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MCID: CNM001
MIFTS: 17
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Canomad Syndrome
Categories:
Immune diseases, Neuronal diseases, Rare diseases
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MalaCards integrated aliases for Canomad Syndrome:
Characteristics:Orphanet epidemiological data:58
canomad syndrome
Age of onset: Adult; Classifications:
ICD10:
33
Orphanet: 58
Rare neurological diseases External Ids:
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NIH Rare Diseases :
52
CANOMAD syndrome is a rare chronic immune-mediated demyelinating polyneuropathy. CANOMAD stands for Chronic Ataxic Neuropathy Ophthalmoplegia IgM paraprotein Cold Agglutinins Disialosyl antibodies . Signs and symptoms of CANOMAD may include loss of muscle, tendon, and joint sensation, abnormal gait (walk), ataxia , tingling sensation on the skin around the mouth or extremities, paralysis of eye muscles, difficulty swallowing and speaking, and rarely respiratory muscle weakness. This condition is caused by the presence of anti-diasialosyl antibodies in the body. Oral or intravenous corticosteroids , ?-interferons, plasma exchange, intravenous immunoglobulin (IVIG), and cytotoxic drugs have all been used in treating CANOMAD with varying success.
MalaCards based summary : Canomad Syndrome, also known as chronic ataxic neuropathy-ophthalmoplegia-igm paraprotein-cold agglutinins-disialosyl antibodies syndrome, is related to ataxia and polyneuropathy, adult-onset and miller fisher syndrome, and has symptoms including ataxia and ophthalmoplegia. Affiliated tissues include eye, skin and testes. |
Diseases related to Canomad Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:
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UMLS symptoms related to Canomad Syndrome:ataxia, ophthalmoplegia |
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MalaCards organs/tissues related to Canomad Syndrome:40
Eye,
Skin,
Testes
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Articles related to Canomad Syndrome:
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Search
GEO
for disease gene expression data for Canomad Syndrome.
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