Cardiomyopathy, Dilated, 1m disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

CMD1M MCID: CRD114 MIFTS: 37	Cardiomyopathy, Dilated, 1m (CMD1M) Categories: Bone diseases, Cardiovascular diseases, Ear diseases, Genetic diseases, Immune diseases, Muscle diseases, Neuronal diseases, Rare diseases
Genes Variations Tissues Related diseases Publications Pathways Symptoms & Phenotypes Expand all tables

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Aliases & Classifications for Cardiomyopathy, Dilated, 1m

MalaCards integrated aliases for Cardiomyopathy, Dilated, 1m:

Name: Cardiomyopathy, Dilated, 1m ⁵⁷ ¹³ ⁷⁰

Dilated Cardiomyopathy 1m ¹² ²⁹ ⁶ ¹⁵

Cmd1m ⁵⁷ ¹² ⁷²

Cardiomyopathy, Dilated, Type 1m ³⁹

Cardiomyopathy, Dilated 1m ⁷²

Characteristics:

HPO:

³¹

cardiomyopathy, dilated, 1m:
Inheritance autosomal dominant inheritance

Classifications:

MalaCards categories:
Global: Genetic diseases Rare diseases
Anatomical: Cardiovascular diseases Immune diseases Neuronal diseases Bone diseases Ear diseases Muscle diseases

See all MalaCards categories (disease lists)

ICD10: ³²

Diseases of the circulatory system

Other forms of heart disease

Cardiomyopathy

Dilated cardiomyopathy

External Ids:

Disease Ontology ¹² DOID:0110449

OMIM® ⁵⁷ 607482

OMIM Phenotypic Series ⁵⁷ PS115200

MeSH ⁴⁴ D002311

ICD10 ³² I42.0

MedGen ⁴¹ C1843808

SNOMED-CT via HPO ⁶⁸ 195021004 263681008 399020009 more

UMLS ⁷⁰ C1843808

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Summaries for Cardiomyopathy, Dilated, 1m

UniProtKB/Swiss-Prot : ⁷² Cardiomyopathy, dilated 1M: A disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.

MalaCards based summary : Cardiomyopathy, Dilated, 1m, also known as dilated cardiomyopathy 1m, is related to myopathy, myofibrillar, 4 and lethal congenital contracture syndrome 4. An important gene associated with Cardiomyopathy, Dilated, 1m is CSRP3 (Cysteine And Glycine Rich Protein 3), and among its related pathways/superpathways are Cardiac conduction and Striated Muscle Contraction. Affiliated tissues include heart, and related phenotypes are dilated cardiomyopathy and endocardial fibroelastosis

Disease Ontology : ¹² A dilated cardiomyopathy that has material basis in mutation in the CSRP3 gene on chromosome 11p15.

More information from OMIM: 607482 PS115200

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Related Diseases for Cardiomyopathy, Dilated, 1m

Diseases in the Rare Cardiomyopathy family:

Cardiomyopathy, Dilated, 1a	Cardiomyopathy, Dilated, 3b
Cardiomyopathy, Dilated, 1b	Cardiomyopathy, Dilated, 1e
Cardiomyopathy, Dilated, 1d	Cardiomyopathy, Dilated, 1g
Cardiomyopathy, Dilated, 1h	Cardiomyopathy, Dilated, 1i
Cardiomyopathy, Dilated, 1j	Cardiomyopathy, Dilated, 1k
Cardiomyopathy, Dilated, 1l	Cardiomyopathy, Dilated, 1m
Cardiomyopathy, Dilated, 1o	Cardiomyopathy, Dilated, 1p
Cardiomyopathy, Dilated, 1q	Cardiomyopathy, Dilated, 1w
Cardiomyopathy, Dilated, 1x	Cardiomyopathy, Dilated, 1z
Cardiomyopathy, Dilated, 2a	Cardiomyopathy, Dilated, 1bb
Cardiomyopathy, Dilated, 1cc	Cardiomyopathy, Dilated, 1dd
Cardiomyopathy, Dilated, 1ee	Cardiomyopathy, Dilated, 1ff
Cardiomyopathy, Dilated, 1r	Cardiomyopathy, Dilated, 1gg
Cardiomyopathy, Dilated, 1u	Cardiomyopathy, Dilated, 1v
Cardiomyopathy, Dilated, 1hh	Cardiomyopathy, Dilated, 2b
Cardiomyopathy, Dilated, 1ii	Cardiomyopathy, Dilated, 1jj
Cardiomyopathy, Dilated, 1kk	Cardiomyopathy, Dilated, 1nn
Cardiomyopathy, Dilated, 2c	Autoimmune Cardiomyopathy
Dilated Cardiomyopathy 1t	Dilated Cardiomyopathy
Lmna-Related Dilated Cardiomyopathy	Cardiomyopathy Due to Anthracyclines

Diseases related to Cardiomyopathy, Dilated, 1m via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 16)

#	Related Disease	Score	Top Affiliating Genes
1	myopathy, myofibrillar, 4	10.2	TCAP CSRP3
2	lethal congenital contracture syndrome 4	10.1	TNNI3 TNNI2
3	cardiomyopathy, dilated, 1p	10.1	TMED2 PNPLA4 CDC42SE1
4	myopathy, myofibrillar, 9, with early respiratory failure	10.1	TCAP CSRP3
5	silent myocardial infarction	10.0	TNNI3 APOA1
6	restrictive cardiomyopathy	10.0	TNNI3 MYL2 CSRP3
7	atrial standstill 1	9.9	TNNI3 MYL2 CSRP3
8	angina pectoris	9.9	TNNI3 APOA1
9	congenital fiber-type disproportion	9.9	TNNI2 MYL2 MYH2
10	cardiomyopathy, familial hypertrophic, 7	9.8	TNNI3 TMED2 PNPLA4 CSRP3 CDC42SE1
11	intrinsic cardiomyopathy	9.8	TNNI3 TCAP MYL2 CSRP3
12	left ventricular noncompaction	9.8	TNNI3 TCAP MYL2 CSRP3
13	intermediate coronary syndrome	9.7	TNNI3 APOA1
14	transverse myelitis	9.7	APOH APOA1
15	pulmonary artery disease	9.7	TNNI3 APOH
16	cardiomyopathy, familial hypertrophic, 1	9.6	TNNI3 TCAP MYL2 MYH2 CSRP3

Graphical network of the top 20 diseases related to Cardiomyopathy, Dilated, 1m:

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Symptoms & Phenotypes for Cardiomyopathy, Dilated, 1m

Human phenotypes related to Cardiomyopathy, Dilated, 1m:

³¹

#	Description	HPO Source Accession
1	dilated cardiomyopathy ³¹	HP:0001644
2	endocardial fibroelastosis ³¹	HP:0001706
3	impaired myocardial contractility ³¹	HP:0006670

Clinical features from OMIM®:

607482 (Updated 20-May-2021)

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Drugs & Therapeutics for Cardiomyopathy, Dilated, 1m

Search Clinical Trials , NIH Clinical Center for Cardiomyopathy, Dilated, 1m

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Genetic Tests for Cardiomyopathy, Dilated, 1m

Genetic tests related to Cardiomyopathy, Dilated, 1m:

#	Genetic test	Affiliating Genes
1	Dilated Cardiomyopathy 1m ²⁹	CSRP3

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Anatomical Context for Cardiomyopathy, Dilated, 1m

MalaCards organs/tissues related to Cardiomyopathy, Dilated, 1m:

⁴⁰

Heart

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Publications for Cardiomyopathy, Dilated, 1m

Articles related to Cardiomyopathy, Dilated, 1m:

#	Title	Authors	PMID	Year
1	Beyond the sarcomere: CSRP3 mutations cause hypertrophic cardiomyopathy. ⁶ ⁵⁷	Geier C...Ozcelik C	18505755	2008
2	Mutations in the muscle LIM protein and alpha-actinin-2 genes in dilated cardiomyopathy and endocardial fibroelastosis. ⁶ ⁵⁷	Mohapatra B...Bowles NE	14567970	2003
3	Mutant Muscle LIM Protein C58G causes cardiomyopathy through protein depletion. ⁶	Ehsan M...Gehmlich K	30048712	2018
4	MLP and CARP are linked to chronic PKCα signalling in dilated cardiomyopathy. ⁶	Lange S...Ehler E	27353086	2016
5	Novel genotype-phenotype associations demonstrated by high-throughput sequencing in patients with hypertrophic cardiomyopathy. ⁶	Lopes LR...Elliott PM	25351510	2015
6	Genetic complexity in hypertrophic cardiomyopathy revealed by high-throughput sequencing. ⁶	Lopes LR...Elliott PM	23396983	2013
7	Genetic diagnosis of hypertrophic cardiomyopathy using mass spectrometry DNA arrays and high resolution melting. ⁶	Santos S...Fernandes AR	21425739	2011
8	Genotype-phenotype relationships involving hypertrophic cardiomyopathy-associated mutations in titin, muscle LIM protein, and telethonin. ⁶	Bos JM...Ackerman MJ	16352453	2006
9	Mutations in the human muscle LIM protein gene in families with hypertrophic cardiomyopathy. ⁶	Geier C...Osterziel KJ	12642359	2003
10	The cardiac mechanical stretch sensor machinery involves a Z disc complex that is defective in a subset of human dilated cardiomyopathy. ⁵⁷	Knoll R...Chien KR	12507422	2002

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Genes for Cardiomyopathy, Dilated, 1m

Genes related to Cardiomyopathy, Dilated, 1m (1 elite genes):

(show all 16)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubMed IDs
1	CSRP3	Cysteine And Glycine Rich Protein 3	Protein Coding	1098.22	Molecular basis known ⁵⁷ Pathogenic ⁶ Genetic Tests ²⁹ Unconfirmed association ⁵⁷ Likely pathogenic ⁶ DISEASES inferred ¹⁵ GeneCards inferred via : Disorders Variants (show sections)	14567970 16352453 21425739
2	CDC42SE1	CDC42 Small Effector 1	Protein Coding	7.61	DISEASES inferred ¹⁵
3	PNPLA4	Patatin Like Phospholipase Domain Containing 4	Protein Coding	7.23	DISEASES inferred ¹⁵
4	TMED2	Transmembrane P24 Trafficking Protein 2	Protein Coding	7.11	DISEASES inferred ¹⁵
5	ATP6V1F	ATPase H+ Transporting V1 Subunit F	Protein Coding	6.14	DISEASES inferred ¹⁵
6	BPHL	Biphenyl Hydrolase Like	Protein Coding	5.93	DISEASES inferred ¹⁵
7	TNNI2	Troponin I2, Fast Skeletal Type	Protein Coding	5.46	DISEASES inferred ¹⁵
8	TNNI3	Troponin I3, Cardiac Type	Protein Coding	5.07	DISEASES inferred ¹⁵
9	TCAP	Titin-Cap	Protein Coding	5.01	DISEASES inferred ¹⁵
10	MYH2	Myosin Heavy Chain 2	Protein Coding	4.76	DISEASES inferred ¹⁵
11	MYL2	Myosin Light Chain 2	Protein Coding	4.41	DISEASES inferred ¹⁵
12	GAP43	Growth Associated Protein 43	Protein Coding	4.36	DISEASES inferred ¹⁵
13	PLP1	Proteolipid Protein 1	Protein Coding	4.34	DISEASES inferred ¹⁵
14	RBM8A	RNA Binding Motif Protein 8A	Protein Coding	4.32	DISEASES inferred ¹⁵
15	APOH	Apolipoprotein H	Protein Coding	4.05	DISEASES inferred ¹⁵
16	APOA1	Apolipoprotein A1	Protein Coding	3.31	DISEASES inferred ¹⁵

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Variations for Cardiomyopathy, Dilated, 1m

ClinVar genetic disease variations for Cardiomyopathy, Dilated, 1m:

⁶ (show top 50) (show all 118)

#	Gene	Name	Type	Significance	ClinVarId	dbSNP ID	Position
1	CSRP3	NM_003476.5(CSRP3):c.206A>G (p.Lys69Arg)	SNV	Pathogenic	8780	rs137852764	GRCh37: 11:19209758-19209758 GRCh38: 11:19188211-19188211
2	CSRP3	NM_003476.5(CSRP3):c.131T>C (p.Leu44Pro)	SNV	Pathogenic	8778	rs104894205	GRCh37: 11:19209833-19209833 GRCh38: 11:19188286-19188286
3	CSRP3	NM_003476.5(CSRP3):c.128del (p.Ala43fs)	Deletion	Likely pathogenic	847161		GRCh37: 11:19209836-19209836 GRCh38: 11:19188289-19188289
4	CSRP3	NM_003476.5(CSRP3):c.449G>A (p.Cys150Tyr)	SNV	Likely pathogenic	219444	rs761507504	GRCh37: 11:19206558-19206558 GRCh38: 11:19185011-19185011
5	CSRP3	NM_003476.5(CSRP3):c.149C>A (p.Ala50Glu)	SNV	Uncertain significance	934985		GRCh37: 11:19209815-19209815 GRCh38: 11:19188268-19188268
6	CSRP3	NM_003476.5(CSRP3):c.168C>G (p.Ile56Met)	SNV	Uncertain significance	944590		GRCh37: 11:19209796-19209796 GRCh38: 11:19188249-19188249
7	CSRP3	NM_003476.5(CSRP3):c.409G>T (p.Gly137Cys)	SNV	Uncertain significance	950593		GRCh37: 11:19207768-19207768 GRCh38: 11:19186221-19186221
8	CSRP3	NM_003476.5(CSRP3):c.93C>G (p.His31Gln)	SNV	Uncertain significance	217825	rs863225265	GRCh37: 11:19213903-19213903 GRCh38: 11:19192356-19192356
9	CSRP3	NM_003476.5(CSRP3):c.265G>T (p.Gly89Cys)	SNV	Uncertain significance	958665		GRCh37: 11:19209699-19209699 GRCh38: 11:19188152-19188152
10	CSRP3	NM_003476.5(CSRP3):c.149C>T (p.Ala50Val)	SNV	Uncertain significance	960236		GRCh37: 11:19209815-19209815 GRCh38: 11:19188268-19188268
11	CSRP3	NM_003476.5(CSRP3):c.285C>A (p.Ser95=)	SNV	Uncertain significance	962276		GRCh37: 11:19207892-19207892 GRCh38: 11:19186345-19186345
12	CSRP3	NM_003476.5(CSRP3):c.311C>T (p.Thr104Ile)	SNV	Uncertain significance	963688		GRCh37: 11:19207866-19207866 GRCh38: 11:19186319-19186319
13	CSRP3	NM_003476.5(CSRP3):c.459T>A (p.Ser153Arg)	SNV	Uncertain significance	963816		GRCh37: 11:19206548-19206548 GRCh38: 11:19185001-19185001
14	CSRP3	NM_003476.5(CSRP3):c.116C>G (p.Ala39Gly)	SNV	Uncertain significance	968411		GRCh37: 11:19209848-19209848 GRCh38: 11:19188301-19188301
15	CSRP3	NM_003476.5(CSRP3):c.562_564CAA[1] (p.Gln189del)	Microsatellite	Uncertain significance	451189	rs1173035411	GRCh37: 11:19204235-19204237 GRCh38: 11:19182688-19182690
16	CSRP3	NM_003476.5(CSRP3):c.151G>T (p.Ala51Ser)	SNV	Uncertain significance	1005786		GRCh37: 11:19209813-19209813 GRCh38: 11:19188266-19188266
17	CSRP3	NM_003476.5(CSRP3):c.377C>G (p.Ser126Ter)	SNV	Uncertain significance	1008253		GRCh37: 11:19207800-19207800 GRCh38: 11:19186253-19186253
18	CSRP3	NM_003476.5(CSRP3):c.49_55del (p.Val17fs)	Deletion	Uncertain significance	1009234		GRCh37: 11:19213941-19213947 GRCh38: 11:19192394-19192400
19	CSRP3	NM_003476.5(CSRP3):c.72del (p.Gln24fs)	Deletion	Uncertain significance	1011003		GRCh37: 11:19213924-19213924 GRCh38: 11:19192377-19192377
20	CSRP3	NM_003476.5(CSRP3):c.111C>A (p.Cys37Ter)	SNV	Uncertain significance	915721		GRCh37: 11:19213885-19213885 GRCh38: 11:19192338-19192338
21	CSRP3	NM_003476.5(CSRP3):c.229G>T (p.Ala77Ser)	SNV	Uncertain significance	201694	rs746207	GRCh37: 11:19209735-19209735 GRCh38: 11:19188188-19188188
22	CSRP3	NM_003476.5(CSRP3):c.143C>T (p.Thr48Ile)	SNV	Uncertain significance	1038977		GRCh37: 11:19209821-19209821 GRCh38: 11:19188274-19188274
23	CSRP3	NM_003476.5(CSRP3):c.265G>A (p.Gly89Ser)	SNV	Uncertain significance	163012	rs367827746	GRCh37: 11:19209699-19209699 GRCh38: 11:19188152-19188152
24	CSRP3	NM_003476.5(CSRP3):c.332C>G (p.Thr111Ser)	SNV	Uncertain significance	1045403		GRCh37: 11:19207845-19207845 GRCh38: 11:19186298-19186298
25	CSRP3	NM_003476.5(CSRP3):c.196T>A (p.Tyr66Asn)	SNV	Uncertain significance	1045551		GRCh37: 11:19209768-19209768 GRCh38: 11:19188221-19188221
26	CSRP3	NM_003476.5(CSRP3):c.300C>G (p.Arg100=)	SNV	Uncertain significance	1047451		GRCh37: 11:19207877-19207877 GRCh38: 11:19186330-19186330
27	CSRP3	NM_003476.5(CSRP3):c.140C>T (p.Thr47Met)	SNV	Uncertain significance	44685	rs397516851	GRCh37: 11:19209824-19209824 GRCh38: 11:19188277-19188277
28	CSRP3	NM_003476.5(CSRP3):c.229G>A (p.Ala77Thr)	SNV	Uncertain significance	1055034		GRCh37: 11:19209735-19209735 GRCh38: 11:19188188-19188188
29	CSRP3	NM_003476.5(CSRP3):c.214G>A (p.Gly72Arg)	SNV	Uncertain significance	1055352		GRCh37: 11:19209750-19209750 GRCh38: 11:19188203-19188203
30	CSRP3	NM_003476.5(CSRP3):c.335C>T (p.Ala112Val)	SNV	Uncertain significance	1058043		GRCh37: 11:19207842-19207842 GRCh38: 11:19186295-19186295
31	CSRP3	NM_003476.5(CSRP3):c.358T>C (p.Cys120Arg)	SNV	Uncertain significance	1062510		GRCh37: 11:19207819-19207819 GRCh38: 11:19186272-19186272
32	CSRP3	NM_003476.5(CSRP3):c.10T>C (p.Trp4Arg)	SNV	Uncertain significance	8776	rs45550635	GRCh37: 11:19213986-19213986 GRCh38: 11:19192439-19192439
33	CSRP3	NM_003476.5(CSRP3):c.298C>T (p.Arg100Cys)	SNV	Uncertain significance	851709		GRCh37: 11:19207879-19207879 GRCh38: 11:19186332-19186332
34	CSRP3	NM_003476.5(CSRP3):c.174C>T (p.Cys58=)	SNV	Uncertain significance	381101	rs1057520959	GRCh37: 11:19209790-19209790 GRCh38: 11:19188243-19188243
35	CSRP3	NM_003476.5(CSRP3):c.455_456AG[1] (p.Leu154fs)	Microsatellite	Uncertain significance	855956		GRCh37: 11:19206549-19206550 GRCh38: 11:19185002-19185003
36	CSRP3	NM_003476.5(CSRP3):c.286C>T (p.Pro96Ser)	SNV	Uncertain significance	858415		GRCh37: 11:19207891-19207891 GRCh38: 11:19186344-19186344
37	CSRP3	NM_003476.5(CSRP3):c.17G>A (p.Gly6Glu)	SNV	Uncertain significance	859311		GRCh37: 11:19213979-19213979 GRCh38: 11:19192432-19192432
38	CSRP3	NM_003476.5(CSRP3):c.228C>T (p.Gly76=)	SNV	Uncertain significance	861575		GRCh37: 11:19209736-19209736 GRCh38: 11:19188189-19188189
39	CSRP3	NM_003476.5(CSRP3):c.284C>T (p.Ser95Phe)	SNV	Uncertain significance	863545		GRCh37: 11:19207893-19207893 GRCh38: 11:19186346-19186346
40	CSRP3	NM_003476.5(CSRP3):c.436C>T (p.Arg146Cys)	SNV	Uncertain significance	426380	rs376198883	GRCh37: 11:19206571-19206571 GRCh38: 11:19185024-19185024
41	CSRP3	NM_003476.5(CSRP3):c.461T>G (p.Leu154Arg)	SNV	Uncertain significance	476575	rs1554967431	GRCh37: 11:19206546-19206546 GRCh38: 11:19184999-19184999
42	CSRP3	NM_003476.5(CSRP3):c.544G>C (p.Gly182Arg)	SNV	Uncertain significance	201695	rs111868331	GRCh37: 11:19204258-19204258 GRCh38: 11:19182711-19182711
43	CSRP3	NM_003476.5(CSRP3):c.230C>G (p.Ala77Gly)	SNV	Uncertain significance	476570	rs772138289	GRCh37: 11:19209734-19209734 GRCh38: 11:19188187-19188187
44	CSRP3	NM_003476.5(CSRP3):c.136A>C (p.Ser46Arg)	SNV	Uncertain significance	8781	rs137852765	GRCh37: 11:19209828-19209828 GRCh38: 11:19188281-19188281
45	CSRP3	NM_003476.5(CSRP3):c.524dup (p.Asn175fs)	Duplication	Uncertain significance	476576	rs1554967256	GRCh37: 11:19204277-19204278 GRCh38: 11:19182730-19182731
46	CSRP3	NM_003476.5(CSRP3):c.26A>C (p.Lys9Thr)	SNV	Uncertain significance	476572	rs1352827887	GRCh37: 11:19213970-19213970 GRCh38: 11:19192423-19192423
47	CSRP3	NM_003476.5(CSRP3):c.22G>A (p.Ala8Thr)	SNV	Uncertain significance	404174	rs45531937	GRCh37: 11:19213974-19213974 GRCh38: 11:19192427-19192427
48	CSRP3	NC_000011.10:g.(?_19184942)_(19188314_?)del	Deletion	Uncertain significance	831881		GRCh37: 11:19206489-19209861 GRCh38:
49	CSRP3	NM_003476.5(CSRP3):c.415-1G>A	SNV	Uncertain significance	834445		GRCh37: 11:19206593-19206593 GRCh38: 11:19185046-19185046
50	CSRP3	NM_003476.5(CSRP3):c.127G>T (p.Ala43Ser)	SNV	Uncertain significance	835944		GRCh37: 11:19209837-19209837 GRCh38: 11:19188290-19188290

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Expression for Cardiomyopathy, Dilated, 1m

Search GEO for disease gene expression data for Cardiomyopathy, Dilated, 1m.

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Pathways for Cardiomyopathy, Dilated, 1m

Pathways related to Cardiomyopathy, Dilated, 1m according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Cardiac conduction ⁶⁵ Show member pathways Classical Kir channels ⁶⁵ Ion homeostasis ⁶⁵ Ion transport by P-type ATPases ⁶⁵ Muscle contraction ⁶⁵ Phase 1 - inactivation of fast Na+ channels ⁶⁵ Phase 3 - rapid repolarisation ⁶⁵ Phase 4 - resting membrane potential ⁶⁵ Physiological factors ⁶⁵ Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK) ⁶⁵ Tandem pore domain halothane-inhibited K+ channel (THIK) ⁶⁵ Tandem pore domain potassium channels ⁶⁵ TWIK related potassium channel (TREK) ⁶⁵ TWIK-related alkaline pH activated K+ channel (TALK) ⁶⁵ TWIK-related spinal cord K+ channel (TRESK) ⁶⁵ TWIK-releated acid-sensitive K+ channel (TASK) ⁶⁵	12.29	TNNI3 TNNI2 TCAP MYL2
2	Striated Muscle Contraction ¹ ⁶⁵	10.78	TNNI3 TNNI2 TCAP MYL2
3	N-cadherin signaling events ¹	10.67	MYL2 GAP43
4	Glial Cell Differentiation ¹	9.86	PLP1 GAP43

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GO Terms for Cardiomyopathy, Dilated, 1m

Cellular components related to Cardiomyopathy, Dilated, 1m according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	high-density lipoprotein particle	GO:0034364	9.4	APOH APOA1
2	very-low-density lipoprotein particle	GO:0034361	9.37	APOH APOA1
3	chylomicron	GO:0042627	9.32	APOH APOA1
4	troponin complex	GO:0005861	9.26	TNNI3 TNNI2
5	cardiac myofibril	GO:0097512	9.16	TNNI3 MYL2
6	myofibril	GO:0030016	9.13	TNNI3 MYL2 MYH2
7	sarcomere	GO:0030017	9.02	TNNI3 TCAP MYL2 MYH2 CSRP3

Biological processes related to Cardiomyopathy, Dilated, 1m according to GeneCards Suite gene sharing:

(show all 14)

#	Name	GO ID	Score	Top Affiliating Genes
1	muscle contraction	GO:0006936	9.61	TNNI3 TNNI2 MYH2
2	sarcomere organization	GO:0045214	9.54	TCAP CSRP3
3	ventricular cardiac muscle tissue morphogenesis	GO:0055010	9.52	TNNI3 MYL2
4	regulation of the force of heart contraction	GO:0002026	9.51	MYL2 CSRP3
5	regulation of muscle contraction	GO:0006937	9.49	TNNI3 TNNI2
6	glial cell differentiation	GO:0010001	9.48	PLP1 GAP43
7	heart contraction	GO:0060047	9.46	TNNI3 MYL2
8	skeletal muscle contraction	GO:0003009	9.43	TNNI3 TNNI2 TCAP
9	cardiac muscle hypertrophy	GO:0003300	9.4	TCAP CSRP3
10	positive regulation of lipoprotein lipase activity	GO:0051006	9.37	APOH APOA1
11	cardiac myofibril assembly	GO:0055003	9.33	TCAP MYL2 CSRP3
12	detection of muscle stretch	GO:0035995	9.32	TCAP CSRP3
13	cardiac muscle contraction	GO:0060048	9.26	TNNI3 TNNI2 TCAP CSRP3
14	muscle filament sliding	GO:0030049	9.02	TNNI3 TNNI2 TCAP MYL2 MYH2

Molecular functions related to Cardiomyopathy, Dilated, 1m according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	actin binding	GO:0003779	9.46	TNNI3 TNNI2 MYH2 CSRP3
2	troponin T binding	GO:0031014	8.96	TNNI3 TNNI2
3	structural constituent of muscle	GO:0008307	8.8	TCAP MYL2 CSRP3

Sources

Sources for Cardiomyopathy, Dilated, 1m

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ EFO

¹⁸ ExPASy

¹⁹ FMA

²⁰ GARD

²¹ GeneAnalytics

²² GeneCards

²³ GeneGo (Thomson Reuters)

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Cardiomyopathy, Dilated, 1m (CMD1M)

Aliases & Classifications for Cardiomyopathy, Dilated, 1m

MalaCards integrated aliases for Cardiomyopathy, Dilated, 1m:

Characteristics:

HPO:

Classifications:

External Ids:

Summaries for Cardiomyopathy, Dilated, 1m

Related Diseases for Cardiomyopathy, Dilated, 1m

Diseases in the Rare Cardiomyopathy family:

Diseases related to Cardiomyopathy, Dilated, 1m via text searches within MalaCards or GeneCards Suite gene sharing:

Graphical network of the top 20 diseases related to Cardiomyopathy, Dilated, 1m:

Symptoms & Phenotypes for Cardiomyopathy, Dilated, 1m

Human phenotypes related to Cardiomyopathy, Dilated, 1m:

Clinical features from OMIM®:

Drugs & Therapeutics for Cardiomyopathy, Dilated, 1m

Genetic Tests for Cardiomyopathy, Dilated, 1m

Genetic tests related to Cardiomyopathy, Dilated, 1m:

Anatomical Context for Cardiomyopathy, Dilated, 1m

MalaCards organs/tissues related to Cardiomyopathy, Dilated, 1m:

Publications for Cardiomyopathy, Dilated, 1m

Articles related to Cardiomyopathy, Dilated, 1m:

Genes for Cardiomyopathy, Dilated, 1m

Genes related to Cardiomyopathy, Dilated, 1m (1 elite genes):

Variations for Cardiomyopathy, Dilated, 1m

ClinVar genetic disease variations for Cardiomyopathy, Dilated, 1m:

Expression for Cardiomyopathy, Dilated, 1m

Pathways for Cardiomyopathy, Dilated, 1m

Pathways related to Cardiomyopathy, Dilated, 1m according to GeneCards Suite gene sharing:

GO Terms for Cardiomyopathy, Dilated, 1m

Cellular components related to Cardiomyopathy, Dilated, 1m according to GeneCards Suite gene sharing:

Biological processes related to Cardiomyopathy, Dilated, 1m according to GeneCards Suite gene sharing:

Molecular functions related to Cardiomyopathy, Dilated, 1m according to GeneCards Suite gene sharing:

Sources for Cardiomyopathy, Dilated, 1m