CIMT1
MCID: CRT043
MIFTS: 9

Carotid Intimal Medial Thickness 1 (CIMT1)

Categories: Genetic diseases

Aliases & Classifications for Carotid Intimal Medial Thickness 1

MalaCards integrated aliases for Carotid Intimal Medial Thickness 1:

Name: Carotid Intimal Medial Thickness 1 57 29 13 40 73
Intimal Medial Thickness of Internal Carotid Artery 57
Cimt1 57

Characteristics:

HPO:

32
carotid intimal medial thickness 1:
Inheritance polygenic inheritance


Classifications:



External Ids:

OMIM 57 609338
MedGen 42 C1836302
UMLS 73 C1836302

Summaries for Carotid Intimal Medial Thickness 1

MalaCards based summary : Carotid Intimal Medial Thickness 1, is also known as intimal medial thickness of internal carotid artery. An important gene associated with Carotid Intimal Medial Thickness 1 is PPARG (Peroxisome Proliferator Activated Receptor Gamma). The drugs Lycopene and Lutein have been mentioned in the context of this disorder. Related phenotype is increased carotid artery intimal medial thickness.

Description from OMIM: 609338

Related Diseases for Carotid Intimal Medial Thickness 1

Symptoms & Phenotypes for Carotid Intimal Medial Thickness 1

Clinical features from OMIM:

609338

Human phenotypes related to Carotid Intimal Medial Thickness 1:

32
# Description HPO Frequency HPO Source Accession
1 increased carotid artery intimal medial thickness 32 HP:0012273

Drugs & Therapeutics for Carotid Intimal Medial Thickness 1

Drugs for Carotid Intimal Medial Thickness 1 (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Lycopene Approved, Investigational Phase 2, Phase 3 502-65-8 446925
2
Lutein Approved, Investigational, Nutraceutical Phase 2, Phase 3 127-40-2 6433159
3 Antioxidants Phase 2, Phase 3
4 Radiation-Protective Agents Phase 2, Phase 3
5 Protective Agents Phase 2, Phase 3

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Effects of Lutein Supplementation on Subclinical Atherosclerosis Completed NCT01534533 Phase 2, Phase 3
2 PERIODONTITIS AND VASCULAR DYSFUNCTION Recruiting NCT03072342 Not Applicable
3 Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy Enrolling by invitation NCT02694094

Search NIH Clinical Center for Carotid Intimal Medial Thickness 1

Genetic Tests for Carotid Intimal Medial Thickness 1

Genetic tests related to Carotid Intimal Medial Thickness 1:

# Genetic test Affiliating Genes
1 Carotid Intimal Medial Thickness 1 29 PPARG

Anatomical Context for Carotid Intimal Medial Thickness 1

Publications for Carotid Intimal Medial Thickness 1

Variations for Carotid Intimal Medial Thickness 1

Expression for Carotid Intimal Medial Thickness 1

Search GEO for disease gene expression data for Carotid Intimal Medial Thickness 1.

Pathways for Carotid Intimal Medial Thickness 1

GO Terms for Carotid Intimal Medial Thickness 1

Sources for Carotid Intimal Medial Thickness 1

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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