MCID: CPP003
MIFTS: 34

Cap Polyposis

Categories: Gastrointestinal diseases, Rare diseases

Aliases & Classifications for Cap Polyposis

MalaCards integrated aliases for Cap Polyposis:

Name: Cap Polyposis 60
Inflammatory Myoglandular Polyps 60
Eroded Polypoid Hyperplasia 60
Cap Inflammatory Polyposis 60
Polypoid Prolapsing Folds 60

Characteristics:

Orphanet epidemiological data:

60
cap polyposis
Inheritance: Not applicable; Prevalence: <1/1000000 (Worldwide); Age of onset: Adolescent,Adult,Childhood,Elderly;

Classifications:



Summaries for Cap Polyposis

MalaCards based summary : Cap Polyposis, also known as inflammatory myoglandular polyps, is related to solitary rectal ulcer syndrome and colitis. An important gene associated with Cap Polyposis is ALB (Albumin), and among its related pathways/superpathways are Metabolism of proteins and HIV Life Cycle. Affiliated tissues include colon, and related phenotypes are colorectal polyposis and constipation

Related Diseases for Cap Polyposis

Diseases related to Cap Polyposis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 48)
# Related Disease Score Top Affiliating Genes
1 solitary rectal ulcer syndrome 10.3
2 colitis 10.2
3 protein-losing enteropathy 10.2
4 mucinous intrahepatic cholangiocarcinoma 10.1 MUC2 MUC5AC
5 bile duct cystadenocarcinoma 10.1 MUC2 MUC5AC
6 clear cell adenoma 10.1 MUC2 MUC5AC
7 biliary papillomatosis 10.1 MUC2 MUC5AC
8 superior mesenteric artery syndrome 10.1 MUC2 MUC5AC
9 colloid carcinoma of the pancreas 10.1 MUC2 MUC5AC
10 ulcerative colitis 10.0
11 ovarian mucinous neoplasm 10.0 MUC2 MUC5AC
12 pancreatic mucinous cystadenoma 10.0 MUC2 MUC5AC
13 meconium ileus 10.0 MUC2 MUC5AC
14 hidradenocarcinoma 10.0 MUC2 MUC5AC
15 pseudomyxoma peritonei 10.0 MUC2 MUC5AC
16 gastric tubular adenocarcinoma 10.0 MUC2 MUC5AC
17 common cold 10.0 ALB MUC5AC
18 cystitis cystica 10.0 MUC2 MUC5AC
19 bile duct adenocarcinoma 10.0 MUC2 MUC5AC
20 cholecystitis 10.0 ALB MUC2
21 epstein-barr virus-associated gastric carcinoma 10.0 MUC2 MUC5AC
22 intestinal disease 10.0 ALB MUC2
23 gastrointestinal system cancer 9.9 ALB MUC2
24 stomach disease 9.9 MUC2 MUC5AC
25 respiratory system disease 9.9 ALB MUC5AC
26 nevus, epidermal 9.9
27 pelvic organ prolapse 9.9
28 helicobacter pylori infection 9.9
29 crohn's disease 9.9
30 inflammatory bowel disease 9.9
31 filamentary keratitis 9.9 MUC4 MUC5AC
32 mucinous tubular and spindle renal cell carcinoma 9.9 MUC2 MUC4
33 gastrointestinal system disease 9.9 ALB MUC2
34 limbal stem cell deficiency 9.9 MUC4 MUC5AC
35 cystadenoma 9.9 MUC2 MUC4
36 bronchiolo-alveolar adenocarcinoma 9.8 MUC2 MUC4
37 polyposis, skin pigmentation, alopecia, and fingernail changes 9.8 ALB MUC2 MUC5AC
38 otitis media 9.8 ALB MUC2 MUC5AC
39 barrett esophagus 9.7 MUC2 MUC5AC
40 bile duct mucoepidermoid carcinoma 9.6 MUC2 MUC4 MUC5AC
41 mucoepidermoid carcinoma 9.6 MUC2 MUC4 MUC5AC
42 chronic ethmoiditis 9.6 MUC2 MUC4 MUC5AC
43 ethmoid sinusitis 9.6 MUC2 MUC4 MUC5AC
44 intrahepatic cholangiocarcinoma 9.6 MUC2 MUC4 MUC5AC
45 cholangiocarcinoma 9.6 MUC2 MUC4 MUC5AC
46 pancreas adenocarcinoma 9.6 MUC2 MUC4 MUC5AC
47 pancreatic cancer 9.3 MUC2 MUC4 MUC5AC
48 colorectal cancer 1 9.3 MUC2 MUC3A MUC4 MUC5AC

Graphical network of the top 20 diseases related to Cap Polyposis:



Diseases related to Cap Polyposis

Symptoms & Phenotypes for Cap Polyposis

Human phenotypes related to Cap Polyposis:

60 33 (show all 8)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 colorectal polyposis 60 33 obligate (100%) Obligate (100%) HP:0200063
2 constipation 60 33 hallmark (90%) Very frequent (99-80%) HP:0002019
3 abdominal pain 60 33 hallmark (90%) Very frequent (99-80%) HP:0002027
4 hematochezia 60 33 hallmark (90%) Very frequent (99-80%) HP:0002573
5 chronic atrophic gastritis 60 33 hallmark (90%) Very frequent (99-80%) HP:0002582
6 weight loss 60 33 frequent (33%) Frequent (79-30%) HP:0001824
7 abdominal distention 60 33 frequent (33%) Frequent (79-30%) HP:0003270
8 diarrhea 60 Frequent (79-30%)

Drugs & Therapeutics for Cap Polyposis

Search Clinical Trials , NIH Clinical Center for Cap Polyposis

Genetic Tests for Cap Polyposis

Anatomical Context for Cap Polyposis

MalaCards organs/tissues related to Cap Polyposis:

42
Colon

Publications for Cap Polyposis

Articles related to Cap Polyposis:

(show top 50) (show all 53)
# Title Authors Year
1
Cap polyposis in children: case report and literature review. ( 30426196 )
2019
2
Successful laparoscopic resection for cap polyposis: case report, literature review. ( 29971597 )
2018
3
Polypectomy for Recurrent Inflammatory Cap Polyposis Combined with Argon Plasma Coagulation. ( 29774225 )
2018
4
Dysbiosis-Associated Polyposis of the Colon-Cap Polyposis. ( 29867933 )
2018
5
A Case of Cap Polyposis with Epidermal Nevus in an Infant. ( 28378565 )
2017
6
Cap polyposis refractory to<i>Helicobacter pylori</i>eradication treated with endoscopic submucosal dissection. ( 29085564 )
2017
7
Protein-losing pseudomembranous colitis with cap polyposis-like features. ( 28522919 )
2017
8
Cap Polyposis Masquerading as Inflammatory Bowel Disease in a Child. ( 27437929 )
2016
9
Education and imaging. Gastrointestinal: multiple inflammatory myoglandular polyps in a single patient. ( 25619232 )
2015
10
Inflammatory myoglandular polyps of the rectum. ( 25686710 )
2015
11
A case of cap polyposis remission by betamethasone enema after antibiotics therapy including Helicobacter pylori eradication. ( 24949613 )
2014
12
Polypectomy to eradicate cap polyposis with protein-losing enteropathy. ( 25287098 )
2014
13
Cap polyposis mistaken for Crohn's disease: case report and review of literature. ( 22766527 )
2013
14
Cap-polyposis-like gastropathy with hypoproteinemia treated with H. pylori eradication. ( 24088754 )
2013
15
Nine-year follow-up from onset to spontaneous complete remission of cap polyposis. ( 23370743 )
2013
16
Cap polyposis: a rare cause of rectal bleeding in children. ( 23864782 )
2013
17
Rectal cap polyposis masquerading as ulcerative colitis with pseudopolyposis and presenting as chronic anemia: a case study with review of literature. ( 23828750 )
2013
18
Cap polyposis and colitis cystica profunda: a rare association. ( 24118052 )
2013
19
Inflammatory cap polyposis in a 42-year-old male. ( 23416507 )
2013
20
Long-term outcome of cap polyposis, with special reference to the effects of steroid therapy. ( 22078102 )
2012
21
Successful management of cap polyposis with eradication of Helicobacter pylori relapsing 15 years after remission on steroid therapy. ( 22333383 )
2012
22
Unusual colon polyps. Diagnosis: Cap polyposis. ( 21878333 )
2011
23
Cap polyposis with protein-losing enteropathy. ( 21869875 )
2011
24
Can the stomach be a target of cap polyposis? ( 20405375 )
2010
25
Inflammatory myoglandular polyps: a case series of four patients and review of the literature. ( 20396388 )
2010
26
Inflammatory myoglandular polyps causing hematochezia. ( 20479930 )
2010
27
Remission of cap polyposis maintained for more than three years after infliximab treatment. ( 20431770 )
2009
28
Cap polyposis (CP) which relapsed after remission by avoiding straining at defecation, and was cured by Helicobacter pylori eradication therapy. ( 19952483 )
2009
29
Hypoalbuminaemia and colonic polyps: a case of protein-losing enteropathy with cap polyposis? ( 17847696 )
2007
30
Pedunculated cap polyps preceding the development of cap polyposis: case report. ( 15729261 )
2005
31
Rectal prolapse and cap polyposis: the missing link. ( 15785885 )
2005
32
Cap polyposis: an inflammatory disorder or a spectrum of mucosal prolapse syndrome? ( 16099801 )
2005
33
Confined progression of cap polyposis along the anastomotic line, implicating the role of inflammatory responses in the pathogenesis. ( 16111972 )
2005
34
Infliximab failure in cap polyposis. ( 15647206 )
2005
35
Successful treatment of cap polyposis with infliximab. ( 15188181 )
2004
36
Possible relationship between Helicobacter pylori infection and cap polyposis of the colon. ( 15610079 )
2004
37
Cap polyposis: further experience and review. ( 15164251 )
2004
38
Spontaneous resolution of cap polyposis: case report. ( 12665781 )
2003
39
Gastrointestinal: cap polyposis. ( 12753160 )
2003
40
Does metronidazole cure cap polyposis by its antiinflammatory actions instead of by its antibiotic action? A case study. ( 12141801 )
2002
41
Cap polyposis cured by Helicobacter pylori eradication therapy. ( 12108681 )
2002
42
Proximal extension of cap polyposis confirmed by colonoscopy. ( 11522989 )
2001
43
Asymptomatic cap polyposis from the sigmoid colon to the cecum. ( 11677493 )
2001
44
Cap polyposis of the colon and rectum: an analysis of endoscopic findings. ( 11293761 )
2001
45
A case of &amp;quot;cap polyposis&amp;quot;-like lesion associated with ulcerative colitis: is this a case of cap polyposis? ( 11095366 )
2000
46
Features of cap polyposis by magnifying colonoscopy. ( 11115917 )
2000
47
Successful treatment of cap polyposis by avoidance of intraluminal trauma: clues to pathogenesis. ( 10950064 )
2000
48
A case of cap polyposis investigated by scintigraphy with human serum albumin labeled with Tc-99m DTPA. ( 9712385 )
1998
49
Abnormal mucus in cap polyposis. ( 9518233 )
1998
50
Protein-losing enteropathy from cap polyposis. ( 7491082 )
1995

Variations for Cap Polyposis

Expression for Cap Polyposis

Search GEO for disease gene expression data for Cap Polyposis.

Pathways for Cap Polyposis

GO Terms for Cap Polyposis

Cellular components related to Cap Polyposis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.26 ALB MUC3A MUC4 MUC5AC
2 Golgi lumen GO:0005796 8.92 MUC2 MUC3A MUC4 MUC5AC

Biological processes related to Cap Polyposis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 stimulatory C-type lectin receptor signaling pathway GO:0002223 9.26 MUC2 MUC3A MUC4 MUC5AC
2 maintenance of gastrointestinal epithelium GO:0030277 9.16 MUC2 MUC4
3 O-glycan processing GO:0016266 8.92 MUC2 MUC3A MUC4 MUC5AC

Molecular functions related to Cap Polyposis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular matrix structural constituent GO:0005201 8.96 MUC3A MUC5AC
2 extracellular matrix constituent, lubricant activity GO:0030197 8.62 MUC3A MUC4

Sources for Cap Polyposis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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