MCID: CPL004
MIFTS: 29

Caplan's Syndrome

Categories: Bone diseases, Respiratory diseases

Aliases & Classifications for Caplan's Syndrome

MalaCards integrated aliases for Caplan's Syndrome:

Name: Caplan's Syndrome 12 77 15 17
Caplan Syndrome 12 45 74
Rheumatoid Pneumoconiosis 12
Caplan's Disease 12
Caplans Syndrome 12

Classifications:



External Ids:

Disease Ontology 12 DOID:10326
MeSH 45 D002205
UMLS 74 C0006915

Summaries for Caplan's Syndrome

Disease Ontology : 12 A pneumoconiosis that results in humans that also have rheumatoid arthritis.

MalaCards based summary : Caplan's Syndrome, also known as caplan syndrome, is related to pneumoconiosis and rheumatoid arthritis. An important gene associated with Caplan's Syndrome is FAS (Fas Cell Surface Death Receptor), and among its related pathways/superpathways are Allograft rejection and Direct p53 effectors. Affiliated tissues include heart, eye and bone.

Wikipedia : 77 Caplan''s syndrome (or Caplan disease or rheumatoid pneumoconiosis) is a combination of rheumatoid... more...

Related Diseases for Caplan's Syndrome

Graphical network of the top 20 diseases related to Caplan's Syndrome:



Diseases related to Caplan's Syndrome

Symptoms & Phenotypes for Caplan's Syndrome

Drugs & Therapeutics for Caplan's Syndrome

Search Clinical Trials , NIH Clinical Center for Caplan's Syndrome

Cochrane evidence based reviews: caplan syndrome

Genetic Tests for Caplan's Syndrome

Anatomical Context for Caplan's Syndrome

MalaCards organs/tissues related to Caplan's Syndrome:

42
Heart, Eye, Bone, T Cells

Publications for Caplan's Syndrome

Articles related to Caplan's Syndrome:

(show all 33)
# Title Authors Year
1
A case of Caplan syndrome in a recently diagnosed patient with silicosis: A case report. ( 30023036 )
2018
2
Rheumatoid pneumoconiosis (Caplan's syndrome). ( 20493416 )
2010
3
Severe mitral regurgitation in a patient with a bluish right sclera: an 'extension' of Caplan's syndrome to the heart and eye. ( 19237064 )
2009
4
Rheumatoid pneumoconiosis (Caplan's syndrome) with a classical presentation. ( 19820822 )
2009
5
Parkinsonism in Caplan's syndrome. ( 16688603 )
2006
6
Computed tomography findings of Caplan syndrome. ( 14501367 )
2003
7
Caplan's syndrome. ( 1810363 )
1991
8
Caplan's syndrome. ( 2661027 )
1989
9
HLA-A, B and DR antigens and properdin factor B allotypes in Caplan's syndrome. ( 6577907 )
1983
10
HLA-A and B antigen frequencies in Welsh coalworkers with pneumoconiosis and Caplan's syndrome. ( 91226 )
1979
11
Prevalence of rheumatoid pneumoconiosis (Caplan's syndrome) in metal miners. ( 455199 )
1979
12
Rheumatoid "pneumoconiosis" (Caplan's syndrome) in an asbestos worker: a 17 years' follow-up. ( 483218 )
1979
13
Pulmonary function in coal workers with Caplan's syndrome and non-rheumatoid complicated pneumosoniosis. ( 746502 )
1978
14
Pneumoconiosis and Rheumatoid arthritis (Caplan's syndrome). ( 326283 )
1977
15
Caplan's syndrome in miners. ( 413171 )
1977
16
Rheumatoid pericarditis possibly associated with Caplan's syndrome. ( 1049236 )
1976
17
Caplan's syndrome - a clinical study of 13 cases. ( 1221495 )
1975
18
Caplan's syndrome in association with asbestosis. Report of a case. ( 5161827 )
1971
19
Caplan's syndrome. ( 6081295 )
1967
20
Caplan's syndrome. ( 5937655 )
1966
21
CAPLAN'S SYNDROME IN A SLATE MINER. ( 14114886 )
1964
22
Rheumatoid pneumoconiosis. A case of Caplan's syndrome in a chalk-mine worker. ( 13928349 )
1963
23
A broader concept of Caplan's syndrome related to rheumatoid factors. ( 13876317 )
1962
24
Serum protein changes in Caplan's syndrome. ( 13900595 )
1962
25
Rheumatoid pneumoconiosis (Caplan's syndrome). A discussion of the disease and a report of a case in a European Witwatersrand gold miner. ( 13692590 )
1961
26
Rheumatoid pneumoconiosis (Caplan's syndrome) in an asbestos worker. ( 13920165 )
1961
27
Caplan's syndrome, An interesting clinico-pathological occurrence. ( 14475979 )
1961
28
A case of Caplan's syndrome in a roof tile maker. ( 14400322 )
1960
29
Pneumoconiosis in makers of artificial grinding wheels, including a case of Caplan's syndrome. ( 14434374 )
1960
30
Rheumatoid disease and pneumoconiosis (Caplan's syndrome). ( 13807528 )
1959
31
Caplan's syndrome: a perplexing pneumoconiosis with rheumatoid arthritis. ( 13559659 )
1958
32
A case of Caplan's syndrome in a boiler-scaler. ( 13580970 )
1958
33
Pathological studies of modified pneumoconiosis in coal-miners with rheumatoid arthritis; Caplan's syndrome. ( 14373655 )
1955

Variations for Caplan's Syndrome

Expression for Caplan's Syndrome

Search GEO for disease gene expression data for Caplan's Syndrome.

GO Terms for Caplan's Syndrome

Cellular components related to Caplan's Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell surface GO:0009986 8.8 FAS HLA-A TNFRSF10A

Biological processes related to Caplan's Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 activation of cysteine-type endopeptidase activity involved in apoptotic process GO:0006919 9.32 FAS TNFRSF10A
2 cellular response to mechanical stimulus GO:0071260 9.26 FAS TNFRSF10A
3 extrinsic apoptotic signaling pathway GO:0097191 9.16 FAS TNFRSF10A
4 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902042 8.96 FAS TNFRSF10A
5 regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902041 8.62 FAS TNFRSF10A

Sources for Caplan's Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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