. ( 19661317 )
2009
50
Peripheral clear cell variant of calcifying epithelial odontogenic tumor affecting 2 sites: report of a case. ( 19157927 )
2009

Variations for Calcifying Epithelial Odontogenic Tumor

Expression for Calcifying Epithelial Odontogenic Tumor

Search GEO for disease gene expression data for Calcifying Epithelial Odontogenic Tumor.

Pathways for Calcifying Epithelial Odontogenic Tumor

GO Terms for Calcifying Epithelial Odontogenic Tumor

Cellular components related to Calcifying Epithelial Odontogenic Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nuclear matrix GO:0016363 8.62 KRT8 TP53

Biological processes related to Calcifying Epithelial Odontogenic Tumor according to GeneCards Suite gene sharing:

(show all 15)
# Name GO ID Score Top Affiliating Genes
1 negative regulation of transcription by RNA polymerase II GO:0000122 9.72 GLI2 PTCH1 TP53
2 positive regulation of transcription, DNA-templated GO:0045893 9.71 GLI2 PTCH1 TP53
3 cell proliferation GO:0008283 9.63 AMBN GLI2 TP53
4 response to mechanical stimulus GO:0009612 9.52 GLI2 PTCH1
5 smoothened signaling pathway GO:0007224 9.51 GLI2 PTCH1
6 odontogenesis of dentin-containing tooth GO:0042475 9.49 AMBN GLI2
7 pattern specification process GO:0007389 9.48 GLI2 PTCH1
8 dorsal/ventral pattern formation GO:0009953 9.43 GLI2 PTCH1
9 mammary gland development GO:0030879 9.4 GLI2 PTCH1
10 regulation of smoothened signaling pathway GO:0008589 9.37 GLI2 PTCH1
11 spinal cord motor neuron differentiation GO:0021522 9.32 GLI2 PTCH1
12 prostate gland development GO:0030850 9.26 GLI2 PTCH1
13 dorsal/ventral neural tube patterning GO:0021904 9.16 GLI2 PTCH1
14 smoothened signaling pathway involved in dorsal/ventral neural tube patterning GO:0060831 8.96 GLI2 PTCH1
15 mammary gland duct morphogenesis GO:0060603 8.62 GLI2 PTCH1

Molecular functions related to Calcifying Epithelial Odontogenic Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 promoter-specific chromatin binding GO:1990841 8.62 GLI2 TP53

Sources for Calcifying Epithelial Odontogenic Tumor

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
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28 GO
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31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
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44 MeSH
45 MESH via Orphanet
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49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
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62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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