MCID: CRD001
MIFTS: 44

Cardiac Tamponade

Categories: Cardiovascular diseases

Aliases & Classifications for Cardiac Tamponade

MalaCards integrated aliases for Cardiac Tamponade:

Name: Cardiac Tamponade 12 73 54 44 15 17 70
Pericardial Tamponade 12
Rose's Tamponade 12

Classifications:



External Ids:

Disease Ontology 12 DOID:115
ICD9CM 34 423.3
MeSH 44 D002305
NCIt 50 C50481
SNOMED-CT 67 266295005
ICD10 32 I31.4
UMLS 70 C0007177

Summaries for Cardiac Tamponade

Disease Ontology : 12 A pericardial effusion in which fluid accumulates in the pericardium (the sac in which the heart is enclosed) and the pericardial spaces fills up faster than the pericardial sac can stretch.

MalaCards based summary : Cardiac Tamponade, also known as pericardial tamponade, is related to pericardial tuberculosis and hemopericardium. An important gene associated with Cardiac Tamponade is F8 (Coagulation Factor VIII), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Collagen chain trimerization. Affiliated tissues include heart, kidney and lung, and related phenotypes are cardiovascular system and homeostasis/metabolism

Wikipedia : 73 Cardiac tamponade, also known as pericardial tamponade, is when fluid in the pericardium (the sac around... more...

Related Diseases for Cardiac Tamponade

Diseases related to Cardiac Tamponade via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 925)
# Related Disease Score Top Affiliating Genes
1 pericardial tuberculosis 32.0 CRP ADA
2 hemopericardium 31.6 TNNI3 PLG F9 F3 F2 CRP
3 cardiogenic shock 31.3 PLAT NPPB
4 infective endocarditis 30.9 TNNI3 F2 CRP
5 pericarditis 30.9 TNNI3 TNFRSF1A NPPB CRP ALB ADA
6 cardiac rupture 30.8 PLAT CRP
7 hemopneumothorax 30.6 F3 F2
8 kawasaki disease 30.6 NPPB CRP ALB
9 juvenile rheumatoid arthritis 30.5 TNFRSF1A CRP ALB
10 rheumatic fever 30.5 NPPB ALB ACE
11 myocarditis 30.5 TNNI3 PIK3C2A NPPB ACE
12 volvulus of midgut 30.4 TNNI3 CRP ALB
13 uremia 30.4 REN CRP ALB ACE
14 mediastinitis 30.4 F3 F2 CRP ALB
15 acalculous cholecystitis 30.3 F2 CRP ALB
16 hemophilia 30.3 F9 F8 F7
17 coronary aneurysm 30.3 PLG CRP ALB
18 lemierre's syndrome 30.3 F3 F2 CRP
19 dengue hemorrhagic fever 30.3 F3 F2 ALB
20 chickenpox 30.3 CRP ALB ADA
21 acute myocarditis 30.3 TNNI3 NPPB CRP ACE
22 meningitis 30.3 CRP ALB ADA
23 atrial fibrillation 30.2 PLAT NPPB F9 F2 CRP ACE
24 hepatic coma 30.2 F3 F2 ALB
25 esophageal varix 30.2 F3 F2 ALB
26 kidney disease 30.2 REN NPPB F3 CRP ALB ACE
27 malignant hypertension 30.2 REN NPPB ACE
28 urinary tract infection 30.1 CRP ACE
29 acquired immunodeficiency syndrome 30.1 TNFRSF1A F9 CRP ALB ADA
30 amyloidosis 30.1 TNNI3 TNFRSF1A NPPB CRP ALB
31 covid-19 30.1 TNNI3 NPPB F3 ACE
32 hypothyroidism 30.1 REN PIK3C2A F8 CRP ALB ACE
33 cardiac tuberculosis 30.1 NPPB CRP ACE
34 atrioventricular block 30.1 TNNI3 PIK3C2A NPPB ACE
35 proteinuria, chronic benign 30.0 REN ALB ACE
36 end stage renal disease 30.0 REN NPPB CRP ALB ACE
37 acute kidney failure 30.0 REN PIK3C2A F2 ALB
38 constrictive pericarditis 30.0 TNNI3 REN NPPB CRP ALB ADA
39 purpura 30.0 F3 F2 CRP ACE
40 mycoplasma pneumoniae pneumonia 30.0 F3 CRP ACE
41 hemophilia a 29.9 F9 F8 F7 F3
42 hypertensive heart disease 29.9 REN NPPB ACE
43 hepatitis a 29.9 F3 F2 ALB
44 cardiac arrest 29.9 TNNI3 REN PIK3C2A NPPB ALB ACE
45 thrombophilia due to thrombin defect 29.9 PLAT F8 F3 F2
46 cholangitis 29.8 F3 F2 CRP ALB
47 pleural empyema 29.8 PLG F2 CRP ALB ADA
48 lung abscess 29.8 CRP ALB
49 peritonitis 29.8 F2 CRP ALB ADA
50 pneumonia 29.8 PIK3C2A CRP ALB ACE

Graphical network of the top 20 diseases related to Cardiac Tamponade:



Diseases related to Cardiac Tamponade

Symptoms & Phenotypes for Cardiac Tamponade

MGI Mouse Phenotypes related to Cardiac Tamponade:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.35 ACE ADA ALB CRP F2 F3
2 homeostasis/metabolism MP:0005376 10.31 ACE ADA ALB CRP F2 F3
3 immune system MP:0005387 10.22 ACE ADA ALB CRP F2 F3
4 hematopoietic system MP:0005397 10.2 ACE ADA F3 F8 F9 GATA2
5 mortality/aging MP:0010768 10.2 ACE ADA ALB F2 F3 F7
6 liver/biliary system MP:0005370 9.91 ACE ADA ALB F9 GATA2 PLG
7 muscle MP:0005369 9.86 ADA ALB F2 F3 PLAT REN
8 renal/urinary system MP:0005367 9.76 ACE ADA ALB GATA2 PIK3C2A PLG
9 reproductive system MP:0005389 9.61 ACE ADA F2 F8 GATA2 PLAT
10 respiratory system MP:0005388 9.17 ADA F2 F3 PLAT PLG TNFRSF1A

Drugs & Therapeutics for Cardiac Tamponade

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Atrial Fibrillation and Pericardial Drainage: Incidence of Postoperative Atrial Fibrillation According to the Type of Mediastinal Drainage Catheters Unknown status NCT02808897 Phase 4
2 Drainage or Pericardiocentesis Alone for Recurrent Non-malignant Pericardial Effusions Requiring Intervention. Unknown status NCT01665495
3 Evaluation of Different Strategies of Pericardial Drainage After Aortic Valvular Surgery: A Prospective Randomized Trial Completed NCT00684125
4 Validation of Epworth Richmond's Echocardiography Education Focused Year Completed NCT02961439

Search NIH Clinical Center for Cardiac Tamponade

Cochrane evidence based reviews: cardiac tamponade

Genetic Tests for Cardiac Tamponade

Anatomical Context for Cardiac Tamponade

MalaCards organs/tissues related to Cardiac Tamponade:

40
Heart, Kidney, Lung, Thyroid, Myeloid, Liver, Bone Marrow

Publications for Cardiac Tamponade

Articles related to Cardiac Tamponade:

(show top 50) (show all 6281)
# Title Authors PMID Year
1
Cardiac tamponade in a patient with moderate hemophilia A and factor VIII Inhibitors. 61 54
16450022 2006
2
Pericardial effusion in anti-complement factor H antibody-associated atypical hemolytic uremic syndrome: two case reports. 61
33386505 2021
3
Meta-Analysis Comparing the Safety and Efficacy of Single vs Dual Antiplatelet Therapy in Post Transcatheter Aortic Valve Implantation Patients. 61
33454348 2021
4
European Resuscitation Council Guidelines 2021: Cardiac arrest in special circumstances. 61
33773826 2021
5
Surgical outcomes of acute type A aortic dissection in patients undergoing cardiopulmonary resuscitation. 61
32008759 2021
6
Late Cardiac Tamponade 4 Years After Total Artificial Heart Implantation. 61
32987020 2021
7
Hickman catheter-induced cardiac tamponade-related cardiac perforation management by mediastinotomy in children and a review of the literature. 61
33665325 2021
8
Usefulness of HVAD Waveforms as Diagnostic Assistance for Cardiac Tamponade. 61
33181545 2021
9
Pericardial-Peritoneal Window as an Alternative Treatment for Large and Recurrent Pericardial Effusion Post-Pericardiotomy. 61
33656833 2021
10
Pericardial effusion uncovering underlying hypothyroidism. 61
33768953 2021
11
Cardiac tamponade secondary to leptospirosis. A rare association: A case report. 61
33717381 2021
12
Pericardial metastasis of parotid mucoepidermoid carcinoma diagnosed by pericardial biopsy. 61
33750609 2021
13
Graves' disease inducing a massive cardiac tamponade. 61
33685911 2021
14
Accidental Cannulation of the Cardiac Venous System During Pericardiocentesis. 61
33646967 2021
15
Clinical significance of incidentally detected lead perforations by computed tomography. 61
33786829 2021
16
Long-term IV access in paediatrics - why, what, where, who and how. 61
33147351 2021
17
Atrio-aortic erosion caused by Amplatzer Atrial Septal Occluder - a case report. 61
33743762 2021
18
Cancer related emergencies with the chief complaint of pain: Incidence, ED recognition, and quality of care. 61
33706045 2021
19
Major adverse clinical events associated with implantation of a leadless intracardiac pacemaker. 61
33713856 2021
20
Active clearance vs conventional management of chest tubes after cardiac surgery: a randomized controlled study. 61
33757537 2021
21
Off-pump external pericardial patch repair for post-infarct left ventricular free wall rupture: a case series. 61
33758654 2021
22
Left ventricular pseudoaneurysm: An unexpected finding. 61
33384752 2021
23
Isolated Right Atrial Rupture From Blunt Chest Trauma in Motor Vehicle Collisions: Mechanisms of Injury and Outcomes. 61
32649316 2021
24
Outcomes with Orbital and Rotational Atherectomy for Inpatient Percutaneous Coronary Intervention. 61
33710602 2021
25
Transvenous lead extraction in 1,000 patients guided by intraprocedural risk stratification without surgical backup. 61
33781982 2021
26
Left atrial appendage closure device complicated by late-onset pericardial effusion and tamponade: a case report. 61
33693307 2021
27
Sex Differences of Clinical Presentation and Outcomes in Propensity-Matched Patients with Acute Type A Aortic Dissection. 61
33798045 2021
28
[Effectiveness and safety of idarucizumab in the management of perioperative complications of atrial fibrillation catheter ablation in atrial fibrillation patients under dabigatran therapy]. 61
33706454 2021
29
Ozaki procedure complicated by postpericardiotomy syndrome and cardiac tamponade. 61
32945199 2021
30
Cardiac Tamponade during Tocilizumab Therapy in a Patient with Rheumatoid Arthritis and Anti-DNA Antibody Positivity. 61
33776015 2021
31
Calcified constrictive pericarditis resulting in tamponade in a patient with systemic lupus erythematosus. 61
33206224 2021
32
Needle in the heart: a rare case of cardiac tamponade caused by a migrated foreign body and mimicking ST segment elevation myocardial infarction. 61
33730997 2021
33
Clinical profile, treatment and outcome of Kawasaki disease: A single-center experience from a tertiary care referral center of Assam, north-east India. 61
33523594 2021
34
Cardiac tamponade due to advanced gastric cancer: case report and review. 61
33631647 2021
35
[A clinical analysis of pericardial effusion caused by central venous catheterization in preterm infants]. 61
33691919 2021
36
Cardiac tamponade following aortic root erosion by an Amplatzer PFO-Occluder in a 41-year-old woman: Only a matter of sizing? 61
33717377 2021
37
Cardiac Tamponade Due to Very Late Perforation of Left Atrium by Atrial Septal Defect Occluder. 61
33582082 2021
38
Activated Prothrombin Complex Concentrate for coagulopathy reversal secondary to ischemic hepatic injury due to cardiac tamponade: A case report. 61
33714001 2021
39
Subepicardial aneurysm with free wall rupture and its successful surgical intervention: a case report. 61
33738421 2021
40
A successfully treated case of primary purulent pericarditis complicated by cardiac tamponade and pneumopericardium. 61
33040519 2021
41
Transseptal Puncture Learning Curve for Transcatheter Edge-to-Edge Mitral Valve Repair. 61
33570438 2021
42
Chylopericardium Effusion in a Lac Alaotra Bamboo Lemur (Hapalemur alaotrensis). 61
33669516 2021
43
Signs of early cardiac tamponade induced by Minoxidil. 61
32778436 2021
44
Percutaneous pericardiocentesis for pericardial effusion: predictors of mortality and outcomes. 61
33616878 2021
45
The role of point-of-care ultrasound in the diagnosis of pericardial effusion: a single academic center retrospective study. 61
33538920 2021
46
When Echinococcus granulosus transmigrates from the liver into the pericardium: a case report. 61
33598114 2021
47
Similar outcomes with manual contact force ablation catheters and traditional catheters in the treatment of outflow tract premature ventricular complexes. 61
33576378 2021
48
Gastropericardial fistula induced acute purulent pericarditis. 61
33608167 2021
49
Resuscitative thoracotomy. 61
33205624 2021
50
Left atrial appendage occlusion in chicken-wing anatomies: Imaging assessment, procedural, and clinical outcomes of the "sandwich technique". 61
33580751 2021

Variations for Cardiac Tamponade

Expression for Cardiac Tamponade

Search GEO for disease gene expression data for Cardiac Tamponade.

Pathways for Cardiac Tamponade

Pathways related to Cardiac Tamponade according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.99 PLG PLAT GATA2 F9 F8 F7
2
Show member pathways
12.53 F9 F8 F7 F3 F2
3
Show member pathways
11.97 PLG PLAT F7 F2 CRP ALB
4
Show member pathways
11.7 PLG PLAT F9 F8 F7 F3
5
Show member pathways
11.67 F9 F7 F2
6 11.33 PLG PLAT F9 F8 F7 F3
7 10.91 PLG PLAT ACE
8 10.67 F9 F7 F2
9 10.55 PLG PLAT

GO Terms for Cardiac Tamponade

Cellular components related to Cardiac Tamponade according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell surface GO:0009986 9.8 TNFRSF1A PLG PLAT F3 ADA
2 extracellular region GO:0005576 9.77 TNFRSF1A REN PLG PLAT NPPB F9
3 endoplasmic reticulum lumen GO:0005788 9.72 F9 F8 F7 F2 ALB
4 collagen-containing extracellular matrix GO:0062023 9.63 PLG PLAT F9 F7 F3 F2
5 Golgi lumen GO:0005796 9.61 F9 F7 F2
6 platelet alpha granule lumen GO:0031093 9.54 PLG F8 ALB
7 extracellular space GO:0005615 9.47 TNFRSF1A REN PLG PLAT NPPB F9
8 serine-type peptidase complex GO:1905286 9.26 F7 F3

Biological processes related to Cardiac Tamponade according to GeneCards Suite gene sharing:

(show all 16)
# Name GO ID Score Top Affiliating Genes
1 ER to Golgi vesicle-mediated transport GO:0006888 9.76 F9 F8 F7 F2
2 proteolysis GO:0006508 9.7 REN PLG PLAT F9 F7 F2
3 regulation of blood pressure GO:0008217 9.65 REN NPPB ACE
4 heart contraction GO:0060047 9.56 TNNI3 ACE
5 positive regulation of blood coagulation GO:0030194 9.55 F7 F2
6 amyloid-beta metabolic process GO:0050435 9.54 REN ACE
7 acute-phase response GO:0006953 9.54 F8 F2 CRP
8 positive regulation of positive chemotaxis GO:0050927 9.52 F7 F3
9 angiotensin maturation GO:0002003 9.51 REN ACE
10 fibrinolysis GO:0042730 9.5 PLG PLAT F2
11 negative regulation of fibrinolysis GO:0051918 9.49 PLG F2
12 positive regulation of platelet-derived growth factor receptor signaling pathway GO:0010641 9.43 F7 F3
13 blood coagulation, intrinsic pathway GO:0007597 9.43 F9 F8 F2
14 hemostasis GO:0007599 9.43 PLG F9 F8 F7 F3 F2
15 blood coagulation, extrinsic pathway GO:0007598 9.4 F7 F3
16 blood coagulation GO:0007596 9.23 PLG PLAT GATA2 F9 F8 F7

Molecular functions related to Cardiac Tamponade according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hydrolase activity GO:0016787 9.97 REN PLG PLAT F9 F7 F2
2 signaling receptor binding GO:0005102 9.8 REN PLG PLAT NPPB F7 F2
3 peptidase activity GO:0008233 9.7 REN PLG PLAT F9 F7 F2
4 serine-type peptidase activity GO:0008236 9.65 PLG PLAT F9 F7 F2
5 endopeptidase activity GO:0004175 9.35 REN PLG F9 F7 ACE
6 serine-type endopeptidase activity GO:0004252 9.1 PLG PLAT F9 F7 F3 F2

Sources for Cardiac Tamponade

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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