MCID: CRD137
MIFTS: 51

Cardiogenic Shock

Categories: Blood diseases, Cardiovascular diseases, Rare diseases

Aliases & Classifications for Cardiogenic Shock

MalaCards integrated aliases for Cardiogenic Shock:

Name: Cardiogenic Shock 59 63
Shock, Cardiogenic 73
Shock Cardiogenic 55

Characteristics:

Orphanet epidemiological data:

59
cardiogenic shock
Prevalence: 1-5/10000 (Europe);

Classifications:



External Ids:

Orphanet 59 ORPHA97292
UMLS via Orphanet 74 C0036980
ICD10 via Orphanet 34 R57.0
ICD10 33 R57.0
UMLS 73 C0036980

Summaries for Cardiogenic Shock

PubMed Health : 63 About cardiogenic shock: Cardiogenic (kar-dee-oh-JE-nik) shock is a condition in which a suddenly weakened heart isn't able to pump enough blood to meet the body's needs. The condition is a medical emergency and is fatal if not treated right away.The most common cause of cardiogenic shock is damage to the heart muscle from a severe heart attack. However, not everyone who has a heart attack has cardiogenic shock. In fact, on average, only about 7 percent of people who have heart attacks develop the condition.If cardiogenic shock does occur, it's very dangerous. When people die from heart attacks in hospitals, cardiogenic shock is the most common cause of death.

MalaCards based summary : Cardiogenic Shock, also known as shock, cardiogenic, is related to myocardial infarction and acute myocardial infarction, and has symptoms including syncope and shock without mention of trauma. An important gene associated with Cardiogenic Shock is NPPB (Natriuretic Peptide B), and among its related pathways/superpathways are Selenium Micronutrient Network and Dendritic Cells Developmental Lineage Pathway. Affiliated tissues include heart, kidney and liver.

Wikipedia : 76 Cardiogenic shock is a medical emergency resulting from inadequate blood flow due to the dysfunction of... more...

Related Diseases for Cardiogenic Shock

Diseases related to Cardiogenic Shock via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 297)
# Related Disease Score Top Affiliating Genes
1 myocardial infarction 31.8 IL6 NPPB PIK3C2A PLAT TNF
2 acute myocardial infarction 31.2 NPPB PIK3C2A PLAT
3 myocarditis 30.7 IL6 NPPB TNF
4 atrioventricular block 30.5 NPPB PIK3C2A
5 anterolateral myocardial infarction 30.2 NPPB PLAT
6 pulmonary embolism 30.1 NPPB PLAT
7 inferior myocardial infarction 30.1 NPPB PIK3C2A PLAT
8 scorpion envenomation 30.1 IL6 TNF
9 kawasaki disease 30.0 IL6 NPPB TNF
10 coronary stenosis 30.0 IL6 NPPB PIK3C2A
11 coronary artery anomaly 30.0 NPPB PIK3C2A PLAT
12 pneumonia 29.9 IL6 PIK3C2A TNF
13 limb ischemia 29.8 IL6 TNF
14 pulmonary edema 29.8 NPPB PIK3C2A TNF
15 fasciitis 29.8 IL6 TNF
16 infective endocarditis 29.8 IL6 TNF
17 acute respiratory distress syndrome 29.8 IL6 TNF
18 takayasu arteritis 29.7 IL6 TNF
19 endocarditis 29.7 IL6 PIK3C2A PLAT TNF
20 arteries, anomalies of 29.7 IL6 NPPB PLAT TNF
21 purpura 29.6 IL6 TNF
22 pericarditis 29.6 IL6 NPPB TNF
23 leptospirosis 29.6 IL6 PIK3C2A TNF
24 cardiac tamponade 11.6
25 ogden syndrome 11.2
26 hypoplastic left heart syndrome 11.2
27 cardiac arrest 10.6
28 ischemia 10.5
29 pheochromocytoma 10.4
30 thrombosis 10.4
31 mitral valve insufficiency 10.4
32 atrial standstill 1 10.2
33 adrenal gland pheochromocytoma 10.2
34 acute myocarditis 10.2
35 peripartum cardiomyopathy 10.2
36 aortic valve insufficiency 10.2
37 toxic myocarditis 10.1 NPPB PIK3C2A
38 ventricular fibrillation, paroxysmal familial, 1 10.1
39 paraganglioma 10.1
40 churg-strauss syndrome 10.1
41 influenza 10.1
42 allergic angiitis 10.1
43 systolic heart failure 10.1 IL6 NPPB
44 vibrio vulnificus infection 10.1 IL6 PIK3C2A
45 otitis media 10.1 IL6 TNF
46 cerebral palsy 10.1 IL6 TNF
47 glucose metabolism disease 10.1 IL6 TNF
48 peritonitis 10.1 IL6 TNF
49 monocytic leukemia 10.1 IL6 TNF
50 hemorrhagic fever 10.1 IL6 TNF

Comorbidity relations with Cardiogenic Shock via Phenotypic Disease Network (PDN): (show all 19)


Active Peptic Ulcer Disease Acute Cystitis
Acute Kidney Failure Aortic Valve Disease 1
Cardiac Arrest Chronic Kidney Failure
Chronic Myocardial Ischemia Deficiency Anemia
Familial Atrial Fibrillation Heart Disease
Intermediate Coronary Syndrome Ischemic Heart Disease
Kidney Disease Mitral Valve Disease
Peripheral Vascular Disease Respiratory Failure
Third-Degree Atrioventricular Block Tricuspid Valve Disease
Ventricular Fibrillation, Paroxysmal Familial, 1

Graphical network of the top 20 diseases related to Cardiogenic Shock:



Diseases related to Cardiogenic Shock

Symptoms & Phenotypes for Cardiogenic Shock

UMLS symptoms related to Cardiogenic Shock:


syncope, shock without mention of trauma

Drugs & Therapeutics for Cardiogenic Shock

PubMedHealth treatment related to Cardiogenic Shock: 63

Cardiogenic shock is life threatening and requires emergency medical treatment. The condition usually is diagnosed after a person has been admitted to a hospital for a heart attack. If the person isn't already in a hospital, emergency treatment can start as soon as medical personnel arrive.The first goal of emergency treatment for cardiogenic shock is to improve the flow of blood and oxygen to the body’s organs.Sometimes both the shock and its cause are treated at the same time. For example, doctors may quickly open a blocked blood vessel that's damaging the heart. Often, this can get the patient out of shock with little or no additional treatment.

Search Clinical Trials , NIH Clinical Center for Cardiogenic Shock

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Genetic Tests for Cardiogenic Shock

Anatomical Context for Cardiogenic Shock

MalaCards organs/tissues related to Cardiogenic Shock:

41
Heart, Kidney, Liver, Bone, Skeletal Muscle, Endothelial, Lung

Publications for Cardiogenic Shock

Articles related to Cardiogenic Shock:

(show top 50) (show all 1459)
# Title Authors Year
1
MicroRNAs in pathophysiology of acute myocardial infarction and cardiogenic shock. ( 29947233 )
2018
2
Optimal course of treatment in acute cardiogenic shock complicating myocardial infarction. ( 29310471 )
2018
3
National Trends, Predictors of Use, and In-Hospital Outcomes in the Mechanical Circulatory Support for Cardiogenic Shock. ( 29400657 )
2018
4
Cardiogenic shock complicating peripartum cardiomyopathy: Importance of early left ventricular unloading and bromocriptine therapy. ( 29792513 )
2018
5
Acute heart failure following myocardial infarction: complement activation correlates with the severity of heart failure in patients developing cardiogenic shock. ( 29424484 )
2018
6
Norepinephrine as a First-Line Inopressor in Cardiogenic Shock: Oversimplification or Best Practice? ( 29976292 )
2018
7
The Use of ECMO for the Treatment of Refractory Cardiac Arrest or Postarrest Cardiogenic Shock Following In-Hospital Cardiac Arrest: A 10-Year Experience. ( 29303029 )
2018
8
Hospital mortality and thirty day readmission among patients with non-acute myocardial infarction related cardiogenic shock. ( 29929933 )
2018
9
A Targeted Management Approach to Cardiogenic Shock. ( 29907274 )
2018
10
Revascularization strategies in cardiogenic shock complicating acute myocardial infarction: A systematic review and meta-analysis. ( 29909948 )
2018
11
Outcome after revascularisation of acute myocardial infarction with cardiogenic shock on extracorporeal life support. ( 29400656 )
2018
12
Three-Dimensional Inferior Vena Cava for Assessing Central Venous Pressure in Patients with Cardiogenic Shock. ( 29908724 )
2018
13
Inotropic agents and vasodilator strategies for the treatment of cardiogenic shock or low cardiac output syndrome. ( 29376560 )
2018
14
Cardiogenic Shock: A Rare Complication of Influenza. ( 29963343 )
2018
15
Implementation of a Cardiogenic Shock Team and Clinical Outcomes (INOVA-SHOCK Registry): Observational and Retrospective Study. ( 29954728 )
2018
16
A Right Insight in Cardiogenic Shock to Get It Right. ( 29374583 )
2018
17
Cardiogenic Shock: An Unusual Initial Presentation of Churg-Strauss Syndrome. ( 29808153 )
2018
18
Adenosine Plasma Level and A2A Receptor Expression in Patients With Cardiogenic Shock. ( 29923934 )
2018
19
Re. Multivessel Percutaneous Coronary Intervention in Patients With ST-Segment Elevation Myocardial Infarction with Cardiogenic Shock. ( 29958193 )
2018
20
Comparison of temporary ventricular assist devices and extracorporeal life support in post-cardiotomy cardiogenic shock. ( 29905854 )
2018
21
Mortality in patients with cardiogenic shock treated with the Impella CP microaxial pump for isolated left ventricular failure. ( 29405734 )
2018
22
Tako-tsubo Cardiomyopathy Complicated With Cardiac Tamponade and Cardiogenic Shock. ( 29844005 )
2018
23
Vascular complications in adult postcardiotomy cardiogenic shock patients receiving venoarterial extracorporeal membrane oxygenation. ( 29916091 )
2018
24
Is index procedure complete revascularization really essential for ST-elevation myocardial infarction with cardiogenic shock? ( 29430782 )
2018
25
Veno-arterial extracorporeal membrane oxygenation as a bridge for enabling surgery in a patient under cardiogenic shock due to acute mitral prosthesis dysfunction. ( 29910584 )
2018
26
ECMO use and mortality in adult patients with cardiogenic shock: a retrospective observational study in U.S. hospitals. ( 29973150 )
2018
27
Blood lactate is a predictor of short-term mortality in patients with myocardial infarction complicated by heart failure but without cardiogenic shock. ( 29347907 )
2018
28
Plasma Concentration of Biomarkers Reflecting Endothelial Cell- and Glycocalyx Damage are Increased in Patients with Suspected St-Elevation Myocardial Infarction Complicated by Cardiogenic Shock. ( 29438221 )
2018
29
Reply: Revascularization Strategies in Patients With Acute MI and Cardiogenic Shock. ( 29929627 )
2018
30
Mechanical support in cardiogenic shock complicating acute coronary syndrome: ready for prime time? ( 29345584 )
2018
31
Cardiogenic shock: the next frontier in acute cardiovascular care! ( 29412021 )
2018
32
Assessment of Safety and Effectiveness of the Extracorporeal Continuous-Flow Ventricular Assist Device (BR16010) Use as a Bridge-to-Decision Therapy for Severe Heart Failure or Refractory Cardiogenic Shock: Study Protocol for Single-Arm Non-randomized, Uncontrolled, and Investigator-Initiated Clinical Trial. ( 29948739 )
2018
33
Revascularization Strategies in Patients With Acute MI and Cardiogenic Shock. ( 29929626 )
2018
34
Revision: prognostic impact of baseline glucose levels in acute myocardial infarction complicated by cardiogenic shock-a substudy of the IABP-SHOCK II-trial. ( 29423774 )
2018
35
Predictive Value of Procalcitonin for Infection and Survival in Adult Cardiogenic Shock Patients Treated with Extracorporeal Membrane Oxygenation. ( 29399566 )
2018
36
'Combat' Approach to Cardiogenic Shock. ( 29928313 )
2018
37
Extracorporeal life support in cardiogenic shock: indications and management in current practice. ( 29349674 )
2018
38
Epinephrine Versus Norepinephrine forA Cardiogenic Shock After AcuteA Myocardial Infarction. ( 29976291 )
2018
39
Cardiogenic shock and tako-tsubo cardiomyopathy in a 9-year-old girl with retroperitoneal paraganglioma. ( 29903891 )
2018
40
Regarding "Incidence and risk factors of groin lymphocele formation after venoarterial extracorporeal membrane oxygenation in cardiogenic shock patients". ( 29579476 )
2018
41
Early Electroencephalography Findings in Cardiogenic Shock Patients Treated by Venoarterial Extracorporeal Membrane Oxygenation. ( 29389771 )
2018
42
Real-life use of left ventricular circulatory support with Impella in cardiogenic shock after acute myocardial infarction: 12 years AMC experience. ( 30403366 )
2018
43
Meta-analysis Comparing Culprit Vessel Only Versus Multivessel Percutaneous Coronary Intervention in Patients With Acute Myocardial Infarction and Cardiogenic Shock. ( 30420183 )
2018
44
Long term survival after early unloading with Impella CP® in acute myocardial infarction complicated by cardiogenic shock. ( 30456984 )
2018
45
The role of different mechanical circulatory support devices and their timing of implantation on myocardial damage and mid-term recovery in acute myocardial infarction related cardiogenic shock. ( 30460719 )
2018
46
Late and fatal onset of Kawasaki disease: Acute myocardial infarction complicated with cardiogenic shock as a late onset of Kawasaki disease. ( 30553629 )
2018
47
Temporal Trends in Utilization of Right-Sided Heart Catheterization Among Percutaneous Ventricular Assist Device Recipients in Acute Myocardial Infarction Complicated by Cardiogenic Shock. ( 30297267 )
2018
48
In-hospital mortality of patients with cardiogenic shock after acute myocardial infarction; impact of early revascularization. ( 30309379 )
2018
49
How to manage chronic total occlusions in the setting of acute myocardial infarction complicated by cardiogenic shock? ( 30312996 )
2018
50
Acute Myocardial Infarction Due to Multiple Thrombosis without Cardiogenic Shock. ( 30380556 )
2018

Variations for Cardiogenic Shock

Expression for Cardiogenic Shock

Search GEO for disease gene expression data for Cardiogenic Shock.

Pathways for Cardiogenic Shock

Pathways related to Cardiogenic Shock according to GeneCards Suite gene sharing:

(show all 19)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.83 IL6 PLAT TNF
2 11.45 IL6 TNF
3 11.43 IL6 TNF
4 11.37 IL6 TNF
5
Show member pathways
11.36 IL6 TNF
6 11.29 IL6 TNF
7 11.24 IL6 TNF
8
Show member pathways
11.23 IL6 PLAT TNF
9 11.21 IL6 TNF
10 11.2 IL6 TNF
11 11.15 IL6 TNF
12 11.02 IL6 TNF
13 11 IL6 TNF
14 10.94 IL6 TNF
15 10.9 IL6 TNF
16 10.83 IL6 TNF
17 10.6 IL6 TNF
18 10.48 IL6 PLAT TNF
19 10.43 IL6 TNF

GO Terms for Cardiogenic Shock

Biological processes related to Cardiogenic Shock according to GeneCards Suite gene sharing:

(show all 12)
# Name GO ID Score Top Affiliating Genes
1 regulation of signaling receptor activity GO:0010469 9.69 IL6 NPPB TNF
2 response to glucocorticoid GO:0051384 9.49 IL6 TNF
3 positive regulation of interleukin-6 production GO:0032755 9.48 IL6 TNF
4 humoral immune response GO:0006959 9.46 IL6 TNF
5 positive regulation of smooth muscle cell proliferation GO:0048661 9.43 IL6 TNF
6 negative regulation of fat cell differentiation GO:0045599 9.4 IL6 TNF
7 platelet-derived growth factor receptor signaling pathway GO:0048008 9.37 PIK3C2A PLAT
8 negative regulation of neurogenesis GO:0050768 9.32 IL6 TNF
9 positive regulation of chemokine production GO:0032722 9.26 IL6 TNF
10 positive regulation of glial cell proliferation GO:0060252 9.16 IL6 TNF
11 negative regulation of lipid storage GO:0010888 8.96 IL6 TNF
12 positive regulation of neuroinflammatory response GO:0150078 8.62 IL6 TNF

Sources for Cardiogenic Shock

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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