MCID: CRT013
MIFTS: 53

Carotid Stenosis

Categories: Cardiovascular diseases, Neuronal diseases

Aliases & Classifications for Carotid Stenosis

MalaCards integrated aliases for Carotid Stenosis:

Name: Carotid Stenosis 12 56 45 15 74
Carotid Artery Stenosis 12 6 15
Stenosis, Carotid Artery 12

Classifications:



External Ids:

Disease Ontology 12 DOID:13001
MeSH 45 D016893
NCIt 51 C95804
SNOMED-CT 69 64586002
UMLS 74 C0007282

Summaries for Carotid Stenosis

MalaCards based summary : Carotid Stenosis, also known as carotid artery stenosis, is related to amaurosis fugax and coronary artery anomaly. An important gene associated with Carotid Stenosis is CDKN2B-AS1 (CDKN2B Antisense RNA 1), and among its related pathways/superpathways are Selenium Micronutrient Network and Spinal Cord Injury. The drugs Clopidogrel and Atorvastatin have been mentioned in the context of this disorder. Affiliated tissues include brain, heart and testes, and related phenotypes are Decreased free cholesterol and homeostasis/metabolism

Wikipedia : 77 Carotid artery stenosis is a narrowing or constriction of any part of the carotid arteries, usually... more...

Related Diseases for Carotid Stenosis

Diseases related to Carotid Stenosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 224)
# Related Disease Score Top Affiliating Genes
1 amaurosis fugax 30.5 MMP9 MTHFR
2 coronary artery anomaly 30.0 ACE CRP F7 LPA SELP
3 aortic valve disease 2 30.0 ACE CRP SPP1 TNFRSF11B
4 peripheral vascular disease 30.0 ACE CRP LPA SELP
5 aortic aneurysm, familial abdominal, 1 29.8 APOE CDKN2B-AS1 MMP1 MMP9
6 intermittent claudication 29.8 ACE CRP SELP
7 takayasu arteritis 29.7 CRP MMP9 TNF
8 kawasaki disease 29.7 CRP MMP9 TNF
9 vascular dementia 29.6 ACE APOE MTHFR TNF
10 arteries, anomalies of 29.5 ACE APOE CRP LPA MMP9 SELP
11 hypercholesterolemia, familial 29.5 ACE APOE CRP LPA
12 thrombosis 29.4 F7 MTHFR SELP TFPI
13 carotid artery disease 29.4 ACE APOE CRP LPA MMP1 MMP9
14 sleep apnea 29.3 ACE APOE CRP S100B TNF
15 kidney disease 29.3 ACE APOE CRP LPA SPP1 TNFRSF11B
16 peripheral artery disease 29.2 ACE CDKN2B-AS1 CRP SELP TNFRSF11B
17 atherosclerosis susceptibility 29.1 APOE CDKN2B-AS1 CRP LPA TNF
18 chronic kidney failure 29.1 ACE CRP LPA MTHFR SPP1 TNFRSF11B
19 arteriosclerosis 28.9 ACE APOE CRP LPA MMP9 SELP
20 diabetes mellitus 28.9 ACE CDKN2B-AS1 CRP LPA TNF
21 stroke, ischemic 28.9 ACE APOE CDKN2B-AS1 CRP F7 LPA
22 cerebrovascular disease 28.7 ACE APOE CRP F7 MMP9 MTHFR
23 ischemic heart disease 28.6 ACE APOE CRP F7 MTHFR TNF
24 heart disease 28.6 ACE APOE CRP F7 MTHFR S100B
25 coronary heart disease 1 28.5 ACE APOE CDKN2B-AS1 CRP LPA MTHFR
26 vascular disease 28.4 ACE APOE CRP LPA MMP9 MTHFR
27 myocardial infarction 27.2 ACE APOE CDKN2B-AS1 CRP F7 LPA
28 moyamoya disease 2 11.5
29 moyamoya disease 5 11.3
30 moyamoya disease 6 with or without achalasia 11.3
31 spastic entropion 10.4 MMP1 MMP9
32 chronic actinic dermatitis 10.4 MMP1 MMP9
33 lentigo maligna melanoma 10.4 MMP9 S100B
34 periodontitis, chronic 10.4 MMP1 TNFRSF11B
35 chronic venous insufficiency 10.3 MMP1 MMP9 SELP
36 chronic meningitis 10.3 CRP MMP9
37 internal hemorrhoid 10.3 MMP1 MMP9
38 osteoporotic fracture 10.3 MTHFR TNFRSF11B
39 ischemia 10.3
40 moderate and severe traumatic brain injury 10.3 ACE APOE
41 odontogenic myxoma 10.3 MMP1 MMP9 S100B
42 aortic disease 10.3 APOE CRP MMP9
43 preterm premature rupture of the membranes 10.3 CRP MMP1 MMP9
44 uremia 10.3 CRP SPP1 TNFRSF11B
45 mastoiditis 10.2 CRP MTHFR
46 head injury 10.2 APOE S100B
47 chromoblastomycosis 10.2 MMP1 MMP9
48 transient cerebral ischemia 10.2
49 autoimmune inner ear disease 10.2 MMP9 TNF
50 mesenteric vascular occlusion 10.2 F7 MTHFR

Graphical network of the top 20 diseases related to Carotid Stenosis:



Diseases related to Carotid Stenosis

Symptoms & Phenotypes for Carotid Stenosis

GenomeRNAi Phenotypes related to Carotid Stenosis according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased free cholesterol GR00340-A-2 8.8 APOE LPA SELP

MGI Mouse Phenotypes related to Carotid Stenosis:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.28 ACE APOE CRP F7 HABP2 MMP1
2 cardiovascular system MP:0005385 10.18 ACE APOE CRP F7 MMP9 SELP
3 immune system MP:0005387 10.18 ACE APOE CRP HABP2 MMP1 MMP9
4 growth/size/body region MP:0005378 10.16 ACE APOE F7 MMP9 MTHFR SELP
5 integument MP:0010771 9.97 APOE MMP9 MTHFR S100B SELP SPP1
6 mortality/aging MP:0010768 9.9 ACE APOE F7 HABP2 MMP9 MTHFR
7 limbs/digits/tail MP:0005371 9.8 APOE MMP9 MTHFR TFPI TNF TNFRSF11B
8 liver/biliary system MP:0005370 9.8 ACE APOE HABP2 MTHFR SELP SPP1
9 neoplasm MP:0002006 9.43 ACE MMP1 MMP9 SPP1 TNF TREM1
10 skeleton MP:0005390 9.28 APOE F7 MMP9 MTHFR SELP SPP1

Drugs & Therapeutics for Carotid Stenosis

Drugs for Carotid Stenosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 193)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Clopidogrel Approved Phase 4,Phase 3,Phase 2,Not Applicable 120202-66-6, 113665-84-2 60606
2
Atorvastatin Approved Phase 4,Phase 3,Phase 2,Not Applicable 134523-00-5 60823
3
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 50-78-2 2244
4
Propofol Approved, Investigational, Vet_approved Phase 4 2078-54-8 4943
5
Remifentanil Approved Phase 4 132875-61-7 60815
6
Sevoflurane Approved, Vet_approved Phase 4 28523-86-6 5206
7
Acetaminophen Approved Phase 4 103-90-2 1983
8
Amlodipine Approved Phase 4,Phase 3 88150-42-9 2162
9
Benzocaine Approved, Investigational Phase 4,Phase 3 1994-09-7, 94-09-7 2337
10
tannic acid Approved Phase 4,Phase 3 1401-55-4
11
Cilostazol Approved, Investigational Phase 4 73963-72-1 2754
12
Evolocumab Approved Phase 4 1256937-27-5
13
Losartan Approved Phase 4 114798-26-4 3961
14
Angiotensin II Approved, Investigational Phase 4 11128-99-7, 68521-88-0, 4474-91-3 172198
15
Dexmedetomidine Approved, Vet_approved Phase 4 113775-47-6 5311068 68602
16
Melatonin Approved, Nutraceutical, Vet_approved Phase 4 73-31-4 896
17
Calcium Approved, Nutraceutical Phase 4,Phase 3,Phase 2,Not Applicable 7440-70-2 271
18 Antimetabolites Phase 4,Phase 3,Phase 2,Not Applicable
19 Anticholesteremic Agents Phase 4,Phase 3,Phase 2,Not Applicable
20 Hypolipidemic Agents Phase 4,Phase 3,Phase 2,Not Applicable
21 Purinergic P2 Receptor Antagonists Phase 4,Phase 3,Phase 2,Not Applicable
22 Lipid Regulating Agents Phase 4,Phase 3,Phase 2,Not Applicable
23 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 4,Phase 3,Phase 2,Not Applicable
24 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Not Applicable
25 Purinergic P2Y Receptor Antagonists Phase 4,Phase 3,Phase 2,Not Applicable
26 Platelet Aggregation Inhibitors Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
27 Central Nervous System Depressants Phase 4,Not Applicable
28 Protective Agents Phase 4,Phase 2,Not Applicable
29 Peripheral Nervous System Agents Phase 4,Phase 2,Not Applicable
30 Analgesics Phase 4,Phase 2,Not Applicable
31 Anesthetics Phase 4,Phase 2,Not Applicable
32 Analgesics, Non-Narcotic Phase 4,Phase 2,Not Applicable
33 Antipyretics Phase 4,Phase 2,Not Applicable
34 Antirheumatic Agents Phase 4,Phase 2,Not Applicable
35 Anti-Inflammatory Agents, Non-Steroidal Phase 4,Phase 2,Not Applicable
36 Bronchodilator Agents Phase 4,Not Applicable
37 Fibrinolytic Agents Phase 4,Phase 3,Phase 2,Not Applicable
38 Respiratory System Agents Phase 4,Not Applicable
39 Anti-Inflammatory Agents Phase 4,Phase 2,Not Applicable
40 Autonomic Agents Phase 4,Not Applicable
41 Cyclooxygenase Inhibitors Phase 4,Phase 2,Not Applicable
42 Anti-Asthmatic Agents Phase 4,Not Applicable
43 Immunoglobulins Phase 4,Phase 2
44 Antibodies, Monoclonal Phase 4,Phase 2
45 Antibodies Phase 4,Phase 2
46 Immunologic Factors Phase 4,Phase 2
47 Adrenergic alpha-Agonists Phase 4,Not Applicable
48 Adrenergic Agents Phase 4,Phase 2,Not Applicable
49 Adrenergic Agonists Phase 4,Not Applicable
50 Radiopharmaceuticals Phase 4,Phase 2

Interventional clinical trials:

(show top 50) (show all 247)
# Name Status NCT ID Phase Drugs
1 Comparison of Staged Angioplasty and Routine Single-stage Stenting (CAS) in the Treatment of Carotid Artery Stenosis Unknown status NCT02224209 Phase 4
2 Clopidogrel and Atorvastatin Treatment During Carotid Artery Stenting Unknown status NCT01572623 Phase 4 Clopidogrel;Atorvastatin
3 Early Warning and Optimization Strategy in Carotid Endarterectomy Unknown status NCT01210937 Phase 4
4 Comparing Carotid Stenting With Endarterectomy in Severe Asymptomatic Carotid Stenosis Completed NCT00772278 Phase 4
5 Melatonin in Patients Under Carotid Endarterectomy Completed NCT03115034 Phase 4 Melatonin;placebo
6 Effect on Cerebral Oxygenation by Sevoflurane or Propofol Using Near-infrared Spectroscopy in Carotid Endarterectomy Completed NCT02609087 Phase 4 Sevoflurane;Propofol
7 Platelet Inhibition and Transcranial Doppler (TCD)-Detected Microemboli During and After Carotid Artery Stenting (CAS) in Asymptomatic Patients Prior to Cardiac Surgery Completed NCT01146301 Phase 4 Clopidogrel
8 Emboshield® and Xact® Post Approval Carotid Stent Trial (The EXACT Study) Completed NCT00287508 Phase 4
9 A Single Center of Carotid Stenting With Distal Protection for the Treatment of Obstructive Carotid Artery Disease Completed NCT00178672 Phase 4
10 Effect of IV Acetaminophen on Patients in the Neurocritical Care Unit Completed NCT01948505 Phase 4 Intravenous acetaminophen;Placebo for IV acetaminophen
11 Insulin Resistance in Patients After Carotid Revascularization Recruiting NCT03419767 Phase 4 Melatonin
12 High Dose Atorvastatin for Preventing Periprocedural Ischemic Brain Damage During Carotid Artery Stenting Recruiting NCT03079115 Phase 4 High-dose Atorvastatin;Conventional-dose Atorvastatin
13 Effect of Cilostazol on Carotid Atherosclerosis Estimated by 3D Ultrasound in Patients With Type 2 Diabetes Active, not recruiting NCT03248401 Phase 4 Cilostazol;Aspirin
14 Effect of Evolocumab on Carotid Plaque Composition in Asymptomatic Carotid Artery Stenosis (EVOCAR-1) Not yet recruiting NCT03931161 Phase 4 Evolocumab Auto-Injector [Repatha];Placebo Auto-Injector
15 Aggressive Medical Treatment Evaluation for Asymptomatic Carotid Artery Stenosis Terminated NCT00805311 Phase 4 atorvastatin, aspirin, losartan, amlodipine
16 Post-Approval Study of the NexStent Carotid Stent System and the FilterWire EZ Embolic Protection System: SONOMA Terminated NCT00478673 Phase 4
17 The Effects of Dexmedetomidine and Remifentanil on Carotid Patients Terminated NCT00335972 Phase 4 Remifentanil;Dexmedetomidine
18 Relation of Carotid Artery Plaque Inflammation, Covert Stroke and White Matter Disease Terminated NCT01236508 Phase 4
19 Clopidogrel Resistance and Embolism in Carotid Artery Stenting Unknown status NCT02133989 Phase 3 Ticlopidine + Ginko biloba;Clopidogrel
20 PROximal Protection VErsus NON-Protection in Carotid Artery Stenting Unknown status NCT01331473 Phase 3
21 EVA3S: Endarterectomy Versus Angioplasty in Patients With Severe Symptomatic Carotid Stenosis Completed NCT00190398 Phase 3
22 ViVEXX Carotid Revascularization Trial (VIVA) Completed NCT00417963 Phase 3
23 Carotid Artery Stenting With Protection Registry Completed NCT00318851 Phase 3
24 Progression of Carotid Artery Atheroma in Moderately Hypercholesterolemic Subjects Completed NCT00654394 Phase 3 Rosuvastatin
25 Gadobutrol Enhanced MRA of the Supra-aortic Vessels Completed NCT01344447 Phase 3 Gadobutrol (Gadovist, BAY86-4875)
26 GORE® Embolic Filter in Carotid Stenting for High Risk Surgical Subjects (EMBOLDEN) Completed NCT00766493 Phase 3
27 SONOlysis in Prevention of Brain Infarctions dUring Carotid Stenting and caroTid EndaRterectomy Completed NCT01591005 Phase 3
28 GORE Embolic Protection With Reverse Flow Completed NCT00594100 Phase 3
29 Coronary Angiography Before Elective Carotid Endarterectomy in Patients With Asymptomatic Coronary Artery Disease Completed NCT02260453 Phase 3
30 IMaging Della PLAcca Carotidea Completed NCT03333330 Phase 3 Visipaque 320 and SonoVue
31 Clear-Road Trial, Investigating the Efficacy of the RoadSaver Stent Completed NCT02529345 Phase 2, Phase 3
32 Carotid Revascularization With ev3 Arterial Technology Evolution (CREATE) Trial Completed NCT00619775 Phase 3
33 ACCULINK for Revascularization of Carotids in High Risk Patients "The ARCHeR Trial" Completed NCT00180518 Phase 2, Phase 3
34 Molecular and Clinical Effects of Green Tea and Fermented Papaya Preparation on Diabetes and Cardiovascular Diseases Completed NCT01248143 Phase 2, Phase 3
35 Statin Neuroprotection and Carotid Endarterectomy: Safety, Feasibility and Outcomes Recruiting NCT02850081 Phase 3 Statin;Atorvastatin
36 " Endarterectomy Combined With Optimal Medical Therapy (OMT) vs OMT Alone in Patients With Asymptomatic Severe Atherosclerotic Carotid Artery Stenosis at Higher-than-average Risk of Ipsilateral Stroke " Not yet recruiting NCT02841098 Phase 3 Optimal medical therapy alone
37 Abciximab for Prevention of Stroke Recurrence Before Endarterectomy in Symptomatic Carotid Stenosis Terminated NCT00126139 Phase 3 Abciximab
38 Evaluation of the TriActiv ProGuard System During Carotid Artery Stenting Terminated NCT00395785 Phase 2, Phase 3
39 Medico-economic Evaluation of Preoperative Cerebral Oximetry Monitoring During Carotid Endarterectomy Terminated NCT01415648 Phase 3
40 Atherosclerosis Underlying Development Assessed by Intima-Media Thickness in Patients on Rimonabant Terminated NCT00228176 Phase 3 Rimonabant;Placebo (for Rimonabant)
41 Phase II Randomized Placebo-controlled Study With Vitamin K2 in Asymptomatic Calcified Carotid Stenosis Unknown status NCT01923012 Phase 2 Vitamin K2 (Menaquinone)
42 The Use of Anti-CD4 mAb-Fragment for Imaging of Local Inflammation in Patients With Carotid Artery Stenosis Unknown status NCT00904254 Phase 2
43 Study on Vulnerable Plaque of Carotid Artery With Chinese Herbal and Insects Medicine Unknown status NCT03072225 Phase 2 Herbal Medicine C-117;The Placebo of Herbal Medicine C-117
44 Revacept in Symptomatic Carotid Stenosis (Revacept/CS/02) Completed NCT01645306 Phase 2 Revacept;Placebo
45 Recurrent Carotid Stenosis Completed NCT00000527 Phase 2 aspirin;dipyridamole
46 Protective Effects of Long-term Remote Limb Ischemic Preconditioning For Carotid Artery Stenting Completed NCT01654666 Phase 2
47 Study Effect of VIA-2291 on Atherosclerotic Vascular Inflammation in Patients Undergoing Elective Carotid Endarterectomy Completed NCT00352417 Phase 2 VIA-2291;Placebo
48 Asymptomatic Carotid Artery Plaque Study (ACAPS) Completed NCT00000469 Phase 2 aspirin;lovastatin
49 Neuroprotective and Cardioprotective Effects Of Palm Vitamin E Tocotrienols Completed NCT00753532 Phase 2
50 Ticagrelor Versus Clopidogrel in Carotid Artery Stenting Recruiting NCT02677545 Phase 2 Ticagrelor;Clopidogrel;Aspirin

Search NIH Clinical Center for Carotid Stenosis

Cochrane evidence based reviews: carotid stenosis

Genetic Tests for Carotid Stenosis

Anatomical Context for Carotid Stenosis

MalaCards organs/tissues related to Carotid Stenosis:

42
Brain, Heart, Testes, Liver, Endothelial, Eye, Neutrophil

Publications for Carotid Stenosis

Articles related to Carotid Stenosis:

(show top 50) (show all 2955)
# Title Authors Year
1
Carotid Artery Disease in Post-Stroke Survivors and Effects of Enriched Environment on Stroke Pathology in a Mouse Model of Carotid Artery Stenosis. ( 30947376 )
2019
2
Management of De Novo Carotid Stenosis and Postintervention Restenosis-Carotid Endarterectomy Versus Carotid Artery Stenting-a Review of Literature. ( 30793257 )
2019
3
Timing of Carotid Endarterectomy for Symptomatic Carotid Stenosis: A Snapshot of Current Trends and Systematic Review of Literature on Changing Paradigm towards Early Surgery. ( 30799491 )
2019
4
Peak systolic velocity for calcified plaques fails to estimate carotid stenosis degree. ( 30802575 )
2019
5
Influence of stenting with open-cell stents vs close-cell stents on the outcomes of patients with bilateral carotid stenosis. ( 30839407 )
2019
6
De novo aneurysm formation after a Wingspan stenting of intracranial carotid stenosis: a computational hemodynamic analysis. ( 30877006 )
2019
7
Reduced facial swelling and incision numbness after Q-modified eversion carotid endarterectomy in patients with severe carotid stenosis. ( 30878744 )
2019
8
Fluoroscopic angiography quantifies delay in cerebral circulation time and requires less radiation in carotid stenosis patients: A pilot study. ( 30893249 )
2019
9
Age but not sex is associated with higher risk of in-hospital stroke or death after carotid artery stenting in symptomatic and asymptomatic carotid stenosis. ( 30905363 )
2019
10
Comparison of outcomes after carotid endarterectomy between type 2 diabetic and non-diabetic patients with significant carotid stenosis. ( 30909911 )
2019
11
The TXA2R rs1131882, P2Y1 rs1371097 and GPIIIa rs2317676 three-loci interactions may increase the risk of carotid stenosis in patients with ischemic stroke. ( 30914039 )
2019
12
Carotid stenosis prevalence after radiotherapy in nasopharyngeal carcinoma: A meta-analysis. ( 30935575 )
2019
13
High-Frequency Fluctuations in Post-stenotic Patient Specific Carotid Stenosis Fluid Dynamics: A Computational Fluid Dynamics Strategy Study. ( 30937853 )
2019
14
Contemporary prevalence of carotid stenosis in patients presenting with ischaemic stroke. ( 30938840 )
2019
15
Asymptomatic Carotid Stenosis Is Associated With Circadian and Other Variability in Embolus Detection. ( 31040812 )
2019
16
Presenting time-based risks of stroke and death for Patients facing carotid stenosis treatment options: Patients prefer pie charts over icon arrays. ( 31101429 )
2019
17
Paravertebral Collateral Arteries in Patients with Carotid Stenosis: Is There a Safe Space for Transforaminal Cervical Nerve Root Injections? ( 31101951 )
2019
18
It is safe to use transdermal glyceryl trinitrate to lower blood pressure in patients with acute ischaemic stroke with carotid stenosis. ( 31105976 )
2019
19
Prevalence of Carotid Stenosis and Incidence of Ischemic Stroke in Patients Undergoing Non-Coronary Cardiac Surgery. ( 31112018 )
2019
20
Increased Leucocyte-Platelet Complex Formation in Recently Symptomatic versus Asymptomatic Carotid Stenosis Patients and in Micro-emboli Negative Subgroups. ( 30769362 )
2019
21
Long-term outcomes of stenting and endarterectomy for symptomatic carotid stenosis: a preplanned pooled analysis of individual patient data. ( 30738706 )
2019
22
Silent Intracerebral Hemorrhage in Patients Randomized to Stenting or Endarterectomy for Symptomatic Carotid Stenosis. ( 30732448 )
2019
23
Systematic and Comprehensive Comparison of Incidence of Restenosis between Carotid Endarterectomy and Carotid Artery Stenting in the Patients with Atherosclerotic Carotid Stenosis. ( 30710719 )
2019
24
Changes in Cognition, Depression and Quality of Life after Carotid Stenosis Treatment. ( 30706811 )
2019
25
Internal Carotid Stenosis Associated with Compression by Hyoid Bone. ( 30684622 )
2019
26
Risk Prediction Tools to Improve Patient Selection for Carotid Endarterectomy Among Patients With Asymptomatic Carotid Stenosis. ( 30624562 )
2019
27
A Rare Case of Symptomatic Carotid Stenosis Caused by Mechanical Stimulation by Thyroid Cartilage and Frequent Swimming. ( 30527791 )
2019
28
Optimal Antiplatelet Therapy in Moderate to Severe Asymptomatic and Symptomatic Carotid Stenosis: A Comprehensive Review of the Literature. ( 30414802 )
2019
29
Risk factors for hyperperfusion-induced intracranial hemorrhage after carotid artery stenting in patients with symptomatic severe carotid stenosis evaluation. ( 30368473 )
2019
30
Carotid Stenosis: Utility of Diagnostic Angiography. ( 30336298 )
2019
31
Efficacy of Carotid Endarterectomy for Mild (<50%) Symptomatic Carotid Stenosis with Unstable Plaque. ( 30244188 )
2019
32
Carotid Artery Calcification on Orthopantomograms (CACO Study) - is it indicative of carotid stenosis? ( 30216463 )
2019
33
Outcomes of Stenting versus Endarterectomy for Symptomatic Extracranial Carotid Stenosis: A Retrospective Multicenter Study in Korea. ( 30092433 )
2019
34
Carotid Endarterectomy versus Carotid Stenting or Best Medical Treatment in Asymptomatic Patients with Significant Carotid Stenosis: A meta-analysis. ( 30057288 )
2019
35
Neutrophil to Lymphocyte Ratio as a Predictor of Restenosis After Angioplasty and Stenting for Asymptomatic Carotid Stenosis. ( 29940783 )
2019
36
Carotid artery stenosis, diabetes mellitus, and TCD4+ lymphocyte subpopulations. ( 30414241 )
2019
37
Prevalence of carotid artery stenosis in ischaemic heart disease patients in Bangladesh. ( 30800301 )
2019
38
Association between carotid artery stenosis and peripheral artery disease: Evaluation by screening carotid ultrasonography (cross-sectional study). ( 30732131 )
2019
39
Reply to Letter by Dr Demirtas et al "Cerebrovascular Events in Stenting for Carotid Artery Stenosis". ( 30380908 )
2019
40
Long-term results of carotid stenting and risk factors in patients with severe carotid artery stenosis undergoing subsequent cardiac surgery. ( 30411845 )
2019
41
Pulse Wave Imaging in Carotid Artery Stenosis Human Patients in Vivo. ( 30442386 )
2019
42
Transfemoral Carotid Artery Stents Should Be Used with Caution in Patients with Asymptomatic Carotid Artery Stenosis. ( 30339900 )
2019
43
Different ST2 Serum Concentrations in Asymptomatic and Symptomatic Carotid Artery Stenosis. ( 30339898 )
2019
44
Impact of Carotid Artery Stenosis on Quality of Life: A Systematic Review. ( 30328068 )
2019
45
High Neutrophil to Lymphocyte Ratio and Platelet to Lymphocyte Ratio are Associated with Symptomatic Internal Carotid Artery Stenosis. ( 30268367 )
2019
46
Postoperative stroke after anterior cervical discectomy and fusion in patients with carotid artery stenosis: a statewide database analysis. ( 30244036 )
2019
47
Cerebrovascular Events in Stenting for Carotid Artery Stenosis. ( 30231619 )
2019
48
Shear rate is a better marker of symptomatic ischemic cerebrovascular events than velocity or diameter in severe carotid artery stenosis. ( 29941314 )
2019
49
Retinal vessel dynamic functionality in the eyes of asymptomatic patients with significant internal carotid artery stenosis. ( 31112024 )
2019
50
Usefulness of plateletcrit in the prediction of major adverse cardiac and cerebrovascular events in patients with carotid artery stenosis. ( 31027469 )
2019

Variations for Carotid Stenosis

ClinVar genetic disease variations for Carotid Stenosis:

6
# Gene Variation Type Significance SNP ID Assembly Location
1 RNF213 NM_001256071.2(RNF213): c.11659A> G (p.Lys3887Glu) single nucleotide variant Uncertain significance rs1555673862 GRCh38 Chromosome 17, 80363699: 80363699
2 RNF213 NM_001256071.2(RNF213): c.11659A> G (p.Lys3887Glu) single nucleotide variant Uncertain significance rs1555673862 GRCh37 Chromosome 17, 78337499: 78337499

Expression for Carotid Stenosis

Search GEO for disease gene expression data for Carotid Stenosis.

Pathways for Carotid Stenosis

GO Terms for Carotid Stenosis

Cellular components related to Carotid Stenosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.73 ACE APOE CRP F7 HABP2 MMP9
2 extracellular region GO:0005576 9.47 ACE APOE CRP F7 HABP2 LPA
3 extracellular matrix GO:0031012 9.46 APOE MMP1 MMP9 TNFRSF11B

Biological processes related to Carotid Stenosis according to GeneCards Suite gene sharing:

(show all 11)
# Name GO ID Score Top Affiliating Genes
1 negative regulation of gene expression GO:0010629 9.67 ACE APOE CDKN2B-AS1 TNF
2 proteolysis GO:0006508 9.63 ACE F7 HABP2 LPA MMP1 MMP9
3 extracellular matrix organization GO:0030198 9.56 MMP9 SPP1 TNF TNFRSF11B
4 regulation of neuronal synaptic plasticity GO:0048168 9.49 APOE S100B
5 leukocyte tethering or rolling GO:0050901 9.48 SELP TNF
6 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.46 APOE TNF
7 negative regulation of blood coagulation GO:0030195 9.43 APOE TFPI
8 low-density lipoprotein particle remodeling GO:0034374 9.4 APOE LPA
9 negative regulation of lipid storage GO:0010888 9.32 CRP TNF
10 leukocyte migration GO:0050900 9.02 MMP1 MMP9 SELP TNF TREM1
11 blood coagulation, extrinsic pathway GO:0007598 8.96 F7 TFPI

Molecular functions related to Carotid Stenosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 calcium ion binding GO:0005509 9.65 CRP F7 HABP2 S100B SELP
2 peptidase activity GO:0008233 9.63 ACE F7 HABP2 LPA MMP1 MMP9
3 serine-type endopeptidase activity GO:0004252 9.35 F7 HABP2 LPA MMP1 MMP9
4 tau protein binding GO:0048156 9.32 APOE S100B
5 endopeptidase activity GO:0004175 8.92 ACE F7 MMP1 MMP9

Sources for Carotid Stenosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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