MCID: CNC001
MIFTS: 30

Cancerophobia

Categories: Cancer diseases, Mental diseases

Aliases & Classifications for Cancerophobia

MalaCards integrated aliases for Cancerophobia:

Name: Cancerophobia 12 15 73
Fear of Getting Cancer 12
Cancer Phobia 12

Classifications:



External Ids:

Disease Ontology 12 DOID:602
NCIt 50 C35492
SNOMED-CT 68 34563004
UMLS 73 C0233705

Summaries for Cancerophobia

MalaCards based summary : Cancerophobia, also known as fear of getting cancer, is related to breast medullary carcinoma and papillary serous adenocarcinoma. An important gene associated with Cancerophobia is MCIDAS (Multiciliate Differentiation And DNA Synthesis Associated Cell Cycle Protein), and among its related pathways/superpathways are Homologous DNA Pairing and Strand Exchange and Cell cycle Role of SCF complex in cell cycle regulation. The drugs Dopamine and Norepinephrine have been mentioned in the context of this disorder. Affiliated tissues include breast, bone and ovary, and related phenotypes are Decreased homologous recombination repair frequency and Decreased homologous recombination repair frequency

Wikipedia : 76 Cancer phobia, also known as carcinophobia, is an anxiety disorder characterized by the chronic fear of... more...

Related Diseases for Cancerophobia

Diseases related to Cancerophobia via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 47)
# Related Disease Score Top Affiliating Genes
1 breast medullary carcinoma 10.0 BRCA1 PGR
2 papillary serous adenocarcinoma 10.0 BRCA1 PGR
3 uterine corpus cancer 10.0 BRCA1 PGR
4 in situ carcinoma 10.0 BRCA1 PGR
5 estrogen-receptor negative breast cancer 10.0 BRCA1 PGR
6 hereditary site-specific ovarian cancer syndrome 9.9 BRCA1 BRCA2
7 breast reconstruction 9.9 BRCA1 BRCA2
8 tuberculous salpingitis 9.9 BRCA1 BRCA2
9 breast ductal carcinoma 9.9 BRCA1 PGR
10 breast-ovarian cancer, familial 1 9.9 BRCA1 BRCA2
11 fallopian tube adenocarcinoma 9.9 BRCA1 BRCA2
12 premature menopause 9.9 BRCA1 BRCA2
13 peritoneum cancer 9.9 BRCA1 BRCA2
14 fallopian tube disease 9.9 BRCA1 BRCA2
15 lynch syndrome 9.9 BRCA1 BRCA2
16 lynch syndrome i 9.9 BRCA1 BRCA2
17 mutagen sensitivity 9.9 BRCA1 BRCA2
18 fanconi anemia, complementation group q 9.9 BRCA1 BRCA2
19 ovarian cancer 1 9.8 BRCA1 BRCA2
20 hereditary breast ovarian cancer syndrome 9.8 BRCA1 BRCA2
21 gonadal disease 9.8 BRCA1 BRCA2
22 cowden disease 9.8 BRCA1 BRCA2
23 li-fraumeni syndrome 9.8 BRCA1 BRCA2
24 endocrine gland cancer 9.8 BRCA1 BRCA2
25 synchronous bilateral breast carcinoma 9.7 BRCA1 BRCA2 PGR
26 glycogen-rich clear cell breast carcinoma 9.7 BRCA1 BRCA2 PGR
27 bilateral breast cancer 9.7 BRCA1 BRCA2 PGR
28 primary peritoneal carcinoma 9.7 BRCA1 BRCA2 PGR
29 pre-malignant neoplasm 9.7 BRCA1 BRCA2 PGR
30 fallopian tube carcinoma 9.7 BRCA1 BRCA2 PGR
31 dysgerminoma of ovary 9.7 BRCA1 BRCA2 PGR
32 breast carcinoma in situ 9.7 BRCA1 BRCA2 PGR
33 malignant ovarian surface epithelial-stromal neoplasm 9.7 BRCA1 BRCA2 PGR
34 pancreas adenocarcinoma 9.7 BRCA1 BRCA2
35 ovary epithelial cancer 9.7 BRCA1 BRCA2 PGR
36 female breast cancer 9.7 BRCA1 BRCA2 PGR
37 ovarian cancer 9.7 BRCA1 BRCA2 PGR
38 sporadic breast cancer 9.7 BRCA1 BRCA2 PGR
39 ductal carcinoma in situ 9.7 BRCA1 BRCA2 PGR
40 female reproductive system disease 9.7 BRCA1 BRCA2 PGR
41 reproductive system disease 9.7 BRCA1 BRCA2 PGR
42 ovarian disease 9.7 BRCA1 BRCA2 PGR
43 breast disease 9.7 BRCA1 BRCA2 PGR
44 adamantinoma of long bones 9.7 BRCA1 BRCA2 PGR
45 fanconi anemia, complementation group a 9.6 BRCA1 BRCA2
46 endometrial cancer 9.6 BRCA1 BRCA2 PGR
47 nosophobia 9.5 BRCA1 BRCA2 MCIDAS PGR

Graphical network of the top 20 diseases related to Cancerophobia:



Diseases related to Cancerophobia

Symptoms & Phenotypes for Cancerophobia

GenomeRNAi Phenotypes related to Cancerophobia according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased homologous recombination repair frequency GR00151-A-1 10.4 BRCA1
2 Decreased homologous recombination repair frequency GR00151-A-2 10.4 BRCA1
3 Decreased homologous recombination repair frequency GR00236-A-1 10.4 BRCA1 BRCA2 PGR
4 Decreased homologous recombination repair frequency GR00236-A-2 10.4 BRCA1 BRCA2 PGR
5 Decreased homologous recombination repair frequency GR00236-A-3 10.4 BRCA1 BRCA2
6 Decreased viability after ionizing radiation GR00232-A-2 9.16 BRCA1 BRCA2
7 Decreased viability with cisplatin GR00101-A-4 8.96 BRCA1 BRCA2
8 Synthetic lethal with cisplatin GR00101-A-1 8.62 BRCA1 BRCA2

MGI Mouse Phenotypes related to Cancerophobia:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 limbs/digits/tail MP:0005371 9.13 BRCA1 BRCA2 PGR
2 neoplasm MP:0002006 8.8 BRCA1 BRCA2 PGR

Drugs & Therapeutics for Cancerophobia

Drugs for Cancerophobia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 55)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dopamine Approved Phase 3 51-61-6, 62-31-7 681
2
Norepinephrine Approved Phase 3 51-41-2 439260
3
Progesterone Approved, Vet_approved Phase 3 57-83-0 5994
4
Exemestane Approved, Investigational Phase 3 107868-30-4 60198
5
Letrozole Approved, Investigational Phase 3 112809-51-5 3902
6
Tamoxifen Approved Phase 3 10540-29-1 2733526
7
Anastrozole Approved, Investigational Phase 3 120511-73-1 2187
8
Citric Acid Approved, Nutraceutical, Vet_approved Phase 3 77-92-9 311
9 Analgesics Phase 3
10 Neurotransmitter Agents Phase 3
11 Hormones Phase 3
12 Serotonin and Noradrenaline Reuptake Inhibitors Phase 3
13 Duloxetine Hydrochloride Phase 3
14 Peripheral Nervous System Agents Phase 3
15 Antidepressive Agents Phase 3
16 Estrogens Phase 3
17 Dopamine Agents Phase 3
18 Aromatase Inhibitors Phase 3
19 Neurotransmitter Uptake Inhibitors Phase 3
20 Psychotropic Drugs Phase 3
21 Bone Density Conservation Agents Phase 3
22 Estrogen Antagonists Phase 3
23 Antineoplastic Agents, Hormonal Phase 3
24 Citrate Phase 3
25 Calcium, Dietary Phase 3
26 Estrogen Receptor Modulators Phase 3
27 Selective Estrogen Receptor Modulators Phase 3
28 Steroid Synthesis Inhibitors Phase 3
29 Estrogen Receptor Antagonists Phase 3
30 Anticoagulants Phase 3
31 Hormone Antagonists Phase 3
32 Chelating Agents Phase 3
33 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3
34
Serotonin Investigational, Nutraceutical Phase 3 50-67-9 5202
35
Fluorouracil Approved Phase 2 51-21-8 3385
36
Paclitaxel Approved, Vet_approved Phase 2 33069-62-4 36314
37
Pancrelipase Approved, Investigational Phase 2 53608-75-6
38
Irinotecan Approved, Investigational Phase 2 100286-90-6, 97682-44-5 60838
39
Oxaliplatin Approved, Investigational Phase 2 61825-94-3 43805 6857599 5310940 9887054
40
Gemcitabine Approved Phase 2 95058-81-4 60750
41
Camptothecin Experimental Phase 2 7689-03-4
42 Antiviral Agents Phase 2
43 Immunosuppressive Agents Phase 2
44 Immunologic Factors Phase 2
45 Antineoplastic Agents, Phytogenic Phase 2
46 Antimetabolites, Antineoplastic Phase 2
47 Antimitotic Agents Phase 2
48 Anti-Infective Agents Phase 2
49 Antimetabolites Phase 2
50 pancreatin Phase 2

Interventional clinical trials:

(show all 45)
# Name Status NCT ID Phase Drugs
1 S1202: Duloxetine Hydrochloride for Muscle/Joint Pain in Early-Stage Breast Cancer Receiving Hormone Therapy Active, not recruiting NCT01598298 Phase 3 duloxetine hydrochloride
2 Tamoxifen Citrate, Letrozole, Anastrozole, or Exemestane With or Without Chemotherapy in Treating Patients With Invasive RxPONDER Breast Cancer Active, not recruiting NCT01272037 Phase 3 Anastrozole;Exemestane;Letrozole;Systemic Chemotherapy;Tamoxifen Citrate
3 Brief CBT for Anxiety and Advanced Cancer Completed NCT00706290 Phase 2
4 Impact of a Group Intervention on Breast Cancer Patient's Adjustment and Emotion Regulation at the End of Treatment Completed NCT01797354 Phase 2
5 S1505: Combination Chemotherapy or Gemcitabine Hydrochloride and Paclitaxel Albumin-Stabilized Nanoparticle Formulation Before Surgery in Treating Patients With Pancreatic Cancer That Can Be Removed by Surgery Recruiting NCT02562716 Phase 2 Fluorouracil;Gemcitabine Hydrochloride;Irinotecan Hydrochloride;Oxaliplatin;Paclitaxel Albumin-Stabilized Nanoparticle Formulation
6 Fear of Recurrence Pilot Intervention for Women With Breast Cancer Completed NCT01354041 Phase 1
7 Feasibility and Efficacy of Internet-delivered CBT for Insomnia in a National Cohort of Danish Breast Cancer Survivors Unknown status NCT02444026 Not Applicable
8 Smart-phone Health Coaching Intervention to Promote Maintenance of Exercise in Breast Cancer Survivors:Protocol Unknown status NCT02620735 Not Applicable
9 A Therapy Intervention to Address Fear of Recurrence in Men and Women With Cancer Completed NCT02382315 Not Applicable
10 Targeted eHealth Intervention to Reduce Fear of Recurrence Among Breast Cancer Survivors Completed NCT03384992 Not Applicable
11 Fear of Cancer Recurrence (FoR) Trajectory During Radiation Treatment Completed NCT02599506
12 Investigation of Three Approaches to Address Fear of Recurrence Among Breast Cancer Survivors Completed NCT02611544 Not Applicable
13 Evidence-informed Choice for Women Participating in Mammography Screening Completed NCT01335906 Not Applicable
14 (Cost-)Effectiveness of Mindfulness-Based Cognitive Therapy (MBCT) in Cancer Patients Completed NCT02138513 Not Applicable
15 Stress Management for Cancer Survivors Completed NCT01888523 Not Applicable
16 Health Benefits of Expressive Writing: Study One Completed NCT03546673 Not Applicable
17 Evaluation Study of Fear of Cancer Recurrence: Detection, Measure and Risk Factors in Lymphoma Survivorship Recruiting NCT03260855 Not Applicable
18 Cognitive-Existential Group Therapy to Reduce Fear of Cancer Recurrence: A RCT Study Recruiting NCT03270995 Not Applicable
19 A Communication Skills Package to Prevent Fear of Cancer Recurrence Recruiting NCT03468881
20 Mind Body Program for Fear of Recurrence Recruiting NCT03695406 Not Applicable
21 Attention and Interpretation Modification (AIM) for Fear of Breast Cancer Recurrence: An Intervention Development Study Recruiting NCT01517945
22 Improving Emotion Regulation at the End of Breast Cancer Treatment Recruiting NCT03336827 Not Applicable
23 Yoga for Psychological Distress in Gynecologic, Gastrointestinal, or Thoracic Cancer Recruiting NCT03385577 Not Applicable
24 Conquer Fear SUPPORT Intervention in Supporting Patients With Stage III-IV Lung or Gynecologic Cancer Recruiting NCT03776253 Not Applicable
25 Cancer Related Cognitive Impairment After Chemotherapy: Evaluation of Potential Therapeutic Interventions Recruiting NCT03736460 Not Applicable
26 MBCT for Cancer Patients in Follow-Up Recruiting NCT03591237 Not Applicable
27 Individual Follow-up After Rectal Cancer - Focus on the Needs of the Patient Recruiting NCT03622437 Not Applicable
28 Online MBSR Program for Cancer Survivors With Chronic Neuropathic Pain Recruiting NCT02758197 Not Applicable
29 Cognitively-Based Compassion Training for Breast Cancer Survivors Recruiting NCT03305952 Not Applicable
30 Acceptance and Commitment Therapy (ACT) for Anxious Cancer Survivors Recruiting NCT02550925 Not Applicable
31 Impact of an Intervention Combining Self-care and Hypnosis on the Well-being of Cancer Patients and Their Partners Recruiting NCT03144154 Not Applicable
32 Cognition in Allogeneic Stem Cell Transplanted Patients and Sports Recruiting NCT02533947 Not Applicable
33 EXamining PErsonalised Radiation Therapy for Low-risk Early Breast Cancer Recruiting NCT02889874 Not Applicable
34 Stepped-Care Telehealth for Distress in Rural Cancer Survivors Recruiting NCT03060096 Not Applicable
35 Follow-up of Endometrial Cancer Patients Active, not recruiting NCT01853865 Not Applicable
36 Survivorship in Lynch Syndrome Families Active, not recruiting NCT01126840
37 Exercise During Active Surveillance for Prostate Cancer Active, not recruiting NCT03203460 Not Applicable
38 A Research Study of Patient-led Surveillance Compared to Clinician-led Surveillance in People Treated for Localised Melanoma. Enrolling by invitation NCT03581188 Not Applicable
39 Mini-AFTERc Intervention for Fear of Cancer Recurrence Not yet recruiting NCT03763825 Not Applicable
40 Compare the Effects of NLSCP and Interactive ICT Supported HAP on Differentiate Diagnosed Thyroid Cancer Patients Not yet recruiting NCT03757637 Not Applicable
41 Effect of a Resilience Model-Based Care Plan in Newly Diagnosed Colorectal Cancer Patients Not yet recruiting NCT03277235 Not Applicable
42 Group Metacognitive Therapy for Anxiety and Depression in Cancer Survivors Not yet recruiting NCT03424512 Not Applicable
43 The SEAMLESS Study: Smartphone App-based Mindfulness for Cancer Survivors Not yet recruiting NCT03557762 Not Applicable
44 Delayed-immediate Versus Delayed Breast Reconstruction in Breast Cancer Patients With Mastectomy and Radiation Therapy Not yet recruiting NCT03730922 Not Applicable
45 Prospective Study Evaluating the Use of PROSPECT to Reduce Insomnia in Patients With Early Stage Breast Cancer Terminated NCT02712437 Not Applicable

Search NIH Clinical Center for Cancerophobia

Genetic Tests for Cancerophobia

Anatomical Context for Cancerophobia

MalaCards organs/tissues related to Cancerophobia:

41
Breast, Bone, Ovary, Pancreas

Publications for Cancerophobia

Articles related to Cancerophobia:

# Title Authors Year
1
When cancerophobia and denial lead to death. ( 19538809 )
2009
2
Cancerophobia and breast fixation. ( 204570 )
1978
3
MANAGEMENT OF THE PATIENT WITH CANCEROPHOBIA AND CANCER. ( 14149368 )
1964
4
Cancerophobia and delusion. ( 13672768 )
1959

Variations for Cancerophobia

Expression for Cancerophobia

Search GEO for disease gene expression data for Cancerophobia.

Pathways for Cancerophobia

GO Terms for Cancerophobia

Cellular components related to Cancerophobia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 lateral element GO:0000800 8.62 BRCA1 BRCA2

Biological processes related to Cancerophobia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of transcription by RNA polymerase II GO:0045944 9.63 BRCA1 MCIDAS PGR
2 cell cycle GO:0007049 9.54 BRCA1 BRCA2 MCIDAS
3 DNA recombination GO:0006310 9.43 BRCA1 BRCA2
4 double-strand break repair via homologous recombination GO:0000724 9.4 BRCA1 BRCA2
5 double-strand break repair GO:0006302 9.32 BRCA1 BRCA2
6 intrinsic apoptotic signaling pathway in response to DNA damage GO:0008630 9.26 BRCA1 BRCA2
7 mammary gland development GO:0030879 9.16 BRCA2 PGR
8 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator GO:0006978 8.96 BRCA1 BRCA2
9 chordate embryonic development GO:0043009 8.62 BRCA1 BRCA2

Molecular functions related to Cancerophobia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 8.92 BRCA1 BRCA2 MCIDAS PGR

Sources for Cancerophobia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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