MCID: CNM001
MIFTS: 14

Canomad Syndrome

Categories: Immune diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Canomad Syndrome

MalaCards integrated aliases for Canomad Syndrome:

Name: Canomad Syndrome 53 59 73
Chronic Ataxic Neuropathy-Ophthalmoplegia-Igm Paraprotein-Cold Agglutinins-Disialosyl Antibodies Syndrome 59
Chronic Ataxic Neuropathy Ophthalmoplegia M-Protein Agglutination Disialosyl Antibodies Syndrome 53
Chronic Sensory Ataxic Neuropathy with Anti-Dyalosyl Igm Antibodies 59
Chronic Sensory Ataxic Neuropathy with Anti-Disialosyl Antibodies 53

Characteristics:

Orphanet epidemiological data:

59
canomad syndrome
Age of onset: Adult;

Classifications:

Orphanet: 59  
Rare neurological diseases


External Ids:

Orphanet 59 ORPHA71279
MESH via Orphanet 45 C537980
UMLS via Orphanet 74 C2931684
ICD10 via Orphanet 34 G61.8
UMLS 73 C2931684

Summaries for Canomad Syndrome

NIH Rare Diseases : 53 CANOMAD syndrome is a rare chronic immune-mediated demyelinating polyneuropathy. CANOMAD stands for Chronic Ataxic Neuropathy Ophthalmoplegia IgM paraprotein Cold Agglutinins Disialosyl antibodies. Signs and symptoms of CANOMAD may include loss of muscle, tendon, and joint sensation, abnormal gait (walk), ataxia, tingling sensation on the skin around the mouth or extremities, paralysis of eye muscles, difficulty swallowing and speaking, and rarely respiratory muscle weakness. This condition is caused by the presence of anti-diasialosyl antibodies in the body.  Oral or intravenous corticosteroids, �?-interferons, plasma exchange, intravenous immunoglobulin (IVIG), and cytotoxic drugs have all been used in treating CANOMAD with varying success.

MalaCards based summary : Canomad Syndrome, is also known as chronic ataxic neuropathy-ophthalmoplegia-igm paraprotein-cold agglutinins-disialosyl antibodies syndrome, and has symptoms including ataxia and ophthalmoplegia. Affiliated tissues include skin and eye.

Related Diseases for Canomad Syndrome

Symptoms & Phenotypes for Canomad Syndrome

UMLS symptoms related to Canomad Syndrome:


ataxia, ophthalmoplegia

Drugs & Therapeutics for Canomad Syndrome

Search Clinical Trials , NIH Clinical Center for Canomad Syndrome

Genetic Tests for Canomad Syndrome

Anatomical Context for Canomad Syndrome

MalaCards organs/tissues related to Canomad Syndrome:

41
Skin, Eye

Publications for Canomad Syndrome

Articles related to Canomad Syndrome:

# Title Authors Year
1
Corrigendum to "A case of false positive cardiac troponin I in CANOMAD syndrome" [Int. J. Cardiol. 222 (2016) 359-360]. ( 29499853 )
2018
2
A case of false positive cardiac troponin I in CANOMAD syndrome. ( 27500764 )
2016

Variations for Canomad Syndrome

Expression for Canomad Syndrome

Search GEO for disease gene expression data for Canomad Syndrome.

Pathways for Canomad Syndrome

GO Terms for Canomad Syndrome

Sources for Canomad Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....