CTRCT26
MCID: CTR110
MIFTS: 26

Cataract 26, Multiple Types (CTRCT26)

Categories: Eye diseases, Fetal diseases, Genetic diseases, Metabolic diseases, Nephrological diseases, Neuronal diseases, Oral diseases, Rare diseases

Aliases & Classifications for Cataract 26, Multiple Types

MalaCards integrated aliases for Cataract 26, Multiple Types:

Name: Cataract 26, Multiple Types 57 29
Cataract, Autosomal Recessive, Early-Onset, Pulverulent 57 13 70
Ctrct26 57 12
Cataract, Autosomal Recessive, Early-Onset, Pulverulent; Caar 57
Cataract 26 Multiple Types 12
Caar 57

Classifications:



External Ids:

Disease Ontology 12 DOID:0110246
OMIM® 57 605749
OMIM Phenotypic Series 57 PS116200
ICD10 32 Q12.0
MedGen 41 C1854003
UMLS 70 C1854003

Summaries for Cataract 26, Multiple Types

OMIM® : 57 A locus on chromosome 9q12-q22 has been found for multiple types of cataract in 1 family. These include cortical, pulverulent, nuclear, and posterior subcapsular cataracts. The preferred title/symbol for this entry was formerly 'Cataract, Autosomal Recessive, Early-Onset, Pulverulent; CAAR.' (605749) (Updated 20-May-2021)

MalaCards based summary : Cataract 26, Multiple Types, also known as cataract, autosomal recessive, early-onset, pulverulent, is related to coronary artery aneurysm and aneurysm. An important gene associated with Cataract 26, Multiple Types is CTPL1 (Cataract, Pulverulent (Autosomal Recessive, Early-Onset)). The drugs Citalopram and Dopamine have been mentioned in the context of this disorder. Affiliated tissues include eye, cortex and t cells.

Disease Ontology : 12 A cataract that has material basis in variation in the region 9q13-q22.

Related Diseases for Cataract 26, Multiple Types

Graphical network of the top 20 diseases related to Cataract 26, Multiple Types:



Diseases related to Cataract 26, Multiple Types

Symptoms & Phenotypes for Cataract 26, Multiple Types

Clinical features from OMIM®:

605749 (Updated 20-May-2021)

Drugs & Therapeutics for Cataract 26, Multiple Types

Drugs for Cataract 26, Multiple Types (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 12)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Citalopram Approved Phase 4 59729-33-8 2771
2
Dopamine Approved Phase 4 51-61-6, 62-31-7 681
3
Bupropion Approved Phase 4 34911-55-2, 34841-39-9 444
4
Dexetimide Withdrawn Phase 4 21888-98-2
5 Psychotropic Drugs Phase 4
6 Dopamine Agents Phase 4
7 Dopamine Uptake Inhibitors Phase 4
8 Serotonin Uptake Inhibitors Phase 4
9 Neurotransmitter Agents Phase 4
10 Antidepressive Agents Phase 4
11 Cytochrome P-450 Enzyme Inhibitors Phase 4
12
Serotonin Investigational, Nutraceutical Phase 4 50-67-9 5202

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Connectivity Affecting the Antidepressant REsponse (The CAARE Study) Completed NCT02332291 Phase 4 Escitalopram;Bupropion XL
2 Characterization of Adults for Asthma Microbiome Research Studies (CAARS) Recruiting NCT02887911
3 A Scalable mHealth Resource to Facilitate Behavioral and Emotional Recovery After Pediatric Traumatic Injury Not yet recruiting NCT04579198

Search NIH Clinical Center for Cataract 26, Multiple Types

Genetic Tests for Cataract 26, Multiple Types

Genetic tests related to Cataract 26, Multiple Types:

# Genetic test Affiliating Genes
1 Cataract 26, Multiple Types 29

Anatomical Context for Cataract 26, Multiple Types

MalaCards organs/tissues related to Cataract 26, Multiple Types:

40
Eye, Cortex, T Cells, Endothelial, Brain

Publications for Cataract 26, Multiple Types

Articles related to Cataract 26, Multiple Types:

(show all 36)
# Title Authors PMID Year
1
A progressive autosomal recessive cataract locus maps to chromosome 9q13-q22. 57
11179024 2001
2
Aortic Valve Replacement in Low-Risk Patients With Severe Aortic Stenosis Outside Randomized Trials. 61
33446305 2021
3
Transcriptome analysis of primary podocytes reveals novel calcium regulated regulatory networks. 61
32931033 2020
4
Usefulness of oral anticoagulation in patients with coronary aneurysms: Insights from the CAAR registry. 61
32902099 2020
5
A Deregulated Stress Response Underlies Distinct INF2-Associated Disease Profiles. 61
32444357 2020
6
Autoimmunity as a target for chimeric immune receptor therapy: A new vision to therapeutic potential. 61
31813654 2020
7
Chimeric Antigen Receptor Based Therapy as a Potential Approach in Autoimmune Diseases: How Close Are We to the Treatment? 61
33324420 2020
8
Milestones in Personalized Medicine in Pemphigus and Pemphigoid. 61
33505392 2020
9
Coronary artery aneurysms, insights from the international coronary artery aneurysm registry (CAAR). 61
31378382 2020
10
Actin dynamics during Ca2+-dependent exocytosis of endothelial Weibel-Palade bodies. 61
30465794 2019
11
Immunotherapy Deriving from CAR-T Cell Treatment in Autoimmune Diseases. 61
32083141 2019
12
La/SSB chimeric autoantibody receptor modified NK92MI cells for targeted therapy of autoimmune disease. 61
29673902 2018
13
Rationale and design of a multicenter, international and collaborative Coronary Artery Aneurysm Registry (CAAR). 61
28337781 2017
14
Surface characterization of polymers used in fabrication of interim prostheses after treatment with photopolymerized glaze. 61
27987770 2017
15
Calcium-mediated actin reset (CaAR) mediates acute cell adaptations. 61
27919320 2016
16
Mass Spectrometric Observation of Doubly Charged Alkaline-Earth Argon Ions. 61
27252087 2016
17
Abundance and Impact of Doubly Charged Polyatomic Argon Interferences in ICPMS Spectra. 61
27306032 2016
18
Reengineering chimeric antigen receptor T cells for targeted therapy of autoimmune disease. 61
27365313 2016
19
A laser microdissection-based workflow for FFPE tissue microproteomics: Important considerations for small sample processing. 61
26690073 2016
20
Feasibility of school-based computer-assisted robotic gaming technology for upper limb rehabilitation of children with cerebral palsy. 61
24964205 2016
21
Evaluation of an alternative technique to optimize direct bonding of orthodontic brackets to temporary crowns. 61
26352846 2015
22
Three acyltetronic acid derivatives: noncanonical cryptic polyketides from Aspergillus niger identified by genome mining. 61
25044953 2014
23
Fluorescence emission of Ca-atom from photodissociated Ca2 in Ar doped helium droplets. II. Theoretical. 61
23163375 2012
24
Citric acid antigen retrieval (CAAR) for tryptic peptide imaging directly on archived formalin-fixed paraffin-embedded tissue. 61
20597554 2010
25
Relaxation dynamics of photoexcited calcium deposited on argon clusters: theoretical simulation of time-resolved photoelectron spectra. 61
20121073 2010
26
Motor and cognitive functions of the neostriatum during bilateral blockade of its dopamine receptors. 61
18097763 2008
27
Locus heterogeneity in autosomal recessive congenital cataracts: linkage to 9q and germline HSF4 mutations. 61
15959809 2005
28
The effects of microinjection of the selective blocker of muscarinic M1 receptors pirenzepine into the neostriatum on the motor behavior of rats. 61
16342615 2005
29
Cytotoxic T-cell activity is not detectable in Venezuelan equine encephalitis virus-infected mice. 61
12573505 2003
30
A new concept of carbon dioxide accelerated ammonia release from liquid manure in pig house. 61
11345745 2000
31
Development and validation of a dynamic mathematical model of ammonia release in pig house. 61
11345731 2000
32
[The comparative characteristics of the effect of piracetam peptide analogs on the recovery of conditioned reflex activity in animals following damage to the frontal cortex and the electrophysiological characteristics of the brain integrative activity]. 61
1305458 1992
33
Kinetics and mechanism of Ca2+ binding to arsenazo III and antipyrylazo III. 61
6722180 1984
34
Kinetic scheme for Ca2+-arsenazo III interactions. 61
6838582 1983
35
Spectrophotometric determination of reaction stoichiometry and equilibrium constants of metallochromic indicators. II. The Ca2+-arsenazo III complexes. 61
17000162 1981
36
[The relationship between the formation of trace reactions and the functional state of rats of different genetic lines]. 61
1210681 1975

Variations for Cataract 26, Multiple Types

Expression for Cataract 26, Multiple Types

Search GEO for disease gene expression data for Cataract 26, Multiple Types.

Pathways for Cataract 26, Multiple Types

GO Terms for Cataract 26, Multiple Types

Sources for Cataract 26, Multiple Types

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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