MCID: CRB134
MIFTS: 18

Carbon Monoxide-Induced Parkinsonism

Categories: Neuronal diseases, Rare diseases

Aliases & Classifications for Carbon Monoxide-Induced Parkinsonism

MalaCards integrated aliases for Carbon Monoxide-Induced Parkinsonism:

Name: Carbon Monoxide-Induced Parkinsonism 60
Co-Induced Parkinsonism 60

Classifications:

Orphanet: 60  
Rare neurological diseases


External Ids:

ICD10 via Orphanet 35 G21.2
UMLS via Orphanet 75 C0393565
Orphanet 60 ORPHA306686

Summaries for Carbon Monoxide-Induced Parkinsonism

MalaCards based summary : Carbon Monoxide-Induced Parkinsonism, also known as co-induced parkinsonism, is related to depression and primary progressive freezing gait. The drugs Carbon monoxide and Tetrabenazine have been mentioned in the context of this disorder. Affiliated tissues include brain, and related phenotypes are behavioral abnormality and memory impairment

Related Diseases for Carbon Monoxide-Induced Parkinsonism

Diseases related to Carbon Monoxide-Induced Parkinsonism via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 depression 10.1
2 primary progressive freezing gait 9.9

Symptoms & Phenotypes for Carbon Monoxide-Induced Parkinsonism

Human phenotypes related to Carbon Monoxide-Induced Parkinsonism:

60 33 (show all 9)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 behavioral abnormality 60 33 hallmark (90%) Very frequent (99-80%) HP:0000708
2 memory impairment 60 33 hallmark (90%) Very frequent (99-80%) HP:0002354
3 abnormality of the periventricular white matter 60 33 hallmark (90%) Very frequent (99-80%) HP:0002518
4 elevated brain choline level by mrs 60 33 hallmark (90%) Very frequent (99-80%) HP:0012706
5 reduced brain n-acetyl aspartate level by mrs 60 33 hallmark (90%) Very frequent (99-80%) HP:0012708
6 rigidity 60 33 frequent (33%) Frequent (79-30%) HP:0002063
7 abnormality of the upper limb 60 33 frequent (33%) Frequent (79-30%) HP:0002817
8 bradykinesia 60 33 frequent (33%) Frequent (79-30%) HP:0002067
9 decreased facial expression 60 33 frequent (33%) Frequent (79-30%) HP:0004673

Drugs & Therapeutics for Carbon Monoxide-Induced Parkinsonism

Drugs for Carbon Monoxide-Induced Parkinsonism (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 6)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Carbon monoxide Approved, Investigational Phase 3 630-08-0 281
2
Tetrabenazine Approved, Investigational Phase 3 58-46-8 6018
3 Neurotransmitter Uptake Inhibitors Phase 3
4 Antimetabolites Phase 3
5 Neurotransmitter Agents Phase 3
6 Adrenergic Agents Phase 3

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Targeting Monoaminergic Neuronal Networks in the Parkinsonian Patients After Carbon Monoxide Intoxication Unknown status NCT02138864 Phase 3

Search NIH Clinical Center for Carbon Monoxide-Induced Parkinsonism

Genetic Tests for Carbon Monoxide-Induced Parkinsonism

Anatomical Context for Carbon Monoxide-Induced Parkinsonism

MalaCards organs/tissues related to Carbon Monoxide-Induced Parkinsonism:

42
Brain

Publications for Carbon Monoxide-Induced Parkinsonism

Articles related to Carbon Monoxide-Induced Parkinsonism:

# Title Authors Year
1
Primary progressive freezing gait in a patient with CO-induced parkinsonism. ( 20629158 )
2010
2
Major depression and carbon monoxide-induced parkinsonism: diagnosis, computerized axial tomography, and response to L-dopa. ( 4020369 )
1985
3
Carbon monoxide-induced Parkinsonism. ( 5038884 )
1972

Variations for Carbon Monoxide-Induced Parkinsonism

Expression for Carbon Monoxide-Induced Parkinsonism

Search GEO for disease gene expression data for Carbon Monoxide-Induced Parkinsonism.

Pathways for Carbon Monoxide-Induced Parkinsonism

GO Terms for Carbon Monoxide-Induced Parkinsonism

Sources for Carbon Monoxide-Induced Parkinsonism

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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