MCID: CRB200
MIFTS: 20

Carbapenem Allergy

Categories: Immune diseases

Aliases & Classifications for Carbapenem Allergy

MalaCards integrated aliases for Carbapenem Allergy:

Name: Carbapenem Allergy 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0040032
SNOMED-CT 67 294531005
UMLS 71 C0571443

Summaries for Carbapenem Allergy

Disease Ontology : 12 A drug allergy that has allergic trigger carbapenems.

MalaCards based summary : Carbapenem Allergy is related to cephalosporin allergy and chlorhexidine allergy. An important gene associated with Carbapenem Allergy is PPL (Periplakin), and among its related pathways/superpathways are NF-kappaB Signaling and Kit receptor signaling pathway. Related phenotypes are immune system and respiratory system

Related Diseases for Carbapenem Allergy

Diseases related to Carbapenem Allergy via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 44)
# Related Disease Score Top Affiliating Genes
1 cephalosporin allergy 10.3 PPL ENPP3
2 chlorhexidine allergy 10.3 POLB ENPP3
3 benign fibrous mesothelioma 10.2 STAT6 ALK
4 cefuroxime allergy 10.2 PPL IL13
5 cardiomyopathy, familial hypertrophic, 20 10.1 PPL IL13
6 egg allergy 10.1 IL13 ENPP3
7 breast implant-associated anaplastic large cell lymphoma 10.1 IL13 ALK
8 legume allergy 10.1 IL13 ENPP3
9 fruit allergy 10.1 IL13 ENPP3
10 pollen allergy 10.1 IL13 ENPP3
11 low-grade astrocytoma 10.0 STAT6 IL13
12 beta-lactam allergy 10.0 STAT6 IL13
13 penicillin allergy 10.0 STAT6 IL13
14 urinary schistosomiasis 10.0 STAT6 IL13
15 ige responsiveness, atopic 9.9 STAT6 IL13
16 esophagitis, eosinophilic, 1 9.9 STAT6 IL13
17 breast lipoma 9.9 GZMB ALK
18 primary cutaneous anaplastic large cell lymphoma 9.9 GZMB ALK
19 actinic prurigo 9.9 IL13 CD69
20 primary mediastinal b-cell lymphoma 9.9 SYK STAT6
21 lymphomatoid papulosis 9.9 GZMB ALK
22 t-cell lymphoma, subcutaneous panniculitis-like 9.9 GZMB ALK
23 nasal cavity disease 9.9 STAT6 IL13
24 nut allergy 9.8 STAT6 IL13 ENPP3
25 severe combined immunodeficiency, x-linked 9.8 STAT6 IL13
26 opportunistic mycosis 9.8 SYK IL13
27 food allergy 9.8 STAT6 IL13 ENPP3
28 eosinophilic pneumonia 9.8 IL13 CD69
29 reticulosarcoma 9.8 GZMB ALK
30 fungal infectious disease 9.7 SYK IL13
31 erythema multiforme 9.7 IL13 GZMB
32 respiratory allergy 9.7 STAT6 IL13
33 milk allergy 9.6 STAT6 IL13 CD69
34 allergic asthma 9.6 STAT6 IL13 CD69
35 bronchiolitis obliterans 9.6 PPL IL13 GZMB
36 parasitic helminthiasis infectious disease 9.5 STAT6 IL13
37 peripheral t-cell lymphoma 9.5 SYK GZMB ALK
38 angioimmunoblastic t-cell lymphoma 9.5 SYK GZMB
39 leishmaniasis 9.2 IL13 GZMB CD69
40 dermatitis, atopic 9.2 SYK STAT6 IL13 CD69
41 lymphoma, hodgkin, classic 9.2 STAT6 IL13 GZMB ALK
42 allergic hypersensitivity disease 8.9 SYK IL13 GZMB CD69
43 asthma 8.5 SYK STAT6 IL13 GZMB CD69
44 co-trimoxazole allergy 8.5 SYK STAT6 PPL GZMB ENPP3 CD69

Graphical network of the top 20 diseases related to Carbapenem Allergy:



Diseases related to Carbapenem Allergy

Symptoms & Phenotypes for Carbapenem Allergy

MGI Mouse Phenotypes related to Carbapenem Allergy:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 immune system MP:0005387 9.7 CD69 ENPP3 IL13 POLB PPL STAT6
2 respiratory system MP:0005388 9.43 ALK ENPP3 IL13 POLB STAT6 SYK
3 skeleton MP:0005390 9.1 ALK CD69 IL13 KLK4 POLB SYK

Drugs & Therapeutics for Carbapenem Allergy

Search Clinical Trials , NIH Clinical Center for Carbapenem Allergy

Genetic Tests for Carbapenem Allergy

Anatomical Context for Carbapenem Allergy

Publications for Carbapenem Allergy

Articles related to Carbapenem Allergy:

# Title Authors PMID Year
1
Overview and Insights into Carbapenem Allergy. 61
31398843 2019
2
Allergic cross-sensitivity between penicillin, carbapenem, and monobactam antibiotics: what are the chances? 61
19193579 2009
3
Successful meropenem desensitization in a patient with cystic fibrosis. 61
14519038 2003

Variations for Carbapenem Allergy

Expression for Carbapenem Allergy

Search GEO for disease gene expression data for Carbapenem Allergy.

Pathways for Carbapenem Allergy

Pathways related to Carbapenem Allergy according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.44 SYK STAT6 GZMB ENPP3
2
Show member pathways
11.34 SYK ENPP3 CD69
3 10.82 STAT6 IL13

GO Terms for Carbapenem Allergy

Cellular components related to Carbapenem Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein-containing complex GO:0032991 8.92 SYK POLB CD69 ALK

Biological processes related to Carbapenem Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of cell proliferation GO:0042127 9.33 SYK STAT6 ALK
2 positive regulation of type I interferon production GO:0032481 9.26 SYK STAT6
3 positive regulation of mast cell degranulation GO:0043306 8.96 SYK IL13
4 positive regulation of cold-induced thermogenesis GO:0120162 8.8 SYK STAT6 IL13

Sources for Carbapenem Allergy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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