MCID: CRD001
MIFTS: 45

Cardiac Tamponade

Categories: Cardiovascular diseases
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Aliases & Classifications for Cardiac Tamponade

MalaCards integrated aliases for Cardiac Tamponade:

Name: Cardiac Tamponade 11 75 53 43 14 16 71 33
Pericardial Tamponade 11 33
Rose's Tamponade 11

Classifications:



External Ids:

Disease Ontology 11 DOID:115
ICD9CM 34 423.3
MeSH 43 D002305
NCIt 49 C50481
SNOMED-CT 68 266295005
ICD11 33 216782575
UMLS 71 C0007177

Summaries for Cardiac Tamponade

Disease Ontology: 11 A pericardial effusion in which fluid accumulates in the pericardium (the sac in which the heart is enclosed) and the pericardial spaces fills up faster than the pericardial sac can stretch.

MalaCards based summary: Cardiac Tamponade, also known as pericardial tamponade, is related to pericardial tuberculosis and cardiogenic shock. An important gene associated with Cardiac Tamponade is F8 (Coagulation Factor VIII), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs). Affiliated tissues include heart, lung and breast, and related phenotypes are homeostasis/metabolism and cardiovascular system

Wikipedia: 75 Cardiac tamponade, also known as pericardial tamponade (/ˌtæm.pəˈneɪd/), is the buildup of fluid in the... more...

Related Diseases for Cardiac Tamponade

Diseases related to Cardiac Tamponade via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 1208)
# Related Disease Score Top Affiliating Genes
1 pericardial tuberculosis 32.2 CRP ADA
2 cardiogenic shock 31.1 PLAT PIK3C2A NPPB
3 hemopericardium 31.0 TNNI3 PLG PLAT NPPB F3 F2
4 cardiac arrest 31.0 TNNI3 NPPB CRP ACE
5 heart septal defect 31.0 NPPB F3 F2 CRP
6 pericarditis 31.0 TNNI3 TNFRSF1A NPPB IL6 CRP ADA
7 aortic dissection 30.9 IL6 CRP ALB ACE
8 hemophilia 30.7 F9 F8 F2
9 vitamin k deficiency bleeding 30.6 F9 F8 F3 F2
10 juvenile rheumatoid arthritis 30.5 TNFRSF1A IL6 CRP
11 aortic valve disease 2 30.4 TNNI3 REN NPPB CRP ACE
12 hemophilia a 30.4 F9 F8 F3 F2
13 kawasaki disease 30.4 NPPB GPT CRP
14 spontaneous tension pneumothorax 30.4 NPPB GPT CRP
15 constrictive pericarditis 30.3 TNNI3 REN NPPB CRP ALB ADA
16 cardiac sarcoidosis 30.3 NPPB CRP ACE
17 toxic shock syndrome 30.3 IL6 F3 CRP
18 thrombophilia due to thrombin defect 30.3 PLAT F9 F8 F3 F2
19 third-degree atrioventricular block 30.3 TNNI3 REN NPPB CRP ACE
20 hypertension, diastolic 30.2 REN ACE
21 atrioventricular block 30.2 TNNI3 PIK3C2A NPPB CRP ACE
22 restrictive cardiomyopathy 30.2 TNNI3 REN NPPB CRP ACE
23 factor vii deficiency 30.2 F9 F8 F3 F2
24 heparin-induced thrombocytopenia 30.2 F3 F2
25 malignant hypertension 30.2 REN NPPB ACE
26 factor viii deficiency 30.2 F9 F8 F3 F2 ALB
27 familial mediterranean fever 30.1 TNFRSF1A IL6 CRP
28 rheumatic myocarditis 30.1 TNNI3 CRP
29 brucellosis 30.1 IL6 CRP ADA
30 polyarteritis nodosa 30.1 IL6 GPT CRP
31 amyloidosis 30.1 TNFRSF1A NPPB IL6 CRP ALB
32 cardiac tuberculosis 30.1 NPPB CRP ACE
33 tricuspid valve stenosis 30.1 NPPB F3
34 rheumatic fever 30.1 NPPB IL6 ALB ACE
35 uremia 30.1 REN IL6 CRP ALB ACE
36 appendicitis 30.0 IL6 CRP ALB
37 acquired immunodeficiency syndrome 30.0 TNFRSF1A IL6 F9 CRP ALB ADA
38 yellow nail syndrome 30.0 ALB ADA
39 aortic valve disease 1 30.0 REN NPPB F2 CRP ACE
40 cholecystitis 30.0 GPT F2 CRP ALB
41 antiphospholipid syndrome 30.0 PLAT F3 F2 CRP
42 nutritional deficiency disease 30.0 IL6 F2 CRP ALB
43 raynaud disease 30.0 PLAT PIK3C2A CRP
44 rheumatic heart disease 30.0 NPPB IL6 ACE
45 volvulus of midgut 30.0 GPT F3 F2 CRP ALB
46 factor v deficiency 30.0 F9 F8 F3 F2
47 factor x deficiency 30.0 F9 F8 F3 F2
48 cavernous hemangioma 30.0 F3 F2 ALB
49 hepatopulmonary syndrome 29.9 CRP ALB ACE
50 macrophage activation syndrome 29.9 TNFRSF1A IL6 CRP

Graphical network of the top 20 diseases related to Cardiac Tamponade:



Diseases related to Cardiac Tamponade

Symptoms & Phenotypes for Cardiac Tamponade

GenomeRNAi Phenotypes related to Cardiac Tamponade according to GeneCards Suite gene sharing:

25
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 no effect GR00402-S-1 10.17 ACE ADA ALB BRK1 CRP F2
2 no effect GR00402-S-2 10.17 ACE ADA ALB CRP F2 F3

MGI Mouse Phenotypes related to Cardiac Tamponade:

45 (show all 11)
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.33 ACE ADA ALB CRP F2 F3
2 cardiovascular system MP:0005385 10.27 ACE ADA ALB CRP F2 F3
3 muscle MP:0005369 10.18 ADA ALB F2 F3 IL6 NPPB
4 cellular MP:0005384 10.18 ACE ADA ALB BRK1 F2 F3
5 immune system MP:0005387 10.17 ACE ADA ALB CRP F2 F3
6 renal/urinary system MP:0005367 10.15 ACE ADA ALB GATA2 IL6 PIK3C2A
7 embryo MP:0005380 10.09 ACE ADA BRK1 F2 F3 F9
8 reproductive system MP:0005389 9.9 ACE ADA BRK1 F2 F8 GATA2
9 respiratory system MP:0005388 9.86 ADA F2 F3 IL6 PLAT PLG
10 hematopoietic system MP:0005397 9.77 ACE ADA F2 F3 F8 F9
11 mortality/aging MP:0010768 9.53 ACE ADA ALB BRK1 F2 F3

Drugs & Therapeutics for Cardiac Tamponade

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Atrial Fibrillation and Pericardial Drainage: Incidence of Postoperative Atrial Fibrillation According to the Type of Mediastinal Drainage Catheters Unknown status NCT02808897 Phase 4
2 Evaluation of Different Strategies of Pericardial Drainage After Aortic Valvular Surgery: A Prospective Randomized Trial Completed NCT00684125
3 Validation of Epworth Richmond's Echocardiography Education Focused Year Completed NCT02961439
4 The Management of Left Atrial Appendage Perforation Complicated by Cardiac Tamponade During Left Atrial Appendage Occluder Device Deployment Completed NCT05086653
5 Continuous Postoperative Pericardial Flushing After Cardiac Surgery in High Risk Patients With the Haermonics Investigational Device: Study Protocol of the FLUID (FLUsh With Investigational Device) Trial Recruiting NCT05308589

Search NIH Clinical Center for Cardiac Tamponade

Cochrane evidence based reviews: cardiac tamponade

Genetic Tests for Cardiac Tamponade

Anatomical Context for Cardiac Tamponade

Organs/tissues related to Cardiac Tamponade:

MalaCards : Heart, Lung, Breast, Bone Marrow, Liver, Lymph Node, Kidney

Publications for Cardiac Tamponade

Articles related to Cardiac Tamponade:

(show top 50) (show all 8148)
# Title Authors PMID Year
1
Cardiac tamponade in a patient with moderate hemophilia A and factor VIII Inhibitors. 53 62
16450022 2006
2
Point-of-care ultrasound use in emergencies: what every anaesthetist should know. 62
36449358 2023
3
Hematologic and Oncologic Emergencies. 62
36415070 2023
4
Potential Cardiac Tamponade Development Secondary to SARS-CoV-2 Infection. 62
36155201 2023
5
Cardiac tamponade and septic pericarditis caused by biliary stent migration. 62
36270959 2023
6
Acute cardiac tamponade secondary to nonpenetrating injury from gunshot with beanbag round: A case report and literature review. 62
36386427 2022
7
Delayed traumatic purulent pericarditis with cardiac tamponade - A rare case report. 62
36386431 2022
8
Cardiac Tamponade - a Cause of Sudden Death in a Premature Newborn. 62
34866542 2022
9
Rare case of infective aortitis with aortic rupture and cardiac tamponade in a young child. 62
36455981 2022
10
Intra-arrest transesophageal echocardiography during cardiopulmonary resuscitation. 62
36475353 2022
11
Transesophageal Echocardiography-Guided Extracorporeal Membrane Oxygenation Cannulation in COVID-19 Patients. 62
36038441 2022
12
A new trend to reduce adverse events in patients undergoing transcatheter aortic valve implantation: cusp overlap technique: a cross sectional study. 62
36460902 2022
13
Cardiac tamponade caused by intrapericardial diaphragmatic hernia. 62
36458880 2022
14
Campylobacter jejuni Pericarditis: A Case Report. 62
35482351 2022
15
TAVI With or Without Predilation: Trends From a Large, Propensity-Score Weighted German Aortic Valve Registry (GARY) Population. 62
36416901 2022
16
Sex difference in clinical and procedural outcomes in patients undergoing coronary atherectomy: a systematic review and meta-analysis. 62
36238981 2022
17
Percutaneous balloon pericardiotomy: efficacy in a series of malignant and nonmalignant cases. 62
35982636 2022
18
Myocardial Protection in Isolated Coronary Artery Bypass Grafting: Del Nido versus Blood Cardioplegia. 62
36459478 2022
19
Safety and usefulness of left ventricular endomyocardial biopsy in new- onset acute heart failure requiring mechanical support by an Impella® device. 62
35944774 2022
20
Pericardial Decompression Syndrome After Drainage of Chronic Pericardial Effusions. 62
36444176 2022
21
Simplified stepwise anatomical ablation strategy for mitral isthmus: efficacy, efficiency, safety, and outcome. 62
36353823 2022
22
Evaluation of Multimodality LAA Leak Closure Methods Following Incomplete Occlusion: The LAA Leak Study. 62
36357020 2022
23
Delayed Pericardial Effusion Following Left Atrial Appendage Closure: A 5-Year Single-Center Experience. 62
36446576 2022
24
Estimation of mechanical properties by transcatheter monitoring using local impedance and contact force. 62
36426804 2022
25
Impact of prior coronary artery bypass grafting on periprocedural and short-term outcomes of patients undergoing transcatheter aortic valve replacement: a systematic review and meta-analysis. 62
36326179 2022
26
Genetic duplication of tissue factor reveals subfunctionalization in venous and arterial hemostasis. 62
36449521 2022
27
Intra- and Postprocedural Management of Coronary Artery Perforation During Percutaneous Coronary Intervention. 62
36408355 2022
28
Predicting mortality in penetrating cardiac trauma in developing countries through a new classification: Validation of the Bogotá classification. 62
36381412 2022
29
[Safety and efficacy of high-power, short-duration superior vena cava isolation in combination with conventional radiofrequency ablation in patients with paroxysmal atrial fibrillation: a randomized controlled trial]. 62
36418274 2022
30
Feasibility and safety of laser balloon pulmonary vein isolation in patients with prior left atrial appendage occlusion device implantation. 62
36041214 2022
31
Procedural complications associated with percutaneous mitral balloon valvotomy: A systematic review. 62
36421070 2022
32
Temperature-controlled high-power short-duration ablation with 90 W for 4 s: outcome, safety, biophysical characteristics and cranial MRI findings in patients undergoing pulmonary vein isolation. 62
35748975 2022
33
Valve-Related Complications in TAVI Leading to Emergent Cardiac Surgery. 62
36446625 2022
34
A totally endoscopic approach for aortic valve surgery. 62
36165709 2022
35
Impact of Previous Infection on Perioperative Outcomes of Thoracoscopic Lobectomy for Congenital Lung Malformation. 62
36350681 2022
36
Retrospective evaluation of clinical signs, clinical course, and prognosis between dogs with left atrial rupture secondary to myxomatous mitral valve disease and those with neoplastic cardiac tamponade (2015-2019): 70 cases. 62
35960167 2022
37
Curative Pericardiectomy in Interpheron-Resistant Severe Pericardial Erdheim-Chester Disease. 62
36444187 2022
38
Real-world clinical outcomes of percutaneous transluminal septal myocardial ablation for patients with drug-refractory hypertrophic obstructive cardiomyopathy: results from a retrospective multicenter registry of non-high-volume centers. 62
35641828 2022
39
[Hypertriglyceridemic pancreatitis and cardiac tamponade in a 26-year-old woman]. 62
36418500 2022
40
Trends, predictors, and outcomes of transcatheter aortic valve implantation in patients with bicuspid aortic valve related disease: Insights from the Nationwide Inpatient Sample and Nationwide Readmission Database. 62
36183395 2022
41
Kissing Viabahn VBX stent graft reconstruction of thoracic central veins for management of superior vena cava syndrome. 62
35843595 2022
42
Outcomes of catheter ablation for ventricular tachycardia in patients with sarcoidosis: Insights from the National Inpatient Sample database (2002-2018). 62
36335632 2022
43
Hemorrhagic Cardiac Tamponade with Blood Clot Formation in Acute Aortic Dissection Despite Initial D-Dimer of < 500 ng/mL. 62
36372405 2022
44
Delayed pericardial effusion or tamponade following left atrial appendage closure: A single-center experience. 62
36463080 2022
45
Postsurgical Left Atrial Compression due to Hemopericardium Resulting in Liver Failure: A Rare Cause of Cardiac Tamponade. 62
36451873 2022
46
A Man in His 50s With Cardiac Tamponade From Ruptured Coronary Artery Aneurysm. 62
36350316 2022
47
Subacute Cardiac Tamponade Due to Tuberculous Pericarditis Diagnosed by Urine Lipoarabinomannan Assay in a Immunocompetent Patient in Oyam District, Uganda: A Case Report. 62
36429861 2022
48
Cardiac Tamponade Causing Predominant Left Atrial and Ventricular Compression After Left Ventricular Assist Device Placement. 62
36427279 2022
49
Cardiac Tamponade complicating Ventricular Arrythmia Ablation: real life data on incidence, management and outcome. 62
36434796 2022
50
Impending cardiac tamponade and coated aorta: Erdheim-Chester disease. 62
36245282 2022

Variations for Cardiac Tamponade

Expression for Cardiac Tamponade

Search GEO for disease gene expression data for Cardiac Tamponade.

Pathways for Cardiac Tamponade

Pathways related to Cardiac Tamponade according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.62 PLG PLAT GATA2 F9 F8 F3
2
Show member pathways
12.1 PLG IL6 F2 ALB
3 11.75 TNNI3 IL6 GATA2 ALB
4
Show member pathways
11.56 PLG PLAT F9 F8 F3 F2
5 11.18 PLG PLAT IL6
6 10.9 PLG PLAT IL6
7 10.69 PLG PLAT ACE
8 10.59 PLG PLAT
9
Show member pathways
10.54 F9 F8
10 10.25 PLG F2

GO Terms for Cardiac Tamponade

Cellular components related to Cardiac Tamponade according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 10.05 ACE ALB CRP F2 F3 F8
2 endoplasmic reticulum lumen GO:0005788 9.85 IL6 F9 F8 F2 ALB
3 extracellular space GO:0005615 9.75 TNFRSF1A REN PLG PLAT NPPB IL6

Biological processes related to Cardiac Tamponade according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 proteolysis GO:0006508 10.21 REN PLG PLAT F9 F2 ACE
2 acute-phase response GO:0006953 9.86 CRP F2 F8 IL6
3 fibrinolysis GO:0042730 9.85 PLG PLAT F2
4 negative regulation of fibrinolysis GO:0051918 9.8 PLG PLAT F2
5 blood coagulation GO:0007596 9.73 PLG PLAT F9 F8 F3 F2
6 trans-synaptic signaling by BDNF, modulating synaptic transmission GO:0099183 9.71 PLG PLAT
7 regulation of body fluid levels GO:0050878 9.33 F9 F8 F2
8 hemostasis GO:0007599 9.02 PLG F9 F8 F3 F2

Molecular functions related to Cardiac Tamponade according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 signaling receptor binding GO:0005102 10 REN PLG PLAT NPPB IL6 F2
2 serine-type peptidase activity GO:0008236 9.72 PLG PLAT F9 F2
3 endopeptidase activity GO:0004175 9.7 ACE F9 PLG REN
4 serine-type endopeptidase activity GO:0004252 9.65 PLG PLAT F9 F3 F2
5 peptidase activity GO:0008233 9.23 REN PLG PLAT F9 F2 ACE

Sources for Cardiac Tamponade

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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