Cardiovascular Organ Benign Neoplasm disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

Sources

Aliases & Classifications for Cardiovascular Organ Benign Neoplasm

MalaCards integrated aliases for Cardiovascular Organ Benign Neoplasm:

Name: Cardiovascular Organ Benign Neoplasm ¹² ¹⁵

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Cardiovascular diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:0060091

Sources

Summaries for Cardiovascular Organ Benign Neoplasm

Disease Ontology : ¹² An organ system benign neoplasm disease located in the blood, heart, blood vessels or the lymphatic system.

MalaCards based summary : Cardiovascular Organ Benign Neoplasm is related to human venous malformation and proliferative fasciitis. An important gene associated with Cardiovascular Organ Benign Neoplasm is GLMN (Glomulin, FKBP Associated Protein). Affiliated tissues include heart, skin and liver, and related phenotypes are cardiovascular system and growth/size/body region

Sources

Related Diseases for Cardiovascular Organ Benign Neoplasm

Diseases related to Cardiovascular Organ Benign Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 78)

#	Related Disease	Score	Top Affiliating Genes
1	human venous malformation	10.3	GLMN TEK
2	proliferative fasciitis	10.2	MB STAT6
3	glomangioma	10.2	GLMN TEK TRPV1
4	diverticulitis of colon	10.2	KIT TRPV1
5	ceruminoma	10.2	KIT SLC2A1
6	hyperhidrosis, gustatory	10.2	ATP2A2 KANTR
7	bone remodeling disease	10.2	FGF23 LEMD3 TRPV1
8	trigeminal nerve disease	10.2	TAC1 TRPV1
9	capillary hemangioma	10.1	SLC2A1 TEK
10	ovarian melanoma	10.1	CALD1 KIT
11	sphenoid sinusitis	10.1	GJB6 KANTR
12	gallbladder leiomyoma	10.1	CD34 KIT
13	lung leiomyosarcoma	10.1	CD34 KIT
14	glomangiomatosis	10.1	ATP2A2 GJB6 GLMN LEMD3
15	dental abscess	10.1	KANTR KIT
16	bronchial disease	10.1	STAT6 TAC1 TRPV1
17	liver leiomyoma	10.1	CD34 KIT
18	glomangiosarcoma	10.1	KANTR TAC1
19	extracutaneous mastocytoma	10.1	CD34 KIT
20	small intestine leiomyosarcoma	10.1	CD34 KIT
21	small intestinal sarcoma	10.1	CD34 KIT
22	gallbladder sarcoma	10.1	CD34 KIT
23	prostate leiomyosarcoma	10.1	CD34 KIT
24	adenosarcoma	10.1	KIT MB
25	posterior myocardial infarction	10.1	KANTR MB
26	plexiform schwannoma	10.1	CD34 KIT
27	meninges sarcoma	10.1	CD34 MB
28	subendocardial myocardial infarction	10.1	KANTR MB
29	anismus	10.1	KANTR TAC1
30	burning mouth syndrome	10.1	TAC1 TRPV1
31	sciatic neuropathy	10.1	KANTR TRPV1
32	breast angiosarcoma	10.1	CD34 KIT
33	mixed liposarcoma	10.1	CD34 MB
34	senile angioma	10.1	CD34 KIT
35	visual agnosia	10.1	KANTR MB
36	adult fibrosarcoma	10.1	CD34 MB
37	deep angioma	10.1	CD34 SLC2A1
38	arteries, anomalies of	10.1	KANTR MB TRPV1
39	mononeuropathy	10.1	TAC1 TRPV1
40	spindle cell liposarcoma	10.0	CD34 KIT
41	leiomyoma cutis	10.0	CALD1 TAC1 TRPV1
42	mechanical ectropion	10.0	CD34 KANTR
43	nervous system benign neoplasm	10.0	CD34 KIT TRPV1
44	malignant mesenchymoma	10.0	CALD1 KIT MB
45	connective tissue cancer	10.0	CD34 KIT TRPV1
46	breast myofibroblastoma	10.0	CALD1 CD34
47	intravascular fasciitis	10.0	CALD1 CD34
48	oculogyric crisis	10.0	KANTR SLC2A1
49	thyroid crisis	10.0	KANTR MB
50	glomangiomyoma	10.0	CALD1 CD34

Graphical network of the top 20 diseases related to Cardiovascular Organ Benign Neoplasm:

Sources

Symptoms & Phenotypes for Cardiovascular Organ Benign Neoplasm

MGI Mouse Phenotypes related to Cardiovascular Organ Benign Neoplasm:

⁴⁶

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	cardiovascular system	MP:0005385	10.11	ATP2A2 FGF23 GJB6 GLMN KIT LEMD3
2	growth/size/body region	MP:0005378	9.96	ATP2A2 FGF23 GLMN KIT MB PDPN
3	homeostasis/metabolism	MP:0005376	9.93	ATP2A2 CD34 FGF23 GJB6 GLMN KIT
4	embryo	MP:0005380	9.87	ATP2A2 GLMN KIT LEMD3 MB SLC2A1
5	integument	MP:0010771	9.61	ATP2A2 CD34 FGF23 GJB6 KIT PDPN
6	renal/urinary system	MP:0005367	9.1	ATP2A2 FGF23 KIT STAT6 TAC1 TRPV1

Sources

Drugs & Therapeutics for Cardiovascular Organ Benign Neoplasm

Search Clinical Trials , NIH Clinical Center for Cardiovascular Organ Benign Neoplasm

Sources

Genetic Tests for Cardiovascular Organ Benign Neoplasm

Sources

Anatomical Context for Cardiovascular Organ Benign Neoplasm

MalaCards organs/tissues related to Cardiovascular Organ Benign Neoplasm:

⁴¹

Heart, Skin, Liver, Bone, Colon, Breast, Small Intestine

The Foundational Model of Anatomy Ontology organs/tissues related to Cardiovascular Organ Benign Neoplasm:

¹⁹

The Blood

Sources

Publications for Cardiovascular Organ Benign Neoplasm

Sources

Genes for Cardiovascular Organ Benign Neoplasm

Genes related to Cardiovascular Organ Benign Neoplasm (0 elite genes):

(show all 17)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	GLMN	Glomulin, FKBP Associated Protein	Protein Coding	18.03	DISEASES inferred ¹⁵
2	TRPV1	Transient Receptor Potential Cation Channel Subfamily V Member 1	Protein Coding	17.6	DISEASES inferred ¹⁵ ¹⁵
3	ATP2A2	ATPase Sarcoplasmic/Endoplasmic Reticulum Ca2+ Transporting 2	Protein Coding	15.31	DISEASES inferred ¹⁵
4	LEMD3	LEM Domain Containing 3	Protein Coding	15.22	DISEASES inferred ¹⁵
5	TEK	TEK Receptor Tyrosine Kinase	Protein Coding	14.73	DISEASES inferred ¹⁵
6	GJB6	Gap Junction Protein Beta 6	Protein Coding	14.21	DISEASES inferred ¹⁵
7	STAT6	Signal Transducer And Activator Of Transcription 6	Protein Coding	13.73	DISEASES inferred ¹⁵
8	KIT	KIT Proto-Oncogene Receptor Tyrosine Kinase	Protein Coding	13.64	DISEASES inferred ¹⁵
9	MB	Myoglobin	Protein Coding	13.45	DISEASES inferred ¹⁵
10	FGF23	Fibroblast Growth Factor 23	Protein Coding	13.41	DISEASES inferred ¹⁵
11	SLC2A1	Solute Carrier Family 2 Member 1	Protein Coding	13.3	DISEASES inferred ¹⁵
12	TAC1	Tachykinin Precursor 1	Protein Coding	13.1	DISEASES inferred ¹⁵
13	ZBTB8OS	Zinc Finger And BTB Domain Containing 8 Opposite Strand	Protein Coding	5.83	DISEASES inferred ¹⁵
14	CALD1	Caldesmon 1	Protein Coding	5.15	DISEASES inferred ¹⁵
15	CD34	CD34 Molecule	Protein Coding	4.84	DISEASES inferred ¹⁵
16	PDPN	Podoplanin	Protein Coding	3.37	DISEASES inferred ¹⁵
17	KANTR	KDM5C Adjacent Transcript	RNA Gene	2.96	DISEASES inferred ¹⁵

Sources

Variations for Cardiovascular Organ Benign Neoplasm

Sources

Expression for Cardiovascular Organ Benign Neoplasm

Search GEO for disease gene expression data for Cardiovascular Organ Benign Neoplasm.

Sources

Pathways for Cardiovascular Organ Benign Neoplasm

Sources

GO Terms for Cardiovascular Organ Benign Neoplasm

Cellular components related to Cardiovascular Organ Benign Neoplasm according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	integral component of plasma membrane	GO:0005887	9.7	ATP2A2 CD34 KIT PDPN SLC2A1 TEK
2	membrane raft	GO:0045121	9.26	PDPN SLC2A1 STAT6 TEK
3	apical plasma membrane	GO:0016324	9.02	CD34 GJB6 PDPN SLC2A1 TEK

Biological processes related to Cardiovascular Organ Benign Neoplasm according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	response to pain	GO:0048265	8.96	TAC1 TRPV1
2	endothelial cell proliferation	GO:0001935	8.62	CD34 TEK

Molecular functions related to Cardiovascular Organ Benign Neoplasm according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	Ras guanyl-nucleotide exchange factor activity	GO:0005088	8.8	FGF23 KIT TEK

Sources

Sources for Cardiovascular Organ Benign Neoplasm

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ ExPASy

¹⁸ FDA Approved Drugs

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HGMD

³¹ HMDB

³² HPO

³³ ICD10

³⁴ ICD10 via Orphanet

³⁵ ICD9CM

³⁶ IUPHAR

³⁷ KEGG

³⁸ LifeMap

³⁹ LncRNADisease

⁴⁰ LOVD

⁴¹ MalaCards

⁴² MedGen

⁴³ MedlinePlus

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NIH Rare Diseases

⁵⁴ NINDS

⁵⁵ Novoseek

⁵⁶ Novus Biologicals

⁵⁷ OMIM

⁵⁸ OMIM via Orphanet

⁵⁹ Orphanet

⁶⁰ PathCards

⁶¹ PharmGKB

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ SNOMED-CT via Orphanet

⁷¹ TGDB

⁷² Tocris

⁷³ UMLS

⁷⁴ UMLS via Orphanet

⁷⁵ UniProtKB/Swiss-Prot

⁷⁶ Wikipedia