MCID: CRT043
MIFTS: 12

Carotid Intimal Medial Thickness 1

Categories: Genetic diseases

Aliases & Classifications for Carotid Intimal Medial Thickness 1

MalaCards integrated aliases for Carotid Intimal Medial Thickness 1:

Name: Carotid Intimal Medial Thickness 1 58 30 13 41 74
Intimal Medial Thickness of Internal Carotid Artery 58
Cimt1 58

Characteristics:

HPO:

33
carotid intimal medial thickness 1:
Inheritance polygenic inheritance


Classifications:



External Ids:

OMIM 58 609338
MedGen 43 C1836302
UMLS 74 C1836302

Summaries for Carotid Intimal Medial Thickness 1

MalaCards based summary : Carotid Intimal Medial Thickness 1, is also known as intimal medial thickness of internal carotid artery. An important gene associated with Carotid Intimal Medial Thickness 1 is PPARG (Peroxisome Proliferator Activated Receptor Gamma). The drugs Lycopene and Lutein have been mentioned in the context of this disorder. Related phenotype is increased carotid artery intimal medial thickness.

Description from OMIM: 609338

Related Diseases for Carotid Intimal Medial Thickness 1

Symptoms & Phenotypes for Carotid Intimal Medial Thickness 1

Human phenotypes related to Carotid Intimal Medial Thickness 1:

33
# Description HPO Frequency HPO Source Accession
1 increased carotid artery intimal medial thickness 33 HP:0012273

Clinical features from OMIM:

609338

Drugs & Therapeutics for Carotid Intimal Medial Thickness 1

Drugs for Carotid Intimal Medial Thickness 1 (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 6)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Lycopene Approved, Investigational Phase 2, Phase 3 502-65-8 53477748
2
Lutein Approved, Investigational, Nutraceutical Phase 2, Phase 3 127-40-2 6433159
3 Antioxidants Phase 2, Phase 3
4 Radiation-Protective Agents Phase 2, Phase 3
5 Protective Agents Phase 2, Phase 3
6 Anti-Inflammatory Agents Phase 2, Phase 3

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Effects of Lutein Supplementation on Subclinical Atherosclerosis Completed NCT01534533 Phase 2, Phase 3
2 PERIODONTITIS AND VASCULAR DYSFUNCTION Recruiting NCT03072342 Not Applicable
3 Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy Enrolling by invitation NCT02694094

Search NIH Clinical Center for Carotid Intimal Medial Thickness 1

Genetic Tests for Carotid Intimal Medial Thickness 1

Genetic tests related to Carotid Intimal Medial Thickness 1:

# Genetic test Affiliating Genes
1 Carotid Intimal Medial Thickness 1 30 PPARG

Anatomical Context for Carotid Intimal Medial Thickness 1

Publications for Carotid Intimal Medial Thickness 1

Variations for Carotid Intimal Medial Thickness 1

Expression for Carotid Intimal Medial Thickness 1

Search GEO for disease gene expression data for Carotid Intimal Medial Thickness 1.

Pathways for Carotid Intimal Medial Thickness 1

GO Terms for Carotid Intimal Medial Thickness 1

Sources for Carotid Intimal Medial Thickness 1

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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