MCID: CPP003
MIFTS: 31

Cap Polyposis

Categories: Gastrointestinal diseases, Rare diseases

Aliases & Classifications for Cap Polyposis

MalaCards integrated aliases for Cap Polyposis:

Name: Cap Polyposis 58
Inflammatory Myoglandular Polyps 58
Eroded Polypoid Hyperplasia 58
Cap Inflammatory Polyposis 58
Polypoid Prolapsing Folds 58

Characteristics:

Orphanet epidemiological data:

58
cap polyposis
Inheritance: Not applicable; Prevalence: <1/1000000 (Worldwide); Age of onset: Adolescent,Adult,Childhood,Elderly;

Classifications:

Orphanet: 58  
Rare gastroenterological diseases


Summaries for Cap Polyposis

MalaCards based summary : Cap Polyposis, also known as inflammatory myoglandular polyps, is related to inflammatory bowel disease and solitary rectal ulcer syndrome. An important gene associated with Cap Polyposis is ALB (Albumin), and among its related pathways/superpathways are Metabolism of proteins and HIV Life Cycle. Affiliated tissues include colon, lung and eye, and related phenotypes are colorectal polyposis and constipation

Related Diseases for Cap Polyposis

Diseases related to Cap Polyposis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 73)
# Related Disease Score Top Affiliating Genes
1 inflammatory bowel disease 29.1 MUC5AC MUC3A ALB
2 solitary rectal ulcer syndrome 10.4
3 constipation 10.3
4 protein-losing enteropathy 10.3
5 gastrointestinal ulceration, recurrent, with dysfunctional platelets 10.3
6 colitis 10.2
7 inflammatory bowel disease 3 10.1
8 villous adenoma 10.1
9 proctitis 10.1
10 pelvic organ prolapse 10.1
11 clostridium difficile colitis 10.1
12 ulcerative colitis 10.1
13 polyposis, skin pigmentation, alopecia, and fingernail changes 10.1 MUC5AC ALB
14 acute cholangitis 10.0 MUC5AC ALB
15 helicobacter pylori infection 10.0
16 diarrhea 10.0
17 intestinal disease 10.0
18 bile reflux 10.0 MUC5AC ALB
19 keratoconjunctivitis sicca 10.0 MUC5AC ALB
20 keratoconjunctivitis 10.0 MUC5AC ALB
21 biliary papillomatosis 10.0 MUC5AC MUC2
22 pancreatic mucinous cystadenoma 10.0 MUC5AC MUC2
23 diverticulitis 10.0 MUC5AC ALB
24 ovarian mucinous adenocarcinoma 10.0 MUC5AC MUC2
25 middle ear disease 10.0 MUC5AC ALB
26 meconium ileus 10.0 MUC5AC MUC2
27 conjunctival disease 10.0 MUC5AC ALB
28 pseudomyxoma peritonei 10.0 MUC5AC MUC2
29 ampulla of vater adenocarcinoma 10.0 MUC5AC MUC2
30 common cold 10.0 MUC5AC ALB
31 nose disease 10.0 MUC5AC ALB
32 signet ring cell adenocarcinoma 10.0 MUC5AC MUC2
33 tubular adenocarcinoma 10.0 MUC5AC MUC2
34 lung mucoepidermoid carcinoma 10.0 MUC5AC MUC3A
35 bronchial disease 9.9 MUC5AC ALB
36 pancreatic ductal carcinoma 9.9 MUC5AC MUC2
37 otitis media 9.9 MUC5AC ALB
38 cystadenocarcinoma 9.9 MUC5AC MUC2
39 nevus, epidermal 9.9
40 fibrosclerosis, multifocal 9.9
41 deficiency anemia 9.9
42 crohn's colitis 9.9
43 hemopericardium 9.9
44 pericardial effusion 9.9
45 gastritis 9.9
46 gastrointestinal system disease 9.9
47 crohn's disease 9.9
48 irritable bowel syndrome 9.9
49 hypoglycemia 9.9
50 chronic erosive gastritis 9.9

Graphical network of the top 20 diseases related to Cap Polyposis:



Diseases related to Cap Polyposis

Symptoms & Phenotypes for Cap Polyposis

Human phenotypes related to Cap Polyposis:

58 31 (show all 8)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 colorectal polyposis 58 31 obligate (100%) Obligate (100%) HP:0200063
2 constipation 58 31 hallmark (90%) Very frequent (99-80%) HP:0002019
3 abdominal pain 58 31 hallmark (90%) Very frequent (99-80%) HP:0002027
4 hematochezia 58 31 hallmark (90%) Very frequent (99-80%) HP:0002573
5 chronic atrophic gastritis 58 31 hallmark (90%) Very frequent (99-80%) HP:0002582
6 weight loss 58 31 frequent (33%) Frequent (79-30%) HP:0001824
7 abdominal distention 58 31 frequent (33%) Frequent (79-30%) HP:0003270
8 diarrhea 58 Frequent (79-30%)

Drugs & Therapeutics for Cap Polyposis

Search Clinical Trials , NIH Clinical Center for Cap Polyposis

Genetic Tests for Cap Polyposis

Anatomical Context for Cap Polyposis

MalaCards organs/tissues related to Cap Polyposis:

40
Colon, Lung, Eye, Skin

Publications for Cap Polyposis

Articles related to Cap Polyposis:

(show top 50) (show all 58)
# Title Authors PMID Year
1
[A case of cap polyposis achieving complete remission by Helicobacter pylori eradication therapy]. 61
33563859 2021
2
Endoscopic mucosal resection for cap poliposis treatment. 61
31960689 2020
3
Cap polyposis in children: case report and literature review. 61
30426196 2019
4
Cap Polyposis Masquerading as Inflammatory Bowel Disease in a Child. 61
27437929 2018
5
Successful laparoscopic resection for cap polyposis: case report, literature review. 61
29971597 2018
6
Polypectomy for Recurrent Inflammatory Cap Polyposis Combined with Argon Plasma Coagulation. 61
29774225 2018
7
Dysbiosis-Associated Polyposis of the Colon-Cap Polyposis. 61
29867933 2018
8
Cap polyposis refractory to Helicobacter pylori eradication treated with endoscopic submucosal dissection. 61
29085564 2017
9
A Case of Cap Polyposis with Epidermal Nevus in an Infant. 61
28378565 2017
10
Protein-losing pseudomembranous colitis with cap polyposis-like features. 61
28522919 2017
11
[The first case of cap polyposis in Denmark]. 61
25497653 2014
12
Polypectomy to eradicate cap polyposis with protein-losing enteropathy. 61
25287098 2014
13
Inflammatory "Cap" Polyposis: A Case Report of a Rare Nonneoplastic Colonic Polyposis. 61
23994878 2014
14
A case of cap polyposis remission by betamethasone enema after antibiotics therapy including Helicobacter pylori eradication. 61
24949613 2014
15
Cap polyposis and colitis cystica profunda: a rare association. 61
24118052 2014
16
Rectal cap polyposis masquerading as ulcerative colitis with pseudopolyposis and presenting as chronic anemia: a case study with review of literature. 61
23828750 2013
17
Cap polyposis: a rare cause of rectal bleeding in children. 61
23864782 2013
18
Cap polyposis mistaken for Crohn's disease: case report and review of literature. 61
22766527 2013
19
Cap-polyposis-like gastropathy with hypoproteinemia treated with H. pylori eradication. 61
24088754 2013
20
Inflammatory cap polyposis in a 42-year-old male. 61
23416507 2013
21
Nine-year follow-up from onset to spontaneous complete remission of cap polyposis. 61
23370743 2013
22
Solitary rectal cap polyp: Case report and review of the literature. 61
22816031 2012
23
Long-term outcome of cap polyposis, with special reference to the effects of steroid therapy. 61
22078102 2012
24
Successful management of cap polyposis with eradication of Helicobacter pylori relapsing 15 years after remission on steroid therapy. 61
22333383 2012
25
[A case of cap polyposis complicated with idiopathic retroperitoneal fibrosis]. 61
22113045 2011
26
Unusual colon polyps. Diagnosis: Cap polyposis. 61
21878333 2011
27
Cap polyposis with protein-losing enteropathy. 61
21869875 2011
28
Can the stomach be a target of cap polyposis? 61
20405375 2010
29
Remission of cap polyposis maintained for more than three years after infliximab treatment. 61
20431770 2009
30
Cap polyposis (CP) which relapsed after remission by avoiding straining at defecation, and was cured by Helicobacter pylori eradication therapy. 61
19952483 2009
31
[Cap polyposis]. 61
18592452 2008
32
Hypoalbuminaemia and colonic polyps: a case of protein-losing enteropathy with cap polyposis? 61
17847696 2007
33
[Cap polyposis: an unrecognized condition]. 61
17092208 2006
34
[Cap polyposis and Helicobacter pylori]. 61
16363555 2005
35
Cap polyposis: an inflammatory disorder or a spectrum of mucosal prolapse syndrome? 61
16099801 2005
36
Confined progression of cap polyposis along the anastomotic line, implicating the role of inflammatory responses in the pathogenesis. 61
16111972 2005
37
Rectal prolapse and cap polyposis: the missing link. 61
15785885 2005
38
Infliximab failure in cap polyposis. 61
15647206 2005
39
Pedunculated cap polyps preceding the development of cap polyposis: case report. 61
15729261 2005
40
Possible relationship between Helicobacter pylori infection and cap polyposis of the colon. 61
15610079 2004
41
Cap polyposis: further experience and review. 61
15164251 2004
42
Successful treatment of cap polyposis with infliximab. 61
15188181 2004
43
Gastrointestinal: cap polyposis. 61
12753160 2003
44
Spontaneous resolution of cap polyposis: case report. 61
12665781 2003
45
Does metronidazole cure cap polyposis by its antiinflammatory actions instead of by its antibiotic action? A case study. 61
12141801 2002
46
Cap polyposis cured by Helicobacter pylori eradication therapy. 61
12108681 2002
47
Asymptomatic cap polyposis from the sigmoid colon to the cecum. 61
11677493 2001
48
Proximal extension of cap polyposis confirmed by colonoscopy. 61
11522989 2001
49
Cap polyposis of the colon and rectum: an analysis of endoscopic findings. 61
11293761 2001
50
Features of cap polyposis by magnifying colonoscopy. 61
11115917 2000

Variations for Cap Polyposis

Expression for Cap Polyposis

Search GEO for disease gene expression data for Cap Polyposis.

Pathways for Cap Polyposis

Pathways related to Cap Polyposis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.13 MUC5AC MUC4 MUC3A MUC2
2
Show member pathways
13.09 MUC5AC MUC4 MUC3A MUC2 ALB
3
Show member pathways
11.97 MUC5AC MUC4 MUC3A MUC2
4
Show member pathways
11.72 MUC5AC MUC4 MUC3A MUC2
5
Show member pathways
11.61 MUC5AC MUC2
6
Show member pathways
11.42 MUC5AC MUC4 MUC3A MUC2
7
Show member pathways
10.96 MUC5AC MUC4 MUC3A MUC2

GO Terms for Cap Polyposis

Cellular components related to Cap Polyposis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.62 MUC5AC MUC4 MUC3A ALB
2 extracellular space GO:0005615 9.56 MUC5AC MUC4 MUC2 ALB
3 extracellular matrix GO:0031012 9.33 MUC5AC MUC4 MUC2
4 mucus layer GO:0070701 8.96 MUC5AC MUC2
5 Golgi lumen GO:0005796 8.92 MUC5AC MUC4 MUC3A MUC2

Biological processes related to Cap Polyposis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 stimulatory C-type lectin receptor signaling pathway GO:0002223 9.26 MUC5AC MUC4 MUC3A MUC2
2 maintenance of gastrointestinal epithelium GO:0030277 9.16 MUC4 MUC2
3 O-glycan processing GO:0016266 8.92 MUC5AC MUC4 MUC3A MUC2

Molecular functions related to Cap Polyposis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular matrix structural constituent GO:0005201 8.96 MUC5AC MUC3A
2 extracellular matrix constituent, lubricant activity GO:0030197 8.62 MUC4 MUC3A

Sources for Cap Polyposis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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