MCID: CRD137
MIFTS: 42

Cardiogenic Shock

Categories: Blood diseases, Cardiovascular diseases, Rare diseases

Aliases & Classifications for Cardiogenic Shock

MalaCards integrated aliases for Cardiogenic Shock:

Name: Cardiogenic Shock 60 64
Shock, Cardiogenic 74
Shock Cardiogenic 56

Characteristics:

Orphanet epidemiological data:

60
cardiogenic shock
Prevalence: 1-5/10000 (Europe);

Classifications:



External Ids:

ICD10 34 R57.0
ICD10 via Orphanet 35 R57.0
UMLS via Orphanet 75 C0036980
Orphanet 60 ORPHA97292
UMLS 74 C0036980

Summaries for Cardiogenic Shock

PubMed Health : 64 About cardiogenic shock: Cardiogenic (kar-dee-oh-JE-nik) shock is a condition in which a suddenly weakened heart isn't able to pump enough blood to meet the body's needs. The condition is a medical emergency and is fatal if not treated right away.The most common cause of cardiogenic shock is damage to the heart muscle from a severe heart attack. However, not everyone who has a heart attack has cardiogenic shock. In fact, on average, only about 7 percent of people who have heart attacks develop the condition.If cardiogenic shock does occur, it's very dangerous. When people die from heart attacks in hospitals, cardiogenic shock is the most common cause of death.

MalaCards based summary : Cardiogenic Shock, also known as shock, cardiogenic, is related to myocardial infarction and acute myocardial infarction, and has symptoms including syncope and shock without mention of trauma. An important gene associated with Cardiogenic Shock is NPPB (Natriuretic Peptide B), and among its related pathways/superpathways are Microglia Activation During Neuroinflammation: Overview and Senescence and Autophagy in Cancer. Affiliated tissues include heart, liver and kidney.

Wikipedia : 77 Cardiogenic shock (CS) is a medical emergency resulting from inadequate blood flow due to the... more...

Related Diseases for Cardiogenic Shock

Diseases related to Cardiogenic Shock via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 198)
# Related Disease Score Top Affiliating Genes
1 myocardial infarction 31.3 ADM IL6 NPPB PIK3C2A PLAT
2 acute myocardial infarction 31.2 NPPB PIK3C2A PLAT
3 myocarditis 31.1 IL6 NPPB
4 cardiac arrest 31.0 NPPB PIK3C2A
5 congestive heart failure 30.5 ADM NPPB
6 atrioventricular block 30.5 NPPB PIK3C2A
7 pulmonary edema 30.3 NPPB PIK3C2A
8 ischemic heart disease 30.3 IL6 NPPB
9 kawasaki disease 30.3 IL6 NPPB
10 pulmonary embolism 30.2 NPPB PLAT
11 anterolateral myocardial infarction 30.1 NPPB PLAT
12 pericarditis 30.1 IL6 NPPB
13 coronary stenosis 30.1 IL6 NPPB PIK3C2A
14 arteries, anomalies of 30.1 IL6 NPPB PLAT
15 coronary artery anomaly 30.1 NPPB PIK3C2A PLAT
16 pneumonia 29.9 IL6 PIK3C2A
17 inferior myocardial infarction 29.9 NPPB PIK3C2A PLAT
18 endocarditis 29.8 IL6 PIK3C2A PLAT
19 leptospirosis 29.8 IL6 PIK3C2A
20 pulmonary hypertension, primary, 1 29.8 ADM NPPB
21 peripheral vascular disease 29.5 IL6 PLAT
22 pulmonary hypertension 29.4 ADM NPPB PLAT
23 heart disease 28.8 ADM IL6 NPPB PIK3C2A PLAT
24 cardiac tamponade 11.6
25 ogden syndrome 11.3
26 rere-related disorders 10.7
27 ischemia 10.7
28 pheochromocytoma 10.6
29 mitral valve insufficiency 10.6
30 adrenal gland pheochromocytoma 10.6
31 thrombosis 10.5
32 atrial standstill 1 10.5
33 broken heart syndrome 10.5
34 ventricular fibrillation, paroxysmal familial, 1 10.3
35 hypertrophic cardiomyopathy 10.3
36 acute myocarditis 10.3
37 influenza 10.3
38 coronary thrombosis 10.2
39 peripartum cardiomyopathy 10.2
40 diabetes mellitus 10.2
41 aortic valve insufficiency 10.2
42 eosinophilic granulomatosis with polyangiitis 10.2
43 systemic lupus erythematosus 10.1
44 myxedema 10.1
45 infantile liver failure syndrome 1 10.1
46 dilated cardiomyopathy 10.1
47 paraganglioma 10.1
48 lymphoma 10.1
49 coronary artery vasospasm 10.1
50 ventricular septal defect 10.1

Comorbidity relations with Cardiogenic Shock via Phenotypic Disease Network (PDN): (show all 19)


Active Peptic Ulcer Disease Acute Cystitis
Acute Kidney Failure Aortic Valve Disease 1
Cardiac Arrest Chronic Kidney Failure
Chronic Myocardial Ischemia Deficiency Anemia
Familial Atrial Fibrillation Heart Disease
Intermediate Coronary Syndrome Ischemic Heart Disease
Kidney Disease Mitral Valve Disease
Peripheral Vascular Disease Respiratory Failure
Third-Degree Atrioventricular Block Tricuspid Valve Disease
Ventricular Fibrillation, Paroxysmal Familial, 1

Graphical network of the top 20 diseases related to Cardiogenic Shock:



Diseases related to Cardiogenic Shock

Symptoms & Phenotypes for Cardiogenic Shock

UMLS symptoms related to Cardiogenic Shock:


syncope, shock without mention of trauma

Drugs & Therapeutics for Cardiogenic Shock

PubMedHealth treatment related to Cardiogenic Shock: 64

Cardiogenic shock is life threatening and requires emergency medical treatment. The condition usually is diagnosed after a person has been admitted to a hospital for a heart attack. If the person isn't already in a hospital, emergency treatment can start as soon as medical personnel arrive.The first goal of emergency treatment for cardiogenic shock is to improve the flow of blood and oxygen to the body’s organs.Sometimes both the shock and its cause are treated at the same time. For example, doctors may quickly open a blocked blood vessel that's damaging the heart. Often, this can get the patient out of shock with little or no additional treatment.

Search Clinical Trials , NIH Clinical Center for Cardiogenic Shock

Inferred drug relations via UMLS 74 / NDF-RT 52 :


Genetic Tests for Cardiogenic Shock

Anatomical Context for Cardiogenic Shock

MalaCards organs/tissues related to Cardiogenic Shock:

42
Heart, Liver, Kidney, Lung, Endothelial, Brain, Tongue

Publications for Cardiogenic Shock

Articles related to Cardiogenic Shock:

(show top 50) (show all 2769)
# Title Authors Year
1
Extracorporeal Life Support in Cardiogenic Shock Complicating Acute Myocardial Infarction. ( 31072581 )
2019
2
Cardiogenic Shock in Takotsubo Cardiomyopathy Versus Acute Myocardial Infarction: An 8-Year National Perspective on Clinical Characteristics, Management, and Outcomes. ( 31078481 )
2019
3
Revascularization strategies in cardiogenic shock after acute myocardial infarction. ( 31082824 )
2019
4
Rebuttal: Response to letter by Desch et al. regarding "Outcomes of multivessel vs. culprit lesion-only percutaneous coronary intervention in patients with acute myocardial infarction complicated by cardiogenic shock: Evidence from an updated meta-analysis". ( 31090240 )
2019
5
Letter commenting on: Outcomes of multivessel vs culprit lesion-only percutaneous coronary intervention in patients with acute myocardial infarction complicated by cardiogenic shock: Evidence from an updated meta-analysis (Kundu et al. Catheter Cardiovasc Interv. 2018 Dec 28. [epub ahead of print]). ( 31090250 )
2019
6
Cardiogenic Shock Following Acute Myocardial Infarction: What's New? ( 31090679 )
2019
7
Clinical outcomes of second-generation limus-eluting stents compared to paclitaxel-eluting stents for acute myocardial infarction with cardiogenic shock. ( 30943217 )
2019
8
Mechanical circulatory support for refractory cardiogenic shock post-acute myocardial infarction-a decade of lessons. ( 30962998 )
2019
9
Acute Noncardiac Organ Failure in Acute Myocardial Infarction With Cardiogenic Shock. ( 30975295 )
2019
10
Letter to the editor regarding the results of the retrospective study "Predictors of intra-aortic balloon pump hemodynamic failure in non-acute myocardial infarction cardiogenic shock" published in the American Heart Journal. ( 30982544 )
2019
11
Impella use in acute myocardial infarction complicated by cardiogenic shock and cardiac arrest : Analysis of 10 years registry data. ( 31009694 )
2019
12
Extracorporeal life support in the multidisciplinary management of cardiogenic shock complicating acute myocardial infarction. ( 31037816 )
2019
13
Prospective Comparison of a Percutaneous Ventricular Assist Device and Venoarterial Extracorporeal Membrane Oxygenation for Patients With Cardiogenic Shock Following Acute Myocardial Infarction. ( 31041870 )
2019
14
Cardiogenic shock due to sexually transmitted disease - A rare cause of acute myocardial infarction. ( 30744822 )
2019
15
Outcomes Among Patients Transferred for Revascularization With Impella for Acute Myocardial Infarction With Cardiogenic Shock from the cVAD Registry. ( 30777319 )
2019
16
Correction to: Prevention of Cardiogenic Shock After Acute Myocardial Infarction. ( 30802170 )
2019
17
Frequency of 30-day readmission and its causes after percutaneous coronary intervention in acute myocardial infarction complicated by cardiogenic shock. ( 30811833 )
2019
18
Management of cardiogenic shock complicating acute myocardial infarction: A review. ( 30815887 )
2019
19
Successful Re-Initiation of Therapeutic Hypothermia as Adjunctive Salvage Therapy in a Case of Refractory Cardiogenic Shock Due to Acute Myocardial Infarction. ( 30858348 )
2019
20
Temporal trends and outcomes of prolonged invasive mechanical ventilation and tracheostomy use in acute myocardial infarction with cardiogenic shock in the United States. ( 30871802 )
2019
21
Correction to: Another Nail in the Coffin for Intra-Aortic Balloon Counterpulsion in Acute Myocardial Infarction With Cardiogenic Shock. ( 30640539 )
2019
22
Outcomes of Hemodynamic Support With Impella for Acute Myocardial Infarction Complicated by Cardiogenic Shock at a Rural Community Hospital Without On-Site Surgical Back-up. ( 30700627 )
2019
23
Acute Myocardial Infarction due to Multiple Thrombosis without Cardiogenic Shock. ( 30380556 )
2019
24
Meta-analysis Comparing Culprit Vessel Only Versus Multivessel Percutaneous Coronary Intervention in Patients With Acute Myocardial Infarction and Cardiogenic Shock. ( 30420183 )
2019
25
Vasopressors for acute myocardial infarction complicated by cardiogenic shock. ( 29204662 )
2019
26
ACUTE MYOCARDITIS WITH CARDIOGENIC SHOCK AND MULTIPLE ORGAN FAILURE, FOLLOWED BY BILATERAL PANUVEITIS MASQUERADING AS ENDOGENOUS ENDOPHTHALMITIS, DUE TO TOXOPLASMA GONDII IN AN IMMUNOCOMPETENT PATIENT. ( 30664080 )
2019
27
Outcomes of Coronary Artery Bypass Grafting after Extracorporeal Life Support in Patients with Cardiac Arrest or Cardiogenic Shock. ( 31089443 )
2019
28
Markers of cardiogenic shock predict persistent acute kidney injury after out of hospital cardiac arrest. ( 30470603 )
2019
29
Tako-tsubo Cardiomyopathy Complicated With Cardiac Tamponade and Cardiogenic Shock. ( 29844005 )
2019
30
Bail-Out Alcohol Septal Ablation for Hypertrophic Obstructive Cardiomyopathy in a Patient With Takotsubo Cardiomyopathy-Induced Cardiogenic Shock. ( 30722691 )
2019
31
Revascularization in Cardiogenic Shock and Advanced Heart Failure. ( 30729357 )
2019
32
Current Use and Impact on 30-Day Mortality of Pulmonary Artery Catheter in Cardiogenic Shock Patients: Results From the CardShock Study. ( 30732522 )
2019
33
Hypersensitivity Myocarditis and Necrotizing Coronary Vasculitis by Clomipramine Causing Steroid-Sensitive Cardiogenic Shock. ( 30744394 )
2019
34
Stress-Induced Cardiomyopathy Complicated by Dynamic Left Ventricular Outflow Obstruction, Cardiogenic Shock, and Ventricular Septal Rupture. ( 30760435 )
2019
35
Left Ventricular Unloading During Extracorporeal Membrane Oxygenation in Patients With Cardiogenic Shock. ( 30765031 )
2019
36
Unloading Is Not the Only Question in Cardiogenic Shock. ( 30765032 )
2019
37
Outcomes in Cardiogenic Shock from Acute Coronary Syndrome Depending on Severity of Obesity. ( 30773250 )
2019
38
Cangrelor in Cardiogenic Shock and after Cardiopulmonary Resuscitation: A Global, Multicenter, Matched Pair Analysis with Oral P2Y12 Inhibition from the IABP-SHOCK II Trial. ( 30790690 )
2019
39
Delayed Diagnosis of Non-ST Segment Elevation Myocardial Infarction in a Young Patient with Multivessel Disease and Familial Hypercholesterolemia Complicated by Cardiogenic Shock Finally Treated with Intra-Aortic Balloon Pump as a Bridge to Extra Corporeal Membrane Oxygenation. ( 30800482 )
2019
40
A randomized controlled study comparing high-dose insulin to vasopressors or combination therapy in a porcine model of refractory propranolol-induced cardiogenic shock. ( 30806099 )
2019
41
New debate of revascularization strategy of non-infarct-related artery lesions in patients with ST-segment elevation myocardial infarction and cardiogenic shock: decoding the CULPRIT-SHOCK trial, not enough to challenge the current guidelines. ( 30807318 )
2019
42
New debate of revascularization strategy of non-infarct-related artery lesions in patients with ST-segment elevation myocardial infarction and cardiogenic shock: decoding the CULPRIT-SHOCK trial, not enough to challenge the current guidelines. ( 30807360 )
2019
43
Adverse Event Profile Associated with Prolonged Use of CentriMag Ventricular Assist Device for Refractory Cardiogenic Shock. ( 30807379 )
2019
44
Mechanical Circulatory Support in the Cardiac Catheterization Laboratory for Cardiogenic Shock. ( 30808071 )
2019
45
Hemodynamic Support Using Percutaneous Transfemoral Impella 5.0 and Impella RP for Refractory Cardiogenic Shock. ( 30809398 )
2019
46
Update in the Management of Acute Coronary Syndrome Patients with Cardiogenic Shock. ( 30828750 )
2019
47
Coxsackie B2 Virus Infection Causing Multiorgan Failure and Cardiogenic Shock in a 42-Year-Old Man. ( 30833835 )
2019
48
Therapeutic Advances in the Management of Cardiogenic Shock. ( 30839372 )
2019
49
In-Hospital Outcomes After Percutaneous Coronary Intervention for Acute Coronary Syndrome With Cardiogenic Shock (from a Japanese Nationwide Registry [J-PCI Registry]). ( 30846213 )
2019
50
Mechanical Circulatory Support Devices for Cardiogenic Shock: State of the Art. ( 30850001 )
2019

Variations for Cardiogenic Shock

Expression for Cardiogenic Shock

Search GEO for disease gene expression data for Cardiogenic Shock.

Pathways for Cardiogenic Shock

Pathways related to Cardiogenic Shock according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.26 IL6 PLAT
2 10.98 IL6 PLAT
3 10.3 IL6 PLAT

GO Terms for Cardiogenic Shock

Cellular components related to Cardiogenic Shock according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 8.92 ADM IL6 NPPB PLAT

Biological processes related to Cardiogenic Shock according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of signaling receptor activity GO:0010469 9.33 ADM IL6 NPPB
2 response to glucocorticoid GO:0051384 8.96 ADM IL6
3 platelet-derived growth factor receptor signaling pathway GO:0048008 8.62 PIK3C2A PLAT

Molecular functions related to Cardiogenic Shock according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 8.96 ADM NPPB
2 signaling receptor binding GO:0005102 8.8 ADM NPPB PLAT

Sources for Cardiogenic Shock

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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