MCID: CPP003
MIFTS: 34

Cap Polyposis

Categories: Gastrointestinal diseases, Rare diseases

Aliases & Classifications for Cap Polyposis

MalaCards integrated aliases for Cap Polyposis:

Name: Cap Polyposis 59
Inflammatory Myoglandular Polyps 59
Eroded Polypoid Hyperplasia 59
Cap Inflammatory Polyposis 59
Polypoid Prolapsing Folds 59

Characteristics:

Orphanet epidemiological data:

59
cap polyposis
Inheritance: Not applicable; Prevalence: <1/1000000 (Worldwide); Age of onset: Adolescent,Adult,Childhood,Elderly;

Classifications:



Summaries for Cap Polyposis

MalaCards based summary : Cap Polyposis, also known as inflammatory myoglandular polyps, is related to inflammatory bowel disease and mucinous intrahepatic cholangiocarcinoma. An important gene associated with Cap Polyposis is ALB (Albumin), and among its related pathways/superpathways are Metabolism of proteins and HIV Life Cycle. Affiliated tissues include colon, and related phenotypes are colorectal polyposis and constipation

Related Diseases for Cap Polyposis

Diseases related to Cap Polyposis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 49)
# Related Disease Score Top Affiliating Genes
1 inflammatory bowel disease 28.2 ALB MUC2 MUC3A
2 mucinous intrahepatic cholangiocarcinoma 10.2 MUC2 MUC5AC
3 bile duct cystadenocarcinoma 10.2 MUC2 MUC5AC
4 clear cell adenoma 10.2 MUC2 MUC5AC
5 solitary rectal ulcer syndrome 10.1
6 biliary papillomatosis 10.1 MUC2 MUC5AC
7 colloid carcinoma of the pancreas 10.1 MUC2 MUC5AC
8 superior mesenteric artery syndrome 10.1 MUC2 MUC5AC
9 ovarian mucinous neoplasm 10.1 MUC2 MUC5AC
10 meconium ileus 10.1 MUC2 MUC5AC
11 pancreatic mucinous cystadenoma 10.1 MUC2 MUC5AC
12 colitis 10.1
13 protein-losing enteropathy 10.1
14 hidradenocarcinoma 10.1 MUC2 MUC5AC
15 pseudomyxoma peritonei 10.1 MUC2 MUC5AC
16 gastric tubular adenocarcinoma 10.1 MUC2 MUC5AC
17 cystitis cystica 10.0 MUC2 MUC5AC
18 bile duct adenocarcinoma 10.0 MUC2 MUC5AC
19 cholecystitis 10.0 ALB MUC2
20 small intestinal adenocarcinoma 10.0 MUC2 MUC5AC
21 epstein-barr virus-associated gastric carcinoma 10.0 MUC2 MUC5AC
22 ulcerative colitis 9.9
23 respiratory system disease 9.9 ALB MUC5AC
24 gastrointestinal system cancer 9.9 ALB MUC2
25 filamentary keratitis 9.8 MUC4 MUC5AC
26 mucinous tubular and spindle renal cell carcinoma 9.8 MUC2 MUC4
27 nevus, epidermal 9.8
28 pelvic organ prolapse 9.8
29 helicobacter pylori infection 9.8
30 crohn's disease 9.8
31 mucositis 9.8
32 limbal stem cell deficiency 9.8 MUC4 MUC5AC
33 biliary tract neoplasm 9.7 MUC2 MUC4
34 polyposis, skin pigmentation, alopecia, and fingernail changes 9.7 ALB MUC2 MUC5AC
35 otitis media 9.6 ALB MUC2 MUC5AC
36 cystadenoma 9.6 MUC2 MUC4
37 dry eye syndrome 9.6 MUC4 MUC5AC
38 bile duct carcinoma 9.5 MUC2 MUC4
39 barrett esophagus 9.3 MUC2 MUC5AC
40 cystic fibrosis 9.3 MUC2 MUC3A MUC5AC
41 bile duct mucoepidermoid carcinoma 9.2 MUC2 MUC4 MUC5AC
42 chronic ethmoiditis 9.2 MUC2 MUC4 MUC5AC
43 ethmoid sinusitis 9.2 MUC2 MUC4 MUC5AC
44 mucoepidermoid carcinoma 9.2 MUC2 MUC4 MUC5AC
45 intrahepatic cholangiocarcinoma 9.2 MUC2 MUC4 MUC5AC
46 pancreas adenocarcinoma 9.2 MUC2 MUC4 MUC5AC
47 cholangiocarcinoma 8.7 ALB MUC2 MUC4 MUC5AC
48 pancreatic cancer 8.6 MUC2 MUC4 MUC5AC
49 colorectal cancer 1 8.5 MUC2 MUC3A MUC4 MUC5AC

Graphical network of the top 20 diseases related to Cap Polyposis:



Diseases related to Cap Polyposis

Symptoms & Phenotypes for Cap Polyposis

Human phenotypes related to Cap Polyposis:

59 32 (show all 8)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 colorectal polyposis 59 32 obligate (100%) Obligate (100%) HP:0200063
2 constipation 59 32 hallmark (90%) Very frequent (99-80%) HP:0002019
3 abdominal pain 59 32 hallmark (90%) Very frequent (99-80%) HP:0002027
4 hematochezia 59 32 hallmark (90%) Very frequent (99-80%) HP:0002573
5 chronic atrophic gastritis 59 32 hallmark (90%) Very frequent (99-80%) HP:0002582
6 weight loss 59 32 frequent (33%) Frequent (79-30%) HP:0001824
7 abdominal distention 59 32 frequent (33%) Frequent (79-30%) HP:0003270
8 diarrhea 59 Frequent (79-30%)

Drugs & Therapeutics for Cap Polyposis

Search Clinical Trials , NIH Clinical Center for Cap Polyposis

Genetic Tests for Cap Polyposis

Anatomical Context for Cap Polyposis

MalaCards organs/tissues related to Cap Polyposis:

41
Colon

Publications for Cap Polyposis

Articles related to Cap Polyposis:

(show all 48)
# Title Authors Year
1
Successful laparoscopic resection for cap polyposis: case report, literature review. ( 29971597 )
2018
2
Polypectomy for Recurrent Inflammatory Cap Polyposis Combined with Argon Plasma Coagulation. ( 29774225 )
2018
3
Dysbiosis-Associated Polyposis of the Colon-Cap Polyposis. ( 29867933 )
2018
4
A Case of Cap Polyposis with Epidermal Nevus in an Infant. ( 28378565 )
2017
5
Cap polyposis refractory to<i>Helicobacter pylori</i>eradication treated with endoscopic submucosal dissection. ( 29085564 )
2017
6
Protein-losing pseudomembranous colitis with cap polyposis-like features. ( 28522919 )
2017
7
Cap Polyposis Masquerading as Inflammatory Bowel Disease in a Child. ( 27437929 )
2016
8
A case of cap polyposis remission by betamethasone enema after antibiotics therapy including Helicobacter pylori eradication. ( 24949613 )
2014
9
Polypectomy to eradicate cap polyposis with protein-losing enteropathy. ( 25287098 )
2014
10
Cap polyposis mistaken for Crohn's disease: case report and review of literature. ( 22766527 )
2013
11
Cap-polyposis-like gastropathy with hypoproteinemia treated with H. pylori eradication. ( 24088754 )
2013
12
Nine-year follow-up from onset to spontaneous complete remission of cap polyposis. ( 23370743 )
2013
13
Cap polyposis: a rare cause of rectal bleeding in children. ( 23864782 )
2013
14
Rectal cap polyposis masquerading as ulcerative colitis with pseudopolyposis and presenting as chronic anemia: a case study with review of literature. ( 23828750 )
2013
15
Cap polyposis and colitis cystica profunda: a rare association. ( 24118052 )
2013
16
Inflammatory cap polyposis in a 42-year-old male. ( 23416507 )
2013
17
Long-term outcome of cap polyposis, with special reference to the effects of steroid therapy. ( 22078102 )
2012
18
Successful management of cap polyposis with eradication of Helicobacter pylori relapsing 15 years after remission on steroid therapy. ( 22333383 )
2012
19
Unusual colon polyps. Diagnosis: Cap polyposis. ( 21878333 )
2011
20
Cap polyposis with protein-losing enteropathy. ( 21869875 )
2011
21
Can the stomach be a target of cap polyposis? ( 20405375 )
2010
22
Remission of cap polyposis maintained for more than three years after infliximab treatment. ( 20431770 )
2009
23
Cap polyposis (CP) which relapsed after remission by avoiding straining at defecation, and was cured by Helicobacter pylori eradication therapy. ( 19952483 )
2009
24
Hypoalbuminaemia and colonic polyps: a case of protein-losing enteropathy with cap polyposis? ( 17847696 )
2007
25
Pedunculated cap polyps preceding the development of cap polyposis: case report. ( 15729261 )
2005
26
Rectal prolapse and cap polyposis: the missing link. ( 15785885 )
2005
27
Cap polyposis: an inflammatory disorder or a spectrum of mucosal prolapse syndrome? ( 16099801 )
2005
28
Confined progression of cap polyposis along the anastomotic line, implicating the role of inflammatory responses in the pathogenesis. ( 16111972 )
2005
29
Successful treatment of cap polyposis with infliximab. ( 15188181 )
2004
30
Possible relationship between Helicobacter pylori infection and cap polyposis of the colon. ( 15610079 )
2004
31
Cap polyposis: further experience and review. ( 15164251 )
2004
32
Spontaneous resolution of cap polyposis: case report. ( 12665781 )
2003
33
Gastrointestinal: cap polyposis. ( 12753160 )
2003
34
Does metronidazole cure cap polyposis by its antiinflammatory actions instead of by its antibiotic action? A case study. ( 12141801 )
2002
35
Cap polyposis cured by Helicobacter pylori eradication therapy. ( 12108681 )
2002
36
Solitary rectal ulcer syndrome presenting with rectal prolapse, severe mucorrhea and eroded polypoid hyperplasia: case report and review of the literature. ( 11493953 )
2001
37
Proximal extension of cap polyposis confirmed by colonoscopy. ( 11522989 )
2001
38
Asymptomatic cap polyposis from the sigmoid colon to the cecum. ( 11677493 )
2001
39
Cap polyposis of the colon and rectum: an analysis of endoscopic findings. ( 11293761 )
2001
40
A case of &amp;quot;cap polyposis&amp;quot;-like lesion associated with ulcerative colitis: is this a case of cap polyposis? ( 11095366 )
2000
41
Features of cap polyposis by magnifying colonoscopy. ( 11115917 )
2000
42
Successful treatment of cap polyposis by avoidance of intraluminal trauma: clues to pathogenesis. ( 10950064 )
2000
43
A case of cap polyposis investigated by scintigraphy with human serum albumin labeled with Tc-99m DTPA. ( 9712385 )
1998
44
Abnormal mucus in cap polyposis. ( 9518233 )
1998
45
Protein-losing enteropathy from cap polyposis. ( 7491082 )
1995
46
Clinicopathologic comparison of eroded polypoid hyperplasia and solitary rectal ulcer syndrome. ( 7848580 )
1994
47
Cap polyposis occurring in the postoperative course of pelvic surgery. ( 7828996 )
1994
48
Cap polyposis--an unusual cause of diarrhoea. ( 8491408 )
1993

Variations for Cap Polyposis

Expression for Cap Polyposis

Search GEO for disease gene expression data for Cap Polyposis.

Pathways for Cap Polyposis

Pathways related to Cap Polyposis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.13 MUC2 MUC3A MUC4 MUC5AC
2
Show member pathways
13.09 ALB MUC2 MUC3A MUC4 MUC5AC
3
Show member pathways
11.97 MUC2 MUC3A MUC4 MUC5AC
4
Show member pathways
11.72 MUC2 MUC3A MUC4 MUC5AC
5
Show member pathways
11.61 MUC2 MUC5AC
6
Show member pathways
11.42 MUC2 MUC3A MUC4 MUC5AC
7
Show member pathways
10.96 MUC2 MUC3A MUC4 MUC5AC

GO Terms for Cap Polyposis

Cellular components related to Cap Polyposis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.26 ALB MUC3A MUC4 MUC5AC
2 Golgi lumen GO:0005796 8.92 MUC2 MUC3A MUC4 MUC5AC

Biological processes related to Cap Polyposis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 stimulatory C-type lectin receptor signaling pathway GO:0002223 9.26 MUC2 MUC3A MUC4 MUC5AC
2 maintenance of gastrointestinal epithelium GO:0030277 9.16 MUC2 MUC4
3 O-glycan processing GO:0016266 8.92 MUC2 MUC3A MUC4 MUC5AC

Molecular functions related to Cap Polyposis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular matrix structural constituent GO:0005201 8.96 MUC3A MUC5AC
2 extracellular matrix constituent, lubricant activity GO:0030197 8.62 MUC3A MUC4

Sources for Cap Polyposis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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