MCID: CSC001
MIFTS: 26

Cascade Stomach

Categories: Gastrointestinal diseases

Aliases & Classifications for Cascade Stomach

MalaCards integrated aliases for Cascade Stomach:

Name: Cascade Stomach 12 15 71
Hourglass Stricture or Stenosis of Stomach 12

Classifications:



External Ids:

Disease Ontology 12 DOID:12234
ICD9CM 34 537.6
SNOMED-CT 67 54051005
ICD10 32 K31.2
UMLS 71 C0267183

Summaries for Cascade Stomach

MalaCards based summary : Cascade Stomach, also known as hourglass stricture or stenosis of stomach, is related to volvulus of midgut and peptic esophagitis. An important gene associated with Cascade Stomach is DLL3 (Delta Like Canonical Notch Ligand 3), and among its related pathways/superpathways are Proton Pump Inhibitor Pathway, Pharmacodynamics and Secretion of Hydrochloric Acid in Parietal Cells. Affiliated tissues include bone, heart and kidney.

Related Diseases for Cascade Stomach

Diseases related to Cascade Stomach via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 122)
# Related Disease Score Top Affiliating Genes
1 volvulus of midgut 29.5 ATP4A ATP12A
2 peptic esophagitis 28.8 HRH2 ATP4A ATP12A
3 pylorospasm 10.1
4 esophagitis 10.0
5 ovarian cancer 9.8
6 gastrointestinal ulceration, recurrent, with dysfunctional platelets 9.8
7 angina pectoris 9.8
8 deficiency anemia 9.8
9 gastric ulcer 9.8
10 diarrhea 9.8
11 pancreatic vasoactive intestinal peptide producing tumor 9.8 ATP4A ATP12A
12 hemangioma of intra-abdominal structure 9.8 ATP4A ATP12A
13 displacement of cardia through esophageal hiatus 9.8 ATP4A ATP12A
14 gastric hemangioma 9.8 ATP4A ATP12A
15 acquired gastric outlet stenosis 9.8 ATP4A ATP12A
16 angiodysplasia of intestine 9.8 ATP4A ATP12A
17 angiodysplasia 9.8 ATP4A ATP12A
18 benzylpenicillin allergy 9.8 ATP4A ATP12A
19 median arcuate ligament syndrome 9.8 ATP4A ATP12A
20 granulomatous gastritis 9.8 ATP4A ATP12A
21 bacterial esophagitis 9.8 ATP4A ATP12A
22 lingual goiter 9.8 ATP4A ATP12A
23 gastrojejunal ulcer 9.8 ATP4A ATP12A
24 fungal esophagitis 9.8 ATP4A ATP12A
25 gastric gastrinoma 9.8 ATP4A ATP12A
26 fungal gastritis 9.8 ATP4A ATP12A
27 superior mesenteric artery syndrome 9.8 ATP4A ATP12A
28 cervix erosion 9.8 ATP4A ATP12A
29 pneumatosis cystoides intestinalis 9.8 ATP4A ATP12A
30 dieulafoy lesion 9.8 ATP4A ATP12A
31 esophagus sarcoma 9.8 ATP4A ATP12A
32 esophagus melanoma 9.8 ATP4A ATP12A
33 necrotizing gastritis 9.8 ATP4A ATP12A
34 central nervous system origin vertigo 9.8 ATP4A ATP12A
35 cefuroxime allergy 9.8 ATP4A ATP12A
36 gastroduodenitis 9.8 ATP4A ATP12A
37 duodenitis 9.8 ATP4A ATP12A
38 chronic intestinal vascular insufficiency 9.8 ATP4A ATP12A
39 rumination disorder 9.8 ATP4A ATP12A
40 blind loop syndrome 9.8 ATP4A ATP12A
41 crab allergy 9.8 ATP4A ATP12A
42 acute laryngitis 9.8 ATP4A ATP12A
43 duodenal gastrinoma 9.8 ATP4A ATP12A
44 esophageal tuberculosis 9.8 ATP4A ATP12A
45 gastric dilatation 9.8 ATP4A ATP12A
46 diclofenac allergy 9.8 ATP4A ATP12A
47 internal hemorrhoid 9.8 ATP4A ATP12A
48 hemorrhoid 9.8 ATP4A ATP12A
49 lymphocytic gastritis 9.8 ATP4A ATP12A
50 duodenal obstruction 9.8 ATP4A ATP12A

Graphical network of the top 20 diseases related to Cascade Stomach:



Diseases related to Cascade Stomach

Symptoms & Phenotypes for Cascade Stomach

Drugs & Therapeutics for Cascade Stomach

Search Clinical Trials , NIH Clinical Center for Cascade Stomach

Genetic Tests for Cascade Stomach

Anatomical Context for Cascade Stomach

MalaCards organs/tissues related to Cascade Stomach:

40
Bone, Heart, Kidney, Skin, Cervix, B Cells

Publications for Cascade Stomach

Articles related to Cascade Stomach:

(show all 42)
# Title Authors PMID Year
1
Cascade stomach associated with delayed-on or no-on phenomenon in a patient with Parkinson's disease. 61
28782858 2017
2
Increase of transient lower esophageal sphincter relaxation associated with cascade stomach. 61
28584403 2017
3
New endoscopic classification of cascade stomach, a risk factor for reflux esophagitis. 61
27121685 2017
4
Cascade stomach is associated with upper gastrointestinal symptoms: a population-based study. 61
22288935 2012
5
[Cascade stomach - a rare cause of gastric pseudoobstruction]. 61
21181647 2011
6
Diagnostic accuracy of cascade stomach by upper gastrointestinal endoscopy in patients with obscure symptoms: a multi-center prospective trial. 61
21507743 2011
7
[Abdominal pain attacks and diarrhea disorders due to an internal stent draining of left kidney in a patient with a cascade stomach]. 61
22629710 2011
8
Laparoscopic sleeve resection of a recurrent gastric cascade: a case report. 61
17570775 2007
9
Duane anomaly, meningomyelocele, dextroposition of heart and localized vertebrocostal alterations with associated anomalies in a girl. 61
17515303 2007
10
"Cascade stomach": laparoscopic treatment. 61
9865577 1998
11
The most common cause of cascade stomach. 61
8566901 1994
12
[Gastric emptying in patients with cascade stomach]. 61
7177945 1982
13
[Kuntzen's operation in the treatment of cascade stomach]. 61
7281677 1981
14
Cascade stomach. Roentgen appearance and significance. 61
1147142 1975
15
[Cascade stomach. Considerations on 11 cases]. 61
5069490 1972
16
[Differential diagnostic significance of the cascade stomach in a typical upper abdominal complaints]. 61
4644537 1972
17
Symptomatic cascade stomach treated surgically. 61
5238577 1968
18
[Cascade stomach (case reports)]. 61
5621183 1967
19
[Cascade stomach as a radiologic-clinical problem]. 61
5993212 1966
20
[ON FLEXURE OF THE STOMACH ("CASCADE STOMACH") IN GASTRIC ULCER]. 61
14273955 1965
21
Role of gastric distention in angina pectoris. Intractable angina pectoris with cascade stomach and magenblase syndrome treated with gastric resection. 61
13938589 1963
22
[The cascade stomach]. 61
14005893 1962
23
[Cascade stomach as a symptom of ovarian carcinoma]. 61
13896633 1961
24
[Cascade stomach. Radiologic-clinical study apropos of 2 cases]. 61
13772193 1961
25
[Cardioesophageal syndrome with pylorospasm and cascade stomach]. 61
13742853 1960
26
[Contribution to the problem of the causal relationship between pylorospasm and cascade stomach]. 61
14442353 1960
27
[Cascade stomach]. 61
13841507 1960
28
[The cascade stomach and its surgical importance]. 61
14412786 1959
29
[A clinical significant form of cascade stomach (J. Marie's plicature gastrique of the infant)]. 61
13515559 1957
30
[Cascade stomach; examination of the red blood corpuscles and of hemoglobin]. 61
13421267 1957
31
[Cascade stomach; clinical and radiological study]. 61
13378121 1956
32
Some diagnostic difficulties in cases with cascade stomach and chronic gastric volvulus. 61
13355971 1956
33
[Anemia in individuals with cascade stomach]. 61
13290213 1955
34
[The causes of cascade stomach]. 61
13265088 1955
35
[Clinical significance of cascade stomach]. 61
14386069 1955
36
Kinking, rotation, and twisting of the stomach, with special reference to cascade stomach and chronic gastric volvulus. 61
13182208 1954
37
[Cascade stomach and pylorospasm]. 61
13222639 1954
38
[Cascade stomach due to spontaneously closed gastroenterostomy and pylorus stenosis]. 61
13159860 1954
39
[The cascade stomach]. 61
12989376 1952
40
[Cascade stomach]. 61
15439008 1950
41
Cascade Stomach. 61
20322141 1941
42
"Cascade Stomach" Associated with Impaired OEsophageal Emptying in a Case of "Nervous Indigestion". 61
20320552 1937

Variations for Cascade Stomach

Expression for Cascade Stomach

Search GEO for disease gene expression data for Cascade Stomach.

Pathways for Cascade Stomach

Pathways related to Cascade Stomach according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.62 HRH2 ATP4A
2 9.32 HRH2 ATP4A

GO Terms for Cascade Stomach

Biological processes related to Cascade Stomach according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 potassium ion import across plasma membrane GO:1990573 9.32 ATP4A ATP12A
2 cellular sodium ion homeostasis GO:0006883 9.26 ATP4A ATP12A
3 establishment or maintenance of transmembrane electrochemical gradient GO:0010248 9.16 ATP4A ATP12A
4 sodium ion export across plasma membrane GO:0036376 8.96 ATP4A ATP12A
5 cellular potassium ion homeostasis GO:0030007 8.62 ATP4A ATP12A

Molecular functions related to Cascade Stomach according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sodium:potassium-exchanging ATPase activity GO:0005391 9.16 ATP4A ATP12A
2 potassium-transporting ATPase activity GO:0008556 8.96 ATP4A ATP12A
3 potassium:proton exchanging ATPase activity GO:0008900 8.62 ATP4A ATP12A

Sources for Cascade Stomach

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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