MCID: CRD217
MIFTS: 26

Cardiac Tuberculosis

Categories: Cardiovascular diseases, Infectious diseases

Aliases & Classifications for Cardiac Tuberculosis

MalaCards integrated aliases for Cardiac Tuberculosis:

Name: Cardiac Tuberculosis 12 15 17
Tuberculosis, Cardiovascular 43 71
Cardiovascular Tuberculosis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0060570
MeSH 43 D014381
UMLS 71 C0041308

Summaries for Cardiac Tuberculosis

Disease Ontology : 12 A tuberculosis located in the heart.

MalaCards based summary : Cardiac Tuberculosis, also known as tuberculosis, cardiovascular, is related to atrioventricular block and acute myocarditis. An important gene associated with Cardiac Tuberculosis is ACE (Angiotensin I Converting Enzyme), and among its related pathways/superpathways is Agents Acting on the Renin-Angiotensin System Pathway, Pharmacodynamics. The drugs Isoniazid and Antitubercular Agents have been mentioned in the context of this disorder. Affiliated tissues include heart and small intestine.

Related Diseases for Cardiac Tuberculosis

Diseases related to Cardiac Tuberculosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 165)
# Related Disease Score Top Affiliating Genes
1 atrioventricular block 29.8 NPPB ACE
2 acute myocarditis 29.3 NPPB CRP ACE
3 lung disease 29.2 NPPB CRP ACE
4 myocardial infarction 28.3 NR3C2 NPPB CRP ACE
5 mediastinum teratoma 10.2 CRP ACE
6 acute dacryoadenitis 10.2 CRP ACE
7 posterior scleritis 10.2 CRP ACE
8 tolosa-hunt syndrome 10.2 CRP ACE
9 multiple cranial nerve palsy 10.2 CRP ACE
10 cranial nerve palsy 10.2 CRP ACE
11 granulomatous angiitis 10.2 CRP ACE
12 neuroretinitis 10.2 CRP ACE
13 silent myocardial infarction 10.2 CRP ACE
14 cholesterol embolism 10.2 CRP ACE
15 optic papillitis 10.2 CRP ACE
16 generalized atherosclerosis 10.2 CRP ACE
17 intracranial embolism 10.2 CRP ACE
18 cat-scratch disease 10.2 CRP ACE
19 neurosarcoidosis 10.2 CRP ACE
20 hypertensive retinopathy 10.2 CRP ACE
21 scleral disease 10.2 CRP ACE
22 iritis 10.2 CRP ACE
23 background diabetic retinopathy 10.2 CRP ACE
24 iridocyclitis 10.2 CRP ACE
25 cerebral atherosclerosis 10.2 CRP ACE
26 coronary artery vasospasm 10.2 CRP ACE
27 raynaud disease 10.2 CRP ACE
28 chronic pyelonephritis 10.2 CRP ACE
29 pyelonephritis 10.2 CRP ACE
30 papilledema 10.2 CRP ACE
31 facial nerve disease 10.2 CRP ACE
32 facial paralysis 10.2 CRP ACE
33 drug allergy 10.2 CRP ACE
34 ischemic colitis 10.2 CRP ACE
35 hypersensitivity vasculitis 10.2 CRP ACE
36 pyelitis 10.2 CRP ACE
37 hypersensitivity reaction type iii disease 10.2 CRP ACE
38 maturity-onset diabetes of the young, type 1 10.2 CRP ACE
39 coronary thrombosis 10.2 CRP ACE
40 aspiration pneumonia 10.2 CRP ACE
41 toxic myocarditis 10.2 NPPB ACE
42 mycoplasma pneumoniae pneumonia 10.2 CRP ACE
43 anterolateral myocardial infarction 10.2 NPPB ACE
44 panuveitis 10.2 CRP ACE
45 intermediate coronary syndrome 10.2 CRP ACE
46 retinal artery occlusion 10.2 CRP ACE
47 acute pyelonephritis 10.2 CRP ACE
48 endocardium disease 10.2 CRP ACE
49 coronavirus infectious disease 10.2 CRP ACE
50 third-degree atrioventricular block 10.1 NPPB ACE

Graphical network of the top 20 diseases related to Cardiac Tuberculosis:



Diseases related to Cardiac Tuberculosis

Symptoms & Phenotypes for Cardiac Tuberculosis

Drugs & Therapeutics for Cardiac Tuberculosis

Drugs for Cardiac Tuberculosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 7)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Isoniazid Approved, Investigational 54-85-3 3767
2 Antitubercular Agents
3 Anti-Infective Agents
4 Anti-Bacterial Agents
5 Lipid Regulating Agents
6 Hypolipidemic Agents
7 Antimetabolites

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Randomized Study of Interventions to Enhance Adherence to Isoniazid Prevention Therapy for Tuberculosis in Injection Drug Users Unknown status NCT00004740 isoniazid

Search NIH Clinical Center for Cardiac Tuberculosis

Cochrane evidence based reviews: tuberculosis, cardiovascular

Genetic Tests for Cardiac Tuberculosis

Anatomical Context for Cardiac Tuberculosis

MalaCards organs/tissues related to Cardiac Tuberculosis:

40
Heart, Small Intestine

Publications for Cardiac Tuberculosis

Articles related to Cardiac Tuberculosis:

(show all 25)
# Title Authors PMID Year
1
Serum angiotensin converting enzyme, Erythrocyte sedimentation rate and high sensitive-C reactive protein levels in diagnosis of cardiac sarcoidosis- where do we stand? 61
32407763 2020
2
Association of Silica Dust Exposure and Cigarette Smoking With Mortality Among Mine and Pottery Workers in China. 61
32286660 2020
3
Acute myocarditis secondary to cardiac tuberculosis: a case report. 61
28814447 2017
4
Assessing the burden of medical impoverishment by cause: a systematic breakdown by disease in Ethiopia. 61
27769296 2016
5
An unusual cardiac mass: Echocardiography, computed tomography, and magnetic resonance imaging. 61
30546629 2016
6
Determinants of Restrictive Spirometric Pattern in a Sub-Saharan Urban Setting: A Cross-sectional Population-based Study. 61
28144367 2016
7
Patterns of mortality in public and private hospitals of Addis Ababa, Ethiopia. 61
23167315 2012
8
Loss of left ventricular torsion as the predominant mechanism of left ventricular systolic dysfunction in a patient with tubercular cardiomyopathy. 61
22748130 2012
9
A rare disappearing right atrial mass. 61
22535544 2012
10
Intracardiac left atrial tuberculoma in an eleven-month-old infant: case report. 61
22208878 2011
11
Diffuse infiltrative cardiac tuberculosis. 61
21677817 2011
12
Bicaval obstruction complicating right atrial tuberculoma: the diagnostic value of cardiovascular MR. 61
19099600 2008
13
Cardiac tuberculosis with multiple intracardiac masses: a case report. 61
12094179 2002
14
Cardiac tuberculosis presenting as small intestinal gangrene. 61
12036536 2002
15
Bloody pericardial effusion in patients with cardiac tamponade: is the cause cancerous, tuberculous, or iatrogenic in the 1990s? 61
10593777 1999
16
Images in cardiovascular medicine. Cardiac tuberculosis. 61
9715867 1998
17
[Isolated tuberculosis of the heart: a clinical and echocardiography follow-up]. 61
9133119 1997
18
Recurrence of two myocardial aneurysms infected with tuberculosis after a previous aneurysmectomy. 61
2805463 1989
19
Cardiac tuberculosis. A study of 19 patients. 61
3566473 1987
20
Medical aspects of head and neck cancer. 61
4052833 1985
21
Cardiac tuberculosis: TB of the endocardium. 61
6731481 1984
22
[Myocobacterium tuberculosis endomyocarditis. Apropos of a case in a patient with a mitral valve prosthesis]. 61
6818922 1982
23
[Cardiac tuberculosis]. 61
13484939 1957
24
[Cardiac tuberculosis simulating myocardial infarction]. 61
14891260 1951
25
Some aspects of the pathogenesis of cardiac tuberculosis. 61
20254319 1947

Variations for Cardiac Tuberculosis

Expression for Cardiac Tuberculosis

Search GEO for disease gene expression data for Cardiac Tuberculosis.

Pathways for Cardiac Tuberculosis

Pathways related to Cardiac Tuberculosis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
10.53 NR3C2 ACE

GO Terms for Cardiac Tuberculosis

Biological processes related to Cardiac Tuberculosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of blood pressure GO:0008217 8.96 NPPB ACE
2 regulation of blood vessel diameter GO:0097746 8.62 NPPB ACE

Sources for Cardiac Tuberculosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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