MCID: CRB134
MIFTS: 15

Carbon Monoxide-Induced Parkinsonism

Categories: Neuronal diseases, Rare diseases

Aliases & Classifications for Carbon Monoxide-Induced Parkinsonism

MalaCards integrated aliases for Carbon Monoxide-Induced Parkinsonism:

Name: Carbon Monoxide-Induced Parkinsonism 59
Co-Induced Parkinsonism 59

Classifications:

Orphanet: 59  
Rare neurological diseases


External Ids:

Orphanet 59 ORPHA306686
UMLS via Orphanet 74 C0393565
ICD10 via Orphanet 34 G21.2

Summaries for Carbon Monoxide-Induced Parkinsonism

MalaCards based summary : Carbon Monoxide-Induced Parkinsonism, also known as co-induced parkinsonism, is related to depression and primary progressive freezing gait. The drugs Carbon monoxide and Tetrabenazine have been mentioned in the context of this disorder. Affiliated tissues include brain, and related phenotypes are behavioral abnormality and memory impairment

Related Diseases for Carbon Monoxide-Induced Parkinsonism

Diseases related to Carbon Monoxide-Induced Parkinsonism via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 depression 10.1
2 primary progressive freezing gait 9.8

Symptoms & Phenotypes for Carbon Monoxide-Induced Parkinsonism

Human phenotypes related to Carbon Monoxide-Induced Parkinsonism:

59 32 (show all 9)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 behavioral abnormality 59 32 hallmark (90%) Very frequent (99-80%) HP:0000708
2 memory impairment 59 32 hallmark (90%) Very frequent (99-80%) HP:0002354
3 rigidity 59 32 frequent (33%) Frequent (79-30%) HP:0002063
4 abnormality of the upper limb 59 32 frequent (33%) Frequent (79-30%) HP:0002817
5 bradykinesia 59 32 frequent (33%) Frequent (79-30%) HP:0002067
6 abnormality of the periventricular white matter 59 32 hallmark (90%) Very frequent (99-80%) HP:0002518
7 decreased facial expression 59 32 frequent (33%) Frequent (79-30%) HP:0004673
8 elevated brain choline level by mrs 59 32 hallmark (90%) Very frequent (99-80%) HP:0012706
9 reduced brain n-acetyl aspartate level by mrs 59 32 hallmark (90%) Very frequent (99-80%) HP:0012708

Drugs & Therapeutics for Carbon Monoxide-Induced Parkinsonism

Drugs for Carbon Monoxide-Induced Parkinsonism (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 6)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Carbon monoxide Approved, Investigational Phase 3 630-08-0 281
2
Tetrabenazine Approved, Investigational Phase 3 58-46-8 6018
3 Neurotransmitter Uptake Inhibitors Phase 3
4 Adrenergic Agents Phase 3
5 Neurotransmitter Agents Phase 3
6 Antimetabolites Phase 3

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Targeting Monoaminergic Neuronal Networks in the Parkinsonian Patients After Carbon Monoxide Intoxication Unknown status NCT02138864 Phase 3

Search NIH Clinical Center for Carbon Monoxide-Induced Parkinsonism

Genetic Tests for Carbon Monoxide-Induced Parkinsonism

Anatomical Context for Carbon Monoxide-Induced Parkinsonism

MalaCards organs/tissues related to Carbon Monoxide-Induced Parkinsonism:

41
Brain

Publications for Carbon Monoxide-Induced Parkinsonism

Articles related to Carbon Monoxide-Induced Parkinsonism:

# Title Authors Year
1
Major depression and carbon monoxide-induced parkinsonism: diagnosis, computerized axial tomography, and response to L-dopa. ( 4020369 )
1985
2
Carbon monoxide-induced Parkinsonism. ( 5038884 )
1972

Variations for Carbon Monoxide-Induced Parkinsonism

Expression for Carbon Monoxide-Induced Parkinsonism

Search GEO for disease gene expression data for Carbon Monoxide-Induced Parkinsonism.

Pathways for Carbon Monoxide-Induced Parkinsonism

GO Terms for Carbon Monoxide-Induced Parkinsonism

Sources for Carbon Monoxide-Induced Parkinsonism

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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