Carotid Artery Thrombosis disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Carotid Artery Thrombosis

MalaCards integrated aliases for Carotid Artery Thrombosis:

Name: Carotid Artery Thrombosis ¹¹ ⁵³ ⁴³ ¹⁴ ¹⁶ ⁷¹

Classifications:

MalaCards categories:
Anatomical: Cardiovascular diseases Neuronal diseases Blood diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹¹ DOID:3410

MeSH ⁴³ D002341

SNOMED-CT ⁶⁸ 195181000

EFO ¹⁶ EFO_1000853

UMLS ⁷¹ C0007274

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Summaries for Carotid Artery Thrombosis

MalaCards based summary: Carotid Artery Thrombosis is related to exanthem and carotid stenosis. An important gene associated with Carotid Artery Thrombosis is F3 (Coagulation Factor III, Tissue Factor), and among its related pathways/superpathways are Signal Transduction and Response to elevated platelet cytosolic Ca2+. Affiliated tissues include brain, endothelial and neutrophil, and related phenotypes are homeostasis/metabolism and nervous system

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Related Diseases for Carotid Artery Thrombosis

Diseases related to Carotid Artery Thrombosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 252)

#	Related Disease	Score	Top Affiliating Genes
1	exanthem	30.2	IFNG F3 CSF2
2	carotid stenosis	30.2	VWF SELP NOS3 IFNG
3	severe covid-19	30.0	VWF IFNG F3 CSF2
4	mastoiditis	30.0	SERPINC1 F3
5	buerger disease	30.0	SERPINC1 NOS3
6	cerebrovascular disease	29.8	SELP PLG PLAT P2RY12
7	thrombocytosis	29.7	VWF SERPINC1 SELP F3 CSF2
8	carotid artery occlusion	29.7	SELP PLG PLAT GP6 F11
9	middle cerebral artery infarction	29.7	PLG PLAT F3
10	acute promyelocytic leukemia	29.7	SELP PLAT IFNG F3 CSF2
11	aspergillosis	29.6	PLG IFNG CSF2
12	hellp syndrome	29.4	VWF SERPINE1 SERPINC1 PLAT F3
13	antithrombin iii deficiency	29.4	SERPINC1 PLG F3 F10
14	factor viii deficiency	29.4	VWF SERPINC1 F3 F11 F10
15	thrombophilia due to thrombin defect	29.3	VWF SERPINE1 SERPINC1 SELP PLAT F3
16	transient cerebral ischemia	29.2	VWF SERPINC1 PLG PLAT P2RY12 F3
17	antiphospholipid syndrome	28.9	VWF SERPINE1 SERPINC1 SELP PLAT GP1BA
18	carotid artery disease	28.7	VWF SELP PLG PLAT P2RY12 ITGA2B
19	vascular disease	28.7	VWF SERPINE1 SERPINC1 SELP PLAT NOS3
20	pulmonary embolism	28.7	VWF SERPINE1 SERPINC1 PLAT GP6 GP1BA
21	thrombophlebitis	28.6	VWF SERPINE1 SERPINC1 SELP PLG PLAT
22	thrombophilia	28.5	VWF SERPINE1 SERPINC1 SELP PLAT NOS3
23	disseminated intravascular coagulation	28.2	VWF SERPINE1 SERPINC1 PLG PLAT F3
24	thrombosis	27.7	VWF SERPINE1 SERPINC1 SELP PLG PLAT
25	stroke, ischemic	27.7	VWF SERPINE1 SERPINC1 SELP PLG PLAT
26	thrombocytopenia	26.8	VWF SERPINE1 SERPINC1 SELP PLAT P2RY12
27	epidural abscess	10.3	IFNG F3
28	candida glabrata	10.3	IFNG CSF2
29	intracranial arteriosclerosis	10.3	SERPINE1 SELP
30	mucormycosis	10.2
31	heparin-induced thrombocytopenia	10.2	ITGA2B F3
32	femoral neuropathy	10.2	PLAT F3
33	peyronie's disease	10.2	SERPINE1 NOS3
34	splenic disease	10.2	IFNG F3 CSF2
35	aspirin allergy	10.2	P2RY12 ITGA2B
36	brachydactyly, type d	10.2	VWF F3 F10
37	eisenmenger syndrome	10.2	VWF PLAT
38	trimethoprim allergy	10.2	IFNG GP1BA
39	hemophilia a	10.2	VWF F3 F10
40	fetal and neonatal alloimmune thrombocytopenia	10.2	ITGA2B GP1BA
41	hemophagocytic lymphohistiocytosis	10.2	IFNG F3 CSF2
42	autosomal dominant macrothrombocytopenia	10.1	ITGA2B GP1BA
43	central serous chorioretinopathy	10.1	SERPINE1 PLAT
44	achenbach syndrome	10.1	SERPINC1 F3
45	scott syndrome	10.1	ITGA2B GP6 F10
46	high molecular weight kininogen deficiency	10.1	F3 F11
47	childhood acute megakaryoblastic leukemia	10.1	ITGA2B GP1BA
48	autoimmune disease of blood	10.1	VWF ITGA2B F3
49	giant hemangioma	10.1	SERPINC1 F3
50	preeclampsia/eclampsia 1	10.1	SERPINC1 NOS3

Graphical network of the top 20 diseases related to Carotid Artery Thrombosis:

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Symptoms & Phenotypes for Carotid Artery Thrombosis

GenomeRNAi Phenotypes related to Carotid Artery Thrombosis according to GeneCards Suite gene sharing:

²⁵

#	Description	GenomeRNAi Source Accession	Score	Top Affiliating Genes
1	no effect	GR00402-S-1	10.13	CSF2 F10 F11 F2R F3 GP1BA
2	no effect	GR00402-S-2	10.13	CSF2 F10 F2R F3 GP1BA GP6

MGI Mouse Phenotypes related to Carotid Artery Thrombosis:

⁴⁵ (show all 18)

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	homeostasis/metabolism	MP:0005376	10.45	CSF2 F10 F11 F2R F3 GP1BA
2	nervous system	MP:0003631	10.35	CSF2 F11 F2R F3 IFNG ITGA2B
3	growth/size/body region	MP:0005378	10.32	CSF2 F10 F11 F2R F3 IFNG
4	cardiovascular system	MP:0005385	10.3	CSF2 F10 F11 F2R F3 IFNG
5	cellular	MP:0005384	10.29	CSF2 F11 F2R F3 GP1BA IFNG
6	immune system	MP:0005387	10.28	CSF2 F11 F2R F3 GP6 IFNG
7	renal/urinary system	MP:0005367	10.21	CSF2 F10 F2R IFNG NOS3 PLG
8	liver/biliary system	MP:0005370	10.14	F11 F2R IFNG NOS3 PLG SELP
9	muscle	MP:0005369	10.09	F11 F3 IFNG NOS3 PLAT SERPINC1
10	reproductive system	MP:0005389	10.07	CSF2 F10 F2R GP6 IFNG ITGA2B
11	respiratory system	MP:0005388	10.06	CSF2 F11 F3 IFNG NOS3 PLAT
12	hematopoietic system	MP:0005397	10.06	CSF2 F11 F2R F3 GP1BA GP6
13	neoplasm	MP:0002006	10.05	CSF2 F2R F3 IFNG PLG SERPINE1
14	digestive/alimentary	MP:0005381	10.04	F2R IFNG ITGA2B NOS3 PLAT PLG
15	skeleton	MP:0005390	9.97	CSF2 F2R GP6 IFNG ITGA2B NOS3
16	vision/eye	MP:0005391	9.91	F2R F3 GP6 IFNG NOS3 PLAT
17	mortality/aging	MP:0010768	9.83	CSF2 F10 F11 F2R F3 GP6
18	integument	MP:0010771	9.28	CSF2 F3 GP6 IFNG ITGA2B PLAT

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Drugs & Therapeutics for Carotid Artery Thrombosis

Interventional clinical trials:

#	Name	Status	NCT ID	Phase	Drugs
1	Randomized Clinical Trial of Polyester vs. Polyurethane Patch for Carotid Endarterectomy. Long-term Results	Completed	NCT02341196

Search NIH Clinical Center for Carotid Artery Thrombosis

Cochrane evidence based reviews: carotid artery thrombosis

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Genetic Tests for Carotid Artery Thrombosis

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Anatomical Context for Carotid Artery Thrombosis

Organs/tissues related to Carotid Artery Thrombosis:

MalaCards : Brain, Endothelial, Neutrophil, Myeloid, Cortex, Eye, Kidney

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Publications for Carotid Artery Thrombosis

Articles related to Carotid Artery Thrombosis:

(show top 50) (show all 456)

#	Title	Authors	PMID	Year
1	Antithrombotic activity of a monoclonal antibody inducing the substrate form of plasminogen activator inhibitor type 1 in rat models of venous and arterial thrombosis. ⁵³ ⁶²	Berry CN...O'Connor SE	9776340	1998
2	Inhibition of endothelial cell expression of plasminogen activator inhibitor type-1 by gemfibrozil. ⁵³ ⁶²	Fujii S...Sobel BE	7509512	1993
3	An unusual case of carotidynia preceding recurrent ischemic stroke with carotid thrombosis in a patient with systemic lupus erythematosus. ⁶²	Jeong W...Kim JG	36289010	2022
4	Apolipoprotein A-I, elevated in trauma patients, inhibits platelet activation and decreases clot strength. ⁶²	Jones WL...Branchford B	35659185	2022
5	Bifunctional fusion protein targeting both FXIIa and FXIa displays potent anticoagulation effects. ⁶²	Jiang S...Li Q	36208658	2022
6	Exclusively Posterior Circulation Stroke Caused by Internal Carotid Artery Thrombosis. ⁶²	Ding Y...Niu J	36395504	2022
7	Neutrophil Recruitment in Arterial Thrombus and Characteristics of Stroke Patients with Neutrophil-Rich Thrombus. ⁶²	Cha MJ...Heo JH	36303310	2022
8	Study on the antithrombotic effect and physiological mechanism of okanin. ⁶²	Liu Y...Sha A	35785699	2022
9	Petrous Carotid Artery Thrombosis in an Immunocompromised Patient Presenting With Mastoiditis, A Case Report. ⁶²	Doyle EJ...Samy RN	36154465	2022
10	Common carotid artery thrombosis and malignant middle cerebral artery infarction following ovarian hyperstimulation syndrome: A case report. ⁶²	Xu YT...Guo ZR	36159413	2022
11	Effective components and mechanism analysis of anti-platelet aggregation effect of Justicia procumbens L. ⁶²	Liu B...Wu HZ	35589019	2022
12	Panax Notoginseng Saponins Combined with Dual Antiplatelet Drugs Potentiates Anti-Thrombotic Effect with Alleviated Gastric Injury in A Carotid Artery Thrombosis Rat Model. ⁶²	Wu Y...Shi D	35716522	2022
13	CT-001 is a rapid clearing factor VIIa with enhanced clearance and hemostatic activity for the treatment of acute bleeding in non-hemophilia settings. ⁶²	Sim DS...Hermiston TW	35640516	2022
14	Engineered platelets-based drug delivery platform for targeted thrombolysis. ⁶²	Wang S...Liu M	35847517	2022
15	Establishment of a Modified and Standardized Ferric Chloride-Induced Rat Carotid Artery Thrombosis Model. ⁶²	Lin X...Zhuge Q	35309441	2022
16	XJ-8, a natural compound isolated from Sanguis draxonis, inhibits platelet function and thrombosis by targeting MAP3K3. ⁶²	Zhu Z...Tu P	34780114	2022
17	Endothelial Dysfunction in SARS-CoV-2 Infection. ⁶²	Nappi F...Avtaar Singh SS	35327455	2022
18	Thrombolytic and anticoagulant effects of a recombinant staphylokinase-hirudin fusion protein. ⁶²	Ren K...Wu C	34688099	2021
19	Oxidized Phospholipids Promote NETosis and Arterial Thrombosis in LNK(SH2B3) Deficiency. ⁶²	Dou H...Tall AR	34846914	2021
20	Anterior Cavernous and Internal Carotid Artery Thrombosis - A Rare Complication of Rhino-orbito-cerebral Mucormycosis. ⁶²	Juneja A...Dubey M	34979719	2021
21	WPK5, a Novel Kunitz-Type Peptide from the Leech Whitmania pigra Inhibiting Factor XIa, and Its Loop-Replaced Mutant to Improve Potency. ⁶²	Zheng YZ...Kong Y	34944561	2021
22	A Nano-Based P1Cminimum Probe to Monitor Thrombosis in Grafts and Improve Cardiac Function After Coronary Artery Bypass Grafting Surgery. ⁶²	Wu Q...Pan C	34706795	2021
23	Symptomatic Carotid Artery Thrombosis in a Patient Recently Recovered From a COVID-19 Infection. ⁶²	Bakirli I...Bakirov I	34659924	2021
24	Left Carotid Artery Thrombosis Due to Thromboangiitis Obliterans. ⁶²	Bourgeau ME...Prahlow JA	33346979	2021
25	Mitochondrial reactive oxygen species scavenging attenuates thrombus formation in a murine model of sickle cell disease. ⁶²	Annarapu GK...Shiva S	33724688	2021
26	Preparation and Properties of Thrombus-Targeted Urokinase/Multi-Walled Carbon Nanotubes (MWCNTs)-Chitosan (CS)-RGD Drug Delivery System. ⁶²	Zhang R...Song YM	34688316	2021
27	Diagnostic Utility of Polymerase Chain Reaction for Paraffin-embedded Sinus Specimens for Rhinocerebral Mucormycosis Complicated by Internal Carotid Artery Thrombosis and Cerebral Infarction. ⁶²	Maeda Y...Kitagawa K	33678746	2021
28	COVID-19-associated ischaemic stroke due to underlying carotid artery thrombosis in a healthy young woman. ⁶²	Lau K...Guerges M	34344659	2021
29	RNAi targeting heparin cofactor II promotes hemostasis in hemophilia A. ⁶²	Lin WY...Tang L	33996250	2021
30	Improved efficacy/safety profile of factor XIa inhibitor BMS-724296 versus factor Xa inhibitor apixaban and thrombin inhibitor dabigatran in cynomolgus monkeys. ⁶²	Wong PC...Quan ML	34095733	2021
31	Wasp sting - Causing a fatal menace. ⁶²	Karri M...Kannan KT	34189358	2021
32	Sanguinarine Attenuates Collagen-Induced Platelet Activation and Thrombus Formation. ⁶²	Shu D...Ming ZY	33919019	2021
33	Delayed stroke after hospitalization for coronavirus disease 2019 pneumonia from common and internal carotid artery thrombosis. ⁶²	Hosseini M...Ucuzian AA	33200108	2021
34	NADPH Oxidases Are Required for Full Platelet Activation In Vitro and Thrombosis In Vivo but Dispensable for Plasma Coagulation and Hemostasis. ⁶²	Vara D...Pula G	33267663	2021
35	QiShenYiQi Inhibits Tissue Plasminogen Activator-Induced Brain Edema and Hemorrhage after Ischemic Stroke in Mice. ⁶²	Ye Y...Han JY	35095486	2021
36	Skull base osteomyelitis with secondary cavernous sinus thrombosis: a rare presentation of an animate foreign body in the ear. ⁶²	Alex A...Lepcha A	33431445	2021
37	[Carotid endarterectomy in patients with internal carotid artery thrombosis in the acutest period of ischemic stroke with COVID-19]. ⁶²	Kazantsev AN...Linets YP	34874651	2021
38	Rare presentations of COVID-19: PRES-like leukoencephalopathy and carotid thrombosis. ⁶²	Doo FX...Belani P	32707411	2021
39	A rare infective cause of stroke in an immunocompetent child. ⁶²	Gupta J...Gulati S	32855000	2021
40	Ref-1 protects against FeCl3-induced thrombosis and tissue factor expression via the GSK3β-NF-κB pathway. ⁶²	Lee I...Kim CS	33361538	2021
41	Case Report: Internal Carotid Artery Thrombosis: A Rare Complication After Fibrin Glue Injection for Cavernous Sinus Hemostasis. ⁶²	Andrade-Barazarte H...Hernesniemi J	34796197	2021
42	Acute ischemic stroke complicating common carotid artery thrombosis during a severe COVID-19 infection. ⁶²	Viguier A...Bonneville F	32389423	2020
43	Durable Response to Pazopanib in Recurrent Metastatic Carotid Body Paraganglioma. ⁶²	Alshamsan B...Atallah JP	33173489	2020
44	Selective Hand Motor Cortex Lesions Masquerading as "Pseudoperipheral Nerve Palsy". ⁶²	Shelley BP...Devadas AK	33623273	2020
45	Internal carotid artery thrombosis in COVID 19. ⁶²	Alvarez Moreno Y...Escober Torres J	33402757	2020
46	Increased dipeptidyl peptidase-4 accelerates chronic stress-related thrombosis in a mouse carotid artery model. ⁶²	Jin X...Cheng XW	32205561	2020
47	Targeting Myeloid-Specific Integrin α9β1 Improves Short- and Long-Term Stroke Outcomes in Murine Models With Preexisting Comorbidities by Limiting Thrombosis and Inflammation. ⁶²	Dhanesha N...Chauhan AK	32195632	2020
48	Ischaemic Stroke Caused by a Gunshot Wound to the Chest. ⁶²	Helan M...Suk P	32881990	2020
49	Linagliptin Regulates the Mitochondrial Respiratory Reserve to Alter Platelet Activation and Arterial Thrombosis. ⁶²	Li Y...Wu J	33328991	2020
50	Antiplatelet Activity of Tussilagone via Inhibition of the GPVI Downstream Signaling Pathway in Platelets. ⁶²	Zhou J...Wang YH	32850895	2020

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Genes for Carotid Artery Thrombosis

Genes related to Carotid Artery Thrombosis (0 elite genes):

(show all 17)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubMed IDs
1	F3	Coagulation Factor III, Tissue Factor	Protein Coding	20.89	DISEASES inferred ¹⁴ Novoseek inferred ⁵³ GeneCards inferred via : Publications (show sections)	9776340
2	F10	Coagulation Factor X	Protein Coding	14.9	DISEASES inferred ¹⁴ GeneCards inferred via : Publications (show sections)
3	NOS3	Nitric Oxide Synthase 3	Protein Coding	11.86	DISEASES inferred ¹⁴ GeneCards inferred via : Publications (show sections)
4	SERPINE1	Serpin Family E Member 1	Protein Coding	9.79	DISEASES inferred ¹⁴ Novoseek inferred ⁵³	7509512
5	CSF2	Colony Stimulating Factor 2	Protein Coding	7.83	GeneCards inferred via : Publications (show sections)
6	IFNG	Interferon Gamma	Protein Coding	7.83	GeneCards inferred via : Publications (show sections)
7	SELP	Selectin P	Protein Coding	6.74	DISEASES inferred ¹⁴
8	ITGA2B	Integrin Subunit Alpha 2b	Protein Coding	6.57	DISEASES inferred ¹⁴
9	GP6	Glycoprotein VI Platelet	Protein Coding	6.45	DISEASES inferred ¹⁴
10	VWF	Von Willebrand Factor	Protein Coding	6.38	DISEASES inferred ¹⁴
11	P2RY12	Purinergic Receptor P2Y12	Protein Coding	6.04	DISEASES inferred ¹⁴
12	PLAT	Plasminogen Activator, Tissue Type	Protein Coding	5.97	DISEASES inferred ¹⁴
13	GP1BA	Glycoprotein Ib Platelet Subunit Alpha	Protein Coding	5.96	DISEASES inferred ¹⁴
14	F11	Coagulation Factor XI	Protein Coding	5.96	DISEASES inferred ¹⁴
15	SERPINC1	Serpin Family C Member 1	Protein Coding	5.96	DISEASES inferred ¹⁴
16	PLG	Plasminogen	Protein Coding	5.92	DISEASES inferred ¹⁴
17	F2R	Coagulation Factor II Thrombin Receptor	Protein Coding	5.74	DISEASES inferred ¹⁴

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Variations for Carotid Artery Thrombosis

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Expression for Carotid Artery Thrombosis

Search GEO for disease gene expression data for Carotid Artery Thrombosis.

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Pathways for Carotid Artery Thrombosis

Pathways related to Carotid Artery Thrombosis according to GeneCards Suite gene sharing:

(show all 16)

#	Super pathways	Score	Top Affiliating Genes
1	Signal Transduction ⁶⁶	13.43	CSF2 F2R F3 ITGA2B NOS3 P2RY12
2	Response to elevated platelet cytosolic Ca2+ ⁶⁶ Show member pathways Disinhibition of SNARE formation ⁶⁶ Hemostasis ⁶⁶ Platelet activation, signaling and aggregation ⁶⁶ Platelet degranulation ⁶⁶	12.56	VWF SERPINE1 SERPINC1 SELP PLG PLAT
3	Complement cascade ⁶⁶ Show member pathways Activation of C3 and C5 ⁶⁶ Classical Complement Pathway ⁶⁴ Complement Pathway ⁶⁴ Complement system ⁷⁴ Complement system in neuronal development and plasticity ⁷⁴ Lectin Induced Complement Pathway ⁶⁴ Regulation of Complement cascade ⁶⁶	12.43	SELP PLG ITGA2B IFNG F10
4	Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) ⁶⁶ Show member pathways Blood clotting cascade ⁷⁴ Blood Coagulation Signaling Pathways ⁶⁵ Common Pathway of Fibrin Clot Formation ⁶⁶ Complement and coagulation cascades ⁷⁴ Defective F8 binding to von Willebrand factor ⁶⁶ Defective F8 cleavage by thrombin ⁶⁶ Defective F8 sulfation at Y1699 ⁶⁶ Defective F9 activation ⁶⁶ Defective F9 secretion ⁶⁶ Defective factor IX causes hemophilia B ⁶⁶ Defective factor VIII causes hemophilia A ⁶⁶ Defective factor XII causes hereditary angioedema ⁶⁶ Defective gamma-carboxylation of F9 ⁶⁶ Diseases of hemostasis ⁶⁶ Extrinsic Pathway of Fibrin Clot Formation ⁶⁶ Extrinsic Prothrombin Activation Pathway ⁶⁴ Formation of Fibrin Clot (Clotting Cascade) ⁶⁶ Intrinsic Pathway of Fibrin Clot Formation ⁶⁶ Thrombin/protease-activated receptor (PAR) pathway ⁶¹	12.16	VWF SERPINE1 SERPINC1 PLG PLAT GP6
5	Adhesion ³	11.82	SERPINE1 PLG F3
6	Hematopoietic Stem Cells and Lineage-specific Markers ⁶⁵	11.77	ITGA2B IFNG GP1BA CSF2
7	Senescence and autophagy in cancer ⁷⁴	11.73	SERPINE1 PLAT IFNG
8	Integrin signaling ⁶⁶ Show member pathways GRB2:SOS provides linkage to MAPK signaling for Integrins ⁶⁶ p130Cas linkage to MAPK signaling for integrins ⁶⁶ Platelet Aggregation (Plug Formation) ⁶⁶	11.68	VWF ITGA2B GP1BA
9	Angiogenesis (CST) ³	11.64	VWF NOS3 F3
10	Cell adhesion_ECM remodeling ²²	11.46	SERPINE1 PLG PLAT
11	Platelet Aggregation Inhibitor Pathway, Pharmacodynamics ⁶⁰	11.26	VWF P2RY12 ITGA2B GP6 F2R
12	Beta2 integrin cell surface interactions ⁶¹	11.1	PLAT GP1BA F10
13	amb2 Integrin signaling ⁶¹	11.07	SELP PLG PLAT
14	Platelet Adhesion to exposed collagen ⁶⁶ Show member pathways GP1b-IX-V activation signalling ⁶⁶	10.98	VWF GP6 GP1BA
15	Selective expression of chemokine receptors during T-cell polarization ⁷⁴	10.72	IFNG CSF2
16	Dissolution of Fibrin Clot ⁶⁶	10.55	SERPINE1 PLG PLAT

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GO Terms for Carotid Artery Thrombosis

Cellular components related to Carotid Artery Thrombosis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	extracellular region	GO:0005576	10.34	CSF2 F10 F11 F2R F3 IFNG
2	collagen-containing extracellular matrix	GO:0062023	10	VWF SERPINE1 SERPINC1 PLG PLAT F3
3	platelet alpha granule lumen	GO:0031093	9.88	VWF SERPINE1 PLG
4	cell surface	GO:0009986	9.86	PLG PLAT P2RY12 ITGA2B GP6 GP1BA
5	extracellular space	GO:0005615	9.7	CSF2 F10 F11 F3 GP1BA IFNG
6	serine protease inhibitor complex	GO:0097180	9.67	SERPINE1 PLAT
7	obsolete intrinsic component of external side of plasma membrane	GO:0031233	9.16	F10 F3

Biological processes related to Carotid Artery Thrombosis according to GeneCards Suite gene sharing:

(show all 15)

#	Name	GO ID	Score	Top Affiliating Genes
1	platelet activation	GO:0030168	10.02	F2R GP1BA GP6 P2RY12 VWF
2	positive regulation of interleukin-8 production	GO:0032757	9.99	SERPINE1 F3 F2R
3	blood coagulation	GO:0007596	9.93	F10 F11 F2R F3 GP1BA GP6
4	fibrinolysis	GO:0042730	9.86	SERPINE1 PLG PLAT GP1BA
5	plasminogen activation	GO:0031639	9.85	PLAT F11
6	negative regulation of fibrinolysis	GO:0051918	9.85	SERPINE1 PLG PLAT
7	positive regulation of platelet activation	GO:0010572	9.84	SELP GP1BA
8	thrombin-activated receptor signaling pathway	GO:0070493	9.83	GP1BA F2R
9	negative regulation of plasminogen activation	GO:0010757	9.8	PLAT SERPINE1
10	response to fluid shear stress	GO:0034405	9.78	CSF2 NOS3
11	positive regulation of interleukin-23 production	GO:0032747	9.76	IFNG CSF2
12	positive regulation of fibrinolysis	GO:0051919	9.73	PLG F11
13	trans-synaptic signaling by BDNF, modulating synaptic transmission	GO:0099183	9.71	PLG PLAT
14	regulation of blood coagulation	GO:0030193	9.63	SERPINC1 GP1BA F2R F11
15	hemostasis	GO:0007599	9.4	F10 F11 F2R F3 GP1BA GP6

Molecular functions related to Carotid Artery Thrombosis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	protease binding	GO:0002020	9.76	VWF SERPINE1 SERPINC1 F3
2	thrombin-activated receptor activity	GO:0015057	9.56	GP1BA F2R
3	serine-type peptidase activity	GO:0008236	9.35	PLG PLAT F11 F10
4	serine-type endopeptidase activity	GO:0004252	9.32	PLG PLAT F3 F11 F10

Sources

Sources for Carotid Artery Thrombosis

¹ BitterDB

² CDC

³ Cell Signaling Technology

⁴ ClinicalTrials

⁵ ClinVar

⁶ CNVD

⁷ Cochrane Library

⁸ Cosmic

⁹ dbSNP

¹⁰ DGIdb

¹¹ Disease Ontology

¹² diseasecard

¹³ DiseaseEnhancer

¹⁴ DISEASES

¹⁵ DrugBank

¹⁶ EFO

¹⁷ ExPASy

¹⁸ FMA

¹⁹ GARD

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ GenomeRNAi

²⁶ GEO DataSets

²⁷ GO

²⁸ GTR

²⁹ HMDB

³⁰ HPO

³¹ ICD10

³² ICD10 via Orphanet

³³ ICD11

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ LifeMap

³⁷ LncRNADisease

³⁸ LOVD

³⁹ MalaCards

⁴⁰ MedGen

⁴¹ MedlinePlus

⁴² MedlinePlus Genetics

⁴³ MeSH

⁴⁴ MESH via Orphanet

⁴⁵ MGI

⁴⁶ miR2Disease

⁴⁷ NCBI Bookshelf

⁴⁸ NCI

⁴⁹ NCIt

⁵⁰ NDF-RT

⁵¹ NIH Clinical Center

⁵² NINDS

⁵³ Novoseek

⁵⁴ Novus Biologicals

⁵⁵ ODiseA

⁵⁶ OMIM via Orphanet

⁵⁷ OMIM® (Updated 08-Dec-2022)

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubChem

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ WikiPathways

⁷⁵ Wikipedia

MCID: CRT004 MIFTS: 38	Carotid Artery Thrombosis Categories: Blood diseases, Cardiovascular diseases, Neuronal diseases	Data Licensing For inquiries, contact: [email protected]
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