MCID: CRT008
MIFTS: 33

Carotid Artery Dissection

Categories: Cardiovascular diseases, Neuronal diseases

Aliases & Classifications for Carotid Artery Dissection

MalaCards integrated aliases for Carotid Artery Dissection:

Name: Carotid Artery Dissection 12 74 6 15 71
Dissection of Carotid Artery 12

Classifications:



External Ids:

Disease Ontology 12 DOID:9348
ICD9CM 34 443.21
NCIt 49 C125662
SNOMED-CT 67 720626009
ICD10 32 I77.71
UMLS 71 C0338585

Summaries for Carotid Artery Dissection

MalaCards based summary : Carotid Artery Dissection, also known as dissection of carotid artery, is related to carotid artery occlusion and fibromuscular dysplasia. An important gene associated with Carotid Artery Dissection is LDLR (Low Density Lipoprotein Receptor). The drugs Heparin and Enoxaparin have been mentioned in the context of this disorder. Affiliated tissues include brain, tongue and testes.

Wikipedia : 74 Carotid artery dissection is a separation of the layers of the artery wall supplying oxygen-bearing... more...

Related Diseases for Carotid Artery Dissection

Diseases related to Carotid Artery Dissection via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 164)
# Related Disease Score Top Affiliating Genes
1 carotid artery occlusion 30.8 MYLK LDLR
2 fibromuscular dysplasia 30.7 PHACTR1 MYLK
3 aneurysm 30.5 MYLK COL3A1
4 aortic dissection 30.4 LDLR COL3A1
5 moyamoya disease 1 29.6 PHACTR1 MYLK
6 horner's syndrome 10.8
7 headache 10.7
8 familial cervical artery dissection 10.7
9 transient cerebral ischemia 10.5
10 aphasia 10.5
11 cranial nerve palsy 10.4
12 stroke, ischemic 10.4
13 ptosis 10.4
14 hemiplegia 10.4
15 amaurosis fugax 10.4
16 migraine with or without aura 1 10.4
17 asplenia, isolated congenital 10.4
18 branch retinal artery occlusion 10.4
19 retinal artery occlusion 10.4
20 eagle syndrome 10.4
21 cluster headache 10.3
22 anisocoria 10.3
23 yemenite deaf-blind hypopigmentation syndrome 10.3
24 cerebral artery occlusion 10.3
25 central retinal artery occlusion 10.3
26 dysphagia 10.3
27 retinal ischemia 10.3
28 carotid stenosis 10.3
29 facial paralysis 10.2
30 intracranial aneurysm 10.2
31 vascular disease 10.2
32 middle cerebral artery infarction 10.2
33 connective tissue disease 10.2
34 vasculitis 10.2
35 head injury 10.2
36 specific language disorder 10.2
37 takayasu arteritis 10.2
38 ocular motor apraxia 10.2
39 anhidrosis 10.2
40 multiple cranial nerve palsy 10.2
41 optic nerve disease 10.2
42 neuropathy 10.2
43 whiplash 10.2
44 polycystic kidney disease 10.1
45 migraine with aura 10.1
46 pertussis 10.1
47 ehlers-danlos syndrome 10.1
48 intracranial embolism 10.1
49 kidney disease 10.1
50 47,xyy 10.1

Graphical network of the top 20 diseases related to Carotid Artery Dissection:



Diseases related to Carotid Artery Dissection

Symptoms & Phenotypes for Carotid Artery Dissection

Drugs & Therapeutics for Carotid Artery Dissection

Drugs for Carotid Artery Dissection (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 27)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Heparin Approved, Investigational Phase 3 9005-49-6 46507594 772
2
Enoxaparin Approved Phase 3 9005-49-6 772
3
Warfarin Approved Phase 3 81-81-2 6691 54678486
4
Clopidogrel Approved Phase 3 113665-84-2, 120202-66-6 60606
5
Dalteparin Approved Phase 3 9005-49-6
6
Tinzaparin Approved Phase 3 9041-08-1, 9005-49-6 25244225
7
Aspirin Approved, Vet_approved Phase 3 50-78-2 2244
8
Dipyridamole Approved Phase 3 58-32-2 3108
9 Fibrinolytic Agents Phase 3
10 Phosphodiesterase Inhibitors Phase 3
11 Purinergic P2Y Receptor Antagonists Phase 3
12 Analgesics, Non-Narcotic Phase 3
13 Anticoagulants Phase 3
14 Heparin, Low-Molecular-Weight Phase 3
15 Neurotransmitter Agents Phase 3
16 Vasodilator Agents Phase 3
17 Platelet Aggregation Inhibitors Phase 3
18 Analgesics Phase 3
19 Coagulants Phase 3
20 Anti-Inflammatory Agents Phase 3
21 Cyclooxygenase Inhibitors Phase 3
22 Calcium, Dietary Phase 3
23 Antirheumatic Agents Phase 3
24 calcium heparin Phase 3
25 Antipyretics Phase 3
26 Anti-Inflammatory Agents, Non-Steroidal Phase 3
27
Calcium Nutraceutical Phase 3 7440-70-2 271

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Cervical Artery Dissection in Stroke Study Completed NCT00238667 Phase 3 Antiplatelet (Aspirin, Dipyridamole, clopidogrel);Anticoagulant (Unfractionated Heparin, LMW Heparin, Warfarin)
2 A Randomized Trial of Carotid Artery Stenting With and Without Cerebral Protection Completed NCT00177346
3 Automated Pupillometry for the Diagnosis of Horner's Syndrome in Acute Stroke Patients Due to Carotid Artery Dissection Recruiting NCT02978079

Search NIH Clinical Center for Carotid Artery Dissection

Genetic Tests for Carotid Artery Dissection

Anatomical Context for Carotid Artery Dissection

MalaCards organs/tissues related to Carotid Artery Dissection:

40
Brain, Tongue, Testes, Kidney, Bone, Pituitary, Cortex

Publications for Carotid Artery Dissection

Articles related to Carotid Artery Dissection:

(show top 50) (show all 1128)
# Title Authors PMID Year
1
Clinical case of successful treatment of internal carotid artery dissection during aneurysm embolization in acute period of subarachnoid hemorrhage. 61
32547674 2020
2
Endovascular Treatment of Spontaneous Internal Carotid Artery Dissection with Proximal Embolic Protection Device. 61
31904520 2020
3
Two Cases Treated by Different Strategies for Common Carotid Artery Dissection with Thrombosis Due to a Type A Aortic Dissection. 61
32549110 2020
4
Carotid Artery Dissection: A Rare Presenting Manifestation of Takayasu Arteritis. 61
32558679 2020
5
Endovascular reconstruction of extracranial traumatic internal carotid artery dissections: a systematic review. 61
30903316 2020
6
Bilateral carotid artery dissection in a SARS-CoV-2 infected patient: causality or coincidence? 61
32533323 2020
7
Endovascular recanalization for symptomatic subacute and chronically occluded internal carotid artery: feasibility, safety, a modified radiographic classification system, and clinical outcomes. 61
32494963 2020
8
Retinal and Optic Nerve Ischemia due to an Internal Carotid Artery Dissection: The "Cup of Wine" Sign. 61
32544904 2020
9
Stylo-carotid syndrome causing bilateral cervical carotid artery dissection requiring endovascular intervention. 61
32474259 2020
10
Treat the vessel, save the heart: a rare case of spontaneous sensitive carotid artery dissection. 61
32238794 2020
11
An Updated Systematic Review and Meta-Analysis of Results of Transcervical Carotid Artery Stenting with Flow Reversal. 61
32422272 2020
12
Surgical Thromboendarterectomy for Free-Floating Thrombus Associated with Cervical Carotid Artery Dissection: A Case Report. 61
32439523 2020
13
Spontaneous Carotid Artery Dissection Presenting as Trigeminal Neuralgia in the Emergency Department. 61
32426687 2020
14
Predictors of Cervical Vertebral and Carotid Artery Dissection During Blunt Trauma: Experience From a Level 1 Trauma Center. 61
32028007 2020
15
Early Multicenter Experience With the Neuroform Atlas Stent: Feasibility, Safety, and Efficacy. 61
32453816 2020
16
Facial twitching: calcium or concussion conundrum? Hypocalcaemia in a young American football player masking an internal carotid artery dissection. 61
32350051 2020
17
Horner Syndrome Due To Internal Carotid Artery Dissection With Normal Vascular Imaging: A Radiological Conundrum. 61
32355049 2020
18
Forensic and Clinical Issues in a Case of Motorcycle Blunt Trauma and Bilateral Carotid Artery Dissection. 61
31655108 2020
19
Carotid artery dissection associated with Purtscher-like retinopathy. 61
31712014 2020
20
Differential expression of PHACTR1 in atheromatous versus normal carotid artery tissue. 61
31980275 2020
21
Eagle Syndrome and Internal Carotid Artery Dissection: Description of Five Cases Treated in Two Italian Institutions and Review of the Literature. 61
32205242 2020
22
A Case of Isolated Unilateral Glossopharyngeal Nerve Palsy. 61
31511240 2020
23
Endovascular Treatment of Internal Carotid Artery Dissection Presenting with Acute Ischemic Stroke. 61
31883782 2020
24
Carotid Artery Dissection Induced Acute Tongue Swelling in a Cocaine User. 61
32214522 2020
25
Spontaneous extracranial arterial dissections in a case of patient with osteogenesis imperfecta. 61
32138586 2020
26
A unique temporary collateral pathway between carotid-vertebrobasilar arteries in a carotid dissection patient. 61
32183730 2020
27
Internal Carotid Artery Dissection Presenting as Partial Horner's Syndrome and Vertigo. 61
32060548 2020
28
Dissection of Arch Branches Alone: An Indication for Aggressive Arch Management in Type A Dissection? 61
31404544 2020
29
Identical Horner Syndrome in Homozygotic Twins Caused by Non-Traumatic Internal Carotid Artery Dissection. 61
32076445 2020
30
Cerebral collaterals and stroke in patients with isolated carotid artery dissections. 61
31937504 2020
31
Tandem occlusion involving accessory middle cerebral artery in acute ischaemic stroke: management strategies. 61
32041762 2020
32
Emergency carotid artery revascularization using Casper-RX stent: A single-center experience. 61
32046548 2020
33
Letter to the Editor Regarding "A Staged Therapy for Internal Carotid Artery Dissection Caused by Vascular Eagle Syndrome". 61
32059277 2020
34
Delayed bilateral internal carotid artery dissection following motor vehicle accident: Time to make its screening a part of trauma protocol? 61
32096863 2020
35
Flow-diverter reconstruction of an intracranial internal carotid artery dissection during thrombectomy for acute ischaemic stroke. 61
31969403 2020
36
Stenting for Acute Carotid Artery Dissection. 61
31795908 2020
37
[Internal carotid artery dissection which mimicry trigeminal neuralgia and cluster headache]. 61
32030703 2020
38
Sonographic features of carotid artery dissection due to extension of aortic dissection: a case report. 61
31792729 2019
39
Pipeline Embolization Device for Treatment of Craniocervical Internal Carotid Artery Dissections: Report of 3 Cases. 61
31491581 2019
40
Bilateral Traumatic Internal Carotid Artery Dissection after CrossFit Training. 61
31344463 2019
41
Isolated hypoglossal nerve palsy from internal carotid artery dissection related to PKD-1 gene mutation. 61
31703639 2019
42
Internal Carotid Artery Dissection Presenting With Dysgeusia, Horner Syndrome, and Hypesthesia of the Fifth Cranial Nerve: A Case Report. 61
31711825 2019
43
A Case of Juvenile Stroke due to Carotid Artery Dissection from an Elongated Styloid Process-Revisiting Conservative Management. 61
31383620 2019
44
Discovery of a Novel Mutation in the REN Gene in Patient With Chronic Progressive Kidney Disease of Unknown Etiology Presenting With Acute Spontaneous Carotid Artery Dissection. 61
31371142 2019
45
Emergent Rescue Extracranial-Intracranial Bypass for Acute Carotid Stent Thrombosis Report. 61
31207372 2019
46
A Staged Therapy for Internal Carotid Artery Dissection Caused by Vascular Eagle Syndrome. 61
31154103 2019
47
Left Subclavian-Bilateral External Carotid Artery Bypass for Symptomatic Carotid Artery Dissection Secondary to Open Repair of Type A Aortic Dissection. 61
31636751 2019
48
Genetic analysis of ring finger protein 213 (RNF213) c.14576G>A polymorphism in patients with vertebral artery dissection: a comparative study with moyamoya disease. 61
31064275 2019
49
Carotid artery dissection secondary to carotid artery trauma caused by giant C1 transverse process. 61
28089538 2019
50
Unusual complication of carotid artery stenting as the result of a proximal emboli protection device (the Mo.Ma): Iatrogenic common carotid artery dissection. 61
31584432 2019

Variations for Carotid Artery Dissection

ClinVar genetic disease variations for Carotid Artery Dissection:

6 ‎‎ ‎‎
# Gene Name Type Significance ClinVarId dbSNP ID GRCh37 Pos GRCh38 Pos
1 LDLR NM_000527.5(LDLR):c.682G>A (p.Glu228Lys)SNV Pathogenic/Likely pathogenic 3691 rs121908029 19:11216264-11216264 19:11105588-11105588
2 MYLK NM_053025.4(MYLK):c.2149G>A (p.Asp717Asn)SNV Uncertain significance 519975 rs150936840 3:123426842-123426842 3:123707995-123707995

Expression for Carotid Artery Dissection

Search GEO for disease gene expression data for Carotid Artery Dissection.

Pathways for Carotid Artery Dissection

GO Terms for Carotid Artery Dissection

Biological processes related to Carotid Artery Dissection according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 aorta smooth muscle tissue morphogenesis GO:0060414 8.62 MYLK COL3A1

Sources for Carotid Artery Dissection

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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