MCID: CRT011
MIFTS: 27

Carotenemia

Categories: Metabolic diseases, Skin diseases

Aliases & Classifications for Carotenemia

MalaCards integrated aliases for Carotenemia:

Name: Carotenemia 12 76 15
Hypercarotinemia 12 73

Classifications:



External Ids:

Disease Ontology 12 DOID:9969
ICD10 33 E67.1
ICD9CM 35 278.3
NCIt 50 C26963
SNOMED-CT 68 35487009
UMLS 73 C0154271

Summaries for Carotenemia

MalaCards based summary : Carotenemia, also known as hypercarotinemia, is related to amenorrhea and pernicious anemia. An important gene associated with Carotenemia is APOA4 (Apolipoprotein A4), and among its related pathways/superpathways are Lipoprotein metabolism and Metabolism of fat-soluble vitamins. Affiliated tissues include skin, brain and testes, and related phenotype is Decreased free cholesterol.

Wikipedia : 76 An excess of dietary carotenoids may cause a marked orange discoloration of the outermost skin layer.... more...

Related Diseases for Carotenemia

Diseases related to Carotenemia via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 13)
# Related Disease Score Top Affiliating Genes
1 amenorrhea 10.1
2 pernicious anemia 10.0
3 celiac disease 1 10.0
4 macular degeneration, age-related, 1 10.0
5 hypothyroidism 10.0
6 food allergy 10.0
7 biliary dyskinesia 10.0
8 demyelinating polyneuropathy 9.9 APOA4 TTR
9 amyloidosis aa 9.8 LPA TTR
10 coronary heart disease 1 9.8 APOA4 LPA
11 amyloidosis, familial visceral 9.8 LPA TTR
12 hypercholesterolemia, familial 9.8 APOA4 LPA
13 chronic kidney failure 9.6 LPA TTR

Graphical network of the top 20 diseases related to Carotenemia:



Diseases related to Carotenemia

Symptoms & Phenotypes for Carotenemia

GenomeRNAi Phenotypes related to Carotenemia according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased free cholesterol GR00340-A-2 8.62 APOA4 LPA

Drugs & Therapeutics for Carotenemia

Search Clinical Trials , NIH Clinical Center for Carotenemia

Genetic Tests for Carotenemia

Anatomical Context for Carotenemia

MalaCards organs/tissues related to Carotenemia:

41
Skin, Brain, Testes, Kidney, Heart

Publications for Carotenemia

Articles related to Carotenemia:

(show all 36)
# Title Authors Year
1
Orangechrome Due to Carotenemia Presenting as Trichrome Vitiligo. ( 29927313 )
2018
2
Orangeness-Peeling Back the Myths Behind Carotenemia. ( 28903145 )
2017
3
Carotenemia and Age-Related Macular Degeneration: Seeing Is Believing. ( 27319957 )
2016
4
Hypercarotinemia after bariatric surgery. ( 26611152 )
2016
5
Carotenemia and hepatomegaly in an atopic child on an exclusion diet for a food allergy. ( 26490299 )
2015
6
Generalized yellow discoloration of the skin. The diagnosis: carotenemia. ( 24897145 )
2014
7
A case of carotenemia associated with ingestion of nutrient supplements. ( 16556283 )
2006
8
Carotenemia in infancy and its association with prevalent feeding practices. ( 17156001 )
2006
9
Carotenemia associated with green bean ingestion. ( 15575851 )
2004
10
Carotenemia. ( 12839253 )
2003
11
Carotenoderma in metabolic carotenemia. ( 9567535 )
1997
12
Metabolic carotenemia and carotenoderma in a child. ( 7747541 )
1995
13
Hyper-beta-carotenemia unrelated to diet: a case of brain tumor. ( 7657475 )
1995
14
A correlation between carotenemia and biliary dyskinesia. ( 8340533 )
1993
15
IgA antigliadin antibodies, cellobiose/mannitol sugar test, and carotenemia in the diagnosis of and screening for celiac disease. ( 1900142 )
1991
16
Benign carotenemia in children. ( 21253272 )
1989
17
Carotenemia. ( 3318296 )
1987
18
Carotenemia. ( 3604848 )
1987
19
Dieting and carotenemia--sometimes a cause and effect. ( 6233252 )
1984
20
Amenorrhea associated with carotenemia. ( 6876328 )
1983
21
Carotenemia. ( 6618745 )
1983
22
Amenorrhea associated with carotenemia. ( 6823046 )
1983
23
Carotenemia. A review. ( 7449242 )
1981
24
Carotenemia-a caveat. ( 6108315 )
1980
25
Carotenemia vs jaundice. ( 1036531 )
1976
26
Transport of beta-carotene in serum of individuals with carotenemia. ( 4371997 )
1974
27
Carotenemia in mentally retarded children. I. Incidence and etiology. ( 4707231 )
1973
28
Carotenemia associated with papaya ingestion. ( 5696561 )
1968
29
Carotenemia. A case report. ( 6074816 )
1967
30
CAROTENEMIA AND CAROTENODERMA. ( 14115107 )
1964
31
Lycopenemia: a variant of carotenemia. ( 14437033 )
1960
32
Observations on carotenemia. ( 13509531 )
1958
33
The carotenemia of hypothyroidism. ( 13011698 )
1952
34
Carotenemia; a case report. ( 15397622 )
1949
35
Carotenemia in a patient with pernicious anemia. ( 20240697 )
1947
36
Carotenemia. ( 20240682 )
1947

Variations for Carotenemia

Expression for Carotenemia

Search GEO for disease gene expression data for Carotenemia.

Pathways for Carotenemia

GO Terms for Carotenemia

Cellular components related to Carotenemia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 collagen-containing extracellular matrix GO:0062023 9.16 APCS APOA4
2 blood microparticle GO:0072562 8.96 APCS APOA4
3 extracellular region GO:0005576 8.92 APCS APOA4 LPA TTR

Biological processes related to Carotenemia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 lipid transport GO:0006869 9.16 APOA4 LPA
2 retinoid metabolic process GO:0001523 8.96 APOA4 TTR
3 cellular protein metabolic process GO:0044267 8.8 APCS APOA4 TTR

Molecular functions related to Carotenemia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 8.8 APCS APOA4 TTR

Sources for Carotenemia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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