MCID: CRB200
MIFTS: 20

Carbapenem Allergy

Categories: Immune diseases

Aliases & Classifications for Carbapenem Allergy

MalaCards integrated aliases for Carbapenem Allergy:

Name: Carbapenem Allergy 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0040032
SNOMED-CT 67 294531005
UMLS 71 C0571443

Summaries for Carbapenem Allergy

Disease Ontology : 12 A drug allergy that has allergic trigger carbapenems.

MalaCards based summary : Carbapenem Allergy is related to egg allergy and legume allergy. An important gene associated with Carbapenem Allergy is ENPP3 (Ectonucleotide Pyrophosphatase/Phosphodiesterase 3), and among its related pathways/superpathways are Akt Signaling and NF-kappaB Signaling. Related phenotype is respiratory system.

Related Diseases for Carbapenem Allergy

Diseases related to Carbapenem Allergy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 54)
# Related Disease Score Top Affiliating Genes
1 egg allergy 10.1 IL13 ENPP3
2 legume allergy 10.1 IL13 ENPP3
3 fruit allergy 10.1 IL13 ENPP3
4 drug allergy 10.1 IL13 ENPP3
5 pollen allergy 10.1 IL13 ENPP3
6 low-grade astrocytoma 10.1 STAT6 IL13
7 primary mediastinal b-cell lymphoma 10.1 SYK STAT6
8 respiratory allergy 10.1 IL13 ENPP3
9 penicillin allergy 10.1 STAT6 IL13
10 urinary schistosomiasis 10.1 STAT6 IL13
11 schistosomiasis 10.1 STAT6 IL13
12 esophagitis, eosinophilic, 1 10.1 STAT6 IL13
13 esophagitis 10.1 STAT6 IL13
14 actinic prurigo 10.0 IL13 CD69
15 chronic urticaria 10.0 IL13 ENPP3
16 urticaria 10.0 IL13 ENPP3
17 severe combined immunodeficiency, x-linked 10.0 STAT6 IL13
18 parasitic helminthiasis infectious disease 10.0 STAT6 IL13
19 opportunistic mycosis 10.0 SYK IL13
20 fungal infectious disease 10.0 SYK IL13
21 hantavirus pulmonary syndrome 10.0 SYK GZMB
22 eosinophilic pneumonia 10.0 IL13 CD69
23 angioimmunoblastic t-cell lymphoma 9.9 SYK GZMB
24 mastocytosis 9.9 IL13 ENPP3
25 benign fibrous mesothelioma 9.9 STAT6 ALK
26 nut allergy 9.9 STAT6 IL13 ENPP3
27 beta-lactam allergy 9.9 STAT6 IL13 ENPP3
28 food allergy 9.9 STAT6 IL13 ENPP3
29 chronic fatigue syndrome 9.9 IL13 CD69
30 bronchiolitis obliterans 9.9 IL13 GZMB
31 breast implant-associated anaplastic large cell lymphoma 9.9 IL13 ALK
32 cutaneous leishmaniasis 9.9 IL13 GZMB
33 bronchial disease 9.9 STAT6 IL13
34 breast lipoma 9.8 GZMB ALK
35 milk allergy 9.8 STAT6 IL13 CD69
36 primary cutaneous anaplastic large cell lymphoma 9.8 GZMB ALK
37 lymphomatoid papulosis 9.8 GZMB ALK
38 allergic asthma 9.8 STAT6 IL13 CD69
39 t-cell lymphoma, subcutaneous panniculitis-like 9.8 GZMB ALK
40 phenytoin allergy 9.8 SYK STAT6 GZMB
41 reticulosarcoma 9.8 GZMB ALK
42 primary bacterial infectious disease 9.7 IL13 CD69
43 mature t-cell and nk-cell lymphoma 9.7 GZMB ALK
44 immune deficiency disease 9.6 SYK IL13 CD69
45 b-cell lymphoma 9.6 SYK STAT6 ALK
46 autoimmune disease 9.6 SYK IL13 CD69
47 alopecia areata 9.6 IL13 GZMB
48 dermatitis, atopic 9.6 SYK STAT6 IL13 CD69
49 peripheral t-cell lymphoma 9.6 SYK GZMB ALK
50 asthma 9.6 SYK STAT6 IL13 CD69

Graphical network of the top 20 diseases related to Carbapenem Allergy:



Diseases related to Carbapenem Allergy

Symptoms & Phenotypes for Carbapenem Allergy

MGI Mouse Phenotypes related to Carbapenem Allergy:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 respiratory system MP:0005388 9.02 ALK ENPP3 IL13 STAT6 SYK

Drugs & Therapeutics for Carbapenem Allergy

Search Clinical Trials , NIH Clinical Center for Carbapenem Allergy

Genetic Tests for Carbapenem Allergy

Anatomical Context for Carbapenem Allergy

Publications for Carbapenem Allergy

Articles related to Carbapenem Allergy:

# Title Authors PMID Year
1
Overview and Insights into Carbapenem Allergy. 61
31398843 2019
2
Allergic cross-sensitivity between penicillin, carbapenem, and monobactam antibiotics: what are the chances? 61
19193579 2009
3
Successful meropenem desensitization in a patient with cystic fibrosis. 61
14519038 2003

Variations for Carbapenem Allergy

Expression for Carbapenem Allergy

Search GEO for disease gene expression data for Carbapenem Allergy.

Pathways for Carbapenem Allergy

Pathways related to Carbapenem Allergy according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.77 SYK STAT6 IL13 ALK
2 11.44 SYK STAT6 GZMB ENPP3
3
Show member pathways
11.34 SYK ENPP3 CD69
4 11.16 IL13 GZMB
5 10.82 STAT6 IL13

GO Terms for Carbapenem Allergy

Cellular components related to Carbapenem Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 external side of plasma membrane GO:0009897 8.8 IL13 ENPP3 CD69

Biological processes related to Carbapenem Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of cell proliferation GO:0042127 9.33 SYK STAT6 ALK
2 positive regulation of type I interferon production GO:0032481 9.32 SYK STAT6
3 positive regulation of interleukin-10 production GO:0032733 9.26 SYK IL13
4 positive regulation of mast cell degranulation GO:0043306 8.96 SYK IL13
5 positive regulation of cold-induced thermogenesis GO:0120162 8.8 SYK STAT6 IL13

Sources for Carbapenem Allergy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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