MCID: CRB200
MIFTS: 21

Carbapenem Allergy

Categories: Immune diseases

Aliases & Classifications for Carbapenem Allergy

MalaCards integrated aliases for Carbapenem Allergy:

Name: Carbapenem Allergy 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0040032
UMLS 71 C0571443

Summaries for Carbapenem Allergy

MalaCards based summary : Carbapenem Allergy is related to cephalosporin allergy and cefuroxime allergy. An important gene associated with Carbapenem Allergy is PPL (Periplakin), and among its related pathways/superpathways are NF-kappaB Signaling and Kit receptor signaling pathway. Affiliated tissues include t cells, breast and b cells, and related phenotypes are immune system and respiratory system

Related Diseases for Carbapenem Allergy

Diseases related to Carbapenem Allergy via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 35)
# Related Disease Score Top Affiliating Genes
1 cephalosporin allergy 10.3 PPL ENPP3
2 cefuroxime allergy 10.1 PPL IL13
3 cardiomyopathy, familial hypertrophic, 20 10.1 PPL IL13
4 pollen allergy 10.0 IL13 ENPP3
5 low-grade astrocytoma 9.9 STAT6 IL13
6 penicillin allergy 9.9 STAT6 IL13
7 urinary schistosomiasis 9.9 STAT6 IL13
8 breast lipoma 9.9 GZMB ALK
9 primary cutaneous anaplastic large cell lymphoma 9.9 GZMB ALK
10 actinic prurigo 9.9 IL13 CD69
11 esophagitis, eosinophilic, 1 9.9 STAT6 IL13
12 ige responsiveness, atopic 9.9 STAT6 IL13
13 primary mediastinal b-cell lymphoma 9.9 SYK STAT6
14 lymphomatoid papulosis 9.9 GZMB ALK
15 t-cell lymphoma, subcutaneous panniculitis-like 9.8 GZMB ALK
16 nasal cavity disease 9.8 STAT6 IL13
17 beta-lactam allergy 9.8 STAT6 IL13 ENPP3
18 nut allergy 9.8 STAT6 IL13 ENPP3
19 reticulosarcoma 9.8 GZMB ALK
20 eosinophilic pneumonia 9.8 IL13 CD69
21 food allergy 9.7 STAT6 IL13 ENPP3
22 severe combined immunodeficiency, x-linked 9.7 STAT6 IL13
23 respiratory allergy 9.6 STAT6 IL13
24 angioimmunoblastic t-cell lymphoma 9.6 SYK GZMB
25 bronchiolitis obliterans 9.5 PPL IL13 GZMB
26 peripheral t-cell lymphoma 9.5 SYK GZMB ALK
27 milk allergy 9.5 STAT6 IL13 CD69
28 allergic asthma 9.5 STAT6 IL13 CD69
29 parasitic helminthiasis infectious disease 9.5 STAT6 IL13
30 leishmaniasis 9.2 IL13 GZMB CD69
31 lymphoma, hodgkin, classic 9.1 STAT6 IL13 GZMB ALK
32 allergic hypersensitivity disease 8.9 SYK STAT6 IL13 ENPP3 CD69
33 dermatitis, atopic 8.9 SYK STAT6 IL13 ENPP3 CD69
34 asthma 8.5 SYK STAT6 IL13 GZMB CD69
35 co-trimoxazole allergy 7.8 SYK STAT6 PPL IL13 GZMB ENPP3

Graphical network of the top 20 diseases related to Carbapenem Allergy:



Diseases related to Carbapenem Allergy

Symptoms & Phenotypes for Carbapenem Allergy

MGI Mouse Phenotypes related to Carbapenem Allergy:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 immune system MP:0005387 9.7 CD69 ENPP3 IL13 POLB PPL STAT6
2 respiratory system MP:0005388 9.43 ALK ENPP3 IL13 POLB STAT6 SYK
3 skeleton MP:0005390 9.1 ALK CD69 IL13 KLK4 POLB SYK

Drugs & Therapeutics for Carbapenem Allergy

Search Clinical Trials , NIH Clinical Center for Carbapenem Allergy

Genetic Tests for Carbapenem Allergy

Anatomical Context for Carbapenem Allergy

MalaCards organs/tissues related to Carbapenem Allergy:

40
T Cells, Breast, B Cells

Publications for Carbapenem Allergy

Articles related to Carbapenem Allergy:

# Title Authors PMID Year
1
Overview and Insights into Carbapenem Allergy. 61
31398843 2019
2
Allergic cross-sensitivity between penicillin, carbapenem, and monobactam antibiotics: what are the chances? 61
19193579 2009
3
Successful meropenem desensitization in a patient with cystic fibrosis. 61
14519038 2003

Variations for Carbapenem Allergy

Expression for Carbapenem Allergy

Search GEO for disease gene expression data for Carbapenem Allergy.

Pathways for Carbapenem Allergy

Pathways related to Carbapenem Allergy according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.44 SYK STAT6 GZMB ENPP3
2
Show member pathways
11.34 SYK ENPP3 CD69
3 10.82 STAT6 IL13

GO Terms for Carbapenem Allergy

Cellular components related to Carbapenem Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein-containing complex GO:0032991 8.92 SYK POLB CD69 ALK

Biological processes related to Carbapenem Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of type I interferon production GO:0032481 9.16 SYK STAT6
2 positive regulation of mast cell degranulation GO:0043306 8.96 SYK IL13
3 positive regulation of cold-induced thermogenesis GO:0120162 8.8 SYK STAT6 IL13

Sources for Carbapenem Allergy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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