MCID: CPL006
MIFTS: 55

Capillary Hemangioma

Categories: Cardiovascular diseases, Genetic diseases, Skin diseases

Aliases & Classifications for Capillary Hemangioma

MalaCards integrated aliases for Capillary Hemangioma:

Name: Capillary Hemangioma 12 15
Strawberry Nevus of Skin 12 74
Infantile Hemangioma 12 38
Cellular Hemangioma of Infancy 12
Congenital Vascular Hamartoma 12
Congenital Vascular Naevus 12
Strawberry Haemangioma 12
Hemangioma, Cavernous 74
Hemangioma, Capillary 45
Hemangioma Capillary 56
Juvenile Hemangioma 12
Strawberry Nevus 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2725
KEGG 38 H01482
MeSH 45 D018324
NCIt 51 C7457
SNOMED-CT 69 56975005 83343001
ICD10 34 Q82.5

Summaries for Capillary Hemangioma

MalaCards based summary : Capillary Hemangioma, also known as strawberry nevus of skin, is related to pyogenic granuloma and hemangioma, capillary infantile. An important gene associated with Capillary Hemangioma is PECAM1 (Platelet And Endothelial Cell Adhesion Molecule 1), and among its related pathways/superpathways are VEGF signaling pathway and ERK Signaling. The drugs Timolol and Propranolol have been mentioned in the context of this disorder. Affiliated tissues include skin, endothelial and spinal cord, and related phenotypes are cardiovascular system and cellular

Wikipedia : 77 A capillary hemangioma (also known as an Infantile hemangioma,Strawberry hemangioma, and Strawberry... more...

Related Diseases for Capillary Hemangioma

Diseases in the Capillary Hemangioma family:

Hemangioma, Capillary Infantile

Diseases related to Capillary Hemangioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 153)
# Related Disease Score Top Affiliating Genes
1 pyogenic granuloma 33.6 TEK VEGFA
2 hemangioma, capillary infantile 32.8 ANTXR1 KDR
3 hemangioendothelioma 30.5 KDR PECAM1
4 kaposiform hemangioendothelioma 30.2 GNA14 KDR PECAM1
5 arteriovenous malformation 29.9 RASA1 VEGFA
6 lymphangioma 29.8 KDR VEGFA
7 hemangioblastoma 29.8 SLC2A1 VEGFA VHL
8 hemangioma 29.7 ANTXR1 FLT1 KDR PECAM1 SLC2A1 TEK
9 clear cell renal cell carcinoma 29.4 KDR SLC2A1 VEGFA VHL
10 renal cell carcinoma, nonpapillary 29.4 FLT1 KDR VEGFA VHL
11 exudative vitreoretinopathy 1 29.3 FLT1 KDR TEK VEGFA
12 angiosarcoma 28.9 FLT1 KDR PECAM1 TEK VEGFA
13 breast capillary hemangioma 12.3
14 angioma, tufted 11.5
15 capillary malformations, congenital 11.4
16 cerebral cavernous malformations 11.2
17 non-involuting congenital hemangioma 11.1
18 retinal detachment 10.3
19 pancreatic serous cystadenoma 10.3 VEGFA VHL
20 critical limb ischemia 10.2 TEK VEGFA
21 intramuscular hemangioma 10.2 SLC2A1 TEK
22 chronic myocardial ischemia 10.2 TEK VEGFA
23 pulmonary vein stenosis 10.2 KDR PECAM1
24 hydrocele 10.2 PECAM1 VEGFA
25 renal pelvis carcinoma 10.2 SLC2A1 VEGFA
26 cardiovascular organ benign neoplasm 10.2 SLC2A1 TEK
27 benign perivascular tumor 10.2 SLC2A1 TEK
28 retinal hemangioblastoma 10.1 VEGFA VHL
29 drug-induced lupus erythematosus 10.1 KDR VEGFA
30 von hippel-lindau syndrome 10.1
31 angiomatous meningioma 10.1 KDR VEGFA
32 leukostasis 10.1 KDR VEGFA
33 diabetic macular edema 10.1 TEK VEGFA
34 coats disease 10.1 KDR VEGFA
35 juvenile nasopharyngeal angiofibroma 10.1 PECAM1 VEGFA
36 astigmatism 10.1
37 suppression amblyopia 10.1
38 amblyopia 10.1
39 central nervous system hemangioma 10.1
40 radiation proctitis 10.0 KDR PECAM1 VEGFA
41 kidney cancer 10.0 KDR VEGFA VHL
42 congenital lipomatous overgrowth, vascular malformations, and epidermal nevi 10.0 PECAM1 RASA1 SLC2A1
43 limb ischemia 10.0 KDR TEK VEGFA
44 hemangioma-thrombocytopenia syndrome 10.0
45 neuroblastoma 10.0
46 hydrocephalus 10.0
47 cavernous hemangioma 10.0
48 glomeruloid hemangioma 10.0 FLT1 VEGFA
49 epileptic encephalopathy, childhood-onset 9.9 KDR VEGFA
50 microcystic meningioma 9.9 FLT1 VEGFA

Graphical network of the top 20 diseases related to Capillary Hemangioma:



Diseases related to Capillary Hemangioma

Symptoms & Phenotypes for Capillary Hemangioma

MGI Mouse Phenotypes related to Capillary Hemangioma:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.03 ANTXR1 FLT1 KDR PECAM1 RASA1 TEK
2 cellular MP:0005384 10.01 ANTXR1 FLT1 KDR PECAM1 RASA1 SLC2A1
3 embryo MP:0005380 9.87 FLT1 KDR RASA1 SLC2A1 TEK VEGFA
4 growth/size/body region MP:0005378 9.86 ANTXR1 FLT1 KDR RASA1 SLC2A1 TEK
5 craniofacial MP:0005382 9.77 ANTXR1 KDR RASA1 VEGFA VHL
6 muscle MP:0005369 9.7 FLT1 KDR PECAM1 RASA1 TEK VEGFA
7 no phenotypic analysis MP:0003012 9.35 ANTXR1 KDR RASA1 SLC2A1 VEGFA
8 skeleton MP:0005390 9.1 ANTXR1 KDR PECAM1 RASA1 VEGFA VHL

Drugs & Therapeutics for Capillary Hemangioma

Drugs for Capillary Hemangioma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 132)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Timolol Approved Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 26839-75-8 33624 5478
2
Propranolol Approved, Investigational Phase 2, Phase 3,Phase 3,Phase 1,Not Applicable 525-66-6 4946
3
Atenolol Approved Phase 3 29122-68-7 2249
4
Nadolol Approved Phase 3,Phase 2 42200-33-9 39147
5
Benzocaine Approved, Investigational Phase 3 94-09-7, 1994-09-7 2337
6
tannic acid Approved Phase 3 1401-55-4
7
Acebutolol Approved, Investigational Phase 3 37517-30-9 1978
8
SB-649868 Experimental, Investigational Phase 3,Phase 2,Phase 1,Not Applicable 110-16-7, 110-17-8 444972
9 Adrenergic Antagonists Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
10 Adrenergic beta-Antagonists Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
11 Anti-Arrhythmia Agents Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
12 Neurotransmitter Agents Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
13 Adrenergic Agents Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
14 Antihypertensive Agents Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
15 Pharmaceutical Solutions Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
16 Ophthalmic Solutions Phase 3,Not Applicable
17 Vasodilator Agents Phase 2, Phase 3,Phase 3,Phase 1,Not Applicable
18 Sympatholytics Phase 3,Phase 2
19 Autonomic Agents Phase 3,Phase 2
20 Adrenergic beta-1 Receptor Antagonists Phase 3
21 Peripheral Nervous System Agents Phase 3,Phase 2
22 Brimonidine Tartrate Phase 3 70359-46-5
23 Adrenergic Agonists Phase 3
24 Adrenergic alpha-2 Receptor Agonists Phase 3
25 Adrenergic alpha-Agonists Phase 3
26 Sympathomimetics Phase 3
27
Bosentan Approved, Investigational Phase 2 147536-97-8 104865
28 Strawberry Approved Phase 2
29
Prednisone Approved, Vet_approved Phase 2,Not Applicable 53-03-2 5865
30
Imiquimod Approved, Investigational Phase 2,Not Applicable 99011-02-6 57469
31
Prednisolone Approved, Vet_approved Phase 2 50-24-8 5755
32
Prednisolone phosphate Approved, Vet_approved Phase 2 302-25-0
33
Methylprednisolone Approved, Vet_approved Phase 2 83-43-2 6741
34
Methylprednisolone hemisuccinate Approved Phase 2 2921-57-5
35
Everolimus Approved Phase 2,Phase 1,Not Applicable 159351-69-6 6442177 70789204
36
Sirolimus Approved, Investigational Phase 2,Phase 1,Not Applicable 53123-88-9 46835353 6436030 5284616
37
Miconazole Approved, Investigational, Vet_approved Phase 2,Phase 1,Not Applicable 22916-47-8 4189
38
Bleomycin Approved, Investigational Phase 2 11056-06-7 5360373
39
Ranibizumab Approved Phase 1, Phase 2 347396-82-1 459903
40
Cyclophosphamide Approved, Investigational Phase 1, Phase 2 6055-19-2, 50-18-0 2907
41
Ranitidine Approved Phase 2 66357-59-3, 66357-35-5 3001055
42
Vincristine Approved, Investigational Phase 2 2068-78-2, 57-22-7 5978
43
Histidine Approved, Nutraceutical Phase 1, Phase 2 71-00-1 6274
44
Prednisolone hemisuccinate Experimental Phase 2 2920-86-7
45 Endothelin Receptor Antagonists Phase 2
46 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 2,Not Applicable
47 glucocorticoids Phase 2,Not Applicable
48 Antineoplastic Agents, Hormonal Phase 2,Not Applicable
49 Hormone Antagonists Phase 2,Not Applicable
50 Hormones Phase 2,Not Applicable

Interventional clinical trials:

(show top 50) (show all 84)
# Name Status NCT ID Phase Drugs
1 A Pilot Study of Hemoporfin PDT in Children With Port-wine Stain Recruiting NCT03125057 Phase 4 Hemoporfin PDT
2 Postmarketing Safety Study of Hemoporfin in Patients With Port Wine Stain Recruiting NCT03181984 Phase 4 Hemoporfin
3 Treatment of Port Wine Stains in Children With Pulsed Dye Laser and Timolol Gel Unknown status NCT01272609 Phase 3 Timolol + LCP
4 Topical Timolol for Superficial Infantile Hemangioma Unknown status NCT01685398 Phase 3 0.5% timolol maleate eye drop;Normal saline
5 Study to Demonstrate the Efficacy and Safety of Propranolol Oral Solution in Infants With Proliferating Infantile Hemangiomas Requiring Systemic Therapy Completed NCT01056341 Phase 2, Phase 3 Propranolol;Placebo
6 Efficacy and Safety of Propranolol Versus Atenolol on the Proliferative Phase of Infantile Hemangioma Completed NCT02342275 Phase 3 Propranolol;Atenolol
7 Nadolol Versus Propranolol in Children With Infantile Hemangiomas Recruiting NCT02505971 Phase 3 Nadolol;Propranolol
8 Comparative Study to Evaluate the Effectiveness of Atenolol and Propranolol in the Treatment of Infantile Hemangiomas Recruiting NCT03237637 Phase 3 oral propranolol;oral atenolol
9 Onreltea (Brimonidine) Gel In Pediatric Patients With Capillary Malformations Recruiting NCT02764411 Phase 3 Brimonidine 0.33% gel
10 MELABLOCK: A Clinical Trial on the Efficacy and Safety of Propranolol 80 mg in Melanoma Patients Not yet recruiting NCT02962947 Phase 2, Phase 3 Propranolol;Placebo
11 Effectiveness and Safety of Intense Pulsed Light in Patients With Meibomian Gland Dysfunction Not yet recruiting NCT03518398 Phase 3
12 Propranolol in Capillary Hemangiomas Terminated NCT00744185 Phase 2, Phase 3 propranolol treatment;placebo treatment
13 Efficacy and Safety of Propranolol Versus Acebutolol on the Proliferative Phase of Infantile Hemangioma Terminated NCT01743885 Phase 3 Acebutolol;Propanolol
14 Study in Infants With Infantile Hemangioma to Compare Propranolol Gel to Placebo Completed NCT01512173 Phase 2 propranolol gel;Placebo
15 Treatment of Resistant Port-wine Stains With Bosentan and Pulsed Dye Laser: a Pilot Study Completed NCT02317679 Phase 2 Bosentan
16 Nadolol for Proliferating Infantile Hemangiomas Completed NCT01010308 Phase 2 Nadolol
17 Topical Timolol Gel for the Treatment of Infantile Hemangiomas Completed NCT02145884 Phase 2 timolol maleate 0.5% gel
18 Topical Timolol for Infantile Hemangioma in Early Proliferative Phase Completed NCT02731287 Phase 2 Timolol;Placebo
19 Comparative Study of the Use of Beta Blocker and Oral Corticosteroid in the Treatment of Infantile Hemangioma Completed NCT01072045 Phase 2 Propranolol;Prednisone
20 Measurement Skin Temperature During Pulsed Laser Exposure Completed NCT00540917 Phase 2
21 A Phase II Study of Imiquimod 5 % Cream for the Treatment of Hemangioma in Infancy Completed NCT00601016 Phase 2 Imiquimod 5% cream
22 Efficacy, Safety and Pharmacokinetics of Topical Timolol in Infants With Infantile Hemangioma (IH) Recruiting NCT02913612 Phase 2 0.25% Timolol Maleate Gel Forming Solution;0.5% Timolol Maleate Gel Forming Solution
23 Electrosclerotherapy for Capillary Malformations Recruiting NCT02883023 Phase 2 Intralesional bleomycin injection
24 A Phase I/II Trial for Intravitreous Treatment of Severe Ocular Von Hippel-Lindau Disease Using a Combination of the PDGF Antagonist E10030 and the VEGF Antagonist Ranibizumab Active, not recruiting NCT02859441 Phase 1, Phase 2 Ranibizumab;E10030
25 Dose-Finding of Propranolol in Combination With Metronomic Fixed Oral Cyclophosphamide Based on Bivariate Efficacy-tolerability Outcome in Patients With Locally Advanced or Metastatic Angiosarcoma: A Collaborative and Innovative Phase I-II Sequential Trial by the French Sarcoma Group (GSF/GETO) Not yet recruiting NCT02732678 Phase 1, Phase 2 PROPRANOLOL
26 The Effects of Aldara as an Adjunct to Laser Treatment Terminated NCT00979550 Phase 2 Imiquimod;non-medicated petroleum cream
27 Corticosteroids With Placebo Versus Corticosteroids With Propranolol Treatment of Infantile Hemangiomas (IH) Terminated NCT01074437 Phase 2 Prednisolone (Corticosteroid);Propranolol;Placebo
28 Clinical Trial of Vincristine vs. Prednisolone for Treatment of Complicated Hemangiomas Terminated NCT00555464 Phase 2 Vincristine;Prednisone
29 Combined Use of Pulsed Dye Laser and Topical Antiangiogenic Agents for Treatment of Port Wine Stain Birthmarks Withdrawn NCT00969397 Phase 1, Phase 2 Topical Antiangiogenic
30 Timolol Option for Ulcerated Hemangiomas (TOUCH Trial) Withdrawn NCT01408056 Phase 2 Timolol 0.5% Gel Forming Solution (GFS);Mupirocin 2% Ointment
31 Adjunctive Everolimus (RAD 001) Therapy for Epilepsy in Children With Sturge-Weber Syndrome (SWS) Withdrawn NCT01997255 Phase 2 Everolimus
32 A Randomized Trial to Study Combined Pulsed Dye Laser and Rapamycin Treatment of Port Wine Stain Birthmarks. Completed NCT00800722 Phase 1 Rapamycin Treatment of Port Wine Stain
33 Novel Treatment for Port Wine Stain Birthmarks Completed NCT01924273 Phase 1 Talaporfin sodium
34 A Randomized Trial to Study Combined Pulsed Dye Laser and Rapamycin Treatment of Port Wine Stain Birthmarks. Completed NCT00830466 Phase 1 Laser and rapamycin versus laser alone
35 Pulsed Dye Laser Treatment of Port Wine Stain Birthmarks: Comparison of 577 nm Versus 595 nm Wavelengths Completed NCT00573729 Phase 1
36 Treatment of Vascular Lesions With a Tandem 532/1064 nm Laser Completed NCT00585338 Phase 1
37 Optical Clearing of the Skin in Conjunction With Laser Treatments Completed NCT00580736 Phase 1
38 Timolol for the Prevention of Proliferation of Infantile Hemangioma (TiPPIH Trial) Terminated NCT01434849 Phase 1 topical 0.5% Timolol maleate;Control (placebo) group
39 Combined Alexandrite and Pulsed Dye Laser Treatment of Port Wine Stain Birthmarks Withdrawn NCT00580944 Phase 1
40 Combined Pulsed Dye Laser and Topical Ranibizumab for Treatment of Port Wine Stain Birthmarks Withdrawn NCT00667472 Phase 1 Ranibizumab
41 Pilot Study on the Use of the Matrix Radiofrequencyfor Treatment of Port Wine Stain Birthmarks Withdrawn NCT01166919 Phase 1
42 The Angioma's Treatment Evaluation With Laser Doppler Imaging (LDI) Unknown status NCT01759082
43 Evaluation and Optimization of the Technical and Clinical Performance of the Lumenis ONE Platform Unknown status NCT00247299 Not Applicable
44 Clinical Characteristics of Lip Hemangiomas Unknown status NCT02351245
45 A Prospective Study Comparing the Incidence of Infantile Hemangiomas Following Normal Pregnancies Versus Pregnancies Complicated by Placental Abnormalities Unknown status NCT00490607
46 Oral Propranolol Improve Retinopathy of Prematurity Outcomes in Very Preterm Infants Unknown status NCT02977000 Not Applicable Propranolol
47 Monitoring the Response of Port Wine Stain Birthmarks to Laser Therapy With Wide-field Functional Imaging Technologies Completed NCT01333553
48 Dynamic Epidermal Cooling During Pulsed Dye Laser Treatment of Port Wine Stain Birthmark at High Fluences Completed NCT00540371
49 Port Wine Stains Treatment Matrix RF Study Completed NCT01101360 Not Applicable
50 Combined Photodynamic and Pulsed Dye Laser Treatment of Port Wine Stains Completed NCT00556946 Not Applicable Combined Photodynamic & Pulsed Dye Laser Treatment

Search NIH Clinical Center for Capillary Hemangioma

Cochrane evidence based reviews: hemangioma, capillary

Genetic Tests for Capillary Hemangioma

Anatomical Context for Capillary Hemangioma

MalaCards organs/tissues related to Capillary Hemangioma:

42
Skin, Endothelial, Spinal Cord, Lung, Testis, Bone, Eye

Publications for Capillary Hemangioma

Articles related to Capillary Hemangioma:

(show top 50) (show all 872)
# Title Authors Year
1
Case of multiple disseminated cutaneous lobular capillary hemangioma that developed while taking oral contraceptive pills. ( 30628110 )
2019
2
"Intramedullary capillary hemangioma presenting with hydrocephalus and spastic paraparesis in a two-month-old infant". ( 30685376 )
2019
3
Spinal epidural capillary hemangioma: case report and review of the literature. ( 30829069 )
2019
4
Lobular Capillary Hemangioma in Post-Pneumonectomy Bronchial Stump. ( 30850193 )
2019
5
High-frequency ultrasonography and contrast-enhanced ultrasound for the evaluation of testicular capillary hemangioma: A case report. ( 30882650 )
2019
6
The Use of OCT and OCT Angiography in Detecting an Atypical Case of Retinal Capillary Hemangioma. ( 30893462 )
2019
7
Itraconazole induces regression of infantile hemangioma via down-regulation of the PDGF-D/PI3K/Akt/mTOR pathway. ( 30690033 )
2019
8
Late ulceration of residual abortive infantile hemangioma: a rare complication. ( 30719710 )
2019
9
Associations between short-term efficacy and clinical characteristics of infantile hemangioma treated by propranolol. ( 30732164 )
2019
10
A barrier to care: Distance traveled affects adherence to treatment and follow-up plans for patients with infantile hemangioma. ( 30762240 )
2019
11
Central Nervous System Effects of Oral Propranolol for Infantile Hemangioma: A Systematic Review and Meta-Analysis. ( 30813242 )
2019
12
Title: Intralesional Injection of Bevacizumab versus Triamcinolone acetonide in Infantile Hemangioma. ( 30835573 )
2019
13
Secondary Congenital Glaucoma Associated With Retro-orbital Infantile Hemangioma: A Masquerade Syndrome. ( 30839414 )
2019
14
Retracted: Mechanisms of Action of MicroRNAs in Infantile Hemangioma Tissue and Vascular Endothelial Cells in Different Periods. ( 30845108 )
2019
15
T3 infantile hemangioma: first case of a tumor involving epidural, intradural extramedullary, and intradural intramedullary spaces. ( 30849748 )
2019
16
The efficacy of low-dose propranolol treatment in infantile hemangioma and the results of intralesional bleomycin injection in patients unresponsive to propranolol. ( 30861274 )
2019
17
Location of infantile hemangioma is a predictor of volumetric sequelae after involution. ( 30888067 )
2019
18
Pulmonary Infantile Hemangioma Mimicking a Congenital Cystic Adenomatoid Malformation. ( 30913983 )
2019
19
Clinical and radiological outcomes of infantile hemangioma treated with oral propranolol: A long-term follow-up study. ( 30916822 )
2019
20
No Increased Risks Associated with Propranolol Treatment for Infantile Hemangioma in Preterm Infants were Identified at 3 Years of Age. ( 30618026 )
2019
21
Lobular capillary hemangioma of the mandible: A case report. ( 29704808 )
2018
22
Prolonged growth of infantile hemangioma after pulsed dye laser and oral propranolol treatment. ( 29952019 )
2018
23
Role of thrombospondin-1 and nuclear factor-kappa B signaling pathways in anti-angiogenesis of infantile hemangioma. ( 29927834 )
2018
24
Tocolysis with the I^<sub>2</sub>-sympathomimetic fenoterol does not increase the occurrence of infantile hemangioma in preterm and term infants. ( 29938346 )
2018
25
Multimodal Imaging of Optic Nerve Head Capillary Hemangioma. ( 29864074 )
2018
26
Capillary hemangioma associated with dermal atrophy masquerading as a deep fungal infection. ( 29634891 )
2018
27
Cervical corpectomy for resection of ventral intramedullary capillary hemangioma with circumferential involvement of the anterior spinal artery: case report. ( 29726799 )
2018
28
Subcutaneous Lobular Capillary Hemangioma Presenting as a Facial Mass. ( 29854524 )
2018
29
Venous outlet syndrome caused by capillary hemangioma of the subclavian vein. ( 29444598 )
2018
30
Solitary Retinal Capillary Hemangioma with Nonlipid Exudative Retinal Detachment. ( 29389404 )
2018
31
Treatment of retinal capillary hemangioma using 810 nm infrared laser. ( 29765174 )
2018
32
Curcumin induces apoptosis and inhibits proliferation in infantile hemangioma endothelial cells via downregulation of MCL-1 and HIF-1I+. ( 29443732 )
2018
33
I^-Adrenoceptor Blockade for Infantile Hemangioma Therapy: Do I^3-Adrenoceptors Play a Role? ( 29936502 )
2018
34
Long-Term Therapeutic Outcomes of Photodynamic Therapy-Based or Photocoagulation-Based Treatments on Retinal Capillary Hemangioma. ( 29068750 )
2018
35
Combined Oral and Topical Beta Blockers for the Treatment of Early Proliferative Superficial Periocular Infantile Capillary Hemangioma. ( 28991344 )
2018
36
Vascular Tumors in Infants: Case Report and Review of Clinical, Histopathologic, and Immunohistochemical Characteristics of Infantile Hemangioma, Pyogenic Granuloma, Noninvoluting Congenital Hemangioma, Tufted Angioma, and Kaposiform Hemangioendothelioma. ( 29561329 )
2018
37
Factors associated with delayed referral for infantile hemangioma necessitating propranolol. ( 29405477 )
2018
38
Capillary Hemangioma as an Unusual Cause of Doughnut Sign on Bone Scan. ( 29742594 )
2018
39
INTRAVITREAL INJECTION OF PROPRANOLOL FOR THE TREATMENT OF RETINAL CAPILLARY HEMANGIOMA IN A CASE OF VON HIPPEL-LINDAU. ( 29466252 )
2018
40
A Rare Case of Gallbladder and Common Bile Duct Benign Capillary Hemangioma in a Toddler. ( 29652727 )
2018
41
Allergic contact dermatitis caused by timolol eyedrops application for infantile hemangioma. ( 30485454 )
2018
42
A Rare Cause of Resistant Epistaxis: Lobular Capillary Hemangioma Arising from the Inferior Turbinate. ( 29988261 )
2018
43
Intramural capillary hemangioma of gallbladder artery: age-related or treatment-induced change? ( 30005393 )
2018
44
Giant congenital right atrial epithelioid-capillary hemangioma with prolonged QT interval: Case report and practical surgical treatment strategy for primary cardiac tumors in children based on 25-year review of 299 cases. ( 30030856 )
2018
45
Anesthetic implications for coexisting cardiac capillary hemangioma and multiple coronary artery to pulmonary artery fistulas. ( 30100854 )
2018
46
Unusual Cause of Pediatric Vaginal Bleeding: Infantile Capillary Hemangioma of the Cervix. ( 30107231 )
2018
47
Retinal capillary hemangioma and von Hippel-Lindau disease. ( 30139593 )
2018
48
Capillary hemangioma in the ileum: Obscure small-bowel bleeding in an elderly person. ( 30249572 )
2018
49
Solitary pulmonary capillary hemangioma: An under-recognized pulmonary lesion mimicking early lung cancer on computed tomography images. ( 30268465 )
2018
50
Solitary pulmonary capillary hemangioma: Clinicopathologic and radiologic characteristics of nine surgically resected cases. ( 30268596 )
2018

Variations for Capillary Hemangioma

Expression for Capillary Hemangioma

Search GEO for disease gene expression data for Capillary Hemangioma.

Pathways for Capillary Hemangioma

Pathways related to Capillary Hemangioma according to KEGG:

38
# Name Kegg Source Accession
1 VEGF signaling pathway hsa04370

Pathways related to Capillary Hemangioma according to GeneCards Suite gene sharing:

(show all 31)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.61 FLT1 GNA14 KDR RASA1 TEK VEGFA
2
Show member pathways
12.78 FLT1 KDR TEK VEGFA
3 12.52 FLT1 KDR RASA1 TEK VEGFA
4
Show member pathways
12.44 FLT1 KDR RASA1 TEK VEGFA
5
Show member pathways
12.21 FLT1 KDR VEGFA
6
Show member pathways
12.2 KDR RASA1 VEGFA
7
Show member pathways
12.16 FLT1 KDR RASA1 TEK
8
Show member pathways
12.02 FLT1 KDR VEGFA
9 11.94 FLT1 KDR TEK
10 11.89 FLT1 KDR TEK
11 11.86 KDR PECAM1 VEGFA
12 11.84 FLT1 KDR VEGFA
13
Show member pathways
11.75 KDR RASA1 VEGFA
14
Show member pathways
11.73 FLT1 GNA14 KDR VEGFA
15 11.65 FLT1 SLC2A1 TEK VEGFA VHL
16 11.63 FLT1 TEK VEGFA
17 11.57 FLT1 KDR PECAM1 TEK
18
Show member pathways
11.52 FLT1 KDR RASA1 VEGFA VHL
19 11.48 FLT1 KDR VEGFA
20 11.39 SLC2A1 VEGFA VHL
21
Show member pathways
11.27 KDR VEGFA
22 11.24 FLT1 KDR VEGFA
23 11.2 RASA1 TEK
24 11.19 SLC2A1 VEGFA
25 11.02 FLT1 VEGFA
26 10.88 FLT1 KDR VEGFA
27 10.82 FLT1 GNA14 KDR TEK
28 10.75 VEGFA VHL
29 10.64 FLT1 KDR TEK VEGFA
30 10.55 FLT1 KDR SLC2A1 VEGFA VHL
31 10.1 RASA1 TEK

GO Terms for Capillary Hemangioma

Cellular components related to Capillary Hemangioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytoplasm GO:0005737 9.81 FLT1 KDR MAP7D3 PECAM1 RASA1 SLC2A1
2 receptor complex GO:0043235 9.13 FLT1 KDR TEK
3 membrane raft GO:0045121 8.92 KDR PECAM1 SLC2A1 TEK

Biological processes related to Capillary Hemangioma according to GeneCards Suite gene sharing:

(show all 31)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.82 FLT1 KDR TEK
2 positive regulation of cell migration GO:0030335 9.81 FLT1 KDR VEGFA
3 positive regulation of protein phosphorylation GO:0001934 9.78 KDR TEK VEGFA
4 peptidyl-tyrosine phosphorylation GO:0018108 9.77 FLT1 KDR TEK
5 response to hypoxia GO:0001666 9.77 SLC2A1 TEK VEGFA
6 protein autophosphorylation GO:0046777 9.76 FLT1 KDR TEK
7 regulation of cell shape GO:0008360 9.74 KDR RASA1 VEGFA
8 transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 9.7 FLT1 KDR TEK
9 positive regulation of endothelial cell proliferation GO:0001938 9.69 KDR TEK VEGFA
10 positive regulation of phosphatidylinositol 3-kinase signaling GO:0014068 9.67 FLT1 KDR TEK
11 substrate adhesion-dependent cell spreading GO:0034446 9.65 ANTXR1 TEK
12 vascular endothelial growth factor receptor signaling pathway GO:0048010 9.65 FLT1 KDR VEGFA
13 positive regulation of cell migration involved in sprouting angiogenesis GO:0090050 9.64 KDR VEGFA
14 negative regulation of endothelial cell apoptotic process GO:2000352 9.63 KDR TEK
15 positive regulation of phosphatidylinositol 3-kinase activity GO:0043552 9.63 FLT1 TEK
16 sprouting angiogenesis GO:0002040 9.62 TEK VEGFA
17 blood vessel morphogenesis GO:0048514 9.62 FLT1 RASA1
18 positive regulation of angiogenesis GO:0045766 9.62 FLT1 KDR TEK VEGFA
19 regulation of transcription from RNA polymerase II promoter in response to hypoxia GO:0061418 9.61 VEGFA VHL
20 vasculogenesis GO:0001570 9.61 KDR RASA1 VEGFA
21 cell migration involved in sprouting angiogenesis GO:0002042 9.58 KDR VEGFA
22 positive regulation of endothelial cell migration GO:0010595 9.58 KDR TEK VEGFA
23 positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 9.56 FLT1 VEGFA
24 positive regulation of MAPK cascade GO:0043410 9.55 FLT1 KDR
25 negative regulation of apoptotic process GO:0043066 9.55 KDR RASA1 TEK VEGFA VHL
26 positive regulation of positive chemotaxis GO:0050927 9.54 KDR VEGFA
27 cellular response to vascular endothelial growth factor stimulus GO:0035924 9.54 FLT1 KDR VEGFA
28 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway GO:0038033 9.46 KDR VEGFA
29 positive regulation of focal adhesion assembly GO:0051894 9.43 KDR TEK VEGFA
30 vascular endothelial growth factor signaling pathway GO:0038084 9.13 FLT1 KDR VEGFA
31 angiogenesis GO:0001525 9.02 FLT1 KDR PECAM1 TEK VEGFA

Molecular functions related to Capillary Hemangioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein tyrosine kinase activity GO:0004713 9.5 FLT1 KDR TEK
2 vascular endothelial growth factor-activated receptor activity GO:0005021 9.26 FLT1 KDR
3 transmembrane receptor protein tyrosine kinase activity GO:0004714 9.13 FLT1 KDR TEK
4 transmembrane signaling receptor activity GO:0004888 8.85 ANTXR1
5 growth factor binding GO:0019838 8.8 FLT1 KDR TEK

Sources for Capillary Hemangioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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