Cardiovascular Organ Benign Neoplasm disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Cardiovascular Organ Benign Neoplasm

MalaCards integrated aliases for Cardiovascular Organ Benign Neoplasm:

Name: Cardiovascular Organ Benign Neoplasm ¹² ¹⁵

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Cardiovascular diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:0060091

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Summaries for Cardiovascular Organ Benign Neoplasm

Disease Ontology : ¹² An organ system benign neoplasm disease located in the blood, heart, blood vessels or the lymphatic system.

MalaCards based summary : Cardiovascular Organ Benign Neoplasm is related to human venous malformation and familial glomangioma. An important gene associated with Cardiovascular Organ Benign Neoplasm is GLMN (Glomulin, FKBP Associated Protein), and among its related pathways/superpathways are Glucose / Energy Metabolism and HIF-1 signaling pathway. Affiliated tissues include the blood and heart, and related phenotypes are cardiovascular system and cellular

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Related Diseases for Cardiovascular Organ Benign Neoplasm

Diseases related to Cardiovascular Organ Benign Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 76)

#	Related Disease	Score	Top Affiliating Genes
1	human venous malformation	10.9	GLMN TEK
2	familial glomangioma	10.8	FGF2 GLMN
3	histiocytoid hemangioma	10.7	GLMN HBA1
4	mongolian spot	10.7	ENO2 FLNA
5	breast rhabdomyosarcoma	10.7	ENO2 MB
6	choriocarcinoma of ovary	10.7	ENO2 TEK
7	brain compression	10.6	FGF2 GJB6
8	lichen nitidus	10.6	ATP2A2 FLNA
9	kidney rhabdoid cancer	10.6	ENO2 MB
10	senile entropion	10.5	FLNA KANTR
11	hyperhidrosis, gustatory	10.5	ATP2A2 KANTR
12	glomangiomatosis	10.5	ATP2A2 GJB6 GLMN LEMD3
13	meninges sarcoma	10.5	CD34 MB
14	glomangiosarcoma	10.4	KANTR TAC1
15	leech infestation	10.4	FLNA KANTR
16	sarcomatoid squamous cell skin carcinoma	10.4	CD34 MB
17	chronic myocardial ischemia	10.4	FGF2 TEK
18	lung meningioma	10.4	CD34 ENO2
19	capillary hemangioma	10.4	HBA1 SLC2A1 TEK
20	neuroma	10.4	ENO2 FGF2 TRPV1
21	sclerosing liposarcoma	10.4	CD34 MB
22	ovary sarcoma	10.4	CD34 HBA1
23	melorheostosis	10.4	FGF2 LEMD3
24	ovarian angiosarcoma	10.4	CD34 HBA1
25	pediatric angiosarcoma	10.4	CD34 HBA1
26	thyroid angiosarcoma	10.4	CD34 HBA1
27	neurogenic arthropathy	10.3	CD34 HBA1
28	sphenoid sinusitis	10.3	GJB6 KANTR
29	spleen angiosarcoma	10.3	CD34 HBA1
30	bone epithelioid hemangioma	10.3	CD34 HBA1
31	gastric leiomyosarcoma	10.3	CD34 ENO2
32	thyroid sarcoma	10.3	CD34 HBA1
33	deep angioma	10.3	CD34 SLC2A1
34	pericardium cancer	10.3	ENO2 HBA1 MB
35	glomeruloid hemangioma	10.3	CD34 HBA1
36	pericardial mesothelioma	10.3	ENO2 HBA1 MB
37	mechanical ectropion	10.3	CD34 KANTR
38	hemangioma of liver	10.3	CD34 HBA1
39	intramuscular hemangioma	10.3	CD34 SLC2A1 TEK
40	arteries, anomalies of	10.3	KANTR MB TRPV1
41	extraosseous osteosarcoma	10.2	CD34 HBA1
42	anismus	10.2	KANTR TAC1
43	spleen cancer	10.2	CD34 HBA1
44	spindle cell synovial sarcoma	10.2	CD34 MB SLC2A1
45	breast angiosarcoma	10.2	CD34 HBA1
46	plexiform schwannoma	10.2	CD34 ENO2
47	conventional angiosarcoma	10.2	CD34 HBA1
48	breast myofibroblastoma	10.1	CALD1 CD34
49	deep leiomyoma	10.1	CALD1 CD34
50	glomangiomyoma	10.1	CALD1 CD34

Graphical network of the top 20 diseases related to Cardiovascular Organ Benign Neoplasm:

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Symptoms & Phenotypes for Cardiovascular Organ Benign Neoplasm

MGI Mouse Phenotypes related to Cardiovascular Organ Benign Neoplasm:

⁴⁶

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	cardiovascular system	MP:0005385	9.93	LEMD3 MB PDPN TAC1 ATP2A2 TEK
2	cellular	MP:0005384	9.65	LEMD3 MB SLC2A1 ATP2A2 CD34 TRPV1
3	homeostasis/metabolism	MP:0005376	9.4	MB PDPN SLC2A1 ATP2A2 TEK CD34

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Drugs & Therapeutics for Cardiovascular Organ Benign Neoplasm

Search Clinical Trials , NIH Clinical Center for Cardiovascular Organ Benign Neoplasm

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Genetic Tests for Cardiovascular Organ Benign Neoplasm

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Anatomical Context for Cardiovascular Organ Benign Neoplasm

The Foundational Model of Anatomy Ontology organs/tissues related to Cardiovascular Organ Benign Neoplasm:

¹⁹

The Blood

MalaCards organs/tissues related to Cardiovascular Organ Benign Neoplasm:

⁴¹

Heart

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Publications for Cardiovascular Organ Benign Neoplasm

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Genes for Cardiovascular Organ Benign Neoplasm

Genes related to Cardiovascular Organ Benign Neoplasm (0 elite genes):

(show all 19)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	GLMN	Glomulin, FKBP Associated Protein	Protein Coding	18.18	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
2	TRPV1	Transient Receptor Potential Cation Channel Subfamily V Member 1	Protein Coding	17.87	DISEASES inferred ¹⁵ ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
3	ATP2A2	ATPase Sarcoplasmic/Endoplasmic Reticulum Ca2+ Transporting 2	Protein Coding	15.43	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
4	LEMD3	LEM Domain Containing 3	Protein Coding	15.32	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
5	TEK	TEK Receptor Tyrosine Kinase	Protein Coding	14.9	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
6	GJB6	Gap Junction Protein Beta 6	Protein Coding	14.33	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
7	FLNA	Filamin A	Protein Coding	13.96	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
8	MB	Myoglobin	Protein Coding	13.56	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
9	FGF23	Fibroblast Growth Factor 23	Protein Coding	13.52	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
10	SLC2A1	Solute Carrier Family 2 Member 1	Protein Coding	13.48	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
11	TAC1	Tachykinin Precursor 1	Protein Coding	13.24	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
12	ENO2	Enolase 2	Protein Coding	13.13	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
13	FGF2	Fibroblast Growth Factor 2	Protein Coding	13.1	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
14	HBA1	Hemoglobin Subunit Alpha 1	Protein Coding	13.05	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
15	ZBTB8OS	Zinc Finger And BTB Domain Containing 8 Opposite Strand	Protein Coding	5.98	DISEASES inferred ¹⁵
16	CD34	CD34 Molecule	Protein Coding	4.74	DISEASES inferred ¹⁵
17	CALD1	Caldesmon 1	Protein Coding	4.38	DISEASES inferred ¹⁵
18	PDPN	Podoplanin	Protein Coding	3.6	DISEASES inferred ¹⁵
19	KANTR	KDM5C Adjacent Transcript	RNA Gene	3.05	DISEASES inferred ¹⁵

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Variations for Cardiovascular Organ Benign Neoplasm

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Expression for Cardiovascular Organ Benign Neoplasm

Search GEO for disease gene expression data for Cardiovascular Organ Benign Neoplasm.

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Pathways for Cardiovascular Organ Benign Neoplasm

Pathways related to Cardiovascular Organ Benign Neoplasm according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Glucose / Energy Metabolism ⁴	12.05	ATP2A2 ENO2 MB SLC2A1
2	HIF-1 signaling pathway ³⁷	11.33	ENO2 SLC2A1 TEK
3	Angiogenesis (CST) ⁴	11.08	FGF2 PDPN TEK
4	Effects of Nitric Oxide ¹	9.53	HBA1 MB

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GO Terms for Cardiovascular Organ Benign Neoplasm

Cellular components related to Cardiovascular Organ Benign Neoplasm according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	apical plasma membrane	GO:0016324	9.02	CD34 GJB6 PDPN SLC2A1 TEK

Biological processes related to Cardiovascular Organ Benign Neoplasm according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	response to pain	GO:0048265	9.32	TAC1 TRPV1
2	endothelial cell proliferation	GO:0001935	9.26	CD34 TEK
3	oxygen transport	GO:0015671	9.16	HBA1 MB
4	wound healing, spreading of cells	GO:0044319	8.96	FLNA PDPN
5	stem cell proliferation	GO:0072089	8.62	CD34 FGF2

Molecular functions related to Cardiovascular Organ Benign Neoplasm according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	Ras guanyl-nucleotide exchange factor activity	GO:0005088	9.13	FGF2 FGF23 TEK
2	oxygen carrier activity	GO:0005344	8.62	HBA1 MB

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