Drugs for Calciphylaxis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):
(show all 32)
# |
|
Name |
Status |
Phase |
Clinical Trials |
Cas Number |
PubChem Id |
1 |
|
Magnesium citrate |
Approved |
Phase 3 |
|
3344-18-1 |
|
Synonyms:
Magnesium citrate
Magnesium dicitrate
|
Trimagnesium citrate
Trimagnesium dicitrate
|
|
2 |
|
Phylloquinone |
Approved, Investigational |
Phase 3 |
|
84-80-0 |
5284607 |
Synonyms:
(2S)-2-(Henicosanoyloxy)-3-(tridecanoyloxy)propyl (7Z,10Z,19Z)-docosa-4,7,10,13,16,19-hexaenoic acid
2',3'-trans-Vitamin K1
2’,3’-trans-vitamin K1
2-Methyl-3-(3,7,11,15-tetramethyl-2-hexadecenyl)-1,4-naphthalenedione
2-Methyl-3-[(2E)-3,7,11,15-tetramethyl-2-hexadecenyl]naphthoquinone
2-METHYL-3-[(2E)-3,7,11,15-TETRAMETHYLHEXADEC-2-EN-1-YL]-1,4-DIHYDRONAPHTHALENE-1,4-DIONE
2-METHYL-3-[(2E,7R,11R)-3,7,11,15-TETRAMETHYLHEXADEC-2-EN-1-YL]NAPHTHALENE-1,4-DIONE
2-methyl-3-[(E,7R,11R)-3,7,11,15-tetramethylhexadec-2-enyl]naphthalene-1,4-dione
2-METHYL-3-PHYTHYL-1,4-NAPHTHOCHINON
2-Methyl-3-phytyl-1,4-naphthochinon
2-Methyl-3-phytyl-1,4-naphthoquinone
2-METHYL-3-PHYTYL-1,4-NAPTHOQUINONE
3-Phytylmenadione
alpha-Phylloquinone
ANTIHEMORRHAGIC VITAMIN
a-Phylloquinone
AQUA MEPHYTON
AQUA-MEPHYTIN
Aquamephyton
COMBINAL K1
Fitomenadiona
FITOMENADIONE
KANAVIT
KATIV N
KEPHTON
KINADION
K-JECT
|
Konakion
KONAKION MM
KONAKION MM PAED
MEPHYTON
MONODION
MONO-KAY
NEOKAY
NSC-270681
ORAKAY
Phyllochinon
Phyllochinonum
Phyllohydroquinone
Phylloquinone
PHYLLOQUINONE E-FORM
PHYTHYL-MENADION
Phytomenadione
Phytomenadionum
Phytonadione
Phytonadionum
Phytylmenadione
SYNTHEX P
trans-Phylloquinone
VITAMIN K
Vitamin K 1
Vitamin K hydroquinone (phylloquinone)
Vitamin K1
Α-phylloquinone
|
|
3 |
|
Sodium citrate |
Approved, Investigational |
Phase 3 |
|
68-04-2 |
23431961 |
Synonyms:
Anhydrous sodium citrate
Anhydrous trisodium citrate
Citric acid, trisodium salt
Natrii citras
Natrocitral
Sodium citrate anhydrous
Sodium citrate, anhydrous
|
Sodium citrate,anhydrous
Sodium citric acid
Trisodium 2-hydroxypropane-1,2,3-tricarboxylate
trisodium citrate anhydrous
Trisodium citrate, anhydrous
Trisodium-citrate
|
|
4 |
|
Menadione |
Approved, Nutraceutical |
Phase 3 |
|
58-27-5 |
4055 |
Synonyms:
2-METHYL-1,4-DIHYDRONAPHTHALENE-1,4-DIONE
2-Methyl-1,4-naftochinon
2-Methyl-1,4-naphthalendione
2-Methyl-1,4-naphthalenedione
2-Methyl-1,4-naphthochinon
2-Methyl-1,4-naphthodione
2-Methyl-1,4-naphthoquinone
2-Methylnaphthoquinone
3-Methyl-1,4-naphthoquinone
Aquakay
Aquinone
Bisulfite, menadione
Bisulfite, menadione sodium
Hemodal
Juva-K
Kaergona
Kanone
Kappaxan
Kappaxin
Karcon
Kareon
Kativ-g
Kayklot
Kaykot
Kaynone
Kayquinone
Kipca
Kipca-oil soluble
Klottone
Koaxin
Kolklot
|
K-Thrombyl
K-Vitan
Menadion
MENADIONE
Menadione bisulfite
Menadione sodium bisulfite
Menadione sodium bisulfite, trihydrate
Menaphthene
Menaphthon
Menaphthone
Menaphtone
Menaquinone
Menaquinone O
Mitenon
Mitenone
MNQ
NSC-4170
Panosine
Prokayvit
Sodium bisulfite, menadione
Synkay
Thyloquinone
Vicasol
Vikasol
Vitamin K 3
Vitamin K0
Vitamin K2
Vitamin K3
Vitamin K3 sodium bisulfite
Vitamin K3: 1,4-dihydro-1,4-dioxo-2-methylnaphthalene
|
|
5 |
|
Citric acid |
Approved, Nutraceutical, Vet_approved |
Phase 3 |
|
77-92-9 |
311 |
Synonyms:
2-hydroxy-1,2,3-propanetricarboxyic acid
2-Hydroxy-1,2,3-propanetricarboxylate
2-Hydroxy-1,2,3-propanetricarboxylic acid
2-Hydroxytricarballylate
2-Hydroxytricarballylic acid
3-Carboxy-3-hydroxypentane-1,5-dioate
3-Carboxy-3-hydroxypentane-1,5-dioic acid
Acid monohydrate, citric
ácido cítrico
Acidum citricum
Aciletten
Anhydrous citrate
Anhydrous citric acid
beta-Hydroxytricarballylate
beta-Hydroxytricarballylic acid
Chemfill
Citraclean
Citrate
Citrate anhydrous
Citretten
CITRIC ACID
Citric acid anhydrous
CITRIC ACID HYDRATE
Citric acid monoglyceride
|
Citric acid monohydrate
Citric acid, anhydrous
Citric acid,anhydrous
Citro
Citronensaeure
Citronensäure
e 330
e330
E-330
FEMA NO. 2306
H3Cit
Hydrocerol a
INS NO.330
INS-330
Kyselina citronova
Monohydrate, citric acid
NSC-112226
NSC-30279
NSC-626579
Suby g
Uralyt u
UROLOGIC G
Uro-trainer
|
|
6 |
|
Menaquinone |
Investigational |
Phase 3 |
|
1182-68-9 |
|
7 |
|
Cathartics |
|
Phase 3 |
|
|
|
8 |
|
Vitamins |
|
Phase 3 |
|
|
|
9 |
|
Vitamin K 1 |
|
Phase 3 |
|
|
|
10 |
|
Vitamin K |
|
Phase 3 |
|
|
|
11 |
|
Laxatives |
|
Phase 3 |
|
|
|
12 |
|
Trace Elements |
|
Phase 3 |
|
|
|
13 |
|
Antifibrinolytic Agents |
|
Phase 3 |
|
|
|
14 |
|
Anticoagulants |
|
Phase 3 |
|
|
|
15 |
|
Hemostatics |
|
Phase 3 |
|
|
|
16 |
|
Gastrointestinal Agents |
|
Phase 3 |
|
|
|
17 |
|
Naphthoquinone |
|
Phase 3 |
|
|
|
Synonyms:
[1,4]Naphthoquinon
1,4-Dihydro-1,4-diketonaphthalene
1,4-Naphthalenedione
1,4-NAPHTHOQUINONE
1,4-NAPHTHO-QUINONE
1,4-NQ
alpha-Naphthoquinone
|
a-Naphthoquinone
NAPHTHALENE-1,4-DIONE
Naphthoquinone
NAPHTHOQUINONE 1
p-Naphthoquinone
Succivil
Α-naphthoquinone
|
|
18 |
|
Micronutrients |
|
Phase 3 |
|
|
|
19 |
|
Coagulants |
|
Phase 3 |
|
|
|
20 |
|
Citrate |
|
Phase 3 |
|
|
|
21 |
|
Calcium, Dietary |
|
Phase 3 |
|
|
|
22 |
|
Sodium thiosulfate |
|
Phase 3 |
|
|
|
Synonyms:
Anhydrous sodium thiosulfate
Anhydrous sodium thiosulfuric acid
Anhydrous sodium thiosulphate
Anhydrous sodium thiosulphuric acid
Disodium thiosulfate
Disodium thiosulfuric acid
Disodium thiosulphate
Disodium thiosulphuric acid
Pentahydrate OF sodium thiosulfate
Sodium hyposulfite
Sodium hyposulphite
Sodium oxide sulfide
Sodium oxide sulphide
|
Sodium thiosulfate (anhydrous)
Sodium thiosulfate anhydrous
Sodium thiosulfate pentahydrate
Sodium thiosulfuric acid
Sodium thiosulfuric acid (anhydrous)
Sodium thiosulphate
Sodium thiosulphate (anhydrous)
Sodium thiosulphuric acid
Sodium thiosulphuric acid (anhydrous)
Thiosulfate, disodium salt
Thiosulfuric acid, disodium salt
Thiosulphate, disodium salt
Thiosulphuric acid, disodium salt
|
|
23 |
|
Anti-Bacterial Agents |
|
Phase 3 |
|
|
|
24 |
|
Anti-Infective Agents |
|
Phase 3 |
|
|
|
25 |
|
Antidotes |
|
Phase 3 |
|
|
|
26 |
|
Antitubercular Agents |
|
Phase 3 |
|
|
|
27 |
|
Antioxidants |
|
Phase 3 |
|
|
|
28 |
|
Protective Agents |
|
Phase 3 |
|
|
|
29 |
|
Chelating Agents |
|
Phase 3 |
|
|
|
30 |
|
Pharmaceutical Solutions |
|
Phase 3 |
|
|
|
31 |
|
Calcium |
Nutraceutical |
Phase 3 |
|
7440-70-2 |
271 |
Synonyms:
Ca
Ca(2+)
Ca2+
Calcio
CALCIUM
Calcium element
|
CALCIUM ion
Calcium(2+)
Calcium, doubly charged positive ion
Calcium, elemental
Elemental calcium
Kalzium
|
|
32 |
|
Warfarin |
Approved |
|
|
81-81-2, 129-06-6 |
54678486 |
Synonyms:
(Phenyl-1 acetyl-2 ethyl) 3-hydroxy-4 coumarin
(Phenyl-1 acetyl-2 ethyl) 3-hydroxy-4 coumarine
(S)-4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone
1-(4'-Hydroxy-3'-coumarinyl)-1-phenyl-3-butanone
200 Coumarin
3-(1'-Phenyl-2'-acetylethyl)-4-hydroxycoumarin
3-(Acetonylbenzyl)-4-hydroxycoumarin
3-(alpha-Acetonylbenzyl)-4-hydroxycoumarin
3-(alpha-Phenyl-beta-acetylaethyl)-4-hydroxycumarin
3-(alpha-Phenyl-beta-acetylethyl)-4-hydroxycoumarin
4-Hydroxy-3- (3-oxo-1-fenyl-butyl) cumarine
4-Hydroxy-3- (3-oxo-1-phenyl-butyl)-cumarin
4-Hydroxy-3-(3-oxo-1-fenyl-butyl) cumarine
4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2H-1-benzopyran-2-one
4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one
4-Hydroxy-3-(3-oxo-1-phenylbutyl)coumarin
4-Hydroxy-3-(3-oxo-1-phenyl-butyl)-cumarin
4-Idrossi-3- (3-oxo-)-fenil-butil)-cumarine
4-Idrossi-3-(3-oxo-)-fenil-butil)-cumarine
4-Idrossi-3-(3-oxo-1-fenil-butil)-cumarine
4oh-Coumarin deriv.
aldo Brand OF warfarin sodium
Aldocumar
Antigen brand OF warfarin sodium
Apotex brand OF warfarin sodium
apo-Warfarin
Arab rat death
Arab rat deth
Athrombin
Athrombine-K
Athrombin-K
Bailly brand OF warfarin sodium
Boots brand OF warfarin sodium
Bristol-myers squibb brand OF warfarin sodium
Brumolin
Choice
Compound 42
CO-Rax
Coumadin
Coumadin Tabs
Coumadin®|Marevan®|panwarfin
Coumadine
Coumafen
Coumafene
Coumaphen
Coumaphene
Coumarins
Coumefene
Cov-R-tox
D-CON
delta-CON
Dethmor
Dethnel
Dicusat e
DL-3-(alpha-Acetonylbenzyl)-4-hydroxycoumarin
Eastern states duocide
Estedi brand OF warfarin sodium
fasco Fascrat powder
Frass-ratron
Genpharm brand OF warfarin sodium
Gen-warfarin
Goldshield brand OF warfarin sodium
Jantoven
Killgerm sewarin P
Kumader
Kumadu
Kumatox
Kypfarin
Latka 42
Liqua-tox
Maag rattentod cum
Marevan
|
Mar-frin
Martin'S mar-frin
Maveran
Mouse pak
NSC-59813
PANWARFIN
Place-pax
Potassium, warfarin
Prothromadin
Rat & mice bait
Rat and mice bait
Rat-alpha-way
Rat-a-way
Rat-beta-gon
Rat-b-gon
Rat-gard
Rat-kill
Rat-mix
Rat-O-cide #2
Rat-O-cide no. 2
Rat-ola
Ratorex
Ratox
Ratoxin
Ratron
Ratron g
Rats-NO-more
Ratten-koederrohr
Rattenstreupulver neu schacht
Rattenstreupulver new schacht
Rattentraenke
Rat-trol
Rattunal
RAX
RCR Grey squirrel killer concentrate
Rodafarin
Rodafarin c
ro-Deth
Rodex
Rodex blox
Rosex
Rough & ready mouse mix
Rough and ready mouse mix
Sakarat
Sewarin
Sodium, warfarin
Sofarin
Solfarin
Sorexa plus
Spray-trol brand roden-trol
Tedicumar
Temus W
Tintorane
Tox-hid
Twin light rat away
Vampirinip II
Vampirinip III
Waran
Warf 42
Warfant
Warfarat
WARFARIN
Warfarin Plus
Warfarin potassium
Warfarin Q
Warfarin sodium
Warfarina
Warfarine
Warficide
Warfilone
Zoocoumarin
|
|
Interventional clinical trials:
(show all 16)
# |
Name |
Status |
NCT ID |
Phase |
Drugs |
1 |
Better Evidence and Translation for Calciphylaxis |
Recruiting |
NCT05018221 |
Phase 3 |
Vitamin K1;Magnesium citrate;Sodium Thiosulfate;Placebo injection (normal saline);Placebo capsule (Vitamin K1);Placebo tablet (Magnesium citrate) |
2 |
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of SNF472 When Added to Background Care for the Treatment of Calciphylaxis |
Active, not recruiting |
NCT04195906 |
Phase 3 |
Experimental: SNF472;Placebo Comparator: Placebo;Experimatenl SNF472 (Open-label) |
3 |
A Phase 3, Intravenous Sodium Thiosulfate for Acute Calciphylaxis Treatment: A Multicenter, Randomized, Double-blind, Placebo-controlled, Clinical Trial |
Terminated |
NCT03150420 |
Phase 3 |
Sodium Thiosulfate;Placebo-Normal Saline |
4 |
Randomized Double Blind Placebo Controlled Trial of Sodium Thiosulfate for the Treatment of Pain Associated With Calcific Uremic Arteriolopathy Followed by a Single Armed Extension Phase to Prospectively Observe Lesion Progression in the Presence of Sodium Thiosulfate Treatment |
Terminated |
NCT02527213 |
Phase 3 |
Sodium thiosulfate;Placebo |
5 |
Phase 2 Open Label Single Arm Repeat Dose Study to Assess the Effect of SNF472 on Wound Healing in Uraemic Calciphylaxis Patients |
Completed |
NCT02790073 |
Phase 2 |
SNF472 |
6 |
Evaluation of Efficacy of Lanthanum Carbonate (Fosrenol) in Patients With Calciphylaxis |
Completed |
NCT01289626 |
Phase 1 |
lanthanum carbonate;Lanthanum for calciphylaxis |
7 |
European Calciphylaxis Registry Network |
Unknown status |
NCT02635373 |
|
|
8 |
National Follow-up of Dialysis Patients With Sodium Thiosufate-treated Calciphylaxis Under Temporary Use Authorization |
Unknown status |
NCT03146793 |
|
Sodium Thiosulfate |
9 |
Pathophysiology of Martorell Hypertensive Ischemic Leg Ulcer (HYTILU): A Comparison of Martorell HYTILU, Calciphylaxis and Venous Ulcer (Control) |
Completed |
NCT01578382 |
|
|
10 |
Calciphylaxis : Population, Risk Factors, Diagnostic Practice, Therapeutic and Outcome : a Multicentric, Retrospective Cohort |
Completed |
NCT02854046 |
|
|
11 |
Evaluation of Vitamin K Supplementation for Calcific Uremic Arteriolopathy |
Completed |
NCT02278692 |
|
|
12 |
Partners Calciphylaxis Biobank and Patient Registry |
Recruiting |
NCT03032835 |
|
|
13 |
Effects of Human Amniotic Mesenchymal Stem Cells (hAMSCs) on Wound Healing in Uremic Calciphylaxis Patients: an Open Label Single Arm Study |
Active, not recruiting |
NCT04592640 |
|
|
14 |
Efficacy of Rheopheresis as Adjuvant Treatment of Calciphylaxis in Hemodialysis Patients : a Prospective Randomized Controled Single-blind Trial |
Not yet recruiting |
NCT04654000 |
|
|
15 |
Retrospective Study Evaluating the Contribution of Rheopheresis in the Treatment of Uremic Calciphylaxis |
Not yet recruiting |
NCT05633121 |
|
|
16 |
Observational Follow-up to ST-001 Calciphylaxis Pain Treatment With Intravenous Sodium Thiosulfate |
Terminated |
NCT03319914 |
|
|
Cochrane evidence based reviews: calciphylaxis
|