MCID: CRT006
MIFTS: 19

Cartilage Cancer

Categories: Bone diseases, Cancer diseases

Aliases & Classifications for Cartilage Cancer

MalaCards integrated aliases for Cartilage Cancer:

Name: Cartilage Cancer 12 15
Chondrogenic Neoplasm 71

Classifications:



External Ids:

Disease Ontology 12 DOID:0060102
UMLS 71 C0476147

Summaries for Cartilage Cancer

Disease Ontology : 12 A connective tissue tumor that can be a benign chondroma or a maligannt chondrosarcoma.

MalaCards based summary : Cartilage Cancer, also known as chondrogenic neoplasm, is related to laryngeal cartilage cancer and migraine with or without aura 1. An important gene associated with Cartilage Cancer is AFAP1L2 (Actin Filament Associated Protein 1 Like 2), and among its related pathways/superpathways are Myometrial Relaxation and Contraction Pathways and Oxytocin signaling pathway. Affiliated tissues include bone.

Related Diseases for Cartilage Cancer

Diseases related to Cartilage Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 2, show less)
# Related Disease Score Top Affiliating Genes
1 laryngeal cartilage cancer 12.3
2 migraine with or without aura 1 8.4 RAMP3 RAMP2 RAMP1 CALCRL

Symptoms & Phenotypes for Cartilage Cancer

Drugs & Therapeutics for Cartilage Cancer

Search Clinical Trials , NIH Clinical Center for Cartilage Cancer

Genetic Tests for Cartilage Cancer

Anatomical Context for Cartilage Cancer

MalaCards organs/tissues related to Cartilage Cancer:

40
Bone

Publications for Cartilage Cancer

Articles related to Cartilage Cancer:

(showing 7, show less)
# Title Authors PMID Year
1
Extraskeletal mesenchymal chondrosarcoma arising in adductor magnus with metastatic foci. 61
30364375 2016
2
Ewing sarcoma ewsa protein regulates chondrogenesis of Meckel's cartilage through modulation of Sox9 in zebrafish. 61
25617839 2015
3
Intramuscular, extraskeletal mesenchymal chondrosarcoma. 61
23548257 2011
4
Type II collagen as specific marker for mesenchymal chondrosarcomas compared to other small cell sarcomas of the skeleton. 61
15731776 2005
5
Shark cartilage cancer treatments are pseudoscience. 61
15818787 2005
6
Shark cartilage, cancer and the growing threat of pseudoscience. 61
15574750 2004
7
Mesenchymal chondrosarcoma: an immunohistochemical study of 10 cases examining prognostic significance of proliferative activity and cellular differentiation. 61
15203726 2004

Variations for Cartilage Cancer

Expression for Cartilage Cancer

Search GEO for disease gene expression data for Cartilage Cancer.

Pathways for Cartilage Cancer

GO Terms for Cartilage Cancer

Cellular components related to Cartilage Cancer according to GeneCards Suite gene sharing:

(showing 6, show less)
# Name GO ID Score Top Affiliating Genes
1 integral component of plasma membrane GO:0005887 9.62 RAMP3 RAMP2 RAMP1 CALCRL
2 cell surface GO:0009986 9.54 RAMP3 RAMP2 RAMP1
3 lysosome GO:0005764 9.43 RAMP3 RAMP2 CALCRL
4 receptor complex GO:0043235 9.33 RAMP3 RAMP2 RAMP1
5 CGRP receptor complex GO:1990406 8.96 RAMP1 CALCRL
6 adrenomedullin receptor complex GO:1903143 8.8 RAMP3 RAMP2 CALCRL

Biological processes related to Cartilage Cancer according to GeneCards Suite gene sharing:

(showing 13, show less)
# Name GO ID Score Top Affiliating Genes
1 G protein-coupled receptor signaling pathway GO:0007186 9.83 RAMP3 RAMP2 RAMP1 CALCRL
2 protein transport GO:0015031 9.8 RAMP3 RAMP2 RAMP1 CALCRL
3 angiogenesis GO:0001525 9.76 RAMP3 RAMP2 RAMP1 CALCRL
4 intracellular protein transport GO:0006886 9.69 RAMP3 RAMP2 RAMP1
5 protein localization to plasma membrane GO:0072659 9.65 RAMP3 RAMP2 RAMP1
6 calcium ion transport GO:0006816 9.62 RAMP3 RAMP2 RAMP1 CALCRL
7 cellular response to hormone stimulus GO:0032870 9.58 RAMP3 RAMP2 RAMP1
8 adenylate cyclase-activating G protein-coupled receptor signaling pathway GO:0007189 9.56 RAMP3 RAMP2 RAMP1 CALCRL
9 regulation of G protein-coupled receptor signaling pathway GO:0008277 9.54 RAMP3 RAMP2 RAMP1
10 calcitonin gene-related peptide receptor signaling pathway GO:1990408 9.43 RAMP1 CALCRL
11 amylin receptor signaling pathway GO:0097647 9.33 RAMP3 RAMP2 RAMP1
12 receptor internalization GO:0031623 9.26 RAMP3 RAMP2 RAMP1 CALCRL
13 adrenomedullin receptor signaling pathway GO:1990410 8.8 RAMP3 RAMP2 CALCRL

Molecular functions related to Cartilage Cancer according to GeneCards Suite gene sharing:

(showing 6, show less)
# Name GO ID Score Top Affiliating Genes
1 coreceptor activity GO:0015026 9.43 RAMP3 RAMP2 RAMP1
2 calcitonin gene-related peptide receptor activity GO:0001635 9.37 RAMP1 CALCRL
3 protein transporter activity GO:0008565 9.33 RAMP3 RAMP2 RAMP1
4 adrenomedullin binding GO:1990409 9.32 RAMP2 CALCRL
5 amylin receptor activity GO:0097643 9.13 RAMP3 RAMP2 RAMP1
6 adrenomedullin receptor activity GO:0001605 8.8 RAMP3 RAMP2 CALCRL

Sources for Cartilage Cancer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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