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MCID: CRT001
MIFTS: 25

Carotid Body Cancer

Categories: Cancer diseases, Cardiovascular diseases
Genes Tissues Related diseases Publications Pathways
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Aliases & Classifications for Carotid Body Cancer

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MalaCards integrated aliases for Carotid Body Cancer:

Name: Carotid Body Cancer 12 15
Malignant Carotid Body Paraganglioma 12
Malignant Neoplasm of Carotid Body 71
Malignant Carotid Body Tumor 12
Cancer of Carotid Body 12

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Cardiovascular diseases
See all MalaCards categories (disease lists)
ICD10: 32


External Ids:

Disease Ontology 12 DOID:8731
ICD9CM 34 194.5
NCIt 49 C3574
SNOMED-CT 67 447883002
ICD10 32 C75.4
UMLS 71 C0153656
Sources

Summaries for Carotid Body Cancer

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Disease Ontology : 12 A vascular cancer that is characterized by an encapsulated, firm round mass at the bifurcation of the common carotid artery.

MalaCards based summary : Carotid Body Cancer, also known as malignant carotid body paraganglioma, is related to paraganglioma and malignant melanocytic neoplasm of the peripheral nerve sheath. An important gene associated with Carotid Body Cancer is ENO2 (Enolase 2), and among its related pathways/superpathways is Neuroscience. Affiliated tissues include thyroid.

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Related Diseases for Carotid Body Cancer

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Diseases related to Carotid Body Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 280)
# Related Disease Score Top Affiliating Genes
1 paraganglioma 28.6 TG SYP SST ENO2 CHGA CALCA
2 malignant melanocytic neoplasm of the peripheral nerve sheath 10.4 SYP ENO2
3 sinonasal undifferentiated carcinoma 10.4 SYP ENO2
4 cerebral neuroblastoma 10.4 SYP ENO2
5 papillary tumor of the pineal region 10.4 SYP ENO2
6 pineal region teratoma 10.4 SYP ENO2
7 intracranial primitive neuroectodermal tumor 10.4 SYP ENO2
8 bile duct mucinous adenocarcinoma 10.4 SYP ENO2
9 extraosseous ewings sarcoma-primitive neuroepithelial tumor 10.4 SYP ENO2
10 cerebellopontine angle primitive neuroectodermal tumor 10.4 SYP ENO2
11 nodular prostate 10.4 SYP ENO2
12 cerebellar liponeurocytoma 10.4 SYP ENO2
13 papillary ependymoma 10.4 SYP ENO2
14 jejunal neoplasm 10.4 SYP ENO2
15 frontal lobe neoplasm 10.4 SYP ENO2
16 myoblastoma 10.4 SYP ENO2
17 pineal parenchymal tumor of intermediate differentiation 10.4 SYP ENO2
18 optic nerve astrocytoma 10.4 SYP ENO2
19 adrenal neuroblastoma 10.4 SYP ENO2
20 orbital cancer 10.4 SYP ENO2
21 endobronchial leiomyoma 10.4 SYP ENO2
22 spinal cord oligodendroglioma 10.4 SYP ENO2
23 lung meningioma 10.4 SYP NKX2-1
24 clear cell ependymoma 10.4 SYP ENO2
25 rhabdoid meningioma 10.4 SYP ENO2
26 bladder lateral wall cancer 10.4 SYP ENO2
27 cerebrovascular benign neoplasm 10.4 SYP ENO2
28 vaginal glandular tumor 10.4 ENO2 CHGA
29 extraosseous ewing sarcoma 10.4 SYP ENO2
30 cerebellum cancer 10.4 SYP ENO2
31 endobronchial lipoma 10.4 SYP ENO2
32 ureter transitional cell carcinoma 10.4 ENO2 CHGA
33 cerebellar medulloblastoma 10.4 SYP ENO2
34 central nervous system primitive neuroectodermal neoplasm 10.4 SYP ENO2
35 pineal gland cancer 10.3 SYP ENO2
36 gangliocytoma 10.3 SYP ENO2
37 primary hepatic neuroendocrine carcinoma 10.3 SYP CHGA
38 ependymoblastoma 10.3 SYP ENO2
39 goblet cell carcinoid 10.3 ENO2 CHGA
40 extraosseous chondrosarcoma 10.3 SYP ENO2
41 acinar cell cystadenocarcinoma 10.3 SYP CHGA
42 vulvar eccrine porocarcinoma 10.3 SYP CHGA
43 nodular ganglioneuroblastoma 10.3 ENO2 CHGA
44 ovarian small cell carcinoma 10.3 SYP ENO2
45 cervical large cell neuroendocrine carcinoma 10.3 SYP CHGA
46 cystic basal cell carcinoma 10.3 SYP ENO2
47 ewing sarcoma of bone 10.3 ENO2 CHGA
48 mixed ductal-endocrine carcinoma 10.3 SYP CHGA
49 melanotic neuroectodermal tumor 10.3 SYP ENO2
50 pancreatic serous cystadenocarcinoma 10.3 SYP CHGA

Graphical network of the top 20 diseases related to Carotid Body Cancer:



Diseases related to Carotid Body Cancer
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Symptoms & Phenotypes for Carotid Body Cancer

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Drugs & Therapeutics for Carotid Body Cancer

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Search Clinical Trials , NIH Clinical Center for Carotid Body Cancer

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Genetic Tests for Carotid Body Cancer

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Anatomical Context for Carotid Body Cancer

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MalaCards organs/tissues related to Carotid Body Cancer:

40
Thyroid
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Publications for Carotid Body Cancer

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Articles related to Carotid Body Cancer:

(show all 25)
# Title Authors PMID Year
1
Distinct features of malignant carotid body tumors and surgical techniques for challengeable lesions: a case series of 11 patients. 61
31807890 2020
2
Malignant carotid body tumor presenting with myelopathy: case report. 61
26722959 2016
3
[Diagnostic and therapeutic analysis of malignant carotid body tumors]. 61
24854749 2014
4
Giant malignant carotid body tumor in a 40 years old woman: a case report from Gondar University Hospital. 61
24696980 2013
5
Malignant carotid body tumor with systemic metastases. 61
21774445 2011
6
[Clinical and pathological analysis of malignant carotid body tumor]. 61
18959263 2008
7
Multiple osseous metastases of a carotid body tumor in a dog. 61
17409648 2007
8
[Surgery of the carotid artery: a retrospective study of 35 consecutive cases]. 61
16620623 2006
9
Recurrent malignant carotid body tumor: report of one case and review of the literature. 61
16313851 2005
10
Malignant carotid body tumor. 61
14999807 2004
11
Malignant carotid body tumor: a case report. 61
16027492 2004
12
Successful exclusion of a high internal carotid pseudoaneurysm using the Wallgraft endoprosthesis. 61
11907778 2002
13
Malignant carotid body tumors: report of three cases. 61
11201806 2001
14
Malignant carotid body tumor: a case report. 61
11013048 2000
15
[Lymphatic, hepatic and osseous metastasis of a carotid chemodectoma. Apropos of a case]. 61
9773002 1997
16
Characteristics, surgical management, and outcome in 17 carotid body tumors. 61
8955243 1996
17
Total internal carotid artery occlusion by a benign carotid body tumor: a rare occurrence. 61
4017612 1985
18
Malignant carotid body tumor. 61
1158626 1975
19
Malignant carotid body tumor with extradural metastases. 61
5424534 1970
20
Canine malignant carotid body tumor. 61
5461696 1970
21
Excision of malignant carotid body tumor: resection of carotid bifurcation with autogenous vein graft. 61
5347886 1969
22
Malignant carotid body tumor. Report of a case. 61
5778136 1969
23
[Malignant carotid body tumor (chemodectoma malignium)]. 61
5710866 1968
24
Malignant carotid body tumor with mandibular involvement. Report of a case. 61
5239100 1968
25
A MALIGNANT CAROTID BODY TUMOR IN AN AFRICAN. 61
14068964 1963
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Variations for Carotid Body Cancer

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Expression for Carotid Body Cancer

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Search GEO for disease gene expression data for Carotid Body Cancer.
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Pathways for Carotid Body Cancer

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Pathways related to Carotid Body Cancer according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Neuroscience 4
11.46 SYP NKX2-1 ENO2 CALCA
Sources

GO Terms for Carotid Body Cancer

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Cellular components related to Carotid Body Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.43 TG SST ENO2 CHGA CD59 CALCA
2 extracellular region GO:0005576 9.17 VWF TG SST SPINK5 CHGA CD59

Biological processes related to Carotid Body Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 thyroid gland development GO:0030878 8.62 TG NKX2-1

Molecular functions related to Carotid Body Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 8.8 TG SST CALCA
Sources

Sources for Carotid Body Cancer

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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